Compound as reactive (5)
H
2
O +
thiamine diphosphate
+ ATP →
thiamine diphosphate
+ phosphate + ADP
thiamine diphosphate
+ ATP → thiamine triphosphate + ADP
thiamine diphosphate
+ pyruvate + H
+
→ 2-(α-hydroxyethyl)thiamine diphosphate + CO
2
2 H2O +
thiamine diphosphate
→ H+ + 2 phosphate + thiamine
ATP +
thiamine diphosphate
→ ADP + dTTP
Compound as product (4)
H
2
O +
thiamine diphosphate
+ ATP →
thiamine diphosphate
+ phosphate + ADP
thiamine + ATP →
thiamine diphosphate
+ H
+
+ AMP
thiamine phosphate + ATP →
thiamine diphosphate
+ ADP
H
2
O + thiamine triphosphate →
thiamine diphosphate
+ H
+
+ phosphate
Reversible reaction (5)
thiamine diphosphate
+ (
S
)-2-acetolactate ↔ 2-(α-hydroxyethyl)thiamine diphosphate + pyruvate
H
2
O +
thiamine diphosphate
↔ thiamine phosphate + H
+
+ phosphate
isochorismate + succinate-semialdehyde-thiamine PPi ↔
thiamine diphosphate
+ (1
S
,6
R
)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate + pyruvate
thiamine diphosphate
+ H
+
+ ADP ↔ adenosine thiamine triphosphate + phosphate
thiamine diphosphate
+ 2-oxoglutarate ↔ succinate-semialdehyde-thiamine PPi + CO
2