an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

(R)-4'-phosphopantothenate

dimethyl sulfoxide

6-phospho D-glucono-1,5-lactone

glutathione disulfide

N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate

3-ureidoacrylate

aminoacrylate

(Z)-3-ureidoacrylate peracid

(Z)-3-peroxyaminoacrylate

(Z)-2-methylureidoacrylate peracid

(Z)-2-methyl-peroxyaminoacrylate

N⁵-carboxyaminoimidazole ribonucleotide

1,6-anhydro-N-acetyl-β-muramate

N-acetyl-D-muramate 6-phosphate

D-gluconate 6-phosphate

2-dehydro-3-deoxy-D-gluconate 6-phosphate

2-methyl-4-chlorophenol

histidinal

histidinol

L-histidinol phosphate

S-formylglutathione

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

nicotinate adenine dinucleotide

quinolinate

pimeloyl-CoA

8-amino-7-oxononanoate

7,8-diaminopelargonate

carboxyphosphate

prephenate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

(3R)-3-hydroxy-2-oxo-4 phosphooxybutanoate

3-phosphooxypyruvate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

xanthine

(2S)-2-isopropyl-3-oxosuccinate

3-ethylmalate

2-oxovalerate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA

porphobilinogen

preuroporphyrinogen

L-canavanine

4-phosphooxy-L-threonine

(2S)-2-amino-3-oxo-4-phosphooxybutanoate

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

(S)-3-methyl-2-oxopentanoate

4-methyl-2-oxopentanoate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-aceto-2-hydroxybutanoate

palmitaldehyde

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

α-D-glucosamine 1-phosphate

dihydrolipoamide

S-acetyldihydrolipoamide

(S)-5-hydroxyisourate

(S)-2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline

β-nicotinate D-ribonucleotide

5-amino-6-(D-ribitylamino)uracil

thiamine phosphate

thiamine diphosphate

3-oxopropanoate

4-aminobutanoate

succinate semialdehyde

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

S-methyl-5'-thioadenosine

5-(methylsulfanyl)-α-D-ribose

S-ribosyl-L-homocysteine

2-phosphoglycolate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

coproporphyrinogen III

N-(5-phosphoribosyl)-anthranilate

anthranilate

(S)-2-acetolactate

5-guanidino-2-oxopentanoate

adenosine 5'-phosphosulfate

adenosine 5'-phosphoselenate

carbamoyl phosphate

isopentenyl diphosphate

adenosine 3',5'-bisphosphate

N-succinyl-L,L-2,6-diaminopimelate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

coniferaldehyde

3-dehydroquinate

3-dehydroshikimate

5-enolpyruvoyl-shikimate 3-phosphate

orotidine 5'-phosphate

3-deoxy-α-D-manno-2-octulosonate

lipid IV_A

prenyl diphosphate

dethiobiotin

O-acetyl-L-serine

3-amino-1-hydroxyacetone 1-phosphate

DNA without lesion

N-acetyl-L-glutamate 5-semialdehyde

glycerone phosphate

urea

urea-1-carboxylate

6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline 2,4-dicarboxylate

4-amino-4-deoxychorismate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

lipid X

lipid A disaccharide (E. coli)

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

2-C-methyl-D-erythritol 4-phosphate

3-deoxy-D-manno-octulosonate 8-phosphate

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

(S)-2,3,4,5-tetrahydrodipicolinate

N-succinyl-2-amino-6-ketopimelate

7-carboxy-7-deazaguanine

propane-1,3-diamine

CO₂

oxaloacetate

citrate

L-arginino-succinate

O-ureido-L-homoserine

canavaninosuccinate

(S)-dihydroorotate

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

glycolate

methylamine

N-ethylglycine

ethylamine

2-iminoacetate

hydrogen peroxide

N-acetylglutamyl-phosphate

(R)-pantothenate

2-dehydropantoate

γ-L-glutamyl 5-phosphate

3-methyl-2-oxobutanoate

(2S)-2-isopropylmalate

shikimate

shikimate 3-phosphate

1-deoxy-L-glycero-tetrulose 4-phosphate

phosphoenolpyruvate

3-deoxy-D-arabino-heptulosonate 7-phosphate

H₂O

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

ammonia

6-(2-amino-2-carboxylatoethyl)-7-hydroxy-8-oxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate

2-amino-4-[5-(2-amino-2-carboxylatoethyl)-2-hydroxyphenyl]pentanedioate

2-amino-4-[3-(2-amino-2-carboxylatoethyl)-6-oxocyclohexa-1,4-dien-1-yl]pentanedioate

6-(2-amino-2-carboxylatoethyl)-1,2,3,4-tetrahydroquinoline-2,4-dicarboxylate

selenodiglutathione

glutathioselenol

hydrogen selenide

autoinducer 2

1,4-dihydroxy-2-naphthoate

DNA with lesion

L-homocysteine

4-methylphenol

protoheme

protoporphyrinogen IX

protoporphyrin IX

uroporphyrinogen-I

coproporphyrinogen I

uroporphyrinogen-III

siroheme

hydrogen sulfide

oxygen

2-iminosuccinate

2-iminobutanoate

2-chloroacetate

sn-glycerol 3-phosphate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

(2R)-2,3-dihydroxy-3-methylbutanoate

S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine

(S)-methylmalonate-semialdehyde

3-(all-trans-octaprenyl)benzene-1,2-diol

2-octaprenylphenol

2-methoxy-6-(all-trans-octaprenyl)phenol

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

2,4-dichlorophenol

3,5-dichlorocatechol

5-chloro-3-methylcatechol

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

caldariellaquinol

ubiquinol-8

menaquinol-8

menaquinol-6

menaquinol-7

demethylmenaquinol-8

demethylmenaquinol-6

demethylmenaquinol-7

3-demethylubiquinol-8

caldariellaquinone

NADPH

NADH

NADP⁺

NAD⁺

glycine betaine

superoxide

hydroxyl radical

(2E,6E)-farnesyl diphosphate

Fe³⁺

K⁺

H⁺

ammonium

Mg²⁺

Fe²⁺

sulfite

nitrite

selenate

hydrogencarbonate

sulfate

hydrogensulfite

selenite

OH^-

phosphate

triphosphate

diphosphate

chloride

dimethyl sulfide

S-(hydroxymethyl)glutathione

glutathione

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

methanesulfinate

dimethyl sulfone

methanesulfonate

(R)-S-lactoylglutathione

betaine aldehyde

(2Z)-2-aminobut-2-enoate

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

L-alanyl-γ-D-glutamyl-meso-diaminopimelate

D-alanyl-D-alanine

γ-L-glutamyl-L-cysteine

3-hexaprenyl-4-hydroxybenzoate

4-hydroxybenzoate

menadiol

6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol

2-methoxy-6-all trans-octaprenyl-1,4-benzoquinol

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

ferulate

4-aminobenzoate

preQ₀

coenzyme A

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

7,8-dihydrofolate monoglutamate

5,10-methylene-tetrahydromethanopterin

tetrahydromethanopterin

thiamine

riboflavin

nicotinate

pyridoxamine 5'-phosphate

pyridoxal 5'-phosphate

pyridoxine 5'-phosphate

menadione

3-oxo-4-pregnene-20-carboxyl-CoA

3,22-dioxochol-4-en-24-oyl-CoA

3'-dephospho-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-butanoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxohexanoyl)-CoA

4-hydroxybenzoyl-CoA

(5E)-3-oxo-dodec-5-enoyl-CoA

(3E)-dec-3-enoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-hexanoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxooctanoyl)-CoA

6-cis, 3-oxo-tridecenoyl-CoA

4-cis-undecenoyl-CoA

4-trans-3-oxo-undecenoyl-CoA

2-trans-nonenoyl-CoA

5-cis, 7-trans-3-oxo-tetradecadienoyl-CoA

(3Z,5E)-dodeca-3,5-dienoyl-CoA

(+)-7-epi-jasmonoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxobutanoyl)-CoA

6-trans-3-oxo-tridecenoyl-CoA

4-trans-undecenoyl-CoA

succinyl-CoA

malonyl-CoA

acetyl-CoA

(3Z)-dodec-3-enoyl-CoA

oleoyl-CoA

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

propanoyl-CoA

butanoyl-CoA

decanoyl-CoA

octanoyl-CoA

hexanoyl-CoA

lauroyl-CoA

palmitoyl-CoA

stearoyl-CoA

myristoyl-CoA

(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA

(6Z,9Z,12Z,15Z,18Z,21Z)-3-oxotetracosahexaenoyl-CoA

(6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoyl-CoA

3-oxododecanoyl-CoA

3-oxodecanoyl-CoA

3-oxooctanoyl-CoA

3-oxohexanoyl-CoA

3-oxo-(5Z)-tetradecenoyl-CoA

3-oxo-myristoyl-CoA

3-oxo-palmitoyl-CoA

(S)-(+)-allantoin

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-4-imidazolecarboxyamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

chorismate

succinate

fumarate

L-aspartate

(S)-malate

(2R,3S)-2-methylisocitrate

cis-2-methylaconitate

cis-aconitate

D-threo-isocitrate

pyruvate

acetate

formate

(R)-lactate

laurate

stearate

palmitate

orotate

(R)-pantoate

(S)-1-pyrroline-5-carboxylate

carbamate

L-α-amino-ε-keto-pimelate

L-serine

β-alanine

L-leucine

L-alanine

L-glutamine

glycine

L-proline

D-glutamate

L-glutamate

L-arginine

L-histidine

L-lysine

L-tyrosine

L-tryptophan

D-arginine

D-alanine

L-aspartyl-4-phosphate

iminoarginine

3-phospho-L-serine

sarcosine

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

N-acetyl-L-citrulline

N-acetyl-L-methionine

N-acetyl-L-glutamate

trans-4-hydroxy-L-proline

O-acetyl-L-homoserine

L-isoleucine

L,L-diaminopimelate

L-ornithine

L-2,4-diaminobutanoate

L-valine

L-threonine

L-methionine

L-cysteine

L-citrulline

O-phospho-L-homoserine

L-canaline

O-succinyl-L-homoserine

L-aspartate 4-semialdehyde

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

L-homoserine

L-glutamate-5-semialdehyde

meso-diaminopimelate

S-(4-hydroxy-nonenal-3-yl)-L-cysteine

2-oxobutanoate

glyoxylate

2-oxoglutarate

ethanol

methanol

myo-inositol

1D-myo-inositol 1-monophosphate

1D-myo-inositol 3-monophosphate

trans,octacis-decaprenyl phosphate

di-trans,octa-cis-undecaprenyl phosphate

all-trans-octaprenyl diphosphate

all-trans-nonaprenyl diphosphate

all-trans-hexaprenyl diphosphate

all-trans-decaprenyl diphosphate

all-trans-heptaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

3-octaprenyl-4-hydroxybenzoate

3-nonaprenyl-4-hydroxybenzoate

3-decaprenyl-4-hydroxybenzoate

3-heptaprenyl-4-hydroxybenzoate

1-oleoyl-sn-glycerol 3-phosphate

6_G-kestotriose

1,1-kestotetraose

1-kestotriose

sucrose

aldehydo-D-ribose

α-D-ribofuranose

β-D-ribofuranose

N-acetyl-α-D-glucosamine 1-phosphate

N-acetyl-β-D-glucosamine

D-glyceraldehyde

glycolaldehyde

α-D-galactopyranose

β-D-galactopyranose

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide)

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

CMP-3-deoxy-β-D-manno-octulosonate

UDP-α-D-glucose

UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

UDP-α-D-galactose

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine

UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-glucosamine

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-sedoheptulose 7-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-erythrose 4-phosphate

4-phospho-D-erythronate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-arabinofuranose 5-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

α-D-ribose 5-phosphate

β-D-ribose 5-phosphate

α-D-ribose-1-phosphate

β-D-fructofuranose 1-phosphate

diacetyl

methylglyoxal

pyrroloquinoline quinone

(R)-acetoin

formaldehyde

acetaldehyde

precorrin-2

precorrin-1

sirohydrochlorin

dTTP

dCTP

dCMP

dTDP

dCDP

dUDP

dUTP

uracil

CTP

CDP

UTP

dUMP

dTMP

UDP

CMP

UMP

guanine

hypoxanthine

adenine

isoguanine

preQ₁

guanosine

adenosine

inosine

xanthosine

2'-deoxyadenosine

2'-deoxyinosine

ITP

GTP

ATP

IDP

GDP

ADP

GMP

XMP

IMP

AMP

dATP

dGTP

dITP

dIDP

dGDP

dADP

7,8-dihydrolumazine

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

7,8-dihydropterin

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydroneopterin

7,8-dihydromonapterin

6-(hydroxymethyl)-7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

7,8-dihydroneopterin 3'-phosphate

7,8-dihydropteroate

6-carboxy-5,6,7,8-tetrahydropterin

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

adenylo-succinate

5'-deoxyadenosine

8-oxo-GTP

8-oxo-dGTP

P¹,P⁴-bis(5'-adenosyl) tetraphosphate

5-hydroxy-CTP

2-hydroxy-dATP

β-nicotinamide D-ribonucleotide

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA