an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

nicotinate adenine dinucleotide

glycerone phosphate

S-methyl-5-thio-α-D-ribose 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

urea

2-(α-hydroxyethyl)thiamine diphosphate

1-deoxy-L-glycero-tetrulose 4-phosphate

oxalosuccinate

(S)-dihydroorotate

hydrogen selenide

O-acetyl-L-serine

citrate

orotidine 5'-phosphate

2-methyl-1,4-benzoquinone

methyl-1,4-benzoquinol

4-amino-4-deoxychorismate

hydroxypyruvate

L-tartrate

S-adenosyl 3-(methylsulfanyl)propylamine

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

isopentenyl diphosphate

5-amino-6-(5-phospho-D-ribitylamino)uracil

pseudouridine 5'-phosphate

β-nicotinate D-ribonucleotide

4-fumaryl-acetoacetate

acetoacetate

methylamine

dihydrolipoamide

hydrogen peroxide

lipoamide

L-canavanine

D-erythro-imidazole-glycerol-phosphate

histidinol

O-ureido-L-homoserine

canavaninosuccinate

histidinal

L-arginino-succinate

ammonia

carbamoyl phosphate

imidazole acetol-phosphate

L-histidinol phosphate

3-hydroxypropanoate

2-phosphoglycolate

3'-phosphoadenylyl-sulfate

prenyl diphosphate

coproporphyrinogen III

3-phosphooxypyruvate

porphobilinogen

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

(R)-4-phosphopantoate

oxaloacetate

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

enol-phenylpyruvate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

phosphoenolpyruvate

myosin light-chain phosphate

a [myosin light-chain] L-serine

(R)-4'-phosphopantothenate

5-amino-6-(D-ribitylamino)uracil

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

3-methyl-2-oxobutanoate

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

cyclohexane-1-carbonyl-CoA

cyclohexane-1-carboxylate

3-oxopimeloyl-CoA

3-hydroxypimeloyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

cyclohex-1,5-diene-1-carbonyl-CoA

crotonate

2-dehydropantoate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

thiamine phosphate

(R)-mevalonate

thiamine diphosphate

glycolate

2-dehydro-3-deoxy-D-gluconate

hexulose 6-phosphate

(R)-mevalonate diphosphate

quinolinate

H₂

H₂O

muconolactone

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

cis,cis-muconate

(lipoyl)adenylate

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

CO₂

N-succinyl-L,L-2,6-diaminopimelate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

preuroporphyrinogen

S-ribosyl-L-homocysteine

autoinducer 2

4-prenylphlorisobutyrophenone

4-aminobutanoate

succinate semialdehyde

3-oxopropanoate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

(R)-5-phosphomevalonate

S-methyl-5'-thioadenosine

(25S)-3-oxocholest-4-en-26-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

2-iminosuccinate

2-iminobutanoate

2-octaprenylphenol

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

myo-inositol

1D-myo-inositol 3-monophosphate

(3S)-linalool

(3R)-linalool

(2E,6E)-farnesyl diphosphate

pristanate

agmatine

dehydrospermidine

putrescine

spermidine

spermine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

(2Z)-2-aminobut-2-enoate

protoporphyrinogen IX

uroporphyrinogen-I

uroporphyrinogen-III

siroheme

protoheme

Fe³⁺

Na⁺

ammonium

H⁺

Co²⁺

Mn²⁺

Zn²⁺

Fe²⁺

sulfite

thiosulfate

molybdate

hydrogencarbonate

nitrate

sulfate

OH^-

hydrogensulfite

selenate

tungstate

phosphate

triphosphate

diphosphate

chloride

trimethyl sulfonium

hydroxyl radical

hydrogen sulfide

oxygen

(R)-lipoate

coenzyme A

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylene-tetrahydromethanopterin

tetrahydromethanopterin

nicotinate

riboflavin

pyridoxal 5'-phosphate

4-aminobenzoate

menaquinol-8

demethylmenaquinol-8

L-serine

L-threonine

L-glutamine

L-cysteine

glycine

L-asparagine

L-tyrosine

L-histidine

L-arginine

L-aspartate

L-glutamate

β-alanine

L-leucine

L-proline

L-alanine

O-acetyl-L-homoserine

N-carbamoyl-L-aspartate

sarcosine

3-phospho-L-serine

L-phenylalanine

L-citrulline

S-sulfo-L-cysteine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

L-homocysteine

L-homoserine

L-aspartate 4-semialdehyde

L-ornithine

L-glutamate-5-semialdehyde

O-phospho-L-homoserine

O-succinyl-L-homoserine

L-selenocysteine

L-methionine

L-cystathionine

L,L-diaminopimelate

2-chloroacetate

β-D-glucopyranose

α-D-glucopyranose

D-glyceraldehyde

acetaldehyde

formaldehyde

(S)-lactaldehyde

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

sn-glycerol 1-phosphate

3-phospho-D-glyceroyl-phosphate

(R)-glycerate

3-phospho-D-glycerate

2-phospho-D-glycerate

dimethyl sulfide

methanethiol

4-methyl-5-(2-phosphooxyethyl)thiazole

L-cysteate

3-sulfopyruvate

FMN

FAD

(S)-NADHX

(R)-NADHX

NADH

NADPH

NADP⁺

NAD⁺

D-glucono-1,5-lactone

2-methylacetoacetyl-CoA

succinyl-CoA

vinylacetyl-CoA

4-hydroxybutanoyl-CoA

3-hydroxypropanoyl-CoA

3'-dephospho-CoA

acryloyl-CoA

dihomo γ-linolenoyl-CoA

glutaryl-CoA

(E)-glutaconyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

2-methylfumaryl-CoA

3-methylfumaryl-CoA

(2R,3S)-β-methylmalyl-CoA

acetyl-CoA

isobutanoyl-CoA

linoleoyl-CoA

malonyl-CoA

α-linolenoyl-CoA

(3S)-citramalyl-CoA

(R)-methylmalonyl-CoA

(S)-methylmalonyl-CoA

crotonyl-CoA

phytenoyl-CoA

oleoyl-CoA

(Z)-15-tetracosenoyl-CoA

cerotoyl-CoA

2-carboxy-cerotoyl-CoA

lauroyl-CoA

decanoyl-CoA

octanoyl-CoA

propanoyl-CoA

pristanoyl-CoA

stearoyl-CoA

icosanoyl-CoA

myristoyl-CoA

palmitoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

(S)-3-hydroxybutanoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

unsaturated CDP-archaeol

saturated CDP-archaeol

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

geranyl diphosphate

di-trans,octa-cis-undecaprenyl phosphate

geranylgeranyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

3-octaprenyl-4-hydroxybenzoate

phlorisovalerophenone

deoxyhumulone

deoxycohumulone

4-prenylphlorisovalerophenone

chorismate

fumarate

succinate

(S)-malate

orotate

acetate

D-gluconate

(R)-pantoate

(S)-1-pyrroline-5-carboxylate

4-hydroxybutanoate

(15Z)-tetracosenoate

laurate

decanoate

octanoate

oleate

di-homo-γ-linolenate

linoleate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

α-linolenate

phytenate

stearate

arachidate

myristate

palmitate

pyruvate

2-oxoglutarate

2-oxobutanoate

glyoxylate

3-phenyl-2-oxopropanoate

cis-aconitate

D-threo-isocitrate

formate

maltotriose

maltotetraose

sucrose

β-D-fructofuranose

N-acetyl-β-D-glucosamine

D-ribulose-1,5-bisphosphate

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

dTDP-α-D-glucose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

UDP-α-D-glucose

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

sucrose 6^F-phosphate

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-fructose 1,6-bisphosphate

L-fuculose 1-phosphate

β-D-glucopyranose 1-phosphate

α-D-mannose 1-phosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-mannopyranose 6-phosphate

5,10-methenyltetrahydrofolate mono-L-glutamate

(S)-3-hydroxy-isobutanoate

IMP

XMP

adenylo-succinate

GMP

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

AMP

dGDP

dGTP

ITP

8-oxo-GTP

8-oxo-dGTP

isoguanine

IDP

dADP

dATP

ADP

GTP

GDP

dAMP

dGMP

2'-deoxyadenosine

2'-deoxyguanosine

ATP

2-hydroxy-dATP

5-hydroxy-CTP

UDP

CDP

UMP

CMP

UTP

CTP

β-nicotinamide D-ribonucleotide

dCDP

dUDP

dTDP

dCTP

dUTP

dTTP

dCMP

dTMP

dUMP

thymidine

2'-deoxyuridine

2'-deoxycytidine

cytidine

uridine

adenosine

adenine

uracil

thymine

cytosine

7,8-dihydroneopterin 3'-triphosphate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

6,7-dimethyl-8-(1-D-ribityl)lumazine

cob(I)alamin

adenosylcobalamin

precorrin-1

precorrin-2

sirohydrochlorin

(S)-methylmalonate-semialdehyde

(R)-methylmalonate-semialdehyde