an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

ammonia

1-piperideine 6-carboxylate

pseudouridine

(S)-5-amino-3-oxohexanoate

(3S,5S)-3,5-diaminohexanoate

2-amino-3-carboxymuconate-6-semialdehyde

5-(methylsulfanyl)-2,3-dioxopentyl 1-phosphate

acetyl phosphate

1,6-anhydro-N-acetyl-β-muramate

N-acetyl-D-muramate 6-phosphate

dialurate

2-oxoadipate

(S)-2-amino-6-oxohexanoate

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate

2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate

2-oleoylglycerol

oxalosuccinate

L-arogenate

propanoyl phosphate

4-amino-4-deoxychorismate

(S)-2,3,4,5-tetrahydrodipicolinate

2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl 1-phosphate

1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one

(L-threonylcarbamoyl)adenylate

carbonic acid

4-fumaryl-acetoacetate

acetoacetate

citrate

coproporphyrinogen III

L-β-lysine

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

2-C-methyl-D-erythritol 4-phosphate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

thiamine diphosphate

1,4-dihydroxy-2-naphthoate

4'-phosphopantetheine

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

shikimate

3-dehydroshikimate

3-dehydroquinate

5-deoxy-α-ribose 1-phosphate

S-methyl-5'-thioadenosine

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

α-D-glucosamine 1-phosphate

3-phosphooxypyruvate

(R)-1-amino-2-propanol O-2-phosphate

5,6-dimethylbenzimidazole

α-ribazole 5'-phosphate

α-ribazole

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

thiamine phosphate

β-D-ribosylnicotinate

2-dehydropantoate

(R)-pantothenate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

(2S)-2-isopropylmalate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

3-methyl-2-oxobutanoate

N¹-(5-phospho-β-D-ribosyl)glycinamide

N⁵-carboxyaminoimidazole ribonucleotide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

L-histidinol phosphate

histidinal

histidinol

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

nicotinate adenine dinucleotide

hydrogen selenide

(R)-1-aminopropan-2-ol

1-deoxy-L-glycero-tetrulose 4-phosphate

5-amino-6-(D-ribitylamino)uracil

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

orotidine 5'-phosphate

(S)-dihydroorotate

O-ureido-L-homoserine

canavaninosuccinate

L-canavanine

L-arginino-succinate

γ-L-glutamyl 5-phosphate

oxaloacetate

prenyl diphosphate

isopentenyl diphosphate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

pseudouridine 5'-phosphate

β-nicotinate D-ribonucleotide

hydrogen peroxide

carbamoyl phosphate

5-phospho-β-D-ribosylamine

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

anthranilate

N-(5-phosphoribosyl)-anthranilate

phosphoenolpyruvate

3-deoxy-D-arabino-heptulosonate 7-phosphate

prephenate

enol-phenylpyruvate

CO₂

O-acetyl-L-serine

glycerone phosphate

quinolinate

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

H₂O

L-homocysteine

phenylacetate

cobalt-factor III

cobalt-precorrin-3

cobalt-sirohydrochlorin

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-5B

cobalt-precorrin-6A

cobalt-precorrin-4

cobalt-precorrin-5A

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobyrinate

adenosylcobalamin 5'-phosphate

adenosyl-cobinamide phosphate

adenosylcobinamide-GDP

adenosylcobyrate

cob(I)yrinate a,c-diamide

adenosyl-cob(III)yrinate a,c-diamide

cob(I)alamin

adenosylcobalamin

cob(I)inamide

adenosylcobinamide

protoheme

protoporphyrin IX

uroporphyrinogen-III

protoporphyrinogen IX

hydrogen sulfide

oxygen

sn-glycerol 3-phosphate

2-O-(α-D-mannosyl)-3-phospho-D-glycerate

2-O-(α-D-mannosyl)-D-glycerate

2,3-diphospho-D-glycerate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

(2R)-2,3-dihydroxy-3-methylbutanoate

1-oleoyl-2-lyso-glycerone phosphate

5,10-methenyltetrahydrofolate mono-L-glutamate

superoxide

dimethyl sulfide

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

L-cysteate

3-sulfopyruvate

ammonium

H⁺

Fe²⁺

Co²⁺

trimethyl sulfonium

thiosulfate

hydrogencarbonate

phosphate

triphosphate

diphosphate

(2Z)-2-aminobut-2-enoate

choline

sn-glycero-3-phosphocholine

sn-glycero-3-phosphoethanolamine

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

nicotinamide

(S)-3-aminobutanoyl-CoA

2-trans,6-cis-tridecadienoyl-CoA

(3R)-hydroxy, 6-cis-tridecenoyl-CoA

(3E)-undec-2-enoyl-CoA

(3R)-hydroxy-undecanoyl-CoA

2-trans-6-trans-tridecadienoyl-CoA

(3R)-hydroxy, 6-trans-tridecenoyl-CoA

2-trans, 4-trans-undecadienoyl-CoA

(3R)-hydroxy, 4-trans-undecenoyl-CoA

2-trans-nonenoyl-CoA

(3R)-hydroxy-nonanoyl-CoA

2-trans, 5-cis, 7-trans-tetradecatrienoyl-CoA

(3R)-hydroxy- 5-cis, 7-trans-tetradecadienoyl-CoA

(2E,5E)-dodeca-2,5-dienoyl-CoA

(3R)-hydroxy-5-trans-dodecenoyl-CoA

(R)-2-hydroxyglutaryl-CoA

(E)-glutaconyl-CoA

phenylacetyl-CoA

linoleoyl-CoA

α-linolenoyl-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

3'-dephospho-CoA

acetyl-CoA

crotonyl-CoA

phytenoyl-CoA

(2E)-octadec-2-enoyl-CoA

oleoyl-CoA

(3R)-3-hydroxyoctadecanoyl-CoA

(Z)-15-tetracosenoyl-CoA

butanoyl-CoA

propanoyl-CoA

decanoyl-CoA

octanoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

hexadecanedioyl-CoA

acetoacetyl-CoA

FMNH₂

FMN

FAD

(S)-NADHX

(R)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

menaquinol-7

demethylmenaquinol-13

demethylmenaquinol-12

demethylmenaquinol-11

demethylmenaquinol-10

demethylmenaquinol-6

demethylmenaquinol-9

demethylmenaquinol-7

demethylmenaquinol-8

coenzyme A

7,8-dihydrofolate monoglutamate

5,6,7,8-tetrahydrofolate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

nicotinate

riboflavin

pyridoxal 5'-phosphate

(S)-1-pyrroline-5-carboxylate

precorrin-1

precorrin-2

sirohydrochlorin

6,7-dimethyl-8-(1-D-ribityl)lumazine

7,8-dihydroneopterin 3'-phosphate

7,8-dihydroneopterin

7,8-dihydroneopterin 3'-triphosphate

6-(hydroxymethyl)-7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydropteroate

adenine

guanine

2'-deoxyadenosine

2'-deoxyguanosine

guanosine

inosine

xanthosine

adenosine

hypoxanthine

dAMP

dGMP

dITP

dGTP

dATP

dIDP

dGDP

dADP

IDP

GDP

ADP

GMP

XMP

IMP

AMP

ITP

GTP

ATP

dCMP

dTTP

dCTP

dUTP

dUDP

UDP

dCDP

CDP

dTDP

dUMP

dTMP

orotate

uracil

UTP

CTP

UDP-α-D-glucose

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-glucosamine

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

cytidine

uridine

CMP

UMP

preQ₁

preQ₀

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

4-aminobenzoate

chorismate

succinate

fumarate

L-aspartate

(S)-malate

(1R,2S)-homoisocitrate

cis-homoaconitate

cis-aconitate

(2R)-homocitrate

D-threo-isocitrate

(R)-lactate

propanoate

acetate

formate

pyruvate

butanoate

decanoate

octanoate

(15Z)-tetracosenoate

oleate

linoleate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

α-linolenate

phytenate

palmitate

pristanate

(R)-pantoate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

4-(methylsulfanyl)-2-oxobutanoate

glyoxylate

2-oxobutanoate

2-oxoglutarate

L-α-amino-ε-keto-pimelate

L-2-aminoadipate

L-serine

(R)-β-lysine

β-alanine

L-alanine

L-leucine

L-proline

glycine

L-glutamine

L-glutamate

L-lysine

L-histidine

L-arginine

L-cysteine

L-tyrosine

L-threonine

L-phenylalanine

L-tryptophan

D-alanine

L-saccharopine

L-aspartyl-4-phosphate

L-threonine 3-O-phosphate

3-phospho-L-serine

N-acetyl-L-ornithine

N-acetyl-L-methionine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

L-citrulline

L-valine

L-isoleucine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

S-sulfo-L-cysteine

O-phospho-L-homoserine

L-homoserine

L-aspartate 4-semialdehyde

L-glutamate-5-semialdehyde

L-ornithine

meso-diaminopimelate

L-selenocysteine

L-methionine

L,L-diaminopimelate

methylglyoxal

diacetyl

glycolaldehyde

acetaldehyde

aldehydo-D-ribose

β-D-ribofuranose

α-D-ribofuranose

1-(oleoyl)-sn-glycero-3-phosphoethanolamine

1-oleoyl-sn-glycerol 3-phosphate

1-C16:0-α,ω-dicarboxyl-2-lysophosphatidate

dioleoyl phosphatidate

(2E,6E)-farnesyl diphosphate

all-trans-tridecaprenyl diphosphate

all-trans-dodecaprenyl diphosphate

all-trans-undecaprenyl diphosphate

all-trans-decaprenyl diphosphate

all-trans-hexaprenyl diphosphate

all-trans-nonaprenyl diphosphate

all-trans-heptaprenyl diphosphate

all-trans-octaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

1-(β-D ribofuranosyl)nicotinamide

sucrose

N-acetyl-α-D-muramoyl-L-alanine(1-)

N-acetylmuramate

N-acetyl-α-D-glucosamine 1-phosphate

N-acetyl-β-D-glucosamine

β-D-fructofuranose

GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala

GDP-α-D-mannose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

D-sedoheptulose 7-phosphate

5-phospho-α-D-ribose 1-diphosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-erythrose 4-phosphate

β-D-fructose 1,6-bisphosphate

D-tagatofuranose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

β-D-ribose 5-phosphate

α-D-ribose 5-phosphate

α-D-ribose-1-phosphate

β-D-glucopyranose 1-phosphate

α-D-mannose 1-phosphate

1-(5-phospho-β-D-ribosyl)-AMP

pppGpp

ppGpp

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-ATP

adenylo-succinate

β-nicotinamide D-ribonucleotide

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

cyclic di-3',5'-guanylate

L-alanyl-γ-D-glutamyl-meso-diaminopimelate

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

D-alanyl-D-alanine

2-iminobutanoate

2-iminosuccinate