3-hydroxy-3-methylbutanoate





Description


3-hydroxy-3-methylbutanoate, also known as beta-hydroxy-beta-methylbutyrate (HMB), is a chemical compound that is produced in the body during the metabolism of the amino acid leucine. It is a metabolite of leucine and is involved in the regulation of muscle protein synthesis and breakdown. HMB has been studied for its potential to promote muscle growth and prevent muscle wasting, particularly in older adults and people with certain medical conditions. It has also been investigated for its potential to improve athletic performance and reduce muscle damage and soreness. Several studies have suggested that HMB supplementation may increase muscle mass and strength, particularly when combined with resistance training. HMB has also been shown to have anti-catabolic effects, which means it may help prevent the breakdown of muscle tissue during periods of inactivity or illness. While HMB has been shown to have some promising effects, more research is needed to fully understand its potential benefits and safety. As with any supplement, it is important to consult with a healthcare professional before taking HMB.


Chemical Formula:
C5H9O3
Molecular Weight:
117.124 Daltons
Monoisotopic Mass:
118.0629941873 Daltons
SMILES:
CC(C)(O)CC(=O)[O-]
InChI:
1S/C5H10O3/c1-5(2,8)3-4(6)7/h8H,3H2,1-2H3,(H,6,7)/p-1

Synonyms
  • 3-hydroxy-3-methylbutyrate
  • β-hydroxyisovalerate
  • β-hydroxy-β-methylbutyrate
  • 3-hydroxyisovalerate

Databases
MetaCyc:  CPD-14642
ChEBI:  82957
PubChem (CID):  6950804
HMDB:  HMDB00754
MetaNetX:  MNXM36533
KEGG:  C20827