an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

2-C-methyl-D-erythritol 4-phosphate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

CO₂

thiamine diphosphate

2-(α-hydroxyethyl)thiamine diphosphate

H₂O

N-succinyl-L,L-2,6-diaminopimelate

5-phospho-β-D-ribosylamine

4'-phosphopantetheine

(R)-4'-phosphopantothenoyl-L-cysteine

N-succinyl-2-amino-6-ketopimelate

(S)-2,3,4,5-tetrahydrodipicolinate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

(R)-2,3-dihydroxy-3-methylpentanoate

coproporphyrinogen III

quinolinate

β-nicotinate D-ribonucleotide

carbamoyl phosphate

5-aminolevulinate

glycerone phosphate

S-acetyldihydrolipoamide

dihydrolipoamide

citrate

oxaloacetate

dethiobiotin

7,8-diaminopelargonate

(R)-pantothenate

arsenite

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

(S)-dihydroorotate

5-methylcytosine

isopentenyl diphosphate

preuroporphyrinogen

hydrogen peroxide

N-acetylglutamyl-phosphate

prenyl diphosphate

3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA

3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-hydroxypropanoyl-CoA

porphobilinogen

pseudouridine 5'-phosphate

phosphoenolpyruvate

3-demethylubiquinol-6

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

8-amino-7-oxononanoate

thiamine phosphate

5-amino-6-(D-ribitylamino)uracil

orotidine 5'-phosphate

nicotinate adenine dinucleotide

4-hydroxy-2-nonenal

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

N-acetyl-L-glutamate 5-semialdehyde

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

L-selenocystathionine

pimeloyl-CoA

2-dehydropantoate

3-methyl-2-oxobutanoate

acetyl phosphate

5-amino-6-(5-phospho-D-ribosylamino)uracil

DNA without lesion

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

3-amino-1-hydroxyacetone 1-phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

(R)-4'-phosphopantothenate

2-iminoacetate

carbon monoxide

4-amino-2-methyl-5-pyrimidinemethanol

(3R)-3-hydroxy-2-oxo-4 phosphooxybutanoate

4-phosphooxy-L-threonine

(2S)-2-amino-3-oxo-4-phosphooxybutanoate

1,4-dihydroxy-2-naphthoate

1-deoxy-L-glycero-tetrulose 4-phosphate

5-amino-6-(5-phospho-D-ribitylamino)uracil

oxalosuccinate

α-D-glucosamine 1-phosphate

N⁵-carboxyaminoimidazole ribonucleotide

3-dehydroquinate

3-dehydroshikimate

shikimate

L-arginino-succinate

2-amino-3-carboxymuconate-6-semialdehyde

(S)-4-amino-5-oxopentanoate

pseudouridine

(1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1 (10),2-dien-4-oate

(S)-4-hydroxy-2-oxohexanoate

(2Z,4Z)-2-hydroxyhexa-2,4-dienoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

5-hydroxy-3-[(3aS,4S,5R,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

(2E)-3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]prop-2-enoyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-indene-4-carboxylate

H₂

ammonia

enol-phenylpyruvate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(2E,6E)-farnesyl diphosphate

2-octaprenylphenol

5,10-methenyltetrahydrofolate mono-L-glutamate

1-oleoyl-2-lyso-glycerone phosphate

(2R)-2,3-dihydroxy-3-methylbutanoate

3-phospho-D-glyceroyl-phosphate

2,3-diphospho-D-glycerate

3-phospho-D-glycerate

2-phospho-D-glycerate

sn-glycerol 1-phosphate

sn-glycerol 3-phosphate

oxygen

coproporphyrinogen I

uroporphyrinogen-I

uroporphyrinogen-III

protoporphyrin IX

protoporphyrinogen IX

protoheme

DNA with lesion

(glutathion-S-yl)-4-hydroxy-2-nonenal

γ-L-glutamyl-L-cysteine

D-alanyl-D-alanine

2-iminopropanoate

2-iminosuccinate

L-homocysteine

4-methylphenol

L-α-amino-ε-keto-pimelate

L-arginine

L-lysine

L-glutamate

D-glutamate

L-glutamine

glycine

L-serine

L-alanine

L-leucine

β-alanine

L-valine

L-phenylalanine

L-methionine

L-cysteine

L,L-diaminopimelate

L-aspartyl-4-phosphate

L-ornithine

L-tyrosine

L-aspartate

L-cystathionine

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

L-citrulline

S-adenosyl-L-methionine

L-aspartate 4-semialdehyde

S-adenosyl-L-homocysteine

L-glutamate-5-semialdehyde

L-homoserine

L-4-hydroxyglutamate semialdehyde

meso-diaminopimelate

seleno-L-homocysteine

N-acetyl-L-glutamate

D-alanine

ADP

ATP

GTP

AMP

GMP

XMP

dATP

dADP

dGTP

dGDP

GDP

ITP

IDP

dITP

dIDP

5'-deoxyadenosine

adenylo-succinate

IMP

2'-deoxyguanosine

2'-deoxyadenosine

dGMP

dAMP

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramate

UDP-α-D-glucose

UDP-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

uracil

cytosine

thymine

preQ₁

NAD⁺

NADP⁺

NADH

NADPH

dCMP

dUMP

dTMP

dCDP

dTDP

dUDP

dCTP

dTTP

dUTP

CDP

UDP

β-nicotinamide D-ribonucleotide

CTP

UTP

CMP

UMP

5-fluorouracil

5-fluorocytosine

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

5-phospho-α-D-ribose 1-diphosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

4-phospho-D-erythronate

α-D-glucopyranose 1-phosphate

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

sucrose 6^F-phosphate

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

a peptidoglycan dimer (S. aureus)

a peptidoglycan dimer (E. faeciums)

decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide)

a peptidoglycan dimer (mycobacteria)

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)

a peptidoglycan dimer (meso-diaminopimelate containing)

a peptidoglycan with L,D cross-links (mycobacteria)

a peptidoglycan with D,D cross-links (mycobacteria)

a peptidoglycan with D,D cross-link (S. aureus)

a peptidoglycan tetramer with a D,D cross-link (Enterococcus faecium)

β-D-fructofuranose

glycolaldehyde

D-glyceraldehyde

sucrose

trans,octacis-decaprenyl phosphate

mono-trans,octa-cis-decaprenyl diphosphate

geranyl diphosphate

di-trans,octa-cis-undecaprenyl phosphate

di-trans,octa-cis-undecaprenyl diphosphate

all-trans-octaprenyl diphosphate

all-trans-decaprenyl diphosphate

all-trans-heptaprenyl diphosphate

all-trans-hexaprenyl diphosphate

all-trans-nonaprenyl diphosphate

3-octaprenyl-4-hydroxybenzoate

3-decaprenyl-4-hydroxybenzoate

3-heptaprenyl-4-hydroxybenzoate

3-hexaprenyl-4-hydroxybenzoate

3-nonaprenyl-4-hydroxybenzoate

1-oleoyl-2-palmitoyl-phosphatidylglycerol

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

dioleoyl phosphatidate

1-oleoyl-sn-glycerol 3-phosphate

1-C16:0-α,ω-dicarboxyl-2-lysophosphatidate

protocatechuate

ethanol

1-propanal

acetaldehyde

menadione

diacetyl

pyruvate

2-oxoglutarate

glyoxylate

3-phenyl-2-oxopropanoate

4-aminobenzoate

acetate

(R)-pantoate

orotate

(S)-1-pyrroline-5-carboxylate

3-oxoadipate

formate

(R)-lactate

cis-aconitate

3-carboxy-cis,cis-muconate

D-threo-isocitrate

chorismate

succinate

fumarate

(S)-malate

4-hydroxybenzoate

menadiol

6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol

3-demethylubiquinol-9

3-demethylubiquinol-8

3-demethylubiquinol-7

3-demethylubiquinol-10

demethylmenaquinol-7

demethylmenaquinol-6

demethylmenaquinol-8

menaquinol-7

menaquinol-6

menaquinol-8

ubiquinol-9

ubiquinol-8

ubiquinol-6

ubiquinol-7

ubiquinol-10

preQ₀

(7,8-dihydropterin-6-yl)methyl diphosphate

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydroneopterin

7,8-dihydromonapterin

7,8-dihydroneopterin 3'-phosphate

7,8-dihydropteroate

7,8-dihydrofolate monoglutamate

5,6,7,8-tetrahydrofolate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

FMN

riboflavin

FAD

FMNH₂

6,7-dimethyl-8-(1-D-ribityl)lumazine

thiamine

nicotinate

nicotinamide

pyridoxal 5'-phosphate

pyridoxamine 5'-phosphate

pyridoxine 5'-phosphate

pyridoxine

pyridoxal

pyridoxamine

coenzyme A

(R)-NADHX

(S)-NADHX

glycine betaine

succinyl-CoA

acetyl-CoA

malonyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxooctanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxohexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxobutanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA

(3S)-hydroxyadipyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

3'-dephospho-CoA

oleoyl-CoA

3-oxoadipyl-CoA

3-oxodecanoyl-CoA

3-oxohexanoyl-CoA

3-oxooctanoyl-CoA

acetoacetyl-CoA

hexadecanedioyl-CoA

propanoyl-CoA

cerotoyl-CoA

2-carboxy-cerotoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(S)-3-hydroxydecanoyl-CoA

(S)-3-hydroxyhexanoyl-CoA

(S)-3-hydroxyoctanoyl-CoA

(S)-methylmalonyl-CoA

3,24-dioxocholest-4-en-26-oyl-CoA

24-hydroxy-3-oxocholest-4-en-26-oyl-CoA

androsta-1,4-diene-3,17-dione

androst-4-ene-3,17-dione

9α-hydroxyandrosta-1,4-diene-3,17-dione

3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione

3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

spermidine

putrescine

2-aminoprop-2-enoate

trimethyl sulfonium

hydrogencarbonate

superoxide

phosphate

diphosphate

chloride

Zn²⁺

Fe²⁺

H⁺

ammonium

dimethyl sulfide

glutathione

3-sulfopyruvate

L-cysteate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2,4-dinitrophenyl-S-glutathione

1-chloro-2,4-dinitrobenzene