an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

ammonia

enol-phenylpyruvate

1,2-dihydro-β-NADP

S-methyl-5'-thioadenosine

(S)-dihydroorotate

(R)-mevalonate diphosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

acetyl phosphate

L-histidinol phosphate

prephenate

preuroporphyrinogen

all-trans-13,14-dihydroretinol

porphobilinogen

(indol-3 yl)acetyl-CoA

(indol-3-yl)pyruvate

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

3-phosphooxypyruvate

5-oxo-L-proline

coenzyme B

CoB-CoM heterodisulfide

histidinal

histidinol

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

oxalosuccinate

3-hydroxypropanoate

N-acetyl-L-glutamate 5-semialdehyde

N-(5-phosphoribosyl)-anthranilate

anthranilate

deethylsimazine

N-ethylammeline

H₂

methanophenazine

dihydromethanophenazine

1-deoxy-L-glycero-tetrulose 4-phosphate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

hydrogen peroxide

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

(2Z,4Z)-2-hydroxyhepta-2,4-dienedioate

(4Z)-2-oxohept-4-enedioate

5,6-dimethylbenzimidazole

α-ribazole 5'-phosphate

isopentenyl diphosphate

prenyl diphosphate

(R)-5-phosphomevalonate

N¹-(5-phospho-β-D-ribosyl)glycinamide

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

N⁵-carboxyaminoimidazole ribonucleotide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

Coα-[α-(5-hydroxybenzimidazolyl)]-Coβ-methylcobamide

orotidine 5'-phosphate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

quinolinate

oxalate

coproporphyrinogen III

hexulose 6-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

4'-phosphopantetheine

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

(R)-mevalonate

7,8-didemethyl-8-hydroxy-5-deazariboflavin

(2S)-lactyl-2-diphospho-5'-guanosine

nicotinate adenine dinucleotide

2-keto-D-gluconate

2,5-didehydro-D-gluconate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

5-phospho-β-D-ribosylamine

β-nicotinate D-ribonucleotide

carbon monoxide

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

citrate

(2S)-2-isopropylmalate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

S-adenosyl 3-(methylsulfanyl)propylamine

N-acetylglutamyl-phosphate

carboxyphosphate

5-amino-6-(D-ribitylamino)uracil

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

L-arginino-succinate

O-ureido-L-homoserine

canavaninosuccinate

CO₂

glycerone phosphate

oxaloacetate

phosphoenolpyruvate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

carbamoyl phosphate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

3-methyl-2-oxobutanoate

H₂O

nicotinate

riboflavin

all-trans-retinol

N⁵-methyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

tetrahydromethanopterin

5-formyl-tetrahydromethanopterin

pyridoxamine 5'-phosphate

pyridoxine 5'-phosphate

pyridoxal 5'-phosphate

FAD

FMNH₂

FMN

(R)-NADHX

(S)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

5'-deoxyadenosine

dADP

dATP

IDP

ITP

dIDP

dITP

dGDP

dGTP

IMP

adenylo-succinate

GTP

GDP

ADP

ATP

XMP

GMP

AMP

adenosine

cytidine

uridine

2'-deoxycytidine

2'-deoxyuridine

dTTP

dCTP

dUTP

UTP

CTP

dUMP

dTMP

CMP

UMP

dTDP

dCDP

dUDP

UDP

CDP

GDP-α-D-mannose

ADP-α-D-glucose

adenine

UDP-α-D-glucose

dTDP-α-D-glucose

UDP-α-D-galactose

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

5-methyl-tetrahydrosarcinapterin

tetrahydrosarcinapterin

coenzyme M

methyl-CoM

coenzyme A

oxidized coenzyme F₄₂₀-0

orotate

cobalt-precorrin-3

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-4

cobalt-precorrin-5A

cobalt-precorrin-5B

cobalt-precorrin-6A

precorrin-1

precorrin-2

sirohydrochlorin

cobyrinate

Coα-[α-(5-hydroxybenzimidazolyl)]-cobamide

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

tyramine

diacetyl

D-glyceraldehyde

acetaldehyde

formaldehyde

methanol

1D-myo-inositol 3-monophosphate

α-D-glucopyranose 1-phosphate

D-glyceraldehyde 3-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-tagatofuranose 1,6-bisphosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-glucose 6-phosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

acetate

5-chloro-5-deoxy-D-ribonate

carbamate

L-citrulline

L-homocysteine

L-canaline

L-homoserine

L-aspartate 4-semialdehyde

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

O-phospho-L-homoserine

L-ornithine

meso-diaminopimelate

L-lysine

L-valine

L-isoleucine

L-leucine

L-arginine

L-methionine

L-histidine

glycine

L-phenylalanine

L-tyrosine

L-serine

L-tryptophan

L-threonine

L-aspartate

L-glutamine

L-glutamate

(3R)-3-methyl-D-ornithine

L-aspartyl-4-phosphate

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

3-phospho-L-serine

N-acetyl-L-glutamate

chorismate

fumarate

(S)-malate

cis-aconitate

D-threo-isocitrate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

pyruvate

4-(methylsulfanyl)-2-oxobutanoate

5-chloro-4-hydroxy-2-oxopentanoate

2-oxoglutarate

2-oxobutanoate

formate

(S)-lactate

phenylacetate

cobalt-factor III

cobalt-sirohydrochlorin

Mg-protoporphyrin

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

uroporphyrinogen-I

protoporphyrin IX

protoporphyrinogen IX

uroporphyrinogen-III

oxygen

2-iminosuccinate

sn-glycerol 1-phosphate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(S)-citramalate

ammonium

H⁺

Co²⁺

Mg²⁺

hydrogencarbonate

nitrate

phosphate

diphosphate

chloride

putrescine

dehydrospermidine

spermidine

L-cysteate

3-sulfopyruvate

3-hydroxypropanoyl-CoA

3'-dephospho-CoA

phenylacetyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

isobutanoyl-CoA

2-methylacetoacetyl-CoA

acetyl-CoA

propanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

methane