an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

2-succinylbenzoate

(S)-2-aceto-2-hydroxybutanoate

(R)-mevalonate

(R)-5-phosphomevalonate

1,4-dihydroxy-2-naphthoate

(S)-2-acetolactate

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

orotidine 5'-phosphate

1,4-dihydroxy-2-naphthoyl-CoA

carbamoyl phosphate

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

(S)-2-amino-6-oxohexanoate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

glycerone phosphate

itaconate

(R)-4-phosphopantoate

4-amino-2-methyl-5-pyrimidinemethanol

4-prenylphlorisobutyrophenone

(2S)-2-isopropylmalate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

nigerose

2-(α-hydroxyethyl)thiamine diphosphate

(R)-4'-phosphopantothenoyl-L-cysteine

4'-phosphopantetheine

4-amino-4-deoxychorismate

3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA

adenosine 5'-phosphosulfate

5-enolpyruvoyl-shikimate 3-phosphate

adenosine 5'-phosphoselenate

5-dehydro-D-gluconate

α-ribazole

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

H₂O

α-ribazole 5'-phosphate

succinate semialdehyde

2-keto-L-gulonate

2-keto-D-gluconate

2,5-didehydro-D-gluconate

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

CO₂

2-dehydro-3-deoxy-D-gluconate

2-carboxy-L-threo-pentonate

2-carboxy-L-xylonolactone

2,3-dioxo-L-gulonate

cyclic- 3,4-O-oxalyl-L-threonate

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

dehydroascorbate (bicyclic form)

cyclic-2,3-O-oxalyl-L-threonate

enol-phenylpyruvate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

pyruvic oxime

1-piperideine 6-carboxylate

L-dehydro-ascorbate

L-xylo-hex-3-ulono-1,4-lactone

L-gulono-1,4-lactone

α-D-galacturonate 1-phosphate

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

cyclohexane-1-carbonyl-CoA

cyclohexane-1-carboxylate

3-oxopimeloyl-CoA

3-hydroxypimeloyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

cyclohex-1,5-diene-1-carbonyl-CoA

crotonate

hydroxylamine

shikimate

2-dehydropantoate

(R)-mevalonate diphosphate

4-hydroxy-2-nonenal

preuroporphyrinogen

5,6-dimethylbenzimidazole

(R)-1-amino-2-propanol O-2-phosphate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

(S)-2,3,4,5-tetrahydrodipicolinate

urea

N-succinyl-2-amino-6-ketopimelate

formamide

α-D-glucosamine 1-phosphate

(2S)-lactyl-2-diphospho-5'-guanosine

H₂

coproporphyrinogen III

isochorismate

N-succinyl-L,L-2,6-diaminopimelate

N²-succinylglutamate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

1-deoxy-L-glycero-tetrulose 4-phosphate

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

hydrogen selenide

squalene

presqualene diphosphate

3-methyl-2-oxobutanoate

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-3-methyl-2-oxopentanoate

prephytoene diphosphate

(R)-4'-phosphopantothenate

3-dehydroquinate

5-oxo-L-proline

pseudouridine 5'-phosphate

4,5-dihydroxyphthalate

prephenate

hydroxypyruvate

(E)-2-benzylidenesuccinyl-CoA

2-carboxymethyl-3-hydroxyphenylpropanoyl-CoA

5-aminolevulinate

arsenite

porphobilinogen

4-hydroxybenzaldehyde

3-dehydroshikimate

3-deoxy-D-arabino-heptulosonate 7-phosphate

2,3-didehydroadipyl-CoA

(R)-1-aminopropan-2-ol

cis-coumarinic acid-β-D-glucoside

phosphoenolpyruvate

carbon monoxide

citrate

3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA

(E)-4-coumaroyl-CoA

7,8-didemethyl-8-hydroxy-5-deazariboflavin

oxalate

γ-L-glutamyl 5-phosphate

2-dehydro-3-deoxy-D-gluconate 6-phosphate

nicotinate adenine dinucleotide

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

S-ribosyl-L-homocysteine

autoinducer 2

3-phosphooxypyruvate

shikimate 3-phosphate

N-acetyl-L-glutamate 5-semialdehyde

thiamine phosphate

N-acetylglutamyl-phosphate

oxalosuccinate

L-canavanine

O-acetyl-L-serine

thiamine diphosphate

L-arginino-succinate

carbonic acid

O-ureido-L-homoserine

tartronate semialdehyde

canavaninosuccinate

isopentenyl diphosphate

prenyl diphosphate

ammonia

β-nicotinate D-ribonucleotide

oxaloacetate

quinolinate

histidinal

histidinol

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

5-amino-6-(D-ribitylamino)uracil

methylsalicylate

(S)-4-amino-5-oxopentanoate

5-phospho-β-D-ribosylamine

N¹-(5-phospho-β-D-ribosyl)glycinamide

dihydrolipoamide

lipoamide

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

salicyl alcohol

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

(S)-dihydroorotate

creatinine

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

hydrogen peroxide

N-(5-phosphoribosyl)-anthranilate

anthranilate

L-histidinol phosphate

hypoglycin B

L-methionine

L-serine

L-cystathionine

L-glutamine

L,L-diaminopimelate

L-selenocysteine

L-tyrosine

L-glutamate

L-cysteine

L-aspartyl-4-phosphate

L-isoleucine

L-leucine

L-valine

L-alanine

L-lysine

L-asparagine

L-threonine

L-histidine

L-aspartate

L-arginine

L-ornithine

L-proline

L-tryptophan

L-phenylalanine

N-formimino-L-glutamate

N-acetyl-L-aspartate

N-carbamoyl-L-aspartate

glycine

L-citrulline

O-phospho-L-homoserine

hypoglycin A

L-aspartate 4-semialdehyde

O-succinyl-L-homoserine

L-canaline

S-sulfo-L-cysteine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

L-glutamate-5-semialdehyde

L-homoserine

L-homocysteine

meso-diaminopimelate

creatine

β-alanine

L-saccharopine

O-acetyl-L-homoserine

3-phospho-L-serine

N-acetyl-L-glutamate

UDP-α-D-galactose

lotaustralin

taxiphyllin

linustatin

linamarin

neolinustatin

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

β-D-fructose 1,6-bisphosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

α-D-ribose-1-phosphate

β-D-glucopyranose 1-phosphate

α-D-mannose 1-phosphate

α-D-galactose 1-phosphate

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-mannopyranose 6-phosphate

sucrose 6^F-phosphate

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

dTDP-β-L-rhamnose

dTDP-4-dehydro-β-L-rhamnose

dTDP-α-D-glucose

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

UDP-α-D-galacturonate

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-glucose

UDP-α-D-sulfoquinovopyranose

UDP-α-D-glucuronate

UDP-α-D-galactofuranose

UDP-N-acetyl-α-D-glucosamine

N-acetyl-α-D-mannosamine

α-D-glucopyranose

β-D-glucopyranose

α-D-galactopyranose

β-D-fructofuranose

D-xylulose

D-glyceraldehyde

glycolaldehyde

glycerol

maltotriose

β-D-cellobiose

sucrose

α-maltose

maltotetraose

aldehydo-D-galacturonate

D-mannonate

L-gulonate

aldehydo-L-galactonate

D-gluconate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

palmitate

2-oxoglutarate

pyruvate

2-oxobutanoate

glyoxylate

chorismate

(4S)-4-hydroxy-2-oxoglutarate

succinate

fumarate

(S)-malate

orotate

(R)-pantoate

acetate

aldehydo-D-glucuronate

(S)-1-pyrroline-5-carboxylate

(S)-lactate

(R)-lactate

(R)-glycerate

protocatechuate

salicylate

4-aminobenzoate

cis-aconitate

D-threo-isocitrate

formate

methyl (indol-3-yl)acetate

(indol-3-yl)acetate

dimethyl sulfide

glutathione

methanethiol

5-(2-hydroxyethyl)-4-methylthiazole

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

L-cysteate

3-sulfopyruvate

coenzyme M

(2E,6E)-farnesyl diphosphate

5,10-methenyltetrahydrofolate mono-L-glutamate

(glutathion-S-yl)-4-hydroxy-2-nonenal

2-iminobutanoate

2-iminosuccinate

2-octaprenylphenol

adenosylcobalamin 5'-phosphate

adenosyl-cobinamide phosphate

adenosylcobinamide-GDP

cobyrinate

cob(II)yrinate a,c-diamide

cobalt-factor III

cobalt-sirohydrochlorin

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-5B

cobalt-precorrin-6A

cobalt-precorrin-4

cobalt-precorrin-5A

cobalt-precorrin-3

adenosylcobinamide

adenosylcobyrate

cob(I)yrinate a,c-diamide

adenosyl-cob(III)yrinate a,c-diamide

cob(I)inamide

cob(I)alamin

adenosylcobalamin

protoheme

(2Z)-2-aminobut-2-enoate

agmatine

dehydrospermidine

spermidine

putrescine

tyramine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

L-cysteinylglycine

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

γ-L-glutamyl-L-cysteine

coenzyme A

methyl-CoM

MoO₂-molybdopterin cofactor

guanylyl molybdenum cofactor

reduced coenzyme F₄₂₀-2

oxidized coenzyme F₄₂₀-0

oxidized coenzyme F₄₂₀-2

N¹⁰-formyldihydrofolate

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

5-formyl-tetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

thiamine

L-ascorbate

nicotinate

riboflavin

all-trans-retinol

pyridoxal 5'-phosphate

hydrogen cyanide

benzyl alcohol

myo-inositol

1D-myo-inositol 2-monophosphate

1D-myo-inositol 1-monophosphate

1D-myo-inositol 5-monophosphate

1D-myo-inositol 6-monophosphate

1D-myo-inositol 3-monophosphate

1D-myo-inositol 4-monophosphate

(3S)-linalool

(3R)-linalool

ethanol

methanol

FAD

FMNH₂

FMN

(S)-NADHX

(R)-NADHX

NADPH

NADH

NAD⁺

NADP⁺

ubiquinone-8

ubiquinol-8

demethylmenaquinol-8

protoporphyrinogen IX

protoporphyrin IX

uroporphyrinogen-I

coproporphyrinogen I

uroporphyrinogen-III

siroheme

Fe³⁺

H⁺

ammonium

Fe²⁺

Co²⁺

Cu²⁺

selenate

sulfite

thiosulfate

sulfate

selenide

hydrogencarbonate

superoxide

phosphate

diphosphate

triphosphate

chloride

trimethyl sulfonium

hydrogen sulfide

oxygen

2-hydroxy-2-methylpropanenitrile

(2R)-2-hydroxy-2-methylbutanenitrile

2-[(1R,6S)-1,6-dihydroxycyclohexa-2,4-dien-1-yl]acetyl-coA

benzyl-6-hydroxy-2-cyclohexene-on-oyl

6-hydroxy-2-cyclohexen-one-carboxylate

salicyl-6-hydroxy-2-cyclohexene-on-oyl

coumarinate

coumarin

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

diacetyl

methylglyoxal

acetaldehyde

(S)-lactaldehyde

1-(5-phospho-β-D-ribosyl)-AMP

adenylo-succinate

dATP

cyclic-AMP

dGTP

XMP

GMP

dAMP

dGMP

2'-deoxyadenosine

ATP

IMP

2'-deoxyguanosine

dGDP

GDP

dADP

ADP

XTP

dITP

dIMP

ITP

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-ATP

AMP

GTP

adenosine

cytidine

uridine

dCDP

dUDP

dTDP

CDP

UDP

dTMP

dCMP

dUMP

CMP

UMP

dUTP

dCTP

dTTP

UTP

CTP

β-nicotinamide D-ribonucleotide

reduced β-nicotinamide D-ribonucleotide

thymine

cytosine

uracil

adenine

5,6-dihydrothymine

5,6-dihydrouracil

reduced riboflavin

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydroneopterin 2',3'-cyclic phosphate

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydroneopterin 2'-phosphate

7,8-dihydroneopterin

7,8-dihydroneopterin 3'-phosphate

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydropteroate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

6,7-dimethyl-8-(1-D-ribityl)lumazine

aminomethylpyrimidine

formylaminopyrimidine

sirohydrochlorin

precorrin-1

precorrin-2

precorrin-5

precorrin-4

(R)-citramalate

sn-glycerol 1-phosphate

sn-glycerol 3-phosphate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

monodehydroascorbate radical

(2S)-2-phospholactate

1-chloro-2,4-dinitrobenzene

2,4-dinitrophenyl-S-glutathione

all-trans-retinyl palmitate

L-galactono-1,4-lactone

D-glucono-1,5-lactone

3'-dephospho-CoA

acetyl-CoA

itaconyl-CoA

4-hydroxybenzoyl-CoA

glutaryl-CoA

(E)-glutaconyl-CoA

succinyl-CoA

2-methylbutanoyl-CoA

2-methylacetoacetyl-CoA

(2E,5Z)-tetradecenoyl-CoA

methylacrylyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

(E)-2-methylcrotonoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA

(3S)-hydroxyadipyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

(2E)-dec-2-enoyl-CoA

crotonyl-CoA

propanoyl-CoA

palmitoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(S)-3-hydroxydecanoyl-CoA

(S)-3-hydroxy-(5Z)-tetradecenoyl-CoA

acetoacetyl-CoA

(S)-3-hydroxy-isobutanoyl-CoA

unsaturated CDP-archaeol

saturated CDP-archaeol

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

phytyl diphosphate

all-trans phytofluene

15-cis-phytoene

all-trans-phytoene

geranyl diphosphate

(3S)-2,3-epoxy-2,3-dihydrosqualene

all-trans-octaprenyl diphosphate

geranylgeranyl diphosphate

2-cis,6-trans,10-trans-geranylgeranyl diphosphate

3-octaprenyl-4-hydroxybenzoate

phlorisovalerophenone

deoxyhumulone

deoxycohumulone

4-prenylphlorisovalerophenone