an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

urea

L-dehydro-ascorbate

α-D-galacturonate 1-phosphate

L-xylo-hex-3-ulono-1,4-lactone

L-gulono-1,4-lactone

4-maleyl-acetoacetate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

7-epicholate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

2-amino-3-carboxymuconate-6-semialdehyde

homogentisate

N⁵-carboxyaminoimidazole ribonucleotide

(3R)-3-hydroxy-2-oxo-4 phosphooxybutanoate

2-(α-hydroxyethyl)thiamine diphosphate

1,6-anhydro-N-acetyl-β-muramate

N-acetyl-D-muramate 6-phosphate

core oligosaccharide-lipid A (E. coli K-12 core type)

(S)-2-amino-6-oxohexanoate

lipid IV_A

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

α-D-glucosamine 1-phosphate

formamide

carboxynorspermidine

norspermidine

β-nicotinate D-ribonucleotide

thiamine diphosphate

N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate

quinolinate

2-iminoacetate

ADP-L-glycero-β-D-manno-heptose

N-succinyl-L,L-2,6-diaminopimelate

(S)-dihydroorotate

orotidine 5'-phosphate

3-phosphonopyruvate

adenosine 5'-phosphosulfate

3'-phosphoadenylyl-sulfate

S-adenosyl 3-(methylsulfanyl)propylamine

N-(5-phosphoribosyl)-anthranilate

prephenate

ADP-D-glycero-β-D-manno-heptose

D-glycero-β-D-manno-heptose 1,7-bisphosphate

D-glycero-β-D-manno-heptose 1-phosphate

nicotinate adenine dinucleotide

anthranilate

2-oleoylglycerol

preuroporphyrinogen

ammonia

1-deoxy-L-glycero-tetrulose 4-phosphate

(2E,4Z)-2-hydroxy-6-oxohepta-2,4-dienoate

(2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate

2-oxopent-4-enoate

DNA without lesion

3-phosphooxypyruvate

isopentenyl diphosphate

(S)-3-methyl-2-oxopentanoate

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

N¹-(5-phospho-β-D-ribosyl)glycinamide

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

3-deoxy-α-D-manno-2-octulosonate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

5-phospho-β-D-ribosylamine

3α,12α-dihydroxy-7-oxo-5β-cholan-24-oate

2-methyl-trans-aconitate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

carbon monoxide

carbonic acid

autoinducer 2

3-deoxy-D-manno-octulosonate 8-phosphate

H₂

(R)-pantothenate

4-amino-4-deoxychorismate

2-dehydropantoate

4-prenylphlorisobutyrophenone

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

2-C-methyl-D-erythritol 4-phosphate

L-histidinol phosphate

L-canavanine

selenophosphate

hydrogen selenide

histidinal

histidinol

γ-L-glutamyl 5-phosphate

porphobilinogen

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

lipid X

lipid A disaccharide (E. coli)

citrate

4-phosphooxy-L-threonine

(2S)-2-amino-3-oxo-4-phosphooxybutanoate

3-amino-1-hydroxyacetone 1-phosphate

glycolate

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

carbamoyl phosphate

prenyl diphosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

thiamine phosphate

N-acetylglutamyl-phosphate

5-(methylsulfanyl)-α-D-ribose

S-methyl-5'-thioadenosine

S-methyl-5-thio-α-D-ribose 1-phosphate

5-deoxy-α-ribose 1-phosphate

S-ribosyl-L-homocysteine

hydrogen peroxide

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

N-acetyl-L-glutamate 5-semialdehyde

acetyl phosphate

glycerone phosphate

5-amino-6-(D-ribitylamino)uracil

imidazole acetol-phosphate

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

(R)-4-phosphopantoate

(R)-4'-phosphopantothenate

shikimate

3-dehydroshikimate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

O-acetyl-L-serine

4-guanidinobutyramide

L-arginino-succinate

O-ureido-L-homoserine

canavaninosuccinate

(S)-2-acetolactate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-aceto-2-hydroxybutanoate

oxaloacetate

phosphoenolpyruvate

oxalosuccinate

4-fumaryl-acetoacetate

acetoacetate

coproporphyrinogen III

xanthine

D-erythro-imidazole-glycerol-phosphate

3-methyl-2-oxobutanoate

(2S)-2-isopropylmalate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

CO₂

H₂O

2-carboxy-L-threo-pentonate

2-carboxy-L-xylonolactone

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

2,3-dioxo-L-gulonate

cyclic- 3,4-O-oxalyl-L-threonate

enol-phenylpyruvate

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

dehydroascorbate (bicyclic form)

cyclic-2,3-O-oxalyl-L-threonate

(3E)-2-oxopent-3-enoate

(2E)-2-hydroxypenta-2,4-dienoate

1-piperideine 6-carboxylate

(2E,6E)-farnesyl diphosphate

DNA with lesion

protoheme

hydrogen cyanide

protoporphyrin IX

uroporphyrinogen-I

coproporphyrinogen I

uroporphyrinogen-III

protoporphyrinogen IX

hydrogen sulfide

oxygen

sn-glycerol 1-phosphate

sn-glycerol 3-phosphate

2,3-diphospho-D-glycerate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

(2R)-2,3-dihydroxy-3-methylbutanoate

N-acetyl-D-mannosamine 6-phosphate

N-acetyl-β-neuraminate 9-phosphate

1-oleoyl-2-lyso-glycerone phosphate

CMP-N-acetyl-β-neuraminate

5,10-methenyltetrahydrofolate mono-L-glutamate

2-octaprenylphenol

superoxide

monodehydroascorbate radical

N-acetyl-β-neuraminate

dimethyl sulfide

thiocyanate

methanethiol

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

L-cysteate

3-sulfopyruvate

methanesulfonate

1-butanesulfonate

isethionate

3-(N-morpholino)propanesulfonate

Fe³⁺

ammonium

H⁺

Mo²⁺

Ni²⁺

Fe²⁺

sulfate

thiosulfate

nitrite

nitrate

selenide

sulfite

hydrogencarbonate

hydrogensulfite

phosphonate

phosphate

diphosphate

trimethyl sulfonium

2-iminopropanoate

2-aminoprop-2-enoate

(2Z)-2-aminobut-2-enoate

agmatine

putrescine

spermidine

1-oleoyl-2-palmitoyl-phosphatidylglycerol

5'-deoxy-5'-fluoroadenosine

5-fluoro-5-deoxy-D-ribose 1-phosphate

5-chloro-5-deoxy-D-ribonate

5-chloro-4-hydroxy-2-oxopentanoate

5'-chloro-5'-deoxyadenosine

5-chloro-5-deoxyribose 1-phosphate

5-amino-4-imidazolecarboxyamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

nicotinamide

3α,7α,12β-trihydroxy-5β-cholan-24-oate

3α,7α-dihydroxy-12-oxo-5β-cholan-24-oate

3-dehydrocholate

isocholate

glycocholate

cholate

(+)-7-epi-jasmonate

(indol-3-yl)acetate

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

3'-dephospho-CoA

(+)-7-epi-jasmonoyl-CoA

trans-caffeoyl-CoA

trans-feruloyl-CoA

succinyl-CoA

malonyl-CoA

acetyl-CoA

oleoyl-CoA

propanoyl-CoA

stearoyl-CoA

palmitoyl-CoA

hexadecanedioyl-CoA

acetoacetyl-CoA

L-galactono-1,4-lactone

FAD

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

ubiquinol-8

menaquinol-8

demethylmenaquinol-8

3-demethylubiquinol-8

4-methylphenol

L-homocysteine

coenzyme A

MoO₂-molybdopterin cofactor

guanylyl molybdenum cofactor

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

7,8-dihydrofolate monoglutamate

L-ascorbate

riboflavin

nicotinate

pyridoxal 5'-phosphate

pyridoxine 5'-phosphate

(S)-1-pyrroline-5-carboxylate

6,7-dimethyl-8-(1-D-ribityl)lumazine

7,8-dihydroneopterin 3'-phosphate

7,8-dihydroneopterin

7,8-dihydromonapterin

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

7,8-dihydroneopterin 3'-triphosphate

6-(hydroxymethyl)-7,8-dihydropterin

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydropteroate

guanine

adenine

2'-deoxyadenosine

2'-deoxyguanosine

2'-deoxyinosine

inosine

guanosine

xanthosine

adenosine

hypoxanthine

dAMP

dGMP

dATP

dGTP

dITP

dADP

dGDP

dIDP

GDP

IDP

ADP

XMP

IMP

GMP

AMP

GTP

ITP

ATP

dCMP

orotate

dTDP

dTTP

CDP

CTP

dCDP

dCTP

dUDP

dUTP

UDP

UTP

dUMP

dTMP

UDP-α-D-galacturonate

UDP-3-O-(3-hydroxymyristoyl)-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-galactofuranose

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-α-D-glucose

UDP-α-D-galactose

UDP-α-D-glucuronate

UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-α-D-glucosamine

UDP-3-O-[(3R)-3-hydroxymyristoyl]-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-mannosaminuronate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-glucosamine

dTDP-3-amino-3,6-dideoxy-α-D-galactopyranose

dTDP-3-dehydro-6-deoxy-α-D-galactopyranose

dTDP-α-D-glucose

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

CMP

UMP

preQ₁

preQ₀

(indole-3-yl)acetonitrile

urate

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

catechol

4-aminobenzoate

chorismate

succinate

L-aspartate

fumarate

(S)-malate

cis-2-methylaconitate

(2S,3S)-2-methylcitrate

(2R,3S)-2-methylisocitrate

cis-aconitate

D-threo-isocitrate

(R)-lactate

propanoate

formate

acetate

pyruvate

oleate

stearate

palmitate

(R)-pantoate

aldehydo-D-galacturonate

aldehydo-D-glucuronate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

glyoxylate

2-oxobutanoate

2-oxoglutarate

L-serine

β-alanine

L-leucine

glycine

L-proline

L-alanine

L-glutamine

D-glutamate

L-glutamate

L-histidine

L-lysine

L-arginine

L-cysteine

L-tyrosine

L-asparagine

L-threonine

L-phenylalanine

L-tryptophan

D-alanine

L-saccharopine

L-aspartyl-4-phosphate

N-acetyl-L-ornithine

N-acetyl-L-glutamate

N-acetyl-L-methionine

N-carbamoyl-L-aspartate

O-acetyl-L-homoserine

3-phospho-L-serine

L-citrulline

L-valine

L-isoleucine

L-canaline

L-homoserine

L-aspartate 4-semialdehyde

O-phospho-L-homoserine

O-succinyl-L-homoserine

S-sulfo-L-cysteine

1-aminocyclopropane-1-carboxylate

L-glutamate-5-semialdehyde

L-ornithine

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

meso-diaminopimelate

L-selenocysteine

L-methionine

L,L-diaminopimelate

L-cystathionine

diacetyl

glycolaldehyde

3-(N-morpholino)propanal

acetaldehyde

formaldehyde

butan-1-al

(S)-lactaldehyde

D-glyceraldehyde

L-glyceraldehyde

aldehydo-D-mannose

β-D-mannopyranose

aldehydo-D-ribose

α-D-ribofuranose

β-D-ribofuranose

butan-1-ol

ethanol

methanol

glycerol

D-mannitol

(3R)-linalool

(3S)-linalool

ethylene glycol

myo-inositol

1D-myo-inositol 3-monophosphate

1D-myo-inositol 1-monophosphate

1-C16:0-α,ω-dicarboxyl-2-lysophosphatidate

1-oleoyl-sn-glycerol 3-phosphate

1-palmitoyl-sn-glycero-3-phosphocholine

1-(oleoyl)-sn-glycero-3-phosphoethanolamine

1,2-dipalmitoyl-sn-glycero-3-phosphocholine

dioleoyl phosphatidate

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

1-18:1-2-18:1-phosphatidylethanolamine

trans,octacis-decaprenyl phosphate

di-trans,octa-cis-undecaprenyl phosphate

geranyl diphosphate

geranylgeranyl diphosphate

mono-trans,octa-cis-decaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

3-octaprenyl-4-hydroxybenzoate

galactosyl-glucosyl-(heptosyl)₃-Kdo₂-lipid A-bisphosphate

galactosyl-(glucosyl)₃-(heptosyl)₃-Kdo₂-lipid A-bisphosphate

galactosyl-(glucosyl)₂-(heptosyl)₃-Kdo₂-lipid A-bisphosphate

glucosyl-(heptosyl)₃-Kdo₂-lipid A-bisphosphate

glucosyl-(heptosyl)₃-Kdo₂-lipid A-phosphate

glucosyl-(heptosyl)₂-Kdo₂-lipid A-phosphate

glucosyl-(heptosyl)₂-Kdo₂-lipid A

heptosyl-Kdo₂-lipid IV_A

α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid A

α-Kdo-(2->4)-α-Kdo-(2->6)-lipid IV_A

α-Kdo-(2→6)-lipid IV_A

heptosyl-Kdo₂-lipid A

(heptosyl)₂-Kdo₂-lipid A

phlorisovalerophenone

deoxyhumulone

4-prenylphlorisovalerophenone

deoxycohumulone

L-alanyl-γ-D-glutamyl-meso-diaminopimelate

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

D-alanyl-D-alanine

sucrose

N-acetyl-α-D-muramoyl-L-alanine(1-)

N-acetylmuramate

N-acetyl-α-D-glucosamine 1-phosphate

N-acetyl-α-D-mannosamine

N-acetyl-β-D-glucosamine

β-D-fructofuranose

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide)

a peptidoglycan dimer (mycobacteria)

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

a peptidoglycan with D,D cross-links (mycobacteria)

a peptidoglycan with L,D cross-links (mycobacteria)

a peptidoglycan dimer (meso-diaminopimelate containing)

a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

sucrose 6^F-phosphate

CMP-3-deoxy-β-D-manno-octulosonate

GDP-4-dehydro-6-deoxy-β-L-galactose

GDP-4-dehydro-α-D-rhamnose

GDP-α-D-mannuronate

GDP-α-D-mannose

GDP-β-L-fucose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

4-phospho-D-erythronate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-mannopyranose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

aldehydo-D-arabinose 5-phosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

L-fuculose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

aldehydo-L-galactonate

L-gulonate

1-(5-phospho-β-D-ribosyl)-AMP

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-ATP

5'-deoxyadenosine

β-nicotinamide D-ribonucleotide

2-iminosuccinate

2-iminobutanoate