an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

xanthine

2-amino-3-carboxymuconate-6-semialdehyde

aminoacetone

1-piperideine 6-carboxylate

4-oxoglutaramate

ammonia

H₂O

lipid IV_A

lipid A disaccharide (E. coli)

phosphoenolpyruvate

CO₂

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

3-deoxy-α-D-manno-2-octulosonate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

N¹-(5-phospho-β-D-ribosyl)glycinamide

5-phospho-β-D-ribosylamine

4'-phosphopantetheine

citrate

oxaloacetate

urea

thiamine diphosphate

thiamine phosphate

(S)-dihydroorotate

lipid X

urocanate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

(L-threonylcarbamoyl)adenylate

prenyl diphosphate

isopentenyl diphosphate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

3-dehydroquinate

3-deoxy-D-arabino-heptulosonate 7-phosphate

hydrogen peroxide

lipoamide

dihydrolipoamide

N-succinyl-2-amino-6-ketopimelate

(S)-2,3,4,5-tetrahydrodipicolinate

dihydroxyacetone

nicotinate adenine dinucleotide

DNA without lesion

carbamoyl phosphate

1,4-dihydroxy-2-naphthoyl-CoA

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

arsenite

coproporphyrinogen III

2-(α-hydroxyethyl)thiamine diphosphate

2-succinylbenzoate

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate

3-dehydroshikimate

shikimate

5-aminolevulinate

(S)-4-amino-5-oxopentanoate

4-methyl-2-oxopentanoate

3-methyl-2-oxobutanoate

(S)-3-methyl-2-oxopentanoate

(S)-2-amino-6-oxohexanoate

orotidine 5'-phosphate

4-imidazolone-5-propanoate

1,4-dihydroxy-2-naphthoate

4-phosphooxy-L-threonine

(3R)-3-hydroxy-2-oxo-4 phosphooxybutanoate

3-phosphooxypyruvate

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

glycerone phosphate

(2-hydroxyphenyl)acetate

homogentisate

acetoacetate

4-fumaryl-acetoacetate

1-deoxy-L-glycero-tetrulose 4-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

O-acetyl-L-serine

hydrogen selenide

acetyl phosphate

(R)-mevalonate diphosphate

3-amino-1-hydroxyacetone 1-phosphate

4-aminobutanoate

formamide

(R)-pantothenate

3-deoxy-D-manno-octulosonate 8-phosphate

5-amino-6-(D-ribitylamino)uracil

β-nicotinate D-ribonucleotide

2-dehydropantoate

2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate

isochorismate

(R)-4'-phosphopantothenoyl-L-cysteine

(R)-4'-phosphopantothenate

preuroporphyrinogen

porphobilinogen

oxalosuccinate

4-pyridoxolactone

α-D-glucosamine 1-phosphate

shikimate 3-phosphate

(2S)-2-amino-3-oxo-4-phosphooxybutanoate

H₂

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-amino-6-(5-phospho-D-ribitylamino)uracil

N-succinyl-L,L-2,6-diaminopimelate

quinolinate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

(R)-mevalonate

(R)-5-phosphomevalonate

N⁵-carboxyaminoimidazole ribonucleotide

L-arginino-succinate

AMP

ADP

GDP

GMP

ATP

IMP

dADP

dATP

GTP

dGDP

dGTP

5'-deoxyadenosine

ITP

dIMP

dITP

XMP

XTP

adenylo-succinate

dIDP

IDP

hypoxanthine

2'-deoxyguanosine

2'-deoxyadenosine

dGMP

dAMP

adenine

guanine

uracil

preQ₁

dCDP

dUDP

dTDP

dTTP

dCTP

dUTP

dCMP

dTMP

dUMP

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

β-nicotinamide D-ribonucleotide

CMP

UMP

UDP

CDP

CTP

UTP

NADH

NADPH

NAD⁺

NADP⁺

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine

UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-galactose

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramate

UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-α-D-galactofuranose

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-mannosaminuronate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-glucosamine

GDP-α-D-mannose

dTDP-4-dehydro-β-L-rhamnose

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

dTDP-β-L-rhamnose

CMP-3-deoxy-β-D-manno-octulosonate

inosine

xanthosine

adenosine

guanosine

2'-deoxyuridine

2'-deoxycytidine

thymidine

cytidine

uridine

orotate

(S)-1-pyrroline-5-carboxylate

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydromonapterin

7,8-dihydroneopterin

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydroneopterin 3'-phosphate

7,8-dihydropteroate

7,8-dihydrofolate monoglutamate

5,6,7,8-tetrahydrofolate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

6,7-dimethyl-8-(1-D-ribityl)lumazine

riboflavin

FAD

FMN

adenosylcobalamin

cob(I)alamin

hypoglycin B

L-α-amino-ε-keto-pimelate

L-citrulline

L-methionine

L-cysteine

glycine

L-serine

L-tyrosine

L-lysine

L-histidine

L-glutamine

L-glutamate

L-aspartate

L-threonine

L-alanine

L-arginine

L-leucine

L-valine

L-isoleucine

L-asparagine

S-adenosyl-L-methionine

L-homocysteine

S-adenosyl-L-homocysteine

hypoglycin A

L-glutamate-5-semialdehyde

L-aspartate 4-semialdehyde

S-sulfo-L-cysteine

L-ornithine

L-homoserine

meso-diaminopimelate

L-selenocysteine

L-isoglutamine

L,L-diaminopimelate

L-cystathionine

L-aspartyl-4-phosphate

formyl-L-isoglutamine

N-formimino-L-glutamate

N-carbamoyl-L-aspartate

L-2-amino-3-oxobutanoate

3-phospho-L-serine

D-alanine

D-glutamate

β-alanine

3-demethylubiquinol-8

menaquinol-8

ubiquinol-8

demethylmenaquinol-8

4-aminobenzoate

trans,octacis-decaprenyl phosphate

(2E,6E)-farnesyl diphosphate

mono-trans,octa-cis-decaprenyl diphosphate

di-trans,octa-cis-undecaprenyl phosphate

all-trans-octaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

dioleoyl phosphatidate

1-oleoyl-2-lyso-glycerone phosphate

1-oleoyl-sn-glycerol 3-phosphate

acetyl-CoA

2-methylacetoacetyl-CoA

3'-dephospho-CoA

(2S)-methylsuccinyl-CoA

succinyl-CoA

malonyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

(E)-2-methylcrotonoyl-CoA

2-methylbutanoyl-CoA

(S)-methylmalonyl-CoA

(R)-methylmalonyl-CoA

oleoyl-CoA

propanoyl-CoA

butanoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

4-methyl-3-oxoadipyl-CoA

3-oxoadipyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

crotonyl-CoA

aldehydo-D-ribose

β-D-ribofuranose

α-D-ribofuranose

glycolaldehyde

N-acetyl-α-D-mannosamine

N-acetyl-α-D-glucosamine 1-phosphate

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

5-phospho-α-D-ribose 1-diphosphate

D-erythrose 4-phosphate

4-phospho-D-erythronate

α-D-ribose-1-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-arabinose 5-phosphate

α-D-glucopyranose 1-phosphate

α-D-mannose 1-phosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-fructose 1,6-bisphosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-mannopyranose 6-phosphate

D-glyceraldehyde 3-phosphate

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

a peptidoglycan dimer (E. faeciums)

a peptidoglycan dimer (S. aureus)

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide)

a peptidoglycan dimer (mycobacteria)

a peptidoglycan with L,D cross-links (mycobacteria)

a peptidoglycan with D,D cross-links (mycobacteria)

a peptidoglycan tetramer with a D,D cross-link (Enterococcus faecium)

a peptidoglycan with D,D cross-link (S. aureus)

a peptidoglycan dimer (meso-diaminopimelate containing)

a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

formaldehyde

acetaldehyde

acetate

(R)-pantoate

butanoate

glyoxylate

pyruvate

2-oxoglutarate

2-oxobutanoate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

formate

(R)-lactate

(2R,3S)-2-methylisocitrate

chorismate

fumarate

succinate

(S)-malate

cis-aconitate

cis-2-methylaconitate

D-threo-isocitrate

nicotinamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

ethanol

methanol

agmatine

putrescine

spermidine

dehydrospermidine

2-aminoprop-2-enoate

2-iminopropanoate

(2Z)-2-aminobut-2-enoate

glutathione

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

hydrogencarbonate

thiosulfate

selenide

superoxide

phosphate

diphosphate

triphosphate

Fe²⁺

H⁺

ammonium

thiamine

nicotinate

pyridoxine 5'-phosphate

pyridoxal 5'-phosphate

pyridoxamine 5'-phosphate

pyridoxal

pyridoxamine

pyridoxine

(R)-NADHX

(S)-NADHX

coenzyme A

preQ₀

5,10-methenyltetrahydrofolate mono-L-glutamate

L-cysteinylglycine

D-alanyl-D-alanine

2-iminosuccinate

2-iminobutanoate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

sn-glycerol 3-phosphate

oxygen

hydrogen sulfide

protoporphyrin IX

protoporphyrinogen IX

uroporphyrinogen-III

coproporphyrinogen I

uroporphyrinogen-I

protoheme

adenosylcobinamide

cob(I)inamide

adenosyl-cob(III)yrinate a,c-diamide

cob(I)yrinate a,c-diamide

DNA with lesion