7,8-didemethyl-8-hydroxy-5-deazariboflavin





Description


7,8-didemethyl-8-hydroxy-5-deazariboflavin, also known as Fo(α)-8-hydroxy-7,8-didemethyl-5-deazariboflavin, is a modified form of the vitamin riboflavin (vitamin B2). It is an organic compound with a chemical formula of C14H14N4O3. This compound is a derivative of the cofactor flavin mononucleotide (FMN), which plays a critical role in various biological processes, including energy production and metabolism. The modification of FMN to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin alters its spectral properties and its ability to participate in electron transfer reactions. 7,8-didemethyl-8-hydroxy-5-deazariboflavin is found in some microorganisms, where it functions as a cofactor in certain enzymatic reactions. It has been studied for its potential as a fluorescent probe for biological imaging, due to its unique optical properties and ability to bind to certain proteins and enzymes. Overall, while 7,8-didemethyl-8-hydroxy-5-deazariboflavin is not well known, its modification of the important cofactor FMN highlights the potential for modifications of essential biological molecules to play important roles in various cellular processes.


Chemical Formula:
C16H16N3O7
Molecular Weight:
362.318 Daltons
Monoisotopic Mass:
363.106649916 Daltons
SMILES:
C(O)C(O)C(O)C(O)CN3(C1(C(C(=O)[N-]C(=O)N=1)=CC2(=CC=C(O)C=C23)))
InChI:
1S/C16H17N3O7/c20-6-12(23)13(24)11(22)5-19-10-4-8(21)2-1-7(10)3-9-14(19)17-16(26)18-15(9)25/h1-4,11-13,20,22-24H,5-6H2,(H2,17,18,21,25,26)/p-1/t11-,12+,13-/m0/s1

Synonyms
  • FO
  • cosynthetic factor I
  • CF-I
  • F0 (incorrect)
  • Fo (incorrect)

Databases
MetaCyc:  CPD-7602
PubChem (CID):  46878524
ChEBI:  59904
Seed:  cpd15839
MetaNetX:  MNXM1996
KEGG:  C19154