an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

dialurate

(R)-1-amino-2-propanol O-2-phosphate

5-amino-6-(D-ribitylamino)uracil

propanoyl phosphate

6-phospho D-glucono-1,5-lactone

D-gluconate 6-phosphate

2-phosphoglycolate

7-carboxy-7-deazaguanine

L-canavanine

(S)-dihydroorotate

quinolinate

histidinal

S-Inosyl-L-homocysteine

anthranilate

N-(5-phosphoribosyl)-anthranilate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

5-phospho-α-D-ribose 1,2-cyclic phosphate

preuroporphyrinogen

carbon monoxide

ammonia

enol-phenylpyruvate

ethanolamine

(S)-2-acetolactate

α-D-glucosamine 1-phosphate

N⁵-carboxyaminoimidazole ribonucleotide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

norspermidine

(S)-2-amino-6-oxohexanoate

3-oxopropanoate

S-methyl-5-thio-α-D-ribose 1-phosphate

D-erythro-imidazole-glycerol-phosphate

4-amino-4-deoxychorismate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

orotidine 5'-phosphate

2-dehydropantoate

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

(R)-4'-phosphopantothenoyl-L-cysteine

coproporphyrinogen III

O-acetyl-L-serine

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

carbonic acid

pimeloyl-CoA

xanthine

carboxynorspermidine

2-keto-D-gluconate

2,5-didehydro-D-gluconate

3-deoxy-D-arabino-heptulosonate 7-phosphate

2-C-methyl-D-erythritol 4-phosphate

(lipoyl)adenylate

histidinol

L-arginino-succinate

canavaninosuccinate

5,6-dimethylbenzimidazole

H₂

O-ureido-L-homoserine

acetyl phosphate

5-dehydro-4-deoxy-D-glucarate

β-nicotinate D-ribonucleotide

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

4-prenylphlorisobutyrophenone

selenophosphate

oxaloacetate

3-dehydroquinate

(S)-mandelate

(R)-mandelate

urea

2-iminoacetate

(R)-2,3-dihydroxy-3-methylpentanoate

coenzyme B

CoB-CoM heterodisulfide

dihydromethanophenazine

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

porphobilinogen

thiamine phosphate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

α-ribazole 5'-phosphate

1,2-dihydro-β-NADP

(2S)-2-isopropylmalate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

(2S)-2-isopropyl-3-oxosuccinate

3-ethylmalate

2-oxovalerate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

isopentenyl diphosphate

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

(4S)-4-hydroxy-2-oxoheptanedioate

succinate semialdehyde

3-deoxy-α-D-manno-2-octulosonate

glycolate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

selenodiglutathione

phosphoenolpyruvate

hydroxypyruvate

hydrogen peroxide

imidazole acetol-phosphate

L-histidinol phosphate

DNA without lesion

1-piperideine 6-carboxylate

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

carbamoyl phosphate

carboxyphosphate

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

oxalosuccinate

nicotinate adenine dinucleotide

CO₂

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

glycerone phosphate

(R)-pantothenate

(R)-4'-phosphopantothenate

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

4-methyl-2-oxopentanoate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

thiamine diphosphate

(S)-2-aceto-2-hydroxybutanoate

2,5-dioxopentanoate

glutathione disulfide

prenyl diphosphate

hydrogen selenide

prephenate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

8-amino-7-oxononanoate

α-D-ribose-1-methylphosphonate 5-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

γ-L-glutamyl 5-phosphate

shikimate

β-D-ribosylnicotinate

4'-phosphopantetheine

3-dehydroshikimate

α-ribazole

methanophenazine

H₂O

3-deoxy-D-manno-octulosonate 8-phosphate

1-deoxy-L-glycero-tetrulose 4-phosphate

(S)-3-methyl-2-oxopentanoate

3-methyl-2-oxobutanoate

glutathioselenol

DNA with lesion

4-methylphenol

L-homocysteine

phenylacetate

hydrogen cyanide

adenosylcobalamin

cob(I)alamin

adenosyl-cobinamide phosphate

cob(I)yrinate a,c-diamide

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobyrinate

cobalt-precorrin-5A

cobalt-sirohydrochlorin

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

cobalt-precorrin-2

cobalt-precorrin-4

Mg-protoporphyrin

protoheme

uroporphyrinogen-I

protoporphyrinogen IX

protoporphyrin IX

uroporphyrinogen-III

siroheme

oxygen

hydrogen sulfide

2-iminosuccinate

2-iminopropanoate

2-iminobutanoate

2-chloroacetate

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

(R)-glycerate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

(2R)-2,3-dihydroxy-3-methylbutanoate

(S)-methylmalonate-semialdehyde

(S)-4-hydroxymandelate

(R)-4-hydroxymandelate

2-octaprenylphenol

preQ₀

5'-deoxy-5'-fluoroadenosine

5-fluoro-5-deoxy-D-ribose 1-phosphate

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

5-chloro-5-deoxyribose 1-phosphate

5'-chloro-5'-deoxyadenosine

Fe³⁺

H⁺

ammonium

Fe²⁺

Mo²⁺

Co²⁺

Ni²⁺

Mg²⁺

sulfate

hydrogensulfite

nitrate

thiosulfate

molybdate

selenide

sulfite

selenite

selenate

OH^-

superoxide

hydrogencarbonate

phosphonate

phosphate

diphosphate

triphosphate

chloride

hydroxyl radical

(2E,6E)-farnesyl diphosphate

pristanate

1-oleoyl-2-palmitoyl-phosphatidylglycerol

2-aminoprop-2-enoate

(2Z)-2-aminobut-2-enoate

agmatine

N¹-acetylspermidine

N-acetylputrescine

N¹-acetylspermine

spermidine

spermine

putrescine

S-(hydroxymethyl)glutathione

glutathione

thiocyanate

methanethiol

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

L-cysteate

3-sulfopyruvate

coenzyme M

dodecyl sulfate

succinyl-CoA

3'-dephospho-CoA

linoleoyl-CoA

α-linolenoyl-CoA

isobutanoyl-CoA

malonyl-CoA

(R)-2-hydroxyglutaryl-CoA

(E)-glutaconyl-CoA

phenylacetyl-CoA

acetyl-CoA

phytenoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

oleoyl-CoA

7-hydroxylauroyl-CoA

16-hydroxypalmitoyl-CoA

18-hydroxyoleoyl-CoA

18-hydroxystearoyl-CoA

(Z)-15-tetracosenoyl-CoA

propanoyl-CoA

lauroyl-CoA

octanoyl-CoA

decanoyl-CoA

palmitoyl-CoA

stearoyl-CoA

pristanoyl-CoA

methane

nicotinate

riboflavin

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5,10-methylene-tetrahydromethanopterin

tetrahydromethanopterin

pyridoxal

pyridoxal 5'-phosphate

pyridoxine

pyridoxine 5'-phosphate

pyridoxamine 5'-phosphate

pyridoxamine

FMNH₂

FMN

(R)-NADHX

(S)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

guanosine 2',3'-cyclic monophosphate

adenosine 2',3'-cyclic monophosphate

pppGpp

ppGpp

adenosine 3'-monophosphate

guanosine 3'-monophosphate

dGTP

dATP

IDP

isoguanine

8-oxo-dGTP

8-oxo-GTP

adenylo-succinate

GTP

2'-deoxyadenosine

2'-deoxyguanosine

2'-deoxyinosine

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

IMP

dADP

dGDP

GDP

GMP

AMP

ATP

5'-deoxyadenosine

ADP

dIDP

hypoxanthine

XMP

ITP

dITP

guanosine

inosine

adenosine

xanthosine

uridine

cytidine

2'-deoxyuridine

2'-deoxycytidine

cytidine 2',3'-cyclic monophosphate

uridine 2'3'-cyclic monophosphate

cyclic di-3',5'-guanylate

2-hydroxy-dATP

5-hydroxy-CMP

5-hydroxy-CTP

dTTP

dCTP

dUTP

UTP

CTP

dTMP

dUMP

dCMP

UMP

CMP

dUDP

dCDP

dTDP

CDP

UDP

β-nicotinamide D-ribonucleotide

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

uridine 3'-monophosphate

cytidine-3'-monophosphate

GDP-α-D-mannuronate

GDP-α-D-mannose

preQ₁

uracil

adenine

guanine

CMP-3-deoxy-β-D-manno-octulosonate

UDP-α-D-glucose

CDP-α-D-glucose

dTDP-α-D-glucose

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramate

UDP-α-D-glucuronate

UDP-α-D-galactofuranose

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-α-D-galactose

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-glucosamine

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

CDP-4-dehydro-6-deoxy-α-D-glucose

(R)-lipoate

coenzyme A

(S)-1-pyrroline-5-carboxylate

precorrin-4

precorrin-5

precorrin-8x

precorrin-3A

precorrin-1

precorrin-2

sirohydrochlorin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

6-(hydroxymethyl)-7,8-dihydropterin

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydroneopterin 3'-triphosphate

6-carboxy-5,6,7,8-tetrahydropterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

orotate

urate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

protocatechuate

6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol

all trans-decaprenyl-2-methoxy-6-1,4-benzoquinol

4-aminobenzoate

methanol

ethanol

1-dodecanol

glycerol

1-(β-D ribofuranosyl)nicotinamide

N-acetyl-α-D-glucosamine 1-phosphate

D-glyceraldehyde

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

D-erythrose 4-phosphate

D-sedoheptulose 7-phosphate

5-phospho-α-D-ribose 1-diphosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-arabinofuranose 5-phosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

5-amino-4-imidazolecarboxyamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

carbamate

L-serine

L-cysteine

L-tyrosine

L-threonine

L-glutamine

L-asparagine

glycine

L-arginine

L-histidine

L-lysine

L-aspartate

L-glutamate

L-methionine

L-phenylalanine

L-alanine

L-proline

L-tryptophan

L-valine

L-isoleucine

L-leucine

β-alanine

D-glutamate

D-alanine

L-cystathionine

L,L-diaminopimelate

L-aspartyl-4-phosphate

L-ornithine

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

L-saccharopine

N-acetyl-L-glutamate

trans-4-hydroxy-L-proline

O-acetyl-L-homoserine

L-citrulline

O-succinyl-L-homoserine

L-canaline

O-phospho-L-homoserine

L-homoserine

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

L-aspartate 4-semialdehyde

L-glutamate-5-semialdehyde

meso-diaminopimelate

chorismate

succinate

fumarate

(S)-malate

α,ω-9Z-octadecenedioate

D-galactarate

3-carboxy-cis,cis-muconate

D-threo-isocitrate

3-oxoadipate

3-phenyl-2-oxopropanoate

pyruvate

2-oxobutanoate

2-oxoglutarate

glyoxylate

acetate

formate

propanoate

decanoate

7-hydroxylaurate

laurate

octanoate

4-hydroxybutanoate

18-hydroxystearate

16-hydroxypalmitate

18-hydroxyoleate

(15Z)-tetracosenoate

linoleate

palmitate

oleate

α-linolenate

stearate

phytenate

(R)-pantoate

D-alanyl-D-alanine

phlorisovalerophenone

deoxyhumulone

deoxycohumulone

4-prenylphlorisovalerophenone

geranyl diphosphate

trans,octacis-decaprenyl phosphate

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

di-trans,octa-cis-undecaprenyl phosphate

geranylgeranyl diphosphate

all-trans-octaprenyl diphosphate

3-octaprenyl-4-hydroxybenzoate

diacetyl

formaldehyde

acetaldehyde