NAD(P)H + H+ + oxygen + (4'R)-11'-hydroxy-10'-methoxy-5'-azaspiro[cyclohexane-1,2'-tricyclo[6.3.1.04,��]dodecane]-'(12'),2,5,8',10'-pentaen-4-one → H2O + NAD(P)+ + formaldehyde + (4'R)-10',11'-dihydroxy-5'-azaspiro[cyclohexane-1,2'-tricyclo[6.3.1.04,��]dodecane]-'(12'),2,5,8',10'-pentaen-4-one