an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

S-ribosyl-L-homocysteine

autoinducer 2

preuroporphyrinogen

sulfoethylcysteine

2-(sulfomethyl)thiazolidine-4-carboxylate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

(S)-2,3,4,5-tetrahydrodipicolinate

acetyl phosphate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

(2S)-lactyl-2-diphospho-5'-guanosine

β-nicotinate D-ribonucleotide

7,8-didemethyl-8-hydroxy-5-deazariboflavin

oxalate

histidinal

4'-phosphopantetheine

histidinol

α-D-glucosamine 1-phosphate

deethylsimazine

N-ethylammeline

hydrogenobyrinate

L-β-lysine

3-dehydroshikimate

5-enolpyruvoyl-shikimate 3-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

coenzyme α-F₄₂₀-3

N⁵-carboxyaminoimidazole ribonucleotide

shikimate

shikimate 3-phosphate

creatinine

methanophenazine

dihydromethanophenazine

hydrogenobyrinate a,c-diamide

7-carboxy-7-deazaguanine

(R)-2,3-dihydroxy-3-methylpentanoate

porphobilinogen

5-phospho-β-D-ribosylamine

(S)-dihydroorotate

N-(5-phosphoribosyl)-anthranilate

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

3'-phosphoadenylyl-sulfate

2-phosphoglycolate

isopentenyl diphosphate

prenyl diphosphate

1-deoxy-L-glycero-tetrulose 4-phosphate

N-acetyl-L-glutamate 5-semialdehyde

N¹-(5-phospho-β-D-ribosyl)glycinamide

(S)-3-methyl-2-oxopentanoate

pimelate

pimeloyl-CoA

3-phosphooxypyruvate

L-canavanine

coenzyme B

CoB-CoM heterodisulfide

glycolate

quinolinate

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

α-D-ribose 1,5-bisphosphate

hexulose 6-phosphate

(R)-mevalonate

coproporphyrinogen III

nicotinate adenine dinucleotide

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

carbonic acid

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

5-deoxy-α-ribose 1-phosphate

S-methyl-5-thio-α-D-ribose 1-phosphate

5-amino-6-(D-ribitylamino)uracil

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

phosphoenolpyruvate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

anthranilate

3-methyl-2-oxobutanoate

D-erythro-imidazole-glycerol-phosphate

N-acetylglutamyl-phosphate

L-arginino-succinate

O-ureido-L-homoserine

canavaninosuccinate

(2S)-2-isopropylmalate

2-isopropylmaleate

S-adenosyl 3-(methylsulfanyl)propylamine

S-methyl-5'-thioadenosine

carbamoyl phosphate

carboxyphosphate

glycerone phosphate

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

orotidine 5'-phosphate

8-amino-7-oxononanoate

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

7,8-diaminopelargonate

(2R,3S)-3-isopropylmalate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

prephenate

oxaloacetate

selenophosphate

H₂

imidazole acetol-phosphate

L-histidinol phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

H₂O

carbon monoxide

CO₂

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

ammonia

enol-phenylpyruvate

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

L-homocysteine

ethylphosphate

N₂

cobalt-factor III

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-5B

cobalt-precorrin-6A

cob(II)yrinate c-monoamide

cobyrinate

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

cobalt-sirohydrochlorin

cobalt-precorrin-2

cobalt-precorrin-3

cob(II)yrinate a,c-diamide

Mg-protoporphyrin

adenosyl-cobinamide phosphate

adenosylcobinamide-GDP

cobalt-precorrin-4

cobalt-precorrin-5A

protoporphyrin IX

uroporphyrinogen-I

coproporphyrinogen I

protoporphyrinogen IX

uroporphyrinogen-III

oxygen

2-iminosuccinate

2-chloroacetate

(R)-glycerate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(S)-citramalate

preQ₀

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

ammonium

H⁺

Co²⁺

Mg²⁺

Mo²⁺

Zn²⁺

sulfite

selenate

hydrogencarbonate

selenide

nitrate

sulfate

phosphonate

phosphate

triphosphate

diphosphate

chloride

glycine betaine

agmatine

putrescine

dehydrospermidine

spermidine

tyramine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

sulfoacetaldehyde

L-cysteate

3-sulfopyruvate

coenzyme M

(2R)-3-sulfolactate

(2R)-phospho-3-sulfolactate

3'-dephospho-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

2-methylacetoacetyl-CoA

acetyl-CoA

isobutanoyl-CoA

succinyl-CoA

propanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

methane

riboflavin

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5,10-methenyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

5-formyl-tetrahydromethanopterin

pyridoxal 5'-phosphate

FMN

FAD

(R)-NADHX

(S)-NADHX

NADPH

NADH

NADP⁺

NAD⁺

caldariellaquinone

caldariellaquinol

hypoxanthine

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

adenylo-succinate

5'-deoxyadenosine

dADP

dATP

IDP

ITP

dIDP

dITP

dGDP

dGTP

GDP

GTP

GMP

IMP

XMP

ADP

ATP

AMP

adenosine

2'-deoxyuridine

2'-deoxycytidine

thymidine

dTTP

dCTP

dUTP

UTP

CTP

dUMP

dTMP

dCMP

CMP

UMP

dTDP

dUDP

dCDP

CDP

UDP

β-nicotinamide D-ribonucleotide

GDP-α-D-mannose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

uracil

thymine

adenine

UDP-α-D-glucose

CDP-α-D-glucose

dTDP-α-D-glucose

UDP-α-D-galactose

UDP-α-D-glucuronate

UDP-N-acetyl-α-D-glucosamine

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

CDP-α-abequose

CDP-4-dehydro-3,6-dideoxy-α-D-glucose

molybdopterin

5-methyl-tetrahydrosarcinapterin

tetrahydrosarcinapterin

methyl-CoM

coenzyme A

oxidized coenzyme F₄₂₀-0

oxidized coenzyme F₄₂₀-2

precorrin-7

precorrin-8x

precorrin-6B

precorrin-6A

precorrin-5

precorrin-4

precorrin-3B

precorrin-3A

precorrin-1

precorrin-2

sirohydrochlorin

6,7-dimethyl-8-(1-D-ribityl)lumazine

molybdopterin adenine dinucleotide

7,8-dihydroneopterin 3'-triphosphate

6-carboxy-5,6,7,8-tetrahydropterin

orotate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

diacetyl

acetaldehyde

formaldehyde

(S)-lactaldehyde

D-glyceraldehyde

α-D-ribofuranose

ethanol

N-acetyl-α-D-glucosamine 1-phosphate

D-ribulose-1,5-bisphosphate

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

α-D-ribose 5-phosphate

β-D-ribose 5-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

chorismate

L-aspartate

succinate

fumarate

(S)-malate

(R)-malate

(2R)-homocitrate

cis-homoaconitate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

pyruvate

2-oxobutanoate

2-oxoglutarate

acetate

formate

propanoate

(S)-lactate

carbamate

L-α-amino-ε-keto-pimelate

L-serine

glycine

L-tyrosine

L-glutamine

L-threonine

L-cysteine

L-lysine

L-histidine

L-arginine

L-glutamate

L-isoleucine

L-alanine

L-valine

L-methionine

L-tryptophan

L-leucine

L-phenylalanine

creatine

(R)-β-lysine

L,L-diaminopimelate

L-aspartyl-4-phosphate

L-ornithine

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

3-phospho-L-serine

N-acetyl-L-glutamate

L-citrulline

L-canaline

L-homoserine

L-aspartate 4-semialdehyde

O-phospho-L-homoserine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

meso-diaminopimelate