H2O + AMP → aldehydo-D-ribose 5-phosphate + adenine
(S)-3-hydroxy-(9Z)-octadecenoyl-CoA ← H2O + (2E,9Z)-octadecenoyl-CoA
H2O + pyridoxal + oxygen → hydrogen peroxide + 4-pyridoxate + H+
H2O + N1-acetylspermine + oxygen → hydrogen peroxide + propane-1,3-diamine + N-(3-acetamidopropyl)-4-aminobutanal
H2O + tetracenomycin A2 epoxyquinone → 4-dehydro-tetracenomycin C
H2O + ferrichrome + ATP → ferrichrome + phosphate + ADP
H2O + erythritol + ATP → phosphate + erythritol + ADP
H2O + S-methyl-5'-thioadenosine → 5-(methylsulfanyl)-α-D-ribose + adenine
H2O + D-glucose 6-sulfate → H+ + sulfate + β-D-glucopyranose
H2O + 2'-deoxycytidine + H+ → 2'-deoxyuridine + ammonium
H2O + 4-methylene-L-glutamine → 4-methylene-L-glutamate + ammonium
H2O + 3-methyl-2-oxobutanoate + 5,10-methylenetetrahydropteroyl mono-L-glutamate → 2-dehydropantoate + 5,6,7,8-tetrahydrofolate
H2O + VAI-1-2 → H+ + N-(octanoyl)-L-homoserine
H2O + S-adenosyl-L-methionine + 12-ethyl-71-hydroxy-8-propylbacteriochlorophyllide c → H+ + 5'-deoxyadenosine + L-methionine + 12-ethyl-71,71-dihydroxy-8-propylbacteriochlorophyllide c
H2O + (2Z,4E)-2-aminomuconate + H+ → (3E)-2-oxohex-3-enedioate + ammonium
3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-hydroxypropanoyl-CoA ← H2O + (2E)-3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]prop-2-enoyl-CoA
H2O + H+ + gluconapin → 2-butenyl-thiohydroximate-O-sulfate + α-D-glucopyranose
H2O + 1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine → 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol
H2O + petrobactin + ATP → petrobactin + phosphate + ADP
H2O + D-kanosamine 6-phosphate → phosphate + kanosamine
H2O + dodecyl sulfate → H+ + 1-dodecanol + sulfate
H2O + NAD(P)+ + (2S)-3-sulfolactaldehyde → 2 H+ + NAD(P)H + (2S)-3-sulfolactate
H2O + methylsalicylate → salicylate + methanol + H+
2 H2O + NAD+ + 1-piperideine → 5-aminopentanoate + NADH + H+
H2O + (Z)-1-(L-cystein-S-yl)-N-hydroxy-2-phenylethan-1-imine → pyruvate + H+ + ammonium + (Z)-2-phenyl-1-thioacetohydroximate
H2O + thiamine diphosphate + ATP → thiamine diphosphate + phosphate + ADP
H2O + (+)-bisdechlorogeodin → asterrate + H+
H2O + D-myo-inositol (1,4,5,6)-tetrakisphosphate → D-myo-inositol (1,4,5)-trisphosphate + phosphate
H2O + limonin + UDP-α-D-glucose → limonin 17-β-D-glucoside + H+ + UDP
H2O + D-mannitol + ATP → phosphate + D-mannitol + ADP
H2O + 4-hydroxybenzaldehyde + NAD+ → 2 H+ + NADH + 4-hydroxybenzoate
2 H2O + N-methylpyrrolidone + ATP → 4-methylaminobutanoate + H+ + phosphate + ADP
H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)hexan-1-imine → pyruvate + (E)-ω-(methylsulfanyl)hexyl-thiohydroximate + ammonium
H2O + 4-phosphooxy-L-threonine → 4-hydroxy-L-threonine + phosphate
isopentenyldehydrorhodopin + H2O + prenyl diphosphate → dihydrobisanhydrobacterioruberin + diphosphate
H2O + 3-hydroxypropanal → 3-hydroxypropanal hydrate
H2O + N,N'-diacetylchitobiose 6'-phosphate → N-acetyl-D-glucosamine-6-phosphate + N-acetyl-β-D-glucosamine
Cd2+ + H2O + ATP → Cd2+ + H+ + phosphate + ADP
H2O + bis(1L-myo-inositol) 3,1'-phosphate 1-phosphate → phosphate + bis(myo-inositol)-1,3'-phosphate
H2O + neocarratetraose 4-O-sulfate → neocarrabiose + neocarrabiose sulfate
H2O + (2E,6E)-farnesyl diphosphate → (3R,6E)-nerolidol + diphosphate
H2O + dATP → H+ + phosphate + dADP
Fe2+ + H2O + ATP → Fe2+ + phosphate + ADP
H2O + D-myo-inositol (1,2,6) trisphosphate → D-myo-inositol (1,2) bisphosphate + phosphate
H2O + ADP ribose 1'',2''-cyclic phosphate → H+ + ADP ribose 1''-phosphate
H2O + 3-(4-deoxy-β-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine → 4-deoxy-L-threo-hex-4-enopyranuronate + N-acetyl-β-D-glucosamine
H2O + oxygen + normetanephrine → hydrogen peroxide + 3-methoxy-4-hydroxyphenylglycolaldehyde + ammonium
H2O + phenylglyoxylyl-CoA → coenzyme A + phenylglyoxylate + H+
H2O + Nα-(3-hydroxy-3-methylhexanoyl)-L-glutamine → 3-hydroxy-3-methylhexanoate + L-glutamine
an oxidized electron donor + thymine + H2O → 5-methyl-barbiturate + a reduced electron donor + H+
H2O + Cu+ + ATP → H+ + Cu+ + phosphate + ADP
H2O + H+ + melamine → ammonium + ammeline
H2O + linamarin → 2-hydroxy-2-methylpropanenitrile + β-D-glucopyranose
trans,octacis-decaprenylphospho-β-D-ribofuranose 5-phosphate + H2O → trans,octacis-decaprenylphospho-β-D-ribofuranose + phosphate
an oxidized electron donor + H2O + 3-methylquinoline → 3-methyl-2-oxo-1,2-dihydroquinoline + a reduced electron donor
an oxidized electron donor + H2O + N-methyl-L-glutamate → a reduced electron donor + formaldehyde + L-glutamate
H2O + ATP + cob(I)inamide → H+ + phosphate + ADP + cob(I)inamide
H2O + 2,2-dichloroacetate → 2 H+ + 2 chloride + glyoxylate
H2O + D-myo-inositol 1,3,4,5,6-pentakisphosphate → D-myo-inositol (1,4,5,6)-tetrakisphosphate + phosphate
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)pentan-1-imine → glycine + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)pentan-1-imine
H2O + 2-O-(α-D-mannosyl)-3-phospho-D-glycerate → phosphate + 2-O-(α-D-mannosyl)-D-glycerate
4 H2O + 4 S0 + oxygen → 2 sulfite + 2 hydrogen sulfide + 4 H+
H2O + XLXG xyloglucan oligosaccharide → β-D-galactopyranose + XXXG xyloglucan oligosaccharide
H2O + D-myo-inositol (1,2,3,6) tetrakisphosphate → D-myo-inositol (1,2,6) trisphosphate + phosphate
H2O + S-(1-hydroxyhexan-3-yl)-L-cysteinylglycine → glycine + S-(1-hydroxyhexan-3-yl)-L-cysteine
H2O + (4-hydroxyphenyl)acetate → acetate + hydroquinone
2 lauroyl-CoA + H2O → 2 coenzyme A + (2R)-2-decyl-3-oxotetradecanoate + H+
H2O + 3-chlorobenzaldehyde + NAD+ → 2 H+ + NADH + 3-chlorobenzoate
2 an oxidized electron donor + 2 H2O + β-carotene → 2 a reduced electron donor + isozeaxanthin
H2O + acetaldehyde + NADP+ → 2 H+ + acetate + NADPH
H2O + 2-deoxy-D-glucono-1,5-lactone → 2-deoxygluconate + H+
H2O + NAD(P)+ + coniferaldehyde → 2 H+ + NAD(P)H + ferulate
H2O + huvastatin lactone → huvastatin acid + H+
H2O + 2'''-acetyl-6'''-hydroxyparomomycin → acetate + 6'''-hydroxyparomomycin
H2O + 1,6-anhydro-N-acetyl-β-muramate + ATP → N-acetyl-D-muramate 6-phosphate + H+ + ADP
2 H2O + ppGpp → 2 phosphate + pGp
H2O + (2E)-3-methyl-4,6-dioxohept-2-enedioate → citraconate + pyruvate + H+
H2O + ATP + citrate → phosphate + ADP + citrate
glycerone phosphate + H2O → dihydroxyacetone + phosphate
H2O + digallate → 2 gallate + H+
H2O + 3-phosphooxypyruvate → hydroxypyruvate + phosphate
H2O + β-D-fructose 2,6-bisphosphate → β-D-fructose-2-phosphate + phosphate
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)hexan-1-imine → L-seryl-glycine + (E)-ω-(methylsulfanyl)hexyl-thiohydroximate
H2O + L-ala-Gly-L-Ala-Gly → 2 L-alanyl-glycine
H2O + (2-aminobenzoyl)acetyl-CoA → coenzyme A + H+ + (2-aminobenzoyl)acetate
H2O + D-myo-inositol (1,3,4,5)-tetrakisphosphate → D-myo-inositol (1,3,4)-trisphosphate + phosphate
FADH2 + H2O + 3,5,6-trichloro-2-pyridinol + oxygen → 3 chloride + 4 H+ + FAD + 3,6-dihydroxypyridine-2,5-dione
H2O + adenosine 2',3'-cyclic monophosphate → H+ + adenosine 3'-monophosphate
H2O + D-sorbitol 6-phosphate → phosphate + D-sorbitol
H2O + adenosine 2',3'-cyclic monophosphate → H+ + adenosine 2'-monophosphate
H2O + mycophenolate mofetil → mycophenolate + H+ + 2-morpholinoethanol
H2O + geranylgeranyl diphosphate → α-cembratriene-ol + diphosphate
H2O + isopenicillin N → 6-aminopenicillanate + L-2-aminoadipate
2 coenzyme A + 2 H2O + 2 NAD+ + 2 oxygen + 9-cis, 11-trans-octadecadienoyl-CoA → 2 hydrogen peroxide + 2 NADH + 2 H+ + 2 acetyl-CoA + 5-cis, 7-trans-tetradecadienoyl-CoA
H2O + N1-acetylspermidine + oxygen → hydrogen peroxide + 3-acetamidopropanal + putrescine
H2O + 5-(4-acetoxybut-1-ynyl)-2-2'-bithiophene → acetate + 5-(4-hydroxybut-1-ynyl)-2,2'-bithiophene + H+
H2O + 2,6-dichlorohydroquinone + oxygen → 2 H+ + 2-chloromaleylacetate + chloride
Ni2+ + H2O + ATP → Ni2+ + phosphate + ADP
H2O + carbon disulfide → hydrogen sulfide + carbonyl sulfide
H2O + 3-sulfopropanal + NAD(P)+ → 2 H+ + 3-sulfopropanoate + NAD(P)H
H2O + H+ + 2-iminopropanoate → pyruvate + ammonium
(S)-2-chloropropanoate + H2O → H+ + (R)-lactate + chloride
H2O + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate → 1-guanidino-1-deoxy-scyllo-inositol + phosphate
H2O + estrone 3-sulfate → estrone + H+ + sulfate
H2O + GMP-N-ε-(N-α-acetyl lysine methyl ester) 5'-phosphoramidate → N-α-acetyl lysine methyl ester + GMP
H2O + D-myo-inositol (1,2,3,5,6) pentakisphosphate → D-myo-inositol (1,2,3,6) tetrakisphosphate + phosphate
H2O + glucosyl-oleandomycin → oleandomycin + β-D-glucopyranose
H2O + L-selenocystathionine → seleno-L-homocysteine + pyruvate + H+ + ammonium
H2O + (+)-7-epi-jasmonoyl-L-isoleucine → L-isoleucine + (+)-7-epi-jasmonate
H2O + acetaldehyde + NAD+ → 2 H+ + acetate + NADH
H2O + pheophytin b → phytol + H+ + pheophorbide b
2 H+ + H2O + 3-ureidopropanoate → β-alanine + ammonium + CO2
H2O + NADP+ + methylglyoxal → 2 H+ + NADPH + pyruvate
H2O + cyclobis-(1→6)-α-nigerosyl → α-isomaltosyl-(1→3)-isomaltose
H2O + 2-pentenoyl-CoA → (3R)-3-hydroxypentanoyl-CoA
1-hydroxychlorobactene ← chlorobactene + H2O
an oxidized electron donor + H2O + 2-furoyl-CoA → S-(5-hydroxy-2-furoyl)-CoA + a reduced electron donor
H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-ω-(methylsulfanyl)nonan-1-imine → L-glutamate + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)nonan-1-imine
H2O + N-acetyl-L-aspartate → acetate + L-aspartate
H2O + 2,6-dihydroxynicotinate + oxygen → maleamate + formate + H+ + CO2
H2O + formyl-CoA → coenzyme A + formate + H+
an oxidized electron donor + all-trans-lycopene + H2O + prenyl diphosphate → nonaflavuxanthin + a reduced electron donor + diphosphate
an oxidized electron donor + 17R-hydroperoxydocosahexaenoate + H2O → 4S-hydroperoxy,17R-hydroxydocosahexaenoate + a reduced electron donor
H2O + cyclic di-3',5'-guanylate → 5'-phosphoguanylyl(3'→5')guanosine + H+
H2O + methylglyoxal + oxygen → hydrogen peroxide + pyruvate + H+
H2O + nitrate + ATP → phosphate + nitrate + ADP
H2O + prenyl diphosphate → diphosphate + isoprenyl alcohol
9α-copalyl diphosphate + H2O → syn-copalol + diphosphate
H2O + crotonobetainyl-CoA → coenzyme A + crotono-betaine + H+
H2O + 3,5-dihydro-4H-imidazol-4-one + H+ → N-formimino-glycine
H2O + NADP+ + 16-oxo-palmitate → 2 H+ + NADPH + hexadecanedioate
H2O + 6-O-α-mycolyl-trehalose 6-phosphate → α, α'-trehalose 6-α-mycolate + phosphate
H2O + IMP → inosine + phosphate
2 H2O + 2 L-glutamine + 2 ATP + hydrogenobyrinate → 2 H+ + 2 L-glutamate + 2 phosphate + 2 ADP + hydrogenobyrinate a,c-diamide
H2O + D-sorbitol + ATP → phosphate + D-sorbitol + ADP
H2O + dihomo γ-linolenoyl-CoA → coenzyme A + H+ + di-homo-γ-linolenate
H2O + trans-5-O-caffeoyl-D-quinate → L-quinate + H+ + trans-caffeate
1D-1-O-(indol-3-yl)acetyl-myo-inositol + H2O → myo-inositol + H+ + (indol-3-yl)acetate
H2O + hydroxyatrazine + H+ → N-isopropylammelide + ethylamine
H2O + NAD+ + D-glyceraldehyde 3-phosphate → 2 H+ + NADH + 3-phospho-D-glycerate
H2O + β-nicotinate D-ribonucleotide → nicotinate + H+ + aldehydo-D-ribose 5-phosphate
H2O + L-methionine-(S)-S-oxide + ATP → L-methionine-(S)-S-oxide + H+ + phosphate + ADP
H2O + ATP + cob(I)alamin → phosphate + ADP + cob(I)alamin
H2O + ammonium + ubiquinone-10 → rhodoquinone-10 + CO2
an oxidized electron donor + H2O + D-arginine → a reduced electron donor + 5-guanidino-2-oxopentanoate + ammonium
H2O + O-[-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-D-glucose → N-acetylmuramate + N-acetyl-β-D-glucosamine
Mo2+ + H2O + ATP → Mo2+ + phosphate + ADP
H2O + benzaldehyde + oxygen → hydrogen peroxide + H+ + benzoate
H2O + L-isoleucine + ATP → L-isoleucine + phosphate + ADP
H2O + β-D-fructofuranose 1-phosphate → phosphate + β-D-fructofuranose
H2O + 4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate → 4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + H+ + sulfate
H2O + 6-hydroxy-2-(6-oxo-1-oxaspiro[2.5]octa-4,7-dien-2-yl)-1-benzofuran-3-one → 2-[hydroperoxy(4-hydroxyphenyl)methyl]-6-hydroxy-1-benzofuran-3-one
2 H2O + dATP → 2 H+ + 2 phosphate + dAMP
H2O + 4-aminophenol + H+ → hydroquinone + ammonium
2 a peptidoglycan dimer (S. aureus) + 3 H2O → 4 D-alanine + a peptidoglycan with D,D cross-link (S. aureus) + di-trans,octa-cis-undecaprenyl diphosphate + H+
H2O + indol-3-ylmethylisothiocyanate-[γ-Glu-Cys} → indol-3-ylmethylisothiocyanate-L-cysteine + L-glutamate
H2O + felinine → pyruvate + ammonium + 3-methyl-3-sulfanylbutan-1-ol
H2O + salicyl-6-hydroxy-2-cyclohexene-on-oyl → salicyl alcohol + H+ + 6-hydroxy-2-cyclohexen-one-carboxylate
H2O + S-methyl-L-cysteine + oxygen → hydrogen peroxide + methiin
H2O + (S)-6-hydroxynicotine + oxygen → hydrogen peroxide + 6-hydroxypseudooxynicotine
H2O + 3-(hydroxyphosphinoyl)pyruvate + acetyl-CoA → coenzyme A + H+ + 2-(phosphonoylmethyl)malate
FAD + H2O + trans-zeatin riboside + H+ → FADH2 + 3-methyl-4-trans-hydroxy-2-butenal + adenosine
H2O + 4-aminobutanal + NAD+ → 2 H+ + 4-aminobutanoate + NADH
H2O + 4,4'-(1E)-prop-1-ene-1,2-diyldiphenol + oxygen → S-1-(4-hydroxyphenyl)-ethanol + H+ + 4-hydroxybenzoate
H2O + fluoroacetyl-CoA → coenzyme A + fluoroacetate + H+
H2O + D-myo-inositol (1,3,4,5)-tetrakisphosphate → D-myo-inositol (1,4,5)-trisphosphate + phosphate
H2O + 9,10-epoxy-18-hydroxystearate → 9,10,18-trihydroxystearate
H2O + α-3',4'-anhydrovinblastine → vinblastine
H2O + chlorophyllide a → methanol + 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + CO2
2 NAD(P)+ + H2O + UDP-N-acetyl-α-D-galactosamine → 2 NAD(P)H + 3 H+ + UDP-N-acetyl-α-D-galactosaminouronate
H2O + L-homocysteine → 2-oxobutanoate + ammonium + hydrogen sulfide
H2O + 2-O-(α-D-glucopyranosyl)-3-phospho-D-glycerate → phosphate + 2-O-(α-D-glucopyranosyl)-D-glycerate
H2O + CMP-5'-3-(N-acetyl-N-hydroxy)aminopropylphosphonate → CMP + H+ + FR-900098
H2O + 2-(phosphinatomethylidene)butanedioate → 3-(hydroxyphosphonoylmethyl)malate
H2O + adenosylcobinamide → (R)-1-aminopropan-2-ol + adenosylcobyrate
4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl--D-galactosamine 6-sulfate + H2O → 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-D-galactosamine 6-O-sulfate
2 a peptidoglycan dimer (meso-diaminopimelate containing) + H2O → a peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + D-alanine
H2O + L-alanyl-L-aspartate → L-aspartate + L-alanine
H2O + L-glucono-1,5-lactone → L-gluconate + H+
benzyl 6-O-β-D-apiofuranosyl-β-D-glucopyranoside + H2O → β-D-apiofuranosyl-(1->6)-D-glucose + benzyl alcohol
H2O + (2-aminoethyl)phosphonate + ATP → (2-aminoethyl)phosphonate + phosphate + ADP
2 H2O + dGTP → 2 H+ + 2 phosphate + dGMP
H2O + N2-succinyl-L-glutamate 5-semialdehyde + NAD+ → 2 H+ + N2-succinylglutamate + NADH
H2O + ammonium + ATP → ammonium + phosphate + ADP
coenzyme A + H2O + 2-[(1R,6S)-1,6-dihydroxycyclohexa-2,4-dien-1-yl]acetyl-coA → H+ + acetyl-CoA + (3S)-hydroxyadipyl-CoA
2 H2O + acrylonitrile → acrylate + ammonium
H2O + dUTP → H+ + diphosphate + dUMP
H2O + 3-sulfinopyruvate → pyruvate + H+ + sulfite
H2O + linustatin → linamarin + β-D-glucopyranose
coenzyme A + H2O + NAD+ + (3R)-hydroxy-nonanoyl-CoA + oxygen → hydrogen peroxide + NADH + H+ + 3-hydroxy-heptanoyl-CoA + acetyl-CoA
H2O + 3-hydroxybenzaldehyde + NADP+ → 2 H+ + NADPH + 3-hydroxybenzoate
11-cis-retinyl palmitate + H2O → 11-cis-retinol + palmitate + H+
H2O + geranylgeranyl diphosphate → β-cembratriene-ol + diphosphate
H2O + cyclohexylamine + oxygen → hydrogen peroxide + cyclohexanone + ammonium
H2O + simvastatin lactone → simvastatin acid + H+
an oxidized electron donor + H2O + pyrithiamine → 4-amino-2-methyl-5-pyrimidinemethanol + a reduced electron donor + 2-(2-methylpyridin-3-yl)ethanol
H2O + (+)-7-epi-12-hydroxyjasmonoyl-L-isoleucine → cis-tuberonic acid + L-isoleucine
H2O + L-phenylalanine + ATP → L-phenylalanine + H+ + phosphate + ADP
H2O + S0 + ATP → phosphate + S0 + ADP
2 an oxidized electron donor + H2O + 8-carboxy-8-demethylriboflavin 5'-phosphate + L-glutamate → 2 a reduced electron donor + 8-amino-8-demethylriboflavin 5'-phosphate + 2-oxoglutarate + CO2
H2O + NAD+ + grixazone A → 2 H+ + NADH + grixazone B
7(8)-epoxy-17R-hydroxy-docosahexaenoate + H2O → aspirin triggered resolvin D2
7(8)-epoxy-17R-hydroxy-docosahexaenoate + H2O → aspirin triggered resolvin D1
H2O + S-(3-methylbutan-3-yl)-L-cysteinylglycine → glycine + felinine
H2O + S-benzyl-glutatione → glycine + S-benzyl-γ-glutamylcysteine
H2O + (R)-3-((R)-3-hydroxybutanoyloxy)-butanoate → 2 (R)-3-hydroxybutanoate + H+
H2O + glycyl-L-glutamate → glycine + L-glutamate
H2O + 2-oxepin-2(3H)-ylideneacetyl-CoA → 3-oxo-5,6-didehydrosuberyl-CoA semialdehyde
H2O + 4-methylumbelliferyl acetate → 4-methylumbelliferone + acetate + H+
H2O + N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanine → N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysine + D-alanine
2-hydroxy-6-oxo-nona-2,4-dienoate + H2O → butanoate + H+ + (2Z)-2-hydroxypenta-2,4-dienoate
H2O + α-L-arabinopyranose + ATP → phosphate + α-L-arabinopyranose + ADP
H2O + S-(4-hydroxy-2-methylpentan-2-yl)-L-cysteine → pyruvate + ammonium + 4-methyl-4-sulfanylpentan-2-ol
H2O + serinol phosphate → serinol + phosphate
H2O + an acyl-CoA → a carboxylate + coenzyme A + H+
H2O + versiconal hemiacetal acetate → acetate + H+ + versiconal
H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)heptan-1-imine → pyruvate + (E)-ω-(methylsulfanyl)heptyl-thiohydroximate + ammonium
H2O + β-D-galactofuranose + ATP → β-D-galactofuranose + H+ + phosphate + ADP
H2O + succinamate → ammonium + succinate
H2O + S-lactoyl-trypanothione → trypanothione + (R)-lactate
H2O + theobromine + oxygen → hydrogen peroxide + 3,7-dimethylurate
H2O + NAD+ + 3-formyl-4-hydroxybenzoate → 2 H+ + NADH + 4-hydroxyisophthalate
H2O + furfural → 2-(dihydroxymethyl)furan
H2O + 7,2'-dihydroxy-4',5'-methylenedioxyisoflav-3-ene → 7,2,2'-trihydroxy-4',5'-methylenedioxyisoflav-3-ene
an oxidized electron donor + H2O + (R)-nicotine → (R)-6-hydroxynicotine + a reduced electron donor
H2O + nigerose → 2 α-D-glucopyranose
H2O + 1-stearoyl-sn-glycerol 3-phosphate → 1-stearoyl-sn-glycerol + phosphate
H2O + NAD+ + 3-dimethylsulfoniopropionaldehyde → 2 H+ + dimethylsulfoniopropanoate + NADH
H2O + 3-(glutathion-S-yl)-(3-methyl)butanol → L-glutamate + S-(3-methylbutan-3-yl)-L-cysteinylglycine
2 H2O + (2E,6E)-farnesyl diphosphate → diphosphate + 7-epi-ent-eudesmane-5,11-diol
H2O + oxygen + tyramine → hydrogen peroxide + (4-hydroxyphenyl)acetaldehyde + ammonium
maltoheptaose + H2O → maltohexaose + α-D-glucopyranose
H2O + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate → (S)-4-hydroxy-2-oxohexanoate
H2O + L-alanyl-γ-D-glutamyl-meso-diaminopimelate + ATP → L-alanyl-γ-D-glutamyl-meso-diaminopimelate + H+ + phosphate + ADP
maltotriose + H2O + ATP → maltotriose + H+ + phosphate + ADP
H2O + epoxypheophorbide a → red chlorophyll catabolite
H2O + (2E,9Z)-hexadecenoyl-CoA → (S)-3-hydroxy-(9Z)-hexadecenoyl-CoA
(3S)-citramalyl-CoA ← H2O + itaconyl-CoA
3 H2O + XXXG xyloglucan oligosaccharide → 3 isoprimeverose + β-D-glucopyranose
2 S-adenosyl-L-methionine + H2O + (31R)-8-ethyl-12-methylbacteriochlorophyllide c → 2 H+ + 2 5'-deoxyadenosine + 2 L-methionine + (31R)-8-ethyl-12-methylbacteriochlorophyllide e
H2O + atrazine → hydroxyatrazine + H+ + chloride
H2O + H+ + malonyl-CoA + (S)-1-pyrroline-5-carboxylate → coenzyme A + (2S,5S)-5-carboxymethyl proline + CO2
H2O + geranylgeranyl diphosphate → ent-16-a-hydroxy-kaurene + diphosphate
H2O + dGTP → H+ + triphosphate + 2'-deoxyguanosine
2-chloro-5-methyl-dienelactone + H2O → 2-chloro-5-methyl-maleylacetate + H+
H2O + a partially deacetylated poly-β-1,6-N-acetyl-D-glucosamine I → a partially deacetylated poly-β-1,6-N-acetyl-D-glucosamine (fragment 1) + a partially deacetylated poly-β-1,6-N-acetyl-D-glucosamine (fragment 2)
(+)-copalyl diphosphate + H2O → manool + diphosphate
2 an oxidized ferredoxin [iron-sulfur] cluster + phosphate + ADP + bacteriochlorophyllide a ← 2 a reduced ferredoxin [iron-sulfur] cluster + H2O + H+ + ATP + 3-acetyl-3-devinylchlorophyllide a
H2O + adenosylcobalamin 5'-phosphate → adenosylcobalamin + phosphate
H2O + presqualene diphosphate → hydroxysqualene + diphosphate
H2O + 2-hydroxy-7-methyl-6-oxo-2,4-octadienoate → isobutanoate + 2-oxopent-4-enoate + H+
6-caprolactam + H2O → 6-aminohexanoate
H2O + L-alanyl-L-glutamate → L-alanine + L-glutamate
H2O + enterobactin → N-(2,3-dihydroxybenzoyl)-L-serine trimer + H+
H2O + cyclohex-1-ene-1-carbonyl-CoA → 2-hydroxy-cyclohexane-1-carbonyl-CoA
H2O + prostaglandin F2α + ATP → prostaglandin F2α + phosphate + ADP
an oxidized electron donor + H2O + ethylbenzene → (S)-1-phenylethanol + a reduced electron donor
H2O + 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate → 6 H+ + 3-hydroxy-2-methylpyridine-4,5-dicarboxylate
H2O + 7,8-dihydroneopterin 3'-phosphate → 7,8-dihydroneopterin + phosphate
coenzyme A + H2O + NAD+ + (S)-methylmalonate-semialdehyde → propanoyl-CoA + NADH + H+ + hydrogencarbonate
H2O + ureidomalonate → ammonium + 1-carboxymalonamate
H2O + 2''-O-acetyl-ADP-ribose → acetate + H+ + ADP-D-ribose
H2O + D-myo-inositol 1,3,4,5,6-pentakisphosphate → D-myo-inositol (3,4,5,6)-tetrakisphosphate + phosphate
H2O + agarohexaose → neoagarotriose + agarotriose
2 H2O + 3-(methylsulfanyl)acryloyl-CoA → coenzyme A + acetaldehyde + methanethiol + CO2
H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-ω-(methylsulfanyl)hexan-1-imine → L-glutamate + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)hexan-1-imine
H2O + 1,4-dihydroxy-2-naphthoyl-CoA → coenzyme A + 1,4-dihydroxy-2-naphthoate + H+
H2O + polyneuridine aldehyde → 16-epivellosimine + methanol + CO2
H2O + 3''-O-acetyl-ADP-ribose → acetate + H+ + ADP-D-ribose
3 H2O + 4 Fe3+ + S-sulfanylglutathione → 4 Fe2+ + 6 H+ + glutathione + sulfite
H2O + (-)-methyl jasmonate → methanol + H+ + (-)-jasmonate
coenzyme A + H2O + NAD+ + 3-hydroxy-heptanoyl-CoA + oxygen → hydrogen peroxide + NADH + 3-hydroxy-pentanoyl-CoA + H+ + acetyl-CoA
H2O + 2-hydroxy-5-nitro-6-oxohepta-2,4-dienoate → acetate + 2-hydroxy-5-nitropenta-2,4-dienoate + H+
H2O + selenide + ATP → selenophosphate + phosphate + AMP
H2O + β-alaninamide → β-alanine + ammonium
H2O + 4-methylaminobutanoate + oxygen → succinate semialdehyde + methylamine + hydrogen peroxide
H2O + formaldehyde + NAD+ → 2 H+ + NADH + formate
H2O + L-alanyl-L-leucine → L-leucine + L-alanine
H2O + 3-hydroxy-4-methylbenzaldehyde + NADP+ → 2 H+ + NADPH + 3-hydroxy-4-methyl-benzoate
H2O + bis-D-fructos 2',1:2,1'-dianhydride → inulobiose
H2O + geranyl diphosphate → geranyl monophosphate + H+ + phosphate
H2O + (L-cysteinylglycin-S-yl)(1H-indol-3-yl)acetonitrile → glycine + 2-(cystein-S-yl)-2-(1H-indol-3-yl)-acetonitrile
H2O + maltitol + ATP → maltitol + phosphate + ADP
H2O + NAD+ + hypoxanthine → xanthine + NADH + H+
N4-(β-N-acetyl-D-glucosaminyl)-L-asparagine + H2O → N-acetyl-β-D-glucosamine + L-asparagine
H2O + 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene → acetate + 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + H+
H2O + 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one → 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate + H+
Co2+ + H2O + hydrogenobyrinate a,c-diamide + ATP → 3 H+ + phosphate + ADP + cob(II)yrinate a,c-diamide
H2O + selenate + ATP → H+ + phosphate + selenate + ADP
2 an oxidized electron donor + 2 H2O + 4,4'-diapolycopen-4,4'-dial → 2 a reduced electron donor + 2 H+ + 4,4'-diapolycopenedioate
H2O + glycerol 2-phosphate + ATP → glycerol 2-phosphate + H+ + phosphate + ADP
2 H2O + dCTP → 2 H+ + 2 phosphate + dCMP
H2O + 3-hydroxy-5-methylbenzaldehyde + NADP+ → 2 H+ + NADPH + 3-hydroxy-5-methyl-benzoate
H2O + phenylethyl acetate → acetate + 2-phenylethanol + H+
H2O + S-adenosyl-L-methionine + (31R)-8,12-diethylbacteriochlorophyllide c → H+ + 5'-deoxyadenosine + L-methionine + (31R)-8,12-diethyl-71-hydroxybacteriochlorophyllide c
3-hydroxy-L-kynurenine + H2O → 3-hydroxyanthranilate + H+ + L-alanine
H2O + UDP-N,N'-diacetylbacillosamine → 2,4-diacetamido-2,4,6-trideoxy-α-D-mannopyranose + H+ + UDP
H2O + β-L-arabinofuranosyl-(1→2)-β-L-arabinofuranosyl-(1→2)-β-L-arabinofuranosyl-(2S,4S)-4-hydroxyproline → β-L-arabinofuranosyl-(1→2)-β-L-arabinofuranose + β-L-arabinofuranosyl-(2S,4S)-4-hydroxyproline
H2O + (glutathion-S-yl)-bimane → L-glutamate + S-bimane-L-cysteinylglycine
an oxidized electron donor + H2O + 3-dimethylselenopropionaldehyde → dimethylselenoniopropanoate + a reduced electron donor + H+
H2O + iminoarginine → 5-guanidino-2-oxopentanoate + ammonium
H2O + 2-O-(6-phospho-α-D-mannosyl)-D-glycerate → (R)-glycerate + α-D-mannopyranose 6-phosphate
H2O + 3-hydroxypropanal + NAD+ → 2 H+ + 3-hydroxypropanoate + NADH
H2O + 5''-phosphoribostamycin → phosphate + ribostamycin
H2O + quercitrin → quercetin + β-L-rhamnopyranose
H2O + L-alanyl-L-threonine → L-threonine + L-alanine
2 an oxidized electron donor + 18'-hydroxy-χ,χ-caroten-18-oate + H2O → 2 a reduced electron donor + synechoxanthin + H+
H2O + cyclic-AMP → ammonia + cyclic-IMP
H2O + NADP+ + (S)-lactaldehyde → 2 H+ + NADPH + (S)-lactate
H2O + neoagarotetraose → agarotriose + 3,6-anhydro-α-L-galactopyranose
H2O + methanethiol + oxygen → hydrogen peroxide + formaldehyde + hydrogen sulfide
H2O + NAD+ + 2-(glutathion-S-yl)-2-methylbut-3-enal → 2 H+ + NADH + 2-(glutathion-S-yl)-2-methylbut-3-enoate
H2O + 2,4-diacetylphloroglucinol → acetate + 2-acetylphloroglucinol + H+
phosphoenolpyruvate + H2O + aldehydo-D-arabinose 5-phosphate → 3-deoxy-D-manno-octulosonate 8-phosphate + phosphate
H2O + 6-hydroxy-N-methylmyosmine → 6-hydroxypseudooxynicotine
H2O + hydroxypyruvaldehyde phosphate + NAD+ → 2 H+ + 3-phosphooxypyruvate + NADH
H2O + 4-trimethylammoniobutanal + NAD+ → 2 H+ + γ-butyrobetaine + NADH
glycerophosphoglycerol + H2O → glycerol + H+ + sn-glycerol 3-phosphate
H2O + fusaridione A → fusaridione A (open ring)
an oxidized electron donor + H2O + 4-methylphenol → 2 H+ + 4-hydroxybenzaldehyde + a reduced electron donor
H2O + 3-(glutathion-S-yl)-3-methylhexan-1-ol → L-glutamate + S-(6-hydroxy-4-methylhexan-4-yl)-L-cysteinylglycine
H2O + 4-hydroxylaminobenzoate + H+ → protocatechuate + ammonium
4 Fe2+ + 6 H2O + oxygen → 4 [FeO(OH)] monomer + 8 H+
H2O + lisdexamfetamine → L-lysine + (S)-amphetamine
H2O + (E)-4-coumaroyl-CoA + H+ + malonyl-CoA → 2 coenzyme A + 2 CO2 + 4-hydroxybenzalacetone
H2O + L-alanyl-L-histidine → L-alanine + L-histidine
H2O + oxygen + (indol-3-yl)acetaldehyde → hydrogen peroxide + H+ + (indol-3-yl)acetate
H2O + CDP-glycerol → 2 H+ + CMP + sn-glycerol 3-phosphate
2 H2O + thiocyanate + H+ → ammonium + OH- + carbonyl sulfide
H2O + 9,10-epoxy-10,12Z-octadecadienoate → 9-hydroxy-10-oxo-12-octadecenoate
H2O + 5-oxo-2-furoyl-CoA → H+ + (2Z)-2-hydroxypent-2-enedioyl-CoA
H2O + phosphorylated MMF3 butenolide intermediate → MMF3 butenolide intermediate + phosphate
tetrahymanol ← H2O + squalene
H2O + homocarnosine → 4-aminobutanoate + L-histidine
H2O + S-(4-nitrobenzyl)-glutatione → L-glutamate + S-(4-nitrobenzyl)-L-cysteinylglycine
H2O + α-D-xylopyranose + ATP → α-D-xylopyranose + phosphate + ADP
H2O + D-glucaro-1,5-lactone → H+ + D-glucarate
H2O + octanoyl-CoA + isopenicillin N → coenzyme A + penicillin K + L-2-aminoadipate + H+
H2O + cyanuric acid → biuret + CO2
H2O + (-)-medicarpin-3-O-glucoside-6''-malonate → malonate + (-)-medicarpin-3-O-glucoside + H+
H2O + GTP → H+ + diphosphate + GMP
2 H2O + N-methylhydantoin + ATP → 2 H+ + N-carbamoylsarcosine + phosphate + ADP
H2O + L-glutamine + ATP + nicotinate adenine dinucleotide → NAD+ + H+ + L-glutamate + diphosphate + AMP
coenzyme A + H2O + chrysanthemyl diphosphate → (1R,3R)-chrysanthemoyl CoA + diphosphate
H2O + choloyl-CoA → coenzyme A + H+ + cholate
H2O + myristoyl-CoA → coenzyme A + myristate + H+
2 NAD+ + H2O + UDP-N-acetyl-α-D-glucosamine → 2 NADH + 3 H+ + UDP-N-acetyl-α-D-glucosaminouronate
FMN + H2O → riboflavin + phosphate
H2O + 5-phospho-α-D-ribose 1,2-cyclic phosphate → D-ribofuranose 2,5-bisphosphate + H+
H2O + sulfinylidenemethanethione → H+ + monothiocarbonate + S0
H2O + 2'''-acetyl-6'''-deamino-6'''-hydroxyneomycin C → acetate + 6'''-deamino-6'''-hydroxyneomycin C
H2O + (2Z,4E)-2-amino-5-methyl-muconate semialdehyde + NAD+ → 2 H+ + NADH + (2Z,4E)-2-amino-5-methyl-muconate
H2O + choline + ATP → choline + phosphate + ADP
H2O + cytidine 2',3'-cyclic monophosphate → cytidine 2'-monophosphate + H+
3 H2O + trimethylaminoacetone → 9 H+ + glycine betaine + CO2
H2O + 2-(glutathion-S-yl)-propene → glycine + γ-L-glutamyl-[(S)-allyl]-L-cysteine
GDP-2,4-diacetamido-2,4,6-trideoxy-α-D-glucopyranose + H2O → 2,4-diacetamido-2,4,6-trideoxy-α-D-mannopyranose + H+ + GDP
H2O + monoglucosyl-enterobactin → monoglucosyl-(2,3-dihydroxybenzoylserine)3 + H+
H2O + (2E,4Z)-2-hydroxy-6-oxohepta-2,4-dienoate → acetate + 2-oxopent-4-enoate + H+
H2O + gentisyl-CoA → coenzyme A + gentisate + H+
H2O + cobalt-precorrin-5A → acetaldehyde + H+ + cobalt-precorrin-5B
H2O + sulfoacetaldehyde + NAD+ → 2 H+ + NADH + sulfoacetate
H2O + 2'-deoxymugineate → avenate A
H2O + cis-vaccenyl acetate → acetate + cis-vaccenyl alcohol + H+
formamide ← H2O + hydrogen cyanide
H2O + H+ + 2'-deoxyadenosine → ammonium + 2'-deoxyinosine
H2O + (S)-5-hydroxyisourate → H+ + (S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline
kievitone hydrate ← kievitone + H2O + H+
H2O + 2-(glutathion-S-yl)-2-carboxypropane → glycine + γ-L-glutamyl-(S)-2-carboxypropyl-L-cysteine
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine → glycine + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine
H2O + N1-(3-aminopropyl)agmatine → spermidine + urea
H2O + (2R)-phospho-3-sulfolactate → (2R)-3-sulfolactate + phosphate
an oxidized electron donor + H2O + indole-3-glycol aldehyde → a reduced electron donor + H+ + indole-3-glycolate
2 H+ + 3 malonyl-CoA + H2O + (E)-4-coumaroyl-CoA → 3 CO2 + 4 coenzyme A + p-coumaroyltriacetate
H2O + 8-(methylsulfanyl)-2-oxooctanoate + acetyl-CoA → coenzyme A + 2-[(6'-methylsulfanyl)hexyl]malate + H+
4-imidazolone-5-propanoate ← H2O + urocanate
(8S,9S,10S)-8,10-dimethyl-1-octalin + H2O → (-)-geosmin
H2O + glycyrrhizin → 1,2-β-D-glucosyluronate-D-glucuronate + glycyrrhetinate
H2O + 2-[2-O-(α-D-mannopyranosyl)-(1→2)-α-D-glucopyranosyl]-3-phospho-D-glycerate → phosphate + 2-[2-O-(α-D-mannopyranosyl)-(1→2)-α-D-glucopyranosyl]-D-glycerate
2 H2O + 2 NAD+ + bixin aldehyde → 2 NADH + 4 H+ + norbixin
H2O + glutarate semialdehyde + NADP+ → 2 H+ + glutarate + NADPH
H2O + uridine 2'3'-cyclic monophosphate → uridine 2'-monophosphate + H+
H2O + ATP + adenosine 5'-phosphosulfate → phosphate + ADP + adenosine 5'-phosphosulfate
H2O + D-cystine + ATP → D-cystine + H+ + phosphate + ADP
H2O + S-(2E,6E)-farnesyl-L-cysteine + oxygen → hydrogen peroxide + (2E,6E)-farnesal + L-cysteine
H2O + (3Z)-5-chloro-2-oxopent-3-enoate → 5-chloro-4-hydroxy-2-oxopentanoate
unsaturated archaetidylinositol phosphate + H2O → unsaturated archaetidylinositol + phosphate
an oxidized electron donor + 4,4'-diapolycopen-4-al-4'-oate + H2O → a reduced electron donor + H+ + 4,4'-diapolycopenedioate
maltopentaose + H2O → maltotetraose + α-D-glucopyranose
H2O + uridine 3'-monophosphate → uridine + phosphate
3 L-(4-hydroxyphenyl)glycine + 5 ATP + H2O + L-serine + L-arginine → 5 H+ + 5 diphosphate + 5 AMP + L-4-hydroxyphenylglycine-L-arginyl-D-4-hydroxyphenylglycine-L-seryl-L 4-hydroxyphenylglycine
H2O + (2Z,4Z)-2-amino-5-chlorohexa-2,4-dienedioate + H+ → (2Z,4Z)-2-chloro-5-hydroxyhexa-2,4-dienedioate + ammonium
H2O + melatonin → acetate + H+ + 5-methoxytryptamine
H2O + N-(4-oxoglutaryl)-L-cysteinylglycine → L-cysteinylglycine + 2-oxoglutarate
H2O + UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose → 2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose + H+ + UDP
(S)-3-hydroxyhexadecanoyl-CoA ← H2O + (2E)-hexadecenoyl-CoA
H2O + H+ + barbiturate → ureidomalonate
2 NAD+ + H2O + 6,8-dihydroxypurine → 2 NADH + 2 H+ + urate
H2O + linoleoyl-CoA → coenzyme A + H+ + linoleate
H2O + D-myo-inositol (1,2,3,5,6) pentakisphosphate → D-myo-inositol (1,2,5,6) tetrakisphosphate + phosphate
lupan-3β,20-diol ← H2O + (3S)-2,3-epoxy-2,3-dihydrosqualene
glycerophosphoserine + H2O → H+ + L-serine + sn-glycerol 3-phosphate
H2O + H+ + ETH-NAD-imine adduct → ammonium + ETH-NAD adduct
H2O + geranyl diphosphate → diphosphate + (-)-(4S)-α-terpineol
H2O + geranyl diphosphate → diphosphate + (+)-α-terpineol
H2O + 4-methylaminobutanoate + oxygen → hydrogen peroxide + 4-aminobutanoate + formaldehyde
H2O + N6-dimethylallyladenine + ATP → N6-dimethylallyladenine + phosphate + ADP
maltotriose + H2O → maltose + α-D-glucopyranose
H2O + [(3S)-4-(6-methyloctanoyl)-5-oxooxolan-3-yl]methyl phosphate → 6-dehydro-SCB3 + phosphate
H2O + cyclic ADP-ribose → H+ + ADP-D-ribose
H2O + pseudooxynicotine + oxygen → methylamine + hydrogen peroxide + 4-oxo-4-(pyridin-3-yl)butanal
melibiose + H2O → β-D-galactopyranose + β-D-glucopyranose
(S)-3-hydroxy-(7Z)-tetradecenoyl-CoA ← H2O + (2E,7Z)-tetradecenoyl-CoA
2 a peptidoglycan dimer (mycobacteria) + 4 H2O → 4 D-alanine + a peptidoglycan with D,D cross-links (mycobacteria) + H+ + mono-trans,octa-cis-decaprenyl diphosphate
H2O + N,N',N''-triacetylchitotriose → acetate + N,N''-diacetylchitotriose
H2O + ADP ribose 1''-phosphate → phosphate + ADP-D-ribose
H2O + sinapaldehyde + NADP+ → 2 H+ + NADPH + sinapate
H2O + glucosyl-oleandomycin + ATP → H+ + glucosyl-oleandomycin + phosphate + ADP
H2O + L-cystathionine → ammonia + 2-oxobutanoate + H+ + L-cysteine
H2O + glycine + ATP → glycine + phosphate + ADP
H2O + aclacinomycin A → methanol + H+ + 15-demethoxy-aclacinomycin A
H2O + 3-chlorocatechol + oxygen → 3 H+ + (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + chloride
H2O + acetoacetyl-CoA → coenzyme A + H+ + acetoacetate
(9Z,15Z)-12,13-epoxy-octadeca-9,15-dienoate + H2O → (9Z,15Z)-12,13-dihydroxyoctadeca-9,15-dienoate
dichlorocarbene + H2O → 2 H+ + 2 chloride + carbon monoxide
1-palmitoyl-2-linoleoyl-phosphatidylcholine + H2O → 1-linoleoyl-sn-glycero-3-phosphocholine + palmitate + H+
H2O + Coα-[α-(5-methoxybenzimidazolyl)]-Coβ-adenosylcobamide 5'-phosphate → Coα-[α-(5-methoxybenzimidazolyl)]-Coβ-adenosylcobamide + phosphate
H2O + 2,4,6-trioxohexanoate → acetylpyruvate + formate + H+
8 H2O + α-D-Man-(1→2)-α-D-Man-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→2)-α-D-Man-(1→6)]-α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-α-D-glucosaminylamine → 8 α-D-mannopyranose + β-1,4-D-mannopyranosyl-β-1,4-N-acetyl-D-glucosaminyl-β-1,4-N-acetyl-D-glucosaminylamine
17-hydroxy-3-oxo-4-pregnane-20-carboxyl-CoA ← H2O + 3-oxo-4,17-pregnadiene-20-carboxyl-CoA
H2O + N-acetyl-α-D-muramoyl-L-alanine(1-) → N-acetylmuramate + L-alanine
H2O + cetraxate benzyl ester → benzyl alcohol + H+ + cetraxate
H2O + 3-chlorobenzoate → H+ + chloride + 3-hydroxybenzoate
H2O + mannosylfructose-phosphate → mannosylfructose + H+ + phosphate
H2O + unsaturated gellan tetrasaccharide → 5-dehydro-4-deoxy-D-glucuronate + β-D-Glcp-(1→4)-α-L-Rhap-(1→3)-D-Glcp
H2O + 1-carboxybiuret → ammonium + 1,3-dicarboxyurea
H2O + oxygen + desoxyhemigossypol → hydrogen peroxide + hemigossypol
H2O + α -allenylagmatine + ATP → α -allenylagmatine + phosphate + ADP
H2O + (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene → (1S,4R)-2,4,5-trichloro-2,5-cyclohexadiene-1-diol + H+ + chloride
H2O + L-phenylalanine + H+ + oxygen → hydrogen peroxide + phenylacetaldehyde + ammonium + CO2
H2O + 5''-phosphoribosylparomamine → phosphate + 5-ribosylparomamine
H2O + succinate semialdehyde + NAD(P)+ → 2 H+ + NAD(P)H + succinate
H2O + CTP → H+ + phosphate + CDP
(3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA ← (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O
H2O + HAI-1 → H+ + N-(3-hydroxybutanoyl)-L-homoserine
H2O + protoheme + (2E,6E)-farnesyl diphosphate → diphosphate + ferroheme o
H2O + L-phenylalanine + oxygen → ammonia + hydrogen peroxide + 3-phenyl-2-oxopropanoate + H+
H2O + S-(+)-3,6,8-trimethylallantoin → 1,6,8-trimethylallantoate + H+
H2O + GTP → H+ + phosphate + GDP
2 H2O + 2 N6-acetyl-N6-hydroxy-L-lysine + 4 ATP + citrate → 4 H+ + 4 phosphate + 4 ADP + aerobactin
H2O + toyocamycin → sangivamycin
H2O + lanosteryl oleate → lanosterol + oleate + H+
H2O + NAD+ + 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate → 3-dehydroquinate + NADH + H+ + ammonium
H2O + S-adenosyl-L-homocysteine → L-homocysteine + adenosine
H2O + CMP-5'-phosphonoformate + 3-phospho-D-glycerate → CMP + 2-phosphono-formylglycerate + H+ + phosphate
2 an oxidized electron donor + 2 H2O + 3,4,3',4'-tetradehydro-β,β-carotene → 2 a reduced electron donor + 3,4,3',4'-tetradehydroisozeaxanthin
2 an oxidized electron donor + 2 H+ + H2O + 4-(3-methylbut-2-enyl)-L-abrine → 2 a reduced electron donor + CO2 + chanoclavine-I
D-arabinono-1,4-lactone + H2O → H+ + D-arabinonate
H2O + 4,15-diacetylnivalenol → acetate + H+ + 4-acetylnivalenol
H2O + taurocholate → taurine + cholate
H2O + phosphorylated SCB1 butanolide intermediate → SCB1 butanolide intermediate + phosphate
H2O + acetyl-CoA + oxaloacetate → coenzyme A + H+ + citrate
H2O + L-homoserine + ATP → L-homoserine + phosphate + ADP
H2O + S-trans-1-propenyl-L-cysteine + oxygen → hydrogen peroxide + (+)-trans-isoalliin
H2O + diethylphosphate → ethanol + H+ + ethylphosphate
(2Z,2E)-2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate + H2O → 2,3-dihydroxybenzoate + 2-oxopent-4-enoate + H+
H2O + sulfinosuccinate → H+ + succinate + sulfite
H2O + an iron chelate + ATP → an iron chelate + phosphate + ADP
H2O + (4R,7S)-7-isopropyl-4-methyloxepan-2-one → H+ + (3R,6S)-6-hydroxy-3,7-dimethyloctanoate
H2O + biochanin A-7-O-glucoside-6''-malonate → malonate + H+ + biochanin A-7-O-glucoside
H2O + (5Z,9E,14Z)-(8ξ,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate → trioxilin A3
H2O + (2R,4S)-2, 4-diaminopentanoate + NAD+ → 2 H+ + ammonia + (2R)-2-amino-4-oxopentanoate + NADH
H2O + 3,6-dihydroxypyridine-2,5-dione → 5-amino-2,4,5-trioxopentanoate + H+
H2O + S-methylglutathione → L-glutamate + S-methyl-L-cysteinylglycine
H2O + 4-deoxy-4-formamido-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate → 4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + formate
H2O + 5-hydroxybenzimidazole ribotide phosphate → (2S,3R,4S,5R)-2-(5-hydroxy-1,3-benzodiazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol + phosphate
H2O + NAD+ + (25R)-3α,7α-dihydroxy-5β-cholestan-26-al → 2 H+ + NADH + (25R)-3α,7α-dihydroxy-5-β-cholestanate
H2O + H+ + dCMP → ammonium + dUMP
H2O + (2Z,4E)-2-amino-6-oxohexa-2,4-dienoate + NAD+ → 2 H+ + NADH + (2Z,4E)-2-aminomuconate
H2O + N-(3-hydroxybutan-2-yl)acetamide → acetate + 3-amino-2-butanol
H2O + L-glutamine + XMP + ATP → 2 H+ + L-glutamate + diphosphate + AMP + GMP
2 H+ + H2O + N-carbamoylputrescine → putrescine + ammonium + CO2
3 ATP + H2O + L-2-aminoadipate + L-valine + L-cysteine → 3 H+ + 3 diphosphate + 3 AMP + N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine
2-phospho-L-ascorbate + H2O → L-ascorbate + phosphate
H2O + triphosphate → diphosphate + phosphate
H2O + [(3S)-4-octanoyl-5-oxooxolan-3-yl]methyl phosphate → 6-dehydro-SCB2 + phosphate
H2O + taxiphyllin → 4-hydroxybenzaldehyde + hydrogen cyanide + β-D-glucopyranose
2 coenzyme A + 2 H2O + 2 NAD+ + 2 oxygen + 10-trans-heptadecenoyl-CoA → 2 hydrogen peroxide + 2 NADH + 2 H+ + 2 acetyl-CoA + 6-trans-tridecenoyl-CoA
H2O + (R)-piperidine-3-carboxamide → (R)-nipecotate + ammonium
2 H2O + pseudooxynicotine + oxygen → methylamine + hydrogen peroxide + 4-oxo-4-(3-pyridyl)-butanoate
H2O + triacetate lactone → triacetate
H2O + NAD(P)+ + 1-propanal → 2 H+ + NAD(P)H + propanoate
H2O + PAI-1-2 → H+ + N-(butyryl)-L-homoserine
H2O + N-acetyl-β-alanine → β-alanine + acetate
H2O + cocaine → methanol + H+ + benzoylecgonine
H2O + geranyl diphosphate → diphosphate + (3S)-linalool
H2O + geranyl diphosphate → diphosphate + (3R)-linalool
H2O + H+ + 6-amino-6-deoxyfutalosine → ammonium + futalosine
H2O + NAD+ + (-)-dehydrodiconiferyl acid aldehyde → 2 H+ + NADH + (-)-dehydrodiconiferyl acid carboxylate
H2O + H+ + 2-iminobutanoate → 2-oxobutanoate + ammonium
H2O + 2-O-(α-D-glucopyranosyl)-sn-glycerol 3-phosphate → 2-O-(α-D-glucopyranosyl)glycerol + phosphate
H2O + N-methyl-L-proline + oxygen → hydrogen peroxide + formaldehyde + L-proline
H2O + dihydroxyacetone + ATP → dihydroxyacetone + phosphate + ADP
H2O + (2Z,4E)-2-hydroxy-5-methyl-6-oxohexa-2,4-dienoate → acetate + H+ + (2Z)-2-hydroxypenta-2,4-dienoate
(+)-copalyl diphosphate + H2O → 13-epi-manool + diphosphate
2 a peptidoglycan dimer (mycobacteria) + 4 H2O → 4 D-alanine + a peptidoglycan with L,D cross-links (mycobacteria) + H+ + mono-trans,octa-cis-decaprenyl diphosphate
H2O + 1-(6-sulfo-α-D-quinovosyl)glycerol → glycerol + 6-sulfo-α-D-quinovose
an oxidized electron donor + H2O + 1-ethyl-4-hydroxybenzene → S-1-(4-hydroxyphenyl)-ethanol + a reduced electron donor
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA ← H2O + 3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA
2 H+ + H2O + ammelide → ammonium + cyanuric acid
an oxidized electron donor + H2O + D-nopaline → a reduced electron donor + 2-oxoglutarate + L-arginine
H2O + H+ + ferric-[N-(2,3-dihydroxybenzoyl)-L-serine trimer] complex → N-(2,3-dihydroxybenzoyl)-L-serine + ferric-[(2,3-dihydroxybenzoylserine)2] complex
H2O + N-acetyl-DL-methionine + ATP → N-acetyl-DL-methionine + H+ + phosphate + ADP
amidinoproclavaminate + H2O → proclavaminate + urea
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione + H2O → H+ + 5-dehydro-2-deoxy-D-gluconate
H2O + aldehydo-D-ribose 5-phosphate → aldehydo-D-ribose + phosphate
2 an oxidized electron donor + 18-hydroxyrenierapurpurin + H2O → 2 a reduced electron donor + χ,χ-caroten-18-oate + H+
H2O + phosphonoacetate → acetate + H+ + phosphate
24-hydroxy-3-oxocholest-4-en-26-oyl-CoA ← H2O + 3-oxocholest-4,24-dien-26-oyl-CoA
H2O + trehalose-cis-keto-mono-mycolate + ATP → H+ + trehalose-cis-keto-mono-mycolate + phosphate + ADP
H2O + dATP → H+ + diphosphate + dAMP
H2O + N-propanoyl-γ-L-glutamyl-L-orornithine-δ-lactam → propanoate + γ-L-glutamyl-L-orornithine-δ-lactam
an oxidized electron donor + H2O + (4E)-2-oxo-hex-4-enoate → a reduced electron donor + (3Z)-4-hydroxy-2-oxohexenoate
H2O + N-acetylphosphinothricin tripeptide → acetate + bialaphos
H2O + 2-pyrone-4,6-dicarboxylate → (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H+
geranyl 6-O-β-D-xylopyranosyl-β-D-glucopyranoside + H2O → primeverose + geraniol
H2O + phenylacetyl-CoA → coenzyme A + phenylacetate + H+
H2O + pyrazinamide → ammonium + pyrazine-2-carboxylate
H2O + 1-O-alkyl-2-acetyl-sn-glycerol → 1-O-alkyl-sn-glycerol + acetate + H+
H2O + 2-O-(α-D-mannosyl)-D-glycerate → (R)-glycerate + α-D-mannopyranose
H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-ω-(methylsulfanyl)pentan-1-imine → L-glutamate + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)pentan-1-imine
H2O + L-phenylalanine + NAD+ → NADH + 3-phenyl-2-oxopropanoate + H+ + ammonium
(S)-3-hydroxybutanoyl-CoA + H2O → coenzyme A + (S)-3-hydroxybutanoate + H+
H2O + (R)-noradrenaline + oxygen → hydrogen peroxide + 3,4-dihydroxyphenylglycolaldehyde + ammonium
H2O + 4-acetamidobutanal + NAD+ → 2 H+ + 4-acetamidobutanoate + NADH
H2O + 9,10-epoxystearate → (9R,10S)-dihydroxystearate
H2O + neoagarohexaose → agaropentaose + 3,6-anhydro-α-L-galactopyranose
coenzyme A + H2O + (E)-4-coumaroyl-CoA + NAD+ → NADH + 4-hydroxybenzoyl-CoA + acetyl-CoA
H2O + H+ + pheophorbide a → methanol + C-132-carboxypyropheophorbide a
H2O + sulfite + oxygen → hydrogen peroxide + sulfate
2,6-dioxo-6-phenylhexa-3-enoate + H2O → 2-oxopent-4-enoate + H+ + benzoate
H2O + (2Z,4Z)-2-hydroxyhepta-2,4-dienedioate → (4S)-4-hydroxy-2-oxoheptanedioate
H2O + D-myo-inositol (1,2) bisphosphate → 1D-myo-inositol 1-monophosphate + phosphate
L-ascorbate 6-phosphate + H2O → 3-keto-L-gulonate 6-phosphate
H2O + 2-hydroxy-6-(2-carboxyphenyl)-6-oxo-2,4-hexadienoate → phthalate + (2E)-2-hydroxypenta-2,4-dienoate + H+
H2O + PAI-1 → H+ + N-(3-oxododecanoyl)-L-homoserine
H2O + (1S,4R)-2,4,5-trichloro-2,5-cyclohexadiene-1-diol → (1S,4S)-2,5-dichloro-2,5-cyclohexadiene-1,4-diol + H+ + chloride
thiamine + H2O → 4-amino-2-methyl-5-pyrimidinemethanol + H+ + 5-(2-hydroxyethyl)-4-methylthiazole
H2O + cytidine-3'-monophosphate → cytidine + phosphate
H2O + L-ornithine + ATP → L-ornithine + H+ + phosphate + ADP
H2O + mono-trans,octa-cis-decaprenyl diphosphate → H+ + phosphate + trans,octacis-decaprenyl phosphate
H2O + (2Z,2E)-2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate → salicylate + 2-oxopent-4-enoate + H+
H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine → pyruvate + (E)-ω-(methylsulfanyl)butyl-thiohydroximate + ammonium
H2O + N-acetyl-D-muramate 6-phosphate → N-acetylmuramate + phosphate
H2O + α-maltose 6'-phosphate → maltose + phosphate
H2O + spermidine + oxygen → hydrogen peroxide + propane-1,3-diamine + 4-aminobutanal
H2O + glycyl-L-methionine → glycine + L-methionine
H2O + S-adenosyl-L-methionine + 12-ethyl-8-propylbacteriochlorophyllide c → H+ + 5'-deoxyadenosine + L-methionine + 12-ethyl-71-hydroxy-8-propylbacteriochlorophyllide c
H2O + 2,4,6-trioxoheptanoate → acetate + acetylpyruvate + H+
H2O + ethylphosphate → ethanol + phosphate
H2O + dAMP → phosphate + 2'-deoxyadenosine
H2O + L-glyceraldehyde 3-phosphate → L-glyceraldehyde + phosphate
coenzyme A + H2O + ATP → coenzyme A + phosphate + ADP
N-(aminomethyl)urea + H2O → N-(hydroxymethyl)urea + ammonium
H2O + (+)-bornyl-diphosphate → diphosphate + (+)-borneol
H2O + (2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one → (2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran
H2O + 2'-deoxyuridine 3'-monophosphate → 2'-deoxyuridine + phosphate
4-deoxy-2-O-sulfo-β-L-erythro-hex-4-enopyranuronosyl-(1,4)-D-N-sulfoglucosamine 6-O-sulfate + H2O → 4-deoxy-β-L-erythro-hex-4-enopyranuronosyl-(1,4)-D-N-sulfoglucosamine 6-O-sulfate + H+ + sulfate
H2O + tetrathionate → H+ + sulfate + thiosulfate + S0
H2O + β-hexachlorocyclohexane → 2,3,4,5,6-pentachlorocyclohexanol + H+ + chloride
H2O + L-dehydro-ascorbate → dehydroascorbate (bicyclic form)
H2O + 3-(methylsulfanyl)acryloyl-CoA → 3-hydroxy-3-(methylsulfanyl)propanoyl-CoA
H2O + phosphorylated MMF1 butenolide intermediate → MMF1 butenolide intermediate + phosphate
3 H2O + enterobactin → 3 N-(2,3-dihydroxybenzoyl)-L-serine + 3 H+
H2O + p-nitrophenyl-α-L-arabinofuranoside → 4-nitrophenol + α-L-arabinofuranose + H+
H2O + α-D-ribose 1-(acetamidomethylphosphonate) 5-triphosphate → α-D-ribose-1-(2-N-acetamidomethylphosphonate) 5-phosphate + H+ + diphosphate
H2O + decanal + NAD+ → 2 H+ + NADH + decanoate
H2O + 3-oxopropanoyl-CoA → coenzyme A + H+ + 3-oxopropanoate
H2O + γ-L-glutamyl-[(S)-allyl]-L-cysteine → S-allyl-L-cysteine + L-glutamate
H2O + ATP + urea + CO2 → 2 H+ + urea-1-carboxylate + phosphate + ADP
H2O + 1-(2-acetamido-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol → acetate + 1-(2-amino-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol
H2O + 2-ketocyclohexane-1-carbonyl-CoA → pimeloyl-CoA + H+
H2O + H+ + adenine → ammonium + hypoxanthine
H2O + Coα-[α-(5-methylbenzimidazolyl)]-Coβ-adenosylcobamide 5'-phosphate → Coα-[α-(5-methylbenzimidazolyl)]-Coβ-adenosylcobamide + phosphate
H2O + oxaloacetate 4-methyl ester → methanol + H+ + oxaloacetate
H2O + 1D-myo-inositol 4-monophosphate → myo-inositol + phosphate
H2O + 1D-myo-inositol 6-monophosphate → myo-inositol + phosphate
H2O + 3-O-aceylpapaveroxine → acetate + H+ + narcotine hemiacetal
H2O + 1D-myo-inositol 5-monophosphate → myo-inositol + phosphate
H2O + (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate → H+ + fumarate + (2Z)-2-hydroxypenta-2,4-dienoate
H2O + L-asparagine → ammonium + L-aspartate
H2O + 1D-myo-inositol 2-monophosphate → myo-inositol + phosphate
H2O + adenosine 3'-monophosphate → adenosine + phosphate
H2O + a methyl group + ATP → a methyl group + phosphate + ADP
H2O + 1D-myo-inositol 1-monophosphate → myo-inositol + phosphate
H2O + 1D-myo-inositol 3-monophosphate → myo-inositol + phosphate
H2O + oxygen + N6-methyl-L-lysine → hydrogen peroxide + formaldehyde + L-lysine
H2O + dUDP → H+ + phosphate + dUMP
H2O + furan-2,5-dicarbaldehyde → 5-(dihydroxymethyl)furan-2-carbaldehyde
H2O + 3-deoxy-D-glycero-D-galacto-nononate 9-phosphate → 2-keto-3-deoxy-D-glycero-D-galacto-nononate + phosphate
12-ethyl-8-isobutylbacteriochlorophyllide d ← H2O + 12-ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d
H2O + trans-2,3-epoxysuccinate → meso-tartrate
H2O + 2'-N-acetylparomamine → acetate + paromamine
H2O + 4-(γ-L-glutamylamino)butanal + NAD(P)+ → 2 H+ + NAD(P)H + 4-(γ-L-glutamylamino)butanoate
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)pentan-1-imine → L-seryl-glycine + (E)-ω-(methylsulfanyl)pentyl-thiohydroximate
H2O + (Z)-1-(L-cysteinyglycin-S-yl)-N-hydroxy-2-phenylethan-1-imine → glycine + (Z)-1-(L-cystein-S-yl)-N-hydroxy-2-phenylethan-1-imine
H2O + (4Z)-2-oxohept-4-enedioate → (4S)-4-hydroxy-2-oxoheptanedioate
H2O + NAD+ + (S)-lactaldehyde → 2 H+ + NADH + (S)-lactate
arbutin-6-phosphate + H2O → β-D-glucose 6-phosphate + hydroquinone
(13E)-labda-7,13-dien-15-yl diphosphate + H2O → (13E)-labda-7,13-dien-15-ol + diphosphate
H2O + 3-deoxy-D-manno-octulosonate 8-phosphate → 3-deoxy-α-D-manno-2-octulosonate + phosphate
(S)-2-amino-6-oxohexanoate + H2O + NAD(P)+ → 2 H+ + NAD(P)H + L-2-aminoadipate
H2O + decanoyl-CoA → coenzyme A + decanoate + H+
an oxidized electron donor + H2O + L-sorbosone 2,6-lactone → a reduced electron donor + 2-keto-L-gulonate + H+
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethan-1-imine → glycine + (E)-1-(L-cystein-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethan-1-imine
H2O + spermine + ATP → spermine + phosphate + ADP
tributyrin + H2O → 1,2-dibutyrin + butanoate + H+
H2O + trans-cinnamate → 3-hydroxy-3-phenylpropanoate
H2O + S-fenclorimyl-L-cysteine → pyruvate + ammonium + 6-chloro-2-phenyl-4-sulfanylpyrimidine
H2O + D-erythro-D-gluco-octose α-1,8-bisphosphate → phosphate + D-erythro-D-gluco-octose α-1-phosphate
H2O + 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoate → (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + catechol + H+
H2O + a thiol group + ATP → a thiol group + phosphate + ADP
H2O + α-D-glucopyranose 1-phosphate → phosphate + β-D-glucopyranose
H2O + deoxylimonate → deoxylimononic acid D-ring-lactone + H+
H2O + rutin → H+ + β-L-rhamnopyranose + quercetin-3-glucoside
H2O + D-glycero-β-D-manno-heptose 1,7-bisphosphate → D-glycero-β-D-manno-heptose 1-phosphate + phosphate
H2O + L-valine + ATP → L-valine + phosphate + ADP
H2O + N-(2,3-dihydroxybenzoyl)-L-serine trimer → N-(2,3-dihydroxybenzoyl)-L-serine + N-(2,3-dihydroxybenzoyl)-L-serine dimer + H+
2,6-dioxo-6-phenylhexa-3-enoate + H2O → H+ + (2Z)-2-hydroxypenta-2,4-dienoate + benzoate
an oxidized electron donor + H2O + isoquinoline → isoquinolin-2(1H)-one + a reduced electron donor
H2O + glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose → glycoprotein-phospho-D-mannose + H+ + N-acetyl-β-D-glucosamine
H2O + 4-methylbenzaldehyde + NAD+ → 2 H+ + NADH + 4-methylbenzoate
coenzyme A + H2O + cyclohexane-1-carboxylate + ATP → 2 phosphate + cyclohexane-1-carbonyl-CoA + H+ + AMP
H2O + adenylylcoelenterazine disulfonate + oxygen → 2 H+ + coelenterazine disulfonate dioxetanone + AMP
H2O + geranyl diphosphate → diphosphate + (-)-endo-fenchol
H2O + neolinustatin → lotaustralin + β-D-glucopyranose
2 juglone + 2 H2O → 2 3,5-dihydroxy-1,4-naphthoquinol
H2O + propanoyl-CoA + glyoxylate → coenzyme A + (2R,3S)-3-methylmalate + H+
H2O + dADP → H+ + phosphate + dAMP
H2O + geranyl diphosphate → diphosphate + geraniol
22-hydroxy-3-oxochol-4-en-24-oyl-CoA ← H2O + 3-oxochol-4,22-dien-24-oyl-CoA
H2O + N-acetylphenylethylamine → acetate + 2-phenylethylamine
H2O + ethanolamine + oxygen → hydrogen peroxide + glycolaldehyde + ammonium
H2O + (2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoate + NAD+ → 2 H+ + 2-maleylacetate + NADH
H2O + 3'-ketosucrose → 3-dehydro-D-glucopyranose + β-D-fructofuranose
H2O + catechol + ATP → catechol + phosphate + ADP
D-xylono-1,4-lactone 5-phosphate + H2O → 5-phospho-D-xylonate + H+
H2O + methylmercury-S-glutatione → L-glutamate + S-(methylmercury)-L-cysteinylglycine
(1,4)-β-xylobiose + H2O + ATP → (1,4)-β-xylobiose + phosphate + ADP
H2O + pyridoxamine + oxygen → hydrogen peroxide + pyridoxal + ammonium
H2O + a reduced electron donor + ATP + 3-devinyl-3-(1-hydroxyethyl)chlorophyllide a → an oxidized electron donor + phosphate + ADP + 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a
H2O + O-phospho-L-tyrosine → L-tyrosine + phosphate
H2O + sucrose 6F-phosphate → β-D-glucose 6-phosphate + β-D-fructofuranose
H2O + N-acetyl-L-citrulline → acetate + L-citrulline
H2O + hypoxanthine → 2 H+ + xanthine
H2O + acibenzolar-S-methyl → methanol + acibenzolar
an oxidized electron donor + H2O + 4-methylphenol → 4-hydroxybenzyl alcohol + a reduced electron donor
2 S-adenosyl-L-methionine + H2O + (31R)-8,12-diethylbacteriochlorophyllide c → 2 H+ + 2 5'-deoxyadenosine + 2 L-methionine + (31R)-8,12-diethylbacteriochlorophyllide e
H2O + P1,P4-bis(5'-guanosyl) tetraphosphate → 2 H+ + GTP + GMP
H2O + (2R)-2-chloro-2,5-dihydro-5-oxofuran-2-acetate → 2 H+ + HCl + 2-maleylacetate
H2O + L-proline + ATP → L-proline + phosphate + ADP
H2O + N2-succinylglutamate → L-glutamate + succinate
H2O + (Z)-1-(L-cysteinyglycin-S-yl)-N-hydroxy-2-phenylethan-1-imine → L-seryl-glycine + H+ + (Z)-2-phenyl-1-thioacetohydroximate
3 coenzyme A + an oxidized electron donor + H2O + Δ2,5-3,4,4-trimethylpimeloyl-CoA + H+ → 3 acetyl-CoA + a reduced electron donor + isobutanoyl-CoA
H2O + N-acetyl-D-galactosamine 6-phosphate → acetate + D-galactosamine-6-phosphate
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione + H2O → 5-deoxy-D-glucuronate + H+
H2O + (2Z,4Z)-2-amino-5-chloro-6-oxohexa-2,4-dienoate + NAD+ → 2 H+ + NADH + (2Z,4Z)-2-amino-5-chlorohexa-2,4-dienedioate
H2O + 4-sulfomuconolactone → 2 H+ + 2-maleylacetate + sulfite
H2O + D-myo-inositol (2,4) bisphosphate → 1D-myo-inositol 2-monophosphate + phosphate
H2O + N-(γ-L-glutamyl)-L-alaninol → L-alaninol + L-glutamate
H2O + 6-O-trans-methoxy-mycolyl-trehalose 6-phosphate → trehalose-trans-methoxy-mono-mycolate + phosphate
H2O + S-methyl-L-methionine → L-homoserine + H+ + dimethyl sulfide
H2O + nitrite + ATP → phosphate + nitrite + ADP
H2O + geranylgeranyl diphosphate → (13E)-labda-7,13-dien-15-ol + diphosphate
an oxidized electron donor + H2O + 6-hydroxypseudooxynicotine → a reduced electron donor + 2,6-dihydroxypseudooxynicotine
H2O + L-canavanine → L-canaline + H+ + urea
H2O + 5-phospho-α-D-ribose 1,2-cyclic phosphate → α-D-ribose 1,5-bisphosphate + H+
2 oxygen + H2O + choline → 2 hydrogen peroxide + glycine betaine + H+
H2O + (2E,6E)-farnesyl diphosphate → 10-epi-cubebol + diphosphate
H2O + anserine → β-alanine + Nπ-methyl-L-histidine
H2O + cocaine → H+ + benzoate + ecgonine methyl ester
H2O + β-nicotinamide D-ribonucleotide → nicotinamide + H+ + aldehydo-D-ribose 5-phosphate
thymidine 3'-monophosphate + H2O → thymidine + phosphate
H2O + betaine aldehyde + oxygen → glycine betaine + hydrogen peroxide + H+
violaxanthin + H2O + NADP+ → antheraxanthin + NADPH + oxygen
H2O + 8-amino-8-demethylriboflavin 5'-phosphate → 8-amino-8-demethylriboflavin + phosphate
2 S-adenosyl-L-methionine + H2O + 12-ethyl-8-propylbacteriochlorophyllide c → 2 H+ + 2 5'-deoxyadenosine + 2 L-methionine + 12-ethyl-8-propylbacteriochlorophyllide e
H2O + Coα-[α-(5-hydroxybenzimidazolyl)]-Coβ-adenosylcobamide 5'-phosphate → Coα-[α-(5-hydroxybenzimidazolyl)]-Coβ-adenosylcobamide + phosphate
H2O + L-carnitinamide → L-carnitine + ammonium
H2O + thyrotropin releasing hormone → 5-oxo-L-proline + L-histidyl-L-prolylamide
H2O + adenosine + H+ → inosine + ammonium
3 H2O + 3 S0 → 2 H+ + 2 hydrogen sulfide + sulfite
H2O + all-trans-retinal + oxygen → hydrogen peroxide + all-trans-retinoate + H+
H2O + N-(4-aminobenzoyl)-L-glutamate → L-glutamate + 4-aminobenzoate
an oxidized electron donor + H2O + N6-dimethylallyladenine → a reduced electron donor + trans-zeatin
H2O + S-sulfinatoglutathione → H+ + glutathione + sulfite
an oxidized electron donor + coenzyme A + H2O + (3-methylphenyl)itaconyl-CoA → 3-methylbenzoyl-CoA + a reduced electron donor + succinyl-CoA
H2O + H+ + AMP → ammonium + IMP
H2O + N-Formyl-L-kynurenine → formate + L-kynurenine + H+
2-hydroxyisobutyramide ← H2O + 2-hydroxy-2-methylpropanenitrile
H2O + S-(5-hydroxypentan-3-yl)-L-cysteine → pyruvate + ammonium + 3-sulfanylpentan-1-ol
S-ethyl-L-cysteine + H2O → pyruvate + ethanethiol + ammonium
H2O + (2Z,4E)-4-hydroxy-6-oxohexa-2,4-dienoate + NAD+ → 2 H+ + 2-maleylacetate + NADH
H2O + paraoxon → 2 H+ + diethylphosphate + 4-nitrophenol
2 phosphate + 2 ADP + an oxidized ferredoxin [iron-sulfur] cluster + chlorophyllide a ← 2 H2O + 2 ATP + a reduced ferredoxin [iron-sulfur] cluster + protochlorophyllide a
H2O + isotrichotriol → trichotriol
H2O + β-D-cellobiose 6'-phosphate → β-D-glucose 6-phosphate + β-D-glucopyranose
H2O + α-D-ribose-1-[N-(phosphonomethyl)glycine] 5-triphosphate → α-D-ribose-1-[N-(phosphonomethyl)glycine] 5-phosphate + H+ + diphosphate
H2O + (2S)-2-acetamido-4-aminobutanoate → acetate + L-2,4-diaminobutanoate
H2O + toluene + ATP → phosphate + toluene + ADP
H2O + L-leucyl-arginomycin → arginomycin + L-leucine
H2O + Nω-hydroxy-L-arginine → hydroxyurea + L-ornithine
H2O + L-2-amino-4-chloropent-4-enoate → 2-oxopent-4-enoate + H+ + ammonium + chloride
H2O + 4-hydroxy-2-nonenal-N-acetyl-L-cysteine → acetate + S-(4-hydroxy-nonenal-3-yl)-L-cysteine
H2O + (2E,6E)-farnesyl diphosphate → (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate
H2O + oxygen + D-aspartate → hydrogen peroxide + ammonium + oxaloacetate
H2O + (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate → formate + H+ + (2Z)-2-hydroxypenta-2,4-dienoate
H2O + XMP → xanthosine + phosphate
H2O + N-acetylputrescine + oxygen → hydrogen peroxide + 4-acetamidobutanal + ammonium
H2O + 4-hydroxybenzaldehyde + NADP+ → 2 H+ + NADPH + 4-hydroxybenzoate
H2O + 2-oxo-3-(phosphooxy)propyl 7-methyl-3-oxooctanoate → 3-hydroxy-2-oxopropyl 7-methyl-3-oxooctanoate + phosphate
H2O + DIMBOA-β-D-glucoside → H+ + β-D-glucopyranose + DIMBOA
H2O + geranylfarnesyl diphosphate → ophiobolin F + diphosphate
H2O + NAD(P)+ + 3,6-anhydro-α-L-galactopyranose → 2 H+ + NAD(P)H + 3,6-anhydro-L-galactonate
H2O + propionamide → propanoate + ammonium
2 ATP + H2O + ammonium + CO2 → 2 ADP + 3 H+ + carbamoyl phosphate + phosphate
H2O + ATP + pyrimidine → phosphate + ADP + pyrimidine
H2O + γ-L-glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide → L-glutamate + S-(hercyn-2-yl)-L-cysteine S-oxide
H2O + (Z)-3-ureidoacrylate peracid → (Z)-3-peroxyaminoacrylate + H+ + carbamate
H2O + L-saccharopine + oxygen → (S)-2-amino-6-oxohexanoate + hydrogen peroxide + L-glutamate
H2O + phosphonoformaldehyde + NADP+ → NADPH + H+ + phosphonoformate
H2O + phytenal + NAD+ → 2 H+ + phytenate + NADH
H2O + (2E,6E)-farnesyl diphosphate → drimenol + diphosphate
H2O + (Z)-1-(glutathion-S-yl)-N-hydroxy-2-phenylethan-1-imine → L-glutamate + (Z)-1-(L-cysteinyglycin-S-yl)-N-hydroxy-2-phenylethan-1-imine
phosphoenolpyruvate + H2O → pyruvate + phosphate
H2O + cis-3,4-dehydroadipyl-CoA semialdehyde + NADP+ → 2 H+ + NADPH + cis-3,4-dehydroadipyl-CoA
H2O + ectoine → (2S)-2-acetamido-4-aminobutanoate
H2O + vinyl acetate → allyl alcohol + formate
H2O + α-D-galactofuranose + ATP → α-D-galactofuranose + H+ + phosphate + ADP
H2O + lovastatin lactone → lovastatin acid + H+
H2O + (glutathion-S-yl)(1H-indol-3-yl)acetonitrile → L-glutamate + (L-cysteinylglycin-S-yl)(1H-indol-3-yl)acetonitrile
H2O + S-(4-hydroxy-3-methylbutan-2-yl)-L-cysteinylglycine → glycine + S-(4-hydroxy-3-methylbutan-2-yl)-L-cysteine
H2O + glycerol 2-phosphate → glycerol + phosphate
H2O + isobutyl acetate → acetate + isobutanol + H+
H2O + citraconate → (2R,3S)-3-methylmalate
2 H2O + N-(2,3-dihydroxybenzoyl)-L-serine trimer → 2 H+ + 3 N-(2,3-dihydroxybenzoyl)-L-serine
H2O + cysteamine S-phosphate → cysteamine + phosphate
Pb2+ + H2O + ATP → Pb2+ + phosphate + ADP
an oxidized electron donor + H2O + uracil → 2 H+ + a reduced electron donor + barbiturate
H2O + D-myo-inositol (2,4,5) trisphosphate → D-myo-inositol (2,5) bisphosphate + phosphate
H2O + NAD(P)+ + L-2-aminopropionaldehyde → 2 H+ + NAD(P)H + L-alanine
an oxidized electron donor + H2O + iminodiacetate → glycine + a reduced electron donor + glyoxylate
H2O + NAD+ + (indol-3-yl)acetaldehyde → 2 H+ + NADH + (indol-3-yl)acetate
Nω-phosphocreatine + H2O → creatine + phosphate
H2O + D-myo-inositol (1,3,4)-trisphosphate → D-myo-inositol (3,4)-bisphosphate + phosphate
2 H+ + H2O + 3-(carbamoylamino)-2-methylpropanoate → (R)-3-amino-2-methylpropanoate + ammonium + CO2
H2O + (4-hydroxyphenyl)acetaldehyde + NAD+ → 2 H+ + (4-hydroxyphenyl)acetate + NADH
H2O + 1-heptanal + oxygen → hydrogen peroxide + heptanoate + H+
H2O + 2-arachidonoylglycerol → glycerol + H+ + arachidonate
H2O + 1,6,8-trimethylallantoate → N-methylurea + N,N'-dimethylurea + glyoxylate
H2O + L-leucyl-blasticidin S → blasticidin S + L-leucine
H2O + cis-stilbene oxide → (1R,2R)-1,2-diphenylethane-1,2-diol
H2O + S-sulfanylglutathione + oxygen → 2 H+ + glutathione + sulfite
H2O + arsenate + ATP → phosphate + arsenate + ADP
H2O + (11Z,14Z,17Z)-icosatrienoyl-CoA → (11Z,14Z,17Z)-icosa-11,14,17-trienoate + coenzyme A + H+
6-oxocamphor + H2O → H+ + [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetate
H2O + 7,8-dihydroneopterin 3'-triphosphate → 2 H+ + acetaldehyde + 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate
H2O + S-adenosyl-L-methionine + 12-ethyl-8-isobutylbacteriochlorophyllide c → H+ + 5'-deoxyadenosine + L-methionine + 12-ethyl-71-hydroxy-8-isobutylbacteriochlorophyllide c
10 malonyl-CoA + 9 H+ + H2O → 10 coenzyme A + 10 CO2 + 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate
2 NAD+ + H2O + histidinol → 2 NADH + 3 H+ + L-histidine
12 a reduced ferredoxin [iron-sulfur] cluster + 40 H2O + 40 ATP + N2 → 12 an oxidized ferredoxin [iron-sulfur] cluster + 2 ammonia + 28 H+ + 3 H2 + 40 phosphate + 40 ADP
H2O + butachlor → butoxymethanol + 2-chloro-N-(2,6-diethylphenyl)acetamide
H2O + oxygen + 3-aci-nitropropanoate → hydrogen peroxide + H+ + 3-oxopropanoate + nitrite
H2O + (R)-4'-phosphopantothenoyl-L-cysteine + H+ → (R)-4'-phosphopantothenate + cysteamine + CO2
Ca2+ + H2O + ATP → Ca2+ + H+ + phosphate + ADP
H2O + monomethyl sulfate → methanol + H+ + sulfate
H2O + allantoate + ATP → phosphate + allantoate + ADP
H2O + aldehydo-D-xylose + NAD+ → 2 H+ + NADH + D-xylonate
OH-DDVA meta-cleavage product + H2O → 5-carboxyvanillate + 4-carboxy-2-hydroxypenta-2,4-dienoate + H+
H2O + 2-hydroxy-7-methyl-6-oxo-2,4-octadienoate → isobutanoate + H+ + (2Z)-2-hydroxypenta-2,4-dienoate
H2O + L-glutamate + oxygen → hydrogen peroxide + 2-oxoglutarate + ammonium
H2O + IDP → H+ + phosphate + IMP
H2O + α,α-trehalose 6-phosphate → phosphate + α,α-trehalose
H2O + pheophytin a → phytol + H+ + pheophorbide a
H2O + guanosine 2',3'-cyclic monophosphate → H+ + guanosine 2'-monophosphate
an oxidized electron donor + deoxyshikonin + H2O → a reduced electron donor + shikonin
H2O + guanosine 2',3'-cyclic monophosphate → H+ + guanosine 3'-monophosphate
H2O + daidzin → daidzein + β-D-glucopyranose
H2O + 4-pyridoxolactone → 4-pyridoxate + H+
H2O + 3-sulfino-L-alanine → H+ + L-alanine + sulfite
H2O + 2-chloro-N-(2,6-diethylphenyl)acetamide → 2-chloroacetate + H+ + 2,6-diethylaniline
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + avermitilol
H2O + methyl (indol-3-yl)acetate → methanol + H+ + (indol-3-yl)acetate
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + (+)-corvol ether A
H2O + cellotetraose → 2 β-D-cellobiose
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + 8-epi-cedrol
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + β-eudesmol
H2O + D-myo-inositol (1,2) bisphosphate → 1D-myo-inositol 2-monophosphate + phosphate
H2O + 3-(4-hydroxyphenyl)pyruvate + acetyl-CoA → coenzyme A + 2-(4-hydroxybenzyl)-malate + H+
H2O + sucrose 6G-phosphate → β-D-glucose 6-phosphate + β-D-fructofuranose
H2O + H+ + N-cyclopropylmelamine → ammonium + N-cyclopropylammeline
H2O + isochorismate → (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate
H2O + phosphorylated MMF4 butenolide intermediate → MMF4 butenolide intermediate + phosphate
an oxidized electron donor + O-carbamoyl-deacetylcephalosporin C + H2O → 7-α-hydroxy-O-carbamoyl-deacetylcephalosporin C + a reduced electron donor
H2O + α,α-trehalose → β-D-glucopyranose + α-D-glucopyranose
3 H2O + GTP → 2 H+ + 2 phosphate + 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
H2O + 4-O-methylrhodomycinone D → methanol + H+ + 10-carboxy-13-deoxydaunorubicin
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + (+)-isoafricanol
H2O + UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + D-alanine
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)heptan-1-imine → glycine + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)heptan-1-imine
H2O + taurine + ATP → taurine + phosphate + ADP
H2O + 3-α(S)-strictosidine → CO2 + strictosamide
an oxidized electron donor + H2O + prostaglandin-H2 → prostaglandin G2 + a reduced electron donor
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + intermedeol
H2O + (R)-piperazine-2-tert-butylcarboxamide → tert-butylamine + (R)-piperazine-2-carboxylate
2 H2O + 2 hydrogen peroxide + 4 Mn2+ + oxygen → 4 MnIVO2 + 8 H+
H2O + 2-protocatechuoylphloroglucinolcarboxylate → protocatechuate + phloroglucinol carboxylate + H+
H2O + GTP → 7,8-dihydroneopterin 2',3'-cyclic phosphate + formate + H+ + diphosphate
H2O + N1,N12-diacetylspermine + oxygen → hydrogen peroxide + 3-acetamidopropanal + N1-acetylspermidine
2 H2O + dichlorocarbene → 2 chloride + 3 H+ + formate
H2O + UDP-N-acetyl-α-D-muramoyl-L-alanyl-L-glutamate + ATP → H+ + diphosphate + UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate + AMP
H2O + neral → sulcatone + acetaldehyde
H2O + 5-formyl-tetrahydromethanopterin → tetrahydromethanopterin + formate + H+
H2O + cytidine 2'-monophosphate → cytidine + phosphate
H2O + cis-zeatin riboside monophosphate → cis-zeatin riboside + phosphate
H2O + geranylgeranyl diphosphate → geranylgeraniol + diphosphate
2 coenzyme A + 2 H2O + 2 NAD+ + 2 oxygen + oleoyl-CoA → 2 hydrogen peroxide + 2 NADH + 2 H+ + 2 acetyl-CoA + (5Z)-tetradecenoyl-CoA
H2O + NAD+ + phosphonate → NADH + H+ + phosphate
2 H2O + 3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine → 2 glycine + 3-benzyl-3,6 -bis(cysteinyl)- 6-(hydroxymethyl)-diketopiperazine
H2O + 4-coumaroylacetyl-CoA + trans-feruloyl-CoA → 2 coenzyme A + demethoxycurcumin + CO2
H2O + S-methyl-3-phospho-1-thio-D-glycerate → S-methyl-1-thio-D-glycerate + phosphate
H2O + trans-zeatin riboside triphosphate → 2 H+ + trans-zeatin riboside diphosphate + phosphate
H2O + NAD(P)+ + 3,6-anhydro-L-galactofuranose → 2 H+ + NAD(P)H + 3,6-anhydro-L-galactonate
cyclohexane-1,2-dione + H2O → 6-oxohexanoate + H+
acetylene + H2O → acetaldehyde
H2O + triglucosyl-enterobactin → triglucosyl-(2,3-dihydroxybenzoylserine)3 + H+
(R)-3-hydroxyoctanoyl-CoA ← H2O + (2E)-oct-2-enoyl-CoA
H2O + L-lysine + oxygen → hydrogen peroxide + 6-amino-2-oxohexanoate + ammonium
H2O + D-glycero-α-D-manno-heptose 1,7-bisphosphate → D-glycero-α-D-manno-heptose 1-phosphate + phosphate
coenzyme A + H+ + trihomocitrate ← H2O + 2-oxopimelate + acetyl-CoA
H2O + L-proline betaine + ATP → L-proline betaine + phosphate + ADP
H2O + 4-amino-2-methyl-5-pyrimidinemethanol + ATP → 4-amino-2-methyl-5-pyrimidinemethanol + phosphate + ADP
H2O + pyruvate + acetyl-CoA → coenzyme A + H+ + (R)-citramalate
H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)pentan-1-imine → pyruvate + (E)-ω-(methylsulfanyl)pentyl-thiohydroximate + ammonium
H2O + dalpatein 7-O-β-D-apiofuranosyl-(1->6)-β-D-glucopyranoside → β-D-apiofuranosyl-(1->6)-D-glucose + dalpatein
(S)-3-hydroxytetradecanoyl-CoA ← H2O + 2E)-tetradec-2-enoyl-CoA
phosphoenolpyruvate + H2O + 2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose → pseudaminate + phosphate
peregrinol diphosphate ← H2O + geranylgeranyl diphosphate
H2O + NAD+ + (25S)-26-oxocholest-4-en-3-one → 2 H+ + NADH + (25S)-3-oxocholest-4-en-26-oate
H2O + (2Z,2E)-2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate → salicylate + H+ + (2Z)-2-hydroxypenta-2,4-dienoate
2 decanoyl-CoA + H2O → 2 coenzyme A + (2R)-2-octyl-3-oxododecanoate + H+
H2O + ATP + benzoate → phosphate + ADP + benzoate
H2O + {[4-({1-[5-(4-methoxyphenyl)-1,3,4-oxadiazole-2-carbonyl]azetidin-3-yl}oxy)phenyl]methyl}(methyl)[(3-methyloxetan-3-yl)methyl]amine → 2-[({[4-({1-[5-(4-methoxyphenyl)-1,3,4-oxadiazole-2-yl}oxy)phenyl]methyl}(methyl)amino)methyl]-2-methylpropane-1,3-diol
H2O + D-myo-inositol (2,3,4) trisphosphate → D-myo-inositol (2,4) bisphosphate + phosphate
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)octan-1-imine → glycine + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)octan-1-imine
2 H2O + 2-(hydroxymethyl)-3-(acetamidomethylene)succinate + H+ → acetate + 2-hydroxymethyl-4-oxobutanoate + ammonium + CO2
H2O + dCTP → H+ + diphosphate + dCMP
3-hydroxy-4-methyl-L-kynurenine + H2O → 3-hydroxy-4-methylanthranilate + H+ + L-alanine
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O → 1-palmitoyl-sn-glycero-3-phosphocholine + palmitate + H+
H2O + cadaverine + oxygen → hydrogen peroxide + 5-aminopentanal + ammonium
H2O + N1-acetyl-N2-formyl-5-methoxykynuramine → formate + H+ + N-acetyl-5-methoxykynurenamine
H2O + 3'-amino-3'-deoxyAMP → phosphate + 3'-amino-3'-deoxyadenosine
H2O + S-allyl-L-cysteine + oxygen → hydrogen peroxide + alliin
H2O + butanoyl-CoA + glyoxylate → coenzyme A + H+ + 3-ethylmalate
N-methylputrescine + H2O + oxygen → hydrogen peroxide + N-methylaminobutanal + ammonium
H2O + oxygen + S0 → 2 H+ + sulfite
(S)-4-hydroxy-2-oxopentanoate ← H2O + (2Z)-2-hydroxypenta-2,4-dienoate
H2O + L,L-homocystine + ATP → L,L-homocystine + H+ + phosphate + ADP
H2O + 4-(γ-L-glutamylamino)butanoate → 4-aminobutanoate + L-glutamate
H2O + acetylpyruvate → acetate + pyruvate + H+
H2O + UTP → UMP + H+ + diphosphate
H2O + L-glutamine + ATP + cob(II)yrinate c-monoamide → H+ + L-glutamate + phosphate + ADP + cob(II)yrinate a,c-diamide
Hg2+ + H2O + ATP → Hg2+ + phosphate + ADP
H2O + trans-feruloyl-CoA + feruloylacetyl-CoA → 2 coenzyme A + curcumin + CO2
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + 10-epi-γ-eudesmol
H2O + (1R,6S)-dihydroxycyclohexa-2,4-diene-1,4-dicarboxylate + NAD+ → protocatechuate + NADH + H+ + hydrogencarbonate
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + (+)-(1(10)E,4E,6S,7R)-germacradien-6-ol
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + 10-epi-juneol
3 H+ + 3 malonyl-CoA + H2O + acetyl-CoA → 3 CO2 + 4 coenzyme A + H2O + orsellinate + H+
H2O + 4-O-acetyl-UDP-N-acetylglucosamine → 4-O-acetyl-N-acetylmannosamine + H+ + UDP
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + (+)-(2S,3R,9R)-pristinol
H2O + all-trans-retinal + NAD+ → 2 H+ + NADH + all-trans-retinoate
9α-copalyl diphosphate + H2O → 13S-vitexifolin A + diphosphate
2 H2O + 2-oxepin-2(3H)-ylideneacetyl-CoA + NADP+ → 2 H+ + 3-oxo-5,6-didehydrosuberyl-CoA + NADPH
H2O + ADP-5-ethyl-4-methylthiazole-2-carboxylate → H+ + 4-methyl-5-(2-phosphooxyethyl)thiazole + AMP + CO2
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + (+)-corvol ether B
H2O + H+ + N-cyclopropylammeline → ammonium + N-cyclopropylammelide
H2O + diethylthiophosphate → diethylphosphate + hydrogen sulfide
2-O-(4-deoxy-β-L-threo-hex-4-enopyranuronosyl)-α-L-rhamnopyranose + H2O → (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + α-L-rhamnopyranose
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + (+)-epicubenol
H2O + dITP → H+ + diphosphate + dIMP
H2O + p-nitrophenyl-α-L-rhamnopyranoside → 4-nitrophenol + H+ + β-L-rhamnopyranose
maltotetraose + H2O → maltotriose + β-D-glucopyranose
2 H+ + N-carbamoylsarcosine + H2O → sarcosine + ammonium + CO2
H2O + 4-hydroxybenzaldehyde + NAD(P)+ → 2 H+ + NAD(P)H + 4-hydroxybenzoate
H2O + NADP+ + L-isoleucine → ammonia + NADPH + (S)-3-methyl-2-oxopentanoate
adenosine pentaphosphate + H2O → adenosine tetraphosphate + H+ + phosphate
H2O + dioleoyl phosphatidate → oleate + H+ + 1-oleoyl-sn-glycerol 3-phosphate
H2O + NAD+ + 1,10-dihydro-1,10-dihydroxyfluoren-9-one → 2 H+ + NADH + 3-2-carboxyphenylcatechol
H2O + H+ + oxygen + 5-methoxytryptamine → hydrogen peroxide + ammonium + 5-methoxyindoleacetaldehyde
(+)-copalyl diphosphate + H2O → ent-16-a-hydroxy-kaurene + diphosphate
H2O + UDP → UMP + H+ + phosphate
H2O + S-(4-hydroxy-2-methylpentan-2-yl)-L-cysteinylglycine → glycine + S-(4-hydroxy-2-methylpentan-2-yl)-L-cysteine
2 octanoyl-CoA + H2O → 2 coenzyme A + (2R)-2-hexyl-3-oxodecanoate + H+
(12Z,15Z)-9,10-epoxyoctadeca-12,15-dienoate + H2O → (12Z,15Z)-9,10-dihydroxyoctadeca-12,15-dienoate
H2O + L-saccharopine + NAD+ → NADH + 2-oxoglutarate + H+ + L-lysine
3-oxopropanoate ← H2O + propynoate
2 H+ + H2O + Fe3+-[salmochelin S2] complex → N-(2,3-dihydroxybenzoyl)-L-serine + H+ + Fe3+-[diglucosyl-(2,3-dihydroxybenzoylserine)2] complex
H2O + dTTP → H+ + phosphate + dTDP
H2O + phloretin → phloretate + phloroglucinol + H+
H2O + 5,6-α-epoxy-5-α-cholestan-3-β-ol → cholestane-3-β-5-α,6-β-triol
H2O + yersiniabactin + ATP → yersiniabactin + phosphate + ADP
H2O + ATP → H+ + diphosphate + AMP
β-D-galactopyranosyl-(1→3)-D-galactopyranose + H2O → bacillithiol + H+ + (R)-lactate
H2O + (S)-azetidine-2-carboxylate → 2-hydroxy-4-aminobutanoate
2-chloro-trans-dienelactone + H2O → 2-chloromaleylacetate + H+
8-oxo-dADP + H2O → 8-oxo-dAMP + H+ + phosphate
an oxidized electron donor + H2O + 4-oxo-4-(3-pyridyl)-butanoate → 6-hydroxy-3-succinoyl-pyridine + a reduced electron donor
H2O + S-adenosyl-L-methionine + 3-[(1-carboxyvinyl)oxy]benzoate → H+ + L-methionine + hydrogencarbonate + 6-amino-6-deoxyfutalosine
H2O + protoheme + (2E,6E)-farnesyl diphosphate → heme o + diphosphate
H2O + NAD(P)+ + (indol-3-yl)acetaldehyde → 2 H+ + NAD(P)H + (indol-3-yl)acetate
Zn2+ + H2O + ATP → Zn2+ + phosphate + ADP
H2O + D-glucono-1,5-lactone → D-gluconate + H+
H2O + S-adenosyl-L-methionine + magnesium-protoporphyrin IX 13-monomethyl ester → H+ + 5'-deoxyadenosine + L-methionine + 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester
H2O + 3,4-dihydroxyphenylacetyl-CoA → coenzyme A + 3,4-dihydroxyphenylacetate + H+
H2O + (S)-2-O-sulfonatolactate → H+ + (S)-lactate + sulfate
H2O + tungstate + ATP → phosphate + tungstate + ADP
H2O + bis(2-ethylhexyl)phthalate → 2-ethylhexyl phthalate + H+ + 2-ethylhexan-1-ol
H2O + creatinine + H+ → N-methylhydantoin + ammonium
7,8-epoxy-17S-hydroxy-docosahexaenoate + H2O → resolvin D2
7,8-epoxy-17S-hydroxy-docosahexaenoate + H2O → resolvin D1
16 H2O + 16 ATP + 8 a reduced ferredoxin [iron-sulfur] cluster + N2 → 16 phosphate + 16 ADP + 2 ammonium + 6 H+ + 8 an oxidized ferredoxin [iron-sulfur] cluster + H2
H2O + octadecanal → formate + H+ + heptadecane
H2O + lotaustralin → (2R)-2-hydroxy-2-methylbutanenitrile + β-D-glucopyranose
H2O + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + NAD+ → NADH + 2-oxoglutarate + L-2,3-diaminopropanoate + H+
H2O + S-(4-oxo-2-methylpentan-2-yl)-L-cysteine → 4-methyl-4-sulfanylpentan-2-one + pyruvate + ammonium
H2O + 2-oxosuccinamate → ammonium + oxaloacetate
H2O + 2-isocapryloyl-3S-(phosphooxy)methyl-γ-butyrolactone phosphate → 2-isocapryloyl-3R-hydroxymethyl-γ-butyrolactone + phosphate
H2O + 2,4-didehydro-3-deoxy-L-rhamnonate → pyruvate + H+ + (S)-lactate
H2O + (R)-S-lactoylglutathione → H+ + glutathione + (R)-lactate
H2O + S-formylmycothiol → formate + mycothiol + H+
2 H2O + fumonisin B1 → 2 H+ + 2 propane-1,2,3-tricarboxylate + aminopentol
2 coenzyme A + 2 H2O + 2 NAD+ + 2 oxygen + 10-cis-heptadecenoyl-CoA → 2 hydrogen peroxide + 2 NADH + 2 H+ + 2 acetyl-CoA + 6-cis-tridecenoyl-CoA
H2O + 2,6-dihydroxypseudooxynicotine → 4-methylaminobutanoate + 2,6-dihydroxypyridine + H+
H2O + L-glutamine → ammonium + L-glutamate
H2O + pyruvate + ubiquinone-6 → acetate + ubiquinol-6 + CO2
H2O + cyclic- 3,4-O-oxalyl-L-threonate → 4-O-oxalyl-L-threonate + H+
H2O + 13-sophorosyloxydocosanoate 6',6''-diacetate → acetate + 13-[O(2')-β-D-glucopyranosyl-β-D-glucopyranosyloxy]docosanoate O(6'')-acetate + H+
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + (2E,6E)-hedycaryol
H2O + dTDP → H+ + phosphate + dTMP
H2O + salmochelin S4 → salmochelin S2 + H+
H2O + acetyl-CoA → coenzyme A + acetate + H+
2 NAD+ + H2O + UDP-α-D-glucose → 2 NADH + 3 H+ + UDP-α-D-glucuronate
H2O + intermediate III → intermediate IV
H2O + 5,10-methenyltetrahydromethanopterin → 10-formyl-tetrahydromethanopterin + H+
melibiose + H2O + ATP → melibiose + phosphate + ADP
H2O + ATP + Fe3+ → phosphate + ADP + Fe3+
2 H2O + 2 H+ + N2-succinyl-L-arginine → 2 ammonium + N2-succinyl-L-ornithine + CO2
an oxidized electron donor + H2O + 8-demethyl-8-formylriboflavin 5'-phosphate → a reduced electron donor + 8-carboxy-8-demethylriboflavin 5'-phosphate + H+
H2O + iron(III) dicitrate + ATP → phosphate + iron(III) dicitrate + ADP
H2O + β-ketoisocaproate → acetate + isobutanoate + H+
sn-glycero-3-phosphocholine + H2O → choline + H+ + sn-glycerol 3-phosphate
H2O + indol-3-ylmethylisothiocyanate-glutathione → glycine + indol-3-ylmethylisothiocyanate-[γ-Glu-Cys}
FAD + H2O + N6-dimethylallyladenine + H+ → FADH2 + 3-methyl-2-butenal + adenine
H2O + D-glyceraldehyde 3-phosphate → phosphate + D-glyceraldehyde
H2O + S-prenyl-L-cysteine + oxygen → hydrogen peroxide + 3-methyl-2-butenal + L-cysteine
(S)-3-hydroxy-(5Z)-dodecenoyl-CoA ← H2O + (2E,5Z)-dodecenoyl-CoA
2 an oxidized electron donor + 2 H2O + 8',8-diapocarotene-8',8-dial → 2 a reduced electron donor + 2 H+ + crocetin
H2O + aldehydo-D-galacturonate + NAD+ → 2 H+ + NADH + D-galactarate
H2O + Nα-[(2E)-3-methylhex-2-enoyl]-L-glutamine → (2E)-3-methylhex-2-enoate + L-glutamine
H2O + urate + oxygen → (S)-5-hydroxyisourate + hydrogen peroxide
H2O + D-Glucose + ATP → D-Glucose + phosphate + ADP
H2O + 7,8-dihydroneopterin 2',3'-cyclic phosphate → 7,8-dihydroneopterin 2'-phosphate + H+
H2O + H+ + Fe3+-[salmochelin S2] complex → salmochelin SX + Fe3+-[salmochelin S1] complex
H2O + (2E,6E)-farnesyl diphosphate → (+)-τ-muurolol + diphosphate
hesperidin + H2O → (2S)-hesperetin + rutinose + H+
H2O + 7,8-dihydroneopterin 2',3'-cyclic phosphate → 7,8-dihydroneopterin 3'-phosphate + H+
H2O + 12α-hydroxy-3-oxochol-4-en-24-oyl-CoA → coenzyme A + H+ + 12-α-hydroxy-3 oxochol-4-enoate
H2O + 5'-O-phosphonoadenylyl-(3'→5')-adenosine → 2 AMP + H+
H2O + streptomycin 6-phosphate → streptomycin + phosphate
nicotinate + H2O + NADP+ → 6-hydroxynicotinate + NADPH + H+
an oxidized electron donor + H2O + D-octopine → a reduced electron donor + pyruvate + L-arginine
2 H2O + H+ + (Z)-phenylacetaldehyde oxime → hydrogen peroxide + phenylacetaldehyde + ammonium
Cu2+ + H2O + ATP → Cu2+ + H+ + phosphate + ADP
H2O + D-myo-inositol (1,2,4,5,6)-pentakisphosphate → D-myo-inositol (1,2,5,6) tetrakisphosphate + phosphate
H2O + spermidine + oxygen → hydrogen peroxide + 3-aminopropanal + putrescine
FAD + H2O → 2 H+ + FMN + AMP
H2O + L-djenkolate + ATP → L-djenkolate + H+ + phosphate + ADP
2-chloroacrylate + H2O → 2-chloro-2-hydroxypropanoate
H2O + syringaldehyde + NAD+ → 2 H+ + syringate + NADH
3-dehydro scyllo-inosose + H2O → 5-dehydro-L-gluconate + H+
phosphoenolpyruvate + H2O + 2,4-diacetamido-2,4,6-trideoxy-α-D-mannopyranose → 5,7-diacetamido-3,5,7,9-tetradeoxy-D-glycero-D-galacto-nonulopyranosonate + phosphate
H2O + D-alanyl-D-alanine + ATP → D-alanyl-D-alanine + phosphate + ADP
H2O + 2-deoxy-D-glucose 6-phosphate → 2-deoxy-D-glucose + phosphate
H2O + phosphite + ATP → phosphite + phosphate + ADP
H2O + ADP → H+ + phosphate + AMP
H2O + 8-oxo-dGDP → H+ + phosphate + 8-oxo-dGMP
H2O + L-histidinol phosphate → histidinol + phosphate
H2O + Hg0 + ATP → phosphate + Hg0 + ADP
myristoylated pyoverdine intermediate + H2O → pyoverdine biosynthetic intermediate + myristate + H+
H2O + 3-hydroxypropanoyl-CoA → coenzyme A + 3-hydroxypropanoate + H+
H2O + glycyl-L-glutamine → glycine + L-glutamine
H2O + sarcosine + oxygen → methylamine + hydrogen peroxide + glyoxylate
2 Fe2+ + 4 H2O + oxygen → 2 [FeO(OH)] monomer + 4 H+ + hydrogen peroxide
H2O + S-(1-hydroxyhexan-3-yl)-L-cysteine → pyruvate + ammonium + 3-sulfanylhexan-1-ol
(S)-3-hydroxy-isobutanoyl-CoA + H2O → coenzyme A + H+ + (S)-3-hydroxy-isobutanoate
2 an oxidized electron donor + 2 H2O + acetyl-CoA → 2 a reduced electron donor + coenzyme A + glyoxylate + H+
2 H2O + CDP-glycerol → 2 H+ + cytidine + phosphate + sn-glycerol 3-phosphate
H2O + UDP-α-D-kanosamine → H+ + UDP + kanosamine
H2O + 4-carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate → (1Z,3Z)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate + methanol + H+
H2O + 3-oxo-myristoyl-CoA → coenzyme A + H+ + 3-oxo-myristate
an oxidized electron donor + nicotinate + H2O → 6-hydroxynicotinate + a reduced electron donor
4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl--D-galactosamine 6-sulfate + H2O → 4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + H+ + sulfate
4-deoxy-β-D-gluc-4-enuronosyl-2-sulfate-(1,3)-N-acetyl-β-D-galactosamine + H2O → N-acetyl-α-D-galactosamine + 5-dehydro-4-deoxy-2-O-sulfo-D-glucuronate
H2O + versiconol acetate → acetate + versiconol
cefoperazone + H2O + ATP → cefoperazone + H+ + phosphate + ADP
H2O + neocarratetraose 4-O-disulfate → neocarratetraose 4-O-sulfate + H+ + sulfate
H2O + (Z)-2-methylureidoacrylate peracid → (Z)-2-methyl-peroxyaminoacrylate + H+ + carbamate
H2O + H+ + (Z)-2-methylureidoacrylate peracid → (Z)-2-methyl-peroxyaminoacrylate + ammonium + CO2
5-chlorocarbonyl-4-hydroxy-penta-2,4-dienate + H2O → 2-maleylacetate + H+ + chloride
H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-2-(4-hydroxyphenyl)ethan-1-imine → L-glutamate + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-2-(4-hydroxyphenyl)ethan-1-imine
H2O + 4(5)-epoxy-17S-hydroxy-docosahexaenoate → resolvin D4
H2O + 2-oxoethyl-CoM + NAD+ → 2 H+ + NADH + 2-carboxyethyl-CoM
H2O + 4(5)-epoxy-17S-hydroxy-docosahexaenoate → resolvin D3
nicotinamide + H2O → nicotinate + ammonium
H2O + H+ + N-carbobenzyloxy-L-glutamine → benzyl alcohol + L-glutamine + CO2
H2O + dGTP → H+ + diphosphate + dGMP
H2O + O-phospho-L-homoserine → L-threonine + phosphate
H2O + dCDP → H+ + phosphate + dCMP
H2O + 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA → 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxylate + acetyl-CoA
(13E)-8α-hydroxylabd-13-en-15-yl diphosphate + H2O + a reduced electron donor → an oxidized electron donor + labd-13-en-8α-,15 diol + diphosphate
H2O + 6-(methylsulfanyl)-2-oxohexanoate + acetyl-CoA → coenzyme A + 2-[(4'-methylsulfanyl)butyl]malate + H+
H2O + benzo[a]pyrene-4,5-oxide → (4R,5R)-benzo[a]pyrene-trans-4,5-dihydrodiol
H2O + NADP+ + D-glyceraldehyde 3-phosphate → 2 H+ + NADPH + 3-phospho-D-glycerate
H2O + geranylgeranyl diphosphate → hydropyrenol + diphosphate
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + (-)-patchoulol
H2O + (2S)-2-amino-4-deoxy-chorismate → pyruvate + (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylate
H2O + S-adenosyl-L-methionine + precorrin-5 → acetate + S-adenosyl-L-homocysteine + precorrin-6A + H+
H2O + prenyl diphosphate → prenol + diphosphate
2 H2O + (3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate + NADH → NAD+ + erythro-4-hydroxy-L-glutamate
acrylamide + H2O → acrylate + ammonium
H2O + NAD(P)+ + 2,5-diaminohexanoate → NAD(P)H + 2-amino-5-oxohexanoate + H+ + ammonium
2 H2O + E-2-(acetamidomethylidene)succinate + H+ → acetate + succinate semialdehyde + ammonium + CO2
2 NAD+ + GDP-α-D-mannose + H2O → 2 NADH + 3 H+ + GDP-α-D-mannuronate
xanthine + H2O + oxygen → hydrogen peroxide + urate
H2O + S-adenosyl-L-methionine + (31R)-8,12-diethyl-71-hydroxybacteriochlorophyllide c → H+ + 5'-deoxyadenosine + L-methionine + (31R)-8,12-diethyl-71,71-dihydroxybacteriochlorophyllide c
dammarenediol II ← H2O + (3S)-2,3-epoxy-2,3-dihydrosqualene
H2O + 4-sulfophenyl acetate → acetate + 4-sulfophenol + H+
an oxidized electron donor + H2O + 4-guanidinobutyraldehyde → 4-guanidinobutanoate + a reduced electron donor + H+
isoprimeverose + H2O → α-D-xylopyranose + β-D-glucopyranose
N7-methylguanosine 5'-phosphate + H2O → N7-methylguanosine + phosphate
H2O + tomatidine galactoside → tomatidine + β-D-galactopyranose
H2O + 6-O-cis-keto-mycolyl-trehalose 6-phosphate → trehalose-cis-keto-mono-mycolate + phosphate
H2O + N-isopropylammelide + H+ → isopropylamine + cyanuric acid
H2O + N-(2,3-dihydroxybenzoyl)-L-serine dimer → 2 N-(2,3-dihydroxybenzoyl)-L-serine + H+
H2O + 4-(phosphooxy)pentanoyl-CoA → 3-hydroxy-pentanoyl-CoA + phosphate
H2O + iminodiacetate → 2 H+ + glycine + glyoxylate
H2O + (E)-4-coumaroyl-CoA + feruloylacetyl-CoA → 2 coenzyme A + demethoxycurcumin + CO2
2 ATP + H2O + acetophenone + hydrogencarbonate → 2 H+ + 2 phosphate + 2 ADP + 3-oxo-3-phenylpropanoate
H2O + 2-[(2'-methylsulfanyl)propyl]maleate → 3-[(3'-methylsulfanyl)propyl]malate
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)octan-1-imine → L-seryl-glycine + (E)-ω-(methylsulfanyl)octyl-thiohydroximate
H2O + (S)-ureidoglycine → ammonium + (S)-ureidoglycolate
trans-permethrin + H2O → (3-phenoxyphenyl)methanol + (1S,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxlate + H+
H2O + MMF2 butenolide intermediate → H2O + methylenomycin furan 2
2 H2O + limonin → 2 H+ + limonoate
H2O + (3E,5Z)-tetradeca-3,5-dienoyl-CoA → coenzyme A + (3E,5Z)-tetradecadienoate + H+
H2O + H+ + (2Z,4E)-2-amino-5-methyl-muconate → (E)-5-methyl-2-oxo-3-hex-3-enedioate + ammonium
2 H2O + a peptidoglycan dimer (meso-diaminopimelate containing) → 2 D-alanine + di-trans,octa-cis-undecaprenyl diphosphate + a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)
an oxidized electron donor + H2O + 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate → an oxidized electron donor + 3-hydroxy-2-methylpyridine-4,5-dicarboxylate + a reduced electron donor + H+
H2O + 4-O-oxalyl-L-threonate → L-threonate + H+ + oxalate
H2O + 2-oxo-3-(5-oxofuran-2-ylidene)propanoate → H+ + 3-maleylpyruvate
2-hydroxy-dATP + H2O → 2-hydroxy-dAMP + H+ + diphosphate
H2O + testololactone → testolate + H+
H2O + oleoyl-CoA → coenzyme A + oleate + H+
H2O + atropine → tropine + tropate + H+
H2O + 2-carboxy-L-xylonolactone → 2-carboxy-L-threo-pentonate + H+
H2O + 2-hydroxy-2-methylpropanal + NAD+ → 2 H+ + NADH + 2-hydroxy-2-methylpropanoate
H2O + cis-coumarinic acid-β-D-glucoside → coumarinate + β-D-glucopyranose
H2O + 1-18:1-2-18:1-phosphatidylethanolamine → oleate + H+ + 1-(oleoyl)-sn-glycero-3-phosphoethanolamine
H2O + 2-nitroimidazole → H+ + 1,3-dihydro-2H-imidazol-2-one + nitrite
H2O + adenosine 5'-phosphosulfate → sulfate + AMP
5-chlorocarbonyl-2-hydroxy-penta-2,4-dienate + H2O → 2 H+ + (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + chloride
all-trans-lycopene + H2O + prenyl diphosphate → dihydroisopentenyldehydrorhodopin + diphosphate
H2O + β-D-fructose 2,6-bisphosphate → β-D-fructofuranose 6-phosphate + phosphate
3 H2O + H+ + ferric-enterobactin complex → 2 N-(2,3-dihydroxybenzoyl)-L-serine + Fe3+-[N-(2,3-dihydroxybenzoyl)-L-serine] complex
H2O + α-maltose → 2 α-D-glucopyranose
H2O + 4-oxoglutaramate → 2-oxoglutarate + ammonium
H2O + S-formylbacillithiol → bacillithiol + formate + H+
H2O + 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl 1-phosphate → 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate
H2O + 4-[(2-hydroxyethoxy)carbonyl]benzoate → terephthalate + ethylene glycol + H+
H2O + di-trans, poly-cis-polyprenyl diphosphate (C80) → di-trans, poly-cis-polyprenol (C80) + diphosphate
H2O + geranial → sulcatone + acetaldehyde
H2O + sn-glycerol 1-phosphate → glycerol + phosphate
H2O + 2-hydroxyisobutyramide → 2-hydroxy-2-methylpropanoate + ammonium
sucrose + H2O + ATP → sucrose + phosphate + ADP
H2O + L-alanyl-glycine → glycine + L-alanine
H2O + β-nicotinamide D-ribonucleotide → 1-(β-D ribofuranosyl)nicotinamide + phosphate
H2O + PAI-1 → 3-oxo-dodecanoate + L-homoserine lactone
H2O + glucotropaeolin → 2-benzyl-thiohydroximate-O-sulfate + H+ + β-D-glucopyranose
H2O + scopolin → scopoletin + β-D-glucopyranose
H2O + S-benzyl-L-cysteinylglycine → glycine + S-benzyl-L-cysteine
H2O + toyocamycin phosphate → phosphate + toyocamycin
4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H2O → 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + H+ + phosphate
H2O + geranyl diphosphate → sabinene hydrate + diphosphate
H2O + cyclohexane-1-carbonyl-CoA → coenzyme A + cyclohexane-1-carboxylate + H+
H2O + (2E)-5-methylhexa-2,4-dienoyl-CoA → 3-hydroxy-5-methylhex-4-enoyl-CoA
H2O + L-tyrosine + oxygen → ammonia + hydrogen peroxide + (4-hydroxyphenyl)acetaldehyde + CO2
H2O + (2E,4E)-2-amino-5-chloro-6-oxohexa-2,4-dienoate + NAD+ → 2 H+ + (2E,4E)-2-amino-5-chlorohexa-2,4-dienedioate + NADH
H2O + N8-acetylspermidine + oxygen → hydrogen peroxide + propane-1,3-diamine + 4-acetamidobutanal
H2O + MMF5 butenolide intermediate → H2O + methylenomycin furan 5
5-chloro-trans-dienelactone + H2O → 5-chloromaleylacetate + H+
H2O + 8-oxo-GDP → H+ + phosphate + 8-oxo-GMP
D-sedoheptulose 1,7-bisphosphate + H2O → D-sedoheptulose 7-phosphate + phosphate
H2O + acetaldehyde + oxygen → acetate + hydrogen peroxide + H+
H2O + (9S,10S)-10-hydroxy-9-(phosphooxy) octadecanoate → (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate
H2O + 5,6-β-epoxy-5-β-cholestan-3-β-ol → cholestane-3-β-5-α,6-β-triol
H2O + NAD+ + (3S,5S)-3,5-diaminohexanoate → NADH + (S)-5-amino-3-oxohexanoate + H+ + ammonium
H2O + oxygen + 2-phenylethylamine → hydrogen peroxide + phenylacetaldehyde + ammonium
H2O + L-leucine + ATP → L-leucine + phosphate + ADP
H2O + parathion → 2 H+ + diethylthiophosphate + 4-nitrophenol
H2O + S-(6-hydroxy-4-methylhexan-4-yl)-L-cysteine → pyruvate + ammonium + 3-methyl-3-sulfanylhexan-1-ol
H2O + N-β-D-glucosyl-(indol-3-yl)acetyl-L-aspartate → L-aspartate + N-β-D-glucosyl-(indol-3-yl)acetate
H2O + oxythiamine → H+ + 5-(2-hydroxyethyl)-4-methylthiazole + 5-(hydroxymethyl)-2-methyl-4(1H)-pyrimidinone
H2O + oxygen + 3-sulfocatechol → 3 H+ + (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + sulfite
H2O + L-alanyl-γ-D-glutamyl-meso-diaminopimelate → L-alanyl-D-glutamate + meso-diaminopimelate
H2O + (Z)-N,N'-(but-2-ene-2,3-diyl)diacetamide → N-(3-oxobutan-2-yl)acetamide + acetamide
H2O + S-methylglutathione → glycine + γ-L-glutamyl-(S)-methyl-L-cysteine
H2O + fluoroacetaldehyde + NAD+ → 2 H+ + fluoroacetate + NADH
β-tabtoxin + H2O → tabtoxinine-β-lactam + L-threonine
H2O + L-4-hydroxyphenylglycine-L-arginyl-D-4-hydroxyphenylglycine-L-seryl-L 4-hydroxyphenylglycine → L-4-hydroxyphenylglycine-L-arginine + D-4-hydroxyphenylglycine-L-seryl-L 4-hydroxyphenylglycine
H2O + 4-imidazolone-5-propanoate + a reduced electron donor + oxygen → an oxidized electron donor + 4-oxoglutaramate + formate + ammonium
H2O + 5-methylcytosine + H+ → thymine + ammonium
H2O + 6-O-trans-keto-mycolyl-trehalose 6-phosphate → trehalose-trans-keto-mono-mycolate + phosphate
sucrose + H2O → α-D-glucopyranose + β-D-fructofuranose
H2O + 2,3-diphospho-D-glycerate → phosphate + 2-phospho-D-glycerate
H2O + oxygen + tryptamine → hydrogen peroxide + ammonium + (indol-3-yl)acetaldehyde
H2O + 2,3-diphospho-D-glycerate → phosphate + 3-phospho-D-glycerate
H2O + NADH → (R)-NADHX
H2O + NADH → (S)-NADHX
H2O + 3-hydroxy-4-methyl-D-kynurenine → 3-hydroxy-4-methylanthranilate + H+ + L-alanine
H2O + L-glutamine + ATP → L-glutamine + phosphate + ADP
salicin 6-phosphate + H2O → salicyl alcohol + β-D-glucose 6-phosphate
H2O + maltose + ATP → maltose + phosphate + ADP
H2O + dopamine + oxygen → hydrogen peroxide + 3,4-dihydroxyphenylacetaldehyde + ammonium
5-chloro-4-hydroxy-2-oxopentanoate ← H2O + (3E)-5-chloro-2-oxopent-3-enoate
2 H2O + GTP → 2 H+ + 2 phosphate + GMP
H2O + ATP + adenosylcobinamide → phosphate + ADP + adenosylcobinamide
H2O + (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA → coenzyme A + L-2-acetamido-6-oxoheptanedioate
H2O + 3,4-dihydroxyphenylglycolaldehyde + NAD+ → 2 H+ + NADH + 3,4-dihydroxymandelate
an oxidized electron donor + H2O + (+)-pinoresinol → a reduced electron donor + (+)-6-hydroxypinoresinol
H2O + 3-hydroxypropanal + NAD(P)+ → 2 H+ + NAD(P)H + 3-hydroxypropanoate
H2O + 8-oxo-GTP → H+ + diphosphate + 8-oxo-GMP
H2O + autoinducer 2 + ATP → autoinducer 2 + phosphate + ADP
H2O + L-cystine + ATP → L-cystine + phosphate + ADP
H2O + histidinal + NAD+ → 2 H+ + NADH + L-histidine
H2O + L-methionine-(R)-S-oxide + ATP → L-methionine-(R)-S-oxide + H+ + phosphate + ADP
H2O + (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate → 2-oxopent-4-enoate + H+ + succinate
2 H2O + urate + oxygen → hydrogen peroxide + CO2 + (S)-(+)-allantoin
H2O + (2E)-2-methyl-4,6-dioxohept-2-enedioate → citraconate + pyruvate + H+
H2O + protoheme + ATP → H+ + phosphate + protoheme + ADP
(31R)-8,12-diethylbacteriochlorophyllide d ← H2O + 8,12-diethyl-3-vinylbacteriochlorophyllide d
(+)-copalyl diphosphate + H2O → nezukol + diphosphate
2 an oxidized ferredoxin [iron-sulfur] cluster + 2 phosphate + 2 ADP + chlorophyllide a ← 2 H2O + 2 a reduced ferredoxin [iron-sulfur] cluster + 2 ATP + protochlorophyllide a
H2O + angiotensin I → L-histidyl-L-leucine + angiotensin II
H2O + all-trans-retinyl palmitate → all-trans-retinol + palmitate + H+
H2O + formamide → formate + ammonium
H2O + luteolin 7-O-[β-D-glucosyluronate-(1,2)-β-D-glucosiduronate]-4'-O-β-D-glucosiduronate → luteolin 7-O-β-D-diglucuronide + β-D-glucuronate
H2O + phytate → phosphate + 1D-myo-inositol (1,2,3,4,6)-pentakisphosphate
H2O + phytate → phosphate + D-myo-inositol (1,2,4,5,6)-pentakisphosphate
H2O + phytate → phosphate + D-myo-inositol 1,3,4,5,6-pentakisphosphate
H2O + phytate → phosphate + D-myo-inositol (1,2,3,4,5)-pentakisphosphate
H2O + phytate → phosphate + D-myo-inositol (1,2,3,5,6) pentakisphosphate
H2O + N6,N6-dimethyl-L-arginine → L-citrulline + dimethylamine
H2O + D-myo-inositol 1,2-cyclic phosphate → 1D-myo-inositol 1-monophosphate + H+
2 H2O + D-glucurono-6,3-lactone + NAD+ → 3 H+ + NADH + D-glucarate
H2O + (indol-3-yl)acetyl-L-leucine → L-leucine + (indol-3-yl)acetate
an oxidized electron donor + H2O + 5-methoxyindoleacetaldehyde → a reduced electron donor + 5-methoxyindole acetate
2 a peptidoglycan dimer (E. faecium, tetrapeptide) + 3 H2O → 4 D-alanine + a peptidoglycan tetramer with an L,D cross-link (Enterococcus faecium) + di-trans,octa-cis-undecaprenyl diphosphate + H+
H2O + carbamoyl phosphate + kanamycin B + ATP → H+ + diphosphate + phosphate + 6''-O-carbamoylkanamycin B + AMP
H2O + XTP → H+ + phosphate + XDP
2 H2O + 2,3-epoxy-2,3-dihydrobenzoyl-CoA → formate + cis-3,4-dehydroadipyl-CoA semialdehyde + H+
H2O + allantoate → (S)-ureidoglycolate + urea
an oxidized electron donor + H2O + phosphonoformaldehyde → a reduced electron donor + phosphonoformate
2 H2O + dUTP → 2 H+ + 2 phosphate + dUMP
H2O + H+ + 2-iminosuccinate → ammonium + oxaloacetate
H2O + cyclic di-3',5'-adenylate → H+ + 5'-O-phosphonoadenylyl-(3'→5')-adenosine
H2O + (glutathion-S-yl)-bimane → glycine + (γ-glutamylcysteine-S-yl)-bimane
H2O + geranylgeranyl diphosphate → aphidicolan-16β-ol + diphosphate
H2O + methyl parathion → 2 H+ + 4-nitrophenol + dimethylthiophosphate
H2O + creatinine + a reduced electron donor → an oxidized electron donor + acetate + methylguanidinium
H2O + hydroxyatrazine + H+ → isopropylamine + N-ethylammelide
H2O + AZD1979 → M1
H2O + Fe3+-[diglucosyl-enterobactin] complex → H+ + Fe3+-[salmochelin S2] complex
H2O + H+ + O-ureido-D-serine + ATP → ammonium + phosphate + D-cycloserine + ADP + CO2
tuberculosinyl diphosphate + H2O → (13S)-isotuberculosinol + diphosphate
H2O + 7,8-dihydroneopterin 3'-triphosphate → 7,8-dihydroneopterin 3'-phosphate + H+ + diphosphate
creatine + H2O → sarcosine + urea
H2O + choline sulfate + ATP → choline sulfate + H+ + phosphate + ADP
acetylcholine + H2O → acetate + choline + H+
H2O + D-myo-inositol (1,4)-bisphosphate → 1D-myo-inositol 4-monophosphate + phosphate
H2O + 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon → 2,5,6-trihydroxy-3-methylpyridine + 2-oxobut-3-enanoate
H2O + (2E,6E)-farnesyl diphosphate → presilphiperfolan-8β-ol + diphosphate
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + 7-epi-α-eudesmol
H2O + linuron → 3,4-dichloroaniline + N,O-dimethylhydroxylamine + CO2
H2O + 1-[18-hydroxyoeoyl]-2-[18-hydroxy-lioleoyl]-sn-glycerol 3-phosphate → 1-[18-hydroxyoeoyl]-2-[18-hydroxy-linoleoyl]-sn-glycerol + phosphate
H2O + polyethylene terephthalate → polyethylene terephthalate + 4-[(2-hydroxyethoxy)carbonyl]benzoate
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + α-eudesmol
H2O + dichloromethane → 2 H+ + 2 chloride + formaldehyde
H2O + O-phosphoethanolamine → ethanolamine + phosphate
H2O + imidazole acetaldehyde + NAD+ → 2 H+ + 4-imidazoleacetate + NADH
2 H2O + (glutathion-S-yl)-4-methoxy-3-indolylmethylisothiocyanate → raphanusamate + glycine + L-glutamate + 4-methoxy-3-indolylmethylamine
H2O + (2Z,4Z)-2-amino-5-formylhexa-2,4-dienedioate + H+ → (2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde + ammonium
2 H2O + ATP → 2 H+ + 2 phosphate + AMP
H2O + (S)-malyl N-acetyl-α-D-glucosaminide → acetate + (S)-malyl α-D-glucosaminide
H2O + NADPH + magnesium-protoporphyrin IX 13-monomethyl ester → 3 H+ + NADP+ + 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester
H2O + carbamoyl phosphate + ATP → (O-carbamoyl)adenylate + diphosphate + phosphate
H2O + formylaminopyrimidine → formate + aminomethylpyrimidine
H2O + choline sulfate → choline + H+ + sulfate
H2O + (2S)-2-amino-5-iminopentanoate + H+ → L-glutamate-5-semialdehyde + ammonium
H2O + L-cysteine → L-serine + hydrogen sulfide
H2O + cyclohexane-1,3-dione → 5-oxohexanoate + H+
an oxidized electron donor + phosphate + ADP + 3-deacetyl-3-vinylbacteriochlorophyllide a ← H2O + a reduced electron donor + ATP + chlorophyllide a
an oxidized electron donor + H2O + 2-phenylethylamine → a reduced electron donor + phenylacetaldehyde + ammonium
H2O + bacillibactin + ATP → bacillibactin + phosphate + ADP
H2O + β-nicotinamide D-ribonucleotide → β-nicotinate D-ribonucleotide + ammonium
trans-dienelactone + H2O → 2-maleylacetate + H+
5-hydroxy-CTP + H2O → 5-hydroxy-CMP + H+ + diphosphate
H2O + L-glutamine + ATP + UTP → 2 H+ + L-glutamate + phosphate + ADP + CTP
12-ethyl-8-propylbacteriochlorophyllide d ← H2O + 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d
H2O + β-L-galactose 1-phosphate → β-L-galactopyranose + phosphate
H2O + dCMP → 2'-deoxycytidine + phosphate
H2O + 4-hydroxybenzoate 1-phenylethylidene → H+ + acetophenone hydrazone + 4-hydroxybenzoate
H2O + dimethylsulfoniopropanoate-amine + oxygen → hydrogen peroxide + ammonium + 3-dimethylsulfoniopropionaldehyde
H2O + L-lysine + ATP → H+ + L-lysine + phosphate + ADP
D-galactono-1,4-lactone + H2O → D-galactonate + H+
apo-4'-lycopenal + H2O + NAD(P)+ → NADPH + H+ + apo-4'-lycopenoate
H2O + N5-phospho-L-glutamine → phosphoramidate + H+ + L-glutamate
2 S-adenosyl-L-methionine + H2O + 12-ethyl-8-isobutylbacteriochlorophyllide c → 2 H+ + 2 5'-deoxyadenosine + 2 L-methionine + 12-ethyl-8-isobutylbacteriochlorophyllide e
5-chloro-5-deoxyribose 1-phosphate + H2O → 5-chloro-5-deoxy-D-ribose + phosphate
ppGpp + H2O → H+ + diphosphate + GDP
2 an oxidized electron donor + H2O + dimethylsulfonio-2-hydroxybutanoate → 2 a reduced electron donor + dimethylsulfoniopropanoate + CO2
H2O + L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine → L-alanyl-γ-D-glutamyl-meso-diaminopimelate + D-alanine
H2O + 12α-hydroxy-3-oxochol-4,6-dien-24-oyl-CoA → coenzyme A + 12-α-hydroxy-3 oxochola-4,6-dienoate + H+
H2O + (2E,6E)-farnesyl diphosphate → (2E,6E)-farnesol + diphosphate
H2O + histamine + oxygen → imidazole acetaldehyde + hydrogen peroxide + ammonium
H2O + malonyldaidzin → malonate + H+ + daidzin
H2O + H+ + 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one → 5-amino-6-(5-phospho-D-ribitylamino)uracil + ammonium
H2O + D-myo-inositol (2,3,4,5) tetrakisphosphate → D-myo-inositol (2,4,5) trisphosphate + phosphate
H2O + oxygen + desoxyhemigossypol-6-methyl ether → hydrogen peroxide + hemigossypol-6-methyl ether
H2O + 3-sulfino-L-alanine + NAD+ → L-cysteate + NADH + H+
H2O + 4-aminoimidazole → 3,5-dihydro-4H-imidazol-4-one + H+ + ammonium
H2O + Coα-[α-(adenin-9-yl)]-Coβ-adenosylcobamide 5'-phosphate → Coα-[α-(adenin-7-yl)]-Coβ-adenosylcobamide + phosphate
2 H2O + 3-phenylpropionitrile → 3-phenylpropanoate + ammonium
H2O + (2E,7Z)-hexadecenoyl-CoA → (S)-3-hydroxy-(7Z)-hexadecenoyl-CoA
H2O + S-formylglutathione → formate + H+ + glutathione
H2O + unsaturated gellan tetrasaccharide → 4-deoxy-L-threo-hex-4-enopyranuronate + β-D-Glcp-(1→4)-α-L-Rhap-(1→3)-D-Glcp
2 3-phenyl-2-oxopropanoate + 2 ATP + H2O → 2 diphosphate + 2 AMP + (-)-microperfuranone + CO2
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + longiborneol
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + (2Z,6E)-hedycaryol
H2O + 4-chlorobenzoate → H+ + 4-hydroxybenzoate + chloride
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + (+)-epi-α-bisabolol
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + kunzeaol
H2O + (indol-3-yl)acetamide → ammonium + (indol-3-yl)acetate
H2O + indol-3-ylmethylisothiocyanate-glutathione → L-glutamate + S-(indol-3-ylmethylisothiocyanyl)-L-cysteinylglycine
H2O + 4-hydroxy-3-methylbenzaldehyde + NADP+ → 2 H+ + NADPH + 4-hydroxy-3-methylbenzoate
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + 5-hydroxy-α-gurjunene
H2O + 3'-amino-3'-deoxyATP → 2 H+ + diphosphate + 3'-amino-3'-deoxyAMP
H2O + N1-acetylspermine + oxygen → hydrogen peroxide + 3-acetamidopropanal + spermidine
H2O + (2E,6E)-farnesyl diphosphate → diphosphate + τ-cadinol
H2O + K+ + ATP → K+ + phosphate + ADP
H2O + (-)-dehydrodiconiferyl aldehyde + NAD+ → 2 H+ + NADH + (-)-dehydrodiconiferyl acid
2 H2O + acetyl-CoA → 5 H+ + coenzyme A + glyoxylate
β-L-arabinofuranosyl-(1→2)-β-L-arabinofuranose + H2O → 2 β-L-arabinofuranose
H2O + GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala → N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate + L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine
H2O + XXLG xyloglucan oligosaccharide → β-D-galactopyranose + XXXG xyloglucan oligosaccharide
H2O + 1-O-(2-acetamido-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol 3-phosphate → 1-(2-acetamido-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol + phosphate
H2O + lipid + ATP → lipid + phosphate + ADP
H2O + S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine → glycine + S-(4-hydroxy-nonenal-3-yl)-L-cysteine
H2O + 1-(5-phospho-β-D-ribosyl)-AMP → 1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide
H2O + deoxycholoyl-CoA → coenzyme A + H+ + deoxycholate
H2O + (R)-N-formyl-β-hydroxy-L-kynurenine → (R)-β-hydroxy-L-kynurenine + formate + H+
H2O + hypoxanthine → 6,8-dihydroxypurine
H2O + γ-glutamylanilide diol → 1-aminocyclohexa-3,5-diene-1,2-diol + L-glutamate
2 an oxidized ferredoxin [iron-sulfur] cluster + phosphate + ADP + 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a ← 2 a reduced ferredoxin [iron-sulfur] cluster + H2O + H+ + ATP + 3-devinyl-3-(1-hydroxyethyl)chlorophyllide a
2 H2O + 5-oxo-L-proline + ATP → H+ + L-glutamate + phosphate + ADP
H2O + futalosine → dehypoxanthine futalosine + hypoxanthine
H2O + H+ + 2-aminoprop-2-enoate → pyruvate + ammonium
H2O + 2'-deoxyadenosine 3'-monophosphate → phosphate + 2'-deoxyadenosine
H2O + geranylfarnesyl diphosphate → sesterfisherol + diphosphate
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA ← H2O + 3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA
H2O + carbamoyl phosphate + tobramycin + ATP → H+ + diphosphate + phosphate + nebramycin 5' + AMP
H2O + sulfoethylcysteine → coenzyme M + pyruvate + ammonium
H2O + norspermine + oxygen → norspermidine + hydrogen peroxide + 3-aminopropanal
H2O + 3'-ketolactose → 3-keto-β-D-galactose + β-D-glucopyranose
H2O + GTP → cyclic pyranopterin phosphate + diphosphate
H2O + oxygen + N-methyl-L-tryptophan → hydrogen peroxide + formaldehyde + L-tryptophan
H2O + putrescine + ATP → putrescine + phosphate + ADP
H2O + glycocholate → glycine + cholate
H2O + 1,3,7-trimethyl-5-hydroxyisourate → H+ + 3,6,8-trimethyl-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline
3 an oxidized electron donor + FMN + H2O + L-glutamate + oxygen → 3 a reduced electron donor + 8-amino-8-demethylriboflavin 5'-phosphate + 2-oxoglutarate + H+ + CO2
H2O + H+ + cytosine → ammonium + uracil
H2O + 2'-deoxyribose + ATP → 2'-deoxyribose + phosphate + ADP
H2O + dIDP → H+ + phosphate + dIMP
an oxidized electron donor + H2O + 2,4-xylenol → 4-hydroxy-3-methylbenzyl alcohol + a reduced electron donor
H2O + spermine + oxygen → hydrogen peroxide + 3-aminopropanal + spermidine
an oxidized electron donor + 4-(4-hydroxy-3-methoxyphenyl)-tetrahydro-3H-furo[3,4-c]furan-1-one + H2O → 4-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-tetrahydrofuro[3,4-c]furan-1-one + a reduced electron donor
H2O + neo-λ-carrahexaose → neo-λ-carrabiose + neo-λ-carratetraose
H2O + luteolin 7-O-β-D-glucuronide → β-D-glucuronate + H+ + luteolin
α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid A + H2O → Kdo-lipid A + 3-deoxy-α-D-manno-2-octulosonate
L-arabinono-1,4-lactone + H2O → H+ + L-arabinonate
H2O + XXXG xyloglucan oligosaccharide → α-D-xylosyl-(1->6)-β-D-glucosyl- (1->4)-β-D-glucose + α-D-xylosyl-(1->6)-β-D-glucosyl-(1->4)-[α-D-xylose-(1,6)-]-β-D-glucose
phaseollidin-hydrate ← H2O + (-)-phaseollidin
H2O + L-aspartate 4-semialdehyde + NAD+ → 2 H+ + NADH + L-aspartate
H2O + maleamate → ammonium + maleate
H2O + 1-alkyl-2-acyl-phosphatidylcholine + ATP → 1-alkyl-2-acyl-phosphatidylcholine + phosphate + ADP
H2O + P1,P4-bis(5'-adenosyl) tetraphosphate → 2 H+ + 2 ADP
H2O + γ-glutamyl-L-putrescine + oxygen → hydrogen peroxide + 4-(γ-L-glutamylamino)butanal + ammonium
H2O + 3-methylbenzaldehyde + NAD+ → 2 H+ + NADH + 3-methylbenzoate
H2O + S-succinylglutathione → H+ + glutathione + succinate
H2O + 6-deoxy-6-sulfo-D-glucono-1,5-lactone → 6-deoxy-6-sulfo-D-gluconate + H+
H2O + H+ + pheophorbide a → methanol + CO2 + pyropheophorbide a
H2O + 2,6-diaminopyridine + ATP → 2,6-diaminopyridine + phosphate + ADP
H2O + a reduced electron donor + ground state firefly oxyluciferin → an oxidized electron donor + thioglycolate + 2-cyano-6-hydroxybenzothiazole + H+
D-erythrose 4-phosphate + H2O + NAD+ → 2 H+ + 4-phospho-D-erythronate + NADH
H2O + 2-keto-6-acetamidocaproate + NAD+ → 5-acetamidovalerate + NADH + H+ + CO2
H2O + ATP + daunorubicin → phosphate + ADP + daunorubicin
H2O + guanosine 3'-monophosphate → guanosine + phosphate
H2O + oligosaccharide with β-D-xylopyranosyl-(1->4)-β-D-xylopyranosyl-(1->4)-β-D-xylopyranose at the reducing end → oligosaccharide with β-D-xylopyranosyl-(1->4)-α-D-xylopyranose at the reducing end + β-D-xylopyranose
H2O + (indol-3-yl)acetyl-L-alanine → L-alanine + (indol-3-yl)acetate
H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine → L-glutamate + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine
FAD + H2O + H+ + cis-zeatin → FADH2 + 3-methyl-4-cis-hydroxy-2-butenal + adenine
H2O + furcatin → β-D-apiofuranosyl-(1->6)-D-glucose + chavicol
H2O + 3,6-dichloropyridine-2,5-dione → 3-chloro-6-hydroxypyridine-2,5-dione + H+ + chloride
H2O + sn-glycero-3-phospho-1-inositol → myo-inositol + H+ + sn-glycerol 3-phosphate
H2O + ferric coprogen + ATP → H+ + phosphate + ferric coprogen + ADP
H2O + cinnamaldehyde + oxygen → hydrogen peroxide + trans-cinnamate + H+
H2O + naringin → prunin + β-L-rhamnopyranose
an oxidized electron donor + 4,4'-diapolycopene-4-al + H2O → 4,4'-diapolycopene-4-oate + a reduced electron donor + H+
(S)-2-amino-6-oxohexanoate + H2O + NAD+ → 2 H+ + NADH + L-2-aminoadipate
(31R)-8-ethyl-12-methylbacteriochlorophyllide d ← H2O + 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d
H2O + abieta-7,13-diene-18-al + NAD+ → 2 H+ + NADH + abieta-7,13-diene-18-oate
H2O + 2-(β-D-glucosyl)-sn-glycerol 3-phosphate → 2-O-(β-D-glucopyranosyl)-glycerol + phosphate
H2O + 2-sulfinoacetaldehyde → acetaldehyde + H+ + sulfite
H2O + 2-hydroxy-5-carboxymethylmuconate semialdehyde + NAD+ → 2 H+ + 5-carboxymethyl-2-hydroxymuconate + NADH
H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-ω-(methylsulfanyl)octan-1-imine → L-glutamate + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)octan-1-imine
H2O + P1,P5-bis(5'-adenosyl) pentaphosphate → adenosine tetraphosphate + H+ + AMP
H2O + NAD+ + 5-hydroxyindole acetaldehyde → 2 H+ + NADH + 5-hydroxyindole acetate
N4-(β-N-acetyl-D-glucosaminyl)-L-asparagine + H2O → N-acetyl-β-glucosaminylamine + H+ + L-aspartate
H2O + N-acetyl-α-D-glucosamine + ATP → N-acetyl-α-D-glucosamine + phosphate + ADP
H2O + 3'-phosphoadenylyl-sulfate → phosphate + adenosine 5'-phosphosulfate
H2O + 6,3-dihydroxy-2-pyridinone → 2-oxoglutaramate
an oxidized electron donor + H2O + (8E,10S)-10-hydroxyoctadec-8-enoate → (8E,10S)-10-hydroperoxyoctadec-8-enoate + a reduced electron donor
H2O + N-(β-D-glucosyl)-(indol-3-yl)acetyl-L-glutamate → L-glutamate + N-β-D-glucosyl-(indol-3-yl)acetate
H2O + rifampicin + ATP → 2 H+ + phosphate + 21-phosphorifampicin + AMP
H2O + (2-oxindol-3-yl)acetyl-L-aspartate → L-aspartate + 2-oxoindole-3-acetate
H2O + 3-maleylpyruvate → pyruvate + H+ + fumarate
H2O + 4-methylumbelliferyl glucoside → 4-methylumbelliferone + β-D-glucopyranose
H2O + geranyl diphosphate → 1,8-cineole + diphosphate
H2O + 3-maleylpyruvate → pyruvate + H+ + maleate
H2O + α-D-glucose 6-phosphate → phosphate + α-D-glucopyranose
H2O + spermine + oxygen → hydrogen peroxide + propane-1,3-diamine + 1-(3-aminopropyl)-4-aminobutanal
H2O + squalene → hopan-22-ol
H2O + 5-guanidino-2-oxopentanoate → 5-amino-2-oxopentanoate + urea
H2O + oxygen + (+)-cis-abscisic aldehyde → hydrogen peroxide + H+ + 2-cis-abscisate
an oxidized electron donor + H2O + purine → a reduced electron donor + hypoxanthine
H2O + NADP+ + 18-oxo-oleate → 2 H+ + NADPH + α,ω-9Z-octadecenedioate
H2O + CDP-choline → 2 H+ + phosphocholine + CMP
H2O + O-succinyl-L-homoserine → 2-oxobutanoate + H+ + ammonium + succinate
H2O + phenyl-Coβ-adenosylcobamide 5'-phosphate → phenyl-Coβ-adenosylcobamide + phosphate
H2O + leukotriene-C4 → L-glutamate + leukotriene-D4
H2O + NAD+ + 3-methoxy-4-hydroxyphenylglycolaldehyde → 2 H+ + NADH + vanillyl mandelate
5-chloro-5-deoxy-D-ribono-γ-lactone + H2O → 5-chloro-5-deoxy-D-ribonate + H+
H2O + ergosteryl oleate → ergosterol + oleate + H+
H2O + 2-oxoglutaramate → 2-oxoglutarate + ammonium
α-ribazole 5'-phosphate + H2O → α-ribazole + phosphate
H2O + maltose → 2 α-D-glucopyranose
H2O + UTP → H+ + phosphate + UDP
2 H2O + XLLG xyloglucan oligosaccharide → 2 β-D-galactopyranose + XXXG xyloglucan oligosaccharide
(4S,5R)-4,5,6-trihydroxy-2-iminohexanoate + H2O + H+ → 2-dehydro-3-deoxy-D-gluconate + ammonium
2 an oxidized ferredoxin [iron-sulfur] cluster + phosphate + ADP + bacteriochlorophyllide g ← 2 a reduced ferredoxin [iron-sulfur] cluster + H2O + H+ + ATP + 3,8-divinyl chlorophyllide a
H2O + 9-(methylsulfanyl)-2-oxononanoate + acetyl-CoA → coenzyme A + 2-[(7'-methylsulfanyl)heptyl]malate + H+
3-deacetyl-3-(1-hydroxyethyl)-bacteriochlorophyllide g ← H2O + bacteriochlorophyllide g
H2O + α,α-trehalose 6-phosphate → β-D-glucose 6-phosphate + β-D-glucopyranose
H2O + serotonin + oxygen → hydrogen peroxide + ammonium + 5-hydroxyindole acetaldehyde
2 NAD+ + H2O + trimethylaminoacetone + oxygen → 2 NADH + 3 H+ + glycine betaine + CO2
H2O + m7GTP → N7-methylguanosine 5'-phosphate + H+ + diphosphate
3 H+ + 5 NADPH + 9 malonyl-CoA + H2O + acetyl-CoA → 10 coenzyme A + 5 NADP+ + 9 CO2 + 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate
H2O + arsenite + ATP → arsenite + H+ + phosphate + ADP
2 H+ + H2O + 5-ureidoimidazole-4-carboxylate → 5-aminoimidazole-4-carboxylate + ammonium + CO2
H2O + L-cystathionine → L-homocysteine + pyruvate + ammonium
H2O + stipitatonate → stipitatate + H+ + CO2
H2O + stachyose + ATP → phosphate + stachyose + ADP
H2O + N-acetylpuromycin → acetate + puromycin
H2O + NAD+ + L-leucine → NADH + 4-methyl-2-oxopentanoate + H+ + ammonium
H2O + N-3-fumaroyl-L-2,3-diaminopropanoate + L-glutamine + ATP → N-3-fumaramoyl-L-2,3-diaminopropanoate + H+ + L-glutamate + diphosphate + AMP
H2O + di-trans,octa-cis-undecaprenyl diphosphate → H+ + phosphate + di-trans,octa-cis-undecaprenyl phosphate
H2O + L-cystine → S-sulfanyl-L-cysteine + pyruvate + ammonium
H2O + isopyridoxal + NAD+ → 2 H+ + 5-pyridoxate + NADH
H2O + 2-formylaminobenzaldehyde → O-aminobenzaldehyde + formate + H+
H2O + 4-(2-iminoethyl)phenol → (4-hydroxyphenyl)acetaldehyde + ammonium
H2O + glyoxylate + oxygen → hydrogen peroxide + H+ + oxalate
H2O + neoagarobiose → β-D-galactopyranose + 3,6-anhydro-α-L-galactopyranose
H2O + sn-glycerol 3-phosphate → glycerol + phosphate
H2O + (E)-4-coumaroyl-CoA + 3-oxooctanoyl-CoA → 2 coenzyme A + 4-coumaroylhexanoylmethane + CO2
H2O + 1,2-epoxy-2-methylpropane → 2-methylpropane-1,2-diol
H2O + thiamine phosphate → thiamine + phosphate
H2O + isatin → isatinate + H+
H2O + N-formimino-L-glutamate → formamide + L-glutamate
(S)-3-hydroxydecanoyl-CoA ← H2O + (2E)-dec-2-enoyl-CoA
H2O + N-acetyl-β-D-glucosamine + oxygen → N-acetyl-D-glucosaminate + hydrogen peroxide + H+
maltohexaose + H2O → maltopentaose + α-D-glucopyranose
2 H2O + an oxidized electron donor + phenylacetyl-CoA → 3 H+ + coenzyme A + a reduced electron donor + phenylglyoxylate
H2O + XTP → H+ + diphosphate + XMP
H2O + D-myo-inositol (3,4)-bisphosphate → 1D-myo-inositol 3-monophosphate + phosphate
H2O + H+ + isoguanine → xanthine + ammonium
H2O + formate + ATP → formate + phosphate + ADP
H2O + NAD+ + salicylaldehyde → 2 H+ + salicylate + NADH
2 H2O + 3 oxygen + 5-hydroxymethylfurfural → 2 H+ + 3 hydrogen peroxide + furan-2,5-dicarboxylate
H2O + 4-imidazolone-5-propanoate → formyl-L-isoglutamine
2 H+ + H2O + (S)-ureidoglycolate → 2 ammonium + glyoxylate + CO2
H2O + tert-butyl formate → tert-butyl alcohol + formate + H+
2 H2O + NAD+ + (S)-1-pyrroline-5-carboxylate → NADH + H+ + L-glutamate
H2O + 4-hydroxybenzoyl-CoA → coenzyme A + H+ + 4-hydroxybenzoate
H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethan-1-imine → L-glutamate + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethan-1-imine
H2O + 4-imidazolone-5-propanoate → N-formimino-L-glutamate
H2O + oxygen + D-lysine → hydrogen peroxide + 6-amino-2-oxohexanoate + ammonium
coenzyme A + H2O + crotonyl-CoA → 2 H+ + 2 acetyl-CoA
H2O + sucrose 6F-phosphate → sucrose + phosphate
3-chloro-2-methyl-dienelactone + H2O → 3 H+ + 3-chloro-2-methyl-maleylacetate
2 phosphate + 2 ADP + an oxidized ferredoxin [iron-sulfur] cluster + cyclohex-1,5-diene-1-carbonyl-CoA ← 2 H2O + 2 ATP + a reduced ferredoxin [iron-sulfur] cluster + benzoyl-CoA
H2O + Coα-[α-(2-methyladenin-9-yl)]-Coβ-adenosylcobamide 5'-phosphate → Coα-[α-(2-methyladenin-7-yl)]-Coβ-adenosylcobamide + phosphate
H2O + α, α'-trehalose 6-α-mycolate + ATP → H+ + α, α'-trehalose 6-α-mycolate + phosphate + ADP
melibionate + H2O → D-gluconate + α-D-galactopyranose
H2O + 3-chloro-6-hydroxypyridine-2,5-dione → 3,6-dihydroxypyridine-2,5-dione + H+ + chloride
H2O + VAI-1 → H+ + N-(3-oxohexanoyl)-L-homoserine
S-ethyl-L-cysteine + H2O + oxygen → hydrogen peroxide + ethiin
2 an oxidized ferredoxin [iron-sulfur] cluster + 2 phosphate + 2 ADP + 3,8-divinyl chlorophyllide a ← 2 H2O + 2 a reduced ferredoxin [iron-sulfur] cluster + 2 ATP + 3,8-divinyl protochlorophyllide a
3 H2O + 7,8-dihydromonapterin triphosphate → 2 H+ + 3 phosphate + 7,8-dihydromonapterin
H2O + H+ + sinigrin → 2-propenyl-thiohydroximate-O-sulfate + α-D-glucopyranose
1-oleoyl-sn-glycerol + H2O → oleate + glycerol + H+
H2O + palmitoyl-CoA → coenzyme A + palmitate + H+
H2O + ureidomalonate → malonate + H+ + urea
H2O + 2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA → coenzyme A + 2-hydroxycyclohepta-1,4,6-triene-1-carboxylate
H2O + (2R)-2-chloro-2,5-dihydro-5-oxofuran-2-acetate → 2 H+ + 2-maleylacetate + chloride
an oxidized electron donor + H2O + (4R)-limonene → (4R)-perillyl alcohol + a reduced electron donor
O-carbamoyl-deacetylcephalosporin C + H2O → 2 H+ + 7-α-hydroxy-O-carbamoyl-deacetylcephalosporin C
H2O + γ-tomatine → β-D-glucopyranose + tomatidine galactoside
H2O + raffinose + ATP → raffinose + phosphate + ADP
H2O + MMF1 butenolide intermediate → H2O + methylenomycin furan 1
H2O + 2,5-dioxopentanoate + NADP+ → 2 H+ + NADPH + 2-oxoglutarate
H2O + (2Z)-4-oxobut-2-ene-1,2,4-tricarboxylate → 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate
2,5-dichloro-trans-dienelactone + H2O → 2,5-dichloromaleylacetate + H+
H2O + prop-2-ynal + NAD+ → 2 H+ + propynoate + NADH
H2O + glyoxal + oxygen → hydrogen peroxide + glyoxylate + H+
Mn2+ + H2O + ATP → Mn2+ + phosphate + ADP
H2O + ITP → H+ + phosphate + IDP
H2O + glycyl-L-proline → glycine + L-proline
myo-inositol + H2O + ATP → myo-inositol + phosphate + ADP
H2O + 5-(methylsulfanyl)-2-oxopentanoate + acetyl-CoA → coenzyme A + 2-[(3'-methylsulfanyl)propyl]malate + H+
H2O + glutathione → glycine + γ-L-glutamyl-L-cysteine
H2O + 6-hydroxypseudooxynicotine + oxygen → methylamine + hydrogen peroxide + 4-(6-hydroxy-pyridin-3-yl)-4-oxobutanal
H2O + nitroethane + oxygen → hydrogen peroxide + acetaldehyde + H+ + nitrite
H2O + glycerol 1,2-cyclic phosphate → H+ + sn-glycerol 3-phosphate
H2O + D-gluconate 6-phosphate → D-gluconate + phosphate
bacterioruberin ← 2 H2O + bisanhydrobacterioruberin
H2O + L-cysteine + ATP → L-cysteine + phosphate + ADP
H2O + S-adenosyl-L-methionine → S-methyl-5'-thioadenosine + L-homoserine + H+
xanthine + H2O → H+ + 5-ureidoimidazole-4-carboxylate
H2O + vanillin + NAD+ → 2 H+ + vanillate + NADH
H2O + N-acetyl-α-D-galactosamine + ATP → N-acetyl-α-D-galactosamine + phosphate + ADP
H2O + 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate → 2 H+ + phosphate + phytate
H2O + ATP + Na+ → H+ + phosphate + ADP + Na+
2 H2O + dimethylsulfoniopropioyl-CoA → 2 H+ + coenzyme A + 3-hydroxypropanoate + dimethyl sulfide
H2O + D-myo-inositol (1,2,3,4,5)-pentakisphosphate → D-myo-inositol (1,2,3,4) tetrakisphosphate + phosphate
H2O + [(3S)-4-(6-methyloctanoyl)-5-oxooxolan-3-yl]methyl phosphate → SCB3 butanolide intermediate + phosphate
H2O + β-D-cellobiose + ATP → phosphate + β-D-cellobiose + ADP
H2O + S-(4-hydroxy-3-methylbutan-2-yl)-L-cysteine → pyruvate + ammonium + 2-methyl-3-sulfanylbutan-1-ol
H2O + stearoyl-CoA → coenzyme A + stearate + H+
1,1'-dihydroxy-neurosporene ← 1-hydroxyneurosporene + H2O
H2O + dGDP → H+ + phosphate + dGMP
H2O + S-(5-hydroxy-2-furoyl)-CoA → 2-oxoglutaryl-CoA + H+
H2O + 5-nitroanthranilate + H+ → 5-nitrosalicylate + ammonium
H2O + pyridoxal 5'-phosphate → pyridoxal + phosphate
H2O + (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-al + NAD+ → 2 H+ + NADH + (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate
H2O + MMF4 butenolide intermediate → H2O + methylenomycin furan 4
phosphoenolpyruvate + H2O + ATP → phosphoenolpyruvate + phosphate + ADP
H2O + geranylgeranyl diphosphate → (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol + diphosphate
H2O + ferric aerobactin + ATP → ferric aerobactin + phosphate + ADP
H2O + S-benzyl-L-cysteine → pyruvate + ammonium + benzyl thiol
GDP-α-D-glucose + H2O → H+ + β-D-glucopyranose + GDP
3 H2O + GTP → 2 H+ + 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate + diphosphate
H2O + 5-acetamidovalerate → acetate + 5-aminopentanoate
H2O + CMP → cytidine + phosphate
H2O + L-tryptophan → pyruvate + ammonium + indole
(9Z,12Z)-15,16-epoxyoctadeca-9,12-dienoate + H2O → (9Z,12Z)-15,16-dihydroxyoctadeca-9,12-dienoate
H2O + N-formylmaleamate → maleamate + formate + H+
H2O + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-glutamine + ATP → ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine + H+ + L-glutamate + phosphate + ADP
H2O + α-lactose + ATP → α-lactose + phosphate + ADP
H2O + (2Z,4E)-2-hydroxy-6-oxo-6-sulfonatohexa-2,4-dienoate → 2 H+ + (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + sulfite
an oxidized electron donor + H2O + (S)-nicotine → nornicotine + a reduced electron donor + formaldehyde
H2O + α-D-ribose-1-(methyl)phosphonate-5-triphosphate → α-D-ribose-1-methylphosphonate 5-phosphate + H+ + diphosphate
H2O + 7,8-dihydropterin + H+ → 7,8-dihydrolumazine + ammonium
H2O + 3,4,15-triacetylnivalenol → acetate + 4,15-diacetylnivalenol + H+
H2O + 5-formylfuran-2-carboxylate → 5-(dihydroxymethyl)furan-2-carboxylate
H2O + γ-L-glutamyl-(S)-methyl-L-cysteine → L-glutamate + S-methyl-L-cysteine
H2O + ITP → H+ + diphosphate + IMP
3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA ← H2O + 3-(4-methylpent-3-en-1-yl)-pent-2-enedioyl-CoA
H2O + 8-hydroxypurine → 6,8-dihydroxypurine
1-hydroxyneurosporene ← all-trans neurosporene + H2O
H2O + NAD+ + methylglyoxal → 2 H+ + NADH + pyruvate
biotin + H2O + ATP → biotin + phosphate + ADP
H2O + 4-hydroxybenzyl isothiocyanate → 4-hydroxybenzyl alcohol + thiocyanate + H+
H2O + ellagic acid → H+ + 3,4,8,9,10-pentahydroxy-6-oxobenzo[c]chromene-1-carboxylate
2 H+ + 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate ← H2O + (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate
H2O + 3-methylbutyl acetate → acetate + 3-methylbutanol + H+
2 myristoyl-CoA + H2O → 2 coenzyme A + (2R)-2-dodecyl-3-oxohexadecanoate + H+
2 H2O + trans-cinnamate + NAD+ → 2 H+ + acetate + NADH + benzoate
H2O + NADP+ + magnesium-protoporphyrin IX 13-monomethyl ester → NADPH + H+ + 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester
H2O + NAD(P)+ + 3,4-dihydroxybenzaldehyde → 2 H+ + protocatechuate + NAD(P)H
H2O + 2-chloro-N-(2,6-diethylphenyl)-N-methylacetamide → methanol + 2-chloro-N-(2,6-diethylphenyl)acetamide
H2O + dihydrocoumarin → H+ + melilotate
H2O + Ag+ + ATP → Ag+ + phosphate + ADP
H2O + GTP → 7,8-dihydroneopterin 3'-triphosphate + formate + H+
H2O + indole-3-carbinonium ion → H+ + indole-3-carbinol
H2O + L-aspartate + L-glutamine + ATP → H+ + L-glutamate + L-asparagine + diphosphate + AMP
H2O + ATP + cob(I)inamide → diphosphate + phosphate + adenosylcobinamide
H2O + adenosine tetraphosphate → 2 H+ + phosphate + ATP
cis-dienelactone + H2O → 2-maleylacetate + H+
H2O + ATP + methyl-β-D-galactoside → H+ + phosphate + ADP + methyl-β-D-galactoside
H2O + ground state fungal oxyluciferin → pyruvate + H+ + trans-caffeate
H2O + L-threonine 3-O-phosphate → L-threonine + phosphate
H2O + 2'-hydroxybiphenyl-2-sulfinate → 2-hydroxybiphenyl + H+ + sulfite
H2O + angiotensin II → L-phenylalanine + angiotensin-(1-7)
1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene ← rhodopin + H2O
H2O + 4-nitrophenyl phosphate → 4-nitrophenol + H+ + phosphate
H2O + 17-O-acetylajmaline → acetate + H+ + ajmaline
H2O + 3,15-acetyldeoxynivalenol → acetate + H+ + 15-acetyldeoxynivalenol
H2O + 17-O-acetylnorajmaline → acetate + H+ + norajmaline
H2O + 1-myristoyl-sn-glycerol 3-phosphate → 1-myristoyl-sn-glycerol + phosphate
4 H2O + 4 L-glutamine + 4 ATP + adenosyl-cob(III)yrinate a,c-diamide → 4 H+ + 4 L-glutamate + 4 phosphate + 4 ADP + adenosylcobyrate
tuberculosinyl diphosphate + H2O → (13R)-isotuberculosinol + diphosphate
H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-2-(4-hydroxyphenyl)ethan-1-imine → (Z)-N-hydroxy-2-(4-hydroxyphenyl)acetimidothioate + pyruvate + H+ + ammonium
H2O + L-alanyl-L-glutamine → L-alanine + L-glutamine
H2O + putrescine + oxygen → hydrogen peroxide + 4-aminobutanal + ammonium
H2O + (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate → anthranilate + (2E)-2-hydroxypenta-2,4-dienoate + H+
H2O + 3,4-dihydroxybenzaldehyde + oxygen → protocatechuate + hydrogen peroxide + H+
H2O + oxygen + benzylamine → hydrogen peroxide + benzaldehyde + ammonium
H2O + dGMP → phosphate + 2'-deoxyguanosine
H2O + 6-carboxyhex-2-enoyl-CoA → 3-hydroxypimeloyl-CoA
H2O + guanosine + ATP → guanosine + phosphate + ADP
H2O + chlorophyll a → phytol + H+ + chlorophyllide a
H2O + Microcin C + ATP → Microcin C + phosphate + ADP
H2O + D-alanine → ammonia + pyruvate
H2O + 3-aminopropanal + NAD(P)+ → 2 H+ + β-alanine + NAD(P)H
H2O + thiosulfate + ATP → phosphate + thiosulfate + ADP
H2O + 2,4-dinitrocyclohexan-1-one → 4,6-dinitrohexanoate + H+
H2O + amino-parathion → diethylthiophosphate + 4-aminophenol + H+
H2O + 4-coumarate → acetate + 4-hydroxybenzaldehyde
2 H2O + acetone + ATP + CO2 → 2 phosphate + 3 H+ + acetoacetate + AMP
H2O + 2,4-dinitroanisole → 2,4-dinitrophenol + methanol + H+
H2O + ε-rhodomycinone → 15-demethoxy-ε-rhodomycinone + methanol + H+
H2O + 5,10-methylene-tetrahydromethanopterin + 3-methyl-2-oxobutanoate → tetrahydromethanopterin + 2-dehydropantoate
H2O + (+)-7-epi-jasmonoyl-CoA → coenzyme A + H+ + (+)-7-epi-jasmonate
H2O + (E)-2-benzylidenesuccinyl-CoA → 2-carboxymethyl-3-hydroxyphenylpropanoyl-CoA
tuberculosinyl diphosphate + H2O → tuberculosinol + diphosphate
H2O + uridine 2'-monophosphate → uridine + phosphate
H2O + H+ + 2-hexaprenyl-3-methyl-6-methoxyaminophenol → ammonium + 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol
H2O + aspirin → salicylate + acetate + H+
H2O + glucoiberin + oxygen → methanesulfonate + H+ + 3-hydroxypropyl-glucosinolate
H2O + 7,8-dihydroneopterin 2'-phosphate → 7,8-dihydroneopterin + phosphate
H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)octan-1-imine → pyruvate + (E)-ω-(methylsulfanyl)octyl-thiohydroximate + ammonium
H2O + sirohydrochlorin + L-glutamine + ATP → H+ + L-glutamate + phosphate + siroamide + ADP
H2O + (S)-(+)-allantoin → H+ + allantoate
H2O + α-tomatine → α-D-xylopyranose + β1-tomatine
2 H2O + CTP → 2 H+ + 2 phosphate + CMP
H2O + oxygen + D-alanine → hydrogen peroxide + pyruvate + ammonium
H2O + UDP-N-acetyl-α-D-glucosamine → N-acetyl-α-D-mannosamine + H+ + UDP
H2O + anandamide → ethanolamine + arachidonate
H2O + phosphorylated MMF2 butenolide intermediate → MMF2 butenolide intermediate + phosphate
2 H+ + H2O + allantoate → ammonium + (S)-ureidoglycine + CO2
H2O + dalnigrein 7-O-β-D-apiofuranosyl-(1-6)-β-D-glucopyranoside → β-D-apiofuranosyl-(1->6)-D-glucose + dalnigrein
phosphoenolpyruvate + H2O + 1-deoxy-1-imino-D-erythrose 4-phosphate → phosphate + 3,4-dideoxy-4-amino-D-arabino-heptulosonate 7-phosphate
3 a reduced electron donor + H2O + ATP + Ni-sirohydrochlorin a,c-diamide → 3 an oxidized electron donor + phosphate + ADP + 15,173-seco-F430-173-acid
2 H2O + L-alanyl-(2S,3E)-amino-4-methoxy-but-3-enoyl-L-alanine → 2 L-alanine + (2S,3E)-2-amino-4-methoxy-but-3-enoate
3 coenzyme A + H2O + Δ2,5-3,4,4-trimethylpimeloyl-CoA → 3 acetyl-CoA + H+ + isobutanoyl-CoA
H2O + phosphorylated MMF5 butenolide intermediate → MMF5 butenolide intermediate + phosphate
2-phosphoglycolate + H2O → glycolate + phosphate
H2O + 4-oxo-4-(pyridin-3-yl)butanal + NADP+ → 2 H+ + 4-oxo-4-(3-pyridyl)-butanoate + NADPH
H2O + salicyl-CoA → coenzyme A + salicylate + H+
H2O + L-glutamate-5-semialdehyde + NAD+ → 2 H+ + NADH + L-glutamate
phosphoenolpyruvate + H2O + 4-O-acetyl-N-acetylmannosamine → N-acetyl-7-O-acetylneuraminate + phosphate
H2O + paraxanthine + oxygen → hydrogen peroxide + 1,7-dimethylurate
H2O + S-(5-hydroxypentan-3-yl)-L-cysteinylglycine → glycine + S-(5-hydroxypentan-3-yl)-L-cysteine
H2O + D-myo-inositol (1,2,3) trisphosphate → D-myo-inositol (1,2) bisphosphate + phosphate
pyrroloquinoline quinone + H2O + ATP → pyrroloquinoline quinone + phosphate + ADP
H2O + nonane-4,6-dione → pentan-2-one + butanoate + H+
H2O + sn-glycero-3-phospho-1-inositol → 1D-myo-inositol 1-monophosphate + glycerol + H+
H2O + 1-naphthaldehyde + oxygen → 1-naphthoate + hydrogen peroxide + H+
H2O + propanoyl-CoA → coenzyme A + propanoate + H+
H2O + acetamide → acetate + ammonium
coenzyme A + H2O + (2E,5Z)-tetradecenoyl-CoA + oxygen → hydrogen peroxide + acetyl-CoA + (3Z)-dodec-3-enoyl-CoA
H2O + 3-acetyl T-2 toxin → acetate + H+ + T-2 toxin
an oxidized electron donor + H2O + sarcosine → glycine + a reduced electron donor + formaldehyde
H2O + H+ + Fe3+-[diglucosyl-(2,3-dihydroxybenzoylserine)2] complex → salmochelin SX + Fe3+-[salmochelin SX] complex
H2O + 4-guanidinobutanoate → 4-aminobutanoate + urea
H2O + (3R)-2-(2-carboxyethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA → 9-carboxy-6-methyl-3,7-dioxononanoyl-CoA
4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + H2O → N-acetyl-α-D-galactosamine + 4-deoxy-L-threo-hex-4-enopyranuronate
H2O + UDP-N-acetyl-tunicaminyl-uracil → N-acetyl-tunicaminyl-uracil + H+ + UDP
H2O + L-tyrosine + oxygen → hydrogen peroxide + 3-(4-hydroxyphenyl)pyruvate + ammonium
H2O + succinate semialdehyde + NAD+ → 2 H+ + NADH + succinate
H2O + methylguanidinium → methylamine + urea
H2O + (1S,4R)-2,4,5-trichloro-2,5-cyclohexadiene-1-diol → HCl + (1S,4S)-2,5-dichloro-2,5-cyclohexadiene-1,4-diol + H+
H2O + carbamoyl phosphate + kanamycin A + ATP → H+ + diphosphate + phosphate + 6''-O-carbamoylkanamycin A + AMP
H2O + 3-ADP-2-phosphoglycerate → phosphate + 3-ADP-glycerate
H2O + 3-phospho-L-serine → L-serine + phosphate
H2O + hippurate → glycine + benzoate
H2O + L-cystathionine → 2-oxobutanoate + ammonium + L-cysteine
H2O + O-sinapoylcholine → choline + sinapate + H+
H2O + 6-aminohexanoate cyclic dimer → 6-aminohexanoate linear dimer
H2O + malonyl-CoA + L-glutamine + ATP → malonamoyl-CoA + H+ + L-glutamate + diphosphate + AMP
H2O + 5-amino-6-(5-phospho-D-ribitylamino)uracil → 5-amino-6-(D-ribitylamino)uracil + phosphate
H2O + 4-acetamidobutanoate → acetate + 4-aminobutanoate
H2O + (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + NAD+ → 2 H+ + NADH + (2Z,4E)-2-hydroxyhexa-2,4-dienedioate
H2O + S-adenosyl-L-methionine + 12-ethyl-71-hydroxy-8-isobutylbacteriochlorophyllide c → H+ + 5'-deoxyadenosine + L-methionine + 12-ethyl-71,71-dihydroxy-8-isobutylbacteriochlorophyllide c
H2O + 2,3-dioxo-L-gulonate + ATP → 2,3-dioxo-L-gulonate + phosphate + ADP
H2O + geranial + oxygen → hydrogen peroxide + H+ + geranate
H2O + acetaminophen → acetate + 4-aminophenol + H+
an oxidized electron donor + 4,4'-diapolycopen-4,4'-dial + H2O → 4,4'-diapolycopen-4-al-4'-oate + a reduced electron donor + H+
H2O + NADP+ + L-malic semialdehyde → 2 H+ + NADPH + (S)-malate
H2O + D-myo-inositol (1,2,3,4) tetrakisphosphate → D-myo-inositol (2,3,4) trisphosphate + phosphate
H2O + cytidine 5'-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} → CMP + (S)-2-hydroxypropylphosphonate + H+
sn-glycero-3-phosphoethanolamine + H2O → ethanolamine + H+ + sn-glycerol 3-phosphate
H2O + N5-(cytidine 5'-diphosphoramidyl)-L-glutamine → H+ + L-glutamate + cytidine 5'-diphosphoramidate
2-phenylethyl 6-O-β-D-xylopyranosyl-β-D-glucopyranoside + H2O → primeverose + 2-phenylethanol
H2O + ATP + nitric oxide → phosphate + ADP + nitric oxide
H2O + 3,15-acetyldeoxynivalenol → acetate + H+ + 3-acetyldeoxynivalenol
H2O + (4S,7R)-4-isopropenyl-7-methyloxepan-2-one → H+ + (3S,6R)-6-hydroxy-3-isopropenyl-heptanoate
H2O + Na+ + ATP → Na+ + phosphate + ADP
H2O + 1-lauroyl-sn-glycerol 3-phosphate → 1-lauroyl-sn-glycerol + phosphate
H2O + N2-acetyl-L-Lysine → acetate + L-lysine
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)hexan-1-imine → glycine + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)hexan-1-imine
H2O + trehalose-cis-methoxy-mono-mycolate + ATP → H+ + trehalose-cis-methoxy-mono-mycolate + phosphate + ADP
H2O + nisin + ATP → phosphate + nisin + ADP
H2O + glutathione + methylacrylyl-CoA → coenzyme A + H+ + 2-(glutathion-S-yl)-2-carboxypropane
H2O + lanthionine + ATP → lanthionine + H+ + phosphate + ADP
H2O + α-L-rhamnopyranose + ATP → phosphate + α-L-rhamnopyranose + ADP
2 hexadeca-4,7,10,13-tetraene-1-oyl-CoA + H2O → 2 coenzyme A + (6Z,9Z,12Z,15Z)-3-oxo-2-[(2Z,5Z,8Z,11Z)-tetradeca-2,5,8,11-tetraen-1-yl]octadeca-6,9,12,15-tetraenoate + H+
H2O + echinocandin B → linoleate + echinocandin B nucleus
H2O + cyanuric acid → 1-carboxybiuret + H+
H2O + prenyl diphosphate → H+ + phosphate + prenyl phosphate
an oxidized electron donor + H2O + taurine → sulfoacetaldehyde + a reduced electron donor + ammonium
H2O + phosphonoacetaldehyde + NAD+ → 2 H+ + NADH + phosphonoacetate
1'-hydroxy-γ-carotene ← H2O + γ-carotene
4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl--D-galactosamine 6-sulfate + H2O → 4-deoxy-L-threo-hex-4-enopyranuronate + N-acetyl-D-galactosamine 6-O-sulfate
H2O + NAD(P)+ + (S)-1-pyrroline-5-carboxylate → NAD(P)H + H+ + L-glutamate
H2O + 1-(oleoyl)-sn-glycero-3-phosphoethanolamine → sn-glycero-3-phosphoethanolamine + oleate + H+
H2O + chenodeoxycholoyl-CoA → H+ + coenzyme A + chenodeoxycholate
H2O + (E)-4-coumaroyl-CoA + 4-coumaroylacetyl-CoA → 2 coenzyme A + bisdemethoxycurcumin + CO2
H2O + geranyl acetate → acetate + H+ + geraniol
H2O + oxygen + D-glutamate → hydrogen peroxide + 2-oxoglutarate + ammonium
H2O + 3-hydroxybenzoyl-CoA → coenzyme A + H+ + 3-hydroxybenzoate
H2O + NAD(P)+ + iso-arabidopaldehyde → 2 H+ + NAD(P)H + iso-arabidopate
H2O + (2E,6E)-farnesyl diphosphate → (3S,6E)-nerolidol + diphosphate
H2O + L-dopa + oxygen → ammonia + hydrogen peroxide + 3,4-dihydroxyphenylacetaldehyde + CO2
H2O + p-cumic aldehyde + NAD+ → 2 H+ + NADH + p-cumate
H2O + Nω-(ADP-D-ribosyl)-L-arginine → L-arginine + ADP-D-ribose
H2O + H+ + ferric-[(2,3-dihydroxybenzoylserine)2] complex → N-(2,3-dihydroxybenzoyl)-L-serine + Fe3+-[N-(2,3-dihydroxybenzoyl)-L-serine] complex
H2O + (E)-2-methylgeranyl diphosphate → 2-methylisoborneol + diphosphate
an oxidized electron donor + H2O + tyramine → a reduced electron donor + (4-hydroxyphenyl)acetaldehyde + ammonium
H2O + guanosine 2'-monophosphate → guanosine + phosphate
H2O + pre-acinetobactin + ATP → pre-acinetobactin + phosphate + ADP
H2O + β-D-glucose 6-phosphate → phosphate + β-D-glucopyranose
coenzyme A + H2O + NAD+ + (3R)-hydroxy-undecanoyl-CoA + oxygen → hydrogen peroxide + NADH + H+ + (3R)-hydroxy-nonanoyl-CoA + acetyl-CoA
4'-apo-β-carotenal + H2O + NAD+ → 2 H+ + NADH + neurosporaxanthin
H2O + L-threonine + ATP → L-threonine + phosphate + ADP
4 Mn+3 + 6 H2O + oxygen → 12 H+ + 4 MnIVO2
an oxidized electron donor + H2O + (S)-nicotine → a reduced electron donor + (S)-6-hydroxynicotine
H2O + N-formyl-L-methionine → formate + L-methionine
H2O + ferric-enterobactin complex → ferric-[N-(2,3-dihydroxybenzoyl)-L-serine trimer] complex
H2O + N-acetylmuramoyl-L-ala-D-glu-(L)-meso-diaminopimelate -(L)-D-ala → N-acetylmuramoyl-L-ala-D-glu + meso-diaminopimeloyl-alanine
2 H2O + 2 L-glutamine + 2 ATP + cobyrinate → 2 L-glutamate + 2 phosphate + 2 ADP + 3 H+ + cob(II)yrinate a,c-diamide
H2O + dimethylselenopropanoate-amine + oxygen → hydrogen peroxide + ammonium + 3-dimethylselenopropionaldehyde
benzyl alcohol + H+ + 6-hydroxy-2-cyclohexen-one-carboxylate ← H2O + benzyl-6-hydroxy-2-cyclohexene-on-oyl
H2O + 3-sulfinopropanoyl-CoA → propanoyl-CoA + H+ + sulfite
saturated archaetidylinositol phosphate + H2O → saturated archaetidylinositol + phosphate
H2O + deethylsimazine → N-ethylammeline + H+ + chloride
H2O + H+ + dCTP → ammonium + dUTP
H2O + methylenediurea → N-(carboxyaminomethyl)urea + ammonium
H2O + 3-oxo-5,6-didehydrosuberyl-CoA semialdehyde + NADP+ → 2 H+ + 3-oxo-5,6-didehydrosuberyl-CoA + NADPH
2 H2O + UTP → 2 H+ + 2 phosphate + UMP
H2O + S-adenosyl-L-homocysteine → S-Inosyl-L-homocysteine + ammonium
phosphoenolpyruvate + H2O + 2,4-diacetamido-2,4,6-trideoxy-β-L-gulopyranose → 5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonate + phosphate
H2O + NADP+ → NAD+ + phosphate
H2O + 4-[(2Z)-2-(methylimino)ethyl]phenol → methylamine + (4-hydroxyphenyl)acetaldehyde
2-chloro-3-methyl-dienelactone + H2O → 2-chloro-3-methyl-maleylacetate + H+
H2O + 3,4-dihydroxyphenylacetaldehyde + NAD+ → 2 H+ + NADH + 3,4-dihydroxyphenylacetate
H2O + 4-chlorobenzoyl-coA → H+ + 4-hydroxybenzoyl-CoA + chloride
an oxidized electron donor + nonaflavuxanthin + H2O + prenyl diphosphate → flavuxanthin + a reduced electron donor + diphosphate
H2O + 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H+ → 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonium
H2O + rutin → rutinose + H+ + quercetin
H2O + H+ + CTP → ammonium + UTP
2 H2O + 3-cyano-L-alanine + H+ → ammonium + L-aspartate
H2O + galactitol 1-phosphate → phosphate + galactitol
2 an oxidized electron donor + H2O + nornicotine → 2 a reduced electron donor + H+ + norcotinine
H2O + (R)-6-hydroxynicotine + oxygen → hydrogen peroxide + 6-hydroxypseudooxynicotine
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine → L-seryl-glycine + (E)-ω-(methylsulfanyl)butyl-thiohydroximate
H2O + (R)-piperazine-2-carboxamide → ammonium + (R)-piperazine-2-carboxylate
2 H2O + β-carotene → zeaxanthin
H2O + ε-caprolactone → H+ + 6-hydroxyhexanoate
H2O + thiamine triphosphate → thiamine diphosphate + H+ + phosphate
2 K+ + 3 Na+ + H2O + ATP → 2 K+ + 3 Na+ + H+ + phosphate + ADP
H2O + 2'-deoxyguanosine 3'-monophosphate → phosphate + 2'-deoxyguanosine
H2O + H+ + N-cyclopropylammelide → cyclopropylamine + cyanuric acid
H2O + a peptidoglycan dimer with pentapeptide stems (meso-diaminopimelate containing) → a peptidoglycan dimer with pentapeptide stem (meso-diaminopimelate containing) + L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine
4-deoxy-β-D-gluc-4-enuronosyl-(1,4)-N-acetyl--D-galactosamine 6-sulfate + H2O → 4-deoxy-L-threo-hex-4-enopyranuronate + N-acetyl-D-galactosamine 6-O-sulfate
1'-hydroxy-γ-carotene + H2O → 2 H+ + plectaniaxanthin
H2O + N-acetylputrescine → acetate + putrescine
2 an oxidized ferredoxin [iron-sulfur] cluster + phosphate + ADP + 3-deacetyl-3-vinylbacteriochlorophyllide a ← 2 a reduced ferredoxin [iron-sulfur] cluster + H2O + H+ + ATP + chlorophyllide a
H2O + 3'-phosphoadenylyl-sulfate → 2 H+ + adenosine 3',5'-bisphosphate + sulfate
H2O + N-formyl-L-glutamate → formate + L-glutamate
β-D-fructose 1,6-bisphosphate + H2O → β-D-fructofuranose 6-phosphate + phosphate
H2O + N,N-dimethylglycine + oxygen → hydrogen peroxide + formaldehyde + sarcosine
H2O + S-(4-oxo-2-methylpentan-2-yl)-L-cysteinylglycine → glycine + S-(4-oxo-2-methylpentan-2-yl)-L-cysteine
(13E)-8α-hydroxylabd-13-en-15-yl diphosphate ← H2O + geranylgeranyl diphosphate
H2O + N-ethylammeline + H+ → N-ethylammelide + ammonium
FAD + H2O + H+ + trans-zeatin → FADH2 + 3-methyl-4-trans-hydroxy-2-butenal + adenine
H2O + S-(methylmercury)-L-cysteinylglycine → glycine + S-(methylmercury)-L-cysteine
H2O + 4,4'-diaponeurosporenal + NAD+ → NADH + 4,4'-diaponeurosporenoate + H+
H2O + cis-(homo)2aconitate → (-)threo-iso(homo)2citrate
H2O + (glutathion-S-yl)-bimane + ATP → H+ + (glutathion-S-yl)-bimane + phosphate + ADP
H2O + glutathione + ATP → glutathione + phosphate + ADP
(13E)-8α-hydroxylabd-13-en-15-yl diphosphate + H2O → sclareol + diphosphate
H2O + trehalose-trans-methoxy-mono-mycolate + ATP → H+ + trehalose-trans-methoxy-mono-mycolate + phosphate + ADP
H2O + H+ + 5'-deoxyadenosine → ammonium + 5'-deoxyinosine
FAD + H2O + H+ + isopentenyl adenosine → FADH2 + adenosine + 3-methyl-2-butenal
H2O + aminomethylpyrimidine → 4-amino-2-methyl-5-pyrimidinemethanol + ammonium
H2O + D-alanyl-D-alanine → 2 D-alanine
coenzyme A + H+ + dihomocitrate ← H2O + 2-oxoadipate + acetyl-CoA
H2O + 1-18:1-2-16:0-monogalactosyldiacylglycerol → sn-1-lyso-2-16:0-monogalactosyldiacylglycerol + oleate + H+
H2O + 2,4-dinitrophenyl-S-glutathione + ATP → H+ + 2,4-dinitrophenyl-S-glutathione + phosphate + ADP
H2O + N1-acetylspermine + oxygen → hydrogen peroxide + 3-aminopropanal + N1-acetylspermidine
H2O + dUMP → 2'-deoxyuridine + phosphate
H2O + glycolaldehyde + NAD+ → 2 H+ + glycolate + NADH
H2O + t-anethole → pseudoisoeugenol
H2O + trans-O-hydroxybenzylidenepyruvate → pyruvate + salicylaldehyde
H2O + myosin light-chain phosphate → 2 H+ + phosphate + a [myosin light-chain] L-serine
H2O + (2E)-hexadecenal + NAD+ → 2 H+ + (2E)-hexadecenoate + NADH
agmatine + H2O → N-carbamoylputrescine + ammonium
H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethan-1-imine → pyruvate + H+ + ammonium + (E)-2-(1H-indol-3-yl)-1-thioacetohydroximate
3 H+ + H2O + urea-1-carboxylate → 2 ammonium + 2 CO2
(3S,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA ← (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethan-1-imine → L-seryl-glycine + H+ + (E)-2-(1H-indol-3-yl)-1-thioacetohydroximate
H2O + 3-β-hydroxyandrost-5-en-17-one 3-sulfate → 3 H+ + 3-β-hydroxyandrost-5-en-17-one + sulfate
H2O + (S)-2,3,4,5-tetrahydrodipicolinate + succinyl-CoA → coenzyme A + N-succinyl-2-amino-6-ketopimelate
2 oxygen + H2O + adenosine → 2 hydrogen peroxide + H+ + adenin-9-yl riburonosate
Co2+ + H2O + ATP → Co2+ + phosphate + ADP
H2O + 6-hydroxynicotinate + oxygen → hydrogen peroxide + 2,6-dihydroxynicotinate
H2O + 4,5-epoxy-17R-hydroxy-docosahexaenoate → aspirin triggered resolvin D4
H2O + 4,5-epoxy-17R-hydroxy-docosahexaenoate → aspirin triggered resolvin D3
H2O + dTMP → thymidine + phosphate
arabidiol ← H2O + (3S)-2,3-epoxy-2,3-dihydrosqualene
H2O + (S)-3-hydroxy-3-methylglutaryl-CoA → coenzyme A + 3-hydroxy-3-methylglutarate + H+
H2O + benzoyl-CoA → coenzyme A + H+ + benzoate
agmatine + H2O → putrescine + urea
H2O + β-D-ribopyranose + ATP → β-D-ribopyranose + H+ + phosphate + ADP
H2O + 4-guanidinobutyramide → 4-guanidinobutanoate + ammonium
H2O + pyridoxamine 5'-phosphate + oxygen → hydrogen peroxide + pyridoxal 5'-phosphate + ammonium
H2O + D-myo-inositol (1,4,5)-trisphosphate → D-myo-inositol (1,4)-bisphosphate + phosphate
H2O + ammonium + ubiquinone-9 → rhodoquinone-9 + CO2
H2O + L-4-hydroxyglutamate semialdehyde + NAD+ → 2 H+ + NADH + erythro-4-hydroxy-L-glutamate
H2O + NADH → 2 H+ + reduced β-nicotinamide D-ribonucleotide + AMP
2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + L-glutamate → 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2-oxoglutarate + ammonium
H2O + geranylgeranyl diphosphate → (3E,7E)-dolabella-3,7-dien-18-ol + diphosphate
H2O + chorismate → (3R,4R)-3,4-dihydroxy-3,4-dihydrobenzoate + pyruvate
hesperidin + H2O → hesperitin-7-O-β-D-glucoside + β-L-rhamnopyranose
4-deoxy-β-D-gluc-4-enuronosyl-2-sulfate-(1,3)-N-acetyl-β-D-galactosamine + H2O → N-acetyl-β-D-galactosamine + 5-dehydro-4-deoxy-2-O-sulfo-D-glucuronate
H2O + 7-(methylsulfanyl)-2-oxoheptanoate + acetyl-CoA → coenzyme A + 2-[(5'-methylsulfanyl)pentyl]malate + H+
H2O + 2-oxoadipate → glutarate + CO2
H2O + S-adenosyl-L-methionine + (31R)-8-ethyl-71-12-methylbacteriochlorophyllide c → H+ + 5'-deoxyadenosine + L-methionine + (31R)-8-ethyl-71,71-dihydroxy-12-methylbacteriochlorophyllide c
3 S-adenosyl-L-methionine + H2O + magnesium-protoporphyrin IX 13-monomethyl ester → 3 5'-deoxyadenosine + 3 L-methionine + 4 H+ + 3,8-divinyl protochlorophyllide a
H2O + ethyl acetate → acetate + ethanol + H+
H2O + oxaloacetate → acetate + H+ + oxalate
H2O + 4-oxo-4-sulfanylbutanoate → H+ + succinate + hydrogen sulfide
2 H2O + 3-benzyl-3,6 -bis(cysteinyl)- 6-(hydroxymethyl)-diketopiperazine → 2 pyruvate + 2 ammonium + 3-benzyl-3,6 -dithio-6-(hydroxymethyl)-diketopiperazine
H2O + pantetheine → (R)-pantothenate + cysteamine
H2O + 4-methylphenyl-Coβ-adenosylcobamide 5'-phosphate → 4-methylphenyl-Coβ-adenosylcobamide + phosphate
H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-ω-(methylsulfanyl)heptan-1-imine → L-glutamate + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)heptan-1-imine
H2O + pyridoxamine 5'-phosphate → pyridoxamine + phosphate
H2O + 1-oleoyl-sn-glycerol 3-phosphate → 1-oleoyl-sn-glycerol + phosphate
an oxidized electron donor + cholesterol + H2O → 25-hydroxycholesterol + a reduced electron donor
H2O + (2E,4E)-2-amino-5-chlorohexa-2,4-dienedioate + H+ → (2E,4E)-2-chloro-5-hydroxyhexa-2,4-dienedioate + ammonium
H2O + ATP + cyanocob(III)alamin → phosphate + ADP + cyanocob(III)alamin
H2O + all-trans-retinal + ATP → all-trans-retinal + phosphate + ADP
H2O + L-tartrate + ATP → L-tartrate + phosphate + ADP
H2O + (2E,6E)-farnesyl diphosphate → 4-epi-cubebol + diphosphate
H2O + NAD(P)+ + arabidopaldehyde → 2 H+ + NAD(P)H + arabidopate
H2O + L-methionyl-L-alanine dipeptide → L-methionine + L-alanine
H2O + 4-guanidinobutyraldehyde + NAD+ → 2 H+ + 4-guanidinobutanoate + NADH
H2O + 6-O-cis-methoxy-mycolyl-trehalose 6-phosphate → trehalose-cis-methoxy-mono-mycolate + phosphate
H2O + D-xylono-1,5-lactone → D-xylonate + H+
H2O + UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine + D-alanine
H2O + NADPH → NADH + phosphate
H2O + S-methyl-5'-thioadenosine + H+ → ammonium + S-methyl-5'-thioinosine
H2O + L-glutamine + ATP + cobyrinate → H+ + L-glutamate + phosphate + ADP + cob(II)yrinate c-monoamide
actinomycin D + H2O → actinomyc-D monolactone + H+
H2O + L-djenkolate → S-(sulfanylmethyl)-L-cysteine + pyruvate + ammonium
H2O + ATP + hemin → phosphate + ADP + hemin
H2O + H+ + 5-fluorocytosine → ammonium + 5-fluorouracil
(-)-ent-copalyl diphosphate + H2O → ent-manool + diphosphate
H2O + UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + D-alanine
H2O + 1-(5-phospho-β-D-ribosyl)-ATP → H+ + 1-(5-phospho-β-D-ribosyl)-AMP + diphosphate
H2O + 2-carboxy-D-arabinitol 1-phosphate → 2-carboxy-D-arabinitol + phosphate
H2O + (-)-bornyl-diphosphate → diphosphate + (-)-borneol
H2O + 4-fumaryl-acetoacetate → H+ + acetoacetate + fumarate
H2O + phosphocholine → choline + phosphate
H2O + 3,3'-thiodipropanoate → 3-hydroxypropanoate + 3-sulfanylpropanoate
cephalosporin C + H2O → acetate + H+ + deacetylcephalosporin C
H2O + 2-butyloctyl sulfate → H+ + sulfate + 2-butyl-1-octanol
H2O + trypanothione → glutathionylspermidine + glutathione
4 H2O + 5 S0 + oxygen → 2 hydrogen sulfide + 3 H+ + sulfite + thiosulfate
pppGpp + H2O → ppGpp + H+ + phosphate
H2O + Fe3+-[monoglucosyl-enterobactin] complex → H+ + Fe3+-[monoglucosyl-(2,3-dihydroxybenzoylserine)3] complex
H2O + geranylgeranyl diphosphate → (R)-nephthenol + diphosphate
H2O + pyruvate + ubiquinone-8 → acetate + ubiquinol-8 + CO2
H2O + CDP → CMP + H+ + phosphate
5-phospho-α-D-ribose 1-diphosphate + H2O → diphosphate + aldehydo-D-ribose 5-phosphate
H2O + icosanoyl-CoA → coenzyme A + arachidate + H+
H2O + D-myo-inositol (1,2,5,6) tetrakisphosphate → D-myo-inositol (1,2,6) trisphosphate + phosphate
H2O + (glutathion-S-yl)-4-hydroxy-2-nonenal → L-glutamate + S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine
H2O + 8-oxo-dGTP → H+ + diphosphate + 8-oxo-dGMP
H2O + S-(6-hydroxy-4-methylhexan-4-yl)-L-cysteinylglycine → glycine + S-(6-hydroxy-4-methylhexan-4-yl)-L-cysteine
18'-hydroxy-χ,χ-caroten-18-oate + H2O → 5 H+ + synechoxanthin
H2O + aminoacrylate + H+ → ammonium + 3-oxopropanoate
H2O + N-methylmyosmine + H+ → pseudooxynicotine
H2O + NADP+ + L-leucine → ammonia + NADPH + 4-methyl-2-oxopentanoate
H2O + MMF3 butenolide intermediate → H2O + methylenomycin furan 3
H2O + N-acetyl-D-glucosaminyl-N-acetyl-tunicaminyl-uracil → acetate + N-acetyl-D-glucosaminyl-tunicaminyl-uracil
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)nonan-1-imine → L-seryl-glycine + (E)-ω-(methylsulfanyl)nonyl-thiohydroximate
H2O + L-cystathionine + ATP → L-cystathionine + phosphate + ADP
H2O + ATP + urea → phosphate + ADP + urea
H2O + raffinose → sucrose + α-D-galactopyranose
H2O + phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl) → 1-oleoyl-2-palmitoyl-phosphatidylglycerol + phosphate
H2O + (2E,6E)-farnesyl phosphate → (2E,6E)-farnesol + phosphate
H2O + hypotaurine + NAD+ → taurine + NADH + H+
2 H2O + dCTP → ammonium + diphosphate + dUMP
H2O + lauroyl-CoA → coenzyme A + laurate + H+
H2O + L-arginine + oxygen → hydrogen peroxide + 5-guanidino-2-oxopentanoate + ammonium
H2O + N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate → 1,6-anhydro-N-acetyl-β-muramate + N-acetyl-β-D-glucosamine
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-2-(4-hydroxyphenyl)ethan-1-imine → L-seryl-glycine + (Z)-N-hydroxy-2-(4-hydroxyphenyl)acetimidothioate + H+
H2O + leukotriene-D4 → glycine + leukotriene-E4
H2O + 2-amino-2-deoxy-mannitol-6-phosphate → 2-amino-2-deoxy-D-mannitol + phosphate
H2O + urea-1-carboxylate → 2 carbamate + H+
H2O + formononetin-7-O-glucoside-6''-malonate → malonate + H+ + ononin
aminoacetone + H2O + oxygen → hydrogen peroxide + ammonium + methylglyoxal
H2O + mycothiol-bimane conjugate → 1-(2-amino-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol + bimane N-acetyl-L-cysteinyl conjugate
H2O + 3-amino-2-butanol + oxygen → 4 CO2 + ammonium
2 NAD+ + H2O + UDP-N-acetyl-α-D-mannosamine → 2 NADH + 3 H+ + UDP-N-acetyl-α-D-mannosaminuronate
4-(4-hydroxy-3-methoxyphenyl)-tetrahydro-3H-furo[3,4-c]furan-1-one + H2O → 5-(4-hydroxy-3-methoxyphenyl)-4-(hydroxymethyl)oxolane-3-carboxylate + H+
H2O + 5'-deoxyadenosine → 5-deoxy-D-ribose + adenine
H2O + L-cysteinylglycine → glycine + L-cysteine
H2O + α,α-trehalose + ATP → phosphate + α,α-trehalose + ADP
ecdysone 22-phosphate + H2O → ecdysone + phosphate
H2O + 2-oxohexa-4,5-cyclopropyl-5-enoate + acetyl-CoA → coenzyme A + 3-hydroxy-3-carboxy-4,5-cyclopropylhex-5-enoate + H+
H2O + achromobactin + ATP → achromobactin + phosphate + ADP
2 H2O + acryloyl-CoA → coenzyme A + 3-hydroxypropanoate + H+
7-methylxanthine + H2O + oxygen → hydrogen peroxide + 7-methylurate
H2O + (-)-maackiain-3-O-glucoside-6''-malonate → malonate + (-)-maackiain-3-O-glucoside + H+
H2O + carbonyl sulfide → hydrogen sulfide + CO2
Mg2+ + H2O + protoporphyrin IX + ATP → 3 H+ + phosphate + ADP + Mg-protoporphyrin
H2O + L-asparagine + ATP → L-asparagine + phosphate + ADP
H2O + sphingosine 1-phosphate → phosphate + sphingosine
H2O + H+ + (Z)-3-ureidoacrylate peracid → (Z)-3-peroxyaminoacrylate + ammonium + CO2
H2O + GMP → guanosine + phosphate
H2O + (2E,6E)-farnesal + NAD+ → 2 H+ + NADH + (2E,6E)-farnesoate
H2O + (4,5-dihydro-5-oxofuran-2-yl)-acetate → H+ + 3-oxoadipate
2-GDP-[(2S,3S,6R)-5-imino-6-methyloxan-3-ol] + H2O → GDP-4-dehydro-3,6-dideoxy-α-D-mannose + ammonium
H2O + mannopine + ATP → mannopine + phosphate + ADP
H2O + meso-diaminopimelate + ATP → H+ + meso-diaminopimelate + phosphate + ADP
H2O + anguibactin + ATP → anguibactin + phosphate + ADP
2 H+ + (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate ← H2O + isopentenyl diphosphate
H2O + enterobactin + ATP → enterobactin + phosphate + ADP
H2O + L-glutamyl-L-glutamate → 2 L-glutamate
H2O + dihydrophloroglucinol → 3-hydroxy-5-oxohexanoate + H+
H2O + α-D-glucopyranose 1-phosphate → D-Glucose + phosphate
H2O + nicotine-Δ1'5'-iminium ion + oxygen → hydrogen peroxide + cotinine
H2O + D-galactosamine-6-phosphate → D-tagatofuranose 6-phosphate + ammonium
an oxidized electron donor + H2O + carbon monoxide → a reduced electron donor + CO2
H2O + D-myo-inositol (1,2,3,4) tetrakisphosphate → D-myo-inositol (1,2,3) trisphosphate + phosphate
(11Z)-(S)-3-hydroxyhexadec-11-enoyl-CoA ← H2O + (2E,11Z)-hexadec-2,11-dienoyl-CoA
4 porphobilinogen + H2O → 4 ammonium + preuroporphyrinogen
H2O + biuret → urea-1-carboxylate + ammonium
2 H2O + 2 S-adenosyl-L-methionine + 12,18-didecarboxysiroheme → 2 propanoate + 2 H+ + 2 5'-deoxyadenosine + 2 L-methionine + pre-heme d1
H2O + 4-(6-hydroxy-pyridin-3-yl)-4-oxobutanal + NADP+ → 2 H+ + 6-hydroxy-3-succinoyl-pyridine + NADPH
H2O + 3-phosphonopyruvate + acetyl-CoA → coenzyme A + (R)-2-(phosphomethyl)malate + H+
H2O + NAD(P)+ + (2R,4S)-2, 4-diaminopentanoate → (2R)-2-amino-4-oxopentanoate + NAD(P)H + H+ + ammonium
H2O + α-tomatine → tomatidine + lycotetraose
H2O + (S)-methylmalonyl-CoA → coenzyme A + methylmalonate + H+
2 a peptidoglycan dimer (E. faeciums) + 3 H2O → 4 D-alanine + a peptidoglycan tetramer with a D,D cross-link (Enterococcus faecium) + di-trans,octa-cis-undecaprenyl diphosphate + H+
H2O + NADP+ + gentisaldehyde → 2 H+ + NADPH + gentisate
H2O + L-glutamine + ATP → 2 H+ + N5-phospho-L-glutamine + phosphate + AMP
4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + H2O → N-acetyl-β-D-galactosamine + 5-dehydro-4-deoxy-D-glucuronate
H2O + 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate → 2-oxopent-4-enoate + H+ + benzoate
H2O + 5,10-methenyltetrahydrofolate mono-L-glutamate → H+ + (6S)-5-formyl-tetrahydrofolate mono-L-glutamate
H2O + [(3S)-4-octanoyl-5-oxooxolan-3-yl]methyl phosphate → SCB2 butanolide intermediate + phosphate
L-carnitine + H2O + ATP → L-carnitine + phosphate + ADP
H2O + D-myo-inositol (1,2,3,6) tetrakisphosphate → D-myo-inositol (1,2,3) trisphosphate + phosphate
H2O + D-myo-inositol (2,5) bisphosphate → 1D-myo-inositol 2-monophosphate + phosphate
H2O + phorbol 12,13-dibutanoate → phorbol 13-butanoate + butanoate + H+
H2O + S-(hercyn-2-yl)-L-cysteine S-oxide → pyruvate + ammonium + 2-(hydroxysulfanyl)hercynine
H2O + UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine → acetate + UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine
H2O + (24E)-3α,7α-dihydroxy-5β-cholest-24-enoyl-CoA → (24R,25R)-3α,7α,24-trihydroxy-5β-cholestanoyl CoA
H2O + NADP+ + 22-oxo-docosanoate → 2 H+ + NADPH + docosanedioate
H2O + D-myo-inositol (1,3,4)-trisphosphate → D-myo-inositol (1,3)-bisphosphate + phosphate
H2O + L-methionine → 2-oxobutanoate + methanethiol + ammonium
H2O + formyl-L-isoglutamine → formate + L-isoglutamine
H2O + (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA → coenzyme A + (7Z,10Z,13Z,16Z,19Z)-docosa-7,10,13,16,19-pentenoate + H+
H2O + trans-zeatin riboside diphosphate → trans-zeatin riboside monophosphate + H+ + phosphate
H2O + dodecanal + NAD+ → 2 H+ + NADH + laurate
H2O + palmitaldehyde + NAD+ → 2 H+ + NADH + palmitate
H2O + NAD+ + 3-oxo-24-ethyl-26-al-cholest-4-ene → 2 H+ + NADH + 3-oxo-24-ethyl-cholest-4-en-26-oate
H2O + (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA → (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate + coenzyme A + H+
(13E)-8α-hydroxylabd-13-en-15-yl diphosphate + H2O → labdenediol + diphosphate
H2O + pimeloyl-CoA → 3-hydroxypimeloyl-CoA
H2O + D-firefly luciferyl-CoA → coenzyme A + D-firefly luciferin + H+
phylloquinone + H2O → menadione + phytol
H2O + diisopropyl fluorophosphate → 2 H+ + diisopropyl phosphate + fluoride
H2O + D-myo-inositol (1,2,3,4,5)-pentakisphosphate → D-myo-inositol (2,3,4,5) tetrakisphosphate + phosphate
H2O + cis-(homo)3aconitate → (-)threo-iso(homo)3citrate
H2O + O-carbamoyl-L-serine + H+ → 2 ammonium + pyruvate + CO2
H2O + β-D-cellobiose → 2 β-D-glucopyranose
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)nonan-1-imine → glycine + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)nonan-1-imine
H2O + H+ + Fe3+-[monoglucosyl-(2,3-dihydroxybenzoylserine)3] complex → N-(2,3-dihydroxybenzoyl)-L-serine + Fe3+-[salmochelin S1] complex
an oxidized electron donor + H2O + indole-3-glyoxal → a reduced electron donor + H+ + indole-3-glyoxylate
2 H2O + ricinine → 3-carboxy-4-methoxy-N-methyl-2-pyridone + ammonium
H2O + (2E,6E)-farnesyl diphosphate → cubebol + diphosphate
H2O + 2'-deoxycytidine 3'-monophosphate → 2'-deoxycytidine + phosphate
(3S)-citramalyl-CoA ← H2O + 3-methylfumaryl-CoA
H2O + P1,P3-bis(5'-adenosyl) triphosphate → 2 H+ + ADP + AMP
H2O + luteolin 7-O-β-D-diglucuronide → luteolin 7-O-β-D-glucuronide + β-D-glucuronate
H2O + all-trans-retinyl palmitate → 11-cis-retinol + palmitate + H+
H2O + (4R,7R)-4-isopropenyl-7-methyloxepan-2-one → H+ + (3R,6R)-6-hydroxy-3-isopropenylheptanoate
H2O + (2E,6E)-farnesyl diphosphate → H+ + (2E,6E)-farnesyl phosphate + phosphate
2-hydroxy-6-oxo-nona-2,4-dienoate + H2O → 2-oxopent-4-enoate + butanoate + H+
H2O + geranylgeranyl diphosphate → cyclooctat-9-en-7-ol + diphosphate
L-arabino-1,4-lactone 5-phosphate + H2O → 5-phospho-L-arabinate + H+
H2O + psilocybin → psilocin + phosphate
H2O + 4-methyl-3-oxoadipate-enol-lactone → H+ + 4-methyl-3-oxoadipate
H2O + dUTP → H+ + phosphate + dUDP
6-oxohexanoate + H2O + NADP+ → 2 H+ + adipate + NADPH
H2O + glyoxal → glycolate + H+
H2O + glycyl-L-aspartate → glycine + L-aspartate
2 H2O + 2 L-glutamine + 2 ATP + Ni-sirohydrochlorin → 2 H+ + 2 L-glutamate + 2 phosphate + 2 ADP + Ni-sirohydrochlorin a,c-diamide
H2O + D-carnitinyl-CoA → coenzyme A + D-carnitine + H+
H2O + methyl β-D-glucoside 6-phosphate → β-D-glucose 6-phosphate + methanol
H2O + 2-sulfanyl-3,4-dihydropyrimidin-4-one → hydrogen sulfide + uracil
H2O + neocarrabiose sulfate → neocarrabiose + H+ + sulfate
H2O + adenosine 2'-monophosphate → adenosine + phosphate
H2O + adenosyl hopane → ribosyl hopane + adenine
H2O + (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran
H2O + ammeline → ammonium + ammelide
H2O + pravastatin lactone → pravastatin acid + H+
3β-hydroxy-15,16-epoxydolabrene + H2O → 3β,15,16-trihydroxydolabrene
phosphoenolpyruvate + H2O + N-acetyl-D-mannosamine 6-phosphate → phosphate + N-acetyl-β-neuraminate 9-phosphate
H2O + 3-oxo-24-(isopropanoyl)-cholest-4,24-dien-26-oyl-CoA → 2 H+ + propanoyl-CoA + 3,24-dioxo-cholest-4-en-26-oate
ent-8α-hydroxylabd-13-en-15-yl diphosphate ← H2O + geranylgeranyl diphosphate
2 H+ + H2O + L-citrulline → L-ornithine + ammonium + CO2
H2O + (R)-adrenaline + oxygen → methylamine + hydrogen peroxide + 3,4-dihydroxyphenylglycolaldehyde
H2O + L-rhamnono-1,4-lactone → L-rhamnonate + H+
H2O + γ-L-glutamyl-(S)-trans-1-propenyl-L-cysteine → S-trans-1-propenyl-L-cysteine + L-glutamate
H2O + NAD+ + L-lysine → (S)-2-amino-6-oxohexanoate + NADH + H+ + ammonium
H2O + Coα-[α-(5-methoxy-6-methylbenzimidazolyl)]-Coβ-adenosylcobamide 5'-phosphate → Coα-[α-(5-methoxy-6-methyl-benzimidazolyl)]-Coβ-adenosylcobamide + phosphate
H2O + maltose → β-D-glucopyranose + α-D-glucopyranose
H2O + phosphate + ATP → 2 phosphate + H+ + ADP
H2O + AAI-1 → H+ + N-(3-oxooctanoyl)-L-homoserine
H2O + 3-aminotridec-2-en-4-one → tridecane-3,4-dione + ammonium
H2O + R-vicianin → vicianose + (R)-mandelonitrile
H2O + 3-fumarylpyruvate → pyruvate + H+ + fumarate
H2O + benzaldehyde + NADP+ → 2 H+ + NADPH + benzoate
H2O + sarcosine + oxygen → glycine + hydrogen peroxide + formaldehyde
H2O + 4-imidazolone-5-propanoate + oxygen → hydrogen peroxide + hydantoin-5-propanoate
H2O + glutarate semialdehyde + NAD+ → 2 H+ + glutarate + NADH
3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA ← H2O + 3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA
H2O + (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + ATP → (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + phosphate + ADP
phosphoenolpyruvate + H2O + D-arabinofuranose 5-phosphate → 3-deoxy-D-manno-octulosonate 8-phosphate + phosphate
H2O + N,N'-diacetylchitobiose 6'-phosphate → acetate + N-monoacetylchitobiose 6'-phosphate
H2O + α-lactose → β-D-galactopyranose + β-D-glucopyranose
H2O + N-acetylphosphinothricyl-L-alanyl-L-leucine → acetate + phosalacine
H2O + S-bimane-L-cysteinylglycine → glycine + [Cys]-S-bimane
2 H2O + 4-hydroxyacetophenone + ATP + CO2 → 2 phosphate + 3 H+ + 4-hydroxybenzoyl-acetate + AMP
H2O + thiocyanate → cyanate + hydrogen sulfide
H2O + chlorzoxazone → 2-amino-5-chlorophenyl carbonate + H+
2 H2O + dTTP → 2 H+ + 2 phosphate + dTMP
FAD + (R)-β-hydroxy-L-kynurenine + H2O → FADH2 + (2S,3R)-2-[(2-aminophenyl)amino]-3-carboxy-3-hydroxypropanoate + H+
D-xylono-1,4-lactone + H2O → D-xylonate + H+
2 NAD+ + H2O + (2R)-3-sulfopropanediol → 2 NADH + 3 H+ + (2R)-3-sulfolactate
H2O + UMP → uridine + phosphate
H2O + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine → 2 H+ + UMP + lipid X
2 Fe2+ + 2 H2O + hydrogen peroxide → 2 [FeO(OH)] monomer + 4 H+
H2O + 3-ureidoacrylate → aminoacrylate + H+ + carbamate
H2O + parathion + ATP → parathion + phosphate + ADP
an oxidized electron donor + H2O + (indol-3-yl)acetate → a reduced electron donor + 2-oxoindole-3-acetate
H2O + 4-nitrobenzaldehyde + NAD+ → 2 H+ + NADH + 4-nitrobenzoate
H2O + N5-phenyl-L-glutamine → aniline + H+ + L-glutamate
H2O + 1-palmitoyl-sn-glycerol 3-phosphate → 1-palmitoyl-sn-glycerol + phosphate
H2O + 5'-dehydroadenosine + oxygen → hydrogen peroxide + H+ + adenin-9-yl riburonosate
H2O + succinyl-CoA → coenzyme A + H+ + succinate
H2O + propane-1,3-diamine + oxygen → hydrogen peroxide + 3-aminopropanal + ammonium
H2O + N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + L-glutamine + ATP → 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine + H+ + L-glutamate + phosphate + ADP
H2O + glycyl-L-asparagine → glycine + L-asparagine
H2O + ATP + guanine → H+ + phosphate + ADP + guanine
H2O + 2-oxoglutaryl-CoA → coenzyme A + 2-oxoglutarate + H+
(E)-cinnamoyl-CoA + H2O → 3-hydroxy-3-phenylpropanoyl-CoA
H2O + aclacinomycin T → methanol + H+ + 15-demethoxyaclacinomycin T
H2O + S-(2-chlorocarboxymethyl)-glutathione → glyoxylate + H+ + glutathione + chloride
H2O + 2-phospho-D-glycerate → (R)-glycerate + phosphate
H2O + H+ + guanine → xanthine + ammonium
2 oxygen + thiamine + H2O → 2 hydrogen peroxide + H+ + thiamine acetate
H2O + validoxylamine A 7'-phosphate → validoxylamine A + phosphate
H2O + 3-phospho-D-glycerate → (R)-glycerate + phosphate
H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)nonan-1-imine → pyruvate + (E)-ω-(methylsulfanyl)nonyl-thiohydroximate + ammonium
pppGpp + H2O → H+ + diphosphate + GTP
H2O + Coα-[α-(benzimidazolyl)]-Coβ-adenosylcobamide 5'-phosphate → Coα-[α-(benzimidazolyl)]-Coβ-adenosylcobamide + phosphate
H2O + N-ethylglycine + oxygen → hydrogen peroxide + ethylamine + glyoxylate
H2O + NAD+ → 2 H+ + β-nicotinamide D-ribonucleotide + AMP
H2O + UDP-N-acetyl-α-D-glucosamine → N-acetyl-β-D-mannosamine + H+ + UDP
sn-glycero-3-phosphocholine + H2O → phosphocholine + glycerol + H+
H2O + 2-pyrone-4,6-dicarboxylate → (1Z,3Z)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate + H+
H2O + 2-oleoylglycerol → oleate + glycerol + H+
H2O + L-saccharopine + NAD+ → (S)-2-amino-6-oxohexanoate + NADH + H+ + L-glutamate
H2O + NAD(P)+ + 2,5-dioxopentanoate → 2 H+ + NAD(P)H + 2-oxoglutarate
H2O + sphinganine 1-phosphate → D-erythro-sphinganine + phosphate
H2O + (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate → 2-oxopent-4-enoate + formate + H+
H2O + premithramycin B lactone → mithramycin DK + CO2
H2O + pyrithiamine → 2 H+ + 4-amino-2-methyl-5-pyrimidinemethanol + 2-(2-methylpyridin-3-yl)ethanol
3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA ← H2O + (E)-4-coumaroyl-CoA
H2O + 1-octanal + NAD+ → 2 H+ + NADH + octanoate
H2O + 5,6-epoxy,18R-hydroxy-icosapentaenoate → resolvin E1
H2O + methyl acetate → acetate + methanol + H+
(2Z,2E)-2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate + H2O → 2,3-dihydroxybenzoate + H+ + (2Z)-2-hydroxypenta-2,4-dienoate
H2O + palmitoleoyl-CoA → coenzyme A + palmitoleate + H+
H2O + uridine 2'3'-cyclic monophosphate → H+ + uridine 3'-monophosphate
H2O + dTTP → H+ + diphosphate + dTMP
H2O + isopenicillin N + phenylacetyl-CoA → coenzyme A + penicillin G + L-2-aminoadipate + H+
maltotetraose + H2O + ATP → maltotetraose + H+ + phosphate + ADP
H2O + S-adenosyl-L-methionine + (31R)-8-ethyl-12-methylbacteriochlorophyllide c → H+ + 5'-deoxyadenosine + L-methionine + (31R)-8-ethyl-71-12-methylbacteriochlorophyllide c
H2O + 2-phenylethanol + ATP → 2-phenylethanol + phosphate + ADP
H2O + 6-acetyl-D-glucose → acetate + H+ + β-D-glucopyranose
H2O + 13-[O(2')-β-D-glucopyranosyl-β-D-glucopyranosyloxy]docosanoate O(6'')-acetate → acetate + sophorosyloxydocosanoate + H+
3,5-dihydroxy-1,4-naphthoquinol + H2O + oxygen → 2 H+ + 2,3-dihydroxybenzoate + pyruvate
glyphosate + H2O + oxygen → (aminomethyl)phosphonate + hydrogen peroxide + glyoxylate
H2O + dCTP → H+ + phosphate + dCDP
H2O + [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol 5'-phosphate → [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol + phosphate
H2O + O-orsellinate depside → 2 orsellinate + H+
H2O + L-alanine + ATP → L-alanine + phosphate + ADP
H2O + butachlor → butan-1-ol + 2-chloro-N-(2,6-diethylphenyl)-N-hydroxymethylacetamide
H2O + 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + NAD+ → 2 H+ + 3-hydroxy-2-methylpyridine-4,5-dicarboxylate + NADH
H2O + ATP + carbon monoxide → phosphate + ADP + carbon monoxide
H2O + glycochenodeoxycholate → glycine + chenodeoxycholate
H2O + N-acetyl-β-neuraminate 9-phosphate → N-acetyl-β-neuraminate + phosphate
H2O + vibriobactin + ATP → vibriobactin + phosphate + ADP
H2O + L-histidine + ATP → L-histidine + phosphate + ADP
H2O + 3-phenyl-2-oxopropanoate + acetyl-CoA → coenzyme A + 2-benzyl-2-hydroxybutanedioate + H+
H2O + caffeine + oxygen → hydrogen peroxide + 1,3,7-trimethylurate
5-chloro-2-methyl-dienelactone + H2O → 5-chloro-2-methyl-maleylacetate + H+
H2O + NAD+ + (R)-lactaldehyde → 2 H+ + NADH + (R)-lactate
H2O + S-adenosyl-L-methionine → adenosine + H+ + L-methionine
H2O + 6-amino-6-deoxyfutalosine → dehypoxanthine futalosine + adenine
H2O + (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1 (10),2-dien-4-oate → (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + H+
Mg2+ + H2O + ATP → Mg2+ + H+ + phosphate + ADP
H2O + cyclic ADP-ribose → 3 H+ + 1-(5-phospho-β-D-ribosyl)-AMP
H2O + glutathione → L-cysteinylglycine + L-glutamate
H2O + 3-(glutathion-S-yl)-3-methylhexan-1-ol + ATP → H+ + 3-(glutathion-S-yl)-3-methylhexan-1-ol + phosphate + ADP
17(E)-cheilanthenediol ← H2O + all-trans-geranylfarnesol
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-2-(4-hydroxyphenyl)ethan-1-imine → glycine + (E)-1-(L-cystein-S-yl)-N-hydroxy-2-(4-hydroxyphenyl)ethan-1-imine
an oxidized electron donor + H2O + D-glyceraldehyde → (R)-glycerate + a reduced electron donor + H+
H2O + 3-(4-deoxy-β-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine → 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-β-D-glucosamine
H2O + rhodomycinone D → methanol + H+ + 10-carboxy-3-deoxycarminomycin
H2O + leukotriene A4 → leukotriene B4
eugenol O-β-D-xylopyranosyl-(1->6)-O-β-D-glucopyranoside + H2O → primeverose + eugenol
H2O + oxygen + metanephrine → methylamine + hydrogen peroxide + 3-methoxy-4-hydroxyphenylglycolaldehyde
3-(3,4-dihydroxyphenyl)-3-hydroxypropanoate ← H2O + trans-caffeoyl-CoA
H2O + carnosine → β-alanine + L-histidine
H2O + stachyose → α-D-galactopyranose + raffinose
H2O + D-mannitol 1-phosphate → phosphate + D-mannitol
H2O + GDP → H+ + phosphate + GMP
H2O + dATP + ATP → phosphate + ADP + dATP
2 oxygen + 4 Mn2+ + 4 H2O → 4 MnIVO2 + 8 H+
H2O + L-methionine + ATP → S-adenosyl-L-methionine + diphosphate + phosphate
GDP-α-D-mannose + H2O → 2 H+ + GMP + α-D-mannose 1-phosphate
H2O + pyridoxine 5'-phosphate → pyridoxine + phosphate
(3R)-3-hydroxybutanoyl-CoA + H2O → coenzyme A + (R)-3-hydroxybutanoate + H+
H2O + geranylgeranyl diphosphate → (6E,10E)-geranyllinalool + diphosphate
H2O + cyanate + ATP → cyanate + phosphate + ADP
fluoroacetate + H2O → glycolate + H+ + fluoride
H2O + α-tomatine → β-D-glucopyranose + β2-tomatine
H2O + CTP → CMP + H+ + diphosphate
H2O + (5R,7aS)-7a-methyl-1,5-dioxo-3,5,6,7-tetrahydro-2H-indene-4-carboxyl-CoA → H+ + (3R)-2-(2-carboxyethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA
H2O + 22-oxo-docosanoyl-CoA + NADP+ → 2 H+ + NADPH + 22-carboxy-docosanoyl-CoA
H2O + glycerol + ATP → glycerol + phosphate + ADP
H2O + selenite + ATP → H+ + phosphate + selenite + ADP
monocyclic sesterterpenediol ← H2O + all-trans-geranylfarnesol
H2O + taurochenodeoxycholate → taurine + chenodeoxycholate
H2O + 1-nitrobiuret → 1-carboxynitrourea + ammonium
scalarane-17α-19-diol ← H2O + all-trans-geranylfarnesol
H2O + β1-tomatine → β-D-glucopyranose + γ-tomatine
14βH-scalarane-17α-19-diol ← H2O + all-trans-geranylfarnesol
H2O + UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-gulopyranose → 2,4-diacetamido-2,4,6-trideoxy-β-L-gulopyranose + H+ + UDP
H2O + ATP + an amino acid → phosphate + ADP + an amino acid
5-phospho-α-D-ribose 1-diphosphate + H2O → α-D-ribose 1,5-bisphosphate + H+ + phosphate
H2O + ectoine + ATP → ectoine + phosphate + ADP
H2O + N-formyldemecolcine → formate + demecolcine
H2O + α-lactose 6'-phosphate → α-D-galactose 6-phosphate + β-D-glucopyranose
benzyl alcohol 6-O-β-D-xylopyranosyl-β-D-glucopyranoside + H2O → primeverose + benzyl alcohol
H2O + NAD+ + L-isoleucine → NADH + (S)-3-methyl-2-oxopentanoate + H+ + ammonium
H2O + a reduced electron donor + L-sorbosone 2,6-lactone → an oxidized electron donor + 2-keto-D-gluconate
H2O + 4-(methylsulfanyl)-2-oxobutanoate + acetyl-CoA → coenzyme A + 2-[(2'-methylsulfanyl)ethyl]malate + H+
H2O + N-acetyl-L,L-2,6-diaminopimelate → acetate + L,L-diaminopimelate
H2O + 6-phospho D-glucono-1,5-lactone → D-gluconate 6-phosphate + H+
H2O + (S)-malyl-CoA → coenzyme A + (S)-malate + H+
H2O + L-lysine + oxygen → (S)-2-amino-6-oxohexanoate + hydrogen peroxide + ammonium
2-chloro-cis-dienelactone + H2O → 2-chloromaleylacetate + H+
an oxidized electron donor + H2O + (4S)-limonene → (4S)-perillyl alcohol + a reduced electron donor
H2O + succinate semialdehyde + NADP+ → 2 H+ + NADPH + succinate
H2O + β-nicotinate D-ribonucleotide → β-D-ribosylnicotinate + phosphate
H2O + cytidine 2',3'-cyclic monophosphate → H+ + cytidine-3'-monophosphate
18-hydroxyrenierapurpurin + H2O → 5 H+ + χ,χ-caroten-18-oate
H2O + 6-aminohexanoate linear dimer → 2 6-aminohexanoate
an oxidized electron donor + H2O + N,N-dimethylglycine → a reduced electron donor + formaldehyde + sarcosine
H2O + P1,P5-bis(5'-adenosyl) pentaphosphate → 2 H+ + ADP + ATP
H2O + dGTP → H+ + phosphate + dGDP
H2O + trehalose-trans-keto-mono-mycolate + ATP → H+ + trehalose-trans-keto-mono-mycolate + phosphate + ADP
H2O + (+)-(1S,4R)-limonene-1,2- epoxide → (1S,2S,4R)-limonene-1,2-diol
H2O + glorin → ethanol + H+ + N-propanoyl-γ-L-glutamyl-L-orornithine-δ-lactam
χ,χ-caroten-18-oate + H2O → 2 H+ + 18'-hydroxy-χ,χ-caroten-18-oate
an oxidized electron donor + H2O + (+)-6-hydroxypinoresinol → 4-(4-hydroxy-3-methoxyphenyl)-tetrahydro-3H-furo[3,4-c]furan-1-one + a reduced electron donor + 2-methoxyhydroquinone
H2O + (E)-1-(L-cysteinylglycin-S-yl)-N-hydroxy-ω-(methylsulfanyl)heptan-1-imine → L-seryl-glycine + (E)-ω-(methylsulfanyl)heptyl-thiohydroximate
H2O + 3-(glutathion-S-yl)-hexan-1-ol → L-glutamate + S-(1-hydroxyhexan-3-yl)-L-cysteinylglycine
H2O + (2E)-7-carboxy-4-methyl-5-oxohept-2-enoyl-CoA → (3R)-7-carboxy-3-hydroxy-4-methyl-5-oxoheptanoyl-CoA
H2O + malonylgenistin → malonate + H+ + genistin
H2O + 5-(methylsulfanyl)-2,3-dioxopentyl 1-phosphate → 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + H+ + phosphate
2 ATP + H2O + N1-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine → 2 H+ + 2 phosphate + 2 ADP + aerobactin
H2O + β-homovaline-β-homoalanine-β-homoleucine → L-β-homoalanyl-L-β-homoleucine + (3R)-β-leucine
H2O + core oligosaccharide-lipid A (E. coli K-12 core type) + ATP → H+ + core oligosaccharide-lipid A (E. coli K-12 core type) + phosphate + ADP
H2O + H+ + 2-hexaprenyl-6-methoxyaminophenol → 2-methoxy-6-all trans-hexaprenyl-1,4-benzoquinol + ammonium
H2O + 4-deoxy-β-D-gluc-4-enuronosyl-(1,4)-N-acetyl-D-galactosamine → N-acetyl-α-D-galactosamine + 4-deoxy-L-threo-hex-4-enopyranuronate
H2O + (2E,11Z)-octadecenoyl-CoA → (S)-3-hydroxy-(11Z)-octadecenoyl-CoA
H2O + juvenile hormone III → juvenile hormone III acid + methanol + H+
H2O + 1,2-dichloroethane → 2-chloroethanol + H+ + chloride
ATP + L-arginine + H2O → ADP + phosphate + L-arginine + H+
9-cis-retinal + NAD+ + H2O → 9-cis-retinoate + NADH + 2 H+
lavandulyl diphosphate + H2O → lavandulol + diphosphate
picolinate + H2O + an oxidized unknown electron carrier → 6-hydroxypicolinate + a reduced unknown two electron carrier
chlorpyrifos + H2O → 3,5,6-trichloro-2-pyridinol + diethylthiophosphate + H+
isoproturon + H2O + H+ → dimethylamine + CO2 + 4-(propan-2-yl)aniline
ATP + L-aspartate + H2O → ADP + L-aspartate + phosphate + H+
(S)-3-hydroxydodecanoyl-CoA ← (2E)-dodec-2-enoyl-CoA + H2O
(S)-4-hydroxy-2-oxohexanoate ← (2Z)-2-hydroxyhexa-2,5-dienoate + H2O
ATP + putrescine + H2O → ADP + putrescine + phosphate + H+
1-methyl-2-oxoimidazolidine-4-carboxylate + H2O → (2S)-2-(carboxyamino)-3-(methylamino)propanoate + H+
18-oxo-oleate + NADP+ + H2O → α,ω-9Z-octadecenedioate + NADPH + 2 H+
CMP + H2O → cytosine + D-ribofuranose 5-phosphate
(S)-piperidine-2-carboxamide + H2O → L-pipecolate + ammonium
Ni2+ + ATP + H2O → Ni2+ + ADP + phosphate + H+
α,α-trehalose + H2O + ATP → α,α-trehalose + phosphate + ADP + H+
ATP + L-cysteine + H2O → ADP + L-cysteine + phosphate + H+
ginsenoside Rd + H2O → (20S)-ginsenoside Rg3 + D-glucopyranose
monuron + H2O + H+ → dimethylamine + CO2 + 4-chloroaniline
p-nitrophenyl-β-D-glucopyranoside + H2O → 4-nitrophenol + D-glucopyranose + H+
linoleoyl ethanolamide + H2O → linoleate + ethanolamine
6-O-methyl-N-deacetylisoipecoside + H2O → 6-O-methyl-N-deacetylisoipecoside aglycon + D-glucopyranose
κ-carrageenose + n H2O → n neocarrabiose sulfate + n neocarratetraose 4-O-disulfate
oleuropein + H2O → oleuropein aglycone + D-glucopyranose
protodioscin + H2O → 26-degluco-protodioscin + D-glucopyranose
diazinon + H2O → 2-isopropyl-6-methylpyrimidin-4-ol + diethylthiophosphate + H+
ATP + H2O + L-tyrosine → ADP + phosphate + L-tyrosine + H+
N,N'-diacetylchitobiose + H2O → 2 N-acetyl-D-glucosamine
α-D-galactose 1-phosphate + H2O → D-galactopyranose + phosphate
2'-deoxyadenosine + H2O → adenine + 2-deoxy-D-ribose
N-sulfo-D-glucosamine + H2O → D-glucosamine + sulfate
ginsenoside Rc + H2O → ginsenoside C-Mc1 + D-glucopyranose
daphnin + H2O → daphnetin + D-glucopyranose
ATP + cob(I)alamin + H2O → adenosylcobalamin + diphosphate + phosphate
[(4-D-Ala)-(2-GlcNAc)-Rib-ol-P]n-Gro-P-Gro-P-β-D-ManNAc-(1→4)-α-D-GlcNAc-P-peptidoglycan + n H2O → [(2-GlcNAc)-Rib-ol-P]n-Gro-P-Gro-P-β-D-ManNAc-(1→4)-α-D-GlcNAc-PP-peptidoglycan + n D-alanine + n H+
linustatin + H2O → 2-hydroxy-2-methylpropanenitrile + gentiobiose
biochanin A-7-O-glucoside + H2O → biochanin-A + D-glucopyranose + H+
Fe3+ + ATP + H2O → Fe3+ + ADP + phosphate + H+
inosine + H2O → D-ribofuranose + hypoxanthine
H2O + D-ribofuranose 2,5-bisphosphate → D-ribofuranose 5-phosphate + phosphate
raucaffricine + H2O → vomilenine + D-glucopyranose
4-nitrophenyl palmitate + H2O → 4-nitrophenol + palmitate + 2 H+
dalcochinin-8'-O-β-glucoside + H2O → dalcochinin + D-glucopyranose
ATP + H2O + D-xylose → ADP + phosphate + H+ + D-xylose
limonene + H2O + an oxidized unknown electron carrier → perillyl alcohol + a reduced unknown two electron carrier
ginsenoside F2 + H2O → ginsenoside C-K + D-glucopyranose
pullulan + n H2O → n+1 panose
Zn2+ + ATP + H2O → Zn2+ + ADP + phosphate + H+
cytidine + H2O → D-ribofuranose + cytosine
cellobiosan + H2O → levoglucosan + D-glucopyranose
poly-3-hydroxyoctanoate + H2O → poly-3-hydroxyoctanoate
vernolate + H2O → (9Z)-12,13-dihydroxyoctadeca-9-enoate
2'-deoxyinosine + H2O → hypoxanthine + 2-deoxy-D-ribose
genistin + H2O → genistein + D-glucopyranose + H+
ATP + molybdate + H2O → ADP + phosphate + molybdate + H+
cichoriin + H2O → esculetin + D-glucopyranose
ochratoxin A + H2O → ochratoxin α + L-phenylalanine
2-phenylethyl β-D-glucopyranoside + H2O → 2-phenylethanol + D-glucopyranose
α-acetyldigitoxin + H2O → digitoxin + acetate + H+
N,N'-diacetylchitobiose + H2O → β-D-glucosaminyl-(1→4)-N-acetyl-D-glucosamine + acetate
glycine betaine + ATP + H2O → glycine betaine + phosphate + H+ + ADP
D-selenomethionine + ATP + H2O → D-selenomethionine + ADP + phosphate + H+
ATP + [6-O-phospho-α-glucan] + H2O → 3-O-phospho-[6-O-phospho-α-glucan] + AMP + phosphate + 2 H+
ginsenoside Rd + H2O → ginsenoside F2 + D-glucopyranose
tauroursodeoxycholate + H2O → ursodeoxycholate + taurine
4-deoxy-β-L-erythro-hex-4-enopyranuronosyl-(1,4)-D-N-sulfoglucosamine + H2O → N-sulfo-D-glucosamine + 4-deoxy-L-threo-hex-4-enopyranuronate
2 H2O + (indole-3-yl)acetonitrile → ammonium + (indol-3-yl)acetate
2 H2O + 6-oxo-1,4,5,6-tetrahydronicotinate → (S)-2-formylglutarate + ammonium
H2O + glycine + oxygen → hydrogen peroxide + glyoxylate + ammonium
H2O + 5-aminopentanamide → 5-aminopentanoate + ammonium
H2O + L-cysteate → pyruvate + H+ + ammonium + sulfite
H2O + 1-aminocyclopropane-1-carboxylate → 2-oxobutanoate + ammonium
H2O + N-formimino-L-glutamate → ammonium + N-formyl-L-glutamate
H2O + H+ + 1-pyrroline-4-hydroxy-2-carboxylate → 2,5-dioxopentanoate + ammonium
H2O + guanosine + H+ → xanthosine + ammonium
N4-acetylcytidine + H2O → cytidine + acetate + H+
ginsenoside Rf + 2 H2O → protopanaxatriol + 2 D-glucopyranose
2-methylbutanoyl-CoA + H2O → 2-methylbutanoate + coenzyme A + H+
triacetate lactone + H2O → 3,5-dioxohexanoate
D-glucurono-6,3-lactone + H2O → D-glucopyranuronate + H+
2-hydroxy-dADP + H2O → 2-hydroxy-dAMP + phosphate + H+
2-O-(α-D-glucopyranosyl)glycerol + H2O → D-glucopyranose + glycerol
digiproside + H2O → digitoxigenin + D-fucopyranose
2-chloroacetate + H2O → glycolate + H+ + chloride
2 S-adenosyl-L-methionine + H2O + 3-(4-hydroxyphenyl)pyruvate + 5-amino-6-(D-ribitylamino)uracil → 2 5'-deoxyadenosine + 2 L-methionine + 3 H+ + 7,8-didemethyl-8-hydroxy-5-deazariboflavin + ammonium + oxalate
2-oxoadipate + NAD+ + ammonium ← 2 H+ + H2O + NADH + (2Z,4E)-2-aminomuconate
H2O + L-cysteine → pyruvate + ammonium + hydrogen sulfide
H2O + 2-iminoacetate + H+ → glyoxylate + ammonium
H2O + NAD+ + L-alanine → NADH + pyruvate + H+ + ammonium
salinisporamycin A + H2O → saliniketal A + 2,6,8-trihydroxy-7-methylnaphthalene-1,4-dione
methylmalonate semialdehyde + coenzyme A + NAD+ + H2O → propanoyl-CoA + hydrogencarbonate + NADH + H+
D-apionolactone + H2O → D-apionate + H+
β-D-glucopyranosyl abscisate + H2O → 2-cis-abscisate + D-glucopyranose + H+
feruloyl-CoA + H2O → vanillin + acetyl-CoA
maltose + H2O → 2 D-glucopyranose
H2O + purine + NAD+ → 2 H+ + 8-hydroxypurine + NADH
H2O + D-Glucurono-6,2-lactone → D-glucopyranuronate + H+
feruloylacetyl-CoA + H2O → feruloyl diketide + coenzyme A + H+
1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-biphosphate + H2O → 1-stearoyl-2-arachidonoyl-sn-glycerol + D-myo-inositol (1,4,5)-trisphosphate + H+
purpurea glycoside A + H2O → digitoxin + D-glucopyranose
stearoyl ethanolamide + H2O → stearate + ethanolamine
2 (E)-4-coumaroyl-CoA + H2O + H+ + malonyl-CoA → 2 CO2 + 3 coenzyme A + bisdemethoxycurcumin
H2O + 3-methyl-2-oxobutanoate + acetyl-CoA → coenzyme A + (2S)-2-isopropylmalate + H+
H2O + adenosine 3',5'-bisphosphate → phosphate + AMP
H2O + cyclic-AMP → H+ + AMP
H2O + cyclic-GMP → H+ + GMP
5-(methylsulfanyl)-2,3-dioxopentyl 1-phosphate + 3 H2O → 4-(methylsulfanyl)-2-oxobutanoate + formate + 6 H+ + phosphate
3-methyl-2-oxobutanoate + acetyl-CoA + H2O → (2R,3S)-3-isopropylmalate + coenzyme A + H+
3-methyl-2-oxobutanoate + acetyl-CoA + H2O → coenzyme A + H+ + (2R,3S)-3-isopropylmalate
3',5'-Cyclic dAMP + H2O → dAMP + H+
cyclic-IMP + H2O → H+ + IMP
cyclic 3',5'-cytidine monophosphate + H2O → CMP + H+
H2O + (indol-3-yl)acetaldehyde + NADP+ → 2 H+ + (indol-3-yl)acetate + NADPH
7,8-dihydroneopterin 3'-triphosphate + 3 H2O → 7,8-dihydroneopterin + 2 H+ + 3 phosphate
H2O + diphosphate → 2 phosphate + H+
H2O + spermidine + ubiquinone-6 → 4-aminobutanal + propane-1,3-diamine + ubiquinol-6
glycogen + H2O → D-Glucose
H2O + α,α-trehalose → 2 D-Glucose
H2O + octanoyl-CoA → coenzyme A + H+ + octanoate
chitin + H2O → acetate + chitosan + H+
1,3-β-D-glucan + H2O → D-Glucose
8 coenzyme A + 8 H2O + 8 NAD+ + 6 oxygen + 9-octadecynoyl-CoA → 9 acetyl-CoA + 8 H+ + 6 hydrogen peroxide + 8 NADH
H2O + phosphatidate → phosphate + a diglyceride
H2O + phosphatidate → phosphate + a diglyceride
5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + 3 H2O → 6 H+ + D-myo-inositol 1,3,4,5,6-pentakisphosphate + 3 phosphate
H2O + 1-acylglycerophosphocholine → H+ + sn-glycero-3-phosphocholine + fatty acid
H2O + phosphatidylethanolamine → H+ + fatty acid + 1-acylglycerophosphoethanolamine
H2O + 1-acylglycerophosphoethanolamine → H+ + sn-glycero-3-phosphoethanolamine + fatty acid
H2O + phosphatidyl-L-serine → H+ + fatty acid + 1-acylglycerophosphoserine
H2O + 1-acylglycerophosphoserine → H+ + glycerophosphoserine + fatty acid
H2O + a 1-phosphatidyl-1D-myo-inositol → H+ + fatty acid + 2-lysophosphatidyl-D-myo-inositol
H2O + 2-lysophosphatidyl-D-myo-inositol → H+ + sn-glycero-3-phospho-1-inositol + fatty acid
H2O + a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate → H+ + D-myo-inositol (1,4,5)-trisphosphate + a diglyceride
H2O + mannosylinositol phosphorylceramide A (C24) → N-(tetracosanoyl)-sphinganine + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphorylceramide A (C26) → ceramide-1 (C26) + mannose-1D-myo-inositol 1-phosphate
H2O + sn-glycero-3-phosphocholine → choline + glycerol 2-phosphate + H+
H2O + mannosylinositol phosphorylceramide C (C24) → N-(2-hydroxytetracosanoyl)-phytosphingosine + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphorylceramide C (C26) → N-(2-hydroxyhexacosanoyl)-phytosphingosine + mannose-1D-myo-inositol 1-phosphate
H2O + inositol phosphomannosylinositol phosphoceramide A (C24) → N-(tetracosanoyl)-sphinganine + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide A (C26) → ceramide-1 (C26) + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide B' (C24) → N-(2-hydroxytetracosanoyl)-sphinganine + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide B' (C26) → ceramide-2' (C26) + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide B (C24) → N-(lignoceroyl)-phytosphingosine + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide B (C26) → N-(hexacosanoyl)-phytosphingosine + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide C (C24) → N-(2-hydroxytetracosanoyl)-phytosphingosine + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide C (C26) → N-(2-hydroxyhexacosanoyl)-phytosphingosine + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide D (C24) → ceramide-4 (C24) + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide D (C26) → ceramide-4 (C26) + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol-P-ceramide A (C24) → 1D-myo-inositol 3-monophosphate + N-(tetracosanoyl)-sphinganine
H2O + inositol phosphoceramide A (C26) → 1D-myo-inositol 3-monophosphate + ceramide-1 (C26)
H2O + inositol-P-ceramide B' (C24) → 1D-myo-inositol 3-monophosphate + N-(2-hydroxytetracosanoyl)-sphinganine
H2O + inositol phosphoceramide B' (C26) → 1D-myo-inositol 3-monophosphate + ceramide-2' (C26)
H2O + inositol phosphoceramide B (C24) → 1D-myo-inositol 3-monophosphate + N-(lignoceroyl)-phytosphingosine
H2O + inositol-P-ceramide B (C26) → 1D-myo-inositol 3-monophosphate + N-(hexacosanoyl)-phytosphingosine
H2O + inositol phosphoceramide C (C24) → 1D-myo-inositol 3-monophosphate + N-(2-hydroxytetracosanoyl)-phytosphingosine
H2O + inositol phosphoceramide C (C26) → 1D-myo-inositol 3-monophosphate + N-(2-hydroxyhexacosanoyl)-phytosphingosine
H2O + inositol phosphoceramide D (C24) → 1D-myo-inositol 3-monophosphate + ceramide-4 (C24)
H2O + inositol phosphoceramide D (C26) → 1D-myo-inositol 3-monophosphate + ceramide-4 (C26)
H2O + mannosylinositol phosphoceramide B (C24) → N-(lignoceroyl)-phytosphingosine + mannose-1D-myo-inositol 1-phosphate
H2O + Man-β1-6-Ins-1-P-Cer(t20:0/26:0) → N-(hexacosanoyl)-phytosphingosine + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphorylceramide C (C24) → N-(2-hydroxytetracosanoyl)-phytosphingosine + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphorylceramide C (C26) → N-(2-hydroxyhexacosanoyl)-phytosphingosine + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphorylceramide D (C24) → ceramide-4 (C24) + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphorylceramide D (C26) → ceramide-4 (C26) + mannose-1D-myo-inositol 1-phosphate
H2O + inositol phosphomannosylinositol phosphoceramide A (C24) → N-(tetracosanoyl)-sphinganine + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide A (C26) → ceramide-1 (C26) + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide B' (C24) → N-(2-hydroxytetracosanoyl)-sphinganine + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide B' (C26) → ceramide-2' (C26) + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide B (C24) → N-(lignoceroyl)-phytosphingosine + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide B (C26) → N-(hexacosanoyl)-phytosphingosine + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide C (C24) → N-(2-hydroxytetracosanoyl)-phytosphingosine + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide C (C26) → N-(2-hydroxyhexacosanoyl)-phytosphingosine + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide D (C24) → ceramide-4 (C24) + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol phosphomannosylinositol phosphoceramide D (C26) → ceramide-4 (C26) + mannose-(1D-myo-inositol 1-phosphate)2
H2O + inositol-P-ceramide A (C24) → 1D-myo-inositol 1-monophosphate + N-(tetracosanoyl)-sphinganine
H2O + inositol phosphoceramide A (C26) → 1D-myo-inositol 1-monophosphate + ceramide-1 (C26)
H2O + inositol-P-ceramide B' (C24) → 1D-myo-inositol 1-monophosphate + N-(2-hydroxytetracosanoyl)-sphinganine
H2O + inositol phosphoceramide B' (C26) → 1D-myo-inositol 1-monophosphate + ceramide-2' (C26)
H2O + inositol phosphoceramide B (C24) → 1D-myo-inositol 1-monophosphate + N-(lignoceroyl)-phytosphingosine
H2O + inositol-P-ceramide B (C26) → 1D-myo-inositol 1-monophosphate + N-(hexacosanoyl)-phytosphingosine
H2O + inositol phosphoceramide C (C24) → 1D-myo-inositol 1-monophosphate + N-(2-hydroxytetracosanoyl)-phytosphingosine
H2O + inositol phosphoceramide C (C26) → 1D-myo-inositol 1-monophosphate + N-(2-hydroxyhexacosanoyl)-phytosphingosine
H2O + inositol phosphoceramide D (C24) → 1D-myo-inositol 1-monophosphate + ceramide-4 (C24)
H2O + inositol phosphoceramide D (C26) → 1D-myo-inositol 1-monophosphate + ceramide-4 (C26)
H2O + mannosylinositol phosphorylceramide A (C26) → ceramide-1 (C26) + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphoceramide B' (C24) → N-(2-hydroxytetracosanoyl)-sphinganine + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphorylceramide B' (C26) → ceramide-2' (C26) + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphoceramide B' (C24) → N-(2-hydroxytetracosanoyl)-sphinganine + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphorylceramide B' (C26) → ceramide-2' (C26) + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphoceramide B (C24) → N-(lignoceroyl)-phytosphingosine + mannose-1D-myo-inositol 1-phosphate
H2O + Man-β1-6-Ins-1-P-Cer(t20:0/26:0) → N-(hexacosanoyl)-phytosphingosine + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphorylceramide D (C24) → ceramide-4 (C24) + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphorylceramide D (C26) → ceramide-4 (C26) + mannose-1D-myo-inositol 1-phosphate
H2O + mannosylinositol phosphorylceramide A (C24) → N-(tetracosanoyl)-sphinganine + mannose-1D-myo-inositol 1-phosphate
H2O + a phosphatidylcholine → choline + H+ + phosphatidate
5-amino-1-(5-phospho-β-D-ribosyl)imidazole + ATP + CO2 + H2O → ADP + H+ + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate
H2O + oxygen + N1-acetylspermidine → hydrogen peroxide + 3-aminopropanal + N-acetylputrescine
H2O + N-acetyl-D-glucosamine-6-phosphate → acetate + α-D-glucosamine 6-phosphate
2 H2O + thiamine diphosphate → H+ + 2 phosphate + thiamine
ATP + H2O + taurocholate → ADP + H+ + phosphate + taurocholate
H2O + a triglyceride → H+ + fatty acid + a diglyceride
H2O + UDP-α-D-glucose → glycogen + H+ + UDP
H2O + butanoyl-CoA → coenzyme A + H+ + butanoate
H2O + hexanoyl-CoA → coenzyme A + H+ + hexanoate
H2O + trans-2,cis-5-dodecadienoyl-CoA → (R)-3-hydroxy-cis-dodec-5-enoyl-CoA
H2O + trans-2,cis-9-octadecadienoyl-CoA → (R)-3-hydroxy-cis-octadec-9-enoyl-CoA
H2O + (2E,5Z)-tetradecenoyl-CoA → (R)-3-hydroxy-cis-tetradec-5-enoyl-CoA
GTP + H2O → cyclic-GMP + diphosphate + H+
H2O + NAD+ + dodecanal → 2 H+ + NADH + decanoate
H2O + episteryl palmitoleate → H+ + palmitoleate + episterol
ergosteryl palmitoleate + H2O → ergosterol + H+ + palmitoleate
H2O + a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate → D-myo-inositol (1,4,5)-trisphosphate + H+ + a diglyceride
H2O + phosphatidylglycerol → H+ + glycerol 2-phosphate + a diglyceride
H2O + 1-acylglycerophosphocholine → H+ + sn-glycero-3-phosphocholine + fatty acid
H2O + a phosphatidylcholine → H+ + 1-acylglycerophosphocholine + fatty acid
H2O + a 1-phosphatidyl-1D-myo-inositol 3-phosphate → phosphate + a 1-phosphatidyl-1D-myo-inositol
H2O + (2E)-hexadecenoyl-CoA → (S)-3-hydroxyhexacosanoyl-CoA
H2O + trans-hex-2-enoyl-CoA → (R)-3-hydroxyhexanoyl-CoA
H2O + trans-2-icosenoyl-CoA → (R)-3-hydroxyicosanoyl-CoA
H2O + trans-2,cis-9-hexadecadienoyl-CoA → (R)-3-hydroxy-cis-hexadec-9-enoyl-CoA
H2O + trans-2,cis-7-tetradecadienoyl-CoA → (R)-3-hydroxy-cis-tetradec-7-enoyl-CoA
H2O + (2E,7Z)-hexadecadienoyl-CoA → (R)-3-hydroxy-cis-hexadec-7-enoyl-CoA
H2O + (2E)-dodec-2-enoyl-CoA → (R)-3-hydroxylauroyl-CoA
H2O + episteryl oleate → H+ + oleate + episterol
H2O + fecosteryl palmitoleate → fecosterol + H+ + palmitoleate
H2O + fecosteryl oleate → fecosterol + H+ + oleate
H2O + lanosteryl palmitoleate → H+ + palmitoleate + lanosterol
H2O + zymosteryl palmitoleate → H+ + zymosterol + palmitoleate
H2O + zymosteryl oleate → H+ + zymosterol + oleate
H2O + zymosteryl palmitoleate → H+ + zymosterol + palmitoleate
H2O + zymosteryl oleate → H+ + zymosterol + oleate
H2O + uridine → D-ribose + uracil
H2O + 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate → phosphate + phosphatidylglycerol
H2O + cardiolipin → H+ + monolysocardiolipin + fatty acid
H2O + a phosphatidylcholine → H+ + 1-acylglycerophosphocholine + fatty acid
H2O + a 1-phosphatidyl-1D-myo-inositol 4-phosphate → phosphate + a 1-phosphatidyl-1D-myo-inositol
H2O + a 1-phosphatidyl-1D-myo-inositol 4-phosphate → phosphate + a 1-phosphatidyl-1D-myo-inositol
H2O + a 1-phosphatidyl-1D-myo-inositol 4-phosphate → phosphate + a 1-phosphatidyl-1D-myo-inositol
H2O + a 1-phosphatidyl-1D-myo-inositol 4-phosphate → phosphate + a 1-phosphatidyl-1D-myo-inositol
H2O + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate → phosphate + a 1-phosphatidyl-1D-myo-inositol 3-phosphate
H2O + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate → phosphate + a 1-phosphatidyl-1D-myo-inositol 3-phosphate
H2O + a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate → phosphate + a 1-phosphatidyl-1D-myo-inositol 4-phosphate
H2O + a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate → phosphate + a 1-phosphatidyl-1D-myo-inositol 4-phosphate
H2O + a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate → phosphate + a 1-phosphatidyl-1D-myo-inositol 4-phosphate
H2O + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate → phosphate + a 1-phosphatidyl-1D-myo-inositol 3-phosphate
H2O + 1,2-diacylglycerol 3-diphosphate → phosphate + H+ + phosphatidate
H2O + 1,2-diacylglycerol 3-diphosphate → H+ + phosphate + phosphatidate
H2O + a 1-acyl-sn-glycerol 3-phosphate → phosphate + a 1-monoglyceride
H2O + a 1-acyl-sn-glycerol 3-phosphate → phosphate + a 1-monoglyceride
H2O + a 1-acyl-sn-glycerol 3-phosphate → phosphate + a 1-monoglyceride
H2O + a diglyceride → H+ + fatty acid + a 1-monoglyceride
H2O + a diglyceride → H+ + a 1-monoglyceride + fatty acid
H2O + a 1-monoglyceride → H+ + glycerol + fatty acid
H2O + a phosphatidylcholine → H+ + fatty acid + 1-acylglycerophosphocholine
H2O + phosphatidylethanolamine → H+ + fatty acid + 1-acylglycerophosphoethanolamine
H2O + tributyrin → butanoate + dibutyrin
H2O + dibutyrin → butanoate + monobutyrate
H2O + monobutyrate → glycerol + butanoate
5,10-methenyltetrahydrofolate mono-L-glutamate + N1-(5-phospho-β-D-ribosyl)glycinamide + H2O → N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + 2 H+ + 5,6,7,8-tetrahydrofolate
H2O + ADP-D-ribose → AMP + 2 H+ + D-ribose 5-phosphate
NADPH + (E)-5-(methylsulfanyl)pentanal oxime + H+ + L-cysteine + oxygen → 2 H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)pentan-1-imine + NADP+
trihomocitrate → H2O + cis-(homo)3aconitate
a reduced electron donor + ferroheme o + oxygen → an oxidized electron donor + H2O + ferroheme i
NAD(P)H + theophylline + H+ + oxygen → H2O + 1-methylxanthine + NAD(P)+ + formaldehyde
2 H+ + 3 NADH + 3 oxygen + 4,4-dimethyl-5α-cholest-7-en-3β-ol → 3 NAD+ + 4 H2O + 3β-hydroxy-4α-methyl-5α-cholest-7-ene-4β-carboxylate
2-phosphono-formylglycerate → H2O + 1-carboxyvinyl carboxyphosphonate
acetaldehyde + norfuraneol → H2O + (2E)-2-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone
vinblastine + oxygen → 2 H+ + H2O + vincristine
9(S)-HPOTE → H2O + 9,10-epoxy-10,12Z,15Z-octadecatrienoate
NAD(P)H + H+ + (-)-phaseollin + oxygen → H2O + NAD(P)+ + 1α-hydroxy-phaseollone
3 oxygen + 4 catechol → 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O
ammonium + D-glyceraldehyde 3-phosphate + aldehydo-D-ribose 5-phosphate → 4 H2O + pyridoxal 5'-phosphate + H+ + phosphate
2 2,4,6-tribromophenol + 4 a reduced ferredoxin [iron-sulfur] cluster + 5 H+ + oxygen → 2 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + 2,6-dibromo-4-(2,4,6-tribromophenoxy)phenol + bromide
a reduced electron donor + deoxyadlupulone + oxygen → an oxidized electron donor + H2O + adhumulone
a reduced electron donor + L-cysteine + MoO2-molybdopterin cofactor → an oxidized electron donor + H2O + L-alanine + thio-molybdenum cofactor
NAD(P)H + H+ + oxygen + cytoglobosin D → 2 H2O + NAD(P)+ + chaetoglobosin J
deoxymupirocin P → deoxymupirocin C + H2O
2 mycothiol + hydrogen peroxide → 2 H2O + mycothione
2 (1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylate → 2 H+ + H2O + (1R,5aS,6R)-4a-hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate
2 NADPH + 2 H+ + 2 oxygen + L-tryptophan → 2 NADP+ + 3 H2O + (E)-(indol-3-yl)acetaldehyde oxime + CO2
NADPH + H+ + 2-nonaprenylphenol + oxygen → H2O + NADP+ + 2-(all-trans-nonaprenyl)benzene-1,4-diol
2 NADH + 2 H+ + 6-hydroxy-3-succinoyl-pyridine + oxygen → 2 NAD+ + H2O + succinate semialdehyde + 2,5-dihydroxypyridine
3-oxo-5,6-didehydrosuberyl-CoA semialdehyde → H2O + 2-hydroxycyclohepta-1,4,6-triene-1-carboxyl-CoA
L-alanyl-L-valine + (2S,3S,7R)-2,3-diamino-8-(1-carbamoyl-2-iminoimidazolidin-4-yl)-7-hydroxyoctanoate → H2O + 6-dehydroguadinomine B + H+
a reduced electron donor + oxygen + 5,6-dihydroxyindole-2-carboxylate → 2 H2O + an oxidized electron donor + indole-5,6-quinone-2-carboxylate
(S)-N-methylcoclaurine + (R)-N-methylcoclaurine + NADPH + H+ + oxygen → 2 H2O + NADP+ + berbamunine
2 NADPH + 3 H+ + malonyl-CoA + stearidonoyl-CoA → 2 NADP+ + coenzyme A + H2O + (8Z,11Z,14Z,17Z)-icosatetraenoyl-CoA + CO2
NADPH + H+ + oxygen + 20-hydroxy-prefusarin → H2O + NADP+ + 20-hydroxy-13-14 epoxy-prefusarin
thiophene-2-carbonyl-CoA + a reduced electron donor + oxygen → an oxidized electron donor + H2O + 5-hydroxythiophene-2-carbonyl-CoA + H+
NAD(P)H + 2-hydroxylaminobenzoate → anthranilate + H2O + NAD(P)+
5,5-dihydroxy-leucine → 2 H2O + 3-methyl-pyrroline-5-carboxylate + H+
N,N-dihydroxy-L-isoleucine + H+ → H2O + (1E,2S)-2-methylbutanal oxime + CO2
2-oxoglutarate + H+ + oxygen + (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate → 2 CO2 + H2O + succinate + 3-[(E)-2-isocyanoethenyl]-1H-indole
4β-hydroxymethyl-4α-methyl-5α-cholesta-8-en-3β-ol + NADH + H+ + oxygen → 2 H2O + 4β-formyl-4α-methyl-5α-cholesta-8-en-3β-ol + NAD+
NADH + H+ + oxygen + 2-hydroxycanthaxanthin → H2O + NAD+ + 2,2'-dihydroxycanthaxanthin
FADH2 + chloride + oxygen + griseophenone C → 2 H2O + FAD + griseophenone B
2 NADPH + 2 H+ + 2 oxygen + (+)-epi-isozizaene → 2 NADP+ + 3 H2O + albaflavenone
4S-hydroperoxy,17S-hydroxy-docosahexaenoate → H2O + 4(5)-epoxy-17S-hydroxy-docosahexaenoate
4',4'-dihydroxyechinenone → H2O + canthaxanthin
a reduced electron donor + oxygen + indole-3-ethanol → an oxidized electron donor + H2O + indole-3-glycol
D-gluconate → H2O + 2-dehydro-3-deoxy-D-gluconate
NADPH + H+ + versicolorone + oxygen → H2O + NADP+ + versiconol acetate
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-18:2-digalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-18:2-digalactosyldiacylglycerol
H2O + dimethyl sulfoxide + NAD+ ← NADH + dimethyl sulfone + H+
2 glutathione + 3-benzyl-3,6-dihydroxy-6-(hydroxymethyl)-diketopiperazine → 2 H2O + 3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine + ammonium → H2O + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanine
miltiradiene + NADPH + H+ + oxygen → 2 H2O + abietatriene + NADP+
L-arginine + oxygen → H2O + 4-guanidinobutyramide + CO2
NADPH + 2-hydroxycyclohexan-1-one + H+ + oxygen → 6-hydroxyhexan-6-olide + H2O + NADP+
NADPH + H+ + oxygen + notoamide E → H2O + NADP+ + notoamide D
progesterone + a reduced electron donor + oxygen → an oxidized electron donor + H2O + 11α-hydroxyprogesterone
ammonium + phosphoribulosylformimino-AICAR-phosphate → H2O + D-erythro-imidazole-glycerol-phosphate + H+ + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide
NADPH + H+ + 2-decaprenylphenol + oxygen → H2O + NADP+ + 3-(all-trans-decaprenyl)benzene-1,2-diol
2,2',3-trihydroxybiphenyl + NADH + H+ + oxygen → 2,2',3,3'-tetrahydroxybiphenyl + H2O + NAD+
5-chloro-5-deoxy-D-ribonate → H2O + 5-chloro-4-hydroxy-2-oxopentanoate
2 H+ + 2-methoxy-6-(all-trans-nonaprenyl)phenol + oxygen → H2O + 2-methoxy-6-all trans-nonaprenyl-1,4-benzoquinol
2 a reduced electron donor + 2 oxygen + all-trans-4,4'-diaponeurosporene → 2 an oxidized electron donor + 3 H2O + 4,4'-diaponeurosporenal
arachidonate + oxygen → H2O + leukotriene A4
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2'-N-hydroxy-nocardicin c + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 2'-N,N-dihydroxy-nocardicin c
spirilloxanthin + a reduced ferredoxin [iron-sulfur] cluster + oxygen → an oxidized ferredoxin [iron-sulfur] cluster + H2O + 2-oxospirilloxanthin
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + narbomycin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + pikromycin
a reduced electron donor + H+ + oxygen + 15-demethoxy-aclacinomycin A → an oxidized electron donor + H2O + 10-decarboxymethyl, 10-hydroxyaclacinomycin A + CO2
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-oleoyl-2-(3E)-hexadecenoyl-phosphatidylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-linoleoyl-2-(3E)-hexadecenoyl-phosphatidylglycerol
a reduced electron donor + 3,5-dimethylorsellinate + oxygen → an oxidized electron donor + H2O + 4,6-dihydroxy-2-(hydroxymethyl)-3,5-dimethylbenzoate
(methylsulfanyl)lincosamide + 4-propyl-L-proline → H2O + N-demethyllincomycin
2 a reduced electron donor + (1E,6E)-1-(4-hydroxyphenyl)-7-phenylhepta-1,6-diene-3,5-dione → 2 an oxidized electron donor + H2O + (4E,6E)-1-(4-hydroxyphenyl)-7-phenylhepta-4,6-dien-3-one
2 NADPH + 2 S-adenosyl-L-methionine + 2 oxygen + 4-methylsalicylate + H+ + all-trans-hexaprenyl diphosphate → 2 H2O + 2 S-adenosyl-L-homocysteine + 2 NADP+ + 3-demethylubiquinol-6 + diphosphate + CO2
(1R,5aS,6R)-4a-hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate → H2O + (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate
6 glycolate + H+ → 2 succinate + 2 CO2 + 4 H2O + acetate
NADPH + oxygen + (S)-nicotine → H2O + nicotine-1'-N-oxide + NADP+
2 a reduced electron donor + 5S hydro(peroxy),18R-hydroxy-icosapentaenoate + oxygen → 2 an oxidized electron donor + 2 H2O + resolvin E1
L-ornithine + NADPH + 2-oxoglutarate + H+ → H2O + ornaline + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + dihydrorhizobitoxine + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + rhizobitoxine
norsolorinate anthrone + oxygen → H2O + norsolorinate
NADPH + kauralexin A3 + oxygen → H2O + kauralexin A2 + NADP+
2 an oxidized electron donor + 3 H2O + thiosulfate ← 2 a reduced electron donor + 2 sulfite + 3 H+
(S)-3-hydroxyhexanoyl-CoA → H2O + trans-hex-2-enoyl-CoA
17 NADPH + 17 H+ + 9 malonyl-CoA + acetyl-CoA → 10 coenzyme A + 17 NADP+ + 8 H2O + 9 CO2 + (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate
1,1-ethanediol → H2O + acetaldehyde
(6R)-4a-hydroxy-tetrahydrobiopterin → H2O + quinonoid dihydrobiopterin
NADH + H+ + dimethyl sulfide + oxygen → H2O + formaldehyde + methanethiol + NAD+
4,6-dihydroxy-2-(hydroxymethyl)-3,5-dimethylbenzoate + H+ → H2O + 5,7-dihydroxy-4,6-dimethylphthalide
NADH + 2,6-dihydroxypyridine + H+ + oxygen → H2O + 2,3,6-trihydroxypyridine + NAD+
NADPH + 2,3,5,6-tetracholorophenol + oxygen → H2O + 2,3,5,6-tetrachlorohydroquinone + NADP+
2 a reduced electron donor + JI-20B → 2 an oxidized electron donor + 2 H2O + gentamicin C2
3 ATP + anthranilate + L-tryptophan + L-alanine → 2 H+ + 3 diphosphate + 3 AMP + H2O + ardeemin FQ
palustradiene-diol → H2O + palustradienal
cholesterol + NADPH + H+ + oxygen → H2O + (24S)-24-hydroxycholesterol + NADP+
8,8-dihydroxy-trans-neoxanthin → H2O + fucoxanthinol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-stearoyl-2-palmitoyl-glycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-oleoyl-2-palmitoyl-glycerol
oxygen + tetracenomycin F1 → H2O + H+ + tetracenomycin D3
NADPH + H+ + dimethyl sulfide + oxygen → H2O + dimethyl sulfoxide + NADP+
2-oxoglutarate + H+ + chloride + oxygen + ambiguine I → H2O + succinate + ambiguine E + CO2
2 oxygen + 4 a reduced ferredoxin [iron-sulfur] cluster + 4 H+ + demethylspheroidene → 3 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + demethylspheroidenone
3 H+ + 3 malonyl-CoA + acetyl-CoA + 1,4,5-trihydroxy-Δ2,3-protoilludene → 3 CO2 + 4 coenzyme A + H2O + melleolide F
NADPH + H+ + UDP-α-D-glucose → H2O + NADP+ + UDP-β-L-rhamnose
H2O + NADP+ + D-lysopine ← NADPH + pyruvate + H+ + L-lysine
3 H2O + 3 NADP+ + hydrogen sulfide ← 3 NADPH + 5 H+ + sulfite
a reduced electron donor + 3-[(1E,4R)-4-hydroxycyclohex-2-en-1-ylidene]-2-oxopropanoate + oxygen → an oxidized electron donor + H2O + 3-[(2E,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]-2-oxopropanoate
2 hydrogen peroxide + 2 chloride + H+ + sulochrin → 4 H2O + dihydrogeodin
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + cholesterol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + (25R)-26-hydroxycholesterol + H2O
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + spirilloxanthin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2-hydroxyspirilloxanthin + H2O
H+ + 6α-hydroxy-germacra-1(10),4,11(13)-trien-12-oate → H2O + (+)-costunolide (12,6α)
H+ + betalamate + leucodopachrome → H2O + betanidin
a reduced electron donor + deoxycohumulone + oxygen → an oxidized electron donor + H2O + cohumulone
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + pikromycin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + novapikromycin
2 glutathione + hydrogen peroxide → 2 H2O + glutathione disulfide
3,5-di-C-glucosyl-2,4,4',6-tetrahydroxydibenzoylmethane → H2O + vicenin-2
(R)-3-(indol-3-yl)lactoyl-CoA → 3-(indol-3-yl)acryloyl-CoA + H2O
2 H+ + 6-hydroxynicotinate + NADH + oxygen → H2O + 2,5-dihydroxypyridine + NAD+ + CO2
2 4-hydroxycoumarin + formaldehyde → dicoumarol + H2O
neoabietadiene-diol → H2O + neoabietadienal
4-(2'-carboxyphenyl)-4-oxobutyryl-CoA + H+ → H2O + 1,4-dihydroxy-2-naphthoyl-CoA
2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate → 2 H2O + 3-amino-4-hydroxybenzoate + H+ + phosphate
NADH + 3-oxo-24-ethyl-cholest-4-ene + H+ + oxygen → H2O + NAD+ + 3-oxo-24-ethyl-26-hydroxy-cholest-4-ene
2 H+ + NADH + 5-methylsalicylate + oxygen → H2O + 4-methylcatechol + NAD+ + CO2
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + candicinolide + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 18-hydroxy candicinolide
H2O + NAD(P)+ + nitrite ← NAD(P)H + H+ + nitrate
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 18-hydroxy candicinolide + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 18-oxo candicinolide
dihydroxydeoxyflexixanthin → H2O + deoxyflexixanthin
NADPH + 20-deoxo-20-dihydro-12,13-deepoxyrosamicin + H+ + oxygen → H2O + 20-deoxo-20-dihydrorosamicin + NADP+
glutathione + 1-aci-nitro-2-phenylethane → H2O + (Z)-1-(glutathion-S-yl)-N-hydroxy-2-phenylethan-1-imine
2 a reduced electron donor + 2 oxygen + myxocoxanthin → 2 an oxidized electron donor + 3 H2O + deoxyflexixanthin
NADPH + (E)-7-(methyltsulfanyl)heptanal oxime + H+ + L-cysteine + oxygen → 2 H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)heptan-1-imine + NADP+
11 H+ + 5 NADPH + 5 (S)-methylmalonyl-CoA + malonyl-CoA → 2 H2O + 5 NADP+ + 6 coenzyme A + 6 CO2 + 10-deoxymethynolide
NADPH + H+ + oxygen + (-)-isodihydrocarvone → H2O + NADP+ + (4S,7R)-4-isopropenyl-7-methyloxepan-2-one
H2O + NADP+ + (+)-afzelechin ← NADPH + H+ + (2R,3S,4S)-leucopelargonidin
levopiramadiene-diol → H2O + levopimaradienal
7,8-dihydro-neoxanthin + a reduced electron donor + oxygen → an oxidized electron donor + 8-hydroxy-trans-neoxanthin + H2O
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-16:1-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:2-2-16:2-monogalactosyldiacylglycerol
kauralexin B1 + oxygen → H2O + kauralexin B3
2-(phosphonoylmethyl)malate → H2O + 2-(phosphinatomethylidene)butanedioate
ammonia + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine + H+ → H2O + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 flaviolin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 3,3'-biflaviolin
11 NADPH + 2 (S)-methylmalonyl-CoA + 22 H+ + 9 malonyl-CoA → 11 coenzyme A + 11 NADP+ + 11 CO2 + 5 H2O + spinosyn macrolactone
NADPH + stipitaldehydate + H+ + oxygen → 2 H2O + stipitatonate + NADP+
androsta-1,4-diene-3,17-dione + NADH + H+ + oxygen → 9α-hydroxyandrosta-1,4-diene-3,17-dione + H2O + NAD+
a reduced electron donor + oxygen + ε-carotene → an oxidized electron donor + 3-hydroxy-ε,ε-carotene + H2O
NADPH + H+ + methyl (2E,6E)-farnesoate + oxygen → H2O + juvenile hormone III + NADP+
farnesyl-5,7-dihydroxy-4,6-dimethylphthalide + a reduced electron donor + oxygen → an oxidized electron donor + H2O + epoxyfarnesyl-5,7-dihydroxy-4,6-dimethylphthalide
2 oxygen + β-fenchene → H2O + β-fenchocamphorone + CO2
dihydrochanoclavine-I aldehyde → H2O + 6,8-dimethyl-6,7-didehydroergoline
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + pheophorbide a → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + epoxypheophorbide a
ammonia + a reduced electron donor + oxygen → an oxidized electron donor + H2O + hydroxylamine
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate → H2O + (S)-2,3-dihydrodipicolinate
H2O + 3-hydroxyquinaldate + NADP+ ← NADPH + 3-hydroxykynurenate + H+
a reduced electron donor + linoleate + oxygen → 2 H2O + an oxidized electron donor + γ-linolenate
NADPH + trans-cinnamate + H+ + oxygen → H2O + 2-coumarate + NADP+
5S hydro(peroxy),18R-hydroxy-icosapentaenoate + a reduced electron donor → an oxidized electron donor + H2O + resolvin E2
NADPH + oxygen + trimethylamine → H2O + NADP+ + trimethylamine N-oxide
a reduced electron donor + H+ + 4-hydroxylamino-2,6-dinitrotoluene → an oxidized electron donor + H2O + 4-amino-2,6-dinitrotoluene
L-ascorbate + H+ + oxygen + portulacaxanthin II → H2O + L-dehydro-ascorbate + dopaxanthin
17S-hydroperoxydocosahexaenoate + a reduced electron donor + oxygen → an oxidized electron donor + 7S-hydroperoxy,17S-hydroxy-docosahexaenoate + H2O
2 H+ + 3 NADPH + 3 oxygen + 4α,14α-dimethyl-5α-cholesta-8,24-dien-3β-ol → 3 NADP+ + 4 H2O + 4α-methyl-5α-cholesta-8,14,24-trien-3β-ol + formate
(31R)-8-ethyl-71,71-dihydroxy-12-methylbacteriochlorophyllide c → H2O + (31R)-8-ethyl-12-methylbacteriochlorophyllide e
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + adonirubin → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + (3S,3'S)-astaxanthin
FMNH2 + dibenzothiophene-5-oxide + oxygen → FMN + H2O + dibenzothiophene-5,5-dioxide + H+
4 Fe2+ + 4 H+ + oxygen → 2 H2O + 4 Fe3+
(S)-2-hydroxymethylglutarate → H2O + 2-methyleneglutarate
2-oxoglutarate + oxygen + gibberellin A8 → H2O + H+ + succinate + gibberellin A8-catabolite + CO2
monacolin L acid + H+ → H2O + monacolin L lactone
spirilloxanthin + oxygen → H2O + 2-oxospirilloxanthin
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + (4S)-limonene + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + (4S)-perillyl alcohol
4 Mn2+ + 4 H+ + oxygen → 2 H2O + 4 Mn+3
methoxyneurosporene + a reduced electron donor + oxygen → 2 H2O + an oxidized electron donor + spheroidene
2-(2,4-dihydroxy-6-methylbenzoyl)benzene-1,3,5-triol → H2O + norlichexanthone
2 oxygen + 4 a reduced ferredoxin [iron-sulfur] cluster + 4 H+ + spirilloxanthin → 3 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + 2-oxospirilloxanthin
25-hydroxycholesterol + NADPH + H+ + oxygen → H2O + 7α,25-dihydroxycholesterol + NADP+
abietatriene + NADPH + H+ + oxygen → ferruginol + H2O + NADP+
zeinoxanthin + NADPH + H+ + oxygen → lutein + H2O + NADP+
NADPH + H+ + arachidonate + oxygen → H2O + (15R)-hydroxyicosapentaenoate + NADP+
5-hydroxy-2-oxopentanoate → H2O + 2-oxopent-4-enoate
a reduced electron donor + phytosphingosine + oxygen → 2 H2O + an oxidized electron donor + 4-hydroxy-trans-8-sphingenine
4-sulfanylbutanoate + oxygen → H2O + 4-oxo-4-sulfanylbutanoate
13(S)-HPOTE → (11Z)-etherolenate + H2O
4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate → xanthurenate + H2O + H+
(2S)-naringenin + 2-oxoglutarate + oxygen → H2O + H+ + succinate + CO2 + apigenin
NADH + (Z)-3-ureidoacrylate peracid → H2O + NAD+ + 3-ureidoacrylate
1-phenyl-3-(3-C-glucosyl-2,4,6-trihydroxyphenyl)propane-1,3-dione → H2O + 8-C-glucosyl chrysin
2 NADPH + 2 oxygen + (+)-dihydrokaempferol + H+ → 2 H2O + 2 NADP+ + (+)-dihydromyricetin
1-18:2-2-16:0-digalactosyldiacylglycerol + a reduced electron donor + oxygen → 2 H2O + an oxidized electron donor + 1-18:3-2-16:0-digalactosyldiacylglycerol
5-amino-5-deoxy-3-dehydroshikimate → H2O + H+ + 3-amino-5-hydroxybenzoate
H+ + oxygen + violaceinate → H2O + violacein + CO2
2 a reduced ferredoxin [iron-sulfur] cluster + 2 2,4-dibromophenol + H+ + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 3,3',5,5'-tetrabromo-2,2'-biphenyldiol
L-lysine + oxygen → H2O + 5-aminopentanamide + CO2
glutathione + indole-3-carbinol → H2O + indol-3-ylmethyl-glutathione
17-α-hydroxyprogesterone + NADPH + H+ + oxygen → H2O + NADP+ + 11-desoxycortisol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + cholesterol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + (25S)-26-hydroxycholesterol + H2O
2 3-amino-4-hydroxybenzoate + 2 oxygen + N-acetyl-L-cysteine + H+ → 4 H2O + grixazone B + CO2
cyclopentanone + NADPH + H+ + oxygen → H2O + 5-valerolactone + NADP+
NAD(P)H + aurachin B + H+ + oxygen → H2O + NAD(P)+ + aurachin B epoxide
6 H+ + 7 malonyl-CoA → 7 coenzyme A + 7 CO2 + H2O + heptaketide pyrone
2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + nitrite ← 2 a reduced ferredoxin [iron-sulfur] cluster + nitrate
2 D-glyceraldehyde 3-phosphate → 2 H2O + (5-formylfuran-3-yl)methyl phosphate + phosphate
NADPH + H+ + oxygen + (indol-3-yl)pyruvate → H2O + NADP+ + (indol-3-yl)acetate + CO2
(3R,7Z,10Z,13Z,16Z)-3-hydroxydocosatetraenoyl-CoA → H2O + (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA
a reduced electron donor + oxygen + (indol-3-yl)acetaldehyde → an oxidized electron donor + H2O + indole-3-glycol aldehyde
2-oxoglutarate + oxygen + gibberellin A15 (open lactone form) → H2O + succinate + gibberellin A24 + CO2
NADPH + H+ + mycinamicin IV + oxygen → H2O + NADP+ + mycinamicin I
2 hydroxyl radical + CTP → 5-hydroxy-CTP + H2O
a reduced electron donor + 2-[hydroperoxy-(4-glucosyl-hydroxyphenyl)methyl]-6-hydroxy-1-benzofuran-3-one → an oxidized electron donor + H2O + 2-(6-oxo-1-oxaspiro[2.5]octa-4-glucosyl)-6-hydroxy-1-benzofuran-3-one
D-altronate → H2O + 2-dehydro-3-deoxy-D-gluconate
NADPH + H+ + oxygen + prefusarin → H2O + NADP+ + 20-hydroxy-prefusarin
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + (25R)-26-hydroxycholest-4-en-3-one + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + (25R)-26-oxocholest-4-en-3-one
NAD(P)H + 4-methyl-proline + H+ + oxygen → H2O + NAD(P)+ + 3-hydroxy-4-methyl-L-proline
methane + NAD(P)H + H+ + oxygen → H2O + NAD(P)+ + methanol
2-S-cysteinyldopaquinone → 8-[(2S)-2-amino-2-carboxylatoethyl]-5-hydroxy-2H-1,4-benzothiazine-3-carboxylate + H2O + H+
2 9-hydroxyrubrofusarin + NAD(P)H + H+ + oxygen → 2 H2O + NAD(P)+ + dimeric 9-hydroxyrubrofusarin
2-oxoglutarate + oxygen + (2R,3S,4S)-leucodelphinidin → 2 H2O + delphinidin + H+ + succinate + CO2
propene + NADH + H+ + oxygen → H2O + NAD+ + (S)-1,2-epoxypropane
propene + NADH + H+ + oxygen → H2O + NAD+ + (R)-1,2-epoxypropane
1,5-anhydro-D-fructose → H2O + ascopyrone M
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + lanosterol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 30-hydroxylanosterol + H2O
2 H+ + 3 a reduced electron donor + 3 oxygen + protoheme → 3 an oxidized electron donor + 3 H2O + Fe2+ + biliverdin-IX δ + carbon monoxide
anhydrotetracycline + NADPH + H+ + oxygen → H2O + 5a,11a-dehydrotetracycline + NADP+
(2R)-3-[(9S, 9aR)-9-hydroxy-2,2-dimethyl-3-oxo-1H, 2H, 3H, 9H, 9aH-imidazolidino[1,2-a] indol-9-yl]-2-(2-acetyl-4-oxo-3,4-dihydroquinazolin-3-yl) propanoate → H2O + deoxynortryptoquialanone
octopamine → H2O + H+ + 4-[(Z)-2-aminoethenyl]phenol
(13S)-HPODE → (11Z)-etheroleate + H2O
FMNH2 + dibenzothiophene + oxygen → FMN + H2O + H+ + dibenzothiophene-5-oxide
NADPH + 2,3',4,6-tetrahydroxybenzophenone + oxygen → 2 H2O + 1,3,5-trihydroxyxanthone + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + (25R)-26-hydroxycholesterol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + (25R)-26-oxocholesterol
NADH + H+ + 2,2'-dihydroxybiphenyl + oxygen → H2O + 2,2',3-trihydroxybiphenyl + NAD+
H+ + 6α,8β-dihydroxy-germacra-1(10),4,11(13)-trien-12-oate → H2O + eupatolide
α-linolenate + hydrogen peroxide + H+ → 2 H2O + 1E,8Z,11Z,14Z-heptadecatetraene + CO2
a reduced electron donor + oxygen + 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol → an oxidized electron donor + H2O + 3-demethylubiquinol-8
NADH + H+ + oxygen + protoasukamycin → H2O + NAD+ + 4-hydroxyprotoasukamycin
6-oxo-1,8-cineole + NADPH + H+ + oxygen → H2O + 1,6,6-trimethyl-2,7-dioxobicyclo-(3,2,2)nonan-3-one + NADP+
NAD(P)H + phenylacetone + H+ + oxygen → H2O + NAD(P)+ + benzyl acetate
neoabietadiene + NADPH + H+ + oxygen → H2O + NADP+ + neoabietadienol
(2R,3R)-3-methylglutamyl-5-semialdehyde-N6-lysine → H2O + L-pyrrolysine + H+
2 a reduced ferredoxin [iron-sulfur] cluster + H+ + oxygen + pentalen-13-al → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 1-deoxypentalenate
NADH + H+ + 1,3-dimethylbenzene + oxygen → H2O + 3-methylbenzyl alcohol + NAD+
sulfoacetaldehyde + L-cysteine → H2O + 2-(sulfomethyl)thiazolidine-4-carboxylate + H+
2-amino-4-[3-(2-amino-2-carboxylatoethyl)-6-oxocyclohexa-1,4-dien-1-yl]pentanedioate → H2O + 6-(2-amino-2-carboxylatoethyl)-1,2,3,4-tetrahydroquinoline-2,4-dicarboxylate + H+
FADH2 + chloride + oxygen + tetracycline → 2 H2O + FAD + H+ + 7-chlorotetracycline
H+ + anthraniloyl-CoA + 3-oxodecanoate → coenzyme A + H2O + 2-heptyl-4-quinolone + CO2
D-idonate → H2O + 2-dehydro-3-deoxy-D-galactonate
1,2-bis(4-hydroxyphenyl)-2-propanol → H2O + 4,4'-(1E)-prop-1-ene-1,2-diyldiphenol
1-(methylsulfanyl)-7-aci-nitroheptane + glutathione → H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-ω-(methylsulfanyl)heptan-1-imine
hydrogen peroxide + 1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol → H2O + glycolaldehyde + vanillin + guaiacol
(Z)-[(4-hydroxyphenyl)acetaldehyde oxime] → H2O + (4-hydroxyphenyl)acetonitrile
(Z)-phenylacetaldehyde oxime → H2O + phenylacetonitrile
2 NADPH + 3 H+ + oxygen + (4S)-2-acetyl-3,4,8,10,11,12-hexahydroxy-1,4-dihydrotetracen-1-one → 2 NADP+ + H2O + 4-demethylpremithracinone
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + N-methyl-L-valyl-L-tryptophanol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + (-)-indolactam V
1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate + H+ → H2O + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2
D-serine → H2O + H+ + 2-aminoprop-2-enoate
NADPH + H+ + oxygen + (2-ethylpyridin-4-yl)(imino)methanesulfinate → H2O + sulfur dioxide + NADP+ + 2-ethyl-4-amidopyridine
L-ascorbate + H+ + (S)-amphetamine + oxygen → H2O + L-dehydro-ascorbate + (-)-norephedrine
12-deoxyaklanoate + oxygen → aklanonate + H2O
zeaxanthin + NAD(P)H + H+ + oxygen → antheraxanthin + H2O + NAD(P)+
cotinine + NADPH + H+ + oxygen → H2O + 5'-hydroxycotinine + NADP+
4-(2-aminophenyl)-2,4-dioxobutanoate → H2O + kynurenate + H+
L-tyrosine + 3'-amino-3'-deoxyadenosine → H2O + N6,N6,O-tridemethylpuromycin
a reduced electron donor + (8Z,11Z,14Z,17Z)-icosatetraenoyl-CoA + oxygen → 2 H2O + an oxidized electron donor + (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA
2 columbamine + oxygen → 2 H2O + 2 berberine
L-ascorbate + dopamine + H+ + oxygen → H2O + L-dehydro-ascorbate + (R)-noradrenaline
NAD(P)H + H+ + oxygen + asperlicin C → H2O + NAD(P)+ + asperlicin E
7S-hydroperoxy,17S-hydroxy-docosahexaenoate → 7,8-epoxy-17S-hydroxy-docosahexaenoate + H2O
3 H+ + cacodylate → H2O + dimethylarsinous acid
1-deoxy-2,3-hexodiulose-6-phosphate → H2O + phosphate + 4-hydroxy-5-methyl-2-methylene-3(2H)-furanone
salicylate + NADH + H+ + oxygen → H2O + gentisate + NAD+
α-linolenate + a reduced electron donor + oxygen → 2 H2O + an oxidized electron donor + stearidonate
2 (1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylate → 2 H2O + 2 H+ + (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate
2,5-xylenol + NADH + H+ + oxygen → H2O + 5-(hydroxymethyl)-2-methylphenol + NAD+
strictosidine aglycone → H2O + cathenamine
(4S)-2,3-dehydro-leucocyanidin → cyanidin + H2O + H+
L-proline betaine + NAD(P)H + H+ + oxygen → H2O + N-methyl-L-proline + NAD(P)+ + formaldehyde
2 NADPH + 2 bromide + 2 oxygen + 5 H+ + protocatechuate → 2 NADP+ + 4 H2O + 3,5-dibromocatechol + CO2
(+)-dihydromyricetin + 2-oxoglutarate + oxygen → myricetin + H2O + succinate + CO2
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + 3,5-dibromocatechol + 2,4-dibromophenol → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 6,6'-oxybis(2,4-dibromophenol)
NADH + H+ + 3-methylphenol + oxygen → H2O + 3-hydroxybenzyl alcohol + NAD+
NADPH + H+ + oxygen + (+)-α-santalene → H2O + NADP+ + (+)-α-santalol
2 oxygen + 3 H+ + 4 a reduced ferredoxin [iron-sulfur] cluster + nocardicin C → 3 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + nocardicin A
UDP-N-acetyl-α-D-glucosamine → H2O + UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hex-4-ulose
H+ + oxygen + (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate → H2O + paerucumarin
2 H+ + 3 a reduced electron donor + 3 oxygen + protoheme → 3 an oxidized electron donor + 3 H2O + Fe2+ + biliverdin-IX β + carbon monoxide
3 H2O + 6 an oxidized ferredoxin [iron-sulfur] cluster + hydrogen sulfide ← 6 a reduced ferredoxin [iron-sulfur] cluster + 8 H+ + sulfite
(2R,3S)-2,7-dihydroxy-4'-methoxyisoflavanone → H2O + formononetin
L-phenylalanine + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + oxygen → H2O + L-tyrosine + (6R)-6,7-dihydrobiopterin
NADH + H+ + fluorene + oxygen → H2O + NAD+ + 9-fluorenol
(3R,6E)-nerolidol + NADPH + H+ + oxygen → 2 H2O + but-3-en-2-one + NADP+ + (3E)-4,8-dimethylnona-1,3,7-triene
3-[(2-aminophenyl)amino]-2-oxopropanoate → H2O + 3,4-dihydroquinoxaline-2-carboxylate
3-C-glucosyl-2,4,4',6-tetrahydroxydibenzoylmethane → H2O + vitexin
secologanin + dopamine → H2O + deacetylisoipecoside
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + cholest-4-en-3-one + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + (25S)-26-hydroxycholest-4-en-3-one
pregnenolone + NADH + oxygen → H2O + (20S)-17,20-dihydroxypregn-4-en-3-one + NAD+
2 H+ + protocatechuate + NADPH + bromide + oxygen → 2 H2O + NADP+ + 3-bromo-4,5-dihydroxybenzoate
2 L-ascorbate + 2 H+ + hydrogen peroxide → 2 H2O + 2 monodehydroascorbate radical
β-D-fructofuranose 6-phosphate + phosphate → D-erythrose 4-phosphate + acetyl phosphate + H2O
NADPH + H+ + 2-chlorophenol + oxygen → H2O + NADP+ + 3-chlorocatechol
1,3,5-trihydroxyxanthone + NADPH + H+ + oxygen → H2O + 1,3,5,8-tetrahydroxyxanthone + NADP+
2-methylprop-1-ene + NADH + H+ + oxygen → H2O + 1,2-epoxy-2-methylpropane + NAD+
NAD(P)H + prejadomycin + H+ + oxygen → 2 H2O + NAD(P)+ + 8-methyltetraphene-1,5,6,11,12-pentol
2 H+ + NADH + 5-chlorosalicylate + oxygen → H2O + NAD+ + 4-chlorocatechol + CO2
NADPH + aurachin D + H+ + oxygen → H2O + 9'-hydroxy-aurachin D + NADP+
(+)-taxifolin + NADPH + H+ + oxygen → H2O + (+)-dihydromyricetin + NADP+
hydrogen peroxide + methanol → 2 H2O + formaldehyde
chanoclavine-I aldehyde → H2O + 6,8-dimethyl-6,7,8,9-tetradehydroergoline
NADH + methyl tert-butyl ether + H+ + oxygen → H2O + tert-butoxymethanol + NAD+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-oleoyl-2-palmitoyl-phosphatidylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-oleoyl-2-(3E)-hexadecenoyl-phosphatidylglycerol
3-hydroxy-2-oxopropyl 7-methyl-3-oxooctanoate → H2O + 4-(hydroxymethyl)-3-(5-methylhexanoyl)-5H-furan-2-one
2 H+ + an oxidized electron donor + hydrodidemethylasterriquinone D + prenyl diphosphate → ochrindole D + H2O + a reduced electron donor + diphosphate
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 4-nitrotoluene + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 4-nitrobenzyl alcohol
(9S)-HPODE → H2O + 9,10-epoxy-10,12Z-octadecadienoate
NADPH + H+ + oxygen + tetracycline → H2O + NADP+ + 11a-hydroxytetracycline
renierapurpurin + a reduced electron donor + oxygen → an oxidized electron donor + 18-hydroxyrenierapurpurin + H2O
a reduced electron donor + urolithin C → an oxidized electron donor + H2O + isourolithin A
abieta-7,13-dien-18,18-diol → H2O + abieta-7,13-diene-18-al
FADH2 + 4-coumarate + oxygen → FAD + H2O + H+ + trans-caffeate
2 NADPH + 2 H+ + 17-α-hydroxypregnenolone + oxygen → 2 H2O + 2 NADP+ + acetaldehyde + 3-β-hydroxyandrost-5-en-17-one
2 NAD(P)H + 2 H+ + 2 oxygen + zeaxanthin → 2 H2O + 2 NAD(P)+ + violaxanthin
2 NADPH + 2 H+ + 7,2'-dihydroxy-4',5'-methylenedioxyisoflavan + oxygen → 2 NADP+ + H2O + 10,2'-dihydroxy-4',5'-methylenedioxy-isoflav-8-ene-7-one
Coα-[α-(5-hydroxybenzimidazolyl)]-cobamide + methanol + H+ → H2O + Coα-[α-(5-hydroxybenzimidazolyl)]-Coβ-methylcobamide
hercynine + L-cysteine + oxygen → H2O + S-(hercyn-2-yl)-L-cysteine S-oxide
NAD(P)H + 1-methylxanthine + H+ + oxygen → xanthine + H2O + NAD(P)+ + formaldehyde
FMNH2 + methanesulfinate + oxygen → FMN + H2O + methanesulfonate + H+
2-oxoglutarate + H+ + chloride + oxygen + 12-epi-fischerindole U → H2O + succinate + CO2 + 12-epi-fischerindole G
2-hydroxypyridine + a reduced electron donor + oxygen → an oxidized electron donor + H2O + 2,5-dihydroxypyridine
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + neopikromycin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + novapikromycin
hydrogen peroxide + L-methionine → H2O + L-methionine-(S)-S-oxide
fusicocca-2,10(14)-diene-8β,16-diol + 2-oxoglutarate + oxygen → 8β-hydroxyfusicocca-1,10(14)-diene-16-al + H2O + succinate + CO2
NADPH + H+ + 2-octaprenylphenol + oxygen → H2O + NADP+ + 3-(all-trans-octaprenyl)benzene-1,2-diol
NAD(P)H + H+ + 3-chloro-4-(3-chloro-2-nitrosophenyl)-1H-pyrrole + oxygen → H2O + pyrrolnitrin + NAD(P)+
H+ + ammonium hydroxide → H2O + ammonium
FMNH2 + 5-hydroxyadamantan-2-one + oxygen → FMN + H2O + 1-hydroxy-4-oxahomoadamantan-5-one + H+
2 NADPH + 2 oxygen + benzaldehyde + H+ → 2 NADP+ + H2O + 6-hydroxy-2-cyclohexen-one-carboxylate
a reduced electron donor + oxygen + β-carotene → an oxidized electron donor + β-carotene 15,15' epoxide + H2O
trans-neoxanthin → diadinoxanthin + H2O
triethylamine + NADPH + H+ + oxygen → H2O + NADP+ + triethylamine N-oxide
2 H+ + NADH + 5-methylphenazine-1-carboxylate + oxygen → H2O + NAD+ + pyocyanin + CO2
NADPH + 5-methyl-N-(4-nitrophenyl)thiophene-2-carboxamide + H+ + oxygen → H2O + 5-methyl-N-(4-nitrophenyl)-1-oxo-1λ4-thiophene-2-carboxamide + NADP+
2 hydroxyl radical + GTP → H2O + 8-oxo-GTP
3 2-oxoglutarate + 3 H+ + 3 oxygen + L-arginine → 2 ethene + 3 H2O + 7 CO2 + guanidinium + (S)-1-pyrroline-5-carboxylate + succinate
dehydroprephenate + H+ → H2O + 3-(cyclohexa-1,3-dien-1-yl)-2-oxopropanoate + CO2
2 H+ + 3 NADPH + 3 oxygen + decarboxy-demycosaminyl-nystatin → 3 NADP+ + 4 H2O + demycosaminyl-nystatin
3 2,3-dihydroxybenzoate + 3 glycine + 3 L-threonine + 6 ATP → 3 H2O + 3 H+ + 6 diphosphate + 6 AMP + bacillibactin
2 2,4-dibromophenol + 3 H+ + 4 a reduced ferredoxin [iron-sulfur] cluster + oxygen → 2 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + 2-bromo-4-(2,4-dibromophenoxy)phenol + bromide
2-oxoglutarate + andilesin C + oxygen → H2O + succinate + anditomin + CO2
trans-3-hydroxy-L-proline → H2O + 1-pyrroline-2-carboxylate + H+
3 oxygen + 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline 2,4-dicarboxylate → 2 H2O + 2 hydrogen peroxide + pyrroloquinoline quinone + H+
(1S,4R)-1-hydroxymenth-8-en-2-one + NADPH + H+ + oxygen → (4R)-7-hydroxy-4-isoprenyl-7-methyl-2-oxo-oxepanone + H2O + NADP+
L-threonine → H2O + H+ + (2Z)-2-aminobut-2-enoate
(3S,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol → H2O + (+)-medicarpin
hydrogen peroxide + trypanothione → 2 H2O + trypanothione disulfide
5-deoxy-dihydrokalafungin + oxygen → H2O + dihydrokalafungin
a reduced electron donor + oxygen + 6-methoxy-3-methyl-2-all-trans-heptaprenyl-1,4-benzoquinol → an oxidized electron donor + H2O + 3-demethylubiquinol-7
NADPH + H+ + 2-heptaprenylphenol + oxygen → H2O + NADP+ + 3-(all-trans-heptaprenyl)benzene-1,2-diol
NADPH + H+ + oxygen + premithramycin B → H2O + NADP+ + premithramycin B lactone
2 cis-caffeate + oxygen → 2 (2Z)-3-(3,4-dioxocyclohexa-1,5-dien-1-yl)prop-2-enoate + 2 H2O
2-oxoglutarate + oxygen + cyclopeptine → H2O + succinate + CO2 + dehydrocyclopeptine
6-hydroxy-2-[(4-glucosyl-hydroxyphenyl)methyl]-1-benzofuran-3-one → H2O + hispidol-4'-O-β-D-glucoside
NADPH + H+ + 3-heptaprenyl-4-hydroxybenzoate + oxygen → 3,4-dihydroxy-5-all-trans-heptaprenylbenzoate + H2O + NADP+
dimethyl sulfoxide + NAD(P)H + H+ → H2O + NAD(P)+ + dimethyl sulfide
3α-hydroxy-3,5-dihydromonacolin L acid → H2O + monacolin L acid
a reduced electron donor + oxygen + 6-methoxy-3-methyl-2-all-trans-nonaprenyl-1,4-benzoquinol → an oxidized electron donor + H2O + 3-demethylubiquinol-9
2 glutathione amide + hydrogen peroxide → 2 H2O + glutathione amide disulfide
N-acetylindoxyl + oxygen → H2O + N-acetylisatin
dihydroclavaminate + 2-oxoglutarate + oxygen → H2O + succinate + clavaminate + CO2
H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-α-D-glucose ← NAD(P)H + H+ + CDP-4-dehydro-6-deoxy-α-D-glucose
NADH + H+ + dibenzothiophene + oxygen → H2O + NAD+ + dibenzothiophene-5-oxide
3 H+ + 3 malonyl-CoA + NADPH + S-adenosyl-L-methionine + acetyl-CoA → 3 CO2 + 4 coenzyme A + H2O + S-adenosyl-L-homocysteine + 3-methylorcinaldehyde + NADP+
3-hydroxy-ε,ε-carotene + a reduced electron donor + oxygen → an oxidized electron donor + lactucaxanthin + H2O
2 H+ + NAD(P)H + 4-hydroxybenzoate + oxygen → H2O + NAD(P)+ + hydroquinone + CO2
1-(methylsulfanyl)-6-aci-nitrohexane + glutathione → H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-ω-(methylsulfanyl)hexan-1-imine
hydroxydeoxyflexixanthin + a reduced electron donor + oxygen → an oxidized electron donor + dihydroxydeoxyflexixanthin + H2O
NADPH + 7-(methylsulfanyl)heptyl-glucosinolate + H+ + oxygen → H2O + NADP+ + 7-(methylsulfinyl)heptyl-glucosinolate
2 a reduced ferredoxin [iron-sulfur] cluster + 30-oxolanosterol + H+ + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 4,4-dimethyl-5-α-cholesta-8,14,24-trien-3-β-ol + H2O + formate
ammonium + UDP-2,3-diacetamido-2,3-dideoxy-α-D-mannuronate → H2O + UDP-2-acetamido-3-acetamidino-2,3-dideoxy-α-D-mannuronate
6-deoxyerythronolide B + NADPH + H+ + oxygen → H2O + NADP+ + erythronolide B
NADPH + H+ + oxygen + (S)-autumnaline → 2 H2O + NADP+ + (S)-isoandrocymbine
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 3-oxo-23,24-bisnorchol-1,4-dien-22-yl-CoA + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 9α-hydroxy-3-oxo-23,24-bisnorchol-1,4-dien-22-yl-CoA
3 H+ + 3 malonyl-CoA + NADPH + acetyl-CoA → 3 CO2 + 4 coenzyme A + H2O + 6-methylsalicylate + NADP+
NADH + theophylline + H+ + oxygen → H2O + 3-methylxanthine + formaldehyde + NAD+
2 NADPH + 3 H+ + (10E,12Z)-10,12-hexadecadienoate → 2 NADP+ + H2O + bombykol
4-fluorophenol + NADH + H+ + oxygen → 4-fluorocatechol + H2O + NAD+
4 tellimagrandin II + oxygen → 2 H2O + 2 cornusiin E
erythromycin D + NADPH + H+ + oxygen → H2O + erythromycin C + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + (25S)-26-hydroxycholesterol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + (25S)-26-oxocholesterol
N,N-dihydroxyhexahomomethioniate + H+ → H2O + (E)-9-(methylsulfanyl)nonanal oxime + CO2
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-16:0-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:2-2-16:1-monogalactosyldiacylglycerol
NAD(P)H + 3-methylorcinaldehyde + H+ + oxygen → H2O + NAD(P)+ + (2R,6Z)-2-hydroxy-6-(hydroxymethylidene)-2,5-dimethylcyclohex-4-ene-1,3-dione
a reduced electron donor + linoleoyl-CoA + oxygen → 2 H2O + an oxidized electron donor + γ-linolenoyl-CoA
NADPH + H+ + oxygen + daunorubicin → H2O + NADP+ + doxorubicin
H2O + NAD+ + 1-deoxy-D-xylulose 5-phosphate ← D-ribulose 5-phosphate + NADH + H+
butein 4'-β-D-glucoside + oxygen → H2O + aureusidin 6-O-glucoside
5α-cholesta-7,24-dien-3β-ol + NAD(P)H + H+ + oxygen → 2 H2O + 7-dehydrodesmosterol + NAD(P)+
3,5-xylenol + NADH + H+ + oxygen → H2O + 3-(hydroxymethyl)-5-methylphenol + NAD+
NADPH + H+ + phenylacetyl-CoA + oxygen → H2O + 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + NADP+
cacodylate + a reduced electron donor + H+ → an oxidized electron donor + H2O + dimethylarsinous acid
NADPH + H+ + oxygen + aklavinone → H2O + ε-rhodomycinone + NADP+
a reduced electron donor + oxygen + 5,6-dihydroxyindole → 2 H2O + an oxidized electron donor + indole-5,6-quinone
L-ornithine + NAD(P)H + oxygen → H2O + NAD(P)+ + N5-hydroxy-L-ornithine
oxygen + (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate → H2O + (2E)-3-(3,4-dioxocyclohexa-1,5-dien-1-yl)-2-isocyanoprop-2-enoate
NADPH + H+ + oxygen + 13-dihydrodaunorubicin → 2 H2O + NADP+ + daunorubicin
FADH2 + L-tyrosine + oxygen → FAD + H2O + L-dopa + H+
NADPH + H+ + palmitoyl-CoA + oxygen → H2O + NADP+ + 16-hydroxypalmitoyl-CoA
3 oxygen + 4 H+ + 6 a reduced ferredoxin [iron-sulfur] cluster + cyclo(L-leucyl-L-leucyl) → 4 H2O + 6 an oxidized ferredoxin [iron-sulfur] cluster + pulcherriminic acid
(R)-reticuline + NADPH + H+ + oxygen → 2 H2O + salutaridine + NADP+
a reduced electron donor + urolithin E → an oxidized electron donor + H2O + urolithin M7
a reduced electron donor + urolithin M6 → an oxidized electron donor + H2O + urolithin M7
NADH + methanesulfonate + oxygen → H2O + formaldehyde + NAD+ + sulfite
(-)-yatein + 2-oxoglutarate + oxygen → (-)-deoxypodophyllotoxin + H2O + succinate + CO2
NADPH + H+ + oxygen + 4-aminobenzoate → H2O + 4-hydroxylaminobenzoate + NADP+
a reduced electron donor + oxygen + 6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol → an oxidized electron donor + H2O + 3-demethylubiquinol-10
2 H+ + 4-nitrophenol + NADH + oxygen → H2O + 4-nitrocatechol + NAD+
a reduced electron donor + 2-oxoglutarate + preandiloid C + oxygen → an oxidized electron donor + H2O + succinate + andiconin + CO2
dihomocitrate → H2O + cis-(homo)2aconitate
NADPH + H+ + 2-chloro-4-methylphenol + oxygen → H2O + NADP+ + 3-chloro-5-methylcatechol
NADPH + H+ + oxygen + 2-cis-abscisate → H2O + NADP+ + 8'-hydroxyabscisate
NADPH + resorcinol + H+ + oxygen → H2O + NADP+ + hydroxyquinol
(31R)-8,12-diethyl-71,71-dihydroxybacteriochlorophyllide c → H2O + (31R)-8,12-diethylbacteriochlorophyllide e
3 NADPH + 3 H+ + 3 oxygen + ethionamide → 3 H2O + 3 NADP+ + sulfur dioxide + 2-ethyl-4-amidopyridine
molybdopterin adenine dinucleotide + H+ + molybdate → H2O + MoO2-molybdopterin cofactor + AMP
(9S)-HPODE → colneleate + H2O
a reduced electron donor + oxygen + γ-coniceine → an oxidized electron donor + H2O + H+ + 5-hydroxy-γ-coniceine
2 rubrofusarin + NAD(P)H + H+ + oxygen → 2 H2O + NAD(P)+ + dimeric rubrofusarin
3 N-hydroxy-N-succinylcadaverine + ATP → H2O + desferrioxamine G1 + H+ + diphosphate + AMP
17S-hydroperoxydocosahexaenoate + NADPH + H+ → 17S-hydroxydocosahexaenoate + H2O + NADP+
5 H+ + MoO2-molybdopterin cofactor + GTP → 2 H2O + guanylyl molybdenum cofactor + diphosphate
NADH + H+ + flaviolin + oxygen → H2O + NAD+ + mompain
FMNH2 + (+)-bornane-2,5-dione + oxygen → FMN + H2O + (+)-5-oxo-1,2-campholide + H+
preuroporphyrinogen → H2O + uroporphyrinogen-III
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:3-2-18:2-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-18:3-monogalactosyldiacylglycerol
4 a reduced ferredoxin [iron-sulfur] cluster + 5 H+ + 2-hexaprenyl-3-methyl-6-methoxyaminophenol + oxygen → 4 an oxidized ferredoxin [iron-sulfur] cluster + H2O + ammonium + 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol
NADH + H+ + toluene + oxygen → H2O + NAD+ + 2-methylphenol
NADPH + H+ + oxygen + 3,6,7,4'-tetramethylquercetagetin → H2O + NADP+ + 2'-hydroxy 3,6,7,4'-tetramethylquercetagetin
L-dopa + betalamate → H2O + H+ + dopaxanthin
trichloroethanol + oxygen → H2O + 2,2,2-trichloroacetate + H+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + vitamin D3 + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + calcidiol
(13S)-HPODE → etheroleate + H2O
hydrogen peroxide + arachidate + H+ → 2 H2O + 1-nonadecene + CO2
2 H+ + (+)-taxifolin + NAD(P)H + oxygen → H2O + NAD(P)+ + 2,3-dihydrogossypetin
2-oxoglutarate + H+ + oxygen + (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate → 2 CO2 + H2O + succinate + 4-[(E)-2-isocyanoethenyl]phenol
NADPH + H+ + oxygen + 71-hydroxychlorophyllide a → H2O + NADP+ + 71-dihydroxychlorophyllide a
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + p-cymene + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 4-isopropylbenzyl alcohol
NADPH + H+ + oxygen + tetracenomycin A2 → H2O + NADP+ + 4-hydroxytetracenomycin A2
2-oxoglutarate + oxygen + (2R,3S,4S)-leucocyanidin → H2O + (4S)-2,3-dehydro-leucocyanidin + succinate + CO2
an oxidized electron donor + H2O + ammonium ← hydroxylamine + a reduced electron donor + H+
NAD+ + 2-ethyl-4-amidopyridine → H2O + ETH-NAD-imine adduct
2 H+ + NAD(P)H + oxygen + fumiquinazoline F → H2O + NAD(P)+ + fumiquinazoline F-indoline-3'-ol
L-ornithine + oxygen → H2O + L-5-hydroxyornithine
NADPH + H+ + leukotriene B4 + oxygen → H2O + NADP+ + 20-hydroxy-leukotriene B4
(24R)-cholest-5-ene-3β,24-diol + NADPH + H+ + oxygen → H2O + (24R)-cholest-5-ene-3β,7α,24-triol + NADP+
hydroxyferroheme i → H2O + ferroheme a
glycine + NAD+ + hydrogen sulfide → 2 H+ + 3 H2O + nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate
2 H+ + 2-heptaprenylphenol + oxygen → H2O + 3-(all-trans-heptaprenyl)benzene-1,2-diol
NAD(P)H + H+ + 4-hydroxybenzoate + oxygen → protocatechuate + H2O + NAD(P)+
NADPH + H+ + oxygen + geraniol → H2O + NADP+ + 9-hydroxygeraniol
2 2,4-dibromophenol + 3 H+ + 4 a reduced ferredoxin [iron-sulfur] cluster + oxygen → 2 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + bromide + 4',4,6-tribromo-2,2-biphenol
NADPH + oxygen + pentalen-13-al → H2O + NADP+ + 1-deoxypentalenate
4'-hydroxy-4,4'-diapolycopen-4-al + a reduced electron donor + oxygen → an oxidized electron donor + 4',4'-dihydroxy-4,4'-diapolycopen-4-al + H2O
5-amino-2-oxopentanoate → H2O + 1-pyrroline-2-carboxylate + H+
2-hydroxybiphenyl + NADH + H+ + oxygen → H2O + biphenyl-2,3-diol + NAD+
6-hydroxyprotopine → 2 H2O + dihydrosanguinarine
2 2-imino-3-(indol-3-yl)propanoate + hydrogen peroxide → 2 H2O + N-[2-(carboxylatoamino)-1,2-bis(1H-indol-3-yl)ethyl]carbamate
NADPH + oxygen + tetracycline → 2 H2O + 2 carbon monoxide + NADP+ + 3-[(2Z,4Z)-5-carbamoyl-3-(dimethylamino)-4-hydroxypenta-2,4-dien-1-yl]-1,8-dihydroxy-4-methylnaphthalene-2-carboxylate
2-dehydro-3-deoxy-D-arabinonate → H2O + 2,5-dioxopentanoate
anthranilate + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + oxygen → H2O + L-erythro-7,8-dihydrobiopterin + 3-hydroxyanthranilate
N-(1-phenylpropan-2-yl)hydroxylamine + NADPH + H+ + oxygen → 2 H2O + (E)-N-(1-phenylpropan-2-ylidene)hydroxylamine + NADP+
4,4-dihydroxyzeaxanthin → H2O + adonixanthin
FMN + oxygen → H2O + 8-demethyl-8-formylriboflavin 5'-phosphate
3 S-adenosyl-L-methionine + 3 L-cysteine + 8 H+ + NADPH + (salicyl)adenylate + malonyl-CoA → 3 S-adenosyl-L-homocysteine + 8 H2O + coenzyme A + NADP+ + yersiniabactin + AMP
3 oxygen + 5 H+ + 6 a reduced ferredoxin [iron-sulfur] cluster + cholesterol → 4 H2O + 6 an oxidized ferredoxin [iron-sulfur] cluster + (25S)-3β-hydroxycholest-5-en-26-oate
NAD(P)H + H+ + oxygen + protodeoxyviolaceinate → H2O + NAD(P)+ + protoviolaceinate
6-hydroxy-2-[hydroxy-(4-hydroxyphenyl)methyl]-1-benzofuran-3-one → H2O + hispidol
zeaxanthin + NADPH + oxygen → antheraxanthin + H2O + NADP+
progesterone + NADPH + H+ + oxygen → H2O + 11-deoxycorticosterone + NADP+
H2O + NADP+ + nitrite ← NADPH + H+ + nitrate
5β-cholestane-3α,7α-diol + NADPH + H+ + oxygen → H2O + NADP+ + (25R)-5β-cholestane-3α,7α,26-triol
a reduced electron donor + 4,4'-diaponeurosporen-1-ol + oxygen → an oxidized electron donor + H2O + 4,4'-diaponeurosporen-1,1-diol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-16:1-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-16:1-monogalactosyldiacylglycerol
3 oxygen + 5 H+ + 6 a reduced ferredoxin [iron-sulfur] cluster + cholesterol → 4 H2O + 6 an oxidized ferredoxin [iron-sulfur] cluster + (25R)-3β-hydroxycholest-5-en-26-oate
2 cis-4-hydroxy-D-proline + oxygen → 2 H2O + 2 (3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1,4-dimethylbenzene + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 4-methylbenzyl alcohol
dimethyl sulfoxide + NADH + H+ → H2O + NAD+ + dimethyl sulfide
(R)-3-(4-hydroxyphenyl)lactoyl-CoA → H2O + (E)-4-coumaroyl-CoA
2 H+ + 4 oxygen + 5 a reduced electron donor + protoheme → 4 H2O + 5 an oxidized electron donor + Fe2+ + formaldehyde + δ-staphylobilin
NADPH + H+ + oxygen + elymoclavine → 2 H2O + NADP+ + elymoclavine aldehyde
4-imidazoleacetate + NADH + oxygen → H2O + 5-hydroxy-4-imidazoleacetate + NAD+
(3R,4R)-7,2,4,2'-tetrahydroxy-4',5'-methylenedioxyisoflav-3-ene → H2O + (+)-6a-hydroxymaackiain
2 3,5-dibromocatechol + 3 H+ + 4 a reduced ferredoxin [iron-sulfur] cluster + oxygen → 2 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + 3-bromo-5-(3,5-dibromo-2-hydroxyphenoxy)benzene-1,2-diol + bromide
dopamine + betalamate → H2O + H+ + miraxanthin V
NADPH + (-)-pluviatolide + H+ + oxygen → 2 H2O + hinokinin + NADP+
FADH2 + 2,4,6-trichlorophenol + oxygen → FAD + H2O + 2,6-dichlorohydroquinone + chloride
2-dehydro-3-deoxy-L-arabinonate → H2O + 2,5-dioxopentanoate
11 NADPH + 18 H+ + 8 malonyl-CoA + S-adenosyl-L-methionine + acetyl-CoA → 11 NADP+ + 6 H2O + 8 CO2 + 9 coenzyme A + S-adenosyl-L-homocysteine + dihydromonacolin L lactone
2 hydrogen peroxide + isoliquiritigenin 4'-glucoside → 2 H2O + 2-[hydroperoxy-(4-glucosyl-hydroxyphenyl)methyl]-6-hydroxy-1-benzofuran-3-one
4β-formyl-4α-methyl-5α-cholesta-8-en-3β-ol + NADH + oxygen → H2O + NAD+ + 4β-carboxy-4α-methyl-5α-cholesta-8-en-3β-ol
NADH + H+ + oxygen + echinenone → H2O + NAD+ + 3'-hydroxyechinenone
L-aspartate 4-semialdehyde + pyruvate → H2O + H+ + (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
H+ + oxygen + 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol → H2O + 3-demethylubiquinol-8
2 allylsulfenate → H2O + allicin
an oxidized electron donor + L-phenylalanine + H+ + L-proline + L-alanine + lysergate → 3 H2O + a reduced electron donor + ergotamine
11 NADPH + 11 H+ + 2 malonyl-CoA + 5 (S)-methylmalonyl-CoA + (2S)-ethylmalonyl-CoA → 11 NADP+ + 3 H2O + 8 coenzyme A + 8 CO2 + tylactone
NADH + 4β-hydroxymethyl-4α-methyl-5α-cholest-7-en-3β-ol + H+ + oxygen → 2 H2O + NAD+ + 3β-hydroxy-4α-methyl-5α-cholest-7-ene-4β-carbaldehyde
androst-4-ene-3,17-dione + NADPH + H+ + oxygen → H2O + testololactone + NADP+
2-oxoglutarate + oxygen + 4'-methoxycyclopeptine → H2O + succinate + CO2 + 4'-methoxydehydrocyclopeptine
H+ + 8β-hydroxy-germacra-1(10),4,11(13)-trien-12-oate → H2O + inunolide
NADH + H+ + oxygen + (indol-3-yl)acetate → H2O + NAD+ + (2-hydroxy-1H-indol-3-yl)acetate
(5R)-albaflavenol + NADPH + H+ + oxygen → 2 H2O + NADP+ + albaflavenone
2 a reduced electron donor + 2 oxygen + ferroheme o → 2 an oxidized electron donor + 3 H2O + ferroheme a
mupirocin P → mupirocin C1 + H2O
2 NADPH + 2 oxygen + (2S)-naringenin + H+ → 2 H2O + 2 NADP+ + (2S)-dihydrotricetin
a reduced electron donor + 15-demethoxy-ε-rhodomycinone + H+ + oxygen → an oxidized electron donor + H2O + β-rhodomycinone + CO2
(Z)-2-methylpropanal-oxime → H2O + 2-methylpropanenitrile
2 hydrogen peroxide + 2 H+ + Fe-coproporphyrin III → 2 CO2 + 4 H2O + protoheme
NADPH + H+ + (-)-jasmonate + oxygen → trans-tuberonic acid + H2O + NADP+
2 oxygen + 4 2-aminophenol → 4 H2O + 4 1,2-benzoquinone monoimine
2 hydrogen peroxide + Reactive Blue 5 → 2 H2O + 2 H+ + phthalate + 3-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]benzenesulfonate + 2,2'-disulfonyl azobenzene
2 NAD(P)H + 2 H+ + anthraniloyl-CoA + oxygen → 2 NAD(P)+ + H2O + 2-amino-5-oxocyclohex-1-enecarboxyl-CoA
hydrogen peroxide + H+ + chloride → H2O + hypochlorous acid
4 H+ + 7-oxoheptanoate + sulfide(2-) → H2O + 7-mercaptoheptanoate
2 ammonia + Ni2+ + precorrin-2 → 2 H2O + H+ + Ni-sirohydrochlorin
a reduced electron donor + urolithin M6 → an oxidized electron donor + H2O + urolithin C
FMNH2 + 1-butanesulfonate + oxygen → 2 H+ + FMN + H2O + butan-1-al + sulfite
(R)-2-hydroxy-4-methylpentanoyl-CoA → H2O + 4-methylpent-2-enoyl-CoA
2 NADPH + 3 H+ + (8E,10E)-dodeca-8,10-dienoate → 2 NADP+ + H2O + (8E,10E)-dodeca-8,10-dienol
3 (R)-methylmalonyl-CoA + 6 NADPH + 9 H+ + stearoyl-CoA → 3 coenzyme A + 3 H2O + 3 CO2 + 6 NADP+ + C27-mycolipanoyl-CoA
NADH + H+ + toluene + oxygen → H2O + benzyl alcohol + NAD+
erythromycin B + NADPH + H+ + oxygen → H2O + erythromycin A + NADP+
NADPH + episterol + H+ + oxygen → 2 H2O + ergosta-5,7,24(28)-trien-3β-ol + NADP+
2,2-dihydroxyspheroidene → H2O + spheroiden-2-one
(1S,4R)-1-hydroxymenth-8-en-2-one + NADPH + oxygen → (3R)-3-isopropenyl-6-oxoheptanoate + H2O + NADP+
androst-4-ene-3,17-dione + a reduced electron donor + oxygen → an oxidized electron donor + H2O + testololactone
H+ + oxygen + dihydroartemisinic acid hydroperoxide → H2O + artemisinin
[(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + NADPH + H+ + oxygen → H2O + [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + NADP+
2 H+ + 3 NADPH + 3 oxygen + magnesium-protoporphyrin IX 13-monomethyl ester → 3 NADP+ + 5 H2O + 3,8-divinyl protochlorophyllide a
taxa-4(20),11-dien-5α-ol + NADPH + H+ + oxygen → H2O + taxa-4(20),11-dien-5α,13α-diol + NADP+
holyrine B → H2O + 3'-O-demethyl-4'-N-demethyl-staurosporine
2 3-[(8Z,11E,13Z)-pentadeca-8,11,13-trien-1-yl] )catechol + oxygen → H2O + dimeric urushiol peroxide
3,4-dihydroxyphenylacetaldehyde + dopamine → H2O + (S)-norlaudanosoline
D-gluconate 6-phosphate → H2O + 2-dehydro-3-deoxy-D-gluconate 6-phosphate
all-trans-4,4'-diapolycopene + a reduced electron donor + oxygen → an oxidized electron donor + 4-hydroxy-4,4'-diapolycopene + H2O
a reduced electron donor + 4-methoxybenzoate + oxygen → an oxidized electron donor + H2O + formaldehyde + 4-hydroxybenzoate
H2O + 5,10-methylene-tetrahydromethanopterin ← tetrahydromethanopterin + formaldehyde
NADPH + H+ + L-tryptophan + oxygen → H2O + 9-N-hydroxy-L-tryptophan + NADP+
NADPH + L-2-aminodecanoate + H+ + oxygen → H2O + L-2-amino-8-hydroxydecanoate + NADP+
H2O + pseudopaline + NADP+ ← (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + NADPH + 2-oxoglutarate + H+
4 H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + oxygen → H2O + 2-methoxy-6-all trans-octaprenyl-1,4-benzoquinol
2 H+ + 2 3-[(8Z,11E,13Z)-pentadeca-8,11,13-trien-1-yl] )catechol + oxygen → 2 H2O + 8'-(3,4-dihydroxy-5-alkenyl)phenyl-3-[9'E,11'E,13'Z-pentadecatrienyl]catechol
D-4-hydroxyphenylglycine-L-seryl-L 4-hydroxyphenylglycine → H2O + nocardicin G
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2-hydroxy-5-methyl-1-naphthoate + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2,7-dihydroxy-5-methyl-1-naphthoate + H2O
(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran + tetrahydroxoborate → 2 H2O + (2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran-borate
dTDP-4-dehydro-β-L-rhamnose → H2O + dTDP-3,4-didehydro-2,6-dideoxy-β-L-glucose
ethanedisulfonate + NADH + oxygen → H2O + sulfoacetaldehyde + NAD+ + sulfite
1-keto-D-chiro-inositol → 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione + H2O
(3R)-3-hydroxy-arachidoyl-CoA → H2O + trans-arachido-2-enoyl-CoA
3R-hydroxy-(11Z)-eicos-11-enoyl-CoA → H2O + (2E,11Z)-icosa-2,11-dienoyl-CoA
2 H+ + oxygen + 5,6-dihydroxyindole → 2 H2O + indole-5,6-quinone
3 oxygen + 6-(2-amino-2-carboxylatoethyl)-7-hydroxy-8-oxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate → 2 H2O + 2 hydrogen peroxide + 2 H+ + pyrroloquinoline quinone
propane + NADH + H+ + oxygen → H2O + propan-1-ol + NAD+
deoxynogalonate + oxygen → H2O + nogalonate
4',4'-dihydroxyadonixanthin → H2O + (3S,3'S)-astaxanthin
2 hydrogen peroxide + palmitate + H+ → 3 H2O + pentadecanal + CO2
N,N-dihydroxy-L-tyrosine + H+ → H2O + (E)-(4-hydroxyphenyl)acetaldehyde oxime + CO2
NADPH + putrescine + H+ + oxygen → H2O + 2-hydroxyputrescine + NADP+
hydrogen peroxide + ethanol → 2 H2O + acetaldehyde
NAD(P)H + H+ + oxygen + phenazine-1-carboxylate → H2O + 2-hydroxyphenazine-1-carboxylate + NAD(P)+
NADPH + H+ + (-)-jasmonate + oxygen → trans-11-hydroxyjasmonate + H2O + NADP+
dTDP-α-D-glucose → H2O + dTDP-4-dehydro-6-deoxy-α-D-glucopyranose
chorismate → H2O + 3-[(1-carboxyvinyl)oxy]benzoate
2 NADPH + 5 malonyl-CoA + 6 H+ + acetyl-CoA + oxygen → 2 NADP+ + 3 H2O + 5 CO2 + 6 coenzyme A + hexaketide pyrone
NADPH + H+ + (4S)-limonene + oxygen → H2O + NADP+ + (-)-trans-carveol
2-oxoglutarate + oxygen + gibberellin A37 → H2O + succinate + gibberellin A36 + CO2
NADH + H+ + oxygen + 2-propylphenol → H2O + 3-propylcatechol + NAD+
4S-hydroperoxy,17R-hydroxydocosahexaenoate → H2O + 4,5-epoxy-17R-hydroxy-docosahexaenoate
FADH2 + oxygen + 4-tyrosol → FAD + H2O + H+ + 3-hydroxytyrosol
2 H2O + 6 an oxidized ferredoxin [iron-sulfur] cluster + ammonium ← 6 a reduced ferredoxin [iron-sulfur] cluster + 8 H+ + nitrite
15 malonyl-CoA + 28 NADPH + 4 (S)-methylmalonyl-CoA + 47 H+ + 4-aminobenzoyl-CoA → 15 CO2 + 16 H2O + 20 coenzyme A + 28 NADP+ + candicinolide
2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + oxygen → H2O + 3-demethylubiquinol-9
YWA1 → H2O + nor-rubrofusarin
a reduced electron donor + oxygen + gibberellin A9 → 2 H2O + an oxidized electron donor + gibberellin A120
2 NADP+ + 1-chloro-4-hydroxylaminobenzene + H2O ← 2 NADPH + 2 H+ + 1-chloro-4-nitrobenzene
N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + oxygen → 2 H2O + isopenicillin N
an oxidized electron donor + H2O + N2 ← a reduced electron donor + nitrous oxide
1-(methylsulfanyl)-5-aci-nitropentane + glutathione → H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-ω-(methylsulfanyl)pentan-1-imine
dTDP-4-dehydro-6-deoxy-α-D-glucopyranose → H2O + dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose + H+
a reduced electron donor + oxygen + 4-ketotorulene → an oxidized electron donor + H2O + 3-hydroxy-4-ketotorulene
coumarinate + H+ → H2O + coumarin
coenzyme A + 3-hydroxypropanoate + NADPH + H+ + ATP → H2O + propanoyl-CoA + NADP+ + diphosphate + AMP
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + androst-4-ene-3,17-dione + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 1α-hydroxyandrost-4-ene-3,17-dione + H2O
2 FADH2 + 2,4,6-trichlorophenol + oxygen → 2 FAD + 3 H+ + H2O + 2,6-dichlorohydroquinone + chloride
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + androsta-1,4-diene-3,17-dione + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 9α-hydroxyandrosta-1,4-diene-3,17-dione + H2O
2 4-coumaroylagmatine + hydrogen peroxide → 2 H2O + hordatine A
NADH + H+ + 1,4-dimethylbenzene + oxygen → H2O + 4-methylbenzyl alcohol + NAD+
2'-N,N-dihydroxy-nocardicin c → H2O + nocardicin A
4 NADH + 4 oxygen + 6 H+ + dichlorochromopyrrolate → 2 CO2 + 4 NAD+ + 6 H2O + dichloro-arcyriaflavin A
2 H+ + 3 NAD(P)H + 3 oxygen + 4,4-dimethyl-5α-cholesta-8-en-3β-ol → 3 NAD(P)+ + 4 H2O + 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol
FMNH2 + oxygen + 22-[(1R,3S)-5,9,10-trihydroxy-1-methyl-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate → FMN + H2O + H+ + THN
NADPH + H+ + oxygen + demecolcine → H2O + formaldehyde + NADP+ + deacetylcolchicine
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + 3,5-dibromocatechol + 2,4-dibromophenol → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 2,4-dibromo-6-(2,4-dibromo-6-hydroxyphenoxy)phenol
2 NADPH + 2 bromide + 2 oxygen + 5 H+ + 4-hydroxybenzoate → 2 NADP+ + 4 H2O + 2,4-dibromophenol + CO2
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + butachlor + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + butyl formate + 2-chloro-N-(2,6-diethylphenyl)acetamide
FMNH2 + dibenzothiophene-5,5-dioxide + oxygen → FMN + H2O + 2'-hydroxybiphenyl-2-sulfinate
3-amino-1-hydroxyacetone 1-phosphate + 1-deoxy-D-xylulose 5-phosphate → 2 H2O + pyridoxine 5'-phosphate + H+ + phosphate
(2Z,4E)-2-amino-6-oxohexa-2,4-dienoate → H2O + picolinate
FAD + H2O + squalene + H+ ← FADH2 + hydroxysqualene
molybdopterin + H+ + MoO2-molybdopterin cofactor → H2O + bis(molybdenum cofactor)
2-((2-(1,3-dioxan-2-yl)ethyl)thio)-5-phenyl-1,3,4-oxadiazole + NADPH + H+ + oxygen → H2O + 2-[2-(1,3-dioxan-2-yl)ethanesulfinyl]-5-phenyl-1,3,4-oxadiazole + NADP+
5-(methylsulfanyl)-ribulose 1-phosphate → H2O + 2,3-diketo-5-methylthio-1-phosphopentane
2 3,5-dibromocatechol + 3 H+ + 4 a reduced ferredoxin [iron-sulfur] cluster + oxygen → 2 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + 3-bromo-5-(2,4-dibromo-6-hydroxyphenoxy)benzene-1,2-diol + bromide
FMNH2 + dimethyl sulfone + oxygen → 2 H+ + FMN + H2O + methanesulfinate + formaldehyde
6-deoxy-6-sulfo-D-gluconate → H2O + 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate
NADPH + H+ + oxygen + ethionamide → H2O + NADP+ + ethionamide S-oxide
NADPH + 9'-hydroxy-aurachin D + H+ + oxygen → H2O + aurachin RE + NADP+
NADPH + H+ + oxygen + 3-hydroxybenzoate → protocatechuate + H2O + NADP+
2 a reduced electron donor + 2 oxygen + 3-hydroxyechinenone → 2 an oxidized electron donor + 3 H2O + adonirubin
a reduced electron donor + 2-[hydroperoxy-(4-glucosyl-hydroxyphenyl)methyl]-6-hydroxy-1-benzofuran-3-one → an oxidized electron donor + H2O + 6-hydroxy-2-[(4-glucosyl-hydroxyphenyl)methyl]-1-benzofuran-3-one
4 a reduced electron donor + 4 oxygen + all-trans-4,4'-diapolycopene → 4 an oxidized electron donor + 6 H2O + 4,4'-diapolycopen-4,4'-dial
formate + H+ + ATP → H2O + dATP + CO2
3 H+ + NADPH + bromide + oxygen + 3-bromo-4,5-dihydroxybenzoate → 2 H2O + NADP+ + 3,5-dibromocatechol + CO2
NADPH + H+ + oxygen + 13-deoxycarminomycin → H2O + NADP+ + 13-dihydrocarminomycin
2 caldariellaquinol + 5 H+ + oxygen → 2 caldariellaquinone + 2 H2O + 5 H+
H+ + oxygen + protoviolaceinate → H2O + CO2 + proviolacein
Nω-phosphocreatine → H2O + creatinine + phosphate
2 H+ + 2,3-dihydroxybenzoate + NADH + oxygen → H2O + pyrogallol + NAD+ + CO2
cotinine + NADPH + H+ + oxygen → H2O + N'-hydroxymethyl-norcotinine + NADP+
10 malonyl-CoA + 14 NADPH + 23 H+ + acetyl-CoA → 10 CO2 + 11 coenzyme A + 14 NADP+ + 9 H2O + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate
NADPH + (E)-6-(methylsulfanyl)hexanal oxime + H+ + L-cysteine + oxygen → 2 H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)hexan-1-imine + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 3-chlorotoluene + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 3-chlorobenzyl alcohol
NADPH + H+ + oxygen + (S)-nicotine → H2O + 2'-hydroxynicotine + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + toluene + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + benzyl alcohol
L-threonine + 2-acetamido-2-deoxy-β-uronatemannosyl-(β1→4)-2,3-diacetamido-2,3-dideoxy-β-D-uronateglucosyl-(1→3)-N-acetyl-α-D-glucosaminyl-(C55 ω-saturated dolichyl phosphate) → H2O + 6-(L-threonyl)-2-acetamido-2-deoxy-β-uronatemannosyl-(1→4)-2,3-diacetamido-2,3-dideoxy-β-D-uronateglucosyl-(1→3)-N-acetyl-α-D-glucosaminyl-(C55 ω-saturated dolichyl phosphate)
5-deoxy-5-amino-3-dehydroquinate → H2O + 5-amino-5-deoxy-3-dehydroshikimate
protohypericin + a reduced electron donor + oxygen → 2 H2O + an oxidized electron donor + hypericin
4α-hydroxymethyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)H + H+ + oxygen → 2 H2O + 4α-formyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)+
2 (+)-sesamolinol + oxygen → 2 H2O + 2 (+)-sesamolin
NADPH + 4-hydroxyacetophenone + oxygen → H2O + (4-hydroxyphenyl)acetate + NADP+
2 3,5-dihydroxy-1,4-naphthoquinol + oxygen → 2 3,5-dihydroxy-1,4-naphthoquinone + 2 H2O + 2 H+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 flaviolin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 3,8'-biflaviolin
1-(3,4-dihydroxyphenyl)-3-(3-C-glucosyl-2,4,6-trihydroxyphenyl)propane-1,3-dione → H2O + orientin
2,5,7-trihydroxy-4'-methoxyisoflavanone → H2O + biochanin-A
2-keto-4-hydroxy-5-phosphopentanoate → H2O + 2-keto-5-phospho-3-cis-pentenoate
oxygen + 4-hydroxytetracenomycin A2 → H2O + tetracenomycin A2 epoxyquinone
NADPH + H+ + oxygen + neoabietadienol → H2O + NADP+ + neoabietadiene-diol
4 H+ + 2-methoxy-6-(all-trans-heptaprenyl)phenol + oxygen → H2O + 2-methoxy-6-all trans-heptaprenyl-1,4-benzoquinol
(S)-propane-1,2-diol → H2O + 1-propanal
propane-1,3-diamine + NADPH + oxygen → H2O + NADP+ + N-(3-aminopropyl)hydroxylamine
NADPH + H+ + andiconin + oxygen → H2O + NADP+ + andilesin D
progesterone + NADPH + H+ + oxygen → H2O + 17-α-hydroxyprogesterone + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:1-2-16:3-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:2-2-16:3-monogalactosyldiacylglycerol
phosphate + D-xylulose 5-phosphate → acetyl phosphate + H2O + D-glyceraldehyde 3-phosphate
formate + H+ + UTP → H2O + dUTP + CO2
formate + H+ + CTP → H2O + dCTP + CO2
2 NADPH + octadecanal + H+ + oxygen → 2 NADP+ + H2O + formate + heptadecane
NADPH + H+ + mycinamicin VIII + oxygen → H2O + NADP+ + mycinamicin VII
H2O + strombine + NAD+ ← glycine + NADH + pyruvate + H+
FADH2 + chloride + oxygen + D-tryptophan → 2 H2O + FAD + 6-chloro-D-tryptophan
2 hydroquinone + oxygen → 2 H2O + 2 1,4-benzoquinone
isoprene + NADH + H+ + oxygen → H2O + (3R)-3,4-epoxy-3-methylbut-1-ene + NAD+
NADH + H+ + oxygen + β-carotene → β-cryptoxanthin + H2O + NAD+
secologanate + tryptamine → H2O + (3αS,21S)-strictosidinate
2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one → H2O + 7,8-dihydroneopterin 3'-phosphate
N,N-dihydroxyhomomethionine + H+ → H2O + (E)-4-(methylsulfanyl)butanal oxime + CO2
2 a reduced ferredoxin [iron-sulfur] cluster + H+ + (25S)-26-oxocholest-4-en-3-one + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + (25S)-3-oxocholest-4-en-26-oate
NADH + 4-methylbenzoate + H+ + oxygen → H2O + 4-carboxybenzyl alcohol + NAD+
cis-3-hydroxy-L-proline → H2O + 1-pyrroline-2-carboxylate + H+
a reduced electron donor + dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-β-L-arabino-hexopyranose + oxygen → an oxidized electron donor + H2O + dTDP-β-L-evernitrose
4 coniferyl alcohol + oxygen → 2 H2O + 4 coniferyl alcohol radical
(9Z)-12,13-dihydroxyoctadeca-9-enoate + NADPH + H+ + oxygen → H2O + (9Z)-12,13,17-trihydroxyoctadeca-9-enoate + NADP+
2 NADPH + oleate + oxygen → 2 NADP+ + H2O + 18-hydroxyoleate
NADH + H+ + melilotate + oxygen → H2O + 3-(2,3-dihydroxyphenyl)propanoate + NAD+
2 H+ + 2 iodide + hydrogen peroxide → 2 H2O + I2
a reduced electron donor + oxygen + gibberellin A9 → an oxidized electron donor + H2O + gibberellin A40
2 H+ + 3 NADPH + 3 oxygen + 5β-cholestane-3α,7α,12α-triol → 3 NADP+ + 4 H2O + (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate
(+)-marmesin + NADPH + H+ + oxygen → 2 H2O + psoralen + acetone + NADP+
NAD(P)H + H+ + oxygen + (4'R)-11'-hydroxy-10'-methoxy-5'-azaspiro[cyclohexane-1,2'-tricyclo[6.3.1.04,��]dodecane]-'(12'),2,5,8',10'-pentaen-4-one → H2O + NAD(P)+ + formaldehyde + (4'R)-10',11'-dihydroxy-5'-azaspiro[cyclohexane-1,2'-tricyclo[6.3.1.04,��]dodecane]-'(12'),2,5,8',10'-pentaen-4-one
17β-estradiol + a reduced electron donor + oxygen → an oxidized electron donor + H2O + 6β-Hydroxyestradiol-17β
NAD(P)H + H+ + oxygen + dimeric rubrofusarin → H2O + NAD(P)+ + dimeric rubrofusarin-9-hydroxyrubrofusarin
formaldehyde + norfuraneol → H2O + 4-hydroxy-5-methyl-2-methylene-3(2H)-furanone
an oxidized ferredoxin [iron-sulfur] cluster + H2O + benzoyl-CoA ← 2 H+ + a reduced ferredoxin [iron-sulfur] cluster + 4-hydroxybenzoyl-CoA
2-oxoglutarate + H+ + chloride + oxygen + hapalindole U → H2O + succinate + hapalindole G + CO2
ent-isokaurene + NADPH + H+ + oxygen → H2O + ent-isokauren-2α-ol + NADP+
NADPH + H+ + oxygen + 7,10-diketo-pre-bikaverin → H2O + NADP+ + 6-hydroxy-norbikaverin
1-(2-aminophenyl)decane-1,3-dione → H2O + 2-heptyl-4-quinolone
an oxidized electron donor + H+ + betalamate + 2-descarboxy-cyclo-dopa → H2O + a reduced electron donor + 2-descarboxy-betanidin
NAD(P)H + 4α-methyl-5α-cholesta-8-en-3-ol + H+ + oxygen → 4α-hydroxymethyl-5α-cholesta-8-en-3β-ol + H2O + NAD(P)+
NADPH + H+ + 4-hydroxybenzoate + oxygen → protocatechuate + H2O + NADP+
4-hydroxyzeaxanthin + a reduced electron donor + oxygen → an oxidized electron donor + 4,4-dihydroxyzeaxanthin + H2O
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-linoleoyl-2-palmitoyl-phosphatidylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-α-linolenoyl-2-palmitoyl-phosphatidylglycerol
3-dehydroshikimate → protocatechuate + H2O
cotinine + NADPH + H+ + oxygen → H2O + NADP+ + trans-3'-hydroxycotinine
NADH + H+ + oxygen + (-)-α-pinene → α-pinene oxide + H2O + NAD+
NADPH + H+ + 3-decaprenyl-4-hydroxybenzoate + oxygen → 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + H2O + NADP+
NADH + 2,4,5-trichloro-phenoxyacetate + oxygen → H2O + glyoxylate + NAD+ + 2,4,5-trichlorophenol
L-tyrosine + betalamate → H2O + H+ + portulacaxanthin II
0.5 oxygen + 5,10-dihydro-9-dimethylallylphenazine 1-carboxylate → H2O + endophenazine A
9-hydroxy-3,5,7,11,13,15,17,19-octaoxohenicosanoyl-[acp] → 4 H2O + 12-deoxyaklanoate
progesterone + a reduced electron donor + oxygen → an oxidized electron donor + H2O + testosterone acetate
2 H2O + an oxidized electron donor + OH- + trithionate ← 3 hydrogensulfite + a reduced electron donor
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-linoleoyl-2-(3E)-hexadecenoyl-phosphatidylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-α-linolenoyl-2-(3E)-hexadecenoyl-phosphatidylglycerol
5β-cholestane-3α,7α,12α-triol + NADPH + H+ + oxygen → H2O + (25R)-5β-cholestane-3α,7α,12α,26-tetraol + NADP+
NADPH + ethanol + H+ + oxygen → 2 H2O + acetaldehyde + NADP+
FMNH2 + oxygen + medermycin → FMN + H2O + H+ + mederrhodin A
a reduced electron donor + 2,4,6-trinitrotoluene → an oxidized electron donor + H2O + 2-methyl-1,5-dinitro-3-nitrosobenzene
2-((1R,3S),-1',9'-dihydroxy-1'-methyl-10'-oxo-3',4',5',10'-tetrahydro-1H-benzo[g]isochromen-3'-yl)acetate → H2O + (S)-DNPA
NADPH + H+ + oxygen + ethionamide S-oxide → H2O + NADP+ + (2-ethylpyridin-4-yl)(imino)methanesulfinate
glutathione + 1-aci-nitro-2-(4-hydroxyphenyl)ethane → H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-2-(4-hydroxyphenyl)ethan-1-imine
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-18:2-digalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:2-2-18:3-digalactosyldiacylglycerol
a reduced electron donor + C27-mycolipanoyl-CoA + oxygen → 2 H2O + an oxidized electron donor + C27-mycolipenyl-CoA
2-oxoglutarate + oxygen + (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate → H2O + succinate + (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate + CO2
NADPH + H+ + mycinamicin IV + oxygen → H2O + NADP+ + mycinamicin V
2 NAD(P)H + 2 H+ + oxygen → 2 H2O + 2 NAD(P)+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-18:3-digalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-18:3-digalactosyldiacylglycerol
2-oxoglutarate + oxygen + gibberellin A51 → H2O + H+ + succinate + gibberellin A51-catabolite + CO2
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:1-2-16:1-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:2-2-16:1-monogalactosyldiacylglycerol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:1-2-16:0-digalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:2-2-16:0-digalactosyldiacylglycerol
NADPH + oxygen + elymoclavine aldehyde → H2O + NADP+ + paspalate
calcitriol + NADPH + H+ + oxygen → H2O + NADP+ + calcitetrol
hydroxylamine + pyruvate → H2O + pyruvic oxime
an oxidized electron donor + H2O + selenite ← a reduced electron donor + selenate
pregnenolone + NADPH + H+ + oxygen → H2O + 17-α-hydroxypregnenolone + NADP+
a reduced electron donor + oxygen + 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol → an oxidized electron donor + H2O + 3-demethylubiquinol-6
3 H+ + 3 malonyl-CoA + H2O + acetyl-CoA → 3 CO2 + 4 coenzyme A + H2O + orsellinate + H+
2 5-aminolevulinate → 2 H2O + porphobilinogen + H+
2-(hydroxylamino)benzoyloctanoate → H2O + 2-n-heptyl-4-hydroxyquinoline-N-oxide
3-methylxanthine + NADH + H+ + oxygen → xanthine + H2O + formaldehyde + NAD+
2 oxygen + 4 a reduced ferredoxin [iron-sulfur] cluster + 4 H+ + zeaxanthin → 2 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + violaxanthin
(3R)-3-hydroxy-behenoyl-CoA → H2O + trans-docos-2-enoyl-CoA
FMNH2 + 2-methylpropan-1-amine + oxygen → 2 H+ + FMN + H2O + N-(2-methylpropyl)hydroxylamine
trans-4-hydroxy-L-proline → H2O + H+ + (S)-1-pyrroline-5-carboxylate
2-oxo-3-(phosphooxy)propyl 8-methyl-3-oxononanoate → H2O + [4-(6-methylheptanoyl)-5-oxo-2H-furan-3-yl]methyl phosphate
2 H+ + 3 NADH + 3 oxygen + 4,4-dimethyl-5α-cholesta-8-en-3β-ol → 3 NAD+ + 4 H2O + 4β-carboxy-4α-methyl-5α-cholesta-8-en-3β-ol
2 H+ + cyclo-dopa glucuronosyl glucoside + betalamate → H2O + amaranthin
(+)-isopimara-7,15-diene + NADPH + H+ + oxygen → H2O + NADP+ + isopimara-7,15-dienol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:1-2-16:2-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:2-2-16:2-monogalactosyldiacylglycerol
a reduced electron donor + oleoyl-CoA + oxygen → 2 H2O + an oxidized electron donor + linoleoyl-CoA
FADH2 + NAD(P)H + flavin-C4a-peroxide + trans-hexenoyl-CoA + oxygen → FAD + H2O + NAD(P)+ + flavin-C4a-hydroxide + trans-2,3-epoxyhexanoyl-CoA
NAD(P)H + H+ + oxygen + rubrofusarin → H2O + NAD(P)+ + 9-hydroxyrubrofusarin
H+ + oxygen + 6-methoxy-3-methyl-2-all-trans-nonaprenyl-1,4-benzoquinol → H2O + 3-demethylubiquinol-9
2 2-oxoglutarate + 2 oxygen + pentalenolactone D → 2 succinate + 2 CO2 + H2O + pentalenolactone F
NADPH + H+ + oxygen + (+)-epi-isozizaene → H2O + (5R)-albaflavenol + NADP+
2 oxygen + α-fenchene → H2O + α-fenchocamphorone + CO2
3,4-dihydroxy-2-methyl-4-farnesyl-3H-quinolin-1-ium-1-olate → H2O + aurachin B
NADPH + H+ + mycinamicin V + oxygen → H2O + NADP+ + mycinamicin II
NADPH + H+ + oxygen + previridicatumtoxin → 2 H2O + NADP+ + viridicatumtoxin
NAD(P)H + 4-keto-2-undecyl-4,5-dihydropyrrole → H2O + NAD(P)+ + 2-undecylpyrrole
(+)-pulegone + NADPH + H+ + oxygen → 2 H2O + (+)-menthofuran + NADP+
2 NADH + 2 H+ + 2 oxygen + β-carotene → 2 H2O + 2 NAD+ + zeaxanthin
4 L-ascorbate + 4 H+ + oxygen → 2 H2O + 4 monodehydroascorbate radical
2 ethylsulfenate → H2O + diethyl thiosulfinate
FMNH2 + 5-deoxy-dihydrokalafungin + oxygen → FMN + H2O + H+ + 22-[(1R,3S)-5,9,10-trihydroxy-1-methyl-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate
2 H+ + anthranilate + oxygen → H2O + 3-hydroxyanthranilate
12 H+ + 5 NADPH + 6 malonyl-CoA + NADH → 4 H2O + 5 NADP+ + 6 coenzyme A + 6 CO2 + (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + NAD+
a reduced electron donor + deoxyhumulone + oxygen → an oxidized electron donor + H2O + humulone
cholesterol + NADPH + H+ + oxygen → H2O + NADP+ + 7α-hydroxycholesterol
NADH + H+ + salicyl-CoA + oxygen → H2O + NAD+ + gentisyl-CoA
11 ATP + 2 N5-formyl-N5-hydroxy-L-ornithine + 2 L-threonine + 2 L-serine + L-tyrosine + L-lysine + L-glutamate + L-2,4-diaminobutanoate + L-arginine → 11 diphosphate + 11 AMP + 12 H+ + ferribactin + H2O
3 oxygen + 5 H+ + 6 a reduced ferredoxin [iron-sulfur] cluster + cholest-4-en-3-one → 4 H2O + 6 an oxidized ferredoxin [iron-sulfur] cluster + (25R)-3-oxocholest-4-en-26-oate
H+ + betalamate + cyclo-dopa 5-O-glucoside → H2O + betanin
a reduced electron donor + oxygen + 3-hydroxybenzoate → an oxidized electron donor + 2,3-dihydroxybenzoate + H2O
7-dehydrocholesterol + NADPH + H+ + oxygen → H2O + NADP+ + 7-ketocholesterol
2 (E) 1-propenylsulfenate + H+ → H2O + thiosulfinate
N, N-dihydroxy-tetrahomomethionine + H+ → H2O + (E)-7-(methyltsulfanyl)heptanal oxime + CO2
NADPH + kauralexin B3 + oxygen → H2O + kauralexin B2 + NADP+
octanoate + schizokinen + H+ → H2O + rhizobactin 1021
NAD(P)H + choline + H+ + oxygen → H2O + NAD(P)+ + glycolaldehyde + trimethylamine
FADH2 + L-tryptophan + chloride + oxygen → 2 H2O + FAD + 7-chloro-L-tryptophan
a reduced electron donor + atrazine + oxygen → an oxidized electron donor + H2O + deethylatrazine + acetaldehyde
glycerone phosphate + 2-iminosuccinate → 2 H2O + quinolinate + phosphate
NADPH + H+ + oxygen + desmethylanthrotainin → H2O + NADP+ + 5-hydroxy-desmethylanthrotainin
isocryptoxanthin + a reduced electron donor + oxygen → an oxidized electron donor + 4,4-dihydroxy-β,β-carotene + H2O
13(S)-HPOTE → (ω5Z)-etherolenate + H2O
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:3-2-16:0-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-16:1-monogalactosyldiacylglycerol
ethene + NADH + H+ + oxygen → H2O + ethylene oxide + NAD+
hydrogen peroxide + H+ + harderoheme III → 2 H2O + protoheme + CO2
1-(methylsulfanyl)-9-aci-nitrononane + glutathione → H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-ω-(methylsulfanyl)nonan-1-imine
4 H+ + 4 Cu+ + oxygen → 2 H2O + 4 Cu2+
4α-formyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen → H2O + NAD(P)+ + 4α-carboxy-5α-cholesta-8-en-3β-ol
3-(2-formyl-6-hydroxy-4-methylphenyl)-8-hydroxy-1,4-dioxonaphthalene-2-carboxylate + L-isoleucine → H2O + (3aS)-jadomycin A + CO2
a reduced electron donor + 18-carboxy candicinolide + oxygen → an oxidized electron donor + H2O + demycosaminyl-candicidin III
a reduced electron donor + 2-(hydroxysulfanyl)hercynine → an oxidized electron donor + H2O + ergothioneine
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:1-2-16:0-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:1-2-16:1-monogalactosyldiacylglycerol
2 NADPH + 2 H+ + 2 oxygen + echinocandin D → 2 H2O + 2 NADP+ + echinocandin C
hercynine + oxygen + γ-L-glutamyl-L-cysteine → H2O + γ-L-glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide
4-nitrophenol + NAD(P)H + H+ + oxygen → H2O + 1,4-benzoquinone + NAD(P)+ + nitrite
(S)-lactate + oxygen → acetate + H2O + CO2
3 oxygen + 5 H+ + 6 a reduced ferredoxin [iron-sulfur] cluster + cholest-4-en-3-one → 4 H2O + 6 an oxidized ferredoxin [iron-sulfur] cluster + (25S)-3-oxocholest-4-en-26-oate
methamphetamine + NADPH + oxygen → H2O + N-methyl-N-[(2S)-1-phenylpropan-2-yl]hydroxylamine + NADP+
2 oxygen + 4 a reduced ferredoxin [iron-sulfur] cluster + 4 H+ + β-carotene → 2 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + zeaxanthin
4,4'-diapolycopene-4-al + a reduced electron donor + oxygen → an oxidized electron donor + 4'-hydroxy-4,4'-diapolycopen-4-al + H2O
2 NADPH + 2 oxygen + 3 H+ + chlorophyllide a → 2 NADP+ + 3 H2O + chlorophyllide b
a reduced electron donor + oxygen + echinenone → an oxidized electron donor + H2O + 3-hydroxyechinenone
NADPH + H+ + oxygen + furostanol-26-alcohol → 2 H2O + NADP+ + furostanol-26-aldehyde
2 H+ + NADH + 4-chlorosalicylate + oxygen → H2O + NAD+ + 4-chlorocatechol + CO2
a reduced electron donor + isourolithin A → an oxidized electron donor + H2O + urolithin B
L-ornithine + NADPH + oxygen → H2O + N5-hydroxy-L-ornithine + NADP+
NADH + H+ + oxygen + 3-hydroxy-5-methyl-benzoate → H2O + NAD+ + 3-methylgentisate
hydrogen peroxide + a reduced electron donor → 2 H2O + an oxidized electron donor
NADH + H+ + oxygen + (3S,3'S)-astaxanthin → H2O + NAD+ + 2-hydroxyastaxanthin
a reduced electron donor + urolithin A → an oxidized electron donor + H2O + urolithin B
NADPH + 1,6,8-trihydroxy-1H,3H-cyclohepta[c]furan-5-one + oxygen → 2 H2O + stipitalide + NADP+
NADPH + (E)-8-(methylsulfanyl)octanal oxime + H+ + L-cysteine + oxygen → 2 H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)octan-1-imine + NADP+
4,4-dimethyl-5α-cholesta-8-en-3β-ol + NAD(P)H + H+ + oxygen → 4α-hydroxymethyl-4β-methyl-5α-cholesta-8-en-3β-ol + H2O + NAD(P)+
2-oxoglutarate + H+ + oxygen + luteoforol → 2 H2O + luteolinidin + succinate + CO2
2 NADH + 2 H+ + carbon disulfide + oxygen → 2 NAD+ + H2O + hydrogen sulfide + carbonyl sulfide
L-alanine + ATP + fumiquinazoline F-indoline-2',3'-diol → H2O + H+ + diphosphate + AMP + fumiquinazoline A
a reduced electron donor + urate + oxygen → an oxidized electron donor + H2O + (S)-5-hydroxyisourate
NADPH + H+ + hydroxyversicolorone + oxygen → H2O + NADP+ + versiconal hemiacetal acetate
2,3-seco-dopa → H2O + (4Z)-4-[(2E)-3-carboxylato-3-hydroxyprop-2-en-1-ylidene]-3,4-dihydro-2H-pyrrole-2-carboxylate + H+
NADPH + oxygen + tryptamine → H2O + N-hydroxyl-tryptamine + NADP+
NAD(P)H + 3-methylxanthine + H+ + oxygen → xanthine + H2O + NAD(P)+ + formaldehyde
2 H+ + 1-hydroxy-2-naphthoate + NAD(P)H + oxygen → H2O + naphthalene-1,2-diol + NAD(P)+ + CO2
a reduced electron donor + H+ + perchlorate → 2 H2O + an oxidized electron donor + chlorite
8-methyl-6-nonenoate + coniferyl alcohol + H+ → H2O + capsiconiate
2 H+ + 3 NAD(P)H + 3 oxygen + 4,4-dimethyl-5α-cholest-7-en-3β-ol → 3 NAD(P)+ + 4 H2O + 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate
FADH2 + 7-chloro-L-tryptophan + chloride + oxygen → 2 H2O + FAD + 6,7-dichloro-L-tryptophan
spheroidene + a reduced ferredoxin [iron-sulfur] cluster + oxygen → an oxidized ferredoxin [iron-sulfur] cluster + H2O + spheroiden-2-one
mycothiol + arsenate → H2O + mycothiol-arsenate conjugate
NADPH + H+ + 3-chlorophenol + oxygen → H2O + NADP+ + 3-chlorocatechol
5-dehydro-4-deoxy-D-glucarate + H+ → H2O + 2,5-dioxopentanoate + CO2
2 oxygen + a reduced electron donor + arachidonate → an oxidized electron donor + H2O + prostaglandin-H2
2 indoxyl + oxygen → 2 H2O + indigo
NADPH + H+ + oxygen + decarboxy-dehydroxy-demycosaminyl-nystatin → H2O + NADP+ + decarboxy-demycosaminyl-nystatin
L-cysteine + indole-3-carbinol → H2O + indol-3-ylmethyl-L-cysteine
2 NADH + 2 H+ + oxygen → 2 H2O + 2 NAD+
propane + NADH + H+ + oxygen → H2O + propan-2-ol + NAD+
quinolin-4-ol + NADH + H+ + oxygen → H2O + quinolin-3,4-diol + NAD+
NADPH + H+ + benzoyl-CoA + oxygen → H2O + NADP+ + salicyl-CoA
NAD(P)H + H+ + linoleate + oxygen → 2 H2O + crepenynate + NAD(P)+
(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA → H2O + (2E,11Z,14Z,17Z)-icosatetraenoyl-CoA
FMNH2 + (1S)-bornane-2,5-dione + oxygen → FMN + H2O + (-)-5-oxo-1,2-campholide + H+
2 (Z,Z)-bilirubin-IX α + oxygen → 2 H2O + 2 (Z,Z)-biliverdin-IX α
L-serine → H2O + H+ + 2-aminoprop-2-enoate
butein 4'-β-D-glucoside + a reduced electron donor + oxygen → 2 H2O + an oxidized electron donor + sulfuretin 6-glucoside
NADPH + H+ + taurochenodeoxycholate + oxygen → H2O + NADP+ + taurohyocholate
dimethyl sulfoxide + NADPH + H+ + oxygen → H2O + dimethyl sulfone + NADP+
(+)-bornane-2,5-dione + NADH + H+ + oxygen → H2O + (+)-5-oxo-1,2-campholide + NAD+
NADPH + H+ + oxygen + (-)-menthol → H2O + (1R,3R,4R)-p-menthane-3,8-diol + NADP+
hydrogen peroxide + 3-methyl-L-tyrosine → H2O + 3-hydroxy-5-methyl-L-tyrosine
glycine + a reduced electron donor + phosphate + ADP → an oxidized electron donor + ammonia + acetate + H2O + ATP
H2O + sulfonopine + NADP+ ← NADPH + pyruvate + H+ + S-methyl-L-methionine
NAD(P)H + H+ + oxygen + protodeoxyviolaceinate → H2O + NAD(P)+ + deoxyviolaceinate
L-ascorbate + 4-hydroxyamphetamine + H+ + oxygen → H2O + L-dehydro-ascorbate + 4-hydroxynorephedrine
NADPH + H+ + leukotriene-E4 + oxygen → H2O + NADP+ + 20-hydroxy-leukotriene-E4
12-ethyl-71,71-dihydroxy-8-isobutylbacteriochlorophyllide c → H2O + 12-ethyl-8-isobutylbacteriochlorophyllide e
8,8a-deoxyoleandolide + oxygen → H2O + oleandolide
2 trans-4-hydroxy-L-proline + oxygen → 2 H2O + 2 (3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate + 2 H+
NAD(P)H + caffeine + H+ + oxygen → H2O + NAD(P)+ + theobromine + formaldehyde
all-trans-phytoene + a reduced electron donor + oxygen → all-trans phytofluene + an oxidized electron donor + 2 H2O
reduced reactive black 5 + hydrogen peroxide → 2 H2O + oxidized reactive black 5
13 NADPH + 21 H+ + 9 malonyl-CoA + acetyl-CoA → 10 coenzyme A + 13 NADP+ + 8 H2O + 9 CO2 + (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate
(+)-dihydrokaempferol + NADPH + oxygen → H2O + (+)-taxifolin + NADP+
4α-hydroxymethyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + H+ + oxygen → 2 H2O + 4α-formyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+
NADPH + H+ + α-tocopherol + oxygen → H2O + 13'-hydroxy-α-tocopherol + NADP+
NADPH + H+ + benzoyl-CoA + oxygen → H2O + 2,3-epoxy-2,3-dihydrobenzoyl-CoA + NADP+
H2O + 13(S)-HOT + NADP+ ← NADPH + H+ + 13(S)-HPOTE
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-16:2-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:2-2-16:3-monogalactosyldiacylglycerol
2-oxoglutarate + H+ + chloride + oxygen + ambiguine C → H2O + succinate + ambiguine B + CO2
a reduced electron donor + urolithin M7 → an oxidized electron donor + H2O + urolithin A
a reduced electron donor + urolithin M5 → an oxidized electron donor + H2O + urolithin D
a reduced electron donor + urolithin C → an oxidized electron donor + H2O + urolithin A
3-dehydroquinate + H+ + ammonium → 4 H2O + 4-aminobenzoate
12 H+ + 6 NADPH + 6 (S)-methylmalonyl-CoA + acetyl-CoA → 6 NADP+ + 6 CO2 + 7 coenzyme A + H2O + 8,8a-deoxyoleandolide
NAD(P)H + H+ + preaspyridone A + oxygen → 2 H2O + NAD(P)+ + aspyridone A
4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NADPH + H+ + oxygen → 2 H2O + 4,4-dimethyl-14α-formyl-5α-cholesta-8-en-3β-ol + NADP+
(3R,11Z,14Z)-3-hydroxyicosadienoyl-CoA → H2O + (2E,11Z,14Z)-icosatrienoyl-CoA
2-hydroxy-2-(1H-indol-3-yl)acetonitrile → H2O + dehydro(indole-3-yl)acetonitrile
1-propanal + norfuraneol → H2O + (2E)-4-hydroxy-5-methyl-2-propylidene-3(2H)-furanone
diadinoxanthin + L-ascorbate + H+ → diatoxanthin + H2O + L-dehydro-ascorbate
H2O + MMF2 butenolide intermediate → H2O + methylenomycin furan 2
2-[(3'-methylsulfanyl)propyl]malate → H2O + 2-[(2'-methylsulfanyl)propyl]maleate
a reduced electron donor + oxygen + (indol-3-yl)acetate → an oxidized electron donor + H2O + indole-3-glycolate
2 H+ + NADPH + oxygen + 4-hydroxyisophthalate → protocatechuate + H2O + NADP+ + CO2
3 H+ + NADPH + 4-coumarate + oxygen → H2O + NADP+ + trans-caffeate
2 H2 + oxygen → 2 H2O
UWM6 → H2O + prejadomycin
NADPH + H+ + oxygen + magnesium-protoporphyrin IX 13-monomethyl ester → H2O + NADP+ + 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester
15 malonyl-CoA + 19 NADPH + 3 (S)-methylmalonyl-CoA + 37 H+ + acetyl-CoA → 18 CO2 + 19 coenzyme A + 19 NADP+ + 8 H2O + decarboxy-dehydroxy-demycosaminyl-nystatin
a reduced electron donor + oxygen + lubimin → an oxidized electron donor + H2O + 3-hydroxylubimin
2-oxoglutarate + oxygen + gibberellin44 (open lactone form) → H2O + succinate + gibberellin A19 + CO2
FADH2 + 2,5-dichloro-p-quinol + oxygen → 3 H+ + FAD + H2O + 5-chlorohydroxyquinone + chloride
hydrogen peroxide + H+ + Fe-coproporphyrin III → 2 H2O + harderoheme III + CO2
2 NADPH + 2 H+ + 7,2'-dihydroxy-4'-methoxyisoflavan + oxygen → 2 NADP+ + H2O + 10,2'-dihydroxy-4'-methoxy-isoflav-8-ene-7-one
2 a reduced ferredoxin [iron-sulfur] cluster + 2 2,4-dibromophenol + H+ + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 2,4-dibromo-6-(2,4-dibromophenoxy)phenol
GDP-α-D-mannose → GDP-4-dehydro-α-D-rhamnose + H2O
proclavaminate + 2-oxoglutarate + oxygen → H2O + dihydroclavaminate + succinate + CO2
hercynine + L-selenocysteine + oxygen → H2O + hercynylselenocysteine
(3R,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosapentaenoyl-CoA → (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H2O
3 cadaverine + 4 pyruvate → 3 H2O + 4 L-alanine + 17-oxosparteine + H+
2 NADPH + 2 H+ + 2 L-arginine + 2 oxygen → 2 H2O + 2 NADP+ + 2 Nω-hydroxy-L-arginine
NADPH + H+ + oxygen + 71-hydroxychlorophyllide a → 2 H2O + NADP+ + chlorophyllide b
H2O + D-nopaline + NADP+ ← NADPH + 2-oxoglutarate + H+ + L-arginine
NADH + H+ + (25S)-26-hydroxycholest-4-en-3-one + oxygen → 2 H2O + NAD+ + (25S)-26-oxocholest-4-en-3-one
L-dopa + L-tyrosine + oxygen → dopaquinone + H2O + L-dopa
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + canthaxanthin → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + adonirubin
NAD(P)H + H+ + aminopyrrolnitrin + oxygen → H2O + N-[2-chloro-6-(4-chloro-1H-pyrrol-3-yl)phenyl]hydroxylamine + NAD(P)+
NADH + H+ + dibenzothiophene-5-oxide + oxygen → H2O + dibenzothiophene-5,5-dioxide + NAD+
2 anthranilate + 3 ATP + L-tryptophan → 3 diphosphate + 3 AMP + H2O + H+ + asperlicin D
2 anthranilate + 3 ATP + L-tryptophan → 3 diphosphate + 3 AMP + H2O + H+ + asperlicin C
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-16:0-2-18:2-digalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-16:0-2-18:3-digalactosyldiacylglycerol
2 NADPH + 2 H+ + 2-nitrobenzoate → 2 NADP+ + H2O + 2-hydroxylaminobenzoate
3 glycine + 3 N5-acetyl-N5-hydroxy-L-ornithine + 3 ATP + Fe3+ → 3 H2O + 3 diphosphate + 3 AMP + 6 H+ + ferrichrome
17-α-hydroxyprogesterone + NADPH + oxygen → androst-4-ene-3,17-dione + acetate + H2O + NADP+
1,3,6,8-naphthalenetetrol + oxygen → H2O + H+ + flaviolin
NADPH + putrescine + oxygen → N-hydroxyputrescine + H2O + NADP+
7β-hydroxy-3-oxochol-4-en-24-oyl-CoA → H2O + 3-oxochol-4,6-dien-24-oyl-CoA
7α-hydroxy-3-oxochol-4-en-24-oyl-CoA → H2O + 3-oxochol-4,6-dien-24-oyl-CoA
H2O + NAD+ + nitrous oxide ← 2 nitric oxide + NADH + H+
NADPH + H+ + 4-chlorophenol + oxygen → H2O + NADP+ + 4-chlorocatechol
hydrogen peroxide + H+ + linoleate → 2 H2O + 1E,8Z,11Z-heptadecatriene + CO2
(+)-taxifolin + 2-oxoglutarate + oxygen → H2O + quercetin + succinate + CO2
FMNH2 + EDTA + oxygen → FMN + H2O + ethylenediaminetriacetate + glyoxylate + H+
4 H+ + 6-(all-trans-decaprenyl)-2-methoxy-phenol + oxygen → H2O + all trans-decaprenyl-2-methoxy-6-1,4-benzoquinol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-16:3-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-16:3-monogalactosyldiacylglycerol
H2O + MMF5 butenolide intermediate → H2O + methylenomycin furan 5
NAD(P)H + H+ + (-)-medicarpin + oxygen → H2O + NAD(P)+ + 1α-hydroxy-medicarpin
(5S)-HPETE → H2O + leukotriene A4
NAD(P)H + paraxanthine + H+ + oxygen → 7-methylxanthine + H2O + NAD(P)+ + formaldehyde
violaxanthin + L-ascorbate + H+ → antheraxanthin + H2O + L-dehydro-ascorbate
(6R)-4a-hydroxy-tetrahydrobiopterin → H2O + L-erythro-7,8-dihydrobiopterin
N,N-dimethylaniline + NADPH + H+ + oxygen → H2O + N,N-dimethylaniline-N-oxide + NADP+
H2O + alanopine + NAD+ ← NADH + pyruvate + H+ + L-alanine
NADH + H+ + oxygen + 4-hydroxyprotoasukamycin → H2O + NAD+ + asukamycin
NADPH + H+ + (+)-menthone + oxygen → H2O + NADP+ + (4S,7R)-7-isopropyl-4-methyloxepan-2-one
malonate + afrormosin-7-O-glucoside + H+ → H2O + afrormosin-7-O-glucoside-6''-O-malonate
a reduced electron donor + isethionate + oxygen → 2 H2O + an oxidized electron donor + sulfoacetaldehyde
3 H+ + NADPH + bromide + oxygen + 3-bromo-4-hydroxybenzoate → 2 H2O + NADP+ + 2,4-dibromophenol + CO2
14-demethyllanosterol + NAD(P)H + H+ + oxygen → 4α-hydroxymethyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + H2O + NAD(P)+
H2O + NADP+ + nitrosobenzene ← NADPH + H+ + nitrobenzene
L-homoserine → H2O + H+ + (2Z)-2-aminobut-2-enoate
2 H+ + 2-nonaprenylphenol + oxygen → H2O + 3-(all-trans-nonaprenyl)benzene-1,2-diol
NADPH + H+ + oxygen + 8-O-methyl-5-hydroxy-fusarubinaldehyde → H2O + NADP+ + 8-O-methyl-5,10-dihydroxy-fusarubinaldehdye
NADPH + (25R)-3α,7α-dihydroxy-5β-cholestan-26-al + oxygen → H2O + (25R)-3α,7α-dihydroxy-5-β-cholestanate + NADP+
hydrogen peroxide + dehydro-D-arabinono-1,4-lactone → H2O + dehydro-erythro-ascorbate
2-oxoglutarate + oxygen + pentalenolactone D → H2O + succinate + pentalenolactone E + CO2
2 H+ + 3 NAD(P)H + 3 oxygen + 14-demethyllanosterol → 3 NAD(P)+ + 4 H2O + 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol
cholesterol + a reduced electron donor + oxygen → an oxidized electron donor + H2O + 25-hydroxycholesterol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2-hydroxyspirilloxanthin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2,2-dihydroxyspirilloxanthin + H2O
a reduced electron donor + oxygen + 5-pentadecatrienyl resorcinol-3-methyl ether → an oxidized electron donor + H2O + dihydrosorgoleone
NADPH + dTDP-N-hydroxy-β-L-evernosamine + H+ + oxygen → 2 H2O + NADP+ + dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-β-L-arabino-hexopyranose
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:3-2-16:2-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-16:3-monogalactosyldiacylglycerol
(2R,6Z)-2-hydroxy-6-(hydroxymethylidene)-2,5-dimethylcyclohex-4-ene-1,3-dione + 2-oxoglutarate + oxygen → H2O + stipitaldehyde + succinate + CO2
H2O + (S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ ← NAD(P)H + H+ + (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
H+ + emodin + emodin anthrone → H2O + emodin dianthrone
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + 1-deoxypentalenate → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + pentalenate
2 3-(7-chloroindol-3-yl)-2-iminopropanoate + hydrogen peroxide → 2 H2O + 3,4-bis(7-chloro-1H-indol-3-yl)-2,5-diiminohexanedioate
FADH2 + (3Z,5S,6E,8E,10E)-1-aminododeca-3,6,8,10-tetraen-5-ol + oxygen → FAD + H2O + (1E,3S,4Z)-7-amino-1-{3-[(1E)-prop-1-en-1-yl]oxiran-2-yl}hepta-1,4-dien-3-ol + H+
1-(methylsulfanyl)-8-aci-nitrooctane + glutathione → H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-ω-(methylsulfanyl)octan-1-imine
2 3,5-dibromocatechol + 3 H+ + 4 a reduced ferredoxin [iron-sulfur] cluster + oxygen → 2 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + 5-bromo-3-(3,5-dibromo-2-hydroxyphenoxy)benzene-1,2-diol + bromide
(3R)-3-hydroxyoctadecanoyl-CoA → H2O + (2E)-octadec-2-enoyl-CoA
2 3,5-dibromocatechol + 3 H+ + 4 a reduced ferredoxin [iron-sulfur] cluster + oxygen → 2 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + 5-bromo-3-(2,4-dibromo-6-hydroxyphenoxy)benzene-1,2-diol + bromide
CMP-5'-3-(aminopropyl)phosphonate + NADPH + oxygen → H2O + CMP-5'-N-hydroxy-3-(aminopropyl)phosphonate + NADP+
pentane + NADH + H+ + oxygen → H2O + pentan-1-ol + NAD+
a reduced electron donor + β-peltatin-A methyl ether + oxygen → an oxidized electron donor + 6-methoxypodophyllotoxin + H2O
2 a reduced electron donor + 2 oxygen + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate → 2 an oxidized electron donor + 2 H2O + 17S-hydroperoxydocosahexaenoate
cyclooctat-9-en-7-ol + a reduced electron donor + oxygen → an oxidized electron donor + cyclooctat-9-en-5,7-diol + H2O
p-coumaroyltriacetate → H2O + p-coumaroyltriacetic acid lactone
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + 2'-hydroxy-2-oxospirilloxanthin → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 2',2'-dihydroxy-2-oxospirilloxanthin
2 3-amino-4-hydroxybenzaldehyde + an oxidized electron donor + N-acetyl-L-cysteine + oxygen → 2 H2O + a reduced electron donor + grixazone A
(4-hydroxyphenyl)acetate + NAD(P)H + H+ + oxygen → H2O + homogentisate + NAD(P)+
vanillate + NADH + H+ + oxygen → protocatechuate + H2O + formaldehyde + NAD+
H2O + NADP+ + (+)-gallocatechin ← NADPH + H+ + (2R,3S,4S)-leucodelphinidin
χ,χ-caroten-18-oate + a reduced electron donor + oxygen → an oxidized electron donor + 18'-hydroxy-χ,χ-caroten-18-oate + H2O
2-oxoglutarate + H+ + oxygen + gibberellin44 (open lactone form) → H2O + succinate + gibberellin A38 + CO2
2 N-hydroxy-N-succinylcadaverine + N-hydroxy-N-acetylcadaverine + ATP → H2O + desferrioxamine B + H+ + diphosphate + AMP
NADH + H+ + cholest-4-en-3-one + oxygen → H2O + NAD+ + (25S)-26-hydroxycholest-4-en-3-one
CDP-α-D-glucose → H2O + CDP-4-dehydro-6-deoxy-α-D-glucose
FADH2 + 3,5,6-trichloro-2-pyridinol + oxygen → 2 H+ + FAD + H2O + 3,6-dichloropyridine-2,5-dione + chloride
1,4-naphthoquinone + a reduced electron donor + oxygen → an oxidized electron donor + juglone + H2O
histamine + NADPH + oxygen → H2O + N-hydroxyhistamine + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 3-hexaprenyl-4-aminobenzoate + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 3-hexaprenyl-4-amino-5-hydroxybenzoate
NADPH + 20-deoxo-20-dihydrorosamicin + H+ + oxygen → H2O + 20-dihydrorosamicin + NADP+
NADPH + H+ + 3-geranylgeranylindole + oxygen → H2O + NADP+ + 10,11-epoxy-3-geranylgeranylindole
a reduced electron donor + oxygen + β-carotene → an oxidized electron donor + isocryptoxanthin + H2O
4,5-seco-dopa → H2O + H+ + betalamate
a reduced electron donor + cadaverine + oxygen → an oxidized electron donor + H2O + N-hydroxycadaverine + H+
hydroxyacetone + NADPH + oxygen → acetate + H2O + formaldehyde + NADP+
a reduced electron donor + H+ + 2-hydroxylamino-4,6-dinitrotoluene → an oxidized electron donor + H2O + 2-amino-4,6-dinitrotoluene
2-amino-5-oxohexanoate → H2O + H+ + 1-pyrroline-2-methyl-5-carboxylate
2 H+ + oxygen + coproporphyrinogen III → 2 H2O + 2 CO2 + protoporphyrinogen IX
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-18:2-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:2-2-18:3-monogalactosyldiacylglycerol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + pentalen-13-ol → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + pentalen-13-al
4β-hydroxymethyl-4α-methyl-5α-cholesta-8,24-dien-3β-ol + NADH + H+ + oxygen → 2 H2O + 4β-formyl-4α-methyl-5α-cholesta-8,24-dien-3β-ol + NAD+
3 ATP + anthranilate + L-tryptophan + L-alanine → 2 H+ + 3 diphosphate + 3 AMP + H2O + fumiquinazoline F
L-valyl-L-arginyl-4-hydroxy-5-phosphonopentanoate → H2O + rhizocticin B
NADPH + 2,3',4,6-tetrahydroxybenzophenone + oxygen → 2 H2O + 1,3,7-trihydroxyxanthone + NADP+
quinolin-2-ol + NADH + H+ + oxygen → H2O + quinolin-2,8-diol + NAD+
NADPH + H+ + oxygen + 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester → 2 H2O + NADP+ + 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester
NADH + H+ + oxygen + 2-hydroxyastaxanthin → H2O + NAD+ + 2,3,2',3'-tetrahydroxy-β,β-carotene-4,4'-dione
NADH + H+ + oxygen + adonixanthin → H2O + NAD+ + 2-hydroxyadonixanthin
5-epi-valiolone → H2O + valienone
(1S)-bornane-2,5-dione + NADH + H+ + oxygen → H2O + (-)-5-oxo-1,2-campholide + NAD+
2 hydrogen peroxide + isoliquiritigenin → 2 H2O + 2-[hydroperoxy(4-hydroxyphenyl)methyl]-6-hydroxy-1-benzofuran-3-one
2 a reduced electron donor + 2 oxygen + 7,8-dihydro-neoxanthin → 2 an oxidized electron donor + 3 H2O + fucoxanthinol
2,6,7,4'-tetrahydroxyisoflavanone → H2O + 6,7,4'-trihydroxyisoflavone
oleate + NADPH + H+ + oxygen → H2O + NADP+ + 18-hydroxyoleate
3 oxygen + 5 H+ + 6 a reduced ferredoxin [iron-sulfur] cluster + lanosterol → 4 H2O + 6 an oxidized ferredoxin [iron-sulfur] cluster + 4,4-dimethyl-5-α-cholesta-8,14,24-trien-3-β-ol + formate
4,4-dimethyl-5α-cholesta-8-en-3β-ol + NADH + H+ + oxygen → 4β-hydroxymethyl-4α-methyl-5α-cholesta-8-en-3β-ol + H2O + NAD+
(1R,4S)-1-hydroxymenth-8-en-2-one + NADPH + H+ + oxygen → (4S)-7-hydroxy-4-isoprenyl-7-methyl-2-oxo-oxepanone + H2O + NADP+
2-oxo-3-(phosphooxy)propyl 8-methyl-3-oxodecanoate → H2O + [4-(6-methyloctanoyl)-5-oxo-2H-furan-3-yl]methyl phosphate
24-epi-campesterol + NADPH + H+ + oxygen → 2 H2O + brassicasterol + NADP+
(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate + a reduced electron donor + oxygen → an oxidized electron donor + 18R-hydroxy-icosapentaenoate + H2O
plectaniaxanthin + NAD(P)H + H+ + oxygen → myxol + H2O + NAD(P)+
NAD(P)H + lathosterol + H+ + oxygen → 2 H2O + 7-dehydrocholesterol + NAD(P)+
NADPH + 4-(methylsulfanyl)butyl-glucosinolate + H+ + oxygen → H2O + NADP+ + glucoraphanin
2 inosine + oxygen → 2 H2O + 2 5'-dehydroinosine
a reduced electron donor + 2-chloro-N-(2,6-diethylphenyl)-N-hydroxymethylacetamide → an oxidized electron donor + H2O + 2-chloro-N-(2,6-diethylphenyl)-N-methylacetamide
H+ + oxygen + 6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol → H2O + 3-demethylubiquinol-10
NADPH + L-tryptophan + oxygen → H2O + N2-hydroxy-L-tryptophan + NADP+
NADPH + H+ + oxygen + 8-O-methylfusarubinaldehyde → H2O + NADP+ + 8-O-methyl-5-hydroxy-fusarubinaldehyde
5-methyl-1-naphthoate + NADPH + H+ + oxygen → 3-hydroxy-5-methyl-1-naphthoate + H2O + NADP+
15-oxo spinosyn macrolactone → H2O + 11-dehydro-15-oxo spinosyn macrolactone
L-tryptophan + oxygen → H2O + (indol-3-yl)acetamide + CO2
4-hydroxylaminobenzoate + oxygen → H2O + 4-nitrobenzoate
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + cyclo-(L-tyrosyl-L-tyrosyl) + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + mycocyclosin
N,N-dihydroxy-L-dihomomethionine + H+ → H2O + (E)-5-(methylsulfanyl)pentanal oxime + CO2
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + β-carotene → 2 an oxidized ferredoxin [iron-sulfur] cluster + β-cryptoxanthin + H2O
3-hydroxypropanal → H2O + acrolein
oxygen + dihydrosorgoleone → H2O + H+ + sorgoleone
2 H+ + 4 a reduced electron donor + 4 oxygen + protoheme → 4 an oxidized electron donor + 4 H2O + Fe2+ + β-staphylobilin + carbon monoxide
N,N-dihydroxy-L-phenylalanine + H+ → H2O + (E)-phenylacetaldehyde oxime + CO2
abietatriene + NADPH + H+ + oxygen → H2O + NADP+ + dehydroabietadienol
2 a reduced electron donor + 2 oxygen + echinenone → 2 an oxidized electron donor + 3 H2O + canthaxanthin
5,5'-dehydrodivanillate + NADH + H+ + oxygen → 2,2',3-trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl + H2O + formaldehyde + NAD+
H2O + NAD+ + D-octopine ← NADH + pyruvate + H+ + L-arginine
bupropion + NADPH + H+ + oxygen → H2O + hydroxybupropion + NADP+
colanic acid + core oligosaccharide-lipid A (E. coli K-12 core type) → H2O + MLPS
(2Z,4Z)-2-amino-5-formylhexa-2,4-dienedioate → 2,5-pyridinedicarboxylate + H2O
D-erythro-imidazole-glycerol-phosphate → H2O + imidazole acetol-phosphate
5-S-cysteinyldopaquinone → 7-[(2S)-2-amino-2-carboxylatoethyl]-5-hydroxy-2H-1,4-benzothiazine-3-carboxylate + H2O + H+
L-tyrosine + oxygen → dopaquinone + H2O
2 L-glutamate + (4-{4-[2-(γ-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine → 2 H2O + methanofuran b
NADPH + H+ + (2E,6E)-farnesoate + oxygen → H2O + juvenile hormone III acid + NADP+
isotrichodiol → H2O + 12,13-epoxytrichothec-9-ene
2 FADH2 + 2,6-dichlorohydroquinone + oxygen → 2 FAD + 2 H+ + H2O + 6-chlorohydroxyquinol + chloride
NADPH + H+ + 3-octaprenyl-4-hydroxybenzoate + oxygen → 3,4-dihydroxy-5-all-trans-octaprenylbenzoate + H2O + NADP+
progesterone + NADPH + H+ + oxygen → H2O + testosterone acetate + NADP+
L-aspartate 4-semialdehyde + pyruvate → 2 H2O + (S)-2,3-dihydrodipicolinate + H+
a reduced electron donor + linoleate + oxygen → 2 H2O + an oxidized electron donor + α-linolenate
7-methylxanthine + NAD(P)H + H+ + oxygen → xanthine + H2O + NAD(P)+ + formaldehyde
L-ascorbate + oxygen → 2 H2O + monodehydroascorbate radical
a reduced electron donor + simazine + oxygen → an oxidized electron donor + H2O + deethylsimazine + acetaldehyde
NADPH + H+ + (4S)-limonene + oxygen → H2O + NADP+ + (-)-cis-carveol
NADH + H+ + dimethyl sulfide + oxygen → H2O + dimethyl sulfoxide + NAD+
H2O + NADP+ + carboxyspermidine ← L-aspartate 4-semialdehyde + NADPH + putrescine + H+
2 a reduced electron donor + perchlorate → 2 an oxidized electron donor + 2 H2O + H+ + chlorite
NADH + 3β-hydroxy-4α-methyl-5α-cholest-7-ene-4β-carbaldehyde + oxygen → H2O + NAD+ + 3β-hydroxy-4α-methyl-5α-cholest-7-ene-4β-carboxylate
4α-formyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen → H2O + NAD(P)+ + 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol
a reduced electron donor + oxygen + 4'-hydroxyadonixanthin → an oxidized electron donor + H2O + 4',4'-dihydroxyadonixanthin
2 H+ + NADPH + emodin → H2O + NADP+ + chrysophanol
NADH + urate + H+ + oxygen → H2O + (S)-5-hydroxyisourate + NAD+
2 NADH + 2 H+ + 2 oxygen + β-carotene → 2 H2O + 2 NAD+ + (2R,2'R)-dihydroxy-all-trans-β-carotene
3 oxygen + 4 2-aminophenol → 2 isophenoxazine + 6 H2O
FADH2 + L-tryptophan + chloride + oxygen → 2 H2O + FAD + 5-chloro-L-tryptophan
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-α-linolenoyl-2-palmitoyl-phosphatidylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-α-linolenoyl-2-(3E)-hexadecenoyl-phosphatidylglycerol
a reduced electron donor + toluene + oxygen → an oxidized electron donor + H2O + 4-methylphenol
NADPH + oxygen + 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester → 2 H2O + NADP+ + 3,8-divinyl protochlorophyllide a
NAD(P)H + 4-hydroxyacetophenone + oxygen → H2O + (4-hydroxyphenyl)acetate + NAD(P)+
NADPH + H+ + 2-nonaprenylphenol + oxygen → H2O + NADP+ + 3-(all-trans-nonaprenyl)benzene-1,2-diol
NADPH + 7,2,2'-trihydroxy-4',5'-methylenedioxyisoflav-3-ene + H+ + oxygen → H2O + NADP+ + (3R,4R)-7,2,4,2'-tetrahydroxy-4',5'-methylenedioxyisoflav-3-ene
hydrogen peroxide + 1-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol → H2O + veratraldehyde + glycolaldehyde + guaiacol
NADPH + H+ + oxygen + 12a-deshydroxy-desmethylanthrotainin → H2O + NADP+ + desmethylanthrotainin
NADPH + oxygen + calcidiol → H2O + calcitriol + NADP+
2 menadiol + oxygen → 2 menadione + 2 H2O
a reduced electron donor + oxygen + 3,4'-dihydroxyechinenone → an oxidized electron donor + H2O + 3,4',4'-trihydroxyechinenone
2 Mn2+ + 2 H+ + hydrogen peroxide → 2 H2O + 2 Mn+3
ferribactin + NADP+ + oxygen → pyoverdine I + H2O + NADPH + H+
4,4-dihydroxy-β,β-carotene → H2O + echinenone
N,N-dihydroxy-L-valine + H+ → H2O + (E)-2-methylpropanal-oxime + CO2
NADH + H+ + styrene + oxygen → H2O + NAD+ + (R)-2-phenyloxirane
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + L-aspartate 4-semialdehyde + hydrogen sulfide → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + L-homocysteine
a reduced electron donor + benzyl-6-hydroxy-2-cyclohexene-on-oyl + oxygen → an oxidized electron donor + H2O + salicyl-6-hydroxy-2-cyclohexene-on-oyl
H2O + L-saccharopine + NADP+ ← (S)-2-amino-6-oxohexanoate + NADPH + H+ + L-glutamate
2 methanesulfenate → H2O + dimethyl thiosulfinate
2-oxoglutarate + oxygen + (2R,3S,4S)-leucopelargonidin → 2 H+ + H2O + (4S)-2,3-dehydroleucopelargonidin + succinate + CO2
2,4',7-trihydroxyisoflavanone → H2O + daidzein
dimethyl sulfoxide + menaquinol-8 + H+ → H2O + menaquinone-8 + dimethyl sulfide
hydrogen peroxide + 6-amino-2-oxohexanoate → H2O + 5-aminopentanoate + CO2
NADH + H+ + 2-methylphenol + oxygen → H2O + 3-methylcatechol + NAD+
NADPH + O-aminobenzaldehyde + H+ + oxygen → 2 H2O + anthranil + NADP+
NADPH + palustradienal + oxygen → H2O + NADP+ + palustric acid
3 NADPH + 5 malonyl-CoA + 8 H+ + acetyl-CoA + oxygen → 3 NADP+ + 4 H2O + 6 coenzyme A + 6 CO2 + 1,8-dihydroxy-3-methylnaphthalene
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-16:2-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-16:2-monogalactosyldiacylglycerol
NADPH + H+ + oxygen + (+)-epi-isozizaene → H2O + (5S)-albaflavenol + NADP+
hydrogen peroxide + NADPH + H+ → 2 H2O + NADP+
hydrogen peroxide + NADH + H+ → 2 H2O + NAD+
NAD(P)H + theobromine + H+ + oxygen → 7-methylxanthine + H2O + NAD(P)+ + formaldehyde
2 H+ + NADPH + oxygen + senecionine → H2O + NADP+ + senecionine N-oxide
D-galactonate → H2O + 2-dehydro-3-deoxy-D-galactonate
7-oxoheptanoate + a reduced electron donor + hydrogen sulfide → an oxidized electron donor + H2O + 7-mercaptoheptanoate
NADPH + (-)-dihydrocarvone + H+ + oxygen → H2O + NADP+ + (3S,6S)-6-isopropenyl-3-methyloxepan-2-one
2 H+ + hexahydroxydiphenic acid → 2 H2O + ellagic acid
1-phenyl-3-(3-C-glucosyl-2,4,6-trihydroxyphenyl)propane-1,3-dione → H2O + 6-C-glucosyl chrysin + H+
trichotriol → 2 H2O + isotrichodermol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:3-2-16:1-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-16:2-monogalactosyldiacylglycerol
caloxanthin + NADH + H+ + oxygen → nostoxanthin + H2O + NAD+
4-sulfoacetophenone + NADPH + H+ + oxygen → H2O + 4-sulfophenyl acetate + NADP+
NADPH + glucoiberverin + H+ + oxygen → H2O + NADP+ + glucoiberin
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + pentalenene → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + pentalen-13-ol
NADPH + tert-butyl alcohol + H+ + oxygen → H2O + 2-methylpropane-1,2-diol + NADP+
(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate → H2O + 2-succinylbenzoate
NADH + precorrin-3A + H+ + oxygen → H2O + precorrin-3B + NAD+
2 H+ + 2 sulochrin + oxygen → 2 H2O + 2 (-)-bisdechlorogeodin
NADH + H+ + oxygen + canthaxanthin → H2O + NAD+ + 2-hydroxycanthaxanthin
glycine + 3-chlorobenzoate → H2O + m-chlorohippurate
phenol + NADH + H+ + oxygen → H2O + hydroquinone + NAD+
12 H+ + 6 NADPH + 6 (S)-methylmalonyl-CoA + propanoyl-CoA → 6 NADP+ + 6 CO2 + 7 coenzyme A + H2O + 6-deoxyerythronolide B
FADH2 + phenol + oxygen → FAD + H2O + catechol + H+
versiconal → H2O + versicolorin B
4α-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + H+ + oxygen → 4α-hydroxymethyl-5α-cholesta-8,24-dien-3β-ol + H2O + NAD(P)+
a reduced ferredoxin [iron-sulfur] cluster + oxygen + corticosterone → an oxidized ferredoxin [iron-sulfur] cluster + H2O + 18-hydroxycorticosterone
a reduced electron donor + atrazine + oxygen → an oxidized electron donor + H2O + deethylsimazine + acetone
2 FMNH2 + 2 oxygen + dimethyl sulfone → 2 FMN + 2 H2O + 3 H+ + formaldehyde + methanesulfonate
2 NADPH + 2 H+ + 2 oxygen + tetracenomycin B2 → 2 NADP+ + H2O + 8-demethyltetracenomycin C
NADPH + 7-deoxyloganetin + H+ + oxygen → H2O + loganetin + NADP+
NADPH + H+ + oxygen + tigecycline → H2O + NADP+ + 11-hydroxytigecycline
hydrogen peroxide + indole → H2O + indolin-2-one
2 H+ + 3 NAD(P)H + 3 oxygen + 4α-methyl-5α-cholesta-8-en-3-ol → 3 NAD(P)+ + 4 H2O + 4α-carboxy-5α-cholesta-8-en-3β-ol
NADPH + lyngbyatoxin A + H+ + oxygen → H2O + lyngbyatoxin C + NADP+
2 N5-formyl-N5-hydroxy-L-ornithine + 2 L-threonine + 2 L-serine + L-tyrosine + L-lysine + L-glutamate + L-2,4-diaminobutanoate + L-arginine → 12 H2O + ferribactin + H+
2 a reduced electron donor + 3'-phospho-JI-20A → 2 an oxidized electron donor + H2O + phosphate + gentamicin C1a
2 H+ + 3 a reduced electron donor + 3 oxygen + protoheme → 3 an oxidized electron donor + 3 H2O + Fe2+ + mycobilin b
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 2,4-dibromophenol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 2,6-dibromo-4-(2,4-dibromophenoxy)phenol
scyllo-inosose → 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione + H2O
NADPH + acetone + H+ + oxygen → H2O + methyl acetate + NADP+
β-cryptoxanthin + NADH + H+ + oxygen → zeaxanthin + H2O + NAD+
kauralexin A1 + oxygen → H2O + kauralexin A3
13(S)-HPOTE → etherolenate + H2O
H+ + oxygen + 6-methoxy-3-methyl-2-all-trans-heptaprenyl-1,4-benzoquinol → H2O + 3-demethylubiquinol-7
2 a reduced ferredoxin [iron-sulfur] cluster + H+ + oxygen + 2,4-dibromophenol + 2,3,4-tribromo-1H-pyrrole → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + pentabromopseudilin
NADPH + H+ + (-)-phaseollidin + oxygen → 2 H2O + NADP+ + (-)-phaseollin
2-oxoglutarate + H+ + chloride + oxygen + ambiguine H → H2O + succinate + ambiguine A + CO2
1-O-alkyl-sn-glycerol + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + oxygen → H2O + L-erythro-7,8-dihydrobiopterin + 1-(1-hydroxyalkyl)-sn-glycerol
ent-isokaurene + NADPH + H+ + oxygen → H2O + kauralexin B1 + NADP+
4',4'-dihydroxy-4,4'-diapolycopen-4-al → 4,4'-diapolycopen-4,4'-dial + H2O
NADH + H+ + oxygen + 3-hydroxy-4-methyl-benzoate → H2O + 4-methylgentisate + NAD+
2 H+ + NAD(P)H + oxygen + 4-aminobenzoate → H2O + 4-aminophenol + NAD(P)+ + CO2
N, N-dihydroxytrihomomethionine + H+ → H2O + (E)-6-(methylsulfanyl)hexanal oxime + CO2
L-arogenate + H+ → H2O + L-phenylalanine + CO2
24,25-dihydrolanosterol + NADPH + H+ + oxygen → 4,4-dimethyl-14α-hydroxymethyl-5α-cholesta-8-en-3β-ol + H2O + NADP+
isopimaradiene-diol → H2O + isopimara-7,15-dienal
gallate + oxygen → H2O + 2-pyrone-4,6-dicarboxylate + H+
H2O + n-butyronitrile ← butyramide
(R)-synephrine → H2O + 4-[(E)-2-(methylamino)ethenyl]phenol
2 3-amino-4-hydroxybenzaldehyde + 2 oxygen + N-acetyl-L-cysteine → 3 H2O + formate + H+ + grixazone A
(+)-dihydrokaempferol + 2-oxoglutarate + oxygen → H2O + H+ + succinate + CO2 + kaempferol
FADH2 + (4-hydroxyphenyl)acetate + oxygen → FAD + H2O + 3,4-dihydroxyphenylacetate + H+
NAD(P)H + H+ + preaspyridone A + oxygen → H2O + NAD(P)+ + 14-hydroxypreaspyridone A
2-oxoglutarate + L-arginine + oxygen → H2O + guanidinium + H+ + (S)-1-pyrroline-5-carboxylate + succinate + CO2
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + myxocoxanthin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + plectaniaxanthin + H2O
UDP-α-D-glucose → H2O + UDP-4-dehydro-6-deoxy-α-D-glucose
3-C-glucosyl-2,4,4',6-tetrahydroxydibenzoylmethane → H2O + isovitexin
H2O + yersinopine + NADP+ ← (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + NADPH + pyruvate + H+
dimethylamine + NADPH + H+ + oxygen → H2O + methylamine + formaldehyde + NADP+
formate + H+ + GTP → H2O + dGTP + CO2
2 3-[(8Z,11E,13Z)-pentadeca-8,11,13-trien-1-yl] )catechol + a reduced electron donor + oxygen → 2 H2O + an oxidized electron donor + 8'-(3,4-dihydroxy-5-alkenyl)phenyl-3-[9'E,11'E,13'Z-pentadecatrienyl]catechol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1,3-dimethylbenzene + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 3-methylbenzyl alcohol
myxocoxanthin + a reduced electron donor + oxygen → an oxidized electron donor + hydroxydeoxyflexixanthin + H2O
hydrogen peroxide + oleate + H+ → 2 H2O + 1E,8Z-heptadecadiene + CO2
(3S,5S)-carbapenam-3-carboxylate + 2-oxoglutarate + oxygen → (5R)-carbapen-2-em-3-carboxylate + H2O + succinate + CO2
NADPH + H+ + oxygen + 3,7,4'-trimethylquercetin → H2O + NADP+ + 2'-hydroxy 3,7,4'-trimethylquercetin
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:3-2-18:2-digalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-18:3-digalactosyldiacylglycerol
(2S)-4-acetamido-2-aminobutanoate → H2O + ectoine
GDP-D-glycero-α-D-manno-heptose → GDP-6-deoxy-4-keto-D-lyxo-heptose + H2O
penicillin N + 2-oxoglutarate + oxygen → deacetoxycephalosporin C + H2O + succinate + CO2
NADPH + L-kynurenine + H+ + oxygen → 3-hydroxy-L-kynurenine + H2O + NADP+
(R)-lactoyl-CoA → H2O + acryloyl-CoA
a reduced electron donor + (3R,4S)-tetrahydrodaidzein → an oxidized electron donor + H2O + (S)-equol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + narbomycin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + neopikromycin
9(S)-HPOTE → colnelenate + H2O
NADPH + 20-hydroxy-5-O-mycaminosyltylactone + oxygen → 2 H2O + 20-oxo-5-O-β-mycaminosyltylactone + NADP+
4α-formyl-4β-methyl-5α-cholesta-8-en-3β-ol + NAD(P)H + oxygen → H2O + NAD(P)+ + 4α-carboxy-4β-methyl-5α-cholesta-8-en-3β-ol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 30-hydroxylanosterol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 30-oxolanosterol
2 L-serine + 3 methylglutaconyl hydroxy ornithine + 3 ATP + glycine + Fe3+ → 3 H2O + 3 H+ + 3 diphosphate + 3 AMP + ferrichrome A
NADPH + stipitalide + H+ + oxygen → H2O + stipitaldehydate + NADP+
E-pyridine-3-aldoxime → H2O + 3-cyanopyridine
7,8-dihydrolumazine + 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one → H2O + aurodrosopterin
2',2'-dihydroxy-2-oxospirilloxanthin → H2O + 2,2'-dioxospirilloxanthin
H+ + 8α-hydroxy-germacra-1(10),4,11(13)-trien-12-oate → H2O + 8-epi-inunolide
β-cembratriene-ol + NAD(P)H + H+ + oxygen → β-cembratriene-4,6-diol + H2O + NAD(P)+
H+ + oxygen + protodeoxyviolaceinate → H2O + CO2 + prodeoxyviolacein
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 20-oxo-5-O-β-mycaminosyltylactone + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 5-O-β-mycaminosyltylonolide
2 hydrogen peroxide + melatonin → 2 H2O + N1-acetyl-N2-formyl-5-methoxykynuramine
diatoxanthin + NADPH + H+ + oxygen → diadinoxanthin + H2O + NADP+
2 L-arginine + 3 NADPH + 4 oxygen + H+ → 2 L-citrulline + 2 nitric oxide + 3 NADP+ + 4 H2O
2 Nω-hydroxy-L-arginine + 2 oxygen + NADPH → 2 H2O + 2 L-citrulline + 2 nitric oxide + NADP+ + H+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 10-deoxymethymycin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + methymycin
N-methyl-N-[(2S)-1-phenylpropan-2-yl]hydroxylamine + NADPH + H+ + oxygen → 2 H2O + (Z)-methyl(oxido)(1-phenylpropan-2-ylidene)azanium + NADP+
2-amino-4-hydroxy-5-phosphonopentanoate → H2O + L-2-amino-5-phosphono-3-cis-pentenoate
a reduced electron donor + oxygen + gibberellin A20 → 2 H2O + an oxidized electron donor + gibberellin A5
NADPH + (22R)-hydroxycholesterol + H+ + oxygen → H2O + NADP+ + 22,26-dihydroxycholesterol
NADPH + H+ + oxygen + 1-deoxy-11-oxopentalenate → H2O + NADP+ + pentalenolactone D
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:1-2-16:1-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:1-2-16:2-monogalactosyldiacylglycerol
L-arabinonate → H2O + 2-dehydro-3-deoxy-L-arabinonate
hydrogen peroxide + L-methionine → H2O + L-methionine-(R)-S-oxide
a reduced electron donor + oxygen + adonixanthin → 2 H+ + an oxidized electron donor + H2O + (3S,3'S)-astaxanthin
2 hydroxyl radical + adenine → H2O + isoguanine
NADH + 3-hydroxy-trans-cinnamate + H+ + oxygen → H2O + 2,3-dihydroxy-trans-cinnamate + NAD+
H2O + MMF1 butenolide intermediate → H2O + methylenomycin furan 1
2 NADPH + 2 H+ + 2 oxygen + tetracenomycin A2 → 2 NADP+ + H2O + tetracenomycin C
2 H+ + 3 NADPH + 3 oxygen + 5β-cholestane-3α,7α-diol → 3 NADP+ + 4 H2O + (25R)-3α,7α-dihydroxy-5-β-cholestanate
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 6-deoxyerythronolide B + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + erythronolide B
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + 2-oxospirilloxanthin → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 2'-hydroxy-2-oxospirilloxanthin
NADPH + H+ + 7α-hydroxycholest-4-en-3-one + oxygen → H2O + NADP+ + 7α,12α-dihydroxycholest-4-en-3-one
NADPH + H+ + bromide + oxygen + 2,4-dibromophenol → 2 H2O + NADP+ + 2,4,6-tribromophenol
4,4-dihydroxy-4,4'-diapolycopene → 4,4'-diapolycopene-4-al + H2O
NADPH + H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + oxygen → H2O + 2-methoxy-6-all trans-octaprenyl-1,4-benzoquinol + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + acetochlor + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + ethyl formate + 2-chloro-N-(2-ethyl,6-methylphenyl)acetamide
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-18:2-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-18:2-monogalactosyldiacylglycerol
2 oxygen + NAD(P)H + H+ + aminopyrrolnitrin → 2 H2O + pyrrolnitrin + NAD(P)+
FMNH2 + oxygen + nitrilotriacetate → FMN + H2O + glyoxylate + iminodiacetate
NADPH + H+ + oxygen + benzoate → H2O + NADP+ + 4-hydroxybenzoate
2 H+ + salicylate + NADH + oxygen → H2O + catechol + NAD+ + CO2
2 a reduced ferredoxin [iron-sulfur] cluster + (25R)-26-oxocholesterol + H+ + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + (25R)-3β-hydroxycholest-5-en-26-oate + H2O
(3R)-hydroxy-auricoloyl-CoA → H2O + (2E,11Z,17Z)-14R-hydroxy-icosa-11,17-trienoyl-CoA
preuroporphyrinogen → H2O + uroporphyrinogen-I
8-hydroxy-trans-neoxanthin + a reduced electron donor + oxygen → an oxidized electron donor + 8,8-dihydroxy-trans-neoxanthin + H2O
α-D-sedoheptulopyranose 7-phosphate → H2O + (R)-demethyl-4-deoxygadusol + phosphate
H+ + oxygen + α-hydroxyheme → H2O + verdoheme + carbon monoxide
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + isocryptoxanthin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + isozeaxanthin + H2O
FADH2 + styrene + oxygen → FAD + H2O + H+ + (S)-2-phenyloxirane
2 H+ + 3 a reduced electron donor + 3 oxygen + protoheme → 3 an oxidized electron donor + 3 H2O + Fe2+ + mycobilin a
2 isoniazid + hydrogen peroxide → 2 H2O + 2 diazene + 2 isonicotinate acyl radical
H2O + MMF4 butenolide intermediate → H2O + methylenomycin furan 4
hydrogen peroxide + stearate + H+ → 2 H2O + 1-heptadecene + CO2
NADPH + aurachin D + H+ + oxygen → H2O + aurachin C + NADP+
2 NADPH + 2 oxygen + dTDP-β-L-evernosamine + H+ → 2 NADP+ + 3 H2O + dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-β-L-arabino-hexopyranose
14 NADPH + 22 H+ + 9 malonyl-CoA + acetyl-CoA → 10 coenzyme A + 14 NADP+ + 8 H2O + 9 CO2 + arachidonate
2 hydroxyl radical + dATP → 2-hydroxy-dATP + H2O
3-hydroxyphenylacetate + NAD(P)H + H+ + oxygen → H2O + homogentisate + NAD(P)+
19-oxoandrost-4-ene-3,17-dione + oxygen → H2O + estrone + CO2
phenol + NADPH + H+ + oxygen → H2O + catechol + NADP+
pregna-4,9(11)-diene-3,20-dione + a reduced electron donor + oxygen → an oxidized electron donor + 9,11-α-epoxypregn-4-ene-3,20-dione + H2O
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + spheroidene + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + spheroiden-2-ol + H2O
5-methyl-N-(4-nitrophenyl)-1-oxo-1λ4-thiophene-2-carboxamide + NADPH + H+ + oxygen → H2O + 5-methyl-N-(4-nitrophenyl)-1,1-dioxo-1λ6-thiophene-2-carboxamide + NADP+
6-[3-hydroxy-2-(3,5,7-trioxononanoyl)phenyl]-3,5-dioxohexanoate → 2 H2O + 12-deoxyaklanoate
ubiquinol-10 + nitrate → H2O + ubiquinone-10 + nitrite
4-(1-methyl-5-hydroxy-2-pyrrolidinyl)-3-oxobutanoate methyl ester → H2O + methyl ecgonone + H+
1-(3-aminopropyl)-4-aminobutanal → H2O + 1-(3-aminopropyl)-pyrrolinium
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanine + ammonium → H2O + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + neomethymycin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + novamethymycin
γ-butyrobetaine + NAD(P)H + H+ + oxygen → H2O + succinate semialdehyde + NAD(P)+ + trimethylamine
NAD(P)H + H+ + pretenellin A + oxygen → 2 H2O + NAD(P)+ + pretenellin B
NADPH + H+ + (-)-menthone + oxygen → H2O + NADP+ + (4R,7S)-7-isopropyl-4-methyloxepan-2-one
an oxidized electron donor + H2O + nitrous oxide ← 2 nitric oxide + a reduced electron donor
prephenate + S-adenosyl-L-methionine → H2O + S-adenosyl-S-carboxymethyl-L-homocystein + 3-phenyl-2-oxopropanoate
3 oxygen + 5 H+ + 6 a reduced ferredoxin [iron-sulfur] cluster + candicinolide → 4 H2O + 6 an oxidized ferredoxin [iron-sulfur] cluster + 18-carboxy candicinolide
2 NAD(P)H + 2 H+ + 4-nitrobenzoate → 2 NAD(P)+ + H2O + 4-hydroxylaminobenzoate
(25R)-26-hydroxycholesterol + NADPH + H+ + oxygen → (25R)-7α,26-dihydroxycholesterol + H2O + NADP+
(3R,9Z,12Z,15Z,18Z)-3-hydroxytetracosatetraenoyl-CoA → H2O + (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA
NADPH + H+ + oxygen + pentalen-13-ol → 2 H2O + NADP+ + pentalen-13-al
7,8-dihydropterin + 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one → H2O + drosopterin
2 H+ + deoxyhumulone + oxygen → H2O + humulone
4-hydroxybutanoyl-CoA → H2O + crotonyl-CoA
dimethyl sulfoxide + NADH + H+ + oxygen → H2O + dimethyl sulfone + NAD+
6 L-glutamate + (4-{4-[2-(γ-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine → 6 H2O + methanofuran d
NADPH + tert-amyl alcohol + H+ + oxygen → 2 H2O + NADP+ + isoprenyl alcohol
NADPH + (-)-matairesinol + H+ + oxygen → H2O + (-)-thujaplicatin + NADP+
NADH + butan-2-one + H+ + oxygen → H2O + NAD+ + ethyl acetate
a reduced electron donor + H+ + L-tryptophan + oxygen → an oxidized electron donor + H2O + ammonium + (indol-3-yl)acetaldehyde + CO2
formaldehyde + 5,6,7,8-tetrahydrofolate → H2O + 5,10-methylenetetrahydropteroyl mono-L-glutamate
NADPH + H+ + 16-hydroxypalmitoyl-CoA + oxygen → 10,16-dihydroxypalmitoyl-CoA + H2O + NADP+
androst-4-ene-3,17-dione + oxygen → H2O + 19-hydroxyandrost-4-ene-3,17-dione
N2-hydroxy-L-tryptophan + NADPH + H+ + oxygen → H2O + N2,N2-dihydroxy-L-tryptophan + NADP+
orcinol + NADH + H+ + oxygen → H2O + NAD+ + 2,3,5-trihydroxytoluene
7 H+ + 8 malonyl-CoA → 8 coenzyme A + 8 CO2 + H2O + octoketide
NADPH + H+ + (4R)-limonene + oxygen → H2O + NADP+ + (+)-trans-carveol
NADH + O-aminobenzaldehyde + oxygen → anthranilate + H2O + NAD+
an oxidized electron donor + N-[(3R)-6-(5,6-dihydropyridin-2-yl)-7-hydroxy-8-[(2E)-1-hydroxybut-2-en-1-yl]-2-oxo-1,5-oxathiocan-3-yl]acetamide → H2O + N-[(3R)-8-[(2E)-but-2-enoyl]-6-(5,6-dihydropyridin-2-yl)-2-oxo-4,8-dihydro-3H-1,5-oxathiocin-3-yl]acetamide + a reduced electron donor
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-oleoyl-2-palmitoyl-phosphatidylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-linoleoyl-2-palmitoyl-phosphatidylglycerol
GDP-4-dehydro-α-D-rhamnose + L-glutamate → H2O + 2-oxoglutarate + H+ + 2-GDP-[(2S,3S,6R)-5-amino-6-methyl-3,6-dihydro-2H-pyran-3-ol]
2 H+ + 3 NADPH + 3 oxygen + 24,25-dihydrolanosterol → 3 NADP+ + 4 H2O + 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + formate
a reduced electron donor + 2-methoxy-6-(all-trans-nonaprenyl)phenol + oxygen → an oxidized electron donor + H2O + 2-methoxy-6-all trans-nonaprenyl-1,4-benzoquinol
5 H+ + 5 malonyl-CoA → 5 coenzyme A + 5 CO2 + H2O + 5,7-dihydroxy-2-methylchromone
NADPH + avenasterol + H+ + oxygen → 2 H2O + 5-dehydroavenasterol + NADP+
NADPH + H+ + oxygen + 13-deoxydaunorubicin → H2O + NADP+ + 13-dihydrodaunorubicin
phenol + phosphate → H2O + phenyl phosphate
3 an oxidized ferredoxin [iron-sulfur] cluster + 3 H2O + hydrogen sulfide ← 3 a reduced ferredoxin [iron-sulfur] cluster + 8 H+ + sulfite
a reduced electron donor + (+)-sesamin + oxygen → an oxidized electron donor + H2O + (+)-sesaminol
2 nitroxyl → H2O + nitrous oxide
2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + prenyl diphosphate ← 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate
H2O + NADP+ + (+)-catechin ← NADPH + H+ + (2R,3S,4S)-leucocyanidin
2 H+ + 2 sulochrin + oxygen → 2 H2O + 2 (+)-bisdechlorogeodin
cis-indole-2,3-dihydrodiol → H2O + indoxyl
2',3,4,4',6'-pentahydroxychalcone 4'-O-β-D-glucoside + oxygen → H2O + bracteatin 6-O-glucoside
dopamine + protoemetine → H2O + 7'-O-demethylcephaeline
1,1-dihydroxypropan-2-one → H2O + methylglyoxal
NADH + 4,4-dimethyl-5α-cholest-7-en-3β-ol + H+ + oxygen → H2O + NAD+ + 4β-hydroxymethyl-4α-methyl-5α-cholest-7-en-3β-ol
2-(3-{3-[(1E)-prop-1-en-1-yl]oxiran-2-yl}oxiran-2-yl)-5,6-dihydro-1H-pyridin-2-ol → H2O + 2-(3-{3-[(1E)-prop-1-en-1-yl]oxiran-2-yl}oxiran-2-yl)-5,6-dihydropyridine
NADPH + H+ + (+)-camphor + oxygen → (+)-6-exo-hydroxycamphor + H2O + NADP+
NADPH + H+ + 2-methyl-4-chlorophenol + oxygen → H2O + NADP+ + 5-chloro-3-methylcatechol
2 dopaxanthin + oxygen → 2 H2O + 2 dopaxanthin quinone
NADH + H+ + oxygen + 3-hydroxybenzoate → H2O + gentisate + NAD+
2 NADH + 2 oxygen + 4 H+ + chromopyrrolate → 2 NAD+ + 2 CO2 + 3 H2O + K-252c
2 NADPH + behenate + oxygen → 2 NADP+ + H2O + 22-hydroxydocosanoate
oleate + ethanol + H+ → H2O + ethyl oleate
N2,N2-dihydroxy-L-tryptophan + H+ → H2O + (E)-(indol-3-yl)acetaldehyde oxime + CO2
L-carnitine + NAD(P)H + H+ + oxygen → H2O + NAD(P)+ + L-malic semialdehyde + trimethylamine
ferribactin + oxygen → pyoverdine I + H2O
2-oxoglutarate + H+ + chloride + oxygen + ambiguine L → H2O + succinate + ambiguine K + CO2
hydrogen peroxide + baicalein → 2 H2O + 6,7-dehydrobaicalein
L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate → H2O + L-tryptophan + D-glyceraldehyde 3-phosphate
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + spheroiden-2-ol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2,2-dihydroxyspheroidene + H2O
H2O + tauropine + NAD+ ← taurine + NADH + pyruvate + H+
tetrahydrothiophene 1-oxide + a reduced electron donor → an oxidized electron donor + H2O + tetrahydrothiophene
2 H+ + 2-oxoglutarate + oxygen → 3 CO2 + H2O + ethene
2 catechol + oxygen → 2 H2O + 2 1,2-benzoquinone
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + cholest-4-en-3-one + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + (25R)-26-hydroxycholest-4-en-3-one
NADPH + H+ + oxygen + 1-deoxy-11-oxopentalenate → H2O + NADP+ + neopentalenolactone D
2 H2O + 3 NAD+ + ammonium ← 3 NADH + 5 H+ + nitrite
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 2,3,4-tribromo-1H-pyrrole + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + hexabromo-2,2'-bipyrrole
a reduced electron donor + all-trans-4,4'-diaponeurosporene + oxygen → an oxidized electron donor + H2O + 4,4'-diaponeurosporen-1-ol
H2O + carboxynorspermidine + NADP+ ← L-aspartate 4-semialdehyde + propane-1,3-diamine + NADPH + H+
4'-hydroxyechinenone + a reduced electron donor + oxygen → an oxidized electron donor + H2O + 4',4'-dihydroxyechinenone
NADPH + H+ + echinocandin C + oxygen → H2O + NADP+ + echinocandin B
UDP-N-acetyl-α-D-glucosamine → H2O + UDP-2-acetamido-2,6-dideoxy-α-D-xylo-hex-4-ulose
a reduced electron donor + oxygen + holyrine A → an oxidized electron donor + H2O + holyrine B
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + pentalenolactone F → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + pentalenolactone
15 H+ + 2 malonyl-CoA + 5 (S)-methylmalonyl-CoA + 7 NADPH + (2S)-ethylmalonyl-CoA → 3 H2O + 7 NADP+ + 8 coenzyme A + 8 CO2 + tylactone
hydrogen peroxide + (S)-2-hydroxypropylphosphonate → 2 H2O + fosfomycin
UTP → H2O + dUTP
7S-hydroperoxy,17R-hydroxy-docosahexaenoate → 7(8)-epoxy-17R-hydroxy-docosahexaenoate + H2O
2 L-arginine + 3 NAD(P)H + 4 oxygen + H+ → 2 L-citrulline + 2 nitric oxide + 3 NAD(P)+ + 4 H2O
NADPH + 8-(methylsulfanyl)octyl-glucosinolate + H+ + oxygen → H2O + NADP+ + 8-(methylsulfinyl)octyl-glucosinolate
(3R)-4-(2-aminophenyl)-3-hydroxy-2,4-dioxobutanoate → H2O + 3-hydroxykynurenate
glycerol → H2O + 3-hydroxypropanal
NADPH + (E)-4-coumaroyl-CoA + H+ + oxygen → H2O + NADP+ + trans-caffeoyl-CoA
(3R)-hydroxydihomo γ-linolenoyl-CoA → H2O + (2E,8Z,11Z,14Z)-icosatetraenoyl-CoA
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + (25S)-26-hydroxycholest-4-en-3-one + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + (25S)-26-oxocholest-4-en-3-one
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-16:0-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-16:0-monogalactosyldiacylglycerol
14-demethyllanosterol + NADH + H+ + oxygen → 4β-hydroxymethyl-4α-methyl-5α-cholesta-8,24-dien-3β-ol + H2O + NAD+
6 H+ + 6 malonyl-CoA + acetyl-CoA → 7 coenzyme A + 7 CO2 + H2O + aloesone
dopamine + (4-hydroxyphenyl)acetaldehyde → H2O + (S)-norcoclaurine
NADH + H+ + toluene + oxygen → H2O + NAD+ + 4-methylphenol
glutathione + 1-(1H-indol-3-yl)-2-aci-nitroethane → H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-2-(1H-indol-3-yl)ethan-1-imine
L-glutamine + D-glyceraldehyde 3-phosphate + aldehydo-D-ribose 5-phosphate → 3 H2O + pyridoxal 5'-phosphate + H+ + L-glutamate + phosphate
(25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-al + NADPH + oxygen → H2O + NADP+ + (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate
a reduced electron donor + oxygen + β-zeacarotene → an oxidized electron donor + hydroxy-β-zeacarotene + H2O
2-oxoglutarate + oxygen + (2S)-eriodictyol → H2O + luteolin + succinate + CO2
hispidin + NADPH + H+ + oxygen → H2O + 3-hydroxyhispidin + NADP+
2 NADPH + 2 H+ + trichloroethene + oxygen → 2 NADP+ + H2O + trichloroethanol
(3R)-3-hydroxy-cerotoyl-CoA → H2O + trans-cerot-2-enoyl-CoA
hydrogen peroxide + catharanthine + vindoline → 2 H2O + α-3',4'-anhydrovinblastine radical
2-oxoglutarate + oxygen + apiforol → 2 H2O + succinate + apigeninidin + CO2
(2R)-2,3-dihydroxy-3-methylbutanoate → H2O + 3-methyl-2-oxobutanoate
zeaxanthin + a reduced electron donor + oxygen → an oxidized electron donor + 4-hydroxyzeaxanthin + H2O
2 a reduced electron donor + 2 oxygen + 4,4'-diapolycopene-4-al → 2 an oxidized electron donor + 3 H2O + 4,4'-diapolycopen-4,4'-dial
NADPH + 20-oxo-5-O-β-mycaminosyltylactone + H+ + oxygen → H2O + 5-O-β-mycaminosyltylonolide + NADP+
2 NADPH + 2 H+ + 2-nitrophenol + oxygen → 2 NADP+ + H2O + catechol + nitrite
FMNH2 + isethionate + oxygen → 2 H+ + FMN + H2O + glycolaldehyde + sulfite
2-oxo-3-(phosphooxy)propyl 3-oxodecanoate → H2O + (4-octanoyl-5-oxo-2H-furan-3-yl)methyl phosphate
NADPH + O4,O5--dimethylthujaplicatin + H+ + oxygen → 2 H2O + (-)-yatein + NADP+
p-cymene + NADH + H+ + oxygen → H2O + 4-isopropylbenzyl alcohol + NAD+
FADH2 + monodechloroaminopyrrolnitrin + chloride + oxygen → 2 H2O + FAD + aminopyrrolnitrin
brassinolide + a reduced electron donor + oxygen → an oxidized electron donor + H2O + 26-hydroxybrassinolide
4,4'-diaponeurosporen-1,1-diol → H2O + 4,4'-diaponeurosporenal
cholesterol + NAD(P)H + H+ + oxygen → 2 H2O + 7-dehydrocholesterol + NAD(P)+
D-ribulose 5-phosphate + L-tryptophan → hydroxyacetone + H2O + formaldehyde + H+ + phosphate + (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate
2-oxoglutarate + oxygen + gibberellin A34 → H2O + H+ + succinate + gibberellin A34-catabolite + CO2
2 veratryl alcohol + hydrogen peroxide → 2 H2O + 2 veratryl alcohol radical
2 a reduced electron donor + 2 oxygen + zeaxanthin → 2 an oxidized electron donor + 3 H2O + adonixanthin
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-linoleoyl-2-palmitoyl-phosphatidylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-linoleoyl-2-(3E)-hexadecenoyl-phosphatidylglycerol
a reduced electron donor + oxygen + solavetivone → an oxidized electron donor + H2O + 15-hydroxysolavetivone
NADPH + H+ + (2-aminobenzoyl)acetate + oxygen → H2O + NADP+ + 2-(hydroxylamino)benzoylacetate
7-O-methylluteone + NADPH + H+ + oxygen → H2O + 7-O-methylluteone epoxide + NADP+
2 2-aminophenol + an oxidized electron donor + oxygen → 2 H2O + isophenoxazine + a reduced electron donor
NADPH + H+ + (Z)-phenylacetaldehyde oxime + L-cysteine + oxygen → 2 H2O + (Z)-1-(L-cystein-S-yl)-N-hydroxy-2-phenylethan-1-imine + NADP+
2-isopropylphenol + NADH + H+ + oxygen → 3-isopropylcatechol + H2O + NAD+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:1-2-16:2-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:1-2-16:3-monogalactosyldiacylglycerol
L-phenylalanine + oxygen → H2O + 2-phenylacetamide + CO2
N-hydroxy-N-succinyl-putrescine + NADPH + H+ + oxygen → 3-[4-amino-3-hydroxybutyl]-hydroxy-carbamoyl-propanoate + H2O + NADP+
a reduced electron donor + oxygen + echinenone → an oxidized electron donor + 4'-hydroxyechinenone + H2O
a reduced electron donor + oxygen + (-)-vetispiradiene → an oxidized electron donor + H2O + solavetivone
NADPH + coniferaldehyde + H+ + oxygen → H2O + 5-hydroxy-coniferaldehyde + NADP+
aldehydo-L-galactonate → H2O + 2-dehydro-3-deoxy-L-galactonate
NADPH + L-lysine + oxygen → H2O + N6-hydroxy-L-lysine + NADP+
ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ammonium → H2O + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine
NAD(P)H + caffeine + H+ + oxygen → H2O + NAD(P)+ + paraxanthine + formaldehyde
FMNH2 + 3-(N-morpholino)propanesulfonate + oxygen → 2 H+ + FMN + H2O + 3-(N-morpholino)propanal + sulfite
(25R)-5β-cholestane-3α,7α,12α,26-tetraol + NADPH + H+ + oxygen → 2 H2O + (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-al + NADP+
FADH2 + 8-demethylnovobiocic acid + chloride + oxygen → 2 H2O + FAD + clorobiocic acid
NADPH + H+ + vitamin D3 + oxygen → H2O + NADP+ + calcidiol
FMNH2 + adamantanone + oxygen → FMN + H2O + 4-oxahomoadamantan-5-one + H+
2-[hydroperoxy(4-hydroxyphenyl)methyl]-6-hydroxy-1-benzofuran-3-one + a reduced electron donor → an oxidized electron donor + H2O + 6-hydroxy-2-[hydroxy-(4-hydroxyphenyl)methyl]-1-benzofuran-3-one
(3R,4R)-3-(6-hydroxy-1,3-benzodioxol-5-yl)-3,4-dihydro-2H-chromene-4,7-diol → H2O + 7,2'-dihydroxy-4',5'-methylenedioxyisoflav-3-ene
2-oxoglutarate + H+ + chloride + oxygen + 12-epi-hapalindole C → H2O + succinate + 12-epi-hapalindole E + CO2
8-aminooctan-4-one → H2O + γ-coniceine
NADPH + (E)-4-(methylsulfanyl)butanal oxime + H+ + L-cysteine + oxygen → 2 H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine + NADP+
NADH + 1,3,7-trimethylurate + H+ + oxygen → H2O + 1,3,7-trimethyl-5-hydroxyisourate + NAD+
3-α(S)-strictosidine → 2 H2O + CO2 + strictosamide
5 H+ + 5 malonyl-CoA → 5 coenzyme A + 5 CO2 + H2O + 1,3,6,8-naphthalenetetrol
1,3,7-trihydroxyxanthone + NADPH + H+ + oxygen → H2O + 1,3,6,7-tetrahydroxyxanthone + NADP+
(3R,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol → H2O + (-)-medicarpin
NADPH + H+ + oxygen + 20-hydroxy-13-14 epoxy-prefusarin → H2O + NADP+ + 20-hydroxy-fusarin
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + methymycin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + novamethymycin
L-serine + indole → H2O + L-tryptophan
4 1,2-benzoquinone monoimine + oxygen → 2 H2O + 2 isophenoxazine
NADPH + H+ + oxygen + griseophenone C → 2 H2O + NADP+ + desmethyl-dehydro-dechlorogriseofulvin
L-rhamnonate → H2O + 2-dehydro-3-deoxy-L-rhamnonate
(3R)-3-hydroxy-lignoceroyl-CoA → H2O + trans-lignocer-2-enoyl-CoA
NADPH + ergosta-5,7,24(28)-trien-3β-ol + H+ + oxygen → 2 H2O + ergosta-5,7,22,24(28)-tetraen-3-β-ol + NADP+
NADPH + caranine + H+ + oxygen → H2O + lycorine + NADP+
H2O + β-alanopine + NAD+ ← β-alanine + NADH + pyruvate + H+
NADPH + H+ + oxygen + griseophenone B → 2 H2O + NADP+ + desmethyl-dehydro-griseofulvin
NADH + butan-1-al + oxygen → H2O + butanoate + NAD+
2 ATP + S-adenosyl-L-methionine + (S)-1-pyrroline-5-carboxylate + L-arginine → 2 H+ + 2 diphosphate + 2 AMP + H2O + S-adenosyl-L-homocysteine + peramine
NADPH + H+ + oxygen + albendazole → H2O + albendazole s-oxide + NADP+
N'-hydroxymethyl-norcotinine + NADPH + oxygen → H2O + NADP+ + norcotinine
oleate + a reduced electron donor + oxygen → 2 H2O + an oxidized electron donor + linoleate
(6S)-hydroxyhyoscyamine + 2-oxoglutarate + oxygen → H2O + scopolamine + H+ + succinate + CO2
NAD(P)H + H+ + deoxybrevianamide E + oxygen → H2O + NAD(P)+ + 6-hydroxy-deoxybrevianamide E
NADH + H+ + oxygen + (2-hydroxy-1H-indol-3-yl)acetate → H2O + NAD+ + 3-hydroxy-2-oxo-(indol-3-yl)acetate
L-lyxonate → H2O + 2-dehydro-3-deoxy-L-arabinonate
NAD(P)H + theophylline + H+ + oxygen → H2O + 3-methylxanthine + NAD(P)+ + formaldehyde
4-toluenesulfonate + NADH + H+ + oxygen → H2O + 4-sulfobenzyl alcohol + NAD+
levopimaradiene + NADPH + H+ + oxygen → H2O + NADP+ + levopimaradienol
2 H+ + 3 NADPH + 3 oxygen + obtusifoliol → 3 NADP+ + 4 H2O + 4α-methyl-5α-ergosta-8,14,24(28)-trien-3β-ol + formate
NADPH + H+ + lithocholate + oxygen → H2O + NADP+ + hyodeoxycholate
2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate ← 2 a reduced ferredoxin [iron-sulfur] cluster + 2-C-methyl-D-erythritol-2,4-cyclodiphosphate + H+
(1Z,2S)-2-methylbutanal oxime → H2O + (2S)-methylbutanenitrile
NADPH + H+ + benzoyl-CoA + oxygen → H2O + NADP+ + 3-hydroxybenzoyl-CoA
NADPH + H+ + emindole-SB + oxygen → H2O + NADP+ + 14,15-epoxyemindole-SB
2 FMNH2 + dibenzothiophene-5,5-dioxide + oxygen → 2 FMN + 3 H+ + H2O + 2'-hydroxybiphenyl-2-sulfinate
4α-formyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + oxygen → H2O + NAD(P)+ + 4α-carboxy-5α-cholesta-8,24-dien-3β-ol
hydroxyacetone + NADPH + H+ + oxygen → H2O + hydroxymethylene acetate + NADP+
NADPH + cyclohexane + H+ + oxygen → H2O + cyclohexanol + NADP+
2-nonaprenyl-6-methoxyphenol + oxygen → H2O + 2-nonaprenyl-6-methoxy-1,4-benzoquinone
a reduced electron donor + urolithin M5 → an oxidized electron donor + H2O + urolithin M6
2 hispidin + hydrogen peroxide → 2 H2O + 3,14'-bihispidinyl
phylloquinone + a reduced electron donor + oxygen → an oxidized electron donor + H2O + vitamin K 2,3-epoxide
NADPH + H+ + luteolin + oxygen → H2O + 8-hydroxy-luteolin + NADP+
ethylamine + NADPH + H+ + oxygen → H2O + acetaldehyde + NADP+ + ammonium
a reduced electron donor + 2,4,6-trinitrotoluene → an oxidized electron donor + H2O + 4-nitroso-2,6-dinitrotoluene
2 H+ + a reduced electron donor + oxygen + dihydrogeodin → 2 H2O + an oxidized electron donor + geodin
taxa-4,11-diene + a reduced electron donor + oxygen → an oxidized electron donor + H2O + taxa-4(20),11-dien-5α-ol
4β-formyl-4α-methyl-5α-cholesta-8,24-dien-3β-ol + NADH + oxygen → H2O + NAD+ + 4β-carboxy-4α-methyl-5α-cholesta-8,24-dien-3β-ol
2 a reduced ferredoxin [iron-sulfur] cluster + (25S)-26-oxocholesterol + H+ + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + (25S)-3β-hydroxycholest-5-en-26-oate + H2O
tetracenomycin F2 → H2O + tetracenomycin F1
2 L-alanine + N-acetyldemethyl-L-phosphinothricin → 2 H2O + N-acetyldemethylphosphinothricin tripeptide
2 hydroxyl radical + dGTP → H2O + 8-oxo-dGTP
NAD(P)H + γ-glutamyl-isopropylamide + H+ + oxygen → H2O + N-(γ-L-glutamyl)-L-alaninol + NAD(P)+
2 phenylmethanesulfenate → H2O + petivericin
NADPH + lyngbyatoxin A + H+ + oxygen → H2O + lyngbyatoxin B + NADP+
3 malonyl-CoA + 4 H+ + NADPH + (E)-4-coumaroyl-CoA → 3 CO2 + 4 coenzyme A + H2O + isoliquiritigenin + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 10-deoxymethymycin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + neomethymycin
H2O + N5-(L-1-carboxyethyl)-L-ornithine + NADP+ ← L-ornithine + NADPH + pyruvate + H+
D-galactarate → H2O + 5-dehydro-4-deoxy-D-glucarate
10-formyltetrahydrofolate-4a-carbinolamine → N10-formyldihydrofolate + H2O
D-glucarate → H2O + 5-dehydro-4-deoxy-D-glucarate
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 15-methyl-palmitate + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 16-hydroxy-15-methyl-palmitate
ammonium + UDP-N-acetyl-β-L-fucosamine → H2O + UDP-2,6-dideoxy-2-acetamidino-β-L-galactose
a reduced electron donor + α-linolenoyl-CoA + oxygen → 2 H2O + an oxidized electron donor + stearidonoyl-CoA
2-oxoglutarate + oxygen + neopentalenolactone D → H2O + succinate + neopentalenolactone E + CO2
2 L-cysteine + salicylate + NADPH + S-adenosyl-L-methionine → 4 H2O + S-adenosyl-L-homocysteine + NADP+ + pyochelin
H2O + 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido[4,5-b][1,4]diazepin-4-one + glutathione disulfide ← 2 glutathione + (6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin
D-arabinonate → H2O + 2-dehydro-3-deoxy-D-arabinonate
4 H+ + an oxidized electron donor + isethionate + oxygen → 2 H2O + sulfoacetaldehyde + a reduced electron donor
2-oxoglutarate + H+ + chloride + oxygen + ambiguine J → H2O + succinate + ambiguine D + CO2
NADPH + 6-methylpretetramide + H+ + oxygen → H2O + 4-hydroxy-6-methylpretetramide + NADP+
2 laurate + 2 H+ + lesquerella oil → 2 H2O + triglyceride estolide
campestanol + a reduced electron donor + oxygen → an oxidized electron donor + H2O + (6α)-hydroxycampestanol
2 coniferyl alcohol + hydrogen peroxide → 2 H2O + 2 coniferyl alcohol radical
H2O + NAD+ + nitrite ← NADH + H+ + nitrate
NADPH + H+ + 2-methoxy-6-(all-trans-nonaprenyl)phenol + oxygen → H2O + 2-methoxy-6-all trans-nonaprenyl-1,4-benzoquinol + NADP+
2 NADPH + 2 H+ + 4-nitrotoluene → 2 NADP+ + H2O + 4-hydroxylaminotoluene
NADPH + (E)-9-(methylsulfanyl)nonanal oxime + H+ + L-cysteine + oxygen → 2 H2O + (E)-1-(L-cystein-S-yl)-N-hydroxy-ω-(methylsulfanyl)nonan-1-imine + NADP+
NADPH + 5a,11a-dehydrotetracycline + H+ + oxygen → H2O + NADP+ + 5a,11a-dehydrooxytetracycline
a reduced electron donor + H+ + oxygen + 15-demethoxyaclacinomycin T → an oxidized electron donor + H2O + 10-decarboxymethylaclacinomycin T + CO2
fluorobenzene + NADH + H+ + oxygen → 4-fluorophenol + H2O + NAD+
4α-hydroxymethyl-5α-cholesta-8-en-3β-ol + NAD(P)H + H+ + oxygen → 2 H2O + 4α-formyl-5α-cholesta-8-en-3β-ol + NAD(P)+
NADH + 2-heptyl-4-quinolone + H+ + oxygen → H2O + 2-heptyl-3-hydroxy-4-quinolone + NAD+
4-hydroxylamino-2,6-dinitrotoluene + UDP-α-D-glucose → H2O + 4-hydroxylamino-2,6-dinitrotoluene 3C-glucoside + UDP
2 NADPH + 2 H+ + 2 oxygen + L-phenylalanine → 2 NADP+ + 3 H2O + (E)-phenylacetaldehyde oxime + CO2
gentisyl alcohol + oxygen → H2O + phyllostine
a reduced electron donor + ferroheme i + oxygen → an oxidized electron donor + H2O + hydroxyferroheme i
NAD(P)H + 4-nitrocatechol + oxygen → H2O + 2-hydroxy-1,4-benzoquinone + NAD(P)+ + H+ + nitrite
(2S)-liquiritigenin + NAD(P)H + oxygen → H2O + NAD(P)+ + licodione
FADH2 + 2-methylpropan-1-amine + oxygen → 2 H+ + FAD + H2O + N-(2-methylpropyl)hydroxylamine
3,4',4'-trihydroxyechinenone → H2O + adonirubin
an oxidized electron donor + H2O + nitrite ← a reduced electron donor + nitrate
(3R,4R)-3-(6-hydroxy-1,3-benzodioxol-5-yl)-3,4-dihydro-2H-chromene-4,7-diol → H2O + (-)-maackiain
1-(3,4-dihydroxyphenyl)-3-(3-C-glucosyl-2,4,6-trihydroxyphenyl)propane-1,3-dione → H2O + isoorientin
2 a reduced electron donor + 2 oxygen + all-trans-4,4'-diapolycopene → 2 an oxidized electron donor + 3 H2O + 4,4'-diapolycopene-4-al
1,3,5-trihydroxyxanthone + NADPH + H+ + oxygen → H2O + 1,3,5,6-tetrahydroxyxanthone + NADP+
torulene + oxygen → H2O + 4-ketotorulene
H2O + MMF3 butenolide intermediate → H2O + methylenomycin furan 3
2 emodin → 2 H2O + hypericin
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6-(D-ribitylamino)uracil → 2 H2O + 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ + phosphate
2 D-urobilinogen + oxygen → 2 H2O + 2 D-urobilin
anthranilate + FADH2 + oxygen → FAD + H2O + 3-hydroxyanthranilate + H+
NAD(P)H + H+ + oxygen + 20-dihydro-chaetoglobosin A → 2 H2O + NAD(P)+ + chaetoglobosin A
L-ascorbate + H+ + oxygen + tyramine → H2O + L-dehydro-ascorbate + octopamine
NADPH + 5-O-β-mycaminosyltylactone + H+ + oxygen → H2O + 20-hydroxy-5-O-mycaminosyltylactone + NADP+
NADPH + H+ + oxygen + α-carotene → zeinoxanthin + H2O + NADP+
N,N-dihydroxypentahomomethionine + H+ → H2O + (E)-8-(methylsulfanyl)octanal oxime + CO2
NADPH + H+ + 3-nonaprenyl-4-hydroxybenzoate + oxygen → 3,4-dihydroxy-5-all-trans-nonaprenylbenzoate + H2O + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + H+ + (25R)-26-oxocholest-4-en-3-one + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + (25R)-3-oxocholest-4-en-26-oate
NADPH + 6-(methylsulfanyl)hexyl-glucosinolate + H+ + oxygen → H2O + NADP+ + 6-methylsulfinylhexyl-glucosinolate
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 3-oxo-4-pregnene-20-carboxyl-CoA + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 9α-hydroxy-androst-4-en-3-one-17-propanoyl-CoA
a reduced electron donor + arachidonate + oxygen → an oxidized electron donor + H2O + 15S-hydroxypentaenoate
NADPH + H+ + (+)-sabinene + oxygen → H2O + (+)-cis-sabinol + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + H+ + nocardicin C + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 2'-N-hydroxy-nocardicin c
a reduced electron donor + oxygen + adonixanthin → an oxidized electron donor + H2O + 4'-hydroxyadonixanthin
NADPH + H+ + (4S)-limonene + oxygen → H2O + (4S)-perillyl alcohol + NADP+
butan-1-al + norfuraneol → H2O + (2E)-2-butylidene-4-hydroxy-5-methyl-3(2H)-furanone
3,4-dihydroxybenzaldehyde + tyramine → H2O + norcraugsodine + H+
NADPH + H+ + oxygen + 13-dihydrocarminomycin → 2 H2O + NADP+ + carminomycin
zeaxanthin + NADH + H+ + oxygen → caloxanthin + H2O + NAD+
NADPH + sitosterol + H+ + oxygen → 2 H2O + NADP+ + stigmasterol
α-cembratriene-ol + NAD(P)H + H+ + oxygen → α-cembratriene-4,6-diol + H2O + NAD(P)+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + alachlor + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + methyl formate + 2-chloro-N-(2,6-diethylphenyl)acetamide
H2O + (S)-2,3,4,5-tetrahydrodipicolinate + NADP+ ← NADPH + H+ + (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate
1-(methylsulfanyl)-4-aci-nitrobutane + glutathione → H2O + (E)-1-(glutathion-S-yl)-N-hydroxy-ω-(methylsulfanyl)butan-1-imine
17S-hydroperoxydocosahexaenoate + a reduced electron donor + oxygen → an oxidized electron donor + H2O + 4S-hydroperoxy,17S-hydroxy-docosahexaenoate
hydratedusnate → H2O + (S)-usnate
NADPH + 4-hydroxy-6-methylpretetramide + H+ + oxygen → H2O + 4-dedimethylamino-4-oxoanhydrotetracycline + NADP+
4 malonyl-CoA + 5 H+ + NADPH + acetyl-CoA → 4 CO2 + 5 coenzyme A + 6-hydroxymellein + H2O + NADP+
a reduced electron donor + urolithin M5 → an oxidized electron donor + H2O + urolithin E
antheraxanthin + L-ascorbate + H+ → zeaxanthin + H2O + L-dehydro-ascorbate
2 H+ + NADPH + 4-hydroxybenzoate + bromide + oxygen → 2 H2O + NADP+ + 3-bromo-4-hydroxybenzoate
2 H+ + 4 oxygen + 5 a reduced electron donor + protoheme → 4 H2O + 5 an oxidized electron donor + Fe2+ + formaldehyde + β-staphylobilin
oxygen + O-methylandrocymbine → H2O + N-formyldemecolcine
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + choline + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + betaine aldehyde hydrate
NADPH + H+ + oxygen + pentalenene → H2O + NADP+ + pentalen-13-ol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:2-2-18:3-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:3-2-18:3-monogalactosyldiacylglycerol
secologanin + tryptamine → H2O + 3-α(S)-strictosidine
NADPH + H+ + (25R)-5β-cholestane-3α,7α,26-triol + oxygen → 2 H2O + NADP+ + (25R)-3α,7α-dihydroxy-5β-cholestan-26-al
12 H+ + 5 NADPH + 6 (S)-methylmalonyl-CoA + malonyl-CoA → 2 H2O + 5 NADP+ + 7 coenzyme A + 7 CO2 + narbonolide
NADPH + H+ + oxygen + palustradienol → H2O + NADP+ + palustradiene-diol
hydrogen peroxide + palmitate + H+ → 2 H2O + 1-pentadecene + CO2
FADH2 + 2,6-dichlorohydroquinone + H+ + oxygen → FAD + H2O + 6-chlorohydroxyquinol + chloride
12-ethyl-71,71-dihydroxy-8-propylbacteriochlorophyllide c → H2O + 12-ethyl-8-propylbacteriochlorophyllide e
NADPH + H+ + 2-methoxy-6-(all-trans-heptaprenyl)phenol + oxygen → H2O + 2-methoxy-6-all trans-heptaprenyl-1,4-benzoquinol + NADP+
2',4,4',6'-tetrahydroxychalcone 4'-O-β-D-glucoside + oxygen → H2O + aureusidin 6-O-glucoside
(13S)-HPODE → (ω5Z)-etheroleate + H2O
(S)-malyl α-D-glucosaminide + L-cysteine → H2O + bacillithiol
2 L-glutamine + acetyl-CoA → coenzyme A + H2O + H+ + N-acetyl-L-glutaminyl-L-glutamine
GDP-N-acetyl-D-glucosamine → GDP-2-acetamido-2,6-dideoxy-α-D-xylo-hexos-4-ulose + H2O
FMNH2 + ethylenediaminetriacetate + oxygen → FMN + H2O + ethylenediamine-N,N'-diacetate + glyoxylate + H+
FADH2 + melleolide F + chloride + oxygen → 2 H2O + FAD + 6'-chloromelleolide F
octanoyl-CoA + H+ + (2-aminobenzoyl)acetate → coenzyme A + H2O + 2-heptyl-4-quinolone + CO2
NAD(P)H + aurachin C + H+ + oxygen → H2O + NAD(P)+ + 4-hydroxy-2-methyl-3-oxo-4-farnesyl-3,4-dihydroquinoline-1-oxide
FADH2 + (1E,3S,4Z)-7-amino-1-{3-[(1E)-prop-1-en-1-yl]oxiran-2-yl}hepta-1,4-dien-3-ol + oxygen → FAD + H2O + (1S,2Z)-5-amino-1-(3-{3-[(1E)-prop-1-en-1-yl]oxiran-2-yl}oxiran-2-yl)pent-2-en-1-ol + H+
1-hydroxyneurosporene + a reduced electron donor + oxygen → 2 H2O + an oxidized electron donor + demethylspheroidene
2 a reduced electron donor + (2S)-2-[(E)-[(2S)-2-amino-3-(4-hydroxyphenyl)propylidene]amino]-3-(4-hydroxyphenyl)propanal → 2 an oxidized electron donor + H2O + 4-{[(2S,5S)-5-[(4-hydroxyphenyl)methyl] piperazin-2-yl]methyl}phenol
H+ + 5'-oxoaverantin → H2O + (1'S,5'S)-averufin
2 2',3,4,4',6'-pentahydroxychalcone 4'-O-β-D-glucoside + oxygen → 2 H2O + 2 aureusidin 6-O-glucoside
15 H+ + 3 malonyl-CoA + 5 (S)-methylmalonyl-CoA + 7 NADPH → 4 H2O + 7 NADP+ + 8 coenzyme A + 8 CO2 + protomycinolide IV
hydrogen peroxide + betanidin → 2 H2O + betanidin quinone
4,4-dimethyl-14α-formyl-5α-cholesta-8-en-3β-ol + NADPH + oxygen → 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + H2O + formate + NADP+
2 L-ascorbate + hydrogen peroxide + H+ → 2 H2O + L-ascorbate + L-dehydro-ascorbate
oxygen + 1-[4,5,7,10-tetrahydroxy-3-(3-oxobutanoyl)anthracen-2-yl]pentane-1,2,4-trione → H2O + premithramycinone G
NADPH + H+ + bisphenol A + oxygen → H2O + NADP+ + 1,2-bis(4-hydroxyphenyl)-2-propanol
D-ribulose 5-phosphate + L-tyrosine → hydroxyacetone + H2O + formaldehyde + H+ + phosphate + (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate
palustradiene + NADPH + H+ + oxygen → H2O + NADP+ + palustradienol
2 NADH + 2 H+ + 2 oxygen + zeaxanthin → 2 H2O + 2 NAD+ + nostoxanthin
2 oxygen + a reduced electron donor + 2-oxoglutarate + fumitremorgin B → an oxidized electron donor + H2O + verruculogen + succinate + CO2
FADH2 + resorcinol + oxygen → FAD + H2O + H+ + hydroxyquinol
(3R)-2'-hydroxydihydrodaidzein → H2O + 3,9-dihydroxypterocarp-6a-en
2 hydroxyl radical + 2'-deoxyadenosine → H2O + 2-oxo-2'-deoxyadenosine
(3R,4R)-7,2',4'-trihydroxyisoflavanol → H2O + (6aR,11aR)-3,9-dihydroxypterocarpan
3-methoxytyramine + betalamate → H2O + H+ + betaxanthin
2 a reduced electron donor + 2 oxygen + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate → 2 an oxidized electron donor + 2 H2O + 17R-hydroperoxydocosahexaenoate
NADPH + H+ + 2-hexaprenyl-6-methoxyaminobenzene + oxygen → H2O + NADP+ + 2-hexaprenyl-6-methoxyaminophenol
(1R,4S)-1-hydroxymenth-8-en-2-one + NADPH + oxygen → (3S)-3-isopropenyl-6-oxoheptanoate + H2O + NADP+
NAD(P)H + H+ + CMP-N-acetyl-β-neuraminate + oxygen → H2O + NAD(P)+ + CMP-N-glycoloyl-β-neuraminate
(3R,8Z,11Z,14Z,17Z)-3-hydroxyicosatetraenoyl-CoA → H2O + (2E,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA
3-(1H-indol-3-yl)propanoate + hydroxyl radical → H2O + 3-(1H-indol-3-yl)propanoate cation radical
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + β-cryptoxanthin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + zeaxanthin + H2O
2 a reduced ferredoxin [iron-sulfur] cluster + H+ + 18-oxo candicinolide + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 18-carboxy candicinolide
NADPH + H+ + oxygen + 6-methoxy-3-methyl-2-all-trans-heptaprenyl-1,4-benzoquinol → H2O + 3-demethylubiquinol-7 + NADP+
hydrogen peroxide + indole → H2O + indolin-3-one
2 oxygen + 4 a reduced ferredoxin [iron-sulfur] cluster + 4 H+ + pentalenene → 3 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + pentalen-13-al
4-chloro-3-hydroxybutyryl-CoA → H2O + 4-chloro-crotonyl-CoA
(4S)-2,3-dehydroleucopelargonidin + H+ → pelargonidin + H2O
17R-hydroperoxydocosahexaenoate + NADPH + H+ → 17R-hydroxydocosahexaenoate + H2O + NADP+
8-methyl-6-nonenoate + vanillylamine → H2O + capsaicin
3,5-dioxo-6-[4,5,7-trihydroxy-3-(3-oxobutanoyl)naphthalen-2-yl]hexanoate → H2O + tetracenomycin F2
cyclooctat-9-en-5,7-diol + a reduced electron donor + oxygen → an oxidized electron donor + cyclooctatin + H2O
2 oxygen + 4 a reduced ferredoxin [iron-sulfur] cluster + 4 H+ + canthaxanthin → 2 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + (3S,3'S)-astaxanthin
(6E)-8-hydroxylinalool + NADH + H+ + oxygen → 2 H2O + (6E)-8-oxolinalool + NAD+
4-hydroxy-4,4'-diapolycopene + a reduced electron donor + oxygen → an oxidized electron donor + 4,4-dihydroxy-4,4'-diapolycopene + H2O
NADH + acetone + H+ + oxygen → hydroxyacetone + H2O + NAD+
a reduced electron donor + oxygen + gibberellin A37 (closed lactone form) → an oxidized electron donor + H2O + gibberellin A38
H+ + oxygen + deoxyviolaceinate → H2O + CO2 + deoxyviolacein
2 H+ + 3 NAD(P)H + 3 oxygen + 4α-methyl-5α-cholesta-8,24-dien-3β-ol → 3 NAD(P)+ + 4 H2O + 4α-carboxy-5α-cholesta-8,24-dien-3β-ol
NADPH + H+ + oxygen + deoxynortryptoquialanone → H2O + NADP+ + tryptoquialanone
FMNH2 + methanesulfonate + oxygen → 2 H+ + FMN + H2O + formaldehyde + sulfite
NADPH + squalene + H+ + oxygen → H2O + NADP+ + (3S)-2,3-epoxy-2,3-dihydrosqualene
diethylamine + NADPH + oxygen → H2O + NADP+ + diethylamine N-oxide
3,5,7,9,11,13,15,17,19-nonaoxoicosanoate → 2 H2O + 3,5-dioxo-6-[4,5,7-trihydroxy-3-(3-oxobutanoyl)naphthalen-2-yl]hexanoate
NADPH + neoabietadienal + oxygen → H2O + NADP+ + neoabietic acid
UDP-N-acetyl-α-D-glucosamine → H2O + UDP-6-deoxy-5,6-ene-N-acetyl-D-glucosamine
FMNH2 + 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + oxygen → FMN + 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + H+
NADPH + H+ + oxygen + calcidiol → H2O + NADP+ + secalciferol
2 indole-3-carbinol → H2O + formaldehyde + 3,3'-di(indol-3-yl)methane
2 H+ + 4 a reduced electron donor + 4 oxygen + protoheme → 4 an oxidized electron donor + 4 H2O + Fe2+ + δ-staphylobilin + carbon monoxide
NADH + H+ + 3-chlorotoluene + oxygen → H2O + 3-chlorobenzyl alcohol + NAD+
glycerone phosphate + L-aspartate + oxygen → 2 H2O + quinolinate + hydrogen peroxide + H+ + phosphate
UWM6 + oxygen → 2 H2O + rabelomycin
2 H+ + 4 glutathione + selenite → 3 H2O + glutathione disulfide + selenodiglutathione
2 H+ + 4-nitrophenol + NADPH + oxygen → H2O + 4-nitrocatechol + NADP+
ent-kaurene + NADPH + H+ + oxygen → H2O + kauralexin A1 + NADP+
2 NADPH + 2 H+ + L-valine + L-tryptophan + L-methionine → 2 H2O + 2 NADP+ + L-homocysteine + N-methyl-L-valyl-L-tryptophanol
D-mannonate → H2O + 2-dehydro-3-deoxy-D-gluconate
7α,12α-dihydroxy-3-oxochol-4-en-24-oyl-CoA → H2O + 12α-hydroxy-3-oxochol-4,6-dien-24-oyl-CoA
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 1-18:1-2-16:0-monogalactosyldiacylglycerol + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 1-18:2-2-16:0-monogalactosyldiacylglycerol
FADH2 + 2,4,5-trichlorophenol + oxygen → FAD + 2,5-dichloro-p-quinone + H2O + H+ + chloride
2 a reduced electron donor + 2 oxygen + adonixanthin → 2 an oxidized electron donor + 3 H2O + (3S,3'S)-astaxanthin
phenol + NADH + H+ + oxygen → H2O + catechol + NAD+
NADPH + 5-(methylsulfanyl)pentyl-glucosinolate + H+ + oxygen → H2O + NADP+ + 5-(methylsulfinyl)pentyl-glucosinolate
NAD(P)H + H+ + (-)-maackiain + oxygen → H2O + NAD(P)+ + 1α-hydroxy-maackiain
Nω-hydroxy-L-arginine → H2O + guanidinium + H+ + (S)-1-pyrroline-5-carboxylate
(3S)-3-hydroxy-L-arginine → H2O + guanidinium + H+ + (S)-1-pyrroline-5-carboxylate
2,3-seco-dopa → H2O + muscaflavin + H+
2 oxygen + 4 a reduced ferredoxin [iron-sulfur] cluster + 4 H+ + spheroidene → 3 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + spheroiden-2-one
a reduced electron donor + 2'-hydroxypyridoxol → an oxidized electron donor + H2O + pyridoxine
7 H+ + 8 malonyl-CoA → 8 coenzyme A + 8 CO2 + H2O + octoketide 4b
5 H+ + 6 malonyl-CoA → 6 coenzyme A + 6 CO2 + H2O + hexaketide pyrone
NADH + H+ + oxygen + 2-hydroxyadonixanthin → H2O + NAD+ + 2,3,2',3'-tetrahydroxy-β,β-caroten-4-one
(R)-3-(phenyl)lactoyl-CoA → (E)-cinnamoyl-CoA + H2O
hydrogencarbonate + naphthalene → H2O + 2-naphthoate
a reduced electron donor + oxygen + cis-4-hydroxy-D-proline → 2 H2O + an oxidized electron donor + H+ + 1-pyrroline-4-hydroxy-2-carboxylate
NADH + H+ + 4-methylphenol + oxygen → H2O + 4-methylcatechol + NAD+
NADPH + H+ + quercetin + oxygen → H2O + NADP+ + gossypetin
loganin + NADPH + H+ + oxygen → 2 H2O + secologanin + NADP+
a reduced electron donor + oxygen + gibberellin A4 → 2 H2O + an oxidized electron donor + gibberellin A7
2 H+ + 3 NADH + 3 oxygen + 14-demethyllanosterol → 3 NAD+ + 4 H2O + 4β-carboxy-4α-methyl-5α-cholesta-8,24-dien-3β-ol
NADPH + H+ + oxygen + agroclavine → H2O + NADP+ + elymoclavine
hydroxylamine + oxygen → H2O + H+ + nitrite
2,2-dihydroxyspirilloxanthin → H2O + 2-oxospirilloxanthin
2 H+ + NADPH + oxygen + chrysin → H2O + NADP+ + baicalein
NADPH + geranylhydroquinone + H+ + oxygen → H2O + 3''-hydroxy-geranylhydroquinone + NADP+
NADH + (4R)-perillyl aldehyde + oxygen → H2O + NAD+ + (4R)-perillate
a reduced electron donor + oxygen + (+)-larreatricin → an oxidized electron donor + H2O + (+)-3'-hydroxylarreatricin
2-amino-4-carboxypyrimidine + H+ + L-serine → H2O + lathyrine + CO2
2,4',5,7-tetrahydroxyisoflavanone → H2O + genistein + H+
3 S-adenosyl-L-methionine + 3 H+ + 3 L-cysteine + 6 NADPH + (salicyl)adenylate + malonyl-CoA → 3 S-adenosyl-L-homocysteine + 6 NADP+ + 8 H2O + coenzyme A + yersiniabactin + AMP
2-oxoglutarate + oxygen + gibberellin A29 → H2O + H+ + succinate + gibberellin A29-catabolite + CO2
L-histidine + L-cysteine + oxygen → H2O + L-alanin-3-yl L-histidin-5-yl S-oxide
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 3-oxo-23,24-bisnorchol-4-en-22-oate + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 3-one-9-hydroxy-23,24-bisnorchol-4-en-22-oate
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 20-hydroxy-5-O-mycaminosyltylactone + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2O + 20-oxo-5-O-β-mycaminosyltylactone
4-methyl-5-nitrocatechol + NAD(P)H + oxygen → H2O + 2-hydroxy-5-methylquinone + NAD(P)+ + H+ + nitrite
NAD(P)H + H+ + oxygen + fuscofusarin → H2O + NAD(P)+ + dimeric 9-hydroxyrubrofusarin-fuscofusarin
2 H+ + 4-methylsalicylate + NADH + oxygen → H2O + 4-methylcatechol + NAD+ + CO2
3-dimethylallyl-4-hydroxymandelate + oxygen → H2O + 3-dimethylallyl-4-hydroxybenzoate + CO2
NADPH + (+)-dihydrocarvone + H+ + oxygen → H2O + NADP+ + (4R,7R)-4-isopropenyl-7-methyloxepan-2-one
a reduced electron donor + oxygen + echinenone → 2 H+ + an oxidized electron donor + H2O + canthaxanthin
6-hydroxy-allocryptopine → 2 H2O + dihydrochelerythrine
NAD(P)H + aurachin C + H+ + oxygen → H2O + NAD(P)+ + aurachin C epoxide
2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + isopentenyl diphosphate ← 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate
a reduced electron donor + (11Z)-hexadecenoyl-CoA + oxygen → 2 H2O + an oxidized electron donor + (10E,12Z)-10,12-hexadecadienoyl-CoA
2 1,2,3,4,6-pentagalloylglucose + oxygen → 2 H2O + 2 tellimagrandin II
NADH + H+ + (4R)-limonene + oxygen → H2O + (4R)-perillyl alcohol + NAD+
3R-hydroxy-lesqueroloyl-CoA → H2O + trans-lesqueroloyl-CoA
NADPH + H+ + 6-(all-trans-decaprenyl)-2-methoxy-phenol + oxygen → H2O + all trans-decaprenyl-2-methoxy-6-1,4-benzoquinol + NADP+
NADPH + (+)-dihydrocarvone + H+ + oxygen → H2O + NADP+ + (3R,6R)-6-isopropenyl-3-methyloxepan-2-one
pyrrole-2-carboxylate + NADH + H+ + oxygen → H2O + 5-hydroxypyrrole-2-carboxylate + NAD+
2 syringaldazine + oxygen → 2 H2O + 2 tetramethoxy azobismethylene quinine
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + zeaxanthin + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + antheraxanthin + H2O
4 a reduced ferredoxin [iron-sulfur] cluster + 5 H+ + 2-hexaprenyl-6-methoxyaminophenol + oxygen → 4 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 2-methoxy-6-all trans-hexaprenyl-1,4-benzoquinol + ammonium
2-amino-3-carboxymuconate-6-semialdehyde → H2O + quinolinate + H+
FADH2 + L-tryptophan + chloride + oxygen → 2 H2O + FAD + 6-chloro-L-tryptophan
71-dihydroxychlorophyllide a → H2O + chlorophyllide b
a reduced electron donor + oxygen + 3-hydroxyechinenone → an oxidized electron donor + H2O + 3,4'-dihydroxyechinenone
(R)-2,3-dihydroxy-3-methylpentanoate → H2O + (S)-3-methyl-2-oxopentanoate
3 H+ + 3 malonyl-CoA + acetyl-CoA + 1,4,5,10,13-pentahydroxy-Δ2,3-protoilludene → 3 CO2 + 4 coenzyme A + H2O + melledonol
NADPH + H+ + oxygen + pre-bikaverin → H2O + NADP+ + 7-hydroxy-pre-bikaverin
2 dopamine + oxygen → 2 H2O + 2 dopamine quinone
2-amino-2-deoxy-D-gluconate → (2Z,4S,5R)-2-amino-4,5,6-trihydroxyhex-2-enoate + H2O + H+
2 hydrogen peroxide → 2 H2O + oxygen
22 NADPH + 32 H+ + 5 malonyl-CoA + 5 (S)-methylmalonyl-CoA + heptanoyl-CoA → 10 coenzyme A + 10 CO2 + 11 H2O + 22 NADP+ + C32-mycoketide-CoA
ent-kaur-16-en-19-oate + NADPH + H+ + oxygen → steviol + H2O + NADP+
3 oxygen + 6 a reduced ferredoxin [iron-sulfur] cluster + 8 H+ + protoheme → 3 H2O + 6 an oxidized ferredoxin [iron-sulfur] cluster + Fe2+ + (Z,Z)-biliverdin-IX α + carbon monoxide
NADPH + H+ + 2,4-dichlorophenol + oxygen → H2O + NADP+ + 3,5-dichlorocatechol
NAD(P)H + H+ + oxygen + protoviolaceinate → H2O + NAD(P)+ + violaceinate
NADPH + trans-cinnamate + H+ + oxygen → H2O + 4-coumarate + NADP+
CTP → H2O + dCTP
NADPH + H+ + oxygen + 4-hydroxy-3-methylbenzoate → H2O + NADP+ + 4-hydroxy-3-(hydroxymethyl)-benzoate
(E)-(indol-3-yl)acetaldehyde oxime → H2O + (indole-3-yl)acetonitrile
chloroethene + NADH + H+ + oxygen → H2O + chlorooxirane + NAD+
dehydroabietadiene-diol → H2O + dehydroabietadienal
D-xylonate → H2O + 2-dehydro-3-deoxy-D-arabinonate
inosine + oxygen → H2O + 9-riburonosylhypoxanthine + H+
(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA → H2O + (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA
NADPH + H+ + 3-chlorophenol + oxygen → H2O + NADP+ + 4-chlorocatechol
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + dTDP-4-dehydro-2,6-dideoxy-α-D-threo-hexopyranose → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + dTDP-4-dehydro-2,3,6-trideoxy-α-D-hexopyranose
NADPH + H+ + oxygen + (+)-isodihydrocarvone → H2O + NADP+ + (3S,6R)-6-isopropenyl-3-methyloxepan-2-one
NADPH + quinine + H+ + oxygen → H2O + 3-hydroxyquinine + NADP+
NADPH + H+ + oxygen + notoamide E → H2O + NADP+ + notoamide C
psoralen + NADPH + H+ + oxygen → bergaptol + H2O + NADP+
(R)-10-Hydroxystearate → H2O + oleate
NADPH + dTDP-β-L-evernosamine + oxygen → H2O + dTDP-N-hydroxy-β-L-evernosamine + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 5-O-β-mycaminosyltylactone + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 20-hydroxy-5-O-mycaminosyltylactone
emodin dianthrone + a reduced electron donor + oxygen → 2 H2O + 2 H+ + an oxidized electron donor + protohypericin
NADPH + H+ + oxygen + benzoate → salicylate + H2O + NADP+
NADPH + H+ + 3-hexaprenyl-4-aminobenzoate + oxygen → H2O + NADP+ + 3-hexaprenyl-4-amino-5-hydroxybenzoate
cyclohexanone + NADPH + H+ + oxygen → H2O + NADP+ + ε-caprolactone
2 H+ + NADPH + oxygen + chlorophyllide a → H2O + NADP+ + 71-hydroxychlorophyllide a
NADPH + 20-dihydrorosamicin + H+ + oxygen → 2 H2O + NADP+ + rosamicin
(2S,3S)-2-methylcitrate → H2O + 2-methyl-trans-aconitate
NADPH + O-aminobenzaldehyde + oxygen → anthranilate + H2O + NADP+
2,4,6-trihydroxybenzophenone + NADPH + H+ + oxygen → H2O + 2,3',4,6-tetrahydroxybenzophenone + NADP+
NADPH + 2-hexaprenyl-6-methoxyphenol + H+ + oxygen → H2O + 2-methoxy-6-all trans-hexaprenyl-1,4-benzoquinol + NADP+
a reduced electron donor + oxygen + deoxyflexixanthin → an oxidized electron donor + H2O + flexixanthin
3 oxygen + 4 3-hydroxy-4-methyl-anthranilate pentapeptide lactone → 2 actinomycin D + 6 H2O
13(S)-HPOTE → H2O + (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate
(5S)-albaflavenol + NADPH + H+ + oxygen → 2 H2O + NADP+ + albaflavenone
butane + NADH + H+ + oxygen → H2O + butan-1-ol + NAD+
2-oxoglutarate + H+ + oxygen + (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate → 2 CO2 + H2O + succinate + 3-[(Z)-2-isocyanoethenyl]-1H-indole
H2O + propionitrile ← propionamide
a reduced electron donor + rotenone + oxygen → an oxidized electron donor + H2O + amorphigenin
2 H+ + 3 a reduced electron donor + 3 oxygen + protoheme → 3 an oxidized electron donor + 3 H2O + Fe2+ + (Z,Z)-biliverdin-IX α + carbon monoxide
2 L-tyrosinal → H2O + (2S)-2-[(E)-[(2S)-2-amino-3-(4-hydroxyphenyl)propylidene]amino]-3-(4-hydroxyphenyl)propanal + H+
(Z)-3-peroxyaminoacrylate + a reduced electron donor → an oxidized electron donor + H2O + aminoacrylate + H+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + β-dihydromenaquinone-9 + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + ω-hydroxy-β-dihydromenaquinone-9
4 an oxidized electron donor + 2-amino-3-[(2,5-dihydroxyphenyl)sulfanyl]propanoate + L-cysteine → 4 a reduced electron donor + H2O + L-firefly luciferin + H+ + CO2
a reduced electron donor + oxygen + γ-coniceine → an oxidized electron donor + H2O + conhydrinone
H2O + staphylopine + NADP+ ← (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + NADPH + pyruvate + H+
2 H2O + 2 cob(II)alamin + NAD+ + H+ ← 2 aquacobalamin + NADH
a reduced electron donor + 7-chloro-L-tryptophan + oxygen → 2 H2O + an oxidized electron donor + monodechloroaminopyrrolnitrin + CO2
N-methylaminobutanal → H2O + N-methyl-Δ1-pyrrolinium cation
a reduced electron donor + chlorate → an oxidized electron donor + H2O + H+ + chlorite
9'-cis-neurosporene + a reduced electron donor + oxygen → 2 H2O + an oxidized electron donor + 7',9'-cis-lycopene
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + calcidiol → 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + calcitriol
4α-hydroxymethyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)H + H+ + oxygen → 2 H2O + 4α-formyl-4β-methyl-5α-cholesta-8,24-dien-3β-ol + NAD(P)+
(2S)-pinocembrin + 2-oxoglutarate + oxygen → H2O + succinate + CO2 + chrysin
3 NADPH + 4 H+ + oxygen + 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate → 3 NADP+ + 5 H2O + UWM6 + CO2
antheraxanthin + NAD(P)H + H+ + oxygen → violaxanthin + H2O + NAD(P)+
dammarenediol II + Reduced NADPH-hemoprotein reductase + oxygen → (20S)-protopanaxadiol + Oxidized NADPH-hemoprotein reductase + H2O
(20S)-protopanaxadiol + Reduced NADPH-hemoprotein reductase + oxygen → protopanaxatriol + Oxidized NADPH-hemoprotein reductase + H2O
oxygen + indoxyl + 2-hydroxyindole → 2 H2O + Indirubin
NADPH + H+ + oxygen + indole → H2O + NADP+ + indoxyl
NADPH + H+ + oxygen + indole → H2O + NADP+ + 2-hydroxyindole
β-amyrin + 3 Reduced NADPH-hemoprotein reductase + 3 oxygen → oleanolate + 3 Oxidized NADPH-hemoprotein reductase + 4 H2O + H+
betulinic aldehyde + Reduced NADPH-hemoprotein reductase + oxygen → betulinate + Oxidized NADPH-hemoprotein reductase + H2O + H+
lupeol + Reduced NADPH-hemoprotein reductase + oxygen → betulin + Oxidized NADPH-hemoprotein reductase + H2O
betulin + Reduced NADPH-hemoprotein reductase + oxygen → betulinic aldehyde + Reduced NADPH-hemoprotein reductase + 2 H2O
diuron + NAD(P)H + oxygen + H+ → N'-(3,4-dichlorophenyl)-N-methylurea + formaldehyde + NAD(P)+ + H2O
(Z)-3-methylbutanal oxime → isovaleronitrile + H2O
7α,12α-dihydroxy-3-oxochol-4-enoate → 12-α-hydroxy-3 oxochola-4,6-dienoate + H2O
acetyl-CoA + 4 malonyl-CoA + 5 NADPH + 9 H+ → 7-methylmellein + 5 coenzyme A + 3 CO2 + 4 H2O + 5 NADP+
prochaxamycin → 3-demethylchaxamycin B + H2O
chlorotoluron + NAD(P)H + oxygen + H+ → N'-(3-chloro-4-methylphenyl)-N-methylurea + formaldehyde + NAD(P)+ + H2O
cholesterol + NADPH + H+ + oxygen → (22R)-hydroxycholesterol + NADP+ + H2O
palmitoyl-CoA + NADPH + oxygen + H+ → palmitoleoyl-CoA + NADP+ + 2 H2O
stearoyl-CoA + NADPH + oxygen + H+ → oleoyl-CoA + NADP+ + 2 H2O
3-tyramine + an oxidized unknown electron carrier + H2O ← dopamine + a reduced unknown two electron carrier
7-methylmellein + 3 oxygen + 3 NADPH + 2 H+ → 7-carboxymellein + 4 H2O + 3 NADP+
8-methylnonanoate + vanillylamine → dihydrocapsaicin + H2O
ferroheme o → ferroheme oT + H2O
(1S)-1-[(2S)-2-amino-4-methylpentanamido]ethyl(methoxy)phosphinate + 2-oxoglutarate + oxygen → 1-[(2S)-2-amino-4-methylpentanamido]ethenyl(methoxy)phosphinate + succinate + CO2 + H2O
4-aminobenzoate + 2 oxygen + a reduced unknown two electron carrier → 4-nitrobenzoate + 2 H2O + an oxidized unknown electron carrier
aloesone + D-glucopyranose → aloesin + H2O + H+
indole + oxygen + NADH + H+ → indoxyl + H2O + NAD+
D-ribose + glycine → norfuraneol + 2 H2O + glycine
2 oxygen + Latia luciferin + a reduced unknown two electron carrier → Latia oxyluciferin + formate + CO2 + H2O + an oxidized unknown electron carrier + H+ + hν
(5S)-HPETE + a reduced unknown two electron carrier → (5S)-hydroxyarachidonate + H2O + an oxidized unknown electron carrier
2,6-dichlorohydroquinone + oxygen + FADH2 → 2-chloro-6-hydroxy-1,4-benzoquinone + H2O + chloride + FAD + H+
NADPH + H+ + 3-hexaprenyl-4-hydroxybenzoate + oxygen → 3-all trans-hexaprenyl-4,5-dihydroxybenzoate + H2O + NADP+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 3-hexaprenyl-4-hydroxybenzoate + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 3-all trans-hexaprenyl-4,5-dihydroxybenzoate + H2O
7-carboxy-7-deazaguanine + ammonium + ATP → H2O + preQ0 + H+ + phosphate + ADP
L-ascorbate + 1-aminocyclopropane-1-carboxylate + H+ + oxygen → 2 H2O + L-dehydro-ascorbate + ethene + hydrogen cyanide + CO2
(3R)-3-hydroxytriacontanoyl-CoA → trans-triaconta-2-enoyl-CoA + H2O
NADPH + H+ + pentachlorophenol + oxygen → H2O + 2,3,5,6-tetrachloro-1,4-benzoquinone + NADP+ + chloride
2 oxygen + 4 a reduced ferredoxin [iron-sulfur] cluster + 4 H+ + 2-oxospirilloxanthin → 3 H2O + 4 an oxidized ferredoxin [iron-sulfur] cluster + 2,2'-dioxospirilloxanthin
H2O + NAD+ + ammonium ← 2 H+ + hydroxylamine + NADH
NADH + resorcinol + H+ + oxygen → H2O + NAD+ + hydroxyquinol
4-hydroxybutanoyl-CoA → vinylacetyl-CoA + H2O
4 Cu2+ + oxygen + 4 NADH → 4 Cu+ + 2 H2O + 4 NAD+
oleanolate + Reduced NADPH-hemoprotein reductase + oxygen → cochalate + Oxidized NADPH-hemoprotein reductase + H2O
β-amyrin + Reduced NADPH-hemoprotein reductase + oxygen → maniladiol + Oxidized NADPH-hemoprotein reductase + H2O
maniladiol + Reduced NADPH-hemoprotein reductase + oxygen → 12,13β-epoxy-16β-hydroxy-β-amyrin + Oxidized NADPH-hemoprotein reductase + H2O
oxygen + 2 L-dopa → 2 dopaquinone + 2 H2O
2 a reduced electron donor + 2 oxygen + 3'-hydroxyechinenone → 2 an oxidized electron donor + 3 H2O + adonirubin
WO2-molybdopterin cofactor + molybdopterin + H+ → bis(tungstenpterin) cofactor + H2O
4 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonate) + oxygen + 4 H+ → 4 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonate) radical cation + 2 H2O
(6E)-9-methyldec-6-enoate + vanillylamine → homocapsaicin + H2O
(2R)-homocitrate → H2O + cis-homoaconitate
2-hexaprenyl-6-methoxyphenol + oxygen → 2-hexaprenyl-6-methoxy-1,4-benzoquinone + H2O
ADP + 3 H+ + phosphate → ATP + 2 H+ + H2O
4-diphospho-1D-myo-inositol pentakisphosphate + ATP + 2 H+ → 4,5-bis(diphospho)-1D-myo-inositol tetrakisphosphate + ADP + H2O
6-diphospho-1D-myo-inositol pentakisphosphate + ATP + 2 H+ → 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + ADP + H2O
N-(tetracosanoyl)-sphinganine + H+ + NADPH + oxygen → N-(2-hydroxytetracosanoyl)-sphinganine + H2O + NADP+
N-(tetracosanoyl)-sphinganine + H+ + NADPH + oxygen → N-(lignoceroyl)-phytosphingosine + H2O + NADP+
H+ + NADPH + oxygen + zymosterol intermediate 1a → 2 H2O + NADP+ + zymosterol intermediate 1b
H+ + NADPH + oxygen + zymosterol intermediate 1b → H2O + NADP+ + zymosterol intermediate 1c
ceramide-1 (C26) + H+ + NADPH + oxygen → N-(hexacosanoyl)-phytosphingosine + H2O + NADP+
ceramide-1 (C26) + H+ + NADPH + oxygen → ceramide-2' (C26) + H2O + NADP+
N-(lignoceroyl)-phytosphingosine + H+ + NADPH + oxygen → N-(2-hydroxytetracosanoyl)-phytosphingosine + H2O + NADP+
acetyl-CoA + 24 H+ + 8 malonyl-CoA + 16 NADPH → 8 CO2 + 8 coenzyme A + 8 H2O + 16 NADP+ + stearoyl-CoA
4α-methyl-5α-cholesta-8,24-dien-3β-ol + H+ + NADPH + oxygen → H2O + NADP+ + zymosterol intermediate 1a
14-demethyllanosterol + 3 H+ + 3 NADPH + 3 oxygen → 4α-carboxy-4β-methyl-5α-cholesta-8,24-dien-3β-ol + 4 H2O + 3 NADP+
N-(hexacosanoyl)-phytosphingosine + H+ + NADPH + oxygen → N-(2-hydroxyhexacosanoyl)-phytosphingosine + H2O + NADP+
N-(2-hydroxytetracosanoyl)-phytosphingosine + H+ + NADPH + oxygen → ceramide-4 (C24) + H2O + NADP+
N-(2-hydroxyhexacosanoyl)-phytosphingosine + H+ + NADPH + oxygen → ceramide-4 (C26) + H2O + NADP+
2 H+ + lanosterol + 3 NADPH + 3 oxygen → 4,4-dimethyl-5-α-cholesta-8,14,24-trien-3-β-ol + formate + 4 H2O + 3 NADP+
ATP + 5 H+ + D-myo-inositol 1,3,4,5,6-pentakisphosphate + 2 phosphate → 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + ADP + 2 H2O
2 reduced c-type cytochrome + hydrogen peroxide → 2 oxidized c-type cytochrome + 2 H2O
heme o + NADH + oxygen → H2O + heme a + NAD+
hydrogen peroxide + Thioredoxin → 2 H2O + thioredoxin disulfide
H+ + NADPH + oxygen + D-erythro-sphinganine → H2O + NADP+ + phytosphingosine
2-hexaprenyl-6-methoxy-3-methyl-1,4-benzoquinone + H+ + NADH + oxygen → 3-demethylubiquinone-6 + H2O + NAD+
ADP + Thioredoxin → dADP + H2O + thioredoxin disulfide
CDP + Thioredoxin → dCDP + H2O + thioredoxin disulfide
GDP + Thioredoxin → dGDP + H2O + thioredoxin disulfide
hydrogen peroxide + Thioredoxin → 2 H2O + thioredoxin disulfide
GDP + Thioredoxin → dGDP + H2O + thioredoxin disulfide
acetyl-CoA + 21 H+ + 7 malonyl-CoA + 14 NADPH → 7 CO2 + 7 coenzyme A + 7 H2O + 14 NADP+ + palmitoyl-CoA
H+ + NADH + oxygen + squalene → (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O + NAD+
H+ + palmitoyl-CoA + oxygen + NADH → 2 H2O + palmitoleoyl-CoA + NAD+
H+ + stearoyl-CoA + oxygen + NADH → 2 H2O + NAD+ + oleoyl-CoA
H+ + oxygen + NADH + oleoyl-CoA → 2 H2O + NAD+ + linoleoyl-CoA
H+ + NADPH + oxygen + hexadecane → H2O + NADP+ + 1-hexadecanol
H+ + NADPH + oxygen + dodecane → H2O + NADP+ + 1-dodecanol
H+ + NADPH + oxygen + decane → H2O + NADP+ + decan-1-ol
UDP + Thioredoxin → dUDP + H2O + thioredoxin disulfide
UDP + Thioredoxin → dUDP + H2O + thioredoxin disulfide
(+)-nootkatol + Reduced NADPH-hemoprotein reductase + oxygen → (+)-nootkatone + Oxidized NADPH-hemoprotein reductase + H2O
(+)-valencene + Reduced NADPH-hemoprotein reductase + oxygen → (+)-nootkatol + Oxidized NADPH-hemoprotein reductase + H2O
2 a reduced electron donor + 2 oxygen + β-carotene → 2 an oxidized electron donor + 3 H2O + echinenone
trans-5-O-(4-coumaroyl)-D-quinate + NADPH + H+ + oxygen ↔ H2O + NADP+ + trans-5-O-caffeoyl-D-quinate
L-homocysteine + L-serine ↔ H2O + L-cystathionine
campesterol + NADPH + H+ + oxygen ↔ H2O + (22α)-hydroxy-campesterol + NADP+
(S)-N-methylcoclaurine + NADPH + H+ + oxygen ↔ H2O + 3'-hydroxy-N-methyl-(S)-coclaurine + NADP+
H2O + 3-phosphonopyruvate ↔ pyruvate + H+ + phosphate
(2Z,4E)-2-amino-5-methyl-muconate semialdehyde ↔ 5-methyl-picolinate + H2O
H2O + 7,8-dihydro-8-oxoguanine + H+ ↔ urate + ammonium
2-hydroxy-4-oxobutane-1,2,4-tricarboxylate ↔ H2O + (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate
aldehydo-L-galactonate + H+ ↔ L-galactono-1,4-lactone + H2O
H2O + blasticidin S + H+ ↔ deaminohydroxyblasticidin S + ammonium
H2O + ATP ↔ H+ + phosphate + ADP
H2O + carbonyl sulfide ↔ H+ + monothiocarbonate
2-oxoglutarate + L,L-diaminopimelate ↔ H2O + (S)-2,3,4,5-tetrahydrodipicolinate + H+ + L-glutamate
H2O + 1-heptanal ↔ hexane + formate + H+
H2O + L-arginine + ATP ↔ L-arginine + phosphate + ADP
an oxidized electron donor + H2O + arsenite ↔ a reduced electron donor + H+ + arsenate
2 an oxidized electron donor + H2O + 2,4-xylenol ↔ 2 a reduced electron donor + 4-hydroxy-3-methylbenzaldehyde
FAD + H2O + H+ + deoxycholate ↔ FADH2 + cholate
H2O + VAI-1-2 ↔ octanoate + L-homoserine lactone
H2O + L-glutamate + ATP ↔ L-glutamate + phosphate + ADP
2,3-epoxy-2,3-dihydrobenzoyl-CoA ↔ H2O + 6-hydroxy-3-hexenoyl-CoA + CO2
H2O + butachlor ↔ propan-1-ol + alachlor
L-tartrate ↔ H2O + oxaloacetate
(3R)-3-hydroxybutanoyl-CoA ↔ H2O + crotonyl-CoA
H2O + P1,P6-bis(5'-adenosyl) hexaphosphate ↔ 2 H+ + 2 ATP
4-coumaroyl-3',4'-dihydroxyphenyllactate + NADPH + H+ + oxygen ↔ H2O + rosmarinate + NADP+
H2O + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate ↔ H+ + phosphate + 1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate
H2O + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate ↔ H+ + phosphate + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate
castasterone + NADPH + H+ + oxygen ↔ H2O + brassinolide + NADP+
H2O + NAD+ ↔ nicotinamide + H+ + ADP-D-ribose
2 H+ + 6-deoxotyphasterol + oxygen ↔ H2O + 6-deoxocastasterone
H2O + adenosine 5'-phosphoramidate ↔ ammonium + AMP
H2O + streptothricin F ↔ streptothricin F acid
2-phospho-D-glycerate ↔ phosphoenolpyruvate + H2O
H2O + 5,6-dihydrothymine ↔ H+ + 3-(carbamoylamino)-2-methylpropanoate
trans-5-O-(4-coumaroyl)shikimate + NADPH + H+ + oxygen ↔ H2O + NADP+ + 5-O-caffeoylshikimate
H2O + β-isomaltose ↔ D-Glucose + α-D-glucopyranose
H2O + (3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate + H+ ↔ L-4-hydroxyglutamate semialdehyde
D-glucaro-1,4-lactone + H2O ↔ H+ + D-glucarate
H2O + 3-aminopropanal + NAD+ ↔ 2 H+ + β-alanine + NADH
H2O + 2-oxopent-4-enoate ↔ (S)-4-hydroxy-2-oxopentanoate
2 H2O + 1-piperideine 6-carboxylate + NAD+ ↔ NADH + L-2-aminoadipate + H+
H2O + 2,6-dichlorohydroquinone ↔ 6-chlorohydroxyquinol + chloride
2 Fe3+ + H2O + sulfite ↔ 2 Fe2+ + 2 H+ + sulfate
an oxidized electron donor + H2O + quinoline-4-carboxylate ↔ a reduced electron donor + 2-oxo-1,2-dihydroquinoline-4-carboxylate
2 NADH + 2 H+ + 2 oxygen + canthaxanthin ↔ 2 H2O + 2 NAD+ + 2,2'-dihydroxycanthaxanthin
2 FMNH2 + 2 oxygen + EDTA ↔ 2 FMN + 2 H2O + 2 glyoxylate + 2 H+ + ethylenediamine-N,N'-diacetate
an oxidized electron donor + H2O + quinolin-6-ol ↔ 6-hydroxyquinolin-2(1H)-one + a reduced electron donor
H2O + benzoylagmatine ↔ agmatine + benzoate
(R)-2-hydroxyglutaryl-CoA ↔ 4 H+ + H2O + (E)-glutaconyl-CoA
2 NADH + 2 H+ + 2 oxygen + adonixanthin ↔ 2 H2O + 2 NAD+ + 2,3,2',3'-tetrahydroxy-β,β-caroten-4-one
H2O + N6-(Δ2-isopentenyl)-adenosine 5'-triphosphate ↔ 2 H+ + N6-(Δ2-isopentenyl)-adenosine 5'-diphosphate + phosphate
H2O + dimethylsulfonio-2-hydroxybutanoate ↔ 4 H+ + dimethylsulfoniopropanoate + CO2
H2O + biocytin ↔ biotin + L-lysine
H2O + lauroyl-CoA + oxaloacetate ↔ coenzyme A + H+ + (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate
H2O + NAD(P)+ + L-glutamate ↔ NAD(P)H + 2-oxoglutarate + H+ + ammonium
12 H+ + 4 (R)-methylmalonyl-CoA + 8 NADPH + icosanoyl-CoA ↔ 4 coenzyme A + 4 H2O + 4 CO2 + 8 NADP+ + C32 mycocerosyl-CoA
H2O + acetyl-CoA + trans-homoaconitate ↔ coenzyme A + pentane-1,3,4,5-tetracarboxylate + H+
2 ATP + H2O + L-glutamine + hydrogencarbonate ↔ 2 H+ + 2 ADP + carbamoyl phosphate + L-glutamate + phosphate
(S)-2-amino-6-oxohexanoate ↔ H2O + 1-piperideine 6-carboxylate + H+
H2O + 2-trans,6-cis-tridecadienoyl-CoA ↔ (3R)-hydroxy, 6-cis-tridecenoyl-CoA
NADPH + oxygen + gibberellin A12-aldehyde ↔ H2O + NADP+ + gibberellin A12
an oxidized electron donor + H2O + S-sulfo-L-cysteine + glutathione ↔ a reduced electron donor + H+ + (glutathion-S-yl)-L-cysteine + sulfate
(2S)-naringenin + NADPH + oxygen ↔ H2O + NADP+ + (2S)-eriodictyol
H2O + IMP ↔ 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide
1,5-anhydro-D-fructose ↔ H2O + microthecin
H2O + L-galactono-1,5-lactone ↔ aldehydo-L-galactonate + H+
2 2,6-dimethoxyphenol + oxygen ↔ 2 H2O + 3,3',5,5'-tetramethoxydiphenoquinone
H2O + 5,6-dihydrouracil ↔ H+ + 3-ureidopropanoate
H2O + lauroyl-CoA + 2-oxoglutarate ↔ coenzyme A + H+ + 3-hydroxytetradecane-1,3,4-tricarboxylate
4-coumaroyl-4'-hydroxyphenyllactate + NADPH + H+ + oxygen ↔ H2O + 4-coumaroyl-3',4'-dihydroxyphenyllactate + NADP+
14 NADPH + 21 H+ + 7 (R)-methylmalonyl-CoA + palmitoyl-CoA ↔ 14 NADP+ + 7 coenzyme A + 7 H2O + 7 CO2 + C37-phthioceranyl-CoA
NADPH + genistein + oxygen ↔ H2O + 2'-hydroxygenistein + NADP+
phosphate + phytosphingosine ↔ H2O + phytosphingosine 1-phosphate
2 H+ + hexane-6-ol-1,3,4,6-tetracarboxylate ↔ H2O + hexane-1,3,4,6-tetracarboxylate
ADP-α-D-glucose + H2O ↔ 2 H+ + AMP + α-D-glucopyranose 1-phosphate
H2O + L-kynurenine ↔ anthranilate + H+ + L-alanine
an oxidized electron donor + H2O + (25R)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA ↔ a reduced electron donor + (24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA
melibiose + H2O ↔ α-D-galactopyranose + β-D-glucopyranose
6-(hydroxymethyl)-7,8-dihydropterin + 4-aminobenzoate ↔ 7,8-dihydropteroate + H2O
an oxidized electron donor + H2O + 4-methylquinoline ↔ 4-methylquinolin-2(1H)-one + a reduced electron donor
NAD(P)H + 5-guanidino-2-oxopentanoate + H+ + ammonium ↔ H2O + NAD(P)+ + L-arginine
NADPH + sophoradiol + H+ + oxygen ↔ H2O + soyasapogenol B + NADP+
3 N-hydroxy-N-succinylcadaverine + ATP ↔ H2O + desferrioxamine G1 + H+ + phosphate + ADP
10 malonyl-CoA + 9 H+ ↔ 10 coenzyme A + 10 CO2 + 2 H2O + tetracenomycin F2
2 H2O + carbon disulfide ↔ 2 hydrogen sulfide + CO2
H2O + (3E)-undec-2-enoyl-CoA ↔ (3R)-hydroxy-undecanoyl-CoA
typhasterol + a reduced electron donor + oxygen ↔ an oxidized electron donor + H2O + castasterone
H2O + 4-acetamidobutanoyl-CoA ↔ acetate + 4-aminobutanoyl-coA
L-asparagine ↔ H2O + 3-cyano-L-alanine + H+
2 NADPH + 5 malonyl-CoA + 6 H+ + acetyl-CoA ↔ 2 NADP+ + 3 H2O + 5 CO2 + 6 coenzyme A + 2-hydroxy-5-methyl-1-naphthoate
(S)-3-hydroxybutanoyl-CoA ↔ H2O + crotonyl-CoA
2 H+ + NADH + oxygen + phenazine-1-carboxylate ↔ H2O + phenazin-1-ol + NAD+ + CO2
(2R,3S)-3-isopropylmalate ↔ H2O + 2-isopropylmaleate
NADPH + β-amyrin + H+ + oxygen ↔ H2O + 24-hydroxy-β-amyrin + NADP+
5-(methylsulfanyl)-ribulose 1-phosphate ↔ H2O + 5-(methylsulfanyl)-2,3-dioxopentyl 1-phosphate
H2O + 2-trans, 5-cis, 7-trans-tetradecatrienoyl-CoA ↔ (3R)-hydroxy- 5-cis, 7-trans-tetradecadienoyl-CoA
glycerone phosphate + phosphoenolpyruvate + H2O ↔ methanofuran biosynththesis intermediate MF1
(S)-3-hydroxy-isobutanoyl-CoA ↔ H2O + methylacrylyl-CoA
riboflavin + H2O + H+ ↔ lumichrome + D-ribitol
H2O + D-glutamine ↔ ammonium + D-glutamate
H2O + NAD(P)+ + nitrous oxide ↔ 2 nitric oxide + NAD(P)H + H+
2 H2O + 4-chlorophenylacetonitrile ↔ 4-chlorophenylacetate + ammonium
2 NAD+ + H2O + 2-(glutathion-S-yl)-2-methylbut-3-en-1-ol ↔ 2 NADH + 3 H+ + 2-(glutathion-S-yl)-2-methylbut-3-enoate
H+ + (R)-lactate ↔ H2O + methylglyoxal
H2O + 3-hydroxy-5-phosphooxypentane-2,4-dione ↔ 3,4,4-trihydroxy-5-phosphooxypentan-2-one
2 H+ + (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-(9,11,14)-trienoate ↔ H2O + (9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate
H2O + (-)-dehydrodiconiferyl acid aldehyde ↔ (-)-dehydrodiconiferyl acid aldehyde gem-diol
4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl--D-glucosamine 6-sulfate + H2O ↔ 4-deoxy-L-threo-hex-4-enopyranuronate + N-acetyl-D-glucosamine 6-sulfate
NADPH + L-valine + oxygen ↔ H2O + N-hydroxy-L-valine + NADP+
H2O + betaine aldehyde + NAD+ ↔ 2 H+ + glycine betaine + NADH
H2O + L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine ↔ L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine + D-alanine
H2O + N-nitrosodimethylamine ↔ methylamine + formaldehyde + nitric oxide
2 L-threonine + 3 2,3-dihydroxybenzoate + norspermidine ↔ 7 H2O + vibriobactin
H2O + ATP + sn-glycerol 3-phosphate ↔ H+ + phosphate + ADP + sn-glycerol 3-phosphate
2 malonyl-CoA + H2O + hexanoyl-CoA ↔ 2 CO2 + 3 coenzyme A + OH- + triketide pyrone
H2O + NAD+ + L-serine ↔ hydroxypyruvate + NADH + H+ + ammonium
(2R,3S)-2,3-dimethylmalate ↔ H2O + dimethylmaleate
(2S)-2-isopropylmalate ↔ H2O + 2-isopropylmaleate
H2O + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA ↔ coenzyme A + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H+
chlorophyll a + oxygen ↔ H2O + chlorophyll b
(R)-malate ↔ H2O + maleate
H2O + geranyl monophosphate ↔ phosphate + geraniol
H2O + NADP+ + D-glyceraldehyde ↔ 2 H+ + (R)-glycerate + NADPH
16-α-hydroxyprogesterone ↔ H2O + 16-dehydroprogesterone
H2O + biotin amide ↔ biotin + ammonium
4 H+ + 4 malonyl-CoA ↔ 3 coenzyme A + 4 CO2 + H2O + (3,5-dihydroxyphenyl)acetyl-CoA
H2O + geranial + NAD+ ↔ 2 H+ + NADH + geranate
an oxidized electron donor + H2O + spermidine ↔ propane-1,3-diamine + a reduced electron donor + 4-aminobutanal
2 ubiquinol-8 + oxygen ↔ 2 H2O + 2 ubiquinone-8
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 71-hydroxychlorophyll a ↔ 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + chlorophyll a
H2O + NAD(P)+ + L-aspartate ↔ NAD(P)H + H+ + ammonium + oxaloacetate
H2O + betaine aldehyde + NADP+ ↔ 2 H+ + glycine betaine + NADPH
ricinoleate + ethanol ↔ H2O + lesquerolate
2 H2O + an oxidized electron donor + coenzyme A + 2-[(1R,6S)-1,6-dihydroxycyclohexa-2,4-dien-1-yl]acetyl-coA ↔ a reduced electron donor + H+ + acetyl-CoA + (3S)-hydroxyadipyl-CoA
2 H+ + 3-decaprenyl-4-hydroxybenzoate + oxygen ↔ 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + H2O
NAD(P)H + 4α-hydroxymethyl-4β-methyl-5α-cholest-7-en-3β-ol + H+ + oxygen ↔ 2 H2O + 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carbaldehyde + NAD(P)+
H2O + (R)-mandelamide ↔ (R)-mandelate + ammonium
H2O + L-glutamate + N5-methyl-L-glutamine ↔ ammonium + L-glutamate + N-methyl-L-glutamate
H2O + NADP+ + meso-diaminopimelate ↔ NADPH + L-α-amino-ε-keto-pimelate + H+ + ammonium
2 H+ + oxygen + gibberellin A12 ↔ H2O + gibberellin A53
coenzyme A + H2O ↔ 2 H+ + 4'-phosphopantetheine + adenosine 3',5'-bisphosphate
H2O + 18-oxo-oleoyl-CoA + NADP+ ↔ 2 H+ + NADPH + ω-carboxy-(9Z)-octadec-9-enoyl-CoA
H2O + 3-deacetyl-3-vinylbacteriochlorophyllide a ↔ 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a
a reduced electron donor + sarcosine + H+ + phosphate ↔ an oxidized electron donor + acetyl phosphate + H2O + methylamine
H2O + acrylonitrile ↔ acrylamide
2 H2O + 1-pyrroline + NAD+ ↔ 2 H+ + 4-aminobutanoate + NADH
H2O + (2R,4S)-2, 4-diaminopentanoate + NADP+ ↔ ammonia + (2R)-2-amino-4-oxopentanoate + NADPH
homo-UWM6 ↔ H2O + homo-prejadomycin
NAD(P)H + oxygen + magnesium-protoporphyrin IX 13-monomethyl ester ↔ H2O + NAD(P)+ + 3,8-divinyl protochlorophyllide a
H2O + 3-hydroxy-3-methyl-butanal + NAD+ ↔ 2 H+ + NADH + 3-hydroxy-3-methylbutanoate
H2O + β-D-galactopyranose + ATP ↔ β-D-galactopyranose + H+ + phosphate + ADP
(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran ↔ H2O + autoinducer 2
D-fuconate ↔ H2O + 2-dehydro-3-deoxy-D-fuconate
2 H+ + H2O + urea ↔ 2 ammonium + CO2
H2O + N-succinyl-L,L-2,6-diaminopimelate ↔ L,L-diaminopimelate + succinate
H2O + H+ + ADP ↔ ammonium + IDP
H2O + (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate ↔ H+ + succinate + (2Z)-2-hydroxypenta-2,4-dienoate
H2O + 4-aminobutanal + NADP+ ↔ 2 H+ + 4-aminobutanoate + NADPH
(2S)-homocitrate ↔ H2O + cis-homoaconitate
H2O + 5-acetamidovalerate + 2-oxoglutarate ↔ acetate + glutarate semialdehyde + L-glutamate
H2O + NAD(P)+ + 3-oxopropanoate ↔ malonate + NAD(P)H
NADPH + H+ + oxygen + gibberellin A4 ↔ H2O + NADP+ + gibberellin A1
hydrogen peroxide + hydroquinone ↔ 2 H2O + 1,4-benzoquinone
(S)-malate ↔ H2O + fumarate
H2O + UDP-α-D-sulfoquinovopyranose ↔ H+ + sulfite + UDP-α-D-glucose
(R)-4-dehydropantoate + H2O + NAD+ ↔ 2 H+ + NADH + (R)-3,3-dimethylmalate
H2O + N6-(Δ2-isopentenyl)-adenosine 5'-diphosphate ↔ N6-(Δ2-isopentenyl)-adenosine 5'-monophosphate + H+ + phosphate
NADPH + H+ + formononetin + oxygen ↔ H2O + 2-hydroxyformononetin + NADP+
H2O + L-tyrosine ↔ phenol + pyruvate + ammonium
3 oxygen + protoporphyrinogen IX ↔ 6 H2O + protoporphyrin IX
an oxidized electron donor + H2O + quinaldate ↔ kynurenate + a reduced electron donor + H+
2 H2O + GDP-β-L-galactose ↔ 2 H+ + β-L-galactopyranose + phosphate + GMP
(2R,3S)-2-methylisocitrate ↔ H2O + cis-2-methylaconitate
H2O + cytidine + H+ ↔ uridine + ammonium
H+ + (3S)-hydroxyadipyl-CoA ↔ H2O + 3,6-lactone of 3-hydroxyadinyl-CoA
NADPH + L-isoleucine + oxygen ↔ H2O + N-hydroxy-L-isoleucine + NADP+
H2O + P1,P6-bis(5'-adenosyl) hexaphosphate ↔ adenosine pentaphosphate + H+ + AMP
H2O + chlorophyllide a ↔ 3-devinyl-3-(1-hydroxyethyl)chlorophyllide a
H2O + molybdate + ATP ↔ phosphate + molybdate + ADP
H2O + NAD+ + IMP ↔ NADH + H+ + XMP
glycine betaine + H2O + ATP ↔ glycine betaine + phosphate + ADP
H2O + spermidine + ATP ↔ spermidine + phosphate + ADP
3-hydroxyisovaleryl-CoA ↔ H2O + (E)-2-methylcrotonoyl-CoA
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA ↔ H2O + (E)-2-methylcrotonoyl-CoA
menaquinol-8 + nitrate ↔ H2O + menaquinone-8 + nitrite
(S)-3-hydroxy-3-methylglutaryl-CoA ↔ H2O + 3-methylglutaconyl-CoA
H2O + H+ + L-mimosine ↔ 3-hydroxy-4h-pyrid-4-one + L-serine
H2O + (R)-pantothenate ↔ β-alanine + (R)-pantoate
5-phospho-α-D-ribose 1-diphosphate + nicotinate + H2O + ATP ↔ β-nicotinate D-ribonucleotide + diphosphate + phosphate + ADP
2 H2O + 2 ATP + a reduced electron donor + benzoyl-CoA ↔ 2 phosphate + 2 ADP + an oxidized electron donor + cyclohex-1,5-diene-1-carbonyl-CoA
3 NADP+ + H2O + magnesium-protoporphyrin IX 13-monomethyl ester ↔ 3 NADPH + 4 H+ + 3,8-divinyl protochlorophyllide a
H2O + NAD(P)+ + 2-acetamidofluorene ↔ N-hydroxy-2-acetamidofluorene + NAD(P)H + H+
H2O + NADP+ + L-valine ↔ NADPH + 3-methyl-2-oxobutanoate + H+ + ammonium
H2O + pyruvate + ATP ↔ 2 H+ + phosphoenolpyruvate + phosphate + AMP
H2O + penicillin G ↔ 6-aminopenicillanate + phenylacetate
H2O + L-arginine ↔ L-citrulline + ammonium
H2O + phosphonoacetaldehyde ↔ acetaldehyde + H+ + phosphate
H2O + L-serine O-sulfate ↔ pyruvate + H+ + ammonium + sulfate
4-O-dimethylallyl-L-tyrosine + L-serine ↔ 2 H2O + phomamide
NADPH + H+ + oxygen + (2S)-eriodictyol ↔ (2S)-dihydrotricetin + H2O + NADP+
H2O + 1,4-diguanidinobutane ↔ agmatine + urea
(3S)-hydroxyadipyl-CoA ↔ H2O + 2,3-didehydroadipyl-CoA
H2O + (2E,5E)-dodeca-2,5-dienoyl-CoA ↔ (3R)-hydroxy-5-trans-dodecenoyl-CoA
ecdysone + a reduced electron donor + oxygen ↔ an oxidized electron donor + 20-hydroxyecdysone + H2O
2 H2O + 6-oxocyclohex-1-ene-1-carbonyl-CoA ↔ 3-hydroxypimeloyl-CoA + H+
H2O + L-aspartate + oxygen ↔ ammonia + hydrogen peroxide + oxaloacetate
protoaphin aglucone + H+ ↔ xanthoaphin + H2O
H2O + 5,10-methenyltetrahydrofolate mono-L-glutamate ↔ 10-formyl-tetrahydrofolate mono-L-glutamate + H+
H2O + L-5-carboxymethylhydantoin ↔ N-carbamoyl-L-aspartate + H+
NADPH + tert-amyl alcohol + H+ + oxygen ↔ H2O + 2-methyl-butane-1,2-diol + NADP+
H2O + streptothricin D ↔ streptothricin D acid
H2O + ADP-D-ribose ↔ 2 H+ + aldehydo-D-ribose 5-phosphate + AMP
2 H2O + 3 NAD(P)+ + ammonium ↔ 3 NAD(P)H + 5 H+ + nitrite
L-serine + 5,6,7,8-tetrahydrofolate ↔ H2O + glycine + 5,10-methylenetetrahydropteroyl mono-L-glutamate
S-ribosyl-L-homocysteine + adenine ↔ H2O + S-adenosyl-L-homocysteine
3 H+ + a reduced electron donor + nitrite ↔ an oxidized electron donor + H2O + hydroxylamine
H2O + 2-trans-nonenoyl-CoA ↔ (3R)-hydroxy-nonanoyl-CoA
2 H2O + 1-piperideine 6-carboxylate + NAD(P)+ ↔ NAD(P)H + L-2-aminoadipate + H+
H2O + chloride + ATP ↔ H+ + phosphate + chloride + ADP
H2O + 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate ↔ H+ + phosphate + 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate
H2O + L-tryptophanamide ↔ ammonium + L-tryptophan
H2O + aurachin B + NAD+ ↔ NADH + 4-hydroxy-2-methyl-3-oxo-4-farnesyl-3,4-dihydroquinoline-1-oxide + H+
H2O + 5-amino-1-(5-phospho-β-D-ribosyl)imidazole + ATP + CO2 ↔ N5-carboxyaminoimidazole ribonucleotide + phosphate + ADP
H2O + NADP+ + 10-formyl-tetrahydrofolate mono-L-glutamate ↔ NADPH + H+ + 5,6,7,8-tetrahydrofolate + CO2
2 H+ + 2-hexaprenyl-6-methoxyphenol + oxygen ↔ H2O + 2-methoxy-6-all trans-hexaprenyl-1,4-benzoquinol
2 NAD(P)+ + H2O + 4-hydroxyaminoquinoline-N-oxide ↔ 2 NAD(P)H + 2 H+ + 4-nitroquinoline-N-oxide
H2O + NAD+ + 2-formylbenzoate ↔ 2 H+ + phthalate + NADH
H2O + ferric-enterobactin complex + ATP ↔ H+ + phosphate + ferric-enterobactin complex + ADP
H2O + juvenile hormone I ↔ juvenile hormone I acid + methanol + H+
pentane + NADH + H+ + oxygen ↔ H2O + (2R)-pentan-2-ol + NAD+
H2O + (2E,6E)-farnesyl diphosphate ↔ diphosphate + (-)-α-bisabolol
H2O + 2-oxoglutarate + ATP + CO2 ↔ 2 H+ + oxalosuccinate + phosphate + ADP
H2O + glycine + 5,10-methylene-tetrahydromethanopterin ↔ tetrahydromethanopterin + L-serine
L-glutamate-5-semialdehyde ↔ H2O + H+ + (S)-1-pyrroline-5-carboxylate
H2O + S-allyl-L-cysteine + oxygen ↔ hydrogen peroxide + (+)-trans-isoalliin
NAD(P)H + 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carbaldehyde + oxygen ↔ H2O + NAD(P)+ + 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carboxylate
H2O + H+ + carbamate ↔ ammonium + hydrogencarbonate
2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + D-glyceraldehyde 3-phosphate ↔ 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 3-phospho-D-glycerate
H2O + L-proline amide ↔ ammonium + L-proline
2 NAD+ + H2O + 2-hydroxyethyl-CoM ↔ 2 NADH + 3 H+ + 2-carboxyethyl-CoM
1-chloro-4-nitrobenzene + NADPH + H+ ↔ 1-chloro-4-nitrosobenzene + H2O + NADP+
NADPH + calycosin + H+ + oxygen ↔ 2 H2O + pseudobaptigenin + NADP+
H2O + trans-2,3-dehydroadipyl-coA ↔ (3S)-hydroxyadipyl-CoA
L-threonine + hydrogencarbonate + ATP ↔ H2O + (L-threonylcarbamoyl)adenylate + diphosphate
caffeoyl-4'-hydroxyphenyllactate + NADPH + H+ + oxygen ↔ H2O + rosmarinate + NADP+
H2O + isopentenyl diphosphate + NAD(P)+ ↔ (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+
(S)-citramalate ↔ H2O + mesaconate
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + geranylgeraniol + oxygen ↔ 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + (2E,6E,10E,14E)-2,6,10,14-tetramethylhexadeca-2,6,10,14-tetraene-1,16-diol
H2O + (7R)-7-(4-carboxybutanamido)cephalosporanate ↔ (7R)-7 aminocephalosporanate + glutarate
β-carotene 15,15' epoxide + H2O ↔ 15,15'-dihydroxy-β-carotene
(15R)-HPETE ↔ H2O + 15-KETE
D-xylonate ↔ H2O + 2-dehydro-3-deoxy-D-pentonate
H2O + puberulonate ↔ puberulate + H+ + CO2
2 H2O + 2 cob(II)alamin + NADP+ + H+ ↔ 2 aquacobalamin + NADPH
H2O + glycine + NAD+ ↔ NADH + glyoxylate + H+ + ammonium
H2O + L-aspartate + ATP ↔ L-aspartate + phosphate + ADP
2 H+ + 1'-hydroxy-γ-carotene + a reduced ferredoxin [iron-sulfur] cluster + oxygen ↔ plectaniaxanthin + an oxidized ferredoxin [iron-sulfur] cluster + H2O
H2O + sulfate + ATP ↔ H+ + phosphate + sulfate + ADP
H2O + (2E)-oct-2-enoyl-CoA ↔ (S)-3-hydroxyoctanoyl-CoA
H2O + acetylenedicarboxylate + H+ ↔ pyruvate + CO2
an oxidized ferredoxin [iron-sulfur] cluster + H2O + carbon monoxide ↔ a reduced ferredoxin [iron-sulfur] cluster + H+ + CO2
L-ascorbate + hydrogen peroxide + H+ ↔ 2 H2O + L-dehydro-ascorbate
betaine aldehyde hydrate ↔ H2O + betaine aldehyde
H2O + pyrethrin I ↔ (1R)-trans-chrysanthemate + (S)-pyrethrolone + H+
(E)-2,4-dihydroxycinnamate + H+ ↔ H2O + umbelliferone
cathasterone + a reduced electron donor + oxygen ↔ an oxidized electron donor + H2O + teasterone
5-α-ergosta-7, 22-diene-3-β,5-diol ↔ ergosterol + H2O
H2O + N8-acetylspermidine ↔ acetate + spermidine
3 NADPH + 5 malonyl-CoA + 7 H+ + acetyl-CoA ↔ 3 NADP+ + 4 H2O + 5 CO2 + 6 coenzyme A + 5-methyl-1-naphthoate
H2O + 5,10-methenyltetrahydromethanopterin ↔ 5-formyl-tetrahydromethanopterin + H+
H2O + ononin ↔ formononetin + β-D-glucopyranose
FAD + H2O + H+ + lithocholate ↔ FADH2 + chenodeoxycholate
H2O + deethylatrazine ↔ H+ + 2-hydroxy-4-isopropylamino-6-amino-s-triazine + chloride
butane + NADH + H+ + oxygen ↔ H2O + (2R)-butan-2-ol + NAD+
H2O + (S)-dihydroorotate ↔ N-carbamoyl-L-aspartate + H+
NAD(P)H + 4,4-dimethyl-5α-cholest-7-en-3β-ol + H+ + oxygen ↔ H2O + 4α-hydroxymethyl-4β-methyl-5α-cholest-7-en-3β-ol + NAD(P)+
H2O + ATP + D-methionine ↔ phosphate + ADP + D-methionine
N-acetyl-muramoyl-(L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine) + H2O ↔ N-acetyl-muramoyl-(L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine) + D-alanine
H2O ↔ 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate
H2O + VAI-1 ↔ 3-oxohexanoate + L-homoserine lactone
xanthine + H2O + NAD+ ↔ NADH + urate + H+
H2O + trans-homoaconitate ↔ (2S)-homocitrate
2 a reduced electron donor + H+ + nitrite ↔ 2 an oxidized electron donor + H2O + hydroxylamine
H2O + H+ + urethan ↔ ethanol + ammonium + CO2
H2O + ADP-D-ribose ↔ 2 H+ + α-D-ribose-1-phosphate + AMP
3-hydroxypropanoyl-CoA ↔ H2O + acryloyl-CoA
H2O + D-phenylhydantoin ↔ N-carbamoyl-D-phenylglycine
H2O + 3-cyanopyridine ↔ nicotinamide
H2O + 3-guanidinopropanoate ↔ β-alanine + urea
H2O + NAD(P)+ + L-tryptophan ↔ NAD(P)H + H+ + ammonium + (indol-3-yl)pyruvate
anhydrorhodovibrin + H2O ↔ rhodovibrin
2 cyclohexane-1-carboxylate + coenzyme A + H2O + ATP ↔ 2 cyclohexane-1-carbonyl-CoA + 2 H+ + 2 phosphate + AMP
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + (2E,6E)-farnesol + oxygen ↔ 2 an oxidized ferredoxin [iron-sulfur] cluster + (2E,6E,10E)-2,6,10-trimethyldodeca-2,6,10-triene-1,12-diol + H2O
H2O + 2-hydroxy-2-methyl-butanal + NAD+ ↔ 2 H+ + NADH + 2-hydroxy-2-methylbutanoate
H2O + NAD+ + L-glutamate ↔ NADH + 2-oxoglutarate + H+ + ammonium
2 formaldehyde + H2O ↔ formate + methanol + H+
H2O + 1-stearoyl-2-palmitoyl-sn-glycerol 3-phosphate ↔ 1-stearoyl-2-palmitoyl-glycerol + phosphate
(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O ↔ (-)-geosmin + acetone
2 H+ + 3-nonaprenyl-4-hydroxybenzoate + oxygen ↔ 3,4-dihydroxy-5-all-trans-nonaprenylbenzoate + H2O
H2O + (indole-3-yl)acetonitrile ↔ (indol-3-yl)acetamide
N-hydroxy-L-valine + NADPH + H+ + oxygen ↔ H2O + N,N-dihydroxy-L-valine + NADP+
citrate ↔ H2O + cis-aconitate
12α-hydroxy-3-oxocholan-24-oyl-CoA + H2O ↔ coenzyme A + H+ + 3-dehydrodeoxycholate
H2O + lotaustralin ↔ 2-hydroxy-2-methylbutyronitrile + β-D-glucopyranose
prephenate + H+ ↔ H2O + 3-phenyl-2-oxopropanoate + CO2
D-galactaro-1,4-lactone + H2O ↔ H+ + D-galactarate
H2O + pyruvate + ubiquinone-9 ↔ acetate + ubiquinol-9 + CO2
H2O + 2-oxobutanoate + acetyl-CoA ↔ coenzyme A + (R)-2-Ethylmalate + H+
H2O + N(α)-benzyloxycarbonyl-L-leucine + H+ ↔ benzyl alcohol + L-leucine + CO2
15-cis-phytoene + a reduced electron donor + oxygen ↔ 2 H2O + an oxidized electron donor + 9,15,9'-tri-cis-ζ-carotene
D-tartrate ↔ H2O + oxaloacetate
7-deoxyloganin + NADPH + H+ + oxygen ↔ H2O + loganin + NADP+
hydrogen peroxide + 6-hydroxy-2-[hydroxy-(4-hydroxyphenyl)methyl]-1-benzofuran-3-one ↔ H2O + 2-[hydroperoxy(4-hydroxyphenyl)methyl]-6-hydroxy-1-benzofuran-3-one
H2O + N-acetyl-D-muramate 6-phosphate ↔ N-acetyl-D-glucosamine-6-phosphate + (R)-lactate
2 H+ + hydrogen peroxide + 6-hydroxy-2-(6-oxo-1-oxaspiro[2.5]octa-4,7-dien-2-yl)-1-benzofuran-3-one ↔ H2O + 2-[hydroperoxy(4-hydroxyphenyl)methyl]-6-hydroxy-1-benzofuran-3-one
p-(β-aminoethyl)phenoxy-methyl-2-(aminomethyl)furan + L-glutamate ↔ H2O + (4-{4-[2-(γ-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine
methanofuran biosynththesis intermediate MF2 ↔ H2O + methanofuran biosynththesis intermediate MF3
H2O + propanoyl-CoA + ATP + CO2 ↔ (S)-methylmalonyl-CoA + phosphate + ADP
a reduced ferredoxin [iron-sulfur] cluster + nitrite ↔ ammonia + an oxidized ferredoxin [iron-sulfur] cluster + H2O
2-[(5'-methylsulfanyl)pentyl]malate ↔ H2O + 2-[(2'-methylsulfanyl)pentyl]maleate
H2O + 2-[(2'-methylsulfanyl)pentyl]maleate ↔ 3-[(5'-methylsulfanyl)pentyl]malate
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + phytanate + oxygen ↔ 2 an oxidized ferredoxin [iron-sulfur] cluster + 16-hydroxyphytanate + H2O
H2O + 2-phenylacetamide ↔ phenylacetate + ammonium
NADPH + tert-amyl alcohol + H+ + oxygen ↔ H2O + 2-methyl-butan-2,3-diol + NADP+
(2S)-methylbutanenitrile + NADPH + H+ + oxygen ↔ H2O + 2-hydroxy-2-methylbutyronitrile + NADP+
H2O + hydantoin ↔ N-carbamoylglycine + H+
H2O + trans-feruloyl-CoA ↔ 4-hydroxy-3-methoxyphenyl-β-hydroxypropanoyl-CoA
H2O + N-benzoyl-D-arginine-4-nitroanilide ↔ N-benzoyl-D-arginine + 4-nitroaniline
ent-kaurenol + NADPH + H+ + oxygen ↔ 2 H2O + ent-kaurenal + NADP+
H2O + 2,3-diaminopropionate ↔ 2 ammonia + pyruvate + H+
(4-hydroxyphenyl)acetate + NADH + H+ + oxygen ↔ H2O + 3,4-dihydroxyphenylacetate + NAD+
2 H+ + NADH + trimethylamine N-oxide ↔ H2O + NAD+ + trimethylamine
H2O + 2,5-dihydroxypyridine + oxygen ↔ 2 H+ + maleamate + formate
H2O + HAI-1 ↔ (R)-3-hydroxybutanoate + L-homoserine lactone
H2O + N-benzylformamide ↔ formate + benzylamine
N6-(6-phospho-D-fructosyl)-L-lysine + H2O ↔ β-D-glucose 6-phosphate + L-lysine
N-hydroxy-L-phenylalanine + NADPH + H+ + oxygen ↔ H2O + N,N-dihydroxy-L-phenylalanine + NADP+
H2O + α-D-glucosamine 6-phosphate ↔ β-D-fructofuranose 6-phosphate + ammonium
H2O + NADP+ + L-glutamate ↔ NADPH + 2-oxoglutarate + H+ + ammonium
L-carnitine ↔ H2O + crotono-betaine
urea ↔ H2O + cyanamide
2-hydroxyferulate + H+ ↔ H2O + scopoletin
2 3-[(8Z,11E,13Z)-pentadeca-8,11,13-trien-1-yl] )catechol + oxygen ↔ H2O + 8'-(3,4-dihydroxy-5-alkenyl)phenyl-3-[9'E,11'E,13'Z-pentadecatrienyl]catechol
pseudobaptigenin + NADPH + H+ + oxygen ↔ H2O + 2'-hydroxypseudobaptigenin + NADP+
NADPH + L-phenylalanine + oxygen ↔ H2O + N-hydroxy-L-phenylalanine + NADP+
H2O + D-arginine ↔ D-ornithine + urea
an oxidized electron donor + 8-hydroxyquinoline + H2O ↔ 8-hydroxyquinolin-2(1H)-one + a reduced electron donor
(3S)-3-hydroxy-L-arginine ↔ H2O + H+ + (2S,3R)-capreo-mycidine 5
2 NAD(P)H + 2 H+ + 2 L-arginine + 2 oxygen ↔ 2 H2O + 2 NAD(P)+ + 2 Nω-hydroxy-L-arginine
(2R,3S)-β-methylmalyl-CoA ↔ H2O + 2-methylfumaryl-CoA
2 H+ + 3-hexaprenyl-4-hydroxybenzoate + oxygen ↔ 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O
FADH2 + oxygen + 7-hydroxy-3-isocyanochromen-2-one ↔ FAD + H2O + H+ + paerucumarin
(1R,2S)-homoisocitrate ↔ H2O + cis-homoaconitate
H2O + N,N-Dimethylformamide ↔ dimethylamine + formate
2 H+ + L-tryptophan + oxygen ↔ ammonia + H2O + (indol-3-yl)acetaldehyde + CO2
2-[(2'-methylsulfanyl)ethyl]malate ↔ H2O + 2-[(2'-methylsulfanyl)ethyl]maleate
H2O + 2-[(2'-methylsulfanyl)ethyl]maleate ↔ 3-[(2'-methylsulfanyl)ethyl]malate
2 H2O + 3,5-dibromo-4-hydroxybenzonitrile ↔ ammonium + 3,5-dibromo-4-hydroxybenzoate
2 NADP+ + H2O + dTDP-α-D-galactose ↔ 2 NADPH + 3 H+ + dTDP-D-galacturonate
H2O + leukotriene-D4 ↔ glycine + leukotriene-E4
ent-7α-hydroxykaur-16-en-19-oate + NADPH + H+ + oxygen ↔ 2 H2O + NADP+ + gibberellin A12-aldehyde
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + oxygen + (2E,6E)-farnesyl diphosphate ↔ 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + (2E,6E,10E)-12-hydroxy-3,7,11-trimethyldodeca-2,6,10-trien-1-yl phosphonatooxyphosphonate
H2O + 2-[(2'-methylsulfanyl)butyl]maleate ↔ 3-[(4'-methylsulfanyl)butyl]malate
H2O + pseudouridine 5'-phosphate ↔ pseudouridine + phosphate
2-[(4'-methylsulfanyl)butyl]malate ↔ H2O + 2-[(2'-methylsulfanyl)butyl]maleate
H2O + AAI-1 ↔ 3-oxooctanoate + L-homoserine lactone
D-erythrose 4-phosphate + phosphoenolpyruvate + H2O ↔ 3-deoxy-D-arabino-heptulosonate 7-phosphate + phosphate
H2O + NAD(P)+ + L-malic semialdehyde ↔ 2 H+ + NAD(P)H + (S)-malate
H2O + pentanamide ↔ pentanoate + ammonium
NADPH + β-amyrin + H+ + oxygen ↔ H2O + NADP+ + sophoradiol
NADH + 3-(3-hydroxyphenyl)propanoate + H+ + oxygen ↔ H2O + 3-(2,3-dihydroxyphenyl)propanoate + NAD+
ent-kaurenal + NADPH + oxygen ↔ ent-kaur-16-en-19-oate + H2O + NADP+
ent-kaur-16-en-19-oate + NADPH + H+ + oxygen ↔ ent-7α-hydroxykaur-16-en-19-oate + H2O + NADP+
scytalone ↔ H2O + 1,3,8-naphthalenetriol
H2O + (2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate + NAD+ ↔ NADH + pyruvate + H+ + L-norvaline
H2O + 4-carboxybenzaldehyde + NAD+ ↔ 2 H+ + terephthalate + NADH
H2O + H+ + ATP ↔ ammonium + ITP
H2O + thiamine diphosphate ↔ thiamine phosphate + H+ + phosphate
trans-2-butene + NADH + H+ + oxygen ↔ H2O + trans-2R,3R-epoxybutane + NAD+
(3R)-sophorol + NADPH + H+ ↔ H2O + NADP+ + (-)-maackiain
H2O + O-phosphoethanolamine ↔ acetaldehyde + ammonium + phosphate
2 H+ + oxygen + (indol-3-yl)acetate ↔ H2O + indole-3-glycolate
H+ + hydrogencarbonate ↔ H2O + CO2
hydrogen peroxide + veratryl alcohol ↔ 2 H2O + veratraldehyde
H2O + N-ethylammelide + H+ ↔ ethylamine + cyanuric acid
12 H+ + 4 (R)-methylmalonyl-CoA + 8 NADPH + stearoyl-CoA ↔ 4 coenzyme A + 4 H2O + 4 CO2 + 8 NADP+ + C30 mycocerosyl-CoA
2 Nω-hydroxy-L-arginine + 2 oxygen + NAD(P)H ↔ 2 H2O + 2 L-citrulline + 2 nitric oxide + NAD(P)+ + H+
(12S)-HPETE ↔ H2O + 12-KETE
H2O + pentanoyl-CoA + glyoxylate ↔ coenzyme A + 3-propylmalate + H+
NADPH + H+ + demethylsuberosin + oxygen ↔ (+)-marmesin + H2O + NADP+
(12R)-HPETE ↔ H2O + 12-KETE
2 H+ + 3-octaprenyl-4-hydroxybenzoate + oxygen ↔ 3,4-dihydroxy-5-all-trans-octaprenylbenzoate + H2O
H2O + guanidinoacetate ↔ glycine + urea
dTDP-4-dehydro-6-deoxy-α-D-glucopyranose ↔ H2O + dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose
3-dehydroquinate ↔ H2O + 3-dehydroshikimate
NAD(P)H + 4α-hydroxymethyl-4β-methyl-5α-cholest-7-en-3β-ol + H+ + oxygen ↔ H2O + 3β-hydroxy-4β-methyl-5α-cholest-7-ene-4α-carbaldehyde + NAD(P)+
H2O + α-maltose 6'-phosphate ↔ β-D-glucose 6-phosphate + β-D-glucopyranose
4-aminobutanal ↔ H2O + 1-pyrroline
H2O + NADP+ + nitrous oxide ↔ 2 nitric oxide + NADPH + H+
NADPH + oxygen + gibberellin A14-aldehyde ↔ H2O + NADP+ + gibberellin A14
N-hydroxy-L-isoleucine + NADPH + H+ + oxygen ↔ H2O + N,N-dihydroxy-L-isoleucine + NADP+
ent-kaurene + NADPH + H+ + oxygen ↔ H2O + ent-kaurenol + NADP+
H2O + cyclohexylsulfamate ↔ cyclohexylamine + sulfate
NADPH + H+ + oxygen + gibberellin A12-aldehyde ↔ H2O + NADP+ + gibberellin A14-aldehyde
NADPH + H+ + oxygen + gibberellin A7 ↔ H2O + NADP+ + gibberellin A3
(3R)-hydroxydecanoyl-CoA ↔ H2O + (2E)-dec-2-enoyl-CoA
(S)-lactoyl-CoA ↔ H2O + acryloyl-CoA
pyrazole + L-serine ↔ H2O + 3-(pyrazol-1-yl)-L-alanine
2 H+ + 6-deoxocathasterone + oxygen ↔ H2O + 6-deoxoteasterone
6-oxocyclohex-1-ene-1-carbonyl-CoA + H2O ↔ 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA
carbonic acid ↔ H2O + CO2
H2O + (+)-β-caryophyllene ↔ (+)-caryolan-1-ol
2 H+ + 3 nitrite ↔ 2 nitric oxide + H2O + nitrate
D-glutamate ↔ H2O + 5-oxo-D-proline
H2O + 2-oxoglutarate + acetyl-CoA ↔ coenzyme A + H+ + (2R)-homocitrate
campestanol + NADPH + H+ + oxygen ↔ H2O + 6-deoxocathasterone + NADP+
phosphate-ester-of-dihydrofuran ↔ H2O + 2,4-substituted-furan
(5α)-campestan-3-one + NADPH + H+ + oxygen ↔ H2O + (22S,24R)-22-hydroxy-5α-ergostan-3-one + NADP+
sporulenol ↔ H2O + tetraprenyl-β-curcumene
7-α,12-α-dihydroxy-3-oxochol-4-enoate ↔ H2O + 12-α-hydroxy-3 oxochola-4,6-dienoate
2 L-ascorbate + 2 H+ + violaxanthin ↔ 2 H2O + 2 L-dehydro-ascorbate + zeaxanthin
H2O + 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(β-hydroxyethyl)-2-methylpyridinium + H+ ↔ 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(β-hydroxyethyl)-2-methylpyridinium + ammonium
NADPH + H+ + oxygen + geraniol ↔ H2O + NADP+ + (6E)-8-hydroxygeraniol
H2O + benzaldehyde + NAD+ ↔ 2 H+ + NADH + benzoate
4-dimethylaminophenylazobenzene + H2O + NADP+ ↔ 4-(dimethylamino)phenylazoxybenzene + NADPH + H+
H2O + NADP+ + (1Z,2S)-2-methylbutanal oxime ↔ 3 H+ + (2S)-methylbutanenitrile + NADPH + oxygen
(3S)-linalool ↔ β-myrcene + H2O
H2O + umbelliferone ↔ 2 H+ + esculetin
2 H2O + 2-methylfumaryl-CoA ↔ coenzyme A + H+ + (R)-citramalate
ubiquinol-8 + nitrate ↔ H2O + ubiquinone-8 + nitrite
4-coumaroyl-4'-hydroxyphenyllactate + NADPH + H+ + oxygen ↔ H2O + caffeoyl-4'-hydroxyphenyllactate + NADP+
(8R)-HPETE ↔ H2O + 8-KETE
H2O + N-feruloylglycine ↔ glycine + ferulate
(8S)-HPETE ↔ H2O + 8-KETE
H2O + L-methionine + ATP ↔ L-methionine + phosphate + ADP
H2O + NADP+ + N-methyl-L-alanine ↔ methylamine + NADPH + pyruvate + H+
3α-hydroxy-3,5-dihydromonacolin L acid + H+ ↔ H2O + 3α-hydroxy-3,5-dihydromonacolin L lactone
H2O + bis(p-nitrophenyl) phosphate ↔ 2 H+ + 4-nitrophenol + 4-nitrophenyl phosphate
3 (R)-methylmalonyl-CoA + 6 NADPH + 9 H+ + icosanoyl-CoA ↔ 3 coenzyme A + 3 H2O + 3 CO2 + 6 NADP+ + C29-mycolipanoyl-CoA
H2O + (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate ↔ pyruvate + 2-formylbenzoate
NADPH + H+ + formononetin + oxygen ↔ H2O + calycosin + NADP+
2-[(7'-methylsulfanyl)heptyl]malate ↔ H2O + 2-[(2'-methylsulfanyl)heptyl]maleate
H2O + 2-[(2'-methylsulfanyl)heptyl]maleate ↔ 3-[(7'-methylsulfanyl)heptyl]malate
tetrahydrosarcinapterin + methanol ↔ 5-methyl-tetrahydrosarcinapterin + H2O
H2O + 2-[(2'-methylsulfanyl)hexyl]maleate ↔ 3-[(6'-methylsulfanyl)hexyl]malate
2-[(6'-methylsulfanyl)hexyl]malate ↔ H2O + 2-[(2'-methylsulfanyl)hexyl]maleate
H2O + H+ + N-benzyloxycarbonylglycine ↔ glycine + benzyl alcohol + CO2
H2O + 5,10-methylenetetrahydropteroyl mono-L-glutamate + dCMP ↔ 2'-deoxy-5-hydroxymethylcytidine 5'-phosphate + 5,6,7,8-tetrahydrofolate
H2O + glutathionylspermidine ↔ spermidine + glutathione
NADPH + acetone + H+ + oxygen ↔ hydroxyacetone + H2O + NADP+
2 H2O + coenzyme A + 2-[(1R,6S)-1,6-dihydroxycyclohexa-2,4-dien-1-yl]acetyl-coA ↔ 3 H+ + acetyl-CoA + (3S)-hydroxyadipyl-CoA
an oxidized electron donor + H2O + quinolin-7-ol ↔ 7-hydroxyquinolin-2(1H)-one + a reduced electron donor
H2O + L-phenylalanine + ATP ↔ H+ + diphosphate + AMP + D-phenylalanine
agmatine + cytidine ↔ H2O + agmatidine
2 an oxidized ferredoxin [iron-sulfur] cluster + tetrahydrosarcinapterin + H2O + acetyl-CoA ↔ 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + coenzyme A + 5-methyl-tetrahydrosarcinapterin + CO2
H2O + D-cysteine ↔ pyruvate + ammonium + hydrogen sulfide
2 H2O + NAD(P)+ + (S)-1-pyrroline-5-carboxylate ↔ NAD(P)H + H+ + L-glutamate
2 α-D-glucopyranose 1-phosphate + H2O ↔ 2 phosphate + maltose
H2O + N-acetyl-α-D-glucosamine + NAD+ ↔ 2 H+ + N-acetyl-D-glucosaminate + NADH
5-phospho-β-D-ribosylamine + L-glutamate + diphosphate ↔ 5-phospho-α-D-ribose 1-diphosphate + H2O + L-glutamine
monoanhydrobacterioruberin ↔ bisanhydrobacterioruberin + H2O
H2O + L-saccharopine + NADP+ ↔ NADPH + 2-oxoglutarate + H+ + L-lysine
campest-4-en-3-one + NADPH + H+ + oxygen ↔ H2O + (22α)-hydroxy-campest-4-en-3-one + NADP+
3 H2O + an oxidized electron donor + hydrogen sulfide ↔ 6 H+ + a reduced electron donor + sulfite
D-galactarate ↔ H2O + (2S,3R)-2,3-dihydroxy-5-oxohexanedioate
H2O + unsaturated gellan tetrasaccharide ↔ (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + β-D-Glcp-(1→4)-α-L-Rhap-(1→3)-D-Glcp
H2O + (5R)-5-phosphooxy-L-lysine ↔ (S)-2-amino-6-oxohexanoate + ammonium + phosphate
an oxidized electron donor + H2O + quinoline ↔ quinolin-2(1H)-one + a reduced electron donor
H2O + an oxidized acceptor + indole-3-glyoxal ↔ a reduced electron donor + indole-3-glyoxylate
2 H+ + 2 3-phospho-D-glycerate ↔ H2O + CO2 + D-ribulose-1,5-bisphosphate
3 NAD(P)+ + H2O + ammonium hydroxide ↔ 3 NAD(P)H + nitrite
H2O + NAD(P)+ + D-glyceraldehyde 3-phosphate ↔ 2 H+ + NAD(P)H + 3-phospho-D-glycerate
H2O + maleimide ↔ maleamate + H+
H2O + 1D-myo-inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate ↔ 2 H+ + phosphate + phytate
L-ascorbate + H2O ↔ 2-keto-L-gulonate
H2O + N-formimino-L-aspartate ↔ ammonium + N-formyl-L-aspartate
H2O + (+)-dehydrodiconiferyl acid aldehyde ↔ (+)-dehydrodiconiferyl acid gem-diol
H2O + (2E)-2-hydroxypenta-2,4-dienoate ↔ (S)-4-hydroxy-2-oxopentanoate
2 H2O + 2-hydroxy-2-methylpropanenitrile ↔ 2-hydroxy-2-methylpropanoate + ammonium
2-dehydro-D-glucopyranose ↔ H2O + cortalcerone
H2O + 2-trans-6-trans-tridecadienoyl-CoA ↔ (3R)-hydroxy, 6-trans-tridecenoyl-CoA
H2O + acetoacetyl-CoA + acetyl-CoA ↔ coenzyme A + H+ + (S)-3-hydroxy-3-methylglutaryl-CoA
6-deoxotyphasterol + oxygen ↔ H2O + typhasterol
6-oxocampestanol + NADPH + H+ + oxygen ↔ H2O + cathasterone + NADP+
2 H+ + oxygen + (indol-3-yl)acetaldehyde ↔ H2O + indole-3-glycol aldehyde
an oxidized electron donor + H2O + 8-choloroquinoline ↔ 8-chloroquinolin-2(1H)-one + a reduced electron donor
H2O + oxidized dithiothreitol + 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone ↔ vitamin K 2,3-epoxide + L-dithiothreitol
2-oxoglutarate + putrescine ↔ H2O + 1-pyrroline + L-glutamate
H2O + trithionate ↔ H+ + sulfate + thiosulfate
2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + carbon monoxide ↔ 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + CO2
NADPH + H+ + tirandamycin C + oxygen ↔ H2O + NADP+ + tirandamycin F
H2O + carbon monoxide ↔ H2 + CO2
2 H2O + 2 ATP + a reduced electron donor + 4-methylbenzoyl-CoA ↔ 2 H+ + 2 phosphate + 2 ADP + an oxidized electron donor + 4-methylcyclohex-1,5-diene-1-carbonyl-CoA
H2O + aldehydo-D-ribose + NADP+ ↔ 2 H+ + D-ribonate + NADPH
H2O + propanoyl-CoA + oxaloacetate ↔ coenzyme A + H+ + (2S,3S)-2-methylcitrate
2 NADPH + 2 H+ + nitrobenzene ↔ 2 NADP+ + H2O + N-phenylhydroxylamine
H2O + benzylbenzoate ↔ benzyl alcohol + H+ + benzoate
dihydromonacolin L acid + H+ ↔ H2O + dihydromonacolin L lactone
2-methylpropanenitrile + NADPH + H+ + oxygen ↔ H2O + NADP+ + 2-hydroxy-2-methylpropanenitrile
L-talarate ↔ H2O + 5-dehydro-4-deoxy-D-glucarate
2 H+ + hydrogen peroxide + Reactive Blue 5 ↔ 2 H2O + oxidized Reactive Blue 5
4-deoxy-β-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + H2O ↔ (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + N-acetyl-β-D-galactosamine
an oxidized electron donor + H2O + N6-dimethylallyladenine ↔ a reduced electron donor + 3-methyl-2-butenal + adenine
3 H2O + an oxidized electron donor + trithionate ↔ 3 sulfite + 4 H+ + a reduced electron donor
3 oxygen + 4 3-hydroxy-4-methylanthranilate ↔ 2 actinocin + 6 H2O
(-)-ent-copalyl diphosphate + H2O ↔ (-)-ent-copalol + diphosphate
H2O + C32-mycoketide-CoA ↔ coenzyme A + C32-mycoketide
2 an oxidized ferredoxin [iron-sulfur] cluster + 2 phosphate + 2 ADP + cyclohex-1,5-diene-1-carbonyl-CoA ↔ 2 H2O + 2 a reduced ferredoxin [iron-sulfur] cluster + 2 ATP + benzoyl-CoA
H2O + N-methylhexanamide ↔ methylamine + hexanoate
hydrogen peroxide + menadiol ↔ 2 H2O + menadione
2 NAD(P)H + 2 H+ + malonyl-CoA + stearoyl-CoA ↔ 2 NAD(P)+ + coenzyme A + H2O + icosanoyl-CoA + CO2
NADPH + 24-hydroxy-β-amyrin + H+ + oxygen ↔ H2O + soyasapogenol B + NADP+
6-hydroxycyclohex-1-ene-1-carbonyl-CoA ↔ H2O + cyclohex-1,5-diene-1-carbonyl-CoA
nocardicin G + oxygen ↔ H2O + H+ + nocardicin E
L-alanin-3-yl L-histidin-5-yl S-oxide ↔ H2O + pyruvate + mercaptohistidine
H2O + 2,5-dioxopiperazine ↔ glycyl-glycine
(2S,3S)-2-methylcitrate ↔ H2O + cis-2-methylaconitate
2-amino-4-oxo-4-α-hydroxy-6-(erythro-1',2',3'-trihydroxypropyl)-5,6, 7,8-tetrahydroxypterin ↔ H2O + 2-amino-4-oxo-6-(1',2',3'-trihydroxypropyl)-diquinoid-7,8-dihydroxypterin
H2O + Nα,Nε-diacetyl-lysyl-D-alanyl-D-alanine ↔ H+ + Nα,Nε-diacetyl-lysyl-D-alanine + D-alanine
L-cysteine + 5-hydroxyindole acetaldehyde ↔ H2O + 5-hydroxyindole thiazolidine carboxylate
2 glutathione + arsenate ↔ H2O + arsenite + glutathione disulfide
H2O + L-gulono-1,4-lactone ↔ L-gulonate + H+
7-deoxyloganate + NADPH + H+ + oxygen ↔ H2O + loganate + NADP+
H2O + malonyl-CoA + ATP + ononin ↔ 2 H+ + coenzyme A + formononetin-7-O-glucoside-6''-malonate + diphosphate + AMP
H2O + dimethylsulfoniopropanoate ↔ 3-hydroxypropanoate + H+ + dimethyl sulfide
2 H+ + 6-deoxocastasterone + oxygen ↔ H2O + 6α-hydroxy-castasterone
H2O + AMP ↔ adenosine + phosphate
H2O + hydrogencarbonate + ATP ↔ phosphate + hydrogencarbonate + ADP
NADPH + tert-amyl alcohol + H+ + oxygen ↔ H2O + 3-methyl-butane-1,3-diol + NADP+
H2O + UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine ↔ UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + L-alanine
a reduced electron donor + CDP ↔ an oxidized electron donor + H2O + dCDP
H2O + P1,P4-bis(5'-adenosyl) tetraphosphate ↔ 2 H+ + AMP + ATP
H2O + N-acetyl-L-ornithine ↔ acetate + L-ornithine
H2O + 4-sulfobenzaldehyde + NAD+ ↔ 2 H+ + 4-sulfobenzoate + NADH
H2O + oxamate ↔ ammonium + oxalate
H2O + 10-formyl-tetrahydrofolate mono-L-glutamate ↔ formate + H+ + 5,6,7,8-tetrahydrofolate
H2O + N-amidino-L-aspartate ↔ L-aspartate + urea
H2O + (2E,5Z)-tetradecenoyl-CoA ↔ (S)-3-hydroxy-(5Z)-tetradecenoyl-CoA
2 H2O + 8-oxo-dGTP ↔ 2 H+ + 2 phosphate + 8-oxo-dGMP
N-cyclohexylformamide ↔ H2O + cyclohexyl-isocyanide
bromochloromethane + H2O ↔ 2 H+ + formaldehyde + chloride + bromide
H2O + γ-glutamyl-ethylamide ↔ ethylamine + L-glutamate
H2O + phenylacetaldehyde + NAD+ ↔ 2 H+ + phenylacetate + NADH
H2O + NAD+ + L-valine ↔ NADH + 3-methyl-2-oxobutanoate + H+ + ammonium
L-fuconate ↔ H2O + 2-dehydro-3-deoxy-L-fuconate
2 H+ + 2 (S)-lactate ↔ 2 H2O + L-lactide
NADPH + H+ + tirandamycin F + oxygen ↔ H2O + NADP+ + tirandamycin E
2 L-ascorbate + oxygen ↔ 2 H2O + 2 L-dehydro-ascorbate
(4-{4-[2-(γ-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + L-glutamate ↔ H2O + 4-[N-γ-L-glutamyl-γ-L-glutamyl-)-p-(β-aminoethyl)phenoxy-methyl]-2-(aminomethyl)furan
H2O + 1-piperideine-2-carboxylate + H+ ↔ 6-amino-2-oxohexanoate
H2O + oleamide ↔ oleate + ammonium
H2O + phosphonate + ATP ↔ phosphate + phosphonate + ADP
hydrogen peroxide + 6-decylubiquinol ↔ 2 H2O + 6-decylubiquinone
L-carnitinyl-CoA ↔ H2O + crotonobetainyl-CoA
2 NADH + 2 H+ + 2 oxygen + (3S,3'S)-astaxanthin ↔ 2 H2O + 2 NAD+ + 2,3,2',3'-tetrahydroxy-β,β-carotene-4,4'-dione
5-S-cysteinyldopa ↔ H2O + 1,4-benzothiazinyl-alanine + H+
H2O + phenyl phosphate + CO2 ↔ H+ + phosphate + 4-hydroxybenzoate
H2O + N-methyl-2-oxoglutaramate ↔ methylamine + 2-oxoglutarate
NAD(P)H + H+ + oxygen + rifampicin ↔ H2O + NAD(P)+ + 2'-N-hydroxyrifampicin
4-methyl-5-nitrocatechol + NADPH + oxygen ↔ H2O + 2-hydroxy-5-methylquinone + NADP+ + H+ + nitrite
H2O + NADP+ + (Z)-2-methylpropanal-oxime ↔ 3 H+ + 2-methylpropanenitrile + NADPH + oxygen
H2O + trimetaphosphate ↔ 2 H+ + triphosphate
H2O + cis-aconitate ↔ D-threo-isocitrate
H2O + sepiapterin + H+ ↔ xanthopterin-B2 + ammonium
2 H+ + oxygen + 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol ↔ H2O + 3-demethylubiquinol-6
3-chloro-D-alanine + H2O ↔ pyruvate + H+ + ammonium + chloride
rhodopin ↔ all-trans-lycopene + H2O
H2O + (S)-2-aminohexano-6-lactam ↔ L-lysine
2-amino-4-carboxypyrimidine + L-alanine ↔ H2O + lathyrine + CO2
H+ + OH- ↔ H2O
phylloquinone + H2O + oxidized dithiothreitol ↔ vitamin K 2,3-epoxide + L-dithiothreitol
H2O + glyoxylate + acetyl-CoA ↔ coenzyme A + (S)-malate + H+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + testosterone + oxygen ↔ 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 1α-hydroxytestosterone
2 an oxidized electron donor + H2O + 4-methylphenol ↔ 2 a reduced electron donor + 4-hydroxybenzaldehyde
2 coenzyme M + methanol ↔ methyl-CoM + H2O
NADPH + H+ + tirandamycin A + oxygen ↔ H2O + NADP+ + tirandamycin B
2 H+ + pentane-1,3,4,5-tetracarboxylate + CO2 ↔ H2O + hexane-6-keto-1,3,4,6-tetracarboxylate
hydroxylamine + ammonium ↔ H2O + H+ + hydrazine
H2O + (S)-piperazine-2-carboxamide ↔ (S)-piperazine-2-carboxylate + ammonium
2 H2O + 2 H+ + methylenediurea ↔ 2 ammonium + N-(hydroxymethyl)urea + CO2
3 NADPH + 4 H+ + oxygen + 3,5,7,9,11,13,15,17,19-nonaoxohenicosanoate ↔ 3 NADP+ + 5 H2O + homo-UWM6 + CO2
H2O + L-arginine ↔ L-ornithine + urea
H2O + (S)-2,3,4,5-tetrahydrodipicolinate + H+ ↔ L-α-amino-ε-keto-pimelate
H2O + creatinine ↔ creatine
bacterioruberin ↔ monoanhydrobacterioruberin + H2O
octanoyl-CoA + H+ + 2-(hydroxylamino)benzoylacetate ↔ coenzyme A + H2O + 2-n-heptyl-4-hydroxyquinoline-N-oxide + CO2
thiamine + H2O + ATP ↔ thiamine + phosphate + ADP
H2O + N-formyl-L-aspartate ↔ formate + L-aspartate
H2O + PAI-1-2 ↔ butanoate + L-homoserine lactone
2 H+ + GDP-4-dehydro-α-D-rhamnose ↔ GDP-4-dehydro-3,6-dideoxy-α-D-mannose + H2O
H2O + acryloyl-CoA ↔ coenzyme A + acrylate + H+
H2O + 1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate ↔ 2 H+ + phosphate + phytate
H2O + fructosevaline-6-phosphate ↔ β-D-glucose 6-phosphate + L-valine
2 H+ + 3-heptaprenyl-4-hydroxybenzoate + oxygen ↔ 3,4-dihydroxy-5-all-trans-heptaprenylbenzoate + H2O
H2O + an oxidized acceptor + indole-3-glycol aldehyde ↔ a reduced electron donor + indole-3-glycolate
H2O + NAD+ + chloroacetaldehyde ↔ 2 H+ + 2-chloroacetate + NADH
2 FMNH2 + 2 oxygen + dibenzothiophene ↔ 2 FMN + 2 H2O + 2 H+ + dibenzothiophene-5,5-dioxide
5,10-methenyl-tetrahydrosarcinapterin + H2O ↔ 5-formyl-tetrahydrosarcinapterin + H+
an oxidized electron donor + H2O + isopentenyl adenosine ↔ trans-zeatin riboside + a reduced electron donor
(+)-copalyl diphosphate + H2O ↔ (+)-copalol + diphosphate
H2O + archaetidylglycerol phosphate ↔ phosphate + unsaturated archaetidylglycerol
H2O + L-cystathionine ↔ L-homoserine + L-cysteine
an oxidized electron donor + H2O + 8-methylquinoline ↔ 8-methylquinolin-2(1H)-one + a reduced electron donor
(24R,25R)-3α,7α,12α,24-tetrahydroxy-5β-cholestanoyl CoA ↔ H2O + (24E)-3α,7α,12α-trihydroxy-5β-cholest-24-enoyl-CoA
(R)-citramalate ↔ H2O + citraconate
2 H+ + H2O + N-carbamoyl-L-aspartate ↔ ammonium + L-aspartate + CO2
NADH + butan-2-one + H+ + oxygen ↔ H2O + 1-hydroxy-2-butanone + NAD+
secologanin + dopamine ↔ H2O + deacetylipecoside
H2O + 2-trans, 4-trans-undecadienoyl-CoA ↔ (3R)-hydroxy, 4-trans-undecenoyl-CoA
2 H2O + butan-2-one + ATP + CO2 ↔ 2 phosphate + 3 H+ + 3-oxopentanoate + AMP
H2O + (2Z,4E)-2-aminomuconate + H+ ↔ (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + ammonium
panose + H2O ↔ isomaltose + D-glucopyranose
L-homocysteine thiolactone + H2O ↔ L-homocysteine + H+
ginsenoside Rh1 + H2O ↔ protopanaxatriol + D-glucopyranose
gentiobiose + H2O ↔ 2 D-glucopyranose
ginsenoside Re + H2O ↔ ginsenoside Rg1 + L-rhamnopyranose
ammonium + hydrogencarbonate + ATP ↔ H2O + carbamoyl phosphate + H+ + ADP
ginsenoside Rf + H2O ↔ ginsenoside Rh1 + D-glucopyranose
GDP-4-dehydro-α-D-rhamnose + H2O + L-glutamate ↔ 2 H+ + 2-oxoglutarate + GDP-α-D-perosamine
H2O + juvenile hormone II ↔ juvenile hormone II acid + methanol + H+
H2O + 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA ↔ 3-hydroxypimeloyl-CoA + H+
4-diphospho-1D-myo-inositol pentakisphosphate + H2O ↔ 2 H+ + phytate + phosphate
1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + 2 H+ + phosphate ↔ 4,5-bis(diphospho)-1D-myo-inositol tetrakisphosphate + H2O
1D-myoinositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + 2 H+ + phosphate ↔ 5,6-bis(diphospho)-1D-myo-inositol tetrakisphosphate + H2O
6-diphospho-1D-myo-inositol pentakisphosphate + H2O ↔ 2 H+ + phytate + phosphate
H2O + leukotriene A4 ↔ (5S,6S)-di-HETE
allantoin + H2O ↔ allantoate + H+
H2O + 2 NAD+ + decan-1-ol ↔ 2 H+ + 2 NADH + decanal
H2O + 2 NAD+ + 1-dodecanol ↔ 2 H+ + 2 NADH + dodecanal
6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O ↔ 6-(alpha-D-Glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate + H+
H2O + leukotriene A4 ↔ (5S,6S)-di-HETE
H2O + leukotriene A4 ↔ Δ6-trans,Δ8-cis-leukotriene B4
3-hydroxyicosanoyl-CoA ↔ H2O + trans-2-icosenoyl-CoA
3-hydroxydocosanoyl-CoA ↔ H2O + trans-docos-2-enoyl-CoA
3-hydroxybutanoyl-ACP ↔ H2O + trans-but-2-enoyl-ACP
3-hydroxyhexanoyl-ACP ↔ H2O + trans-Hex-2-enoyl-ACP
(3R)-3-hydroxyoctanoyl-ACP ↔ H2O + trans-oct-2-enoyl-ACP
H2O + 2 NAD+ + 1-hexadecanol ↔ 2 H+ + 2 NADH + palmitaldehyde
(S)-3-hydroxyhexacosanoyl-CoA ↔ H2O + (2E)-hexadecenoyl-CoA
H2O + 2 NAD+ + C00289 ↔ 3 H+ + 2 NADH + UDP-α-D-glucuronate
D-ribose 5-phosphate + uracil ↔ H2O + pseudouridine 5'-phosphate
aldehydo-D-ribose 5-phosphate + uracil ↔ H2O + pseudouridine 5'-phosphate