an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

S-ribosyl-L-homocysteine

autoinducer 2

enolaldehyde

5,6-dimethylbenzimidazole

dialurate

(R)-mevalonate diphosphate

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

enol-phenylpyruvate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

ammonia

2-(α-hydroxyethyl)thiamine diphosphate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

5-amino-6-(5-phospho-D-ribitylamino)uracil

acetyl phosphate

L-β-lysine

4-pyridoxolactone

(3R)-3-hydroxy-2-oxo-4 phosphooxybutanoate

4-phosphooxy-L-threonine

orotidine 5'-phosphate

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

hydrogen peroxide

oxalosuccinate

S-methyl-5-thio-α-D-ribose 1-phosphate

5-deoxy-α-ribose 1-phosphate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

carbonic acid

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

prenyl diphosphate

(R)-5-phosphomevalonate

hydrogenobyrinate

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

porphobilinogen

preuroporphyrinogen

α-ribazole

α-ribazole 5'-phosphate

N-(5-phosphoribosyl)-anthranilate

cyclohex-1,5-diene-1-carbonyl-CoA

2-oxopent-4-enoate

(S)-4-hydroxy-2-oxopentanoate

(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate

(4S)-4-hydroxy-2-oxoheptanedioate

3-phosphooxypyruvate

4-amino-2-methyl-5-pyrimidinemethanol

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

phosphoenolpyruvate

5-enolpyruvoyl-shikimate 3-phosphate

itaconate

(R)-1-aminopropan-2-ol

prephenate

3-dehydroquinate

2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate

(4-hydroxyphenyl)acetate

L-arginino-succinate

canavaninosuccinate

L-canavanine

anthranilate

hexulose 6-phosphate

(2S)-2-isopropyl-3-oxosuccinate

3-ethylmalate

2-oxovalerate

2-dehydropantoate

3-dehydroshikimate

butanoyl phosphate

2-phosphoglycolate

glycolate

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

1,4-dihydroxy-2-naphthoyl-CoA

(2S)-lactyl-2-diphospho-5'-guanosine

isopentenyl diphosphate

β-nicotinate D-ribonucleotide

D-erythro-imidazole-glycerol-phosphate

glycerone phosphate

thiamine phosphate

thiamine diphosphate

urea

S-adenosyl 3-(methylsulfanyl)propylamine

S-methyl-5'-thioadenosine

histidinal

histidinol

(R)-pantothenate

(R)-2,3-dihydroxy-3-methylpentanoate

3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA

benzoylsuccinyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-hydroxypropanoyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA

4-guanidinobutyramide

(S)-3-methyl-2-oxopentanoate

4-methyl-2-oxopentanoate

3-methyl-2-oxobutanoate

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

(S)-2,3,4,5-tetrahydrodipicolinate

citrate

α-D-ribose 1,5-bisphosphate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

coenzyme B

methanophenazine

CoB-CoM heterodisulfide

dihydromethanophenazine

(2S)-2-isopropylmalate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

3'-phosphoadenylyl-sulfate

α-D-glucosamine 1-phosphate

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

carbamoyl phosphate

O-ureido-L-homoserine

nicotinate adenine dinucleotide

shikimate

shikimate 3-phosphate

carbon monoxide

(5S)-5-benzyl-hydantoin

(5R)-5-benzyl-hydantoin

acetoacetate

oxaloacetate

1-deoxy-L-glycero-tetrulose 4-phosphate

(R)-mevalonate

(E)-2-benzylidenesuccinyl-CoA

2-carboxymethyl-3-hydroxyphenylpropanoyl-CoA

3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA

(E)-4-coumaroyl-CoA

2,3-didehydroadipyl-CoA

adenosine 5'-phosphosulfate

adenosine 5'-phosphoselenate

5-amino-6-(D-ribitylamino)uracil

7,8-didemethyl-8-hydroxy-5-deazariboflavin

oxalate

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

N⁵-carboxyaminoimidazole ribonucleotide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

4,8,12-trimethyltridecanoyl-CoA

3-oxopristanoyl-CoA

imidazole acetol-phosphate

L-histidinol phosphate

(S)-dihydroorotate

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

H₂

(R)-1-amino-2-propanol O-2-phosphate

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

CO₂

H₂O

dimethyl sulfide

5-(2-hydroxyethyl)-4-methylthiazole

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

4-methyl-5-(2-phosphooxyethyl)thiazole

coenzyme M

L-cysteate

3-sulfopyruvate

sulfate

molybdate

trithionate

OH^-

hydrogensulfite

hydrogencarbonate

sulfite

selenate

nitrite

nitrate

phosphate

triphosphate

diphosphate

Co²⁺

Mg²⁺

H⁺

ammonium

trimethyl sulfonium

agmatine

putrescine

dehydrospermidine

spermidine

tyramine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

sn-glycero-3-phosphoethanolamine

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

24-hydroxy-3-oxocholest-4-en-26-oyl-CoA

3,24-dioxocholest-4-en-26-oyl-CoA

phenylacetate

2-methylbutanoyl-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

anthraniloyl-CoA

benzoyl-CoA

(R)-2-hydroxyglutaryl-CoA

(E)-glutaconyl-CoA

itaconyl-CoA

phenylacetyl-CoA

2-methylacetoacetyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxooctanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxohexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxobutanoyl)-CoA

6-cis, 3-oxo-tridecenoyl-CoA

6-trans-3-oxo-tridecenoyl-CoA

4-trans-3-oxo-undecenoyl-CoA

(3R)-hydroxy- 5-cis, 7-trans-tetradecadienoyl-CoA

5-cis, 7-trans-3-oxo-tetradecadienoyl-CoA

(3R)-hydroxy-5-trans-dodecenoyl-CoA

(5E)-3-oxo-dodec-5-enoyl-CoA

3'-dephospho-CoA

acetyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

methylacrylyl-CoA

(2E,5Z)-tetradecenoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA

(3S)-hydroxyadipyl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

3-hydroxyisovaleryl-CoA

(E)-2-methylcrotonoyl-CoA

2-trans,6-cis-tridecadienoyl-CoA

(3R)-hydroxy, 6-cis-tridecenoyl-CoA

(3E)-undec-2-enoyl-CoA

(3R)-hydroxy-undecanoyl-CoA

2-trans-6-trans-tridecadienoyl-CoA

(3R)-hydroxy, 6-trans-tridecenoyl-CoA

2-trans, 4-trans-undecadienoyl-CoA

(3R)-hydroxy, 4-trans-undecenoyl-CoA

2-trans-nonenoyl-CoA

(3R)-hydroxy-nonanoyl-CoA

succinyl-CoA

(S)-methylmalonyl-CoA

(R)-methylmalonyl-CoA

crotonyl-CoA

(2E)-dec-2-enoyl-CoA

(2E)-oct-2-enoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(S)-3-hydroxyhexanoyl-CoA

(S)-3-hydroxydecanoyl-CoA

(S)-3-hydroxyoctanoyl-CoA

(S)-3-hydroxyhexadecanoyl-CoA

(S)-3-hydroxy-(5Z)-tetradecenoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

butanoyl-CoA

propanoyl-CoA

decanoyl-CoA

octanoyl-CoA

3-oxoadipyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

3-oxodecanoyl-CoA

3-oxohexanoyl-CoA

3-oxooctanoyl-CoA

3-oxo-(5Z)-tetradecenoyl-CoA

3-oxo-palmitoyl-CoA

(S)-3-hydroxy-isobutanoyl-CoA

FMNH₂

FAD

FADH₂

FMN

(S)-NADHX

(R)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

5,10-methenyl-tetrahydrosarcinapterin

methyl-CoM

5-formyl-tetrahydrosarcinapterin

tetrahydrosarcinapterin

5-methyl-tetrahydrosarcinapterin

molybdopterin

coenzyme A

oxidized coenzyme F₄₂₀-0

MoO₂-molybdopterin cofactor

guanylyl molybdenum cofactor

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

5-formyl-tetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

nicotinate

riboflavin

pyridoxal

(S)-1-pyrroline-5-carboxylate

adenine

2'-deoxyadenosine

2'-deoxyguanosine

adenosine

dAMP

dGMP

dATP

dGTP

dITP

dADP

dGDP

dIDP

GDP

IDP

ADP

IMP

GMP

AMP

ITP

ATP

GTP

dTMP

dCMP

dUMP

orotate

cytosine

uracil

dTDP

dTTP

CDP

CTP

dCDP

dCTP

dUDP

dUTP

UDP

UTP

UMP

CMP

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-sulfoquinovopyranose

UDP-α-D-glucose

UDP-α-D-galactose

UDP-N-acetyl-α-D-glucosamine

cob(I)alamin

adenosylcobalamin

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-5B

cobalt-precorrin-6A

cobalt-precorrin-4

cobalt-precorrin-5A

precorrin-8x

precorrin-3B

precorrin-4

precorrin-5

precorrin-1

precorrin-2

cobalt-precorrin-2

cobalt-precorrin-3

sirohydrochlorin

cobyrinate

6,7-dimethyl-8-(1-D-ribityl)lumazine

7,8-dihydroneopterin 2'-phosphate

7,8-dihydroneopterin

7,8-dihydroneopterin 3'-phosphate

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydroneopterin 2',3'-cyclic phosphate

molybdopterin adenine dinucleotide

cyclic pyranopterin phosphate

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

7,8-dihydropteroate

3-hexaprenyl-4-hydroxybenzoate

4-hydroxybenzoate

4-methylphenol

4-aminobenzoate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

butanoate

decanoate

octanoate

oleate

(R)-pantoate

acetate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

2-oxobutanoate

4-(methylsulfanyl)-2-oxobutanoate

pyruvate

2-oxoglutarate

L-α-amino-ε-keto-pimelate

L-cysteine

L-tyrosine

L-serine

glycine

L-glutamine

L-histidine

L-arginine

L-lysine

L-aspartate

L-glutamate

L-tryptophan

L-phenylalanine

D-aspartate

L-aspartyl-4-phosphate

N-acetyl-L-ornithine

N-acetyl-L-citrulline

N-acetyl-L-methionine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

L-threonine 3-O-phosphate

3-phospho-L-serine

L-citrulline

L-glutamate-5-semialdehyde

L-homoserine

L-aspartate 4-semialdehyde

L-homocysteine

L-ornithine

L-canaline

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

meso-diaminopimelate

L-methionine

L-proline

L-alanine

L-isoleucine

L-leucine

L-valine

L,L-diaminopimelate

β-alanine

chorismate

succinate

fumarate

(S)-malate

cis-aconitate

D-threo-isocitrate

(S)-lactate

propanoate

formate

methylglyoxal

diacetyl

acetone

glycolaldehyde

hydroxypyruvaldehyde phosphate

formaldehyde

acetaldehyde

(S)-lactaldehyde

(3R)-linalool

(3S)-linalool

D-myo-inositol (1,4,5)-trisphosphate

D-myo-inositol (1,3,4)-trisphosphate

D-myo-inositol (1,3,4,5)-tetrakisphosphate

D-myo-inositol (1,4)-bisphosphate

1-(oleoyl)-sn-glycero-3-phosphoethanolamine

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

geranyl diphosphate

(2E,6E)-farnesyl diphosphate

phytyl diphosphate

3-nonaprenyl-4-hydroxybenzoate

3-heptaprenyl-4-hydroxybenzoate

3-decaprenyl-4-hydroxybenzoate

3-octaprenyl-4-hydroxybenzoate

geranylgeranyl diphosphate

all-trans-nonaprenyl diphosphate

all-trans-octaprenyl diphosphate

all-trans-hexaprenyl diphosphate

all-trans-heptaprenyl diphosphate

all-trans-decaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

sucrose

N-acetyl-α-D-glucosamine 1-phosphate

N-acetyl-α-D-mannosamine

β-D-fructofuranose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

6-deoxy-5-ketofructose 1-phosphate

β-D-fructofuranose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

D-ribulose 5-phosphate

α-D-galactose 1-phosphate

β-D-glucopyranose 1-phosphate

α-D-mannose 1-phosphate

D-ribulose-1,5-bisphosphate

GDP-α-D-mannose

GDP-4-dehydro-α-D-rhamnose

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-AMP

cyclic-AMP

1-(5-phospho-β-D-ribosyl)-ATP

5'-deoxyadenosine

β-nicotinamide D-ribonucleotide

Mg-protoporphyrin

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

adenosyl-cobinamide phosphate

cob(I)yrinate a,c-diamide

cob(I)inamide

adenosylcobinamide

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

cobalt-sirohydrochlorin

cobalt-factor III

protoheme

uroporphyrinogen-I

protoporphyrinogen IX

protoporphyrin IX

uroporphyrinogen-III

S⁰

oxygen

hydrogen sulfide

sn-glycerol 1-phosphate

sn-glycerol 3-phosphate

2,3-diphospho-D-glycerate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(R)-citramalate

5,10-methenyltetrahydrofolate mono-L-glutamate

2-octaprenylphenol