an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

3-deoxy-D-manno-octulosonate 8-phosphate

3-deoxy-α-D-manno-2-octulosonate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

isopentenyl diphosphate

orotidine 5'-phosphate

3-dehydroshikimate

shikimate

3-dehydroquinate

3-deoxy-D-arabino-heptulosonate 7-phosphate

itaconate

5-enolpyruvoyl-shikimate 3-phosphate

thiamine diphosphate

shikimate 3-phosphate

7,8-diaminopelargonate

2-(α-hydroxyethyl)thiamine diphosphate

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

8-amino-7-oxononanoate

pseudouridine 5'-phosphate

dethiobiotin

N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate

S-acetyldihydrolipoamide

H₂O

phosphoenolpyruvate

carbamoyl phosphate

lipoamide

dihydrolipoamide

(S)-dihydroorotate

CO₂

2-C-methyl-D-erythritol 4-phosphate

(indol-3-yl)pyruvate

ammonia

5-amino-6-(5-phospho-D-ribosylamino)uracil

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

hydrogen peroxide

oxaloacetate

octadecanal

coproporphyrinogen III

6-phospho D-glucono-1,5-lactone

D-gluconate 6-phosphate

glycerone phosphate

5-aminolevulinate

(S)-4-amino-5-oxopentanoate

1-deoxy-L-glycero-tetrulose 4-phosphate

S-ribosyl-L-homocysteine

pimelate

5-(methylsulfanyl)-α-D-ribose

prenyl diphosphate

S-methyl-5'-thioadenosine

(S)-2,3,4,5-tetrahydrodipicolinate

5-amino-6-(5-phospho-D-ribitylamino)uracil

lipid IV_A

5-amino-6-(D-ribitylamino)uracil

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

thiamine phosphate

4-methyl-2-oxopentanoate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

4-prenylphlorisobutyrophenone

salicyl alcohol

pimeloyl-CoA

(lipoyl)adenylate

lipid A disaccharide (E. coli)

lipid X

N-acetyl-D-muramate 6-phosphate

1,6-anhydro-N-acetyl-β-muramate

α-D-glucosamine 1-phosphate

methylsalicylate

preuroporphyrinogen

porphobilinogen

pseudouridine

2-iminoacetate

oxygen

ubiquinone-8

glycolaldehyde

α-D-glucopyranose

β-D-glucopyranose

D-glyceraldehyde

hydrogencarbonate

superoxide

phosphate

diphosphate

H⁺

ammonium

Cd²⁺

Fe²⁺

trimethyl sulfonium

(2E,6E)-farnesyl diphosphate

protoporphyrin IX

protoporphyrinogen IX

coproporphyrinogen I

uroporphyrinogen-I

uroporphyrinogen-III

protoheme

dimethyl sulfide

5-(2-hydroxyethyl)-4-methylthiazole

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

5,10-methenyltetrahydrofolate mono-L-glutamate

L-α-amino-ε-keto-pimelate

L-leucine

L-phenylalanine

L-methionine

L-tryptophan

L-alanine

glycine

L-serine

L-tyrosine

L,L-diaminopimelate

L-lysine

L-arginine

L-aspartyl-4-phosphate

L-glutamate

L-glutamine

L-aspartate

N-carbamoyl-L-aspartate

S-adenosyl-L-methionine

L-homocysteine

S-adenosyl-L-homocysteine

L-aspartate 4-semialdehyde

L-homoserine

meso-diaminopimelate

D-alanine

D-glutamate

guanine

adenine

cytosine

uracil

thymine

preQ₁

ATP

GTP

ITP

XMP

IMP

AMP

GMP

ADP

IDP

GDP

dGTP

dATP

dGMP

dAMP

dADP

dGDP

guanosine

inosine

adenosine

xanthosine

2'-deoxyguanosine

2'-deoxyinosine

2'-deoxyadenosine

CTP

UTP

orotate

dTTP

dUMP

dUTP

dCTP

dTDP

dTMP

dCMP

UDP

dUDP

CDP

dCDP

UMP

CMP

uridine

cytidine

thymidine

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramate

UDP-α-D-glucose

UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine

UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

FMN

riboflavin

FAD

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydromonapterin

7,8-dihydroneopterin

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydroneopterin 3'-phosphate

7,8-dihydrofolate monoglutamate

5,6,7,8-tetrahydrofolate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

6,7-dimethyl-8-(1-D-ribityl)lumazine

preQ₀

4-methylphenol

4-hydroxybenzoate

salicyl-6-hydroxy-2-cyclohexene-on-oyl

6-hydroxy-2-cyclohexen-one-carboxylate

benzyl-6-hydroxy-2-cyclohexene-on-oyl

benzyl alcohol

salicylate

phenol

demethylmenaquinol-8

menaquinol-8

ubiquinol-8

chorismate

fumarate

succinate

(S)-malate

2-oxoglutarate

pyruvate

glyoxylate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

palmitate

(R)-lactate

acetate

formate

1-oleoyl-2-lyso-glycerone phosphate

D-alanyl-D-alanine

L-alanyl-γ-D-glutamyl-meso-diaminopimelate

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

(indol-3-yl)acetate

methyl (indol-3-yl)acetate

methanol

(3R)-linalool

(3S)-linalool

heptadecane

agmatine

cadaverine

all-trans-retinol

coenzyme A

(R)-lipoate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

adenylo-succinate

5'-deoxyadenosine

β-nicotinamide D-ribonucleotide

NADP⁺

NAD⁺

NADPH

NADH

ADP-α-D-glucose

GDP-α-D-mannose

CMP-3-deoxy-β-D-manno-octulosonate

1-(β-D ribofuranosyl)nicotinamide

β-D-fructofuranose

N-acetyl-β-D-glucosamine

N-acetyl-α-D-glucosamine 1-phosphate

sucrose

maltotetraose

maltotriose

α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IV_A

α-Kdo-(2→6)-lipid IV_A

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

sucrose 6^F-phosphate

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

a peptidoglycan dimer (E. faeciums)

a peptidoglycan dimer (S. aureus)

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

a peptidoglycan tetramer with a D,D cross-link (Enterococcus faecium)

a peptidoglycan with D,D cross-link (S. aureus)

GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)

a peptidoglycan dimer (meso-diaminopimelate containing)

5-phospho-α-D-ribose 1-diphosphate

D-erythrose 4-phosphate

D-sedoheptulose 7-phosphate

1-deoxy-D-xylulose 5-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-arabinose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

(R)-NADHX

(S)-NADHX

phlorisovalerophenone

all-trans-retinyl palmitate

geranyl diphosphate

4-prenylphlorisovalerophenone

deoxycohumulone

deoxyhumulone

di-trans,octa-cis-undecaprenyl phosphate

di-trans,octa-cis-undecaprenyl diphosphate

geranylgeranyl diphosphate

dioleoyl phosphatidate

1-oleoyl-sn-glycerol 3-phosphate

1-C16:0-α,ω-dicarboxyl-2-lysophosphatidate

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

itaconyl-CoA

succinyl-CoA

acetyl-CoA

malonyl-CoA

3'-dephospho-CoA

oleoyl-CoA

hexadecanedioyl-CoA

palmitoyl-CoA