an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

CO₂

H₂O

carboxyphosphate

carbamoyl phosphate

D-gluconate 6-phosphate

anthranilate

oxalosuccinate

oxaloacetate

adenosine 5'-phosphosulfate

adenosine 5'-phosphoselenate

glycerone phosphate

dihydroxyacetone

γ-L-glutamyl 5-phosphate

5-aminolevulinate

(S)-4-amino-5-oxopentanoate

phosphoenolpyruvate

hydrogen peroxide

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

2-oxovalerate

3-ethylmalate

4-methyl-2-oxopentanoate

(2S)-2-isopropyl-3-oxosuccinate

(2R,3S)-3-isopropylmalate

L-canavanine

canavaninosuccinate

L-arginino-succinate

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

(2S)-2-isopropylmalate

3-methyl-2-oxobutanoate

succinate semialdehyde

4-aminobutanoate

3-oxopropanoate

(S)-3-methyl-2-oxopentanoate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

citrate

3'-phosphoadenylyl-sulfate

H₂

quinolinate

β-nicotinate D-ribonucleotide

(E)-4-coumaroyl-CoA

3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA

2,3-didehydroadipyl-CoA

L-histidinol phosphate

imidazole acetol-phosphate

N-(5-phosphoribosyl)-anthranilate

5-(methylsulfanyl)-ribulose 1-phosphate

S-methyl-5-thio-α-D-ribose 1-phosphate

dihydromethanophenazine

methanophenazine

5-phospho-α-D-ribose 1,2-cyclic phosphate

α-D-ribose-1-methylphosphonate 5-phosphate

selenophosphate

CoB-CoM heterodisulfide

coenzyme B

acetoacetate

4-fumaryl-acetoacetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

coproporphyrinogen III

dihydrolipoate

5-aminopentanoate

4'-phosphopantetheine

hydroxylamine

7-carboxy-7-deazaguanine

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

prenyl diphosphate

4-prenylphlorisobutyrophenone

isopentenyl diphosphate

N¹-(5-phospho-β-D-ribosyl)glycinamide

5-phospho-β-D-ribosylamine

3-ureidopropanoate

glycolate

(R)-4'-phosphopantothenoyl-L-cysteine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-C-methyl-D-erythritol 4-phosphate

DNA without lesion

hydrogenobyrinate a,c-diamide

hydrogenobyrinate

mercuriphenyl acetate

4-maleyl-acetoacetate

nicotinate adenine dinucleotide

α-ribazole 5'-phosphate

5,6-dimethylbenzimidazole

orotidine 5'-phosphate

3-dehydroshikimate

3-dehydroquinate

5-amino-6-(D-ribitylamino)uracil

1-deoxy-L-glycero-tetrulose 4-phosphate

3-deoxy-α-D-manno-2-octulosonate

(indol-3 yl)acetyl-CoA

(indol-3-yl)pyruvate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

glutathioselenol

selenodiglutathione

O-ureido-L-homoserine

β-D-ribosylnicotinate

lipid IV_A

lipid A disaccharide (E. coli)

lipid X

UDP-4-deoxy-4-formamido-β-L-arabinopyranose

porphobilinogen

4-methyl-3-oxoadipate

2-dehydropantoate

1-piperideine 6-carboxylate

1,2-dihydro-β-NADP

pyruvic oxime

enol-phenylpyruvate

ammonia

1-pyrroline

bisorganyltrisulfane

2-isopropylmaleate

3-hydroxypropanoate

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

prephenate

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

norspermidine

carboxynorspermidine

(S)-2-amino-6-oxohexanoate

3-phosphooxypyruvate

histidinol

histidinal

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

thiamine phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

(R)-4'-phosphopantothenate

(R)-pantothenate

L-β-lysine

S-Inosyl-L-homocysteine

xanthine

(S)-dihydroorotate

D-erythro-imidazole-glycerol-phosphate

shikimate

O-acetyl-L-serine

3-deoxy-D-manno-octulosonate 8-phosphate

carbon monoxide

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

hop-22(29)-ene

squalene

urea

hydrogen selenide

glutathione disulfide

thiamine diphosphate

homogentisate

preuroporphyrinogen

4-deoxy-4-formamido-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate

4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate

γ-L-glutamyl-L-cysteine

D-alanyl-D-alanine

carbamate

L-citrulline

L-methionine

glycine

L-alanine

L-glutamate

L-glutamine

L-aspartate

L-phenylalanine

L-serine

L-tryptophan

L-arginine

L-lysine

L-isoleucine

L-threonine

L-leucine

L-valine

L-histidine

L-proline

L-tyrosine

L-cysteine

L-glutamate-5-semialdehyde

L-aspartate 4-semialdehyde

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

L-homoserine

L-homocysteine

L-ornithine

O-phospho-L-homoserine

L-canaline

meso-diaminopimelate

L-aspartyl-4-phosphate

L-saccharopine

O-acetyl-L-homoserine

trans-4-hydroxy-L-proline

N-carbamoylglycine

N-acetyl-L-ornithine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

3-phospho-L-serine

L,L-diaminopimelate

D-alanine

D-proline

D-glutamate

β-alanine

(R)-β-lysine

(R)-3-amino-2-methylpropanoate

protocatechuate

acetate

orotate

(R)-pantoate

5-chloro-5-deoxy-D-ribonate

(S)-1-pyrroline-5-carboxylate

pristanate

palmitate

stearate

octanoate

laurate

7-hydroxylaurate

decanoate

butanoate

18-hydroxyoleate

16-hydroxypalmitate

18-hydroxystearate

(15Z)-tetracosenoate

oleate

phytenate

linoleate

α-linolenate

(R)-lactate

(R)-3-hydroxybutanoate

pyruvate

formate

propanoate

2-oxoglutarate

2-oxobutanoate

5-chloro-4-hydroxy-2-oxopentanoate

glyoxylate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

3-oxoadipate

cis-aconitate

3-carboxy-cis,cis-muconate

D-threo-isocitrate

3-(carbamoylamino)-2-methylpropanoate

chorismate

α,ω-9Z-octadecenedioate

fumarate

succinate

(S)-malate

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

phlorisovalerophenone

4'-α-L-Ara4N-α-Kdo-(2→4)-α-Kdo-(2→6)-[P4'-α-L-ara4N]-lipid A

α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid A

trans,octacis-decaprenyl phosphate

(2E,6E)-farnesyl diphosphate

mono-trans,octa-cis-decaprenyl diphosphate

geranyl diphosphate

4-prenylphlorisovalerophenone

deoxycohumulone

deoxyhumulone

3-octaprenyl-4-hydroxybenzoate

di-trans,octa-cis-undecaprenyl phosphate

di-trans,octa-cis-undecaprenyl diphosphate

geranylgeranyl diphosphate

all-trans-octaprenyl diphosphate

1-(β-D ribofuranosyl)nicotinamide

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

CDP-4-dehydro-6-deoxy-α-D-glucose

ADP-α-D-glucose

GDP-4-dehydro-α-D-rhamnose

GDP-α-D-mannose

GDP-α-D-glucose

CDP-α-D-glucose

dTDP-α-D-glucose

dTDP-4-dehydro-β-L-rhamnose

dTDP-β-L-rhamnose

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-glucosamine 3'-phosphate

UDP-α-D-glucose

UDP-4-amino-4-deoxy-β-L-arabinopyranose

UDP-β-L-threo-pentapyranos-4-ulose

UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine

UDP-α-D-galactose

UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine

UDP-α-D-glucuronate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

CMP-3-deoxy-β-D-manno-octulosonate

D-erythrose 4-phosphate

D-sedoheptulose 7-phosphate

5-phospho-α-D-ribose 1-diphosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

α-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 6-phosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

α-D-glucose 6-phosphate

5-fluoro-5-deoxy-D-ribose 1-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

1-deoxy-D-xylulose 5-phosphate

D-xylulose 5-phosphate

aldehydo-D-arabinose 5-phosphate

D-arabinofuranose 5-phosphate

D-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

α,α-trehalose 6-phosphate

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

a peptidoglycan dimer (E. faecium, tetrapeptide)

a peptidoglycan dimer (E. faeciums)

a peptidoglycan dimer (S. aureus)

a peptidoglycan dimer (mycobacteria)

decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide)

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-(glycyl)₅-D-alanyl-D-alanine

β-D-fructofuranose

β-D-glucopyranose

α-D-glucopyranose

D-glyceraldehyde

keto-D-fructose

D-xylulose

glycerol

α,α-trehalose

maltotetraose

maltohexaose

maltoheptaose

maltotriose

maltopentaose

ethanol

butan-1-ol

methylglyoxal

acetaldehyde

butan-1-al

menadione

caldariellaquinone

diacetyl

acetone

benzene

4-hydroxybenzoate

urate

menadiol

2-methoxy-6-all trans-octaprenyl-1,4-benzoquinol

6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol

caldariellaquinol

3-demethylubiquinol-8

ubiquinol-8

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

adenine

guanine

AMP

GMP

XMP

IMP

ATP

GTP

ITP

ADP

GDP

IDP

dGDP

dIDP

dADP

dGTP

dITP

dATP

hypoxanthine

adenosine

inosine

guanosine

xanthosine

2'-deoxyguanosine

2'-deoxyinosine

2'-deoxyadenosine

6-carboxy-5,6,7,8-tetrahydropterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

5-methyl-tetrahydrosarcinapterin

tetrahydrosarcinapterin

tetrahydromethanopterin

7,8-dihydroneopterin 3'-triphosphate

5,10-methylene-tetrahydromethanopterin

thio-molybdenum cofactor

MoO₂-molybdopterin cofactor

reduced riboflavin

FMNH₂

riboflavin

FMN

6,7-dimethyl-8-(1-D-ribityl)lumazine

thymine

uracil

preQ₁

isoguanine

dUTP

dUDP

CTP

CDP

dCTP

dCDP

UTP

UDP

dTTP

dTDP

5,6-dihydrothymine

5,6-dihydrouracil

dUMP

dTMP

UMP

CMP

uridine

cytidine

2'-deoxyuridine

2'-deoxycytidine

hydantoin

adenosylcobalamin

cob(I)alamin

sirohydrochlorin

cobyrinate

cobalt-precorrin-2

precorrin-2

precorrin-8x

precorrin-3A

cobalt-precorrin-5A

cobalt-precorrin-4

precorrin-1

coenzyme A

coenzyme M

(R)-lipoate

adenylo-succinate

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

8-oxo-GTP

8-oxo-dGTP

ppGpp

pppGpp

5-chloro-5-deoxyribose 1-phosphate

5'-chloro-5'-deoxyadenosine

β-nicotinamide D-ribonucleotide

5-hydroxy-CTP

2-hydroxy-dATP

cyclic di-3',5'-guanylate

NADP⁺

NAD⁺

NADPH

NADH

5'-deoxy-5'-fluoroadenosine

(S)-NADHX

(R)-NADHX

nicotinate

pyridoxal 5'-phosphate

pyridoxine 5'-phosphate

pyridoxamine 5'-phosphate

phenylacetate

(25S)-3-oxocholest-4-en-26-oyl-CoA

(25S)-3-oxocholest-4-en-26-oate

methane

succinyl-CoA

acetyl-CoA

2-methylacetoacetyl-CoA

methylacrylyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA

(E)-2-methylcrotonoyl-CoA

3-hydroxyisovaleryl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

(3S)-hydroxyadipyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA

malonyl-CoA

isobutanoyl-CoA

(3S)-citryl-CoA

(2R)-ethylmalonyl-CoA

(2S)-ethylmalonyl-CoA

3'-dephospho-CoA

phenylacetyl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

(E)-glutaconyl-CoA

(R)-2-hydroxyglutaryl-CoA

4-hydroxybenzoyl-CoA

2-methylbutanoyl-CoA

(S)-3-hydroxy-isobutanoyl-CoA

oleoyl-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

4-methyl-3-oxoadipyl-CoA

3-oxoadipyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

16-hydroxypalmitoyl-CoA

palmitoyl-CoA

stearoyl-CoA

18-hydroxyoleoyl-CoA

18-hydroxystearoyl-CoA

pristanoyl-CoA

octanoyl-CoA

lauroyl-CoA

7-hydroxylauroyl-CoA

decanoyl-CoA

propanoyl-CoA

butanoyl-CoA

(2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA

(Z)-15-tetracosenoyl-CoA

(S)-3-hydroxydecanoyl-CoA

(S)-3-hydroxyoctanoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(3S,6Z,9Z,12Z,15Z,18Z)-3-hydroxytetracosapentaenoyl-CoA

(3S,6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoyl-CoA

phytenoyl-CoA

(2E)-oct-2-enoyl-CoA

(2E)-dec-2-enoyl-CoA

(2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA

crotonyl-CoA

(R)-methylmalonyl-CoA

(S)-methylmalonyl-CoA

glutathione

3-sulfopyruvate

L-cysteate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

methanethiol

S-sulfanylglutathione

agmatine

putrescine

4-aminobutanal

(2Z)-2-aminobut-2-enoate

superoxide

hydroxyl radical

nitrate

molybdate

hydrogencarbonate

selenate

sulfite

nitrite

selenide

OH^-

selenite

sulfate

chloride

phosphonate

phosphate

diphosphate

triphosphate

Fe³⁺

Mg²⁺

Co²⁺

Hg²⁺

Fe²⁺

ammonium

K⁺

H⁺

2-chloroacetate

preQ₀

2-methoxy-6-(all-trans-octaprenyl)phenol

2-octaprenylphenol

3-(all-trans-octaprenyl)benzene-1,2-diol

(2R)-2,3-dihydroxy-3-methylbutanoate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

2-iminosuccinate

2-iminobutanoate

oxygen

hydrogen sulfide

Hg⁰

protoporphyrinogen IX

protoporphyrin IX

uroporphyrinogen-I

uroporphyrinogen-III

protoheme

cobalt-sirohydrochlorin

cob(II)yrinate a,c-diamide

cob(II)yrinate c-monoamide

nitrous oxide

phosphonoacetaldehyde

(2-aminoethyl)phosphonate

ethylphosphate

DNA with lesion