an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

α-D-ribose 1,5-bisphosphate

carbon monoxide

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

(2S)-2-isopropylmalate

2-oxovalerate

3-ethylmalate

4-methyl-2-oxopentanoate

(2S)-2-isopropyl-3-oxosuccinate

anthranilate

N-(5-phosphoribosyl)-anthranilate

N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate

3-dehydroshikimate

3-dehydroquinate

shikimate

3-deoxy-D-arabino-heptulosonate 7-phosphate

2,5-didehydro-D-gluconate

2-keto-D-gluconate

ADP-L-glycero-β-D-manno-heptose

ADP-D-glycero-β-D-manno-heptose

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

thiamine phosphate

S-methyl-5'-thioadenosine

hydrogenobyrinate

preuroporphyrinogen

porphobilinogen

5-aminolevulinate

(S)-4-amino-5-oxopentanoate

carbonic acid

histidinal

hydrogen peroxide

thiamine diphosphate

N-acetyl-D-muramate 6-phosphate

1,6-anhydro-N-acetyl-β-muramate

carboxyphosphate

N⁵-carboxyaminoimidazole ribonucleotide

2-amino-3-carboxymuconate-6-semialdehyde

formamide

aminoacetone

1,2-dihydro-β-NADP

pyruvic oxime

enol-phenylpyruvate

dethiobiotin

H₂O

CO₂

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

3-methyl-2-oxobutanoate

(S)-3-methyl-2-oxopentanoate

(R)-2,3-dihydroxy-3-methylpentanoate

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

phosphoenolpyruvate

quinolinate

β-nicotinate D-ribonucleotide

glycolate

O-acetyl-L-serine

dimethylamine

N²-succinylglutamate

glycerone phosphate

ethanolamine

prephenate

(2Z,4E)-2-hydroxyhexa-2,4-dienedioate

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

L-histidinol phosphate

urea

L-canavanine

D-galactosamine-6-phosphate

N-acetyl-D-galactosamine 6-phosphate

7,8-diaminopelargonate

butanoyl phosphate

carbamoyl phosphate

oxaloacetate

hydroxylamine

ammonia

N-acetyl-β-glucosaminylamine

N⁴-(β-N-acetyl-D-glucosaminyl)-L-asparagine

isopentenyl diphosphate

(indol-3 yl)acetyl-CoA

(indol-3-yl)pyruvate

O-ureido-L-homoserine

N-carbamoyl-D-phenylglycine

D-phenylhydantoin

citrate

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

2-maleylacetate

xanthine

2-dehydropantoate

(R)-pantothenate

α-ribazole 5'-phosphate

5,6-dimethylbenzimidazole

acetoacetate

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

urocanate

4-imidazolone-5-propanoate

histidinol

urea-1-carboxylate

S-adenosyl 3-(methylsulfanyl)propylamine

L-arginino-succinate

canavaninosuccinate

coproporphyrinogen III

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

N¹-(5-phospho-β-D-ribosyl)glycinamide

5-phospho-β-D-ribosylamine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

selenophosphate

4'-phosphopantetheine

(R)-4'-phosphopantothenoyl-L-cysteine

acetyl phosphate

(S)-dihydroorotate

orotidine 5'-phosphate

DNA without lesion

2-C-methyl-D-erythritol 4-phosphate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

nicotinate adenine dinucleotide

3-phosphooxypyruvate

4-amino-4-deoxychorismate

5-amino-6-(D-ribitylamino)uracil

1-deoxy-L-glycero-tetrulose 4-phosphate

prenyl diphosphate

5-(methylsulfanyl)-ribulose 1-phosphate

S-methyl-5-thio-α-D-ribose 1-phosphate

α-D-glucosamine 1-phosphate

(R)-4'-phosphopantothenate

lipid IV_A

3-deoxy-D-manno-octulosonate 8-phosphate

3-deoxy-α-D-manno-2-octulosonate

lipid A disaccharide (E. coli)

lipid X

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

L-cysteinylglycine

D-alanyl-D-alanine

L-alanyl-γ-D-glutamyl-meso-diaminopimelate

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

hypoglycin B

carbamate

L-citrulline

L-cysteine

L-methionine

L-phenylalanine

L-isoleucine

L-glutamate

L-glutamine

L-serine

glycine

L-tyrosine

L-alanine

L-proline

L-arginine

L-aspartate

L-asparagine

L-threonine

L-leucine

L-tryptophan

L-valine

L-histidine

L-glutamate-5-semialdehyde

S-adenosyl-L-methionine

hypoglycin A

L-canaline

L-ornithine

S-adenosyl-L-homocysteine

L-aspartate 4-semialdehyde

L-homoserine

L-homocysteine

O-phospho-L-homoserine

meso-diaminopimelate

L-2-amino-3-oxobutanoate

L-aspartyl-4-phosphate

O-acetyl-L-homoserine

trans-4-hydroxy-L-proline

formyl-L-isoglutamine

N-formimino-L-glutamate

N⁶,N⁶-dimethyl-L-arginine

N-carbamoyl-L-aspartate

3-phospho-L-serine

L,L-diaminopimelate

L-isoglutamine

D-proline

D-glutamate

D-alanine

β-alanine

trans-cinnamate

4-aminobenzoate

acetate

5-chloro-5-deoxy-D-ribonate

(R)-pantoate

orotate

(S)-1-pyrroline-5-carboxylate

laurate

stearate

butanoate

palmitate

1-cis-vaccenoyl-2-palmitoleoyl-sn-glycerol-3-phosphate

1-myristoyl-2-palmitoleoyl-sn-glycerol 3-phosphate

1-palmitoyl-2-palmitoleoyl-sn-glycerol 3-phosphate

1-palmitoyl-2-cis-vaccenoyl phosphatidate

1,2-dicis-vaccenoyl-phosphatidate

(R)-lactate

pyruvate

formate

propanoate

5-chloro-4-hydroxy-2-oxopentanoate

2-oxobutanoate

2-oxoglutarate

3-phenyl-2-oxopropanoate

cis-homoaconitate

(1R,2S)-homoisocitrate

(2R)-homocitrate

cis-aconitate

D-threo-isocitrate

chorismate

(3E)-2-oxohex-3-enedioate

fumarate

succinate

(S)-malate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

α-Kdo-(2→6)-lipid IV_A

(2E,6E)-farnesyl diphosphate

trans,octacis-decaprenyl phosphate

mono-trans,octa-cis-decaprenyl diphosphate

geranyl diphosphate

di-trans,octa-cis-undecaprenyl phosphate

di-trans,octa-cis-undecaprenyl diphosphate

all-trans-heptaprenyl diphosphate

geranylgeranyl diphosphate

1-oleoyl-2-palmitoyl-phosphatidylglycerol

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

1-palmitoyl-2-myristoyl phosphatidate

1,2-dimyristoyl-sn-glycerol 3-phosphate

1-[18-hydroxyoeoyl]-2-[18-hydroxy-lioleoyl]-sn-glycerol 3-phosphate

dioleoyl phosphatidate

1-cis-vaccenoyl-sn-glycerol-3-phosphate

1-palmitoyl-sn-glycerol 3-phosphate

1-myristoyl-sn-glycerol 3-phosphate

1-(18-hydroxyoleoyl)-sn-glycrol 3-phosphate

1-oleoyl-sn-glycerol 3-phosphate

trehalose-cis-keto-mono-mycolate

6-O-cis-keto-mycolyl-trehalose 6-phosphate

α, α'-trehalose 6-α-mycolate

6-O-α-mycolyl-trehalose 6-phosphate

trehalose-trans-keto-mono-mycolate

6-O-trans-keto-mycolyl-trehalose 6-phosphate

trehalose-cis-methoxy-mono-mycolate

6-O-cis-methoxy-mycolyl-trehalose 6-phosphate

trehalose-trans-methoxy-mono-mycolate

6-O-trans-methoxy-mycolyl-trehalose 6-phosphate

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

ADP-α-D-glucose

GDP-4-dehydro-α-D-rhamnose

GDP-α-D-mannose

GDP-α-D-glucose

GDP-β-L-fucose

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine

UDP-α-D-galactose

UDP-α-D-glucose

UDP-α-D-glucuronate

UDP-β-L-threo-pentapyranos-4-ulose

UDP-4-amino-4-deoxy-β-L-arabinopyranose

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

CMP-3-deoxy-β-D-manno-octulosonate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-erythrose 4-phosphate

D-sedoheptulose 7-phosphate

5-phospho-α-D-ribose 1-diphosphate

α-D-mannose 1-phosphate

α-D-glucopyranose 1-phosphate

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-glucopyranose 1-phosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-fructose 1,6-bisphosphate

α-D-glucose 6-phosphate

α-D-ribose-1-phosphate

5-fluoro-5-deoxy-D-ribose 1-phosphate

2-deoxy-α-D-ribose 1-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-arabinofuranose 5-phosphate

D-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

α,α-trehalose 6-phosphate

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

D-ribulose-1,5-bisphosphate

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

a peptidoglycan dimer (E. faecium, tetrapeptide)

a peptidoglycan dimer (E. faeciums)

a peptidoglycan dimer (S. aureus)

a peptidoglycan dimer (mycobacteria)

decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide)

GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-(glycyl)₅-D-alanyl-D-alanine

a peptidoglycan dimer with pentapeptide stem (meso-diaminopimelate containing)

a peptidoglycan dimer with pentapeptide stems (meso-diaminopimelate containing)

D-glyceraldehyde

glycolaldehyde

N-acetylmuramate

N-acetyl-α-D-muramoyl-L-alanine(1-)

N-acetyl-β-D-glucosamine

glycerol

α,α-trehalose

maltopentaose

maltohexaose

maltotetraose

maltoheptaose

maltotriose

ethanol

acetaldehyde

diacetyl

acetone

urate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

adenine

guanine

AMP

IMP

XMP

GMP

ATP

GTP

ADP

GDP

dADP

dGDP

dGTP

dATP

hypoxanthine

adenosine

inosine

guanosine

xanthosine

2'-deoxyinosine

2'-deoxyguanosine

2'-deoxyadenosine

tetrahydromethanopterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydromonapterin

7,8-dihydroneopterin

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydropteroate

5,10-methylene-tetrahydromethanopterin

7,8-dihydrofolate monoglutamate

reduced riboflavin

FMNH₂

riboflavin

FMN

6,7-dimethyl-8-(1-D-ribityl)lumazine

uracil

thymine

preQ₁

dTTP

dTDP

dUDP

UDP

CTP

dCTP

UTP

dUTP

dCDP

dCMP

CDP

dTMP

dUMP

CMP

UMP

uridine

cytidine

2'-deoxyuridine

2'-deoxycytidine

thymidine

cob(I)alamin

adenosylcobalamin

sirohydrochlorin

cobyrinate

precorrin-8x

cobalt-precorrin-2

precorrin-2

precorrin-7

precorrin-6B

cobalt-precorrin-5A

cobalt-precorrin-4

precorrin-1

cobalt-precorrin-6A

cobalt-precorrin-5B

cobalt-precorrin-6B

cobalt-precorrin-8

cobalt-precorrin-7

cobalt-precorrin-3

coenzyme A

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

adenylo-succinate

5-chloro-5-deoxyribose 1-phosphate

5'-chloro-5'-deoxyadenosine

ppGpp

pppGpp

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

cyclic di-3',5'-guanylate

NAD⁺

NADP⁺

NADH

NADPH

(S)-NADPHX

(R)-NADPHX

5'-deoxy-5'-fluoroadenosine

(S)-NADHX

(R)-NADHX

nicotinate

(indol-3-yl)acetate

acetyl-CoA

(E)-glutaconyl-CoA

succinyl-CoA

malonyl-CoA

isobutanoyl-CoA

3'-dephospho-CoA

oleoyl-CoA

palmitoleoyl-CoA

stearoyl-CoA

palmitoyl-CoA

myristoyl-CoA

cis-vaccenoyl-CoA

lauroyl-CoA

propanoyl-CoA

butanoyl-CoA

18-hydroxylinoleoyl-CoA

crotonyl-CoA

(R)-methylmalonyl-CoA

(S)-methylmalonyl-CoA

trans-dienelactone

cis-dienelactone

glutathione

(2R)-phospho-3-sulfolactate

3-sulfopyruvate

L-cysteate

(2R)-3-sulfolactate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

4-methyl-5-(2-phosphooxyethyl)thiazole

methanethiol

spermidine

putrescine

(2Z)-2-aminobut-2-enoate

2-aminoprop-2-enoate

2-iminopropanoate

sn-glycero-3-phosphoethanolamine

glycerophosphoserine

glycerophosphoglycerol

nitrate

hydrogencarbonate

selenate

selenite

selenide

chloride

phosphate

diphosphate

triphosphate

Mg²⁺

Co²⁺

Fe²⁺

Zn²⁺

Mo²⁺

K⁺

ammonium

H⁺

2-chloroacetate

preQ₀

(indole-3-yl)acetonitrile

N-acetyl-β-neuraminate 9-phosphate

N-acetyl-D-mannosamine 6-phosphate

α-D-glucosamine 6-phosphate

(2R)-2,3-dihydroxy-3-methylbutanoate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

sn-glycerol 3-phosphate

2-iminosuccinate

2-iminobutanoate

oxygen

hydrogen sulfide

Mg-protoporphyrin

protoporphyrin IX

uroporphyrinogen-III

uroporphyrinogen-I

protoporphyrinogen IX

siroheme

protoheme

cobalt-sirohydrochlorin

cob(II)yrinate a,c-diamide

cobalt-factor III

cob(II)yrinate c-monoamide

adenosylcobyrate

adenosyl-cob(III)yrinate a,c-diamide

ethylphosphate

DNA with lesion