Compound as reactive (3)
H
+
+
aldehydo
-D-ribose 5-phosphate + ATP ←
diphosphate
+ ADP-D-ribose
L-serine +
diphosphate
→ 3-phospho-L-serine + H
+
+ phosphate
H
2
O +
diphosphate
→ 2 phosphate + H
+
Compound as product (851)
L-leucine + (-)-jasmonate + ATP → H
+
+
diphosphate
+ (-)-jasmonoyl-L-leucine + AMP
diphosphate
+ IMP ← 5-phospho-α-D-ribose 1-diphosphate + hypoxanthine
N
3
-oct-2-enoyl-
N
3
-hydroxy-1,3-diaminopropane + ATP + citrate →
N
1
-citryl-
N
3
-oct-2-enoyl-
N
3
-hydroxy-1,3-diaminopropane + H
+
+
diphosphate
+ AMP
all-
trans
-heptaprenyl diphosphate → β-heptaprene +
diphosphate
coenzyme A + cholate + ATP → choloyl-CoA +
diphosphate
+ AMP
2 ATP + 2 (indol-3-yl)pyruvate → 2
diphosphate
+ 2 AMP + didemethylasterriquinone D
isopentenyldehydrorhodopin + H
2
O + prenyl diphosphate → dihydrobisanhydrobacterioruberin +
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate → (3
R
,6
E
)-nerolidol +
diphosphate
(2
S
)-naringenin + prenyl diphosphate → sophoraflavanone B +
diphosphate
a tRNAtyr + H
+
+ L-tyrosine + ATP → an L-tyrosyl-[tRNAtyr] +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-β-amorphene
(+)-copalyl diphosphate → (+)-isopimara-7,15-diene +
diphosphate
3-deoxy-α-D-
manno
-2-octulosonate + CTP →
diphosphate
+ CMP-3-deoxy-β-D-
manno
-octulosonate
(2R,3S)-2-octyl-3-hydroxydodecanoate + ATP → 4-nonyl-3-octyl-oxetan-2-one +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-cyperene
N
5
-2,4-diaminobutanoate-
N
1
-citryl-
N
3
-decanoyl-
N
3
-hydroxy-1,3-diaminopropane + 2-oxoglutarate + ATP → baumannoferrin B + H
+
+
diphosphate
+ AMP
coenzyme A + 4-hydroxybenzoate + ATP → 4-hydroxybenzoyl-CoA +
diphosphate
+ AMP
2 NADPH + 2
S
-adenosyl-L-methionine + 2 oxygen + 4-methylsalicylate + H
+
+ all-
trans
-hexaprenyl diphosphate → 2 H
2
O + 2
S
-adenosyl-L-homocysteine + 2 NADP
+
+ 3-demethylubiquinol-6 +
diphosphate
+ CO
2
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ δ-guaiene
neryl diphosphate → (+)-2-carene +
diphosphate
H
+
+ geranylgeranyl diphosphate + bacteriochlorophyllide
b
→
diphosphate
+ geranylgeranyl bacteriochlorophyllide
b
H
2
O + geranylgeranyl diphosphate → α-cembratriene-ol +
diphosphate
geranyl diphosphate → (+)-2-carene +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-β-curcumene
prenyl diphosphate + H
+
+ ATP →
N
6
-(Δ
2
-isopentenyl)-adenosine 5'-triphosphate +
diphosphate
3 ATP + anthranilate + L-tryptophan + L-alanine → 2 H
+
+ 3
diphosphate
+ 3 AMP + H
2
O + ardeemin FQ
D-
glycero
-β-D-
manno
-heptose 1-phosphate + H
+
+ ATP → ADP-D-glycero-β-D-
manno
-heptose +
diphosphate
(-)-
ent
-copalyl diphosphate → (
Z
)-biformene +
diphosphate
an oxidized electron donor +
all-trans
-lycopene + H
2
O + prenyl diphosphate → nonaflavuxanthin + a reduced electron donor +
diphosphate
H
2
O + prenyl diphosphate →
diphosphate
+ isoprenyl alcohol
9α-copalyl diphosphate + H
2
O →
syn
-copalol +
diphosphate
fusicoccin P + prenyl diphosphate → fusicoccin J +
diphosphate
8 isopentenyl diphosphate + (2
E
,6
E
)-farnesyl diphosphate → 8
diphosphate
+ all-
trans
-undecaprenyl diphosphate
spermidine + ATP + citrate →
N
-citryl-spermidine + H
+
+
diphosphate
+ AMP
prenyl diphosphate + genistein → wighteone +
diphosphate
prenyl diphosphate + (R)-benzodiazepinedione →
diphosphate
+ aszonalenin
tabtoxinine-β-lactam + L-threonine + ATP → β-tabtoxin + H
+
+
diphosphate
+ AMP
geranylgeranyl diphosphate → hydropyrene +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-δ-cadinene
prenyl diphosphate + lolitriol → lolitrem E +
diphosphate
α-linolenate + coenzyme A + ATP → α-linolenoyl-CoA +
diphosphate
+ AMP
5,7-diacetamido-3,5,7,9-tetradeoxy-D-
glycero
-D-
galacto
-nonulopyranosonate + CTP →
diphosphate
+ CMP-
N
,
N
'-diacetyllegionaminate
(-)-glycinol + prenyl diphosphate → (6α
S
,11α
S
)-2-dimethylallyl-3,6α,9-trihydroxypterocarpan +
diphosphate
(
S
)-2-amino-6-oxohexanoate + NADP
+
+
diphosphate
+ AMP ← NADPH + L-2-aminoadipate + H
+
+ ATP
H
+
+
sn
-glycerol 3-phosphate + CTP → CDP-glycerol +
diphosphate
coenzyme A + salicylate + ATP → salicyl-CoA +
diphosphate
+ AMP
coenzyme A + propanoate + ATP → propanoyl-CoA +
diphosphate
+ AMP
2 prenyl diphosphate + terpendole I → 2
diphosphate
+ 20,21-diprenylterpendole I
H
2
O + dUTP → H
+
+
diphosphate
+ dUMP
1-(2-amino-2-deoxy-α-D-glucopyranosyl)-1D-myo-inositol + L-cysteine + ATP → deacetylmycothiol + H
+
+
diphosphate
+ AMP
2 3-(4-hydroxyphenyl)pyruvate + 2 ATP → 2
diphosphate
+ 2 AMP + atromentin
H
2
O + geranylgeranyl diphosphate → β-cembratriene-ol +
diphosphate
N-dimethylethanolamine phosphate + H
+
+ CTP → CDP-
N
-dimethylethanolamine +
diphosphate
α-D-glucosamine 1-phosphate + H
+
+ GTP →
diphosphate
+ GDP-D-glucosamine
coenzyme A + (25
R
)-3α,7α-dihydroxy-5-β-cholestanate + ATP → H
+
+ (25
R
)-3α,7α-dihydroxy-5β-cholestanoyl-CoA +
diphosphate
+ AMP
N
5
-phospho-L-glutamine + H
+
+ CTP →
N
5
-(cytidine 5'-diphosphoramidyl)-L-glutamine +
diphosphate
L-glutamate + ATP + 4-aminobenzoate →
N
-(4-aminobenzoyl)-L-glutamate + H
+
+
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-β-barbatene
prenyl diphosphate + terpendole I → terpendole J +
diphosphate
coenzyme A + L-firefly luciferin + ATP → L-firefly luciferyl-CoA +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-γ-muurolene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ β-himachalene
2 H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ 7-
epi
-
ent
-eudesmane-5,11-diol
H
+
+ linoleate + ATP → linoleyl-AMP +
diphosphate
coenzyme A + ferulate + ATP →
trans
-feruloyl-CoA +
diphosphate
+ AMP
prephytoene diphosphate → 15-
cis
-phytoene +
diphosphate
biotin + H
+
+ ATP →
diphosphate
+ biotinyl-5'-adenylate
(7,8-dihydropterin-6-yl)methyl diphosphate + 4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate → 2 H
+
+ 7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate +
diphosphate
prenyl diphosphate + naringenin chalcone → desmethylxanthohumol + H
+
+
diphosphate
(-)-
ent
-copalyl diphosphate →
ent
-isokaurene +
diphosphate
L-proline + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-proline + H
+
+
diphosphate
+ AMP
H
2
O + geranylgeranyl diphosphate → ent-16-a-hydroxy-kaurene +
diphosphate
β-nicotinamide D-ribonucleotide +
diphosphate
← 5-phospho-α-D-ribose 1-diphosphate + nicotinamide + H
+
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-β-santalene
(+)-copalyl diphosphate + H
2
O → manool +
diphosphate
L-5-hydroxy-5-formylornithine + ATP → L-hfOrn-AMP +
diphosphate
H
2
O + presqualene diphosphate → hydroxysqualene +
diphosphate
coenzyme A + (2
E
)-hexadecenoate + ATP →
diphosphate
+ (2E)-hexadecenoyl-CoA + AMP
H
+
+ ATP + D-alanine → (D-alanyl)adenylate +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-cubenene
coenzyme A + 3-[(3a
S
,4
S
,7a
S
)-7a-methyl-1,5-dioxo-octahydro-1
H
-inden-4-yl]propanoate + ATP → 3-[(3a
S
,4
S
,7a
S
)-7a-methyl-1,5-dioxo-octahydro-1
H
-inden-4-yl]propanoyl-CoA +
diphosphate
+ AMP
β-D-fructofuranose 6-phosphate + H
+
+ CTP →
diphosphate
+ CDP-D-fructose
(2
E
,6
E
)-farnesyl diphosphate → longifolene +
diphosphate
ATP →
diphosphate
+ cyclic-AMP
1,4-dihydroxy-2-naphthoate + H
+
+ all-
trans
-undecaprenyl diphosphate → demethylmenaquinol-11 +
diphosphate
+ CO
2
valienol 1-phosphate + H
+
+ GTP → GDP-valienol +
diphosphate
prenyl diphosphate + 3-(4-hydroxyphenyl)pyruvate →
diphosphate
+ 3-dimethylallyl-4-hydroxyphenylpyruvate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-thujopsene
coenzyme A + linoleate + ATP → linoleoyl-CoA +
diphosphate
+ AMP
H
+
+ 2,3-bis-
O
-phytanyl-
sn
-glycerol 1-phosphate + CTP → saturated CDP-archaeol +
diphosphate
(+)-copalyl diphosphate → abieta-7,13-diene +
diphosphate
(-)-glycinol + prenyl diphosphate → (6α
S
,11α
S
)-4-dimethylallyl-3,6α,9-trihydroxypterocarpan +
diphosphate
isopentenyl diphosphate + geranylgeranyl diphosphate → geranylfarnesyl diphosphate +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (Z,E)-α-farnesene
behenate + H
+
+ ATP → (behenoyl)adenylate +
diphosphate
(2Z,6Z)-farnesyl diphosphate →
diphosphate
+ (+)-
endo
-β-bergamotene
2
N
-hydroxy-
N
-succinyl-putrescine + ATP → pre-putrebactin + H
+
+
diphosphate
+ AMP
H
+
+ L-leucine + LEU-tRNAs + ATP → Charged-LEU-tRNAs +
diphosphate
+ AMP
13 isopentenyl diphosphate + (2
E
,6
E
)-farnesyl diphosphate → 13
diphosphate
+
di-trans, poly-cis
-polyprenyl diphosphate (C
80
)
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-β-chamigrene
3 isopentenyl diphosphate + (2
E
,6
E
)-farnesyl diphosphate → 3
diphosphate
+ all-
trans
-hexaprenyl diphosphate
2-methyl-4-hydroxyquinoline + (2
E
,6
E
)-farnesyl diphosphate → aurachin D +
diphosphate
12-ethyl-8-propylbacteriochlorophyllide
c
+ H
+
+ (2
E
,6
E
)-farnesyl diphosphate → 12-ethyl-8-propylbacteriochlorophyll
c
+
diphosphate
(2
Z
,6
E
)-farnesyl diphosphate → (+)-2-
epi
-prezizaene +
diphosphate
H
2
O + GTP → H
+
+
diphosphate
+ GMP
H
2
O + L-glutamine + ATP + nicotinate adenine dinucleotide → NAD
+
+ H
+
+ L-glutamate +
diphosphate
+ AMP
coenzyme A + H
2
O + chrysanthemyl diphosphate → (1R,3R)-chrysanthemoyl CoA +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ 7-
epi
-sesquithujene
(-)-
ent
-copalyl diphosphate →
ent
-pimara-8(14),15-diene +
diphosphate
1D-
myo
-inositol 3-monophosphate + H
+
+ CTP →
diphosphate
+ CDP-1L-
myo
-inositol
coenzyme A + 2-succinylbenzoate + ATP → 4-(2'-carboxyphenyl)-4-oxobutyryl-CoA +
diphosphate
+ AMP
geranyl diphosphate →
diphosphate
+ (+)-β-pinene
H
+
+ GTP + adenosyl-cobinamide phosphate →
diphosphate
+ adenosylcobinamide-GDP
dalbergioidin + prenyl diphosphate → kievitone +
diphosphate
2 H
+
+ an oxidized electron donor + hydrodidemethylasterriquinone D + prenyl diphosphate → ochrindole D + H
2
O + a reduced electron donor +
diphosphate
19-(4-hydroxyphenyl)nonadecanoate + H
+
+ ATP → 19-(4-hydroxyphenyl)nonadecanoyl adenylate +
diphosphate
coenzyme A + 3-phenylpropanoate + ATP → 3-phenylpropanoyl-CoA +
diphosphate
+ AMP
(2
S
)-2-phospholactate + H
+
+ GTP → (2
S
)-lactyl-2-diphospho-5'-guanosine +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ longicyclene
D-ribitol 5-phosphate + H
+
+ CTP → CDP-ribitol +
diphosphate
1,4-dihydroxy-2-naphthoate + H
+
+
all-trans
-nonaprenyl diphosphate → demethylmenaquinol-9 +
diphosphate
+ CO
2
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-sativene
presqualene diphosphate → 15-
cis
-4,4'-diapophytoene +
diphosphate
L-N
2
-(2-carboxyethyl)arginine + ATP → deoxyamidinoproclavaminate + H
+
+
diphosphate
+ AMP
3 L-(4-hydroxyphenyl)glycine + 5 ATP + H
2
O + L-serine + L-arginine → 5 H
+
+ 5
diphosphate
+ 5 AMP + L-4-hydroxyphenylglycine-L-arginyl-D-4-hydroxyphenylglycine-L-seryl-L 4-hydroxyphenylglycine
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ β-gurjunene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ γ-humulene
coenzyme A + pseudomonate C + ATP → pseudomonoyl-CoA C +
diphosphate
+ AMP
5 isopentenyl diphosphate + geranylgeranyl diphosphate → 5
diphosphate
+
all-trans
-nonaprenyl diphosphate
H
2
O + geranyl diphosphate →
diphosphate
+ (-)-(4
S
)-α-terpineol
H
2
O + geranyl diphosphate →
diphosphate
+ (+)-α-terpineol
prephytoene diphosphate + NADPH + H
+
→ lycopaoctaene + NADP
+
+
diphosphate
(
R
)-4'-phosphopantothenate + L-cysteine + CTP → (R)-4'-phosphopantothenoyl-L-cysteine + CMP + H
+
+
diphosphate
H
+
+ L-threonine + ATP → (L-threonyl)adenylate +
diphosphate
3 2,3-dihydroxybenzoate + 3 glycine + 3 L-threonine + 6 ATP → 3 H
2
O + 3 H
+
+ 6
diphosphate
+ 6 AMP + bacillibactin
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-α-amorphene
geranyl diphosphate →
diphosphate
+ (-)-3-carene
2 geranylgeranyl diphosphate → prephytoene diphosphate +
diphosphate
(2Z,6Z)-farnesyl diphosphate →
diphosphate
+ 7-epizingiberene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (Z) γ-bisabolene
GTP → cyclic pyranopterin phosphate +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (E) γ-bisabolene
4'-phosphopantetheine + H
+
+ ATP → 3'-dephospho-CoA +
diphosphate
2 H
+
+ 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate → thiamine phosphate +
diphosphate
+ CO
2
prenyl diphosphate + deoxycohumulone →
diphosphate
+ colupulone
pppGp(2'-5')A → cyclic Gp(2'-5')Ap(3'-5') +
diphosphate
[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl triphosphate]-D-ribitol + (
S
)-2-hydroxyglutarate → demethylated 7,8-dihydromethanopterin +
diphosphate
H
+
+ L-alanine + ATP → (L-alanyl)adenylate +
diphosphate
glycine + ATP → (glycyl)adenylate +
diphosphate
prenyl diphosphate + deoxycohumulone + geranyl diphosphate → 2
diphosphate
+ hyperforin
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (3S)-(+)-asterisca-2(9),6-diene
H
+
+ GTP + α-D-glucopyranose 1-phosphate → GDP-α-D-glucose +
diphosphate
H
2
O + protoheme + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ ferroheme
o
isopentenyl diphosphate + prenyl diphosphate →
diphosphate
+ neryl diphosphate
9α-copalyl diphosphate → (-)-9β-pimara-7,15-diene +
diphosphate
coenzyme A + 3-oxo-3-phenylpropanoate + ATP → 3-oxo-3-phenylpropanoyl-CoA +
diphosphate
+ AMP
geranylgeranyl diphosphate → (-)-spiroviolene +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-
epi
-isozizaene
all-
trans
-heptaprenyl diphosphate →
diphosphate
+ tetraprenyl-β-curcumene
coenzyme A + 4-coumarate + ATP → (
E
)-4-coumaroyl-CoA +
diphosphate
+ AMP
NAD(P)H + 3-amino-4-hydroxybenzoate + H
+
+ ATP → 3-amino-4-hydroxybenzaldehyde + NAD(P)+ +
diphosphate
+ AMP
coenzyme A + phytenate + ATP → phytenoyl-CoA +
diphosphate
+ AMP
isopentenyl diphosphate + di-
trans
,poly-
cis
-decaprenyl diphosphate → 5 H
+
+
di-trans,octa-cis
-undecaprenyl diphosphate +
diphosphate
L-2,3-diaminopropanoate + fumarate + ATP →
N
-3-fumaroyl-L-2,3-diaminopropanoate + H
+
+
diphosphate
+ AMP
H
2
O + L-glutamine + XMP + ATP → 2 H
+
+ L-glutamate +
diphosphate
+ AMP + GMP
10 ATP + 3 L-threonine + 6 L-2,4-diaminobutanoate + L-leucine + 6-methyloctanoyl-CoA → 10
diphosphate
+ 10 AMP + 11 H
+
+ coenzyme A + polymyxin A
3-(
O
-geranylgeranyl)-
sn
-glycerol 1-phosphate + geranylgeranyl diphosphate →
diphosphate
+ 2,3-bis-
O
-(geranylgeranyl)-
sn
-glycerol 1-phosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ 5-
epi
-α-selinene
3 ATP + H
2
O + L-2-aminoadipate + L-valine + L-cysteine → 3 H
+
+ 3
diphosphate
+ 3 AMP +
N
-[(5
S
)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine
H
2
O + triphosphate →
diphosphate
+ phosphate
ditrans,octacis
-undecaprenyldiphospho-
N
-acetyl-(
N
-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanyl-D-alanine + ammonium + ATP →
ditrans,octacis
-undecaprenyldiphospho-
N
-acetyl-(
N
-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine + H
+
+
diphosphate
+ AMP
coenzyme A + octanoate + ATP → octanoyl-CoA +
diphosphate
+ AMP
ammonium + L-aspartate + ATP → H
+
+ L-asparagine +
diphosphate
+ AMP
prenyl diphosphate + ardeemin FQ →
diphosphate
+ ardeemin
H
2
O + geranyl diphosphate →
diphosphate
+ (3S)-linalool
H
2
O + geranyl diphosphate →
diphosphate
+ (3R)-linalool
geranyl diphosphate → (+)-sabinene +
diphosphate
(+)-copalyl diphosphate + H
2
O → 13-
epi
-manool +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-δ-amorphene
(-)-indolactam V + geranyl diphosphate → lyngbyatoxin A +
diphosphate
(+)-copalyl diphosphate → miltiradiene +
diphosphate
3
N
-hydroxy-
N
-succinylcadaverine + ATP → H
2
O + desferrioxamine G
1
+ H
+
+
diphosphate
+ AMP
5 H
+
+ MoO
2
-molybdopterin cofactor + GTP → 2 H
2
O + guanylyl molybdenum cofactor +
diphosphate
prenyl diphosphate + brevianamide F → tryprostatin B +
diphosphate
phytyl diphosphate + H
+
+ chlorophyllide
b
→
diphosphate
+ chlorophyll
b
geranylgeranyl diphosphate → β-pinacene +
diphosphate
H
2
O + dATP → H
+
+
diphosphate
+ dAMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ valerena-4,7(11)-diene
prenyl diphosphate + umbelliferone → demethylsuberosin +
diphosphate
prenyl diphosphate + paspalinine → aflatrem +
diphosphate
vanillate + L-glutamate + ATP → H
+
+
diphosphate
+ AMP +
N
-vanillate-L-glutamate
(2Z,6Z)-farnesyl diphosphate →
diphosphate
+ (+)-α-santalene
ammonium + XMP + ATP → 2 H
+
+
diphosphate
+ AMP + GMP
prenyl diphosphate + histidyltryptophyldiketopiperazine →
diphosphate
+ roquefortine D
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-α-cedrene
coenzyme A + 2-hydroxy-2-methylpropanoate + ATP → 2-hydroxy-2-methylpropanoyl-CoA +
diphosphate
+ AMP
prenyl diphosphate + phlorisobutanophenone → 4-prenylphlorisobutyrophenone +
diphosphate
neryl diphosphate →
diphosphate
+ (-)-α-pinene
geranyl diphosphate →
diphosphate
+ (-)-α-pinene
prenyl diphosphate + 4-prenylphlormethylbutanophenone → deoxyadlupulone +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-α-cadinene
L-firefly luciferin + H
+
+ ATP → (L-firefly luciferyl)adenylate +
diphosphate
H
2
O + (+)-bornyl-diphosphate →
diphosphate
+ (+)-borneol
coenzyme A + [(1R)-4,5,5-trimethyl-2-oxocyclopent-3-enyl]acetate + ATP → [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + H
+
+
diphosphate
+ AMP
coenzyme A + 4-hydroxybenzoyl-acetate + ATP →
diphosphate
+ 3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + AMP
H
2
O + α-D-ribose 1-(acetamidomethylphosphonate) 5-triphosphate → α-D-ribose-1-(2-
N
-acetamidomethylphosphonate) 5-phosphate + H
+
+
diphosphate
4-hydroxybenzoate + geranyl diphosphate → 3-geranyl-4-hydroxybenzoate +
diphosphate
8-amino-3,8-dideoxy-α-D-
manno
-octulosonate + CTP →
diphosphate
+ CMP-8-amino-3,8-dideoxy-α-D-
manno
-octulosonate
coenzyme A + ATP + oxalate → oxalyl-CoA +
diphosphate
+ AMP
diaminobutyryl-citryl-ethanolamine + 2-oxoglutarate + ATP → α-ketoglutaryl-diaminobutyryl-citryl-ethanolamine + H
+
+
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate → (+)-δ-selinene +
diphosphate
leachianone G + prenyl diphosphate + H
+
→ sophoraflavanone G +
diphosphate
2'-hydroxygenistein + prenyl diphosphate → luteone +
diphosphate
(3
1
R)-8-ethyl-12-methylbacteriochlorophyllide
d
+ H
+
+ (2
E
,6
E
)-farnesyl diphosphate → (3
1
R)-8-ethyl-12-methylbacteriochlorophyll
d
+
diphosphate
3-[(2-aminopentan-5-oylcarbamoyl)methyl]-3-hydroxybutanoate + ATP + citrate → H
+
+ staphyloferrin A +
diphosphate
+ AMP
2'-hydroxygenistein + prenyl diphosphate → 2,3-dehydrokievitone +
diphosphate
all-
trans
-decaprenyl diphosphate + 4-hydroxybenzoate → 3-decaprenyl-4-hydroxybenzoate +
diphosphate
coenzyme A + ATP + 3-hydroxybenzoate → 3-hydroxybenzoyl-CoA +
diphosphate
+ AMP
anthranilate + coenzyme A + ATP → anthraniloyl-CoA +
diphosphate
+ AMP
all-
trans
-hexaprenyl diphosphate + 4-aminobenzoate →
diphosphate
+ 3-hexaprenyl-4-aminobenzoate
geranylfarnesyl diphosphate + 2-hydroxyphenazine → 2-(geranylfernesyl)phenazine +
diphosphate
geranyl diphosphate →
diphosphate
+ (-)-β-pinene
(13E)-labda-7,13-dien-15-yl diphosphate + H
2
O → (13
E
)-labda-7,13-dien-15-ol +
diphosphate
5-phospho-α-D-ribose-1-preQ
0
+
diphosphate
← 5-phospho-α-D-ribose 1-diphosphate + preQ
0
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-α-bulgarene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ γ-curcumene
H
+
+ UTP + α-D-glucopyranose 1-phosphate →
diphosphate
+ UDP-α-D-glucose
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ γ-himachalene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ isobazzanene
didemethylasterriquinone D + prenyl diphosphate → asterriquinone C1 +
diphosphate
coenzyme A + 4-hydroxypentanoate + ATP → 4-hydroxypentanoyl-CoA +
diphosphate
+ AMP
pre-alcaligin + ATP → alcaligin + H
+
+
diphosphate
+ AMP
H
+
+ MoO
2
-molybdopterin cofactor + ATP → adenylyl molybdenum cofactor +
diphosphate
neryl diphosphate → α-terpinene +
diphosphate
geranyl diphosphate → α-terpinene +
diphosphate
H
+
+ ADP + ATP → P
1
,P
3
-
bis
(5'-adenosyl) triphosphate +
diphosphate
H
2
O + geranyl diphosphate →
diphosphate
+ (-)-
endo
-fenchol
H
2
O + geranyl diphosphate →
diphosphate
+ geraniol
H
+
+
N
-acetyldemethyl-L-phosphinothricin + ATP →
N
-acetyldemethylphosphinothricin adenylate +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ α-humulene
isopentenyl diphosphate + geranylfarnesyl diphosphate → all-
trans
-hexaprenyl diphosphate +
diphosphate
N
1
-citryl-
N
3
-decanoyl-
N
3
-hydroxy-1,3-diaminopropane + L-2,4-diaminobutanoate + ATP →
N
5
-2,4-diaminobutanoate-
N
1
-citryl-
N
3
-decanoyl-
N
3
-hydroxy-1,3-diaminopropane + H
+
+
diphosphate
+ AMP
β-L-fucose 1-phosphate + H
+
+ GTP →
diphosphate
+ GDP-β-L-fucose
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ germacrene C
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (
E
)-β-farnesene
H
2
O + geranylgeranyl diphosphate → (13
E
)-labda-7,13-dien-15-ol +
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate → 10-
epi
-cubebol +
diphosphate
geranylgeranyl diphosphate → cembrene C +
diphosphate
esculetin + geranyl diphosphate → 8-geranylesculetin +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-isoitalicene
3 2,3-dihydroxybenzoate + 3 L-serine + 6 ATP → 3 H
+
+ 6
diphosphate
+ 6 AMP + enterobactin
prenyl diphosphate → isoprene +
diphosphate
H
2
O + α-D-ribose-1-[
N
-(phosphonomethyl)glycine] 5-triphosphate → α-D-ribose-1-[
N
-(phosphonomethyl)glycine] 5-phosphate + H
+
+
diphosphate
coenzyme A + 3-hydroxypropanoate + NADPH + H
+
+ ATP → H
2
O + propanoyl-CoA + NADP
+
+
diphosphate
+ AMP
(13
E
)-8α-hydroxylabd-13-en-15-yl diphosphate → 13-epi manoyl oxide +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-α-santalene
H
2
O + (2
E
,6
E
)-farnesyl diphosphate → (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ eudesma-4,11-diene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ β-longipinene
H
2
O + geranylfarnesyl diphosphate → ophiobolin F +
diphosphate
2 (2
E
,6
E
)-farnesyl diphosphate → presqualene diphosphate +
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate → drimenol +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (1R,4R,5S)-(-)-guaia-6,10(14)-diene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ β-selinene
5-phospho-α-D-ribose 1-diphosphate + neamine →
diphosphate
+ 5''-phosphoribostamycin
(2Z,6Z)-farnesyl diphosphate →
diphosphate
+ (-)-
endo
-α-bergamotene
geranyl diphosphate → (-)-2-carene +
diphosphate
H
+
+ 1,4-dihydroxy-6-naphthoate + all-
trans
-hexaprenyl diphosphate → demethylmenaquinol-6 +
diphosphate
+ CO
2
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ α-ylangene
2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate + ATP → H
+
+ staphyloferrin B +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ guaia-6,9-diene
(2
E
,6
E
)-farnesyl diphosphate → (+)-germacrene A +
diphosphate
coenzyme A + 3-hydroxypropanoate + ATP → 3-hydroxypropanoyl-CoA +
diphosphate
+ AMP
2 3-[4-amino-3-hydroxybutyl]-hydroxy-carbamoyl-propanoate + ATP → pre-alcaligin + H
+
+
diphosphate
+ AMP
(+)-copalyl diphosphate → palustradiene +
diphosphate
UMP +
diphosphate
← 5-phospho-α-D-ribose 1-diphosphate + uracil
all-
trans
-hexaprenyl diphosphate + 4-amino-3-methoxybenzoate → 3-hexaprenyl-4-amino-5-methoxybenzoate +
diphosphate
phosphocholine + H
+
+ CTP → CDP-choline +
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ avermitilol
1,4-dihydroxy-2-naphthoate + H
+
+ all-
trans
-hexaprenyl diphosphate → demethylmenaquinol-6 +
diphosphate
+ CO
2
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-corvol ether A
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ sibirene
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ 8-epi-cedrol
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ β-eudesmol
L-methionine + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-methionine + H
+
+
diphosphate
+ AMP
coenzyme A + sulfoacetate + ATP → sulfoacetyl-CoA +
diphosphate
+ AMP
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-isoafricanol
L-cysteine + ATP → (L-cysteinyl)adenylate +
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ intermedeol
oxidized coenzyme F
420
-2 + H
+
+ ATP →
diphosphate
+ coenzyme F
390
-A
5-phospho-α-D-ribose 1-diphosphate + H
+
+ 4-hydroxybenzoate → 4-(β-D-ribofuranosyl)hydroxybenzene 5'-phosphate +
diphosphate
+ CO
2
H
2
O + GTP → 7,8-dihydroneopterin 2',3'-cyclic phosphate + formate + H
+
+
diphosphate
geranylgeranyl diphosphate → pseudolaratriene +
diphosphate
H
2
O + UDP-
N
-acetyl-α-D-muramoyl-L-alanyl-L-glutamate + ATP → H
+
+
diphosphate
+ UDP-
N
-acetyl-α-D-muramoyl-L-alanyl-D-glutamate + AMP
prenyl diphosphate + hapalindole U →
diphosphate
+ ambiguine H
H
2
O + geranylgeranyl diphosphate → geranylgeraniol +
diphosphate
5-phospho-α-D-ribose 1-diphosphate + paromamine →
diphosphate
+ 5''-phosphoribosylparomamine
1,4-dihydroxy-2-naphthoate + H
+
+ all-
trans
-dodecaprenyl diphosphate → demethylmenaquinol-12 +
diphosphate
+ CO
2
oxidized coenzyme F
420
-2 + H
+
+ GTP → coenzyme F
390
-G +
diphosphate
prenyl diphosphate + umbelliferone → osthenol +
diphosphate
17-(4-hydroxyphenyl)heptadecanoate + H
+
+ ATP → 17-(4-hydroxyphenyl)heptadecanoyl adenylate +
diphosphate
H
2
O + dCTP → H
+
+
diphosphate
+ dCMP
pyridin-1-ium-3,5-dicarboxylate mononucleotide + H
+
+ ATP → 5-carboxy-1-(5-O-phospho-β-D-ribofuranosyl)pyridin-1-ium-3-carbonyl adenylate +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+
cis
-muurola-3,5-diene
terpentedienyl diphosphate → terpentetriene +
diphosphate
pseudaminate + CTP →
diphosphate
+ CMP-pseudaminate
geranyl diphosphate → (+)-camphene +
diphosphate
coenzyme A + phytanate + ATP → phytanoyl-CoA +
diphosphate
+ AMP
H
2
O + UTP → UMP + H
+
+
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ β-copaene
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ 10-
epi
-γ-eudesmol
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-(1(10)E,4E,6S,7R)-germacradien-6-ol
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ 10-
epi
-juneol
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-(2S,3R,9R)-pristinol
9α-copalyl diphosphate + H
2
O → 13
S
-vitexifolin A +
diphosphate
5-phospho-α-D-ribose 1-diphosphate + H
+
+
trans,octacis
-decaprenyl phosphate →
trans,octacis
-decaprenylphospho-β-D-ribofuranose 5-phosphate +
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-corvol ether B
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-epicubenol
H
2
O + dITP → H
+
+
diphosphate
+ dIMP
phytyl diphosphate + homogentisate + H
+
→ 2-methyl-6-phytyl-1,4-benzoquinol +
diphosphate
+ CO
2
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ cyclosativene
(+)-copalyl diphosphate + H
2
O → ent-16-a-hydroxy-kaurene +
diphosphate
2 H
+
+ 2 GTP +
bis
(molybdenum cofactor) → 2
diphosphate
+
bis
(guanylyl molybdopterin) cofactor
5 isopentenyl diphosphate + (2
E
,6
E
)-farnesyl diphosphate → 5
diphosphate
+ all-
trans
-octaprenyl diphosphate
olivetolate + geranyl diphosphate →
diphosphate
+ cannabigerolate
H
2
O + ATP → H
+
+
diphosphate
+ AMP
coenzyme A + hexanoate + ATP → hexanoyl-CoA +
diphosphate
+ AMP
H
2
O + protoheme + (2
E
,6
E
)-farnesyl diphosphate → heme
o
+
diphosphate
L-valine + (-)-jasmonate + ATP → H
+
+
diphosphate
+ (-)-jasmonoyl-L-valine + AMP
L-glutamine + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-glutamine + H
+
+
diphosphate
+ AMP
H
+
+ L-glutamate + ATP → (L-glutamyl)adenylate +
diphosphate
11 ATP + 2
N
5
-formyl-
N
5
-hydroxy-L-ornithine + 2 L-threonine + 2 L-serine + L-tyrosine + L-lysine + L-glutamate + L-2,4-diaminobutanoate + L-arginine → 11
diphosphate
+ 11 AMP + 12 H
+
+ ferribactin + H
2
O
prenyl diphosphate + genistein → isowighteone +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+
cis
-muurola-4(14),5-diene
5-hydroxyanthrotainin + geranyl diphosphate →
diphosphate
+ previridicatumtoxin
geranyl diphosphate → γ-terpinene +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-β-bulgarene
quinoxaline-2-carboxylate + H
+
+ ATP → quinoxaline-2-carboxyl adenylate +
diphosphate
coenzyme A + 4-chlorobenzoate + ATP → 4-chlorobenzoyl-coA +
diphosphate
+ AMP
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (2E,6E)-hedycaryol
N
-(3-aminopropyl)-
N
-hydroxyacetamide + ATP + citrate → (citryl)-
N
-(3-aminopropyl)-
N
-hydroxyacetamide + H
+
+
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ guaia-4,6-diene
geranylgeranyl diphosphate +
sn
-glycerol 1-phosphate → 3-(
O
-geranylgeranyl)-
sn
-glycerol 1-phosphate +
diphosphate
coenzyme A + 16-hydroxypalmitate + ATP →
diphosphate
+ 16-hydroxypalmitoyl-CoA + AMP
(+)-copalyl diphosphate → (+)-isopimara-8,15-diene +
diphosphate
all-
trans
-hexaprenyl diphosphate → β-hexaprene +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ δ-cuprenene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ α-longipinene
D-
glycero
-α-D-
manno
-heptose 1-phosphate + H
+
+ GTP → GDP-D-
glycero
-α-D-
manno
-heptose +
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate → (+)-τ-muurolol +
diphosphate
prenyl diphosphate + AMP →
N
6
-(Δ
2
-isopentenyl)-adenosine 5'-monophosphate +
diphosphate
geranyl diphosphate →
diphosphate
+ (+)-α-pinene
4,5-dehydro-L-arginine + indolmycenate + ATP → (2R,4E)-2-amino-5-({[(2S,3R)-2-hydroxy-3-(1H-indol-3-yl)butanamido]methanimidoyl}amino)pent-4-enoate + H
+
+
diphosphate
+ AMP
5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonate + CTP →
diphosphate
+ CMP-5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-D-galacto-non-2-ulosonate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (
E
,
E
)-α-farnesene
geranylgeranyl diphosphate → rhizathalene A +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-α-barbatene
D-ornithine + ATP + citrate → H
+
+ 3-[(2-aminopentan-5-oylcarbamoyl)methyl]-3-hydroxybutanoate +
diphosphate
+ AMP
(
R
)-4'-phosphopantothenate + L-cysteine + ATP → (R)-4'-phosphopantothenoyl-L-cysteine + H
+
+
diphosphate
+ AMP
L-alanine + ATP + fumiquinazoline F-indoline-2',3'-diol → H
2
O + H
+
+
diphosphate
+ AMP + fumiquinazoline A
prenyl diphosphate + phlorisovalerophenone → 4-prenylphlorisovalerophenone + H
+
+
diphosphate
L-phenylalanine + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-phenylalanine + H
+
+
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (2S,3R,6S,9S)-(-)-protoillud-7-ene
geranylgeranyl diphosphate → (
R
)-cembrene A +
diphosphate
N-methylethanolamine phosphate + H
+
+ CTP →
diphosphate
+ CDP-N-methylethanolamine
coenzyme A + 5-aminolevulinate + ATP → 5-aminolevulinyl-CoA +
diphosphate
+ AMP
H
2
O + dGTP → H
+
+
diphosphate
+ dGMP
prenyl diphosphate + 4-prenylphlorisovalerophenone → deoxyhumulone +
diphosphate
(13
E
)-8α-hydroxylabd-13-en-15-yl diphosphate + H
2
O + a reduced electron donor → an oxidized electron donor + labd-13-en-8α-,15 diol +
diphosphate
H
2
O + geranylgeranyl diphosphate → hydropyrenol +
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-patchoulol
H
+
+ geranylgeranyl diphosphate + chlorophyllide
a
→
diphosphate
+ geranylgeranyl chlorophyll
a
H
2
O + prenyl diphosphate → prenol +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-α-amorphene
coenzyme A + pentanoate + ATP → pentanoyl-CoA +
diphosphate
+ AMP
pyridin-1-ium-3-carboxylate-5-thiocarboxylate mononucleotide + H
+
+ ATP → 1-(5-
O
-phospho-β-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium-3-carbonyl adenylate +
diphosphate
L-tyrosine + L-arginine + ATP → L-tyrosyl-L-arginine + H
+
+
diphosphate
+ AMP
(13
E
)-8α-hydroxylabd-13-en-15-yl diphosphate → cis-abienol +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-amorpha-4,11-diene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ aristolochene
prenyl diphosphate + L-tryptophan → 4-(3-methylbut-2-enyl)-L-tryptophan +
diphosphate
N
3
-decanoyl-
N
3
-hydroxy-1,3-diaminopropane + ATP + citrate →
N
1
-citryl-
N
3
-decanoyl-
N
3
-hydroxy-1,3-diaminopropane + H
+
+
diphosphate
+ AMP
1,4-dihydroxy-2-naphthoate + all-
trans
-octaprenyl diphosphate → 2-demethylmenaquinone-
8
+ H
+
+
diphosphate
+ CO
2
2 prenyl diphosphate + paxilline → 2
diphosphate
+ 21,22-diprenylpaxilline
L-2,3-diaminopropanoate + ATP + citrate → 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + H
+
+
diphosphate
+ AMP
2-hydroxy-dATP + H
2
O → 2-hydroxy-dAMP + H
+
+
diphosphate
L-leucine + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-leucine + H
+
+
diphosphate
+ AMP
desferrioxamine G
1
+ ATP → desferrioxamine E + H
+
+
diphosphate
+ AMP
O
-citryl-ethanolamine + L-2,4-diaminobutanoate + ATP → diaminobutyryl-citryl-ethanolamine + H
+
+
diphosphate
+ AMP
(+)-copalyl diphosphate → (12E)-labda-8(17),12,14-triene +
diphosphate
geranylgeranyl diphosphate →
ent
-kaurene +
diphosphate
molybdopterin + H
+
+ ATP → molybdopterin adenine dinucleotide +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ α-selinene
coenzyme A + 3,24-dioxo-cholest-4-en-26-oate + ATP → 3,24-dioxocholest-4-en-26-oyl-CoA +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-β-caryophyllene
all-trans
-lycopene + H
2
O + prenyl diphosphate → dihydroisopentenyldehydrorhodopin +
diphosphate
coenzyme A + 4-oxopentanoate + ATP → 4-oxopentanoyl-CoA +
diphosphate
+ AMP
H
+
+ ATP + α-D-glucopyranose 1-phosphate → ADP-α-D-glucose +
diphosphate
ochrindole D + prenyl diphosphate → terrequinone A +
diphosphate
5,7-dihydroxy-4,6-dimethylphthalide + (2
E
,6
E
)-farnesyl diphosphate → farnesyl-5,7-dihydroxy-4,6-dimethylphthalide +
diphosphate
2 anthranilate + 3 ATP + L-tryptophan → 3
diphosphate
+ 3 AMP + H
2
O + H
+
+ asperlicin D
2 anthranilate + 3 ATP + L-tryptophan → 3
diphosphate
+ 3 AMP + H
2
O + H
+
+ asperlicin C
H
2
O +
di-trans, poly-cis
-polyprenyl diphosphate (C
80
) →
di-trans, poly-cis
-polyprenol (C
80
) +
diphosphate
3 glycine + 3
N
5
-acetyl-
N
5
-hydroxy-L-ornithine + 3 ATP + Fe
3+
→ 3 H
2
O + 3
diphosphate
+ 3 AMP + 6 H
+
+ ferrichrome
2 ATP + anthranilate +
S
-adenosyl-L-methionine + L-phenylalanine → 2 H
+
+ 2
diphosphate
+ 2 AMP +
S
-adenosyl-L-homocysteine + cyclopeptine
12-ethyl-8-isobutylbacteriochlorophyllide
c
+ H
+
+ (2
E
,6
E
)-farnesyl diphosphate → 12-ethyl-8-isobutylbacteriochlorophyll
c
+
diphosphate
H
2
O + geranyl diphosphate → sabinene hydrate +
diphosphate
H
+
+ MoO
2
-molybdopterin cofactor + CTP → cytidylyl molybdenum cofactor +
diphosphate
coenzyme A + (3
R
)-β-phenylalanine + ATP → (3
R
)-3-amino-3-phenylpropanoyl-CoA +
diphosphate
+ AMP
coenzyme A + H
+
+
cis
-vaccenate + ATP → H
+
+
cis
-vaccenoyl-CoA +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-5-epieremophilene
pre-putrebactin + ATP → putrebactin + H
+
+
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-germacrene D
diphosphate
+ XMP ← 5-phospho-α-D-ribose 1-diphosphate + xanthine
geranyl diphosphate + 3-[(
Z
)-2-isocyanoethenyl]-1
H
-indole →
diphosphate
+ 3-geranyl-3-[(
Z
)-2-isocyanoethenyl]-1H-indole
H
2
O + 8-oxo-GTP → H
+
+
diphosphate
+ 8-oxo-GMP
N
1
-citryl-
N
3
-dec-2-enoyl-
N
3
-hydroxy-1,3-diaminopropane + L-2,4-diaminobutanoate + ATP →
N
5
-2,4-diaminobutanoate-
N
1
-citryl-
N
3
-dec-2-enoyl-
N
3
-hydroxy-1,3-diaminopropane + H
+
+
diphosphate
+ AMP
2-amino-3-hydroxycyclopent-2-enone + 2,4,6-octatrienoate + ATP → 2,4,6-octatrienyl-2-amino-3-hydroxycyclopent-2-enone +
diphosphate
+ AMP
(+)-copalyl diphosphate + H
2
O → nezukol +
diphosphate
(-)-
ent
-copalyl diphosphate →
ent
-pimara--9(11),15-diene +
diphosphate
1,4-dihydroxy-2-naphthoate + H
+
+ all-
trans
-tridecaprenyl diphosphate → demethylmenaquinol-13 +
diphosphate
+ CO
2
2
N
-hydroxy-
N
-succinylcadaverine +
N
-hydroxy-
N
-acetylcadaverine + ATP → H
2
O + desferrioxamine B + H
+
+
diphosphate
+ AMP
β-alanine + (R)-pantoate + ATP → (
R
)-pantothenate + H
+
+
diphosphate
+ AMP
4 isopentenyl diphosphate + (2
E
,6
E
)-farnesyl diphosphate → 4
diphosphate
+ all-
trans
-heptaprenyl diphosphate
(2
Z
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-γ-cadinene
L-isoleucine + (-)-jasmonate + ATP → H
+
+ (+)-7-
epi
-jasmonoyl-L-isoleucine +
diphosphate
+ AMP
2-hydroxyethylphosphonate + CTP → cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} +
diphosphate
coenzyme A + arachidonate + ATP →
diphosphate
+ AMP + arachidonoyl-CoA
H
2
O + carbamoyl phosphate + kanamycin B + ATP → H
+
+
diphosphate
+ phosphate + 6''-
O
-carbamoylkanamycin B + AMP
(+)-copalyl diphosphate → sclarene +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ sesquithujene
7 isopentenyl diphosphate + (2
Z
,6
E
)-farnesyl diphosphate → 7
diphosphate
+ mono-
trans
,octa-
cis
-decaprenyl diphosphate
L-tyrosine + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-tyrosine + H
+
+
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-β-cadinene
prenyl diphosphate + dehydrohistidyltryptophyldiketopiperazine →
diphosphate
+ roquefortine C
prenyl diphosphate + genistein → lupiwighteone +
diphosphate
L-glutamate + 4-hydroxybenzoate + ATP → H
+
+
diphosphate
+ AMP +
N
-(4-hydroxybenzoyl)-L-glutamate
H
2
O + geranylgeranyl diphosphate → aphidicolan-16β-ol +
diphosphate
3 ATP + anthranilate + L-tryptophan + L-alanine → 2 H
+
+ 3
diphosphate
+ 3 AMP + H
2
O + fumiquinazoline F
N
5
-2,4-diaminobutanoate-
N
1
-citryl-
N
3
-dec-2-enoyl-
N
3
-hydroxy-1,3-diaminopropane + 2-oxoglutarate + ATP → baumannoferrin A + H
+
+
diphosphate
+ AMP
2-amino-4-phosphonobutanoate + H
+
+ CTP → CMP-5'-3-(aminopropyl)phosphonate +
diphosphate
+ CO
2
H
+
+ geranylgeranyl diphosphate + bacteriochlorophyllide
a
→ geranylgeranyl bacteriochlorophyllide
a
+
diphosphate
coenzyme A + 18-hydroxyoleate + ATP → 18-hydroxyoleoyl-CoA +
diphosphate
+ AMP
tuberculosinyl diphosphate + H
2
O → (13
S
)-isotuberculosinol +
diphosphate
H
2
O + 7,8-dihydroneopterin 3'-triphosphate → 7,8-dihydroneopterin 3'-phosphate + H
+
+
diphosphate
(13
E
)-8α-hydroxylabd-13-en-15-yl diphosphate → manoyl oxide +
diphosphate
L-tyrosinal + NADP
+
+
diphosphate
+ AMP ← NADPH + H
+
+ L-tyrosine + ATP
H
2
O + (2
E
,6
E
)-farnesyl diphosphate → presilphiperfolan-8β-ol +
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ 7-
epi
-α-eudesmol
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ α-eudesmol
2 ATP + L-tryptophan + L-histidine → 2 H
+
+ 2
diphosphate
+ 2 AMP + histidyltryptophyldiketopiperazine
coenzyme A + 18-hydroxystearate + ATP → 18-hydroxystearoyl-CoA +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-γ-cadinene
H
2
O + carbamoyl phosphate + ATP → (
O
-carbamoyl)adenylate +
diphosphate
+ phosphate
L-isoleucine + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-isoleucine + H
+
+
diphosphate
+ AMP
prenyl diphosphate + 4-prenylphlorisobutyrophenone → deoxycohumulone +
diphosphate
8 isopentenyl diphosphate + (2
E
,6
E
)-farnesyl diphosphate → 8
diphosphate
+
di-trans,octa-cis
-undecaprenyl diphosphate
coenzyme A + ATP + 4-hydroxybutanoate → 4-hydroxybutanoyl-CoA +
diphosphate
+ AMP
L-glutamate + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-glutamate + H
+
+
diphosphate
+ AMP
5-hydroxy-CTP + H
2
O → 5-hydroxy-CMP + H
+
+
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ β-sesquiphellandrene
3-hydroxyquinaldate + H
+
+ ATP → 3-hydroxyquinaldate adenylate +
diphosphate
L-aspartate + O-ureido-L-homoserine + ATP → H
+
+
diphosphate
+ AMP + canavaninosuccinate
ppGpp + H
2
O → H
+
+
diphosphate
+ GDP
4-hydroxybenzoate +
all-trans
-nonaprenyl diphosphate → 3-nonaprenyl-4-hydroxybenzoate +
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate → (
2E,6E
)-farnesol +
diphosphate
L-aspartate + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-aspartate + H
+
+
diphosphate
+ AMP
(3
1
R)-8-ethyl-12-methylbacteriochlorophyllide
c
+ H
+
+ (2
E
,6
E
)-farnesyl diphosphate → (3
1
R)-8-ethyl-12-methylbacteriochlorophyll
c
+
diphosphate
geranylgeranyl diphosphate → taxa-4,11-diene +
diphosphate
2 3-phenyl-2-oxopropanoate + 2 ATP + H
2
O → 2
diphosphate
+ 2 AMP + (-)-microperfuranone + CO
2
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ longiborneol
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (2Z,6E)-hedycaryol
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-
epi
-α-bisabolol
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ kunzeaol
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ α-copaene
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ 5-hydroxy-α-gurjunene
H
2
O + 3'-amino-3'-deoxyATP → 2 H
+
+
diphosphate
+ 3'-amino-3'-deoxyAMP
H
2
O + (2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ τ-cadinol
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-β-cubebene
5-phospho-α-D-ribose 1-diphosphate + H
+
+ 4-aminobenzoate → 4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate +
diphosphate
+ CO
2
coenzyme A + 5-hydroxyferulate + ATP → 5-hydroxy-feruloyl-CoA +
diphosphate
+ AMP
3-hydroxy-4-methylanthranilate + H
+
+ ATP → 3-hydroxy-4-methylanthranilyl-adenylate +
diphosphate
coenzyme A + 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate + ATP → 3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-octanoyl-CoA +
diphosphate
+ AMP
H
2
O + geranylfarnesyl diphosphate → sesterfisherol +
diphosphate
H
2
O + carbamoyl phosphate + tobramycin + ATP → H
+
+
diphosphate
+ phosphate + nebramycin 5' + AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-eremophilene
geranyl diphosphate → (
E
)-β-ocimene +
diphosphate
H
2
O + GTP → cyclic pyranopterin phosphate +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (
Z,E
)-germacrene B
prenyl diphosphate + fumigaclavine A →
diphosphate
+ fumigaclavine C
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-germacrene D
(-)-
ent
-copalyl diphosphate →
ent
-sandaracopimaradiene +
diphosphate
coenzyme A + pristanate + ATP → pristanoyl-CoA +
diphosphate
+ AMP
H
+
+ 1,4-dihydroxy-6-naphthoate + all-
trans
-octaprenyl diphosphate → demethylmenaquinol-8 +
diphosphate
+ CO
2
geranylgeranyl diphosphate → fusicocca-2,10(14)-diene +
diphosphate
(-)-
ent
-copalyl diphosphate →
ent
-cassa-12,15-diene +
diphosphate
N
-acetyl-α-D-galactosamine 1-phosphate + H
+
+ UTP → UDP-
N
-acetyl-α-D-galactosamine +
diphosphate
prenyl diphosphate + ADP →
N
6
-(Δ
2
-isopentenyl)-adenosine 5'-diphosphate +
diphosphate
acetoacetyl-CoA + L-isoleucine + ATP → coenzyme A + tenuazonic acid + H
+
+
diphosphate
+ AMP
prenyl diphosphate + 12α,13α-dihydroxyfumitremorgin C → fumitremorgin B +
diphosphate
5-phospho-α-D-ribose 1-diphosphate + [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol → [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl 5-phosphate]-D-ribitol +
diphosphate
glycerol 2-phosphate + H
+
+ CTP → CDP-2-glycerol +
diphosphate
stearate + H
+
+ ATP → (stearoyl)adenylate +
diphosphate
2-[(2-aminoethylcarbamoyl)methyl]-2-hydroxybutanedioate + L-2,3-diaminopropanoate + ATP → 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + H
+
+
diphosphate
+ AMP
geranyl diphosphate → (
4R
)-limonene +
diphosphate
geranylfarnesyl diphosphate → β-geranylfarnesene +
diphosphate
coenzyme A + ATP + α,ω-9
Z
-octadecenedioate → ω-carboxy-(9
Z
)-octadec-9-enoyl-CoA +
diphosphate
+ AMP
geranylgeranyl diphosphate → tsukubadiene +
diphosphate
coenzyme A + palmitoleate + H
+
+ ATP → H
+
+ palmitoleoyl-CoA +
diphosphate
+ AMP
H
2
O + geranyl diphosphate → 1,8-cineole +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-5-
epi
-aristolochene
coenzyme A + (25S)-3-oxocholest-4-en-26-oate + ATP → (25S)-3-oxocholest-4-en-26-oyl-CoA +
diphosphate
+ AMP
2 prenyl diphosphate + terpendole C → 2
diphosphate
+ 20,21-diprenylterpendole C
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-γ-amorphene
H
2
O + m
7
GTP →
N
7
-methylguanosine 5'-phosphate + H
+
+
diphosphate
coenzyme A + 3-pentenoate + ATP → 3-pentenoyl-CoA +
diphosphate
+ AMP
L-phenylalanine + (-)-jasmonate + ATP → H
+
+ (-)-jasmonoyl-L-phenylalanine +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-α-cuprenene
benzaldehyde + NADP
+
+
diphosphate
+ AMP ← NADPH + H
+
+ ATP + benzoate
3 ATP + H
+
→ 2
diphosphate
+ pppA2'p5'A2'p5'A
2 prenyl diphosphate → chrysanthemyl diphosphate +
diphosphate
2 ATP + H
+
→ P
1
,P
4
-
bis
(5'-adenosyl) tetraphosphate +
diphosphate
H
2
O +
N
-3-fumaroyl-L-2,3-diaminopropanoate + L-glutamine + ATP →
N
-3-fumaramoyl-L-2,3-diaminopropanoate + H
+
+ L-glutamate +
diphosphate
+ AMP
H
+
+ roseoflavin 5'-phosphate + ATP →
diphosphate
+ roseoflavin adenine dinucleotide
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ β-acoradiene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-β-elemene
geranyl diphosphate → terpinolene +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ α-cubebene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ α-zingiberene
H
2
O + XTP → H
+
+
diphosphate
+ XMP
2 phytyl diphosphate + NADPH + H
+
→ 2
diphosphate
+ (14
E
,18
E
)-lycopadiene + NADP
+
2 L-serine + 3 methylglutaconyl hydroxy ornithine + 3 ATP + glycine + Fe
3+
→ 3 H
2
O + 3 H
+
+ 3
diphosphate
+ 3 AMP + ferrichrome A
ethanolamine + ATP + citrate →
O
-citryl-ethanolamine +
diphosphate
+ AMP
palmitate + H
+
+ ATP → (palmitoyl)adenylate +
diphosphate
diaminobutyryl-citryl-ethanolamino-α-ketoglutarate + 2-oxoglutarate + ATP → H
+
+ achromobactin +
diphosphate
+ AMP
coenzyme A + acetoacetate + ATP → acetoacetyl-CoA +
diphosphate
+ AMP
10 isopentenyl diphosphate + (2
E
,6
E
)-farnesyl diphosphate → 10
diphosphate
+ all-
trans
-tridecaprenyl diphosphate
2'-hydroxygenistein + prenyl diphosphate → phaseoluteone +
diphosphate
phosphonoformate + CTP → CMP-5'-phosphonoformate +
diphosphate
(+)-copalyl diphosphate → levopimaradiene +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (
E,E
)-germacrene B
2 ATP + anthranilate +
S
-adenosyl-L-methionine +
O
-methyl-
L
-tyrosine → 2 H
+
+ 2
diphosphate
+ 2 AMP +
S
-adenosyl-L-homocysteine + 4'-methoxycyclopeptine
4-methylene-L-glutamate + ammonium + ATP → 4-methylene-L-glutamine + H
+
+
diphosphate
+ AMP
N
1
-citryl-
N
6
-acetyl-
N
6
-hydroxy-L-lysine +
N
6
-acetyl-
N
6
-hydroxy-L-lysine + ATP → aerobactin + H
+
+
diphosphate
+ AMP
3-amino-4-hydroxybenzoate + H
+
+ ATP → 3-amino-4-hydroxybenzoate-adenylate +
diphosphate
4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H
+
+ 4-methyl-5-(2-phosphooxyethyl)thiazole → thiamine phosphate +
diphosphate
coenzyme A + 2-furoate + ATP → 2-furoyl-CoA +
diphosphate
+ AMP
coenzyme A + isovalerate + ATP → isovaleryl-CoA +
diphosphate
+ AMP
H
2
O + geranylgeranyl diphosphate → (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol +
diphosphate
3 H
2
O + GTP → 2 H
+
+ 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate +
diphosphate
(3
1
R)-8-ethyl-12-methylbacteriochlorophyllide
e
+ H
+
+ (2
E
,6
E
)-farnesyl diphosphate → (3
1
R)-8-ethyl-12-methylbacteriochlorophyll
e
+
diphosphate
coenzyme A + pimelate + ATP → pimeloyl-CoA +
diphosphate
+ AMP
H
2
O + α-D-ribose-1-(methyl)phosphonate-5-triphosphate → α-D-ribose-1-methylphosphonate 5-phosphate + H
+
+
diphosphate
coenzyme A + malonamate + ATP → malonamoyl-CoA +
diphosphate
+ AMP
coenzyme A + 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + ATP → 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA +
diphosphate
+ AMP
prenyl diphosphate + deoxyhumulone + H
+
+ geranyl diphosphate → 2
diphosphate
+ adhyperforin
H
2
O + ITP → H
+
+
diphosphate
+ IMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ selina-4(15),7(11)-diene
geranylgeranyl diphosphate → isoelisabethatriene +
diphosphate
N
-3-fumaramoyl-L-2,3-diaminopropanoate + H
+
+ ATP →
N
-3-fumaramoyl-(S)-2,3-diaminopropanoyl-adenylate +
diphosphate
2 H
+
+ coenzyme A + 3-oxo-24-ethyl-cholest-4-en-26-oate + ATP → 3-oxo-24-ethyl-cholest-4-en-26-oyl-CoA +
diphosphate
+ AMP
coenzyme A + oleate + ATP → oleoyl-CoA +
diphosphate
+ AMP
H
2
O + L-aspartate + L-glutamine + ATP → H
+
+ L-glutamate + L-asparagine +
diphosphate
+ AMP
H
2
O + ATP + cob(I)inamide →
diphosphate
+ phosphate + adenosylcobinamide
coenzyme A + marinolic acid C + ATP → marinoloyl-CoA C +
diphosphate
+ AMP
GTP +
aldehydo
-D-arabinose 5-phosphate → GDP-D-arabinose +
diphosphate
a carboxylate + coenzyme A + ATP →
diphosphate
+ AMP + an acyl-CoA
isopentenyl diphosphate + geranyl diphosphate →
diphosphate
+ (2
Z
,6
E
)-farnesyl diphosphate
9α-copalyl diphosphate →
syn
-labda-8(17),12
E
,14-triene +
diphosphate
tuberculosinyl diphosphate + H
2
O → (13
R
)-isotuberculosinol +
diphosphate
(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate + coenzyme A + ATP → (5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA +
diphosphate
+ AMP
coenzyme A + butanoate + ATP → butanoyl-CoA +
diphosphate
+ AMP
2-C-methyl-D-erythritol 4-phosphate + H
+
+ CTP →
diphosphate
+ 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ 7-
epi
-α-selinene
(2R,3S)-2-dodecyl-3-hydroxyhexadecanoate + ATP → 3-dodecyl-4-tridecyloxetan-2-one +
diphosphate
+ AMP
geranyl diphosphate → (-)-camphene +
diphosphate
tuberculosinyl diphosphate + H
2
O → tuberculosinol +
diphosphate
L-valine + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-valine + H
+
+
diphosphate
+ AMP
poly(ribitol phosphate) + ATP + D-alanine → O-D-alanyl-poly(ribitol phosphate) + H
+
+
diphosphate
+ AMP
coenzyme A + (25R)-3-oxocholest-4-en-26-oate + ATP → (25R)-3-oxocholest-4-en-26-oyl-CoA +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ bicyclogermacrene
H
+
+ GTP + α-D-mannose 1-phosphate → GDP-α-D-mannose +
diphosphate
coenzyme A + 3-(methylsulfanyl)propanoate + ATP → 3-(methylsulfanyl)propanoyl-CoA +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-α-muurolene
coenzyme A + biotin + ATP → biotinyl-CoA +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-vetispiradiene
(3
1
R)-8,12-diethylbacteriochlorophyllide
e
+ H
+
+ (2
E
,6
E
)-farnesyl diphosphate → (3
1
R)-8,12-diethylbacteriochlorophyll
e
+
diphosphate
9α-copalyl diphosphate → 9β-stemod-13(17)-ene +
diphosphate
geranyl diphosphate → β-thujene +
diphosphate
coenzyme A +
trans
-caffeate + ATP →
trans
-caffeoyl-CoA +
diphosphate
+ AMP
3-dimethylallyl-4-hydroxybenzoate + 3-amino-4,7-dihydroxy-coumarin + ATP → 8-demethylnovobiocic acid + H
+
+
diphosphate
+ AMP
pre-bisucaberin + ATP → bisucaberin + H
+
+
diphosphate
+ AMP
(6Z,9Z,12Z,15Z)-3-hydroxy-2-[(2Z,5Z,8Z,11Z)-tetradeca-2,5,8,11-tetraen-1-yl]octadeca-6,9,12,15-tetraenoate + ATP → 3-[(3Z,6Z,9Z,12Z)-pentadeca-3,6,9,12-tetraen-1-yl]-4-[(2Z,5Z,8Z,11Z)-tetradeca-2,5,8,11-tetraen-1-yl]oxetan-2-one +
diphosphate
+ AMP
H
2
O + carbamoyl phosphate + kanamycin A + ATP → H
+
+
diphosphate
+ phosphate + 6''-
O
-carbamoylkanamycin A + AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ β-ylangene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (
E
)-α-bisabolene
3 isopentenyl diphosphate + geranylgeranyl diphosphate → 3
diphosphate
+ all-
trans
-heptaprenyl diphosphate
H
2
O + malonyl-CoA + L-glutamine + ATP → malonamoyl-CoA + H
+
+ L-glutamate +
diphosphate
+ AMP
coenzyme A + 7-hydroxylaurate + ATP → 7-hydroxylauroyl-CoA +
diphosphate
+ AMP
phytyl diphosphate + 2-carboxy-1,4-naphthoquinone + H
+
→ demethylphylloquinone +
diphosphate
+ CO
2
coenzyme A + chenodeoxycholate + ATP → chenodeoxycholoyl-CoA +
diphosphate
+ AMP
7 isopentenyl diphosphate + (2
E
,6
E
)-farnesyl diphosphate → 7
diphosphate
+ all-
trans
-decaprenyl diphosphate
H
+
+ D-xylulose 5-phosphate + CTP →
diphosphate
+ CDP-D-xylulose
O
-phosphoethanolamine + H
+
+ CTP → CDP-ethanolamine +
diphosphate
α-ketoglutaryl-diaminobutyryl-citryl-ethanolamine + 2-oxoglutarate + ATP → H
+
+ achromobactin +
diphosphate
+ AMP
[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate + 4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate → [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate +
diphosphate
geranylgeranyl diphosphate → phomopsene +
diphosphate
2 GTP → 2
diphosphate
+ cyclic di-3',5'-guanylate
isopentenyl diphosphate + all-
trans
-heptaprenyl diphosphate → all-
trans
-octaprenyl diphosphate +
diphosphate
(+)-copalyl diphosphate → pimara-8(14),15-diene +
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate → (3
S
,6
E
)-nerolidol +
diphosphate
9α-copalyl diphosphate → stemar-13-ene +
diphosphate
D-firefly luciferin + H
+
+ ATP → (D-firefly luciferyl)adenylate +
diphosphate
(-)-
ent
-copalyl diphosphate →
ent
-kaurene +
diphosphate
2,3-dihydroxybenzoate + H
+
+ ATP → (2,3-dihydroxybenzoyl)adenylate +
diphosphate
H
2
O + (
E
)-2-methylgeranyl diphosphate → 2-methylisoborneol +
diphosphate
geranylgeranyl diphosphate → (3
E
,7
E
)-dolathalia-3,7,11-triene +
diphosphate
7 isopentenyl diphosphate + geranyl diphosphate → 7
diphosphate
+
all-trans
-nonaprenyl diphosphate
coenzyme A + (25
R
)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate + ATP → (25
R
)-3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA +
diphosphate
+ AMP
1,4-dihydroxy-2-naphthoate + H
+
+ all-
trans
-decaprenyl diphosphate → demethylmenaquinol-10 +
diphosphate
+ CO
2
isopentenyl diphosphate + all-
trans
-hexaprenyl diphosphate → all-
trans
-heptaprenyl diphosphate +
diphosphate
homogentisate + H
+
+ geranylgeranyl diphosphate → 2-methyl-6-geranylgeranyl-1,4-benzoquinol +
diphosphate
+ CO
2
prenyl diphosphate + phlormethylbutanophenone → 4-prenylphlormethylbutanophenone + H
+
+
diphosphate
an oxidized electron donor + nonaflavuxanthin + H
2
O + prenyl diphosphate → flavuxanthin + a reduced electron donor +
diphosphate
N
1
-(3,4-dihydroxybenzoyl)-
N
8
-citryl-spermidine + spermidine + ATP →
N
1
-(3,4-dihydroxybenzoyl)-
N
8
,
N
'
8
-citryl-bis(spermidine) + H
+
+
diphosphate
+ AMP
7 isopentenyl diphosphate + geranylgeranyl diphosphate → 7
diphosphate
+ tri-
trans
,hepta-
cis
-undecaprenyl diphosphate
N
-acetyl-α-D-glucosamine 1-phosphate + H
+
+ dTTP → dTDP-N-acetyl-α-D-glucosamine +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ pentalenene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-α-gurjunene
[5-(aminomethyl)furan-3-yl]methyl diphosphate + γ-glutamyltyramine → (4-{4-[2-(γ-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ α-himachalene
(2R,3S)-2-hexyl-3-hydroxydecanoate + ATP → 3-hexyl-4-septyloxetan-2-one +
diphosphate
+ AMP
2 ATP +
S
-adenosyl-L-methionine + (
S
)-1-pyrroline-5-carboxylate + L-arginine → 2 H
+
+ 2
diphosphate
+ 2 AMP + H
2
O +
S
-adenosyl-L-homocysteine + peramine
(13
E
)-8α-hydroxylabd-13-en-15-yl diphosphate + H
2
O → sclareol +
diphosphate
spermidine +
N
-citryl-spermidine + ATP →
N
8
,
N
'
8
-citryl-bis(spermidine) + H
+
+
diphosphate
+ AMP
geranyl diphosphate → β-myrcene +
diphosphate
prenyl diphosphate + verruculogen → fumitremorgin A +
diphosphate
(citryl)-
N
-(3-aminopropyl)-
N
-hydroxyacetamide +
N
-(3-aminopropyl)-
N
-hydroxyacetamide + ATP → schizokinen + H
+
+
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ trichodiene
3 H
+
+ phytyl diphosphate + 1,4-dihydroxy-2-naphthoate → demethylphylloquinol +
diphosphate
+ CO
2
all-
trans
-heptaprenyl diphosphate + 4-hydroxybenzoate → 3-heptaprenyl-4-hydroxybenzoate +
diphosphate
L-glutamate + ATP + benzoate → H
+
+
diphosphate
+ AMP +
N
-benzoyl-L-glutamate
H
2
O + geranylgeranyl diphosphate → (3
E
,7
E
)-dolabella-3,7-dien-18-ol +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ seli-3,7(11)-diene
1,4-dihydroxy-2-naphthoate + all-
trans
-heptaprenyl diphosphate → 2-demethylmenaquinone-
7
+ H
+
+
diphosphate
+ CO
2
(-)-
ent
-copalyl diphosphate →
ent
-atiserene +
diphosphate
coenzyme A + isobutanoate + ATP → isobutanoyl-CoA +
diphosphate
+ AMP
N
3
-dec-2-enoyl-
N
3
-hydroxy-1,3-diaminopropane + ATP + citrate →
N
1
-citryl-
N
3
-dec-2-enoyl-
N
3
-hydroxy-1,3-diaminopropane + H
+
+
diphosphate
+ AMP
neryl diphosphate → (4
S
)-limonene +
diphosphate
C30 botryococcene + NADP
+
+
diphosphate
← NADPH + presqualene diphosphate + H
+
geranyl diphosphate → (4
S
)-limonene +
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate → 4-
epi
-cubebol +
diphosphate
2-keto-3-deoxy-D-
glycero
-D-
galacto
-nononate + CTP →
diphosphate
+ CMP-3-deoxy-D-
glycero
-D-
galacto
-non-2-ulopyranosonate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-
exo
-α-bergamotene
1,4-dihydroxy-2-naphthoate + prenyl diphosphate →
diphosphate
+ alizarin
coenzyme A + (15
Z
)-tetracosenoate + ATP →
diphosphate
+ (
Z
)-15-tetracosenoyl-CoA + AMP
(-)-
ent
-copalyl diphosphate + H
2
O →
ent
-manool +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ seychellene
H
2
O + 1-(5-phospho-β-D-ribosyl)-ATP → H
+
+ 1-(5-phospho-β-D-ribosyl)-AMP +
diphosphate
H
2
O + (-)-bornyl-diphosphate →
diphosphate
+ (-)-borneol
geranylgeranyl diphosphate + (1
S
,2
R
)-1-C-(indol-3-yl)glycerol 3-phosphate → 3-geranylgeranylindole + D-glyceraldehyde 3-phosphate +
diphosphate
protocatechuate + H
+
+ ATP → (3,4-dihydroxybenzoate)adenylate +
diphosphate
H
2
O + geranylgeranyl diphosphate → (R)-nephthenol +
diphosphate
5-phospho-α-D-ribose 1-diphosphate + H
2
O →
diphosphate
+
aldehydo
-D-ribose 5-phosphate
H
2
O + 8-oxo-dGTP → H
+
+
diphosphate
+ 8-oxo-dGMP
menadiol + geranylgeranyl diphosphate → menaquinol-
4
+
diphosphate
2 geranylgeranyl diphosphate → 2
diphosphate
+ 15-
cis
-phytoene
arachidate + H
+
+ ATP → (arachidoyl)adenylate +
diphosphate
H
+
+ 2,3-bis-
O
-(geranylgeranyl)-
sn
-glycerol 1-phosphate + CTP → unsaturated CDP-archaeol +
diphosphate
salicylate + H
+
+ ATP → (salicyl)adenylate +
diphosphate
H
+
+ L-proline + ATP → (L-prolyl)adenylate +
diphosphate
H
+
+ 4-hydroxybenzoate + ATP →
diphosphate
+ 4-hydroxybenzoyl-adenylate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-valencene
2 H
2
O + dCTP → ammonium +
diphosphate
+ dUMP
L-tryptophan + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-tryptophan + H
+
+
diphosphate
+ AMP
1,4-dihydroxy-2-naphthoate + H
+
+ geranylgeranyl diphosphate → demethylmenaquinol-4 +
diphosphate
+ CO
2
geranyl diphosphate → (+)-α-thujene +
diphosphate
2 H
+
+ selenate + ATP → adenosine 5'-phosphoselenate +
diphosphate
(-)-
ent
-copalyl diphosphate → dolabradiene +
diphosphate
H
+
+ L-arginine + ATP → (L-arginyl)adenylate +
diphosphate
GTP + ATP →
diphosphate
+ pppGp(2'-5')A
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ β-cedrene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ rotundene
N
-acetyl-β-neuraminate + CTP →
diphosphate
+ CMP-
N
-acetyl-β-neuraminate
prenyl diphosphate + brevianamide F → deoxybrevianamide E +
diphosphate
geranyl diphosphate → (
Z
)-β-ocimene +
diphosphate
1,4-dihydroxy-2-naphthoate + H
+
+ all-
trans
-octaprenyl diphosphate → demethylmenaquinol-8 +
diphosphate
+ CO
2
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ viridiflorene
coenzyme A + malonate + ATP → malonyl-CoA +
diphosphate
+ AMP
L-threonine + ATP → L-thr-AMP +
diphosphate
2 L-aspartate + 6 Mg
2+
+ 6 ATP + L-HPG + trans-2,3-epoxyhexanone + L-tryptophan + L-threonine + L-serine → 6
diphosphate
+ 6 ADP + 6 CO
2
+ trans-2,3-epoxyhexanone-ser-thr-D-Trp-asp-asp-D-HPG-S-cdaPS1
coenzyme A + laurate + ATP → lauroyl-CoA +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ Δ
2,4
-protoilludene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ α-patchoulene
prenyl diphosphate + 6-hydroxy-deoxybrevianamide E →
diphosphate
+ notoamide S
(13
E
)-8α-hydroxylabd-13-en-15-yl diphosphate + H
2
O → labdenediol +
diphosphate
coenzyme A + 2-naphthoate + ATP → 2-naphthoyl-CoA +
diphosphate
+ AMP
L-serine + ATP + citrate →
O
-citryl-L-serine +
diphosphate
+ AMP
(8
S
)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate → cyclic pyranopterin phosphate +
diphosphate
prenyl diphosphate + deoxyhumulone →
diphosphate
+ lupulone
2 H
+
+ 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2-[(2
R
,5
Z
)-2-carboxy-4-methylthiazol-5(2
H
)-ylidene]ethyl phosphate → thiamine phosphate +
diphosphate
+ CO
2
isopentenyl diphosphate + (2
E
,6
E
)-farnesyl diphosphate → 2-
cis
,6-
trans
,10-
trans
-geranylgeranyl diphosphate +
diphosphate
(+)-copalyl diphosphate → neoabietadiene +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-γ-bulgarene
H
2
O + (2
E
,6
E
)-farnesyl diphosphate → cubebol +
diphosphate
H
2
O + geranylgeranyl diphosphate → cyclooctat-9-en-7-ol +
diphosphate
ent
-8α-hydroxylabd-13-en-15-yl diphosphate →
ent
-13-
epi
-manoyl oxide +
diphosphate
L-alanine + (-)-jasmonate + ATP → (+)-7-
epi
-jasmonoyl-L-alanine + H
+
+
diphosphate
+ AMP
coenzyme A + L-carnitine + ATP → L-carnitinyl-CoA +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate → (-)-δ-cadinene +
diphosphate
diphosphate
+ 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide ← 5-phospho-α-D-ribose 1-diphosphate + 5-amino-4-imidazolecarboxyamide
12-ethyl-8-isobutylbacteriochlorophyllide
d
+ H
+
+ (2
E
,6
E
)-farnesyl diphosphate → 12-ethyl-8-isobutylbacteriochlorophyll
d
+
diphosphate
2 prenyl diphosphate + terpendole J → 2
diphosphate
+ 20,21-diprenylterpendole J
L-5-hydroxyornithine + ATP → L-hOrn-AMP +
diphosphate
geranylgeranyl diphosphate → casbene +
diphosphate
2,4,6-trihydroxybenzophenone + prenyl diphosphate →
diphosphate
+ hyperxanthone E
homogentisate + H
+
+
all-trans
-nonaprenyl diphosphate → 2-methyl-6-all-trans-nonaprenyl-1,4-benzoquinol +
diphosphate
+ CO
2
coelenterazine disulfonate + ATP → adenylylcoelenterazine disulfonate +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (-)-α-isocomene
(3
1
R)-8,12-diethylbacteriochlorophyllide
d
+ H
+
+ (2
E
,6
E
)-farnesyl diphosphate → (3
1
R)-8,12-diethylbacteriochlorophyll
d
+
diphosphate
coenzyme A + phenylacetate + ATP → phenylacetyl-CoA +
diphosphate
+ AMP
12-ethyl-8-isobutylbacteriochlorophyllide
e
+ H
+
+ (2
E
,6
E
)-farnesyl diphosphate → 12-ethyl-8-isobutylbacteriochlorophyll
e
+
diphosphate
β-alanine + (R)-4-phosphopantoate + ATP → (
R
)-4'-phosphopantothenate + H
+
+
diphosphate
+ AMP
geranylgeranyl diphosphate → elisabethatriene +
diphosphate
geranyl diphosphate → (-)-sabinene +
diphosphate
(13E)-labda-7,13-dien-15-yl diphosphate → labda-7,13(16),14-triene +
diphosphate
coenzyme A + sinapate + ATP → sinapoyl-CoA +
diphosphate
+ AMP
isopentenyl diphosphate + (2
E
,6
E
)-farnesyl diphosphate → geranylgeranyl diphosphate +
diphosphate
N
-acetyl-7-
O
-acetylneuraminate + CTP →
diphosphate
+ CMP-
N
-acetyl-7-
O
-acetyl-β-neuraminate
12-ethyl-8-propylbacteriochlorophyllide
d
+ H
+
+ (2
E
,6
E
)-farnesyl diphosphate → 12-ethyl-8-propylbacteriochlorophyll
d
+
diphosphate
H
+
+ L-tryptophan + ATP → (L-tryptophanyl)adenylate +
diphosphate
2
N
-hydroxy-
N
-succinylcadaverine + ATP → pre-bisucaberin + H
+
+
diphosphate
+ AMP
prenyl diphosphate + deoxyadlupulone →
diphosphate
+ adlupulone
diaminobutyryl-citryl-ethanolamine + 2-oxoglutarate + ATP → diaminobutyryl-citryl-ethanolamino-α-ketoglutarate + H
+
+
diphosphate
+ AMP
pppGpp + H
2
O → H
+
+
diphosphate
+ GTP
isopentenyl diphosphate + all-
trans
-octaprenyl diphosphate →
all-trans
-nonaprenyl diphosphate +
diphosphate
2 geranylgeranyl diphosphate + NADPH + H
+
→ 2
diphosphate
+ lycopaoctaene + NADP
+
L-alanine + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-alanine + H
+
+
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (
E
)-2-
epi
-β-caryophyllene
2 ATP → 2
diphosphate
+ cyclic di-3',5'-adenylate
(2Z,6Z)-farnesyl diphosphate →
diphosphate
+ (-)-β-santalene
coenzyme A + ATP + benzoate → benzoyl-CoA +
diphosphate
+ AMP
H
2
O + dTTP → H
+
+
diphosphate
+ dTMP
peregrinol diphosphate → 9,13-epoxylabda-14-ene +
diphosphate
2 (2
E
,6
E
)-farnesyl diphosphate + NADPH + H
+
→ 2
diphosphate
+ C30 botryococcene + NADP
+
12-ethyl-8-propylbacteriochlorophyllide
e
+ H
+
+ (2
E
,6
E
)-farnesyl diphosphate → 12-ethyl-8-propylbacteriochlorophyll
e
+
diphosphate
5-phospho-α-D-ribose 1-diphosphate + 4-imidazoleacetate + ATP → 1-(5-phosphoribosyl)imidazole-4-acetate +
diphosphate
+ phosphate + ADP
coenzyme A +
trans
-cinnamate + ATP → (
E
)-cinnamoyl-CoA +
diphosphate
+ AMP
geranylfarnesyl diphosphate → stellata-2,6,19-triene +
diphosphate
9 isopentenyl diphosphate + (2
E
,6
E
)-farnesyl diphosphate → 9
diphosphate
+ all-
trans
-dodecaprenyl diphosphate
geranyl diphosphate → tricyclene +
diphosphate
(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate → 7,8-dihydropteroate +
diphosphate
(3
1
R)-8,12-diethylbacteriochlorophyllide
c
+ H
+
+ (2
E
,6
E
)-farnesyl diphosphate → (3
1
R)-8,12-diethylbacteriochlorophyll
c
+
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (+)-β-caryophyllene
geranyl diphosphate →
diphosphate
+ (+)-3-carene
geranyl diphosphate →
diphosphate
+ (-)-β-phellandrene
prenyl diphosphate + cyclo-acetoacetyl-
L
-tryptophan →
diphosphate
+ β-cyclopiazonate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ α-guaiene
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ β-patchoulene
H
2
O + L-methionine + ATP →
S
-adenosyl-L-methionine +
diphosphate
+ phosphate
H
2
O + geranylgeranyl diphosphate → (6E,10E)-geranyllinalool +
diphosphate
H
2
O + CTP → CMP + H
+
+
diphosphate
3 isopentenyl diphosphate + prenyl diphosphate → 3
diphosphate
+ nerylneryl diphosphate
(2
S
,5
S
)-5-carboxymethyl proline + ATP → (3
S
,5
S
)-carbapenam-3-carboxylate + H
+
+
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ α-chamigrene
N
3
-oct-2-enoyl-
N
3
-hydroxy-1,3-diaminopropane +
N
1
-citryl-
N
3
-oct-2-enoyl-
N
3
-hydroxy-1,3-diaminopropane + ATP → acinetoferrin + H
+
+
diphosphate
+ AMP
(
R
)-lipoate + H
+
+ ATP → (lipoyl)adenylate +
diphosphate
(6aR,11aR)-3,9-dihydroxypterocarpan + prenyl diphosphate →
diphosphate
+ (-)-phaseollidin
glycine + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-glycine + H
+
+
diphosphate
+ AMP
geranylgeranyl diphosphate → cycloaraneosene +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ (
S
)-β-bisabolene
(2R,3S)-2-decyl-3-hydroxytetradecanoate + ATP → 3-decyl-4-undecyloxetan-2-one +
diphosphate
+ AMP
[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl triphosphate]-D-ribitol + (
S
)-2-hydroxyglutarate → 7,8-dihydromethanopterin +
diphosphate
coenzyme A + ATP +
N
-methylanthranilate →
N
-methylanthraniloyl-CoA +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate →
diphosphate
+ γ-patchoulene
2 (2
E
,6
E
)-farnesyl diphosphate → 2
diphosphate
+ 15-
cis
-4,4'-diapophytoene
prenyl diphosphate + hapalindole G →
diphosphate
+ ambiguine A
umbelliferone + geranyl diphosphate → 8-geranylumbelliferone +
diphosphate
all-
trans
-hexaprenyl diphosphate + 4-hydroxybenzoate →
diphosphate
+ 3-hexaprenyl-4-hydroxybenzoate
all-
trans
-octaprenyl diphosphate + 4-hydroxybenzoate → 3-octaprenyl-4-hydroxybenzoate +
diphosphate
H
+
+ GTP + D-
erythro
-D-
gluco
-octose α-1-phosphate → GDP-D-
erythro
-α-D-
gluco
-octose +
diphosphate
lavandulyl diphosphate + H
2
O → lavandulol +
diphosphate
geranyl diphosphate → sabinene +
diphosphate
pentadecanoate + coenzyme A + ATP → pentadecanoyl-CoA +
diphosphate
+ AMP
orsellinate + (2
E
,6
E
)-farnesyl diphosphate → grifolate +
diphosphate
ATP + ursodeoxycholate + coenzyme A → AMP +
diphosphate
+ ursodeoxycholoyl-CoA
4-nitrobenzoate + coenzyme A + ATP → 4-nitrobenzoyl-CoA + AMP +
diphosphate
(2
E
,6
E
)-farnesyl diphosphate → sesquisabinene +
diphosphate
geranyl diphosphate + L-glutamate →
N
-geranyl-L-glutamate +
diphosphate
ATP + cob(I)alamin + H
2
O → adenosylcobalamin +
diphosphate
+ phosphate
protocatechuate + all-
trans
-hexaprenyl diphosphate → 3-
all trans
-hexaprenyl-4,5-dihydroxybenzoate +
diphosphate
vanillate + all-
trans
-hexaprenyl diphosphate →
diphosphate
+ 3-
all trans
-hexaprenyl-4-hydroxy-5-methoxybenzoate
N
6
-acetyl-
N
6
-hydroxy-L-lysine + ATP + citrate →
N
1
-citryl-
N
6
-acetyl-
N
6
-hydroxy-L-lysine + H
+
+
diphosphate
+ AMP
2 isopentenyl diphosphate + prenyl diphosphate → 2
diphosphate
+ (2Z,6Z)-farnesyl diphosphate
ammonium + ATP + nicotinate adenine dinucleotide → NAD
+
+ H
+
+
diphosphate
+ AMP
pre-sodorifen diphosphate → sodorifen +
diphosphate
CTP + (2-aminoethyl)phosphonate → CMP-(2-aminoethyl)phosphonate +
diphosphate
2-phospho-L-lactate + GTP + H
+
→ L-lactyl-2-diphospho-5'-guanosine +
diphosphate
FMN + H
+
+ ATP → FAD +
diphosphate
coenzyme A + decanoate + ATP → decanoyl-CoA +
diphosphate
+ AMP
coenzyme A + stearate + ATP → stearoyl-CoA +
diphosphate
+ AMP
coenzyme A + palmitate + ATP → palmitoyl-CoA +
diphosphate
+ AMP
ATP + L-alanine + tRNA(Ala) → AMP +
diphosphate
+ Ala-tRNA(Ala)
ATP + L-arginine + tRNA(Arg) → AMP + L-arginyl-[tRNAArg] +
diphosphate
ATP + L-arginine + tRNA(Arg), mitochondrial → AMP + L-arginyl-[tRNAArg] +
diphosphate
ATP + L-asparagine + tRNA(Asn) → AMP + Asn-tRNA(Asn) +
diphosphate
ATP + L-asparagine + tRNA(Asn), mitochondrial → AMP +
diphosphate
+ Asn-tRNA(Asn)
ATP + L-aspartate + tRNA(Asp) → AMP + Asp-tRNA(Asp) +
diphosphate
2 (2E,6E)-farnesyl diphosphate + H+ + NADPH → 2
diphosphate
+ NADP+ + squalene
ATP + L-aspartate + tRNA(Asp), mitochondrial → AMP + Asp-tRNA(Asp) +
diphosphate
isopentenyl diphosphate + octadecaprenyl diphosphate →
diphosphate
+ nonadecaprenyl diphosphate
isopentenyl diphosphate + nonadecaprenyl diphosphate →
diphosphate
+ icosaprenyl diphosphate
icosaprenyl diphosphate + isopentenyl diphosphate →
diphosphate
+ henicosaprenyl diphosphate
all-trans-hexaprenyl diphosphate + isopentenyl diphosphate →
diphosphate
+ di-trans,poly-cis-heptaprenyl diphosphate
di-trans,poly-cis-heptaprenyl diphosphate + isopentenyl diphosphate →
diphosphate
+ all-trans-octaprenyl diphosphate
isopentenyl diphosphate + all-trans-octaprenyl diphosphate →
diphosphate
+ di-trans,poly-cis-nonaprenyl diphosphate
di-trans,poly-cis-decaprenyl diphosphate + isopentenyl diphosphate →
diphosphate
+ undecaprenyl diphosphate
isopentenyl diphosphate + undecaprenyl diphosphate →
diphosphate
+ all-trans-dodecaprenyl diphosphate
isopentenyl diphosphate + all-trans-tridecaprenyl diphosphate →
diphosphate
+ tetradecaprenyl diphosphate
isopentenyl diphosphate + tetradecaprenyl diphosphate →
diphosphate
+ pentadecaprenyl diphosphate
isopentenyl diphosphate + pentadecaprenyl diphosphate →
diphosphate
+ hexadecaprenyl diphosphate
henicosaprenyl diphosphate + isopentenyl diphosphate →
diphosphate
+ docosaprenyl diphosphate
ATP + L-cysteine + tRNA(Cys) → AMP + Cys-tRNA(Cys) +
diphosphate
ATP + L-glutamine + tRNA(Gln) → AMP +
diphosphate
+ Gln-tRNA(Gln)
ATP + L-glutamate + tRNA(Glu) → AMP +
diphosphate
+ Glu-tRNA(Glu)
ATP + L-glutamate + tRNA(Glu), mitochondrial → AMP +
diphosphate
+ Glu-tRNA(Glu)
ATP + glycine + tRNA(Gly) → AMP +
diphosphate
+ Gly-tRNA(Gly)
ATP + L-isoleucine + tRNA(Ile) → AMP +
diphosphate
+ Ile-tRNA(Ile)
ATP + L-isoleucine + tRNA(Ile), mitochondrial → AMP +
diphosphate
+ Ile-tRNA(Ile)
ATP + L-methionine + tRNA(Met), mitochondrial → AMP +
diphosphate
+ Met-tRNA(Met)
ATP + L-leucine + tRNA(Leu), mitochondrial → AMP +
diphosphate
+ Leu-tRNA(Leu)
ATP + L-lysine + tRNA(Lys) → AMP +
diphosphate
+ Lys-tRNA(Lys)
ATP + L-phenylalanine + tRNA(Phe) → AMP +
diphosphate
+ Phe-tRNA(Phe)
ATP + L-phenylalanine + tRNA(Phe), mitochondrial → AMP +
diphosphate
+ Phe-tRNA(Phe)
ATP + L-proline + tRNA(Pro) → AMP +
diphosphate
+ H+ + Pro-tRNA(Pro)
ATP + L-histidine + tRNA(His) → AMP +
diphosphate
+ His-tRNA(His)
ATP + L-threonine + tRNA(Thr) → AMP +
diphosphate
+ Thr-tRNA(Thr)
ATP + L-threonine + tRNA(Thr), mitochondrial → AMP +
diphosphate
+ Thr-tRNA(Thr)
ATP + L-lysine + tRNA(Lys), mitochondrial → AMP +
diphosphate
+ Lys-tRNA(Lys)
ATP + L-histidine + tRNA(His), mitochondrial → AMP +
diphosphate
+ His-tRNA(His)
ATP + L-serine + tRNA(Ser) → AMP +
diphosphate
+ Ser-tRNA(Ser)
ATP + L-tryptophan + tRNA(Trp) → AMP +
diphosphate
+ Trp-tRNA(Trp)
ATP + L-methionine + tRNA(Met) → AMP +
diphosphate
+ Met-tRNA(Met)
ATP + L-tryptophan + tRNA(Trp), mitochondrial → AMP +
diphosphate
+ Trp-tRNA(Trp)
ATP + L-valine + tRNA(Val) → AMP +
diphosphate
+ Val-tRNA(Val)
ATP + L-tyrosine + a tRNAtyr → AMP +
diphosphate
+ Tyr-tRNA(Tyr)
ATP + L-tyrosine + tRNA(Tyr), mitochondrial → AMP +
diphosphate
+ Tyr-tRNA(Tyr)
ATP + L-valine + tRNA(Val), mitochondrial → AMP +
diphosphate
+ Val-tRNA(Val)
GTP + H2O → cyclic-GMP +
diphosphate
+ H+
2 geranylgeranyl diphosphate → 2
diphosphate
+ all-
trans
-phytoene
neryl diphosphate → nerol +
diphosphate
Reversible reaction (106)
H
+
+ sulfate + ATP ↔
diphosphate
+ adenosine 5'-phosphosulfate
1-(5-phospho-β-D-ribosyl)-ATP +
diphosphate
↔ 5-phospho-α-D-ribose 1-diphosphate + ATP
diphosphate
+ AMP ↔ 5-phospho-α-D-ribose 1-diphosphate + adenine
7 isopentenyl diphosphate + 2-
cis
,6-
trans
,10-
trans
-geranylgeranyl diphosphate ↔ 7
diphosphate
+ tri-
trans
,hepta-
cis
-undecaprenyl diphosphate
H
+
+ dTTP + α-D-galactose 1-phosphate ↔ dTDP-α-D-galactose +
diphosphate
H
+
+ CTP + α-D-glucopyranose 1-phosphate ↔
diphosphate
+ CDP-α-D-glucose
pyruvate + phosphate + ATP ↔ phospho
enol
pyruvate + H
+
+
diphosphate
+ AMP
α-D-galacturonate 1-phosphate + H
+
+ UTP ↔
diphosphate
+ UDP-α-D-galacturonate
isopentenyl diphosphate + ω, mono-
trans
, poly-
cis
-hexaprenyl diphosphate ↔
diphosphate
+ ω, mono-
trans
, poly-
cis
-heptaprenyl diphosphate
biotin + APO-[3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)] + ATP ↔ [3-methylcrotonoyl-CoA:carbon-dioxide ligase(ADP-forming)] +
diphosphate
+ AMP
acetate +
diphosphate
↔ acetyl phosphate + phosphate
β-L-arabinose 1-phosphate + H
+
+ UTP ↔
diphosphate
+ UDP-β-L-arabinopyranose
isopentenyl diphosphate + all-
trans
-undecaprenyl diphosphate ↔ all-
trans
-dodecaprenyl diphosphate +
diphosphate
a 2,4-dioxotetrahydropyrimidine D-ribonucleotide +
diphosphate
↔ 5-phospho-α-D-ribose 1-diphosphate + 5,6-dihydrouracil
CTP ↔ cyclic 3',5'-cytidine monophosphate +
diphosphate
isopentenyl diphosphate + prenyl diphosphate ↔
diphosphate
+ geranyl diphosphate
2 prenyl diphosphate + aspulvinone-e ↔ 2
diphosphate
+ aspulvinone-h
L-citrulline + L-aspartate + ATP ↔ L-arginino-succinate + H
+
+
diphosphate
+ AMP
4,6,8-trihydroxydibenzodiazepinone + (2
E
,6
E
)-farnesyl diphosphate ↔ diazepinomicin +
diphosphate
orotidine 5'-phosphate +
diphosphate
↔ 5-phospho-α-D-ribose 1-diphosphate + orotate
9 isopentenyl diphosphate + (2
Z
,6
E
)-farnesyl diphosphate ↔ 9
diphosphate
+ ω, mono-
trans
,deca-
cis
-dodecaprenyl diphosphate
β-D-fructofuranose 6-phosphate +
diphosphate
↔ β-D-fructose 1,6-bisphosphate + H
+
+ phosphate
H
+
+ MoO
2
-molybdopterin cofactor + GTP ↔ guanylyl molybdenum cofactor +
diphosphate
2 isopentenyl diphosphate + geranylgeranyl diphosphate ↔ 2
diphosphate
+ all-
trans
-hexaprenyl diphosphate
isopentenyl diphosphate + di-
trans
,poly-
cis
-heptaprenyl diphosphate ↔ di-
trans
,poly-
cis
-octaprenyl diphosphate + H
+
+
diphosphate
prenyl diphosphate + 5,10-dihydrophenazine-1-carboxylate ↔ 5,10-dihydro-9-dimethylallylphenazine 1-carboxylate +
diphosphate
2 GTP + H
+
↔ P
1
,P
4
-
bis
(5'-guanosyl) tetraphosphate +
diphosphate
5-phospho-α-D-ribose 1-diphosphate + nicotinate + H
2
O + ATP ↔ β-nicotinate D-ribonucleotide +
diphosphate
+ phosphate + ADP
prenyl diphosphate + L-tyrosine ↔ 4-
O
-dimethylallyl-L-tyrosine +
diphosphate
α-D-xylose 1-phosphate + H
+
+ UTP ↔
diphosphate
+ UDP-α-D-xylose
diphosphate
+ GMP ↔ 5-phospho-α-D-ribose 1-diphosphate + guanine
isopentenyl diphosphate + (2
Z
,6
Z
,10
E
)-tetraprenyl diphosphate ↔
diphosphate
+ ω, mono-
trans
, poly-
cis
-pentaprenyl diphosphate
isopentenyl diphosphate + neryl diphosphate ↔
diphosphate
+ (2Z,6Z)-farnesyl diphosphate
phytyl diphosphate + H
+
+ chlorophyllide
a
↔ chlorophyll
a
+
diphosphate
H
2
O + (2
E
,6
E
)-farnesyl diphosphate ↔
diphosphate
+ (-)-α-bisabolol
2-
O
,3-dimethylflaviolin + geranyl diphosphate ↔
diphosphate
+ 6-linalyl-2-O,3-dimethylflaviolin
coenzyme A + ATP + C27-mycolipanoate ↔ C27-mycolipanoyl-CoA +
diphosphate
+ AMP
β-nicotinate D-ribonucleotide +
diphosphate
↔ 5-phospho-α-D-ribose 1-diphosphate + nicotinate + H
+
L-threonine + hydrogencarbonate + ATP ↔ H
2
O + (L-threonylcarbamoyl)adenylate +
diphosphate
GTP ↔
diphosphate
+ cyclic-GMP
N
-acetyl-α-D-glucosamine 1-phosphate + H
+
+ UTP ↔
diphosphate
+ UDP-
N
-acetyl-α-D-glucosamine
diphosphate
+ oxaloacetate ↔ phospho
enol
pyruvate + phosphate + CO
2
mycosporine glycine + L-serine + ATP ↔ 2 H
+
+ shinorine +
diphosphate
+ AMP
prephytoene diphosphate ↔ all-
trans
-phytoene +
diphosphate
GTP + ATP ↔ 2
diphosphate
+ cyclic Gp(2'-5')Ap(3'-5')
olivetolate + neryl diphosphate ↔
diphosphate
+ cannabinerolate
2 prenyl diphosphate ↔ lavandulyl diphosphate +
diphosphate
isopentenyl diphosphate + 2-
cis
,6-
trans
,10-
trans
-geranylgeranyl diphosphate ↔ di-
trans
,di-
cis
-pentaprenyl diphosphate + H
+
+
diphosphate
isopentenyl diphosphate + di-
trans
,poly-
cis
-hexaprenyl diphosphate ↔ di-
trans
,poly-
cis
-heptaprenyl diphosphate + H
+
+
diphosphate
β-nicotinate D-ribonucleotide + H
+
+ ATP ↔
diphosphate
+ nicotinate adenine dinucleotide
N
-(5-phosphoribosyl)-anthranilate +
diphosphate
↔ anthranilate + 5-phospho-α-D-ribose 1-diphosphate
H
+
+ dTTP + α-D-glucopyranose 1-phosphate ↔ dTDP-α-D-glucose +
diphosphate
1,4-dihydroxy-2-naphthoate + H
+
+ all-
trans
-heptaprenyl diphosphate ↔ demethylmenaquinol-7 +
diphosphate
+ CO
2
α-D-glucuronate 1-phosphate + H
+
+ UTP ↔
diphosphate
+ UDP-α-D-glucuronate
prenyl diphosphate + L-tryptophan ↔ 7-(3-methylbut-2-enyl)-L-tryptophan +
diphosphate
isopentenyl diphosphate + di-
trans
,di-
cis
-pentaprenyl diphosphate ↔ di-
trans
,poly-
cis
-hexaprenyl diphosphate + H
+
+
diphosphate
(2
E
,6
E
)-farnesyl diphosphate ↔
diphosphate
+ (+)-
epi
-β-santalene
L-ascorbate +
diphosphate
↔ 2-phospho-L-ascorbate + H
+
+ phosphate
H
+
+ L-aspartate + ATP ↔ (L-aspartyl)adenylate +
diphosphate
H
+
+ flaviolin + geranyl diphosphate ↔
diphosphate
+ 3-linalylflaviolin
isopentenyl diphosphate + all-
trans
-dodecaprenyl diphosphate ↔ all-
trans
-tridecaprenyl diphosphate +
diphosphate
NADP
+
+ squalene +
diphosphate
↔ NADPH + presqualene diphosphate + H
+
isopentenyl diphosphate + ω, mono-
trans
, poly-
cis
-pentaprenyl diphosphate ↔
diphosphate
+ ω, mono-
trans
, poly-
cis
-hexaprenyl diphosphate
2-
O
,3-dimethylflaviolin + geranyl diphosphate ↔
diphosphate
+ 7-O-geranyl-2-O,3-dimethylflaviolin
β-nicotinamide D-ribonucleotide + H
+
+ ATP ↔ NAD
+
+
diphosphate
2 H
+
+ geranylgeranyl diphosphate + chlorophyllide
b
↔
diphosphate
+ geranylgeranyl chlorophyll b
H
2
O + L-phenylalanine + ATP ↔ H
+
+
diphosphate
+ AMP + D-phenylalanine
phospho
enol
pyruvate + H
+
+ phosphate ↔ pyruvate +
diphosphate
coenzyme A + acetate + ATP ↔ acetyl-CoA +
diphosphate
+ AMP
5-phospho-β-D-ribosylamine + L-glutamate +
diphosphate
↔ 5-phospho-α-D-ribose 1-diphosphate + H
2
O + L-glutamine
isopentenyl diphosphate + geranyl diphosphate ↔
diphosphate
+ (2
E
,6
E
)-farnesyl diphosphate
coenzyme A + 2,4-dichlorobenzoate + ATP ↔ 2,4-dichlorobenzoyl-CoA +
diphosphate
+ AMP
(2
E
,6
E
)-farnesyl diphosphate ↔
diphosphate
+ (+)-β-muurolene
isopentenyl diphosphate + di-
trans
,poly-
cis
-nonaprenyl diphosphate ↔ di-
trans
,poly-
cis
-decaprenyl diphosphate + H
+
+
diphosphate
(-)-
ent
-copalyl diphosphate + H
2
O ↔ (-)-
ent
-copalol +
diphosphate
molybdopterin + GTP ↔ guanylyl molybdenum cofactor +
diphosphate
streptomycin + ATP ↔ 3''-adenylylstreptomycin +
diphosphate
2 isopentenyl diphosphate + 3 prenyl diphosphate ↔ 4
diphosphate
+ geranylfarnesyl diphosphate
H
2
O + malonyl-CoA + ATP + ononin ↔ 2 H
+
+ coenzyme A + formononetin-7-
O
-glucoside-6''-malonate +
diphosphate
+ AMP
glycerol +
diphosphate
↔ H
+
+ phosphate +
sn
-glycerol 3-phosphate
isopentenyl diphosphate + di-
trans
,poly-
cis
-octaprenyl diphosphate ↔ di-
trans
,poly-
cis
-nonaprenyl diphosphate + H
+
+
diphosphate
H
+
+ UTP + α-D-galactose 1-phosphate ↔
diphosphate
+ UDP-α-D-galactose
isopentenyl diphosphate +
all-trans
-nonaprenyl diphosphate ↔ all-
trans
-decaprenyl diphosphate +
diphosphate
uridine + H
+
+ L-cysteine + ATP ↔ L-alanine + 2-thiouridine +
diphosphate
+ AMP
β-nicotinate D-ribonucleotide +
diphosphate
+ CO
2
↔ 2 H
+
+ 5-phospho-α-D-ribose 1-diphosphate + quinolinate
isopentenyl diphosphate + ω, mono-
trans
, poly-
cis
-heptaprenyl diphosphate ↔
diphosphate
+ ω, mono-
trans
, poly-
cis
-octaprenyl diphosphate
H
+
+ L-serine + ATP ↔ (L-seryl)adenylate +
diphosphate
(+)-copalyl diphosphate + H
2
O ↔ (+)-copalol +
diphosphate
2 2-
cis
,6-
trans
,10-
trans
-geranylgeranyl diphosphate ↔ 2
diphosphate
+ 15-
cis
-phytoene
chlorophyllide
a
2
+ phytyl diphosphate + H
+
↔ chlorophyll
a
2
+
diphosphate
H+ + CTP + phosphatidate ↔
diphosphate
+ a CDP-diacylglycerol
CTP + H+ + phosphatidate ↔
diphosphate
+ a CDP-diacylglycerol
4-hydroxybenzoate + di-trans,poly-cis-nonaprenyl diphosphate ↔
diphosphate
+ 2 H+ + 3-nonaprenyl-4-hydroxybenzoate
hexadecaprenyl diphosphate + isopentenyl diphosphate ↔
diphosphate
+ heptadecaprenyl diphosphate
heptadecaprenyl diphosphate + isopentenyl diphosphate ↔
diphosphate
+ octadecaprenyl diphosphate
ATP + coenzyme A + myristate ↔ AMP + myristoyl-CoA +
diphosphate
ATP + coenzyme A + tetracosanoic acid ↔ AMP +
diphosphate
+ lignoceroyl-CoA
coenzyme A + ATP + behenate ↔ docosanoyl-CoA + AMP +
diphosphate
coenzyme A + ATP + tetracosanoic acid ↔ lignoceroyl-CoA + AMP +
diphosphate
coenzyme A + ATP + cerotic acid ↔ cerotoyl-CoA + AMP +
diphosphate
coenzyme A + ATP + behenate ↔
diphosphate
+ AMP + docosanoyl-CoA
coenzyme A + ATP + tetracosanoic acid ↔
diphosphate
+ AMP + lignoceroyl-CoA
ATP + coenzyme A + behenate ↔ AMP +
diphosphate
+ docosanoyl-CoA
ATP + coenzyme A + cerotic acid ↔ AMP +
diphosphate
+ cerotoyl-CoA
coenzyme A + ATP + myristate ↔ myristoyl-CoA + AMP +
diphosphate
ATP + coenzyme A + arachidate ↔ AMP +
diphosphate
+ icosanoyl-CoA