an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

S-methyl-5'-thioadenosine

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-methyl-2-oxobutanoate

3-phosphooxypyruvate

histidinol

histidinal

5-phospho-β-D-ribosylamine

L-arginino-succinate

(S)-3-methyl-2-oxopentanoate

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

5-amino-6-(5-phospho-D-ribitylamino)uracil

phosphoenolpyruvate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

1,3-propanediol

3-hydroxypropanal

itaconate

coproporphyrinogen III

oxaloacetate

citrate

N-methylhydantoin

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

hydrogen selenide

O-acetyl-L-serine

1-deoxy-L-glycero-tetrulose 4-phosphate

5-amino-6-(D-ribitylamino)uracil

5-enolpyruvoyl-shikimate 3-phosphate

(S)-dihydroorotate

hydrogenobyrinate

O-ureido-L-homoserine

CDP-glycerol

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

D-erythro-imidazole-glycerol-phosphate

salicyl alcohol

methylsalicylate

α-ribazole

α-ribazole 5'-phosphate

3-ureidopropanoate

3-deoxy-D-arabino-heptulosonate 7-phosphate

shikimate

shikimate 3-phosphate

oxalosuccinate

N¹-(5-phospho-β-D-ribosyl)glycinamide

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

(E)-2-benzylidenesuccinyl-CoA

2-carboxymethyl-3-hydroxyphenylpropanoyl-CoA

3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA

(E)-4-coumaroyl-CoA

2,3-didehydroadipyl-CoA

isopentenyl diphosphate

prenyl diphosphate

4-prenylphlorisobutyrophenone

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

(2S)-2-isopropylmalate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

carbamoyl phosphate

orotidine 5'-phosphate

imidazole acetol-phosphate

L-histidinol phosphate

anthranilate

N-(5-phosphoribosyl)-anthranilate

glycerone phosphate

3-dehydroquinate

3-dehydroshikimate

preuroporphyrinogen

4-methylumbelliferyl glucoside

scopolin

cis-coumarinic acid-β-D-glucoside

β-D-fructose 2,6-bisphosphate

4-fumaryl-acetoacetate

acetoacetate

4-pyridoxolactone

N-acetylglutamyl-phosphate

prephenate

4,8,12-trimethyltridecanoyl-CoA

3-oxopristanoyl-CoA

S-adenosyl 3-(methylsulfanyl)propylamine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

thiamine phosphate

isochorismate

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

H₂

carbon monoxide

nicotinate adenine dinucleotide

(R)-pantothenate

(R)-4'-phosphopantothenate

2-dehydro-3-deoxy-D-gluconate

hydroxypyruvate

4-amino-4-deoxychorismate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

xanthine

2-(4-hydroxyphenyl)-2-oxoacetate

4-hydroxybenzaldehyde

phenylglyoxylate

2-phosphoglycolate

glycolate

CO₂

H₂O

enol-phenylpyruvate

ammonia

5,6-dimethylbenzimidazole

dialurate

(R)-1-amino-2-propanol O-2-phosphate

β-nicotinate D-ribonucleotide

5'-deoxy-5'-fluoroadenosine

5-fluoro-5-deoxy-D-ribose 1-phosphate

5'-chloro-5'-deoxyadenosine

5-chloro-5-deoxyribose 1-phosphate

allantoate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

(25S)-3-oxocholest-4-en-26-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

methyl (indol-3-yl)acetate

(indol-3-yl)acetate

(+)-7-epi-jasmonate

all-trans-retinyl palmitate

D-glucono-1,5-lactone

2-methylbutanoyl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

succinyl-CoA

itaconyl-CoA

2-methylacetoacetyl-CoA

acetyl-CoA

(2E,4E)-tetradeca-2,4-dienoyl-CoA

(3E)-tetradec-3-enoyl-CoA

2-trans, 4-cis-undecadienoyl-CoA

(3E)-undec-3-enoyl-CoA

methylacrylyl-CoA

(2E,5Z)-tetradecenoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA

(3S)-hydroxyadipyl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

3-hydroxyisovaleryl-CoA

(E)-2-methylcrotonoyl-CoA

2-trans,6-cis-tridecadienoyl-CoA

(3R)-hydroxy, 6-cis-tridecenoyl-CoA

(3E)-undec-2-enoyl-CoA

(3R)-hydroxy-undecanoyl-CoA

2-trans-6-trans-tridecadienoyl-CoA

(3R)-hydroxy, 6-trans-tridecenoyl-CoA

2-trans, 4-trans-undecadienoyl-CoA

(3R)-hydroxy, 4-trans-undecenoyl-CoA

2-trans-nonenoyl-CoA

(3R)-hydroxy-nonanoyl-CoA

(+)-7-epi-jasmonoyl-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

crotonyl-CoA

phytenoyl-CoA

(2E)-octadec-2-enoyl-CoA

trans-Δ², cis-Δ⁴-decadienoyl-CoA

(2E)-dec-2-enoyl-CoA

(2E)-oct-2-enoyl-CoA

oleoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(S)-3-hydroxydecanoyl-CoA

(S)-3-hydroxyoctanoyl-CoA

(S)-3-hydroxy-(5Z)-tetradecenoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

(3R)-3-hydroxyoctadecanoyl-CoA

(Z)-15-tetracosenoyl-CoA

propanoyl-CoA

octanoyl-CoA

decanoyl-CoA

stearoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

(S)-3-hydroxy-isobutanoyl-CoA

FAD

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

molybdopterin

coenzyme A

MoO₂-molybdopterin cofactor

guanylyl molybdenum cofactor

7,8-dihydrofolate monoglutamate

5,6,7,8-tetrahydrofolate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

thiamine

riboflavin

nicotinate

all-trans-retinol

pyridoxal

(S)-1-pyrroline-5-carboxylate

guanine

adenine

2'-deoxyadenosine

2'-deoxyguanosine

2'-deoxyinosine

inosine

guanosine

xanthosine

adenosine

hypoxanthine

GDP

ADP

GMP

AMP

IMP

XMP

ATP

GTP

uracil

dTTP

5,6-dihydrouracil

5,6-dihydrothymine

dTDP

dTMP

dUMP

orotate

CDP

dCMP

dCDP

dCTP

dUTP

CTP

UTP

UDP

cytidine

uridine

2'-deoxycytidine

thymidine

2'-deoxyuridine

UMP

CMP

UDP-α-D-glucose

dTDP-α-D-glucose

dTDP-β-L-rhamnose

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

dTDP-4-dehydro-β-L-rhamnose

cobalt-precorrin-3

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-4

cobalt-precorrin-5A

precorrin-1

precorrin-6A

cobalt-precorrin-5B

cobalt-precorrin-6A

precorrin-4

precorrin-5

precorrin-2

precorrin-3A

precorrin-6B

precorrin-7

precorrin-8x

sirohydrochlorin

cobyrinate

adenosylcobalamin

hydantoin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

7,8-dihydroneopterin 2'-phosphate

7,8-dihydroneopterin 3'-phosphate

7,8-dihydroneopterin

6-(hydroxymethyl)-7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

molybdopterin adenine dinucleotide

cyclic pyranopterin phosphate

7,8-dihydroneopterin 2',3'-cyclic phosphate

7,8-dihydroneopterin 3'-triphosphate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

scopoletin

coumarin

4-methylumbelliferone

taxiphyllin

linustatin

neolinustatin

linamarin

lotaustralin

hydrogen cyanide

2-hydroxy-2-methylpropanenitrile

(2R)-2-hydroxy-2-methylbutanenitrile

2-[(1R,6S)-1,6-dihydroxycyclohexa-2,4-dien-1-yl]acetyl-coA

salicyl-6-hydroxy-2-cyclohexene-on-oyl

6-hydroxy-2-cyclohexen-one-carboxylate

coumarinate

salicylate

4-aminobenzoate

benzaldehyde

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

D-gluconate

acetate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

2-oxobutanoate

2-oxoglutarate

pyruvate

L-tryptophan

L-histidine

L-tyrosine

D-proline

D-aspartate

L-aspartyl-4-phosphate

N-carbamoylglycine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

3-phospho-L-serine

L-citrulline

L-homoserine

S-sulfo-L-cysteine

L-homocysteine

L-canaline

L-ornithine

O-phospho-L-homoserine

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

L-glutamate-5-semialdehyde

meso-diaminopimelate

L-lysine

L-selenocysteine

L-methionine

L-leucine

L-isoleucine

glycine

L-serine

L-threonine

L-asparagine

L-arginine

L-proline

L-glutamine

L-glutamate

L-aspartate

L-cysteine

L-cystathionine

N-carbamoylsarcosine

β-alanine

chorismate

succinate

fumarate

3-(carbamoylamino)-2-methylpropanoate

D-threo-isocitrate

(R)-glycerate

formate

octanoate

decanoate

(15Z)-tetracosenoate

oleate

linoleate

α-linolenate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

phytenate

stearate

pristanate

palmitate

glycolaldehyde

D-glyceraldehyde

α-D-glucopyranose

β-D-glucopyranose

α-D-galactopyranose

β-D-galactopyranose

α-D-ribofuranose

acetaldehyde

(S)-lactaldehyde

methanol

(3R)-linalool

(3S)-linalool

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

(2E,6E)-farnesyl diphosphate

geranyl diphosphate

geranylgeranyl diphosphate

6-O-α-mycolyl-trehalose 6-phosphate

α, α'-trehalose 6-α-mycolate

6-O-cis-methoxy-mycolyl-trehalose 6-phosphate

trehalose-cis-methoxy-mono-mycolate

6-O-trans-methoxy-mycolyl-trehalose 6-phosphate

trehalose-trans-methoxy-mono-mycolate

6-O-cis-keto-mycolyl-trehalose 6-phosphate

trehalose-cis-keto-mono-mycolate

6-O-trans-keto-mycolyl-trehalose 6-phosphate

trehalose-trans-keto-mono-mycolate

phlorisovalerophenone

deoxyhumulone

4-prenylphlorisovalerophenone

deoxycohumulone

β-D-fructofuranose

α,α-trehalose 6-phosphate

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

5-phospho-α-D-ribose 1-diphosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-erythrose 4-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

α-D-ribose 5-phosphate

β-D-ribose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

L-fuculose 1-phosphate

β-D-glucopyranose 1-phosphate

maltotriose

maltotetraose

maltopentaose

maltoheptaose

maltohexaose

α-maltose

sucrose

α,α-trehalose

β-D-cellobiose

adenylo-succinate

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

8-oxo-dGTP

8-oxo-dGMP

β-nicotinamide D-ribonucleotide

2-iminobutanoate

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

cob(II)yrinate c-monoamide

cobalt-factor III

cobalt-sirohydrochlorin

cob(II)yrinate a,c-diamide

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

adenosylcobyrate

adenosyl-cobinamide phosphate

adenosyl-cob(III)yrinate a,c-diamide

cob(I)yrinate a,c-diamide

protoheme

protoporphyrinogen IX

uroporphyrinogen-III

protoporphyrin IX

oxygen

hydrogen sulfide

Hg⁰

sn-glycerol 1-phosphate

sn-glycerol 3-phosphate

2,3-diphospho-D-glycerate

3-phospho-D-glycerate

2-phospho-D-glycerate

(S)-ureidoglycine

5,10-methenyltetrahydrofolate mono-L-glutamate

thiocyanate

4-methyl-5-(2-phosphooxyethyl)thiazole

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

(2R)-3-sulfolactate

(2R)-phospho-3-sulfolactate

Fe³⁺

H⁺

ammonium

K⁺

Co²⁺

Fe²⁺

Hg²⁺

molybdate

hydrogencarbonate

thiosulfate

sulfite

hydrogensulfite

phosphate

triphosphate

diphosphate

(2Z)-2-aminobut-2-enoate

agmatine

spermidine

putrescine