an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

5-hydroxyindole thiazolidine carboxylate

ammonia

1-piperideine 6-carboxylate

S-ribosyl-L-homocysteine

autoinducer 2

4-amino-2-methyl-5-pyrimidinemethanol

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

L-arginino-succinate

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

3-hydroxypropanoate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

5-amino-6-(5-phospho-D-ribitylamino)uracil

carbon monoxide

H₂

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

(2S)-2-isopropyl-3-oxosuccinate

(R)-4-phosphopantoate

(2R,3S)-3-methylmalate

citraconate

2-dehydro-3-deoxy-D-gluconate 6-phosphate

dialurate

5,6-dimethylbenzimidazole

(R)-1-amino-2-propanol O-2-phosphate

4-imidazolone-5-propanoate

urocanate

4-amino-4-deoxychorismate

N-(5-phosphoribosyl)-anthranilate

anthranilate

3-deoxy-D-arabino-heptulosonate 7-phosphate

shikimate

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

3-dehydroquinate

3-dehydroshikimate

2-dehydro-3-deoxy-D-gluconate

(S)-3-methyl-2-oxopentanoate

(S)-2-acetolactate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-aceto-2-hydroxybutanoate

formamide

2-dehydropantoate

γ-butyrobetaine

3-methyl-2-oxobutanoate

(2S)-2-isopropylmalate

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

8-amino-7-oxononanoate

(S)-2-amino-6-oxohexanoate

7,8-diaminopelargonate

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

prenyl diphosphate

4-methyl-2-oxopentanoate

pseudouridine 5'-phosphate

(E)-2-benzylidenesuccinyl-CoA

(E)-4-coumaroyl-CoA

2,3-didehydroadipyl-CoA

β-nicotinate D-ribonucleotide

L-selenocystathionine

α-D-glucosamine 1-phosphate

itaconate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

2-(α-hydroxyethyl)thiamine diphosphate

xanthine

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate

2-succinylbenzoate

(S)-dihydroorotate

acetoacetate

5-deoxy-α-ribose 1-phosphate

N-succinyl-L,L-2,6-diaminopimelate

prephenate

4-aminobutanoate

succinate semialdehyde

3-oxopropanoate

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

oxalosuccinate

hydrogen selenide

O-acetyl-L-serine

selenophosphate

5-hydroxytryptophol

indole-3-glycol

indole-3-glycol aldehyde

isobutanol

3-methylbutanol

3-methylbutanal

2-methylbutanol

2-methylbutanal

2-phenylethanol

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

S-adenosyl 3-(methylsulfanyl)propylamine

S-methyl-5'-thioadenosine

thiamine phosphate

thiamine diphosphate

citrate

hydroxypyruvate

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

(lipoyl)adenylate

hydrogen peroxide

orotidine 5'-phosphate

4,8,12-trimethyltridecanoyl-CoA

3-oxopristanoyl-CoA

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

3'-phosphoadenylyl-sulfate

urea

α-ribazole

α-ribazole 5'-phosphate

1-deoxy-L-glycero-tetrulose 4-phosphate

5-amino-6-(D-ribitylamino)uracil

porphobilinogen

preuroporphyrinogen

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

glycerone phosphate

enol-phenylpyruvate

oxaloacetate

imidazole acetaldehyde

4-imidazoleacetate

5-hydroxyindole acetaldehyde

5-hydroxyindole acetate

3-methoxy-4-hydroxyphenylglycolaldehyde

3,4-dihydroxyphenylacetaldehyde

prop-2-ynal

propynoate

D-glucurono-6,3-lactone

4-acetamidobutanal

4-acetamidobutanoate

dimethylsulfoniopropanoate

(L-threonylcarbamoyl)adenylate

O-ureido-L-homoserine

1,4-dihydroxy-2-naphthoate

4'-phosphopantetheine

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

nicotinate adenine dinucleotide

dihydroxyacetone

arsenite

(S)-1-phenylethanol

hexulose 6-phosphate

isopentenyl diphosphate

butanoyl phosphate

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

CO₂

carbamoyl phosphate

3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA

3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA

2-carboxymethyl-3-hydroxyphenylpropanoyl-CoA

benzoylsuccinyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-hydroxypropanoyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

phosphoenolpyruvate

2-O-(6-phospho-α-D-mannosyl)-D-glycerate

(R)-mevalonate

(R)-5-phosphomevalonate

acrylamide

acrylate

4-guanidinobutyramide

4-guanidinobutanoate

(indol-3-yl)acetamide

propionamide

H₂O

2-oxopent-4-enoate

(S)-4-hydroxy-2-oxopentanoate

nitric oxide

superoxide

N-acetyl-β-neuraminate

dimethyl sulfide

methionol

3-(methylsulfanyl)propanal

3-dimethylsulfoniopropionaldehyde

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

L-cysteate

3-sulfopyruvate

sulfate

nitrite

nitrate

thiosulfate

selenide

selenate

arsenate

hydrogencarbonate

phosphate

triphosphate

diphosphate

K⁺

H⁺

ammonium

Fe²⁺

Hg²⁺

Mg²⁺

trimethyl sulfonium

2-iminopropanoate

2-aminoprop-2-enoate

agmatine

putrescine

dehydrospermidine

spermidine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

acetamide

nicotinamide

24-hydroxy-3-oxocholest-4-en-26-oyl-CoA

3,24-dioxocholest-4-en-26-oyl-CoA

(25S)-3-oxocholest-4-en-26-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

(+)-7-epi-jasmonate

(indol-3-yl)acetate

2-methylbutanoyl-CoA

3-hydroxypropanoyl-CoA

acryloyl-CoA

4-hydroxybutanoyl-CoA

malonyl-CoA

γ-butyrobetainyl-CoA

L-carnitinyl-CoA

methylacrylyl-CoA

(2E,5Z)-tetradecenoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

3-hydroxyisovaleryl-CoA

(E)-2-methylcrotonoyl-CoA

2-trans,6-cis-tridecadienoyl-CoA

(3E)-undec-2-enoyl-CoA

(3R)-hydroxy-undecanoyl-CoA

2-trans-6-trans-tridecadienoyl-CoA

2-trans, 4-trans-undecadienoyl-CoA

2-trans-nonenoyl-CoA

(3R)-hydroxy-nonanoyl-CoA

itaconyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

succinyl-CoA

(+)-7-epi-jasmonoyl-CoA

3'-dephospho-CoA

2-methylacetoacetyl-CoA

acetyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxooctanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxohexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxobutanoyl)-CoA

(3R)-hydroxy, 6-cis-tridecenoyl-CoA

6-cis, 3-oxo-tridecenoyl-CoA

(3R)-hydroxy, 6-trans-tridecenoyl-CoA

6-trans-3-oxo-tridecenoyl-CoA

(3R)-hydroxy, 4-trans-undecenoyl-CoA

4-trans-3-oxo-undecenoyl-CoA

(3R)-hydroxy- 5-cis, 7-trans-tetradecadienoyl-CoA

5-cis, 7-trans-3-oxo-tetradecadienoyl-CoA

(3R)-hydroxy-5-trans-dodecenoyl-CoA

(5E)-3-oxo-dodec-5-enoyl-CoA

(3S)-hydroxyadipyl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

(S)-methylmalonyl-CoA

(R)-methylmalonyl-CoA

crotonyl-CoA

phytenoyl-CoA

(2E)-octadec-2-enoyl-CoA

(2E)-dec-2-enoyl-CoA

(2E)-oct-2-enoyl-CoA

oleoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(S)-3-hydroxydecanoyl-CoA

(S)-3-hydroxyhexanoyl-CoA

(S)-3-hydroxyoctanoyl-CoA

(S)-3-hydroxy-(5Z)-tetradecenoyl-CoA

(S)-3-hydroxyhexadecanoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

(3R)-3-hydroxyoctadecanoyl-CoA

(Z)-15-tetracosenoyl-CoA

propanoyl-CoA

octanoyl-CoA

decanoyl-CoA

stearoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

3-oxoadipyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

3-oxodecanoyl-CoA

3-oxohexanoyl-CoA

3-oxooctanoyl-CoA

3-oxo-(5Z)-tetradecenoyl-CoA

3-oxo-palmitoyl-CoA

(S)-3-hydroxy-isobutanoyl-CoA

D-glucono-1,5-lactone

FAD

FMN

FMNH₂

(S)-NADHX

(R)-NADHX

NADPH

NADH

NADP⁺

NAD⁺

demethylmenaquinol-8

(R)-lipoate

coenzyme A

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

7,8-dihydrofolate monoglutamate

riboflavin

nicotinate

pyridoxal 5'-phosphate

pyridoxamine 5'-phosphate

L-carnitine

menadione

(S)-1-pyrroline-5-carboxylate

precorrin-2

precorrin-1

sirohydrochlorin

cob(I)alamin

adenosylcobalamin

6,7-dimethyl-8-(1-D-ribityl)lumazine

adenine

guanine

2'-deoxyadenosine

2'-deoxyguanosine

xanthosine

adenosine

hypoxanthine

dAMP

dGMP

dIMP

dITP

dATP

dGTP

dIDP

dADP

dGDP

IDP

GDP

ADP

IMP

XMP

GMP

AMP

XTP

ITP

GTP

ATP

dUMP

dTMP

dTDP

dTTP

orotate

dCMP

dCDP

CDP

dUDP

UDP

uracil

dCTP

dUTP

CTP

UTP

UDP-α-D-galactofuranose

UDP-α-D-glucose

UDP-α-D-galactose

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-glucosamine

dTDP-α-D-glucose

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

cytidine

uridine

thymidine

2'-deoxycytidine

2'-deoxyuridine

thymine

UMP

CMP

salicylaldehyde

3-hexaprenyl-4-hydroxybenzoate

4-hydroxybenzoate

4-tyrosol

ethylbenzene

indole

(indol-3-yl)acetaldehyde

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

menadiol

3,4-dihydroxyphenylglycol

3,4-dihydroxyphenylglycolaldehyde

3,4-dihydroxymandelate

3,4-dihydroxyphenylacetate

salicylate

benzoate

4-aminobenzoate

3-methoxy-4-hydroxyphenylglycol

vanillyl mandelate

benzaldehyde

(4-hydroxyphenyl)acetaldehyde

phenylacetaldehyde

(15Z)-tetracosenoate

butanoate

octanoate

decanoate

(2E,6E)-farnesoate

oleate

linoleate

α-linolenate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

phytenate

stearate

pristanate

palmitate

D-gluconate

(R)-pantoate

acetate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

glyoxylate

2-oxobutanoate

4-(methylsulfanyl)-2-oxobutanoate

2-oxoglutarate

pyruvate

L-cysteine

glycine

L-tyrosine

L-threonine

L-serine

L-asparagine

L-glutamine

L-lysine

L-arginine

L-histidine

L-aspartate

L-glutamate

L-tryptophan

L-phenylalanine

D-alanine

L-aspartyl-4-phosphate

seleno-L-homocysteine

N-formimino-L-glutamate

N-acetyl-L-ornithine

N-acetyl-L-citrulline

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

O-acetyl-L-homoserine

L-citrulline

L-glutamate-5-semialdehyde

L-aspartate 4-semialdehyde

O-succinyl-L-homoserine

S-sulfo-L-cysteine

L-homoserine

O-phospho-L-homoserine

L-homocysteine

L-ornithine

L-canaline

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

S-(4-hydroxy-nonenal-3-yl)-L-cysteine

meso-diaminopimelate

L-selenocysteine

L-methionine

L-leucine

L-isoleucine

L-valine

L-alanine

L-proline

L,L-diaminopimelate

L-cystathionine

β-alanine

chorismate

fumarate

succinate

(S)-malate

D-glucarate

cis-homoaconitate

(2R)-homocitrate

cis-aconitate

(2R,3S)-2-methylisocitrate

D-threo-isocitrate

4-hydroxybutanoate

(S)-lactate

(R)-lactate

(R)-glycerate

formate

propanoate

diacetyl

acetone

(2E,6E)-farnesal

α-D-glucopyranose

β-D-glucopyranose

β-D-galactopyranose

α-D-galactopyranose

butan-1-al

formaldehyde

1-propanal

isobutanal

1-octanal

acetaldehyde

(R)-lactaldehyde

phytenal

myo-inositol

1D-myo-inositol 1-monophosphate

1D-myo-inositol 3-monophosphate

butan-1-ol

ethanol

propan-1-ol

phytol

glycerol

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

(2E,6E)-farnesyl diphosphate

phytyl diphosphate

3-nonaprenyl-4-hydroxybenzoate

3-heptaprenyl-4-hydroxybenzoate

3-decaprenyl-4-hydroxybenzoate

3-octaprenyl-4-hydroxybenzoate

di-trans,octa-cis-undecaprenyl phosphate

all-trans-nonaprenyl diphosphate

all-trans-hexaprenyl diphosphate

all-trans-heptaprenyl diphosphate

all-trans-decaprenyl diphosphate

all-trans-octaprenyl diphosphate

geranylgeranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

maltotriose

maltotetraose

maltopentaose

maltoheptaose

maltohexaose

α-maltose

sucrose

N-acetyl-α-D-glucosamine 1-phosphate

N-acetyl-β-D-mannosamine

β-D-fructofuranose

GDP-α-D-mannose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

α-D-galactose 1-phosphate

β-D-glucopyranose 1-phosphate

α-D-mannose 1-phosphate

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

D-altronate

adenylo-succinate

5'-deoxyadenosine

cyclic-AMP

adenosylcobyrate

cob(II)yrinate a,c-diamide

cob(I)yrinate a,c-diamide

adenosyl-cob(III)yrinate a,c-diamide

cob(I)inamide

adenosylcobinamide

adenosyl-cobinamide phosphate

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

Mg-protoporphyrin

protoheme

nitrous oxide

uroporphyrinogen-I

uroporphyrinogen-III

protoporphyrin IX

siroheme

Hg⁰

hydrogen sulfide

oxygen

sn-glycerol 1-phosphate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

(2R)-2,3-dihydroxy-3-methylbutanoate

S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine

(R)-citramalate

(S)-citramalate

(S)-methylmalonate-semialdehyde

5,10-methenyltetrahydrofolate mono-L-glutamate

2-octaprenylphenol