an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

α-D-ribose-1-methylphosphonate 5-phosphate

5-phospho-α-D-ribose 1,2-cyclic phosphate

hydrogen peroxide

(S)-dihydroorotate

DNA without lesion

propan-2-ol

5-oxo-L-proline

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

dihydroxyacetone

D-erythro-imidazole-glycerol-phosphate

N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

tartronate semialdehyde

1,4-dihydroxy-2-naphthoyl-CoA

2-succinylbenzoate

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

α-D-glucosamine 1-phosphate

hydroxyatrazine

N-isopropylammelide

ethylamine

β-nicotinate D-ribonucleotide

quinolinate

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

3-deoxy-D-arabino-heptulosonate 7-phosphate

(2S)-2-isopropylmalate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

citrate

5-phospho-β-D-ribosylamine

3-methyl-2-oxobutanoate

oxaloacetate

CO₂

acetyl phosphate

S-adenosyl 3-(methylsulfanyl)propylamine

ethanolamine

1-pyrroline

anthranilate

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

5-deoxy-α-ribose 1-phosphate

S-methyl-5'-thioadenosine

S-methyl-5-thio-α-D-ribose 1-phosphate

butanoyl phosphate

imidazole acetol-phosphate

L-histidinol phosphate

glycolate

hydroxypyruvate

carbamoyl phosphate

carboxyphosphate

phosphoenolpyruvate

H₂O

glycerone phosphate

ammonia

enol-phenylpyruvate

1,2-dihydro-β-NADP

4-oxoglutaramate

orotidine 5'-phosphate

thiamine diphosphate

(4-hydroxyphenyl)acetate

formamide

(R)-4'-phosphopantothenate

shikimate

2-amino-3-carboxymuconate-6-semialdehyde

4-aminobutanoate

glutathione disulfide

1,4-dihydroxy-2-naphthoate

1,3-propanediol

3-ureidopropanoate

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

O-ureido-L-homoserine

3-hydroxypropanal

N-acetyl-α-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol

ManNAc-GlcNAc-PP-undecaprenol

histidinal

oxalosuccinate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

phosphocholine

5-dehydro-4-deoxy-D-glucarate

(2S,3S)-2,3-dihydroxy-5-oxohexanedioate

2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate

adenosine 5'-phosphosulfate

(3S,5S)-3,5-diaminohexanoate

(S)-5-amino-3-oxohexanoate

acetoacetate

3-hydroxy-5-oxohexanoate

3-hydroxy-5- oxohexanoyl-CoA

L-quinate

creatinine

3-dehydroquinate

3-dehydroshikimate

prephenate

2-dehydro-3-deoxy-D-gluconate

2-dehydro-3-deoxy-D-gluconate 6-phosphate

N-(5-phosphoribosyl)-anthranilate

histidinol

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

isochorismate

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

L-arginino-succinate

canavaninosuccinate

L-canavanine

(2Z,4E)-2-hydroxyhexa-2,4-dienedioate

aminoacetone

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate

5,6-dimethylbenzimidazole

α-ribazole 5'-phosphate

hypotaurine

2-iminoacetate

O-acetyl-L-serine

xanthine

2-dehydropantoate

(R)-pantothenate

selenophosphate

H₂

N⁵-carboxyaminoimidazole ribonucleotide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

urea

7-carboxy-7-deazaguanine

4-imidazolone-5-propanoate

urocanate

isopentenyl diphosphate

preuroporphyrinogen

coproporphyrinogen III

porphobilinogen

carbon monoxide

(indol-3-yl)pyruvate

β-D-ribosylnicotinate

(S)-2,3-dihydrodipicolinate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

2-C-methyl-D-erythritol 4-phosphate

deethylsimazine

N-ethylammeline

5-(methylsulfanyl)-ribulose 1-phosphate

propanoyl phosphate

1-deoxy-L-glycero-tetrulose 4-phosphate

5-amino-6-(D-ribitylamino)uracil

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

coenzyme B

methanophenazine

CoB-CoM heterodisulfide

dihydromethanophenazine

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

nicotinate adenine dinucleotide

thiamine phosphate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

dimethylamine

L-β-lysine

DNA with lesion

L-homocysteine

4-methylphenol

phenylacetate

ethylphosphate

N₂

adenosylcobalamin

cob(I)alamin

cobalt-precorrin-4

cobalt-precorrin-5A

cobalt-precorrin-5B

cobalt-precorrin-6A

Mg-protoporphyrin

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

cobyrinate

protoheme

uroporphyrinogen-I

coproporphyrinogen I

uroporphyrinogen-III

protoporphyrinogen IX

protoporphyrin IX

oxygen

hydrogen sulfide

2-iminobutanoate

2-iminosuccinate

2-iminopropanoate

2-chloroacetate

sn-glycerol 3-phosphate

(R)-glycerate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

(2R)-2,3-dihydroxy-3-methylbutanoate

α-D-glucosamine 6-phosphate

3-(all-trans-octaprenyl)benzene-1,2-diol

2-octaprenylphenol

(indole-3-yl)acetonitrile

preQ₀

5'-deoxy-5'-fluoroadenosine

5-fluoro-5-deoxy-D-ribose 1-phosphate

5'-chloro-5'-deoxyadenosine

5-chloro-5-deoxyribose 1-phosphate

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

Fe³⁺

H⁺

ammonium

Mn²⁺

Co²⁺

Fe²⁺

Mg²⁺

hydrogencarbonate

molybdate

sulfate

hydrogensulfite

OH^-

selenide

selenite

selenate

superoxide

sulfite

phosphonate

phosphate

diphosphate

triphosphate

chloride

hydroxyl radical

(2E,6E)-farnesyl diphosphate

glycine betaine

choline

(2Z)-2-aminobut-2-enoate

2-aminoprop-2-enoate

agmatine

4-aminobutanal

spermidine

putrescine

methanethiol

glutathione

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

L-cysteate

3-sulfopyruvate

taurine

2-sulfinoacetaldehyde

coenzyme M

sulfoacetaldehyde

(2R)-phospho-3-sulfolactate

2-methylacetoacetyl-CoA

succinyl-CoA

isobutanoyl-CoA

acetyl-CoA

malonyl-CoA

(S)-3-aminobutanoyl-CoA

phenylacetyl-CoA

3'-dephospho-CoA

(2S)-ethylmalonyl-CoA

(2R)-ethylmalonyl-CoA

(R)-2-hydroxyglutaryl-CoA

(E)-glutaconyl-CoA

(R)-methylmalonyl-CoA

(S)-methylmalonyl-CoA

crotonyl-CoA

oleoyl-CoA

18-hydroxyoleoyl-CoA

(S)-3-hydroxybutanoyl-CoA

propanoyl-CoA

pentanoyl-CoA

butanoyl-CoA

hexadecanedioyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

ethene

methane

(indol-3-yl)acetate

nicotinate

riboflavin

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

7,8-dihydrofolate monoglutamate

5,10-methylene-tetrahydromethanopterin

tetrahydromethanopterin

pyridoxamine 5'-phosphate

pyridoxine 5'-phosphate

pyridoxal 5'-phosphate

menadione

FMNH₂

FMN

(R)-NADHX

(S)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

caldariellaquinone

caldariellaquinol

hypoxanthine

GMP

IDP

ITP

dIDP

dITP

dATP

dGTP

GTP

dADP

dGDP

GDP

IMP

XMP

5'-deoxyadenosine

AMP

ATP

ADP

isoguanine

8-oxo-dGTP

8-oxo-GTP

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

2'-deoxyadenosine

2'-deoxyinosine

adenylo-succinate

pppGpp

ppGpp

2'-deoxyguanosine

(5R)-5,6-dihydro-5-(thymidin-7-yl)thymidine (in DNA)

two adjacent thymidines in DNA

xanthosine

guanosine

inosine

adenosine

cytidine

uridine

thymidine

2'-deoxycytidine

2'-deoxyuridine

cyclic di-3',5'-guanylate

2-hydroxy-dATP

5-hydroxy-CTP

dTTP

dCTP

dUTP

CTP

UTP

dCMP

dTMP

dUMP

UMP

CMP

dTDP

dUDP

dCDP

CDP

UDP

β-nicotinamide D-ribonucleotide

ADP-α-D-glucose

preQ₁

thymine

uracil

guanine

adenine

CDP-choline

5,6-dihydrouracil

5,6-dihydrothymine

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-α-D-glucuronate

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-mannosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-glucosamine

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

coenzyme A

tetrahydrosarcinapterin

5-methyl-tetrahydrosarcinapterin

(S)-1-pyrroline-5-carboxylate

precorrin-1

precorrin-6B

precorrin-6A

precorrin-8x

precorrin-2

precorrin-3A

hydantoin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydropteroate

6-carboxy-5,6,7,8-tetrahydropterin

orotate

dipicolinate

urate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

2,3-dihydroxybenzoate

protocatechuate

menadiol

6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol

all trans-decaprenyl-2-methoxy-6-1,4-benzoquinol

4-aminobenzoate

diacetyl

acetone

methylglyoxal

acetaldehyde

formaldehyde

1-propanal

α-D-xylopyranose

α-D-glucopyranose

β-D-glucopyranose

propan-1-ol

ethanol

glycerol

(S)-propane-1,2-diol

1-(β-D ribofuranosyl)nicotinamide

aldehydo-D-galacturonate

maltotriose

isoprimeverose

maltotetraose

maltoheptaose

maltohexaose

maltopentaose

N-acetyl-α-D-glucosamine 1-phosphate

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

β-D-fructose 1,6-bisphosphate

D-tagatofuranose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-glucopyranose 1-phosphate

D-altronate

D-mannonate

1-C16:0-α,ω-dicarboxyl-2-lysophosphatidate

1-(18-hydroxyoleoyl)-sn-glycrol 3-phosphate

1-oleoyl-sn-glycerol 3-phosphate

trans,octacis-decaprenyl phosphate

di-trans,octa-cis-undecaprenyl phosphate

geranylgeranyl diphosphate

all-trans-heptaprenyl diphosphate

3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine

3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine

(2R,3R)-3-methylornithinyl-N⁶-lysine

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

chorismate

(3E)-2-oxohex-3-enedioate

L-aspartate

succinate

fumarate

(S)-malate

D-glucarate

D-galactarate

3-(carbamoylamino)-2-methylpropanoate

cis-aconitate

D-threo-isocitrate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

pyruvate

2-oxobutanoate

2-oxoglutarate

glyoxylate

4-(methylsulfanyl)-2-oxobutanoate

acetate

formate

propanoate

butanoate

pentanoate

(R)-pantoate

D-tagaturonate

carbamate

L-serine

L-threonine

glycine

L-glutamine

L-cysteine

L-tyrosine

L-arginine

L-histidine

L-lysine

L-glutamate

L-tryptophan

L-phenylalanine

L-isoleucine

L-alanine

L-leucine

L-methionine

L-proline

L-valine

creatine

N-carbamoylsarcosine

β-alanine

β-glutamate

(R)-β-lysine

(R)-3-amino-2-methylpropanoate

D-glutamate

(3R)-3-methyl-D-ornithine

D-proline

D-alanine

L-ornithine

L-isoglutamine

L-cystathionine

L,L-diaminopimelate

L-aspartyl-4-phosphate

N-carbamoyl-L-aspartate

N⁶,N⁶-dimethyl-L-arginine

formyl-L-isoglutamine

N-formimino-L-glutamate

N-acetyl-L-ornithine

D-nopaline

L-2-amino-3-oxobutanoate

sarcosine

N-carbamoylglycine

N-acetyl-L-glutamate

trans-4-hydroxy-L-proline

O-acetyl-L-homoserine

L-citrulline

S-adenosyl-L-homocysteine

O-phospho-L-homoserine

L-aspartate 4-semialdehyde

S-adenosyl-L-methionine

L-glutamate-5-semialdehyde

L-canaline

L-pyrrolysine

L-homoserine

O-succinyl-L-homoserine

hypoglycin A

meso-diaminopimelate

hypoglycin B

L-cysteinylglycine

D-alanyl-D-alanine