an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

H₂O

glycerone phosphate

phosphoenolpyruvate

nicotinate adenine dinucleotide

(R)-4'-phosphopantothenate

(R)-pantothenate

CO₂

3-deoxy-α-D-manno-2-octulosonate

3-deoxy-D-manno-octulosonate 8-phosphate

propanoyl phosphate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

glycolate

(S)-dihydroorotate

hydrogen peroxide

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

quinolinate

β-nicotinate D-ribonucleotide

L-β-lysine

acetoacetate

N¹-(5-phospho-β-D-ribosyl)glycinamide

5-phospho-β-D-ribosylamine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

formate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

N⁵-carboxyaminoimidazole ribonucleotide

orotidine 5'-phosphate

carboxyphosphate

carbamoyl phosphate

DNA without lesion

4-amino-4-deoxychorismate

2-phosphoglycolate

lipid IV_A

1,4-dihydroxy-2-naphthoate

1-deoxy-L-glycero-tetrulose 4-phosphate

(2S)-2-amino-3-oxo-4-phosphooxybutanoate

3-amino-1-hydroxyacetone 1-phosphate

4-phosphooxy-L-threonine

coproporphyrinogen III

lipid A disaccharide (E. coli)

lipid X

FK-506

31-O-desmethylFK-506

(4Z)-2-oxohept-4-enedioate

(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

3-methyl-2-oxobutanoate

3-phosphooxypyruvate

4-oxoglutaramate

1-piperideine 6-carboxylate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

aminoacetone

1,2-dihydro-β-NADP

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

enol-phenylpyruvate

ammonia

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

bisorganyltrisulfane

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

2-C-methyl-D-erythritol 4-phosphate

β-D-ribosylnicotinate

N-ethylammeline

deethylsimazine

acetyl phosphate

butanoyl phosphate

7-carboxy-7-deazaguanine

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

4'-phosphopantetheine

(indol-3 yl)acetyl-CoA

(indol-3-yl)pyruvate

N-succinyl-2-amino-6-ketopimelate

(S)-2,3,4,5-tetrahydrodipicolinate

(R)-4'-phosphopantothenoyl-L-cysteine

thiamine diphosphate

thiamine phosphate

5-amino-6-(D-ribitylamino)uracil

8-amino-7-oxononanoate

pimeloyl-CoA

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

isopentenyl diphosphate

prenyl diphosphate

5-methylcytosine

4-methyl-2-oxopentanoate

(S)-3-methyl-2-oxopentanoate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

2-iminoacetate

3-dehydroshikimate

shikimate

4-imidazolone-5-propanoate

urocanate

norspermidine

carboxynorspermidine

(S)-2-amino-6-oxohexanoate

oxaloacetate

4-aminobutanoate

prephenate

2-dehydropantoate

chloramphenicol

xanthine

glutathione disulfide

3-dehydroquinate

formamide

(S)-2-aceto-2-hydroxybutanoate

(R)-2,3-dihydroxy-3-methylpentanoate

N-succinyl-L,L-2,6-diaminopimelate

autoinducer 2

S-ribosyl-L-homocysteine

2-amino-3-carboxymuconate-6-semialdehyde

D-alanyl-D-alanine

carbamate

L-α-amino-ε-keto-pimelate

L-glutamine

L-glutamate

L-isoleucine

L-valine

L-tryptophan

L-alanine

L-aspartate

L-serine

L-lysine

glycine

L-proline

L-leucine

L-threonine

L-tyrosine

L-histidine

L-cysteine

L-methionine

L-homocysteine

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

L-aspartate 4-semialdehyde

L-homoserine

L-glutamate-5-semialdehyde

meso-diaminopimelate

L-aspartyl-4-phosphate

L-2-amino-3-oxobutanoate

L-saccharopine

O-acetyl-L-homoserine

trans-4-hydroxy-L-proline

formyl-L-isoglutamine

N-formimino-L-glutamate

N-carbamoyl-L-aspartate

3-phospho-L-serine

L,L-diaminopimelate

L-isoglutamine

D-alanine

D-glutamate

β-alanine

(R)-β-lysine

protocatechuate

4-aminobenzoate

(R)-pantoate

orotate

acetate

(S)-1-pyrroline-5-carboxylate

pristanate

palmitate

stearate

decanoate

laurate

7-hydroxylaurate

octanoate

butanoate

18-hydroxyoleate

16-hydroxypalmitate

18-hydroxystearate

phytenate

(15Z)-tetracosenoate

oleate

linoleate

α-linolenate

4-hydroxybutanoate

(R)-lactate

propanoate

pyruvate

2-oxoglutarate

glyoxylate

2-oxobutanoate

3-phenyl-2-oxopropanoate

3-oxoadipate

3-carboxy-cis,cis-muconate

chorismate

α,ω-9Z-octadecenedioate

fumarate

succinate

(S)-malate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

α-Kdo-(2→6)-lipid IV_A

trans,octacis-decaprenyl phosphate

3-octaprenyl-4-hydroxybenzoate

3-heptaprenyl-4-hydroxybenzoate

3-nonaprenyl-4-hydroxybenzoate

3-decaprenyl-4-hydroxybenzoate

3-hexaprenyl-4-hydroxybenzoate

di-trans,octa-cis-undecaprenyl phosphate

all-trans-octaprenyl diphosphate

all-trans-heptaprenyl diphosphate

all-trans-nonaprenyl diphosphate

all-trans-decaprenyl diphosphate

all-trans-hexaprenyl diphosphate

1-(β-D ribofuranosyl)nicotinamide

1-O-acetyl-α-maltose

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

ADP-α-D-glucose

GDP-α-D-mannose

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

dTDP-α-D-glucose

dTDP-4-dehydro-β-L-rhamnose

dTDP-β-L-rhamnose

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-α-D-galactose

UDP-α-D-glucose

UDP-α-D-galactofuranose

UDP-N-acetyl-α-D-muramate

UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine

UDP-α-D-glucuronate

UDP-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

CMP-3-deoxy-β-D-manno-octulosonate

5-phospho-α-D-ribose 1-diphosphate

D-erythrose 4-phosphate

D-sedoheptulose 7-phosphate

α-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 6-phosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

5-fluoro-5-deoxy-D-ribose 1-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

D-arabinofuranose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-xylulose 5-phosphate

L-xylulose 5-phosphate

D-ribulose 5-phosphate

L-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

sucrose 6^G-phosphate

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

β-D-fructofuranose

α-D-galactopyranose

β-D-galactopyranose

β-D-glucopyranose

α-D-glucopyranose

D-glyceraldehyde

ethanol

methanol

methylglyoxal

acetaldehyde

formaldehyde

caldariellaquinone

4-hydroxybenzoate

urate

caldariellaquinol

3-demethylubiquinol-10

3-demethylubiquinol-8

3-demethylubiquinol-9

3-demethylubiquinol-7

demethylmenaquinol-8

menaquinol-8

ubiquinol-10

ubiquinol-8

ubiquinol-9

ubiquinol-7

4-methylphenol

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

adenine

guanine

AMP

GMP

IMP

XMP

ATP

GTP

ADP

GDP

dADP

dGDP

dATP

dGTP

dGMP

dAMP

hypoxanthine

adenosine

inosine

guanosine

xanthosine

2'-deoxyguanosine

2'-deoxyadenosine

2'-deoxyinosine

6-carboxy-5,6,7,8-tetrahydropterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

tetrahydromethanopterin

7,8-dihydroneopterin 3'-triphosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydropteroate

5,10-methylene-tetrahydromethanopterin

7,8-dihydrofolate monoglutamate

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

reduced riboflavin

FMNH₂

riboflavin

FMN

6,7-dimethyl-8-(1-D-ribityl)lumazine

uracil

thymine

cytosine

preQ₁

isoguanine

CTP

UDP

dCDP

dCMP

CDP

dTMP

dUMP

UTP

dCTP

dUTP

dUDP

5,6-dihydrouracil

5,6-dihydrothymine

dTDP

dTTP

UMP

CMP

uridine

cytidine

2'-deoxyuridine

2'-deoxycytidine

thymidine

5-fluorouracil

adenosylcobalamin

precorrin-2

precorrin-1

coenzyme A

adenylo-succinate

5'-deoxyadenosine

8-oxo-GTP

ppGpp

pppGpp

8-oxo-dGTP

5-chloro-5-deoxyribose 1-phosphate

5'-chloro-5'-deoxyadenosine

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

β-nicotinamide D-ribonucleotide

5-hydroxy-CTP

2-hydroxy-dATP

cyclic di-3',5'-guanylate

NAD⁺

NADP⁺

NADH

NADPH

5'-deoxy-5'-fluoroadenosine

5-fluorocytosine

(S)-NADHX

(R)-NADHX

pyridoxal 5'-phosphate

pyridoxine 5'-phosphate

pyridoxamine 5'-phosphate

cob(I)alamin

testosterone

17-β-hydroxy-5-α-androstan-3-one

progesterone

(25S)-3-oxocholest-4-en-26-oyl-CoA

(25S)-3-oxocholest-4-en-26-oate

cholest-4-en-3-one

coprostanone

cortisone

4,5α-dihydrocortisone

5-α-pregnane-3,20-dione

cholate

glycocholate

succinyl-CoA

acetyl-CoA

linoleoyl-CoA

α-linolenoyl-CoA

isobutanoyl-CoA

3'-dephospho-CoA

4-hydroxybutanoyl-CoA

(E)-glutaconyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

oleoyl-CoA

acetoacetyl-CoA

16-hydroxypalmitoyl-CoA

palmitoyl-CoA

stearoyl-CoA

18-hydroxyoleoyl-CoA

18-hydroxystearoyl-CoA

pristanoyl-CoA

decanoyl-CoA

lauroyl-CoA

7-hydroxylauroyl-CoA

octanoyl-CoA

propanoyl-CoA

butanoyl-CoA

(Z)-15-tetracosenoyl-CoA

phytenoyl-CoA

crotonyl-CoA

(R)-methylmalonyl-CoA

(S)-methylmalonyl-CoA

S-(hydroxymethyl)glutathione

glutathione

(R)-S-lactoylglutathione

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

4-methyl-5-(2-phosphooxyethyl)thiazole

methanethiol

S-sulfanylglutathione

2-aminoprop-2-enoate

2-iminopropanoate

superoxide

hydroxyl radical

hydrogencarbonate

OH^-

chloride

phosphonate

phosphate

diphosphate

triphosphate

Fe³⁺

Mg²⁺

Fe²⁺

Zn²⁺

H⁺

ammonium

2-chloroacetate

chloramphenicol 3-acetate

preQ₀

2-octaprenylphenol

ω-saturated C55 dolichol phosphate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

sn-glycerol 3-phosphate

β-D-mannosyl-(C55 ω-saturated dolichyl phosphate)

2-iminosuccinate

hydrogen sulfide

oxygen

Mg-protoporphyrin

protoporphyrin IX

protoporphyrinogen IX

uroporphyrinogen-III

protoheme

DNA with lesion