an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

phosphoenolpyruvate

CO₂

oxaloacetate

H₂O

glycerone phosphate

S-adenosyl 3-(methylsulfanyl)propylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

5-phospho-β-D-ribosylamine

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

anthranilate

α-D-glucosamine 1-phosphate

3-deoxy-D-arabino-heptulosonate 7-phosphate

propanoyl phosphate

2-C-methyl-D-erythritol 4-phosphate

3-methyl-2-oxobutanoate

(S)-3-methyl-2-oxopentanoate

(R)-2,3-dihydroxy-3-methylpentanoate

(2S)-2-isopropylmalate

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

hydrogen peroxide

4'-phosphopantetheine

carboxyphosphate

carbamoyl phosphate

(indol-3 yl)acetyl-CoA

(indol-3-yl)pyruvate

citrate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

oxalosuccinate

S-methyl-5'-thioadenosine

imidazole acetol-phosphate

D-erythro-imidazole-glycerol-phosphate

adenosine 5'-phosphosulfate

adenosine 5'-phosphoselenate

γ-L-glutamyl 5-phosphate

α-ribazole 5'-phosphate

β-nicotinate D-ribonucleotide

5,6-dimethylbenzimidazole

5-aminolevulinate

(S)-4-amino-5-oxopentanoate

O-acetyl-L-serine

hydrogen selenide

3-phosphooxypyruvate

thiamine diphosphate

thiamine phosphate

coproporphyrinogen III

DNA without lesion

(2S)-2-amino-3-oxo-4-phosphooxybutanoate

3-amino-1-hydroxyacetone 1-phosphate

4-phosphooxy-L-threonine

quinolinate

carbon monoxide

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

nicotinate adenine dinucleotide

selenophosphate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

orotidine 5'-phosphate

N-(5-phosphoribosyl)-anthranilate

2-iminoacetate

5-phospho-α-D-ribose 1,2-cyclic phosphate

α-D-ribose-1-methylphosphonate 5-phosphate

acetyl phosphate

8-amino-7-oxononanoate

pimeloyl-CoA

4-aminobutanoate

isopentenyl diphosphate

glycolate

3-deoxy-α-D-manno-2-octulosonate

3-deoxy-D-manno-octulosonate 8-phosphate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

2-oxovalerate

3-ethylmalate

4-methyl-2-oxopentanoate

(2S)-2-isopropyl-3-oxosuccinate

prephenate

prenyl diphosphate

lipid A disaccharide (E. coli)

lipid X

ADP-L-glycero-β-D-manno-heptose

D-glycero-β-D-manno-heptose 1-phosphate

D-glycero-β-D-manno-heptose 1,7-bisphosphate

creatinine

5-oxo-L-proline

(E)-glutaconate

methyl-1,4-benzoquinol

2-methyl-1,4-benzoquinone

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

isochorismate

(S)-dihydroorotate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

5-amino-6-(D-ribitylamino)uracil

1-deoxy-L-glycero-tetrulose 4-phosphate

L-β-lysine

(R)-pantothenate

2-dehydropantoate

histidinol

L-histidinol phosphate

3-dehydroshikimate

3-dehydroquinate

N-carbamoylputrescine

(R)-4'-phosphopantothenoyl-L-cysteine

5-deoxy-α-ribose 1-phosphate

S-methyl-5-thio-α-D-ribose 1-phosphate

carbonic acid

(3R,5S)-3-hydroxy-1-pyrroline-5-carboxylate

hydrogenobyrinate a,c-diamide

hydrogenobyrinate

O-ureido-L-homoserine

L-arginino-succinate

canavaninosuccinate

L-canavanine

histidinal

porphobilinogen

preuroporphyrinogen

β-D-ribosylnicotinate

5-(methylsulfanyl)-ribulose 1-phosphate

hydroxylamine

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

4-prenylphlorisobutyrophenone

7-carboxy-7-deazaguanine

(R)-4'-phosphopantothenate

xanthine

glutathione disulfide

shikimate

2-amino-3-carboxymuconate-6-semialdehyde

urea

N⁵-carboxyaminoimidazole ribonucleotide

(3R)-3-hydroxy-2-oxo-4 phosphooxybutanoate

lipid IV_A

glutathioselenol

selenodiglutathione

(L-seryl)adenylate

(2,3-dihydroxybenzoyl)adenylate

1,2-dihydro-β-NADP

enol-phenylpyruvate

ammonia

bisorganyltrisulfane

(R)-2-hydroxyglutarate

(S)-2-hydroxyglutarate

2-octaprenylphenol

(S)-3-hydroxy-isobutanoate

(S)-methylmalonate-semialdehyde

(R)-methylmalonate-semialdehyde

S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine

(2R)-2,3-dihydroxy-3-methylbutanoate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

2-chloroacetate

2-iminobutanoate

2-iminosuccinate

2-iminopropanoate

oxygen

hydrogen sulfide

protoporphyrinogen IX

Mg-protoporphyrin

protoporphyrin IX

coproporphyrinogen I

uroporphyrinogen-I

uroporphyrinogen-III

protoheme

cob(I)alamin

adenosylcobalamin

adenosyl-cob(III)yrinate a,c-diamide

cob(I)yrinate a,c-diamide

adenosylcobinamide

cob(I)inamide

cobalt-precorrin-2

cobalt-sirohydrochlorin

cobyrinate

cob(II)yrinate a,c-diamide

cob(II)yrinate c-monoamide

cobalt-precorrin-5A

cobalt-precorrin-4

hydrogen cyanide

nitrous oxide

ethylphosphate

phenylacetate

L-homocysteine

4-methylphenol

DNA with lesion

γ-L-glutamyl-L-cysteine

D-alanyl-D-alanine

carbamate

L-citrulline

L-methionine

L-aspartate

glycine

L-alanine

L-glutamate

L-glutamine

L-tryptophan

L-serine

L-arginine

L-tyrosine

L-threonine

L-phenylalanine

L-lysine

L-leucine

L-isoleucine

L-proline

L-valine

L-histidine

L-cysteine

L-aspartate 4-semialdehyde

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

O-phospho-L-homoserine

O-succinyl-L-homoserine

L-homoserine

L-glutamate-5-semialdehyde

S-sulfo-L-cysteine

L-ornithine

L-canaline

S-(4-hydroxy-nonenal-3-yl)-L-cysteine

L-selenocysteine

meso-diaminopimelate

L-aspartyl-4-phosphate

O-acetyl-L-homoserine

trans-4-hydroxy-L-proline

N-acetyl-L-ornithine

N-acetyl-L-citrulline

N-acetyl-L-glutamate

sarcosine

N-carbamoyl-L-aspartate

3-phospho-L-serine

L-cystathionine

L,L-diaminopimelate

D-alanine

D-glutamate

creatine

(R)-β-lysine

β-alanine

protocatechuate

2,3-dihydroxybenzoate

acetate

5-chloro-5-deoxy-D-ribonate

orotate

(R)-pantoate

(S)-1-pyrroline-5-carboxylate

(R)-lactate

pyruvate

formate

propanoate

2-oxobutanoate

2-oxoglutarate

5-chloro-4-hydroxy-2-oxopentanoate

glyoxylate

3-phenyl-2-oxopropanoate

3-oxoadipate

cis-aconitate

3-carboxy-cis,cis-muconate

D-threo-isocitrate

chorismate

fumarate

succinate

(S)-malate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

phlorisovalerophenone

(heptosyl)₂-Kdo₂-lipid A

heptosyl-Kdo₂-lipid A

3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine

3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine

trans,octacis-decaprenyl phosphate

(2E,6E)-farnesyl diphosphate

geranyl diphosphate

3-[(8Z,11E,13Z)-pentadeca-8,11,13-trien-1-yl] )catechol

dimeric urushiol peroxide

4-prenylphlorisovalerophenone

deoxycohumulone

deoxyhumulone

3-octaprenyl-4-hydroxybenzoate

di-trans,octa-cis-undecaprenyl phosphate

all-trans-octaprenyl diphosphate

geranylgeranyl diphosphate

1-oleoyl-2-palmitoyl-phosphatidylglycerol

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

1-(β-D ribofuranosyl)nicotinamide

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

ADP-α-D-glucose

GDP-α-D-mannose

GDP-α-D-glucose

GDP-α-D-mannuronate

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

dTDP-4-dehydro-β-L-rhamnose

dTDP-α-D-glucose

dTDP-β-L-rhamnose

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-α-D-glucose

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine

UDP-α-D-glucuronate

UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine

UDP-α-D-galactose

UDP-α-D-galactofuranose

UDP-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

CMP-3-deoxy-β-D-manno-octulosonate

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-sedoheptulose 7-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

4-phospho-D-erythronate

α-D-mannose 1-phosphate

α-D-glucopyranose 1-phosphate

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

α-D-ribose-1-phosphate

1-deoxy-D-xylulose 5-phosphate

D-xylulose 5-phosphate

aldehydo-D-arabinose 5-phosphate

D-arabinofuranose 5-phosphate

D-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

α,α-trehalose 6-phosphate

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

D-glyceraldehyde

aldehydo-D-ribose

β-D-ribofuranose

α-D-ribofuranose

glycerol

α,α-trehalose

maltotetraose

maltopentaose

maltotriose

maltohexaose

maltoheptaose

selaginose

8'-(3,4-dihydroxy-5-alkenyl)phenyl-3-[9'E,11'E,13'Z-pentadecatrienyl]catechol

ethanol

methanol

methylglyoxal

acetaldehyde

formaldehyde

menadione

caldariellaquinone

diacetyl

4-hydroxybenzoate

urate

menadiol

all trans-decaprenyl-2-methoxy-6-1,4-benzoquinol

6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol

caldariellaquinol

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

guanine

adenine

IMP

AMP

XMP

GMP

ATP

GTP

ITP

ADP

GDP

IDP

dGDP

dADP

dIDP

dGTP

dITP

dATP

hypoxanthine

adenosine

inosine

guanosine

xanthosine

2'-deoxyguanosine

2'-deoxyinosine

2'-deoxyadenosine

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

tetrahydromethanopterin

6-carboxy-5,6,7,8-tetrahydropterin

7,8-dihydroneopterin 3'-triphosphate

5,10-methylene-tetrahydromethanopterin

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

thio-molybdenum cofactor

MoO₂-molybdopterin cofactor

reduced riboflavin

FMNH₂

riboflavin

FMN

6,7-dimethyl-8-(1-D-ribityl)lumazine

uracil

preQ₁

isoguanine

CTP

UTP

UDP

CDP

dCDP

dUDP

dUTP

dCTP

dTTP

dTDP

dCMP

dTMP

dUMP

UMP

CMP

uridine

cytidine

2'-deoxyuridine

2'-deoxycytidine

sirohydrochlorin

precorrin-2

precorrin-6B

precorrin-8x

precorrin-7

precorrin-3A

precorrin-4

precorrin-3B

coenzyme A

adenylo-succinate

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-ATP

cyclic-AMP

ppGpp

pppGpp

1-(5-phospho-β-D-ribosyl)-AMP

8-oxo-GTP

8-oxo-dGTP

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

β-nicotinamide D-ribonucleotide

5-hydroxy-CTP

2-hydroxy-dATP

cyclic di-3',5'-guanylate

NADP⁺

NAD⁺

NADPH

NADH

glycine betaine

(S)-NADHX

(R)-NADHX

nicotinate

pyridoxine 5'-phosphate

pyridoxal 5'-phosphate

pyridoxamine 5'-phosphate

methane

succinyl-CoA

acetyl-CoA

3'-dephospho-CoA

2-methylacetoacetyl-CoA

isobutanoyl-CoA

malonyl-CoA

(2R)-ethylmalonyl-CoA

(2S)-ethylmalonyl-CoA

(E)-glutaconyl-CoA

phenylacetyl-CoA

(R)-2-hydroxyglutaryl-CoA

4-hydroxybenzoyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

propanoyl-CoA

(S)-3-hydroxybutanoyl-CoA

crotonyl-CoA

(R)-methylmalonyl-CoA

(S)-methylmalonyl-CoA

S-(hydroxymethyl)glutathione

glutathione

(R)-S-lactoylglutathione

3-sulfopyruvate

L-cysteate

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

methanethiol

thiocyanate

S-sulfanylglutathione

betaine aldehyde hydrate

choline

betaine aldehyde

agmatine

spermidine

putrescine

(2Z)-2-aminobut-2-enoate

2-aminoprop-2-enoate

superoxide

hydroxyl radical

Fe³⁺

Mo²⁺

Co²⁺

Mg²⁺

Fe²⁺

ammonium

K⁺

H⁺

molybdate

nitrite

hydrogencarbonate

selenate

thiosulfate

sulfite

selenide

OH^-

selenite

hydrogensulfite

sulfate

chloride

phosphonate

phosphate

diphosphate

triphosphate

preQ₀