an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

xanthine

2-phenylethanol

2-methylbutanal

2-methylbutanol

3-methylbutanal

3-methylbutanol

isobutanol

indole-3-glycol aldehyde

indole-3-glycol

3-methoxy-4-hydroxyphenylglycolaldehyde

5-hydroxyindole acetaldehyde

5-hydroxytryptophol

α-ribazole 5'-phosphate

α-ribazole

(S)-4-amino-5-oxopentanoate

porphobilinogen

5-aminolevulinate

preuroporphyrinogen

orotidine 5'-phosphate

glycolate

3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA

3-oxopropanoate

succinate semialdehyde

4-aminobutanoate

2-methyl-trans-aconitate

(2R,3S)-2,3-dimethylmalate

citrate

oxaloacetate

carbon monoxide

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA

3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]-3-hydroxypropanoyl-CoA

3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA

phosphoenolpyruvate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

formamide

urea

coproporphyrinogen III

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

N¹-(5-phospho-β-D-ribosyl)glycinamide

hydrogenobyrinate a,c-diamide

hydrogenobyrinate

H₂

(R)-pantothenate

2-dehydropantoate

3-methyl-2-oxobutanoate

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

(S)-3-methyl-2-oxopentanoate

(R)-2,3-dihydroxy-3-methylpentanoate

oxalosuccinate

S-methyl-5-thio-α-D-ribose 1-phosphate

nicotinate adenine dinucleotide

chlorite

2-isopropylmaleate

(2S)-2-isopropylmalate

ammonia

propionamide

(indol-3-yl)acetamide

4-guanidinobutanoate

4-guanidinobutyramide

acrylate

acrylamide

H₂O

glycerone phosphate

S-methyl-5'-thioadenosine

S-adenosyl 3-(methylsulfanyl)propylamine

CO₂

2-oxovalerate

3-ethylmalate

4-methyl-2-oxopentanoate

(2S)-2-isopropyl-3-oxosuccinate

(2R,3S)-3-isopropylmalate

2-hydroxy-5-carboxymethylmuconate semialdehyde

(4-hydroxyphenyl)acetate

(R)-4'-phosphopantothenoyl-L-cysteine

(R)-4'-phosphopantothenate

4'-phosphopantetheine

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

N²-acetyl-α-aminoadipate

thiamine phosphate

prephytoene diphosphate

presqualene diphosphate

squalene

2-arylpropanoate

2-aryl-2-methylmalonate

2-maleylacetate

5-carboxymethyl-2-hydroxymuconate

creatinine

1-pyrroline-2-carboxylate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

(lipoyl)adenylate

3-hydroxypropanoate

dihydromethanophenazine

CoB-CoM heterodisulfide

methanophenazine

coenzyme B

(R)-mevalonate diphosphate

(R)-5-phosphomevalonate

isopentenyl diphosphate

itaconate

(R)-mevalonate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

β-nicotinate D-ribonucleotide

3-phosphooxypyruvate

anthranilate

N-(5-phosphoribosyl)-anthranilate

O-ureido-L-homoserine

carbamoyl phosphate

pseudouridine 5'-phosphate

acetoacetate

4-fumaryl-acetoacetate

3-dehydroshikimate

3-dehydroquinate

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

shikimate

3-deoxy-D-arabino-heptulosonate 7-phosphate

prephenate

hydrogen peroxide

4-amino-4-deoxychorismate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

L-histidinol phosphate

imidazole acetol-phosphate

D-erythro-imidazole-glycerol-phosphate

histidinol

histidinal

(S)-dihydroorotate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-phospho-β-D-ribosylamine

canavaninosuccinate

L-arginino-succinate

L-canavanine

hydroxypyruvate

4-prenylphlorisobutyrophenone

prenyl diphosphate

γ-L-glutamyl 5-phosphate

(R)-1-amino-2-propanol O-2-phosphate

5-amino-6-(D-ribitylamino)uracil

1-deoxy-L-glycero-tetrulose 4-phosphate

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-amino-6-(5-phospho-D-ribitylamino)uracil

N⁵-carboxyaminoimidazole ribonucleotide

thiamine diphosphate

2-(α-hydroxyethyl)thiamine diphosphate

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

autoinducer 2

S-ribosyl-L-homocysteine

5,6-dimethylbenzimidazole

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

enol-phenylpyruvate

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

dialurate

citraconate

(2R,3S)-3-methylmalate

2-dehydro-3-deoxy-D-gluconate

2-dehydro-3-deoxy-D-gluconate 6-phosphate

adenosine 5'-phosphosulfate

chlorate

crotonate

cyclohex-1,5-diene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

3-hydroxypimeloyl-CoA

3-oxopimeloyl-CoA

cyclohexane-1-carboxylate

cyclohexane-1-carbonyl-CoA

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

4-amino-2-methyl-5-pyrimidinemethanol

(2E,6E)-farnesyl diphosphate

superoxide

2-octaprenylphenol

5,10-methenyltetrahydrofolate mono-L-glutamate

(R)-citramalate

(2R)-2,3-dihydroxy-3-methylbutanoate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

(R)-glycerate

2,3-diphospho-D-glycerate

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

sn-glycerol 1-phosphate

S⁰

oxygen

Hg⁰

hydrogen sulfide

uroporphyrinogen-III

protoporphyrinogen IX

Mg-protoporphyrin

protoporphyrin IX

uroporphyrinogen-I

siroheme

protoheme

hydrogen cyanide

cob(I)alamin

adenosylcobalamin

adenosylcobalamin 5'-phosphate

adenosylcobinamide-GDP

adenosylcobyrate

adenosyl-cob(III)yrinate a,c-diamide

cobyrinate

cob(II)yrinate a,c-diamide

cob(II)yrinate c-monoamide

cob(I)yrinate a,c-diamide

adenosylcobinamide

cob(I)inamide

cobalt-precorrin-5B

cobalt-precorrin-5A

cobalt-precorrin-2

cobalt-sirohydrochlorin

cobalt-precorrin-4

cobalt-precorrin-6A

cobalt-precorrin-6B

cobalt-precorrin-8

cobalt-precorrin-7

cobalt-precorrin-3

cobalt-factor III

adenosyl-cobinamide phosphate

phenylacetate

L-cysteinylglycine

N-acetyl-L-glutaminyl-L-glutamine amide

N-acetyl-L-glutaminyl-L-glutamine

L-homocysteine

2-iminobutanoate

hypoglycin B

L-2-aminoadipate

L-histidine

L-arginine

L-glutamate

L-proline

L-glutamine

L-leucine

glycine

L-serine

creatine

β-alanine

L-isoleucine

L-valine

L-phenylalanine

L-tryptophan

L-methionine

L-cysteine

L-ornithine

L-aspartate

L-asparagine

L-threonine

L-aspartyl-4-phosphate

L-tyrosine

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

L-citrulline

hypoglycin A

O-phospho-L-homoserine

L-homoserine

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

L-aspartate 4-semialdehyde

L-canaline

L-glutamate-5-semialdehyde

L-threonine 3-O-phosphate

3-phospho-L-serine

N-acetyl-L-glutamate

D-proline

hypoxanthine

GMP

5'-deoxyadenosine

IDP

ITP

AMP

ATP

GTP

GDP

ADP

XMP

dGDP

dGTP

dADP

dATP

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

IMP

dIMP

dITP

XTP

dIDP

adenylo-succinate

cyclic-AMP

2'-deoxyguanosine

2'-deoxyadenosine

dGMP

dAMP

ADP-D-ribose

ADP ribose 1''-phosphate

ADP ribose 1'',2''-cyclic phosphate

GDP-α-D-glucose

NAD⁺

NADP⁺

NADH

NADPH

dTDP-4-dehydro-β-L-rhamnose

dTDP-β-L-rhamnose

dTDP-α-D-glucose

UDP-α-D-glucose

UDP-α-D-sulfoquinovopyranose

adenine

uracil

dTMP

dUMP

dCMP

dTDP

dCDP

dUDP

dUTP

dCTP

dTTP

UDP

CDP

reduced β-nicotinamide D-ribonucleotide

β-nicotinamide D-ribonucleotide

CTP

UTP

UMP

CMP

2'-deoxyuridine

2'-deoxycytidine

thymidine

adenosine

uridine

cytidine

D-gluconate

sucrose

α-maltose

maltohexaose

maltoheptaose

maltopentaose

maltotetraose

maltotriose

5-phospho-α-D-ribose 1-diphosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

D-erythrose 4-phosphate

D-sedoheptulose 7-phosphate

α-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-mannopyranose 6-phosphate

L-xylulose 5-phosphate

D-xylulose 5-phosphate

aldehydo-D-ribose 5-phosphate

α-D-ribose 5-phosphate

β-D-ribose 5-phosphate

L-ribulose 5-phosphate

D-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

sucrose 6^F-phosphate

β-D-fructofuranose

D-glyceraldehyde

glycolaldehyde

α-D-ribofuranose

α-D-galactopyranose

β-D-galactopyranose

α-D-glucopyranose

β-D-glucopyranose

phlorisovalerophenone

deoxycohumulone

4-prenylphlorisovalerophenone

deoxyhumulone

(3S)-linalool

(3R)-linalool

geranyl diphosphate

all-trans-phytoene

15-cis-phytoene

phytyl diphosphate

(3S)-2,3-epoxy-2,3-dihydrosqualene

(3E)-dec-3-enoyl-CoA

(5E)-3-oxo-dodec-5-enoyl-CoA

(3Z,5E)-dodeca-3,5-dienoyl-CoA

5-cis, 7-trans-3-oxo-tetradecadienoyl-CoA

2-trans-nonenoyl-CoA

4-trans-3-oxo-undecenoyl-CoA

4-trans-undecenoyl-CoA

6-trans-3-oxo-tridecenoyl-CoA

4-cis-undecenoyl-CoA

6-cis, 3-oxo-tridecenoyl-CoA

unsaturated CDP-archaeol

saturated CDP-archaeol

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

2-cis,6-trans,10-trans-geranylgeranyl diphosphate

geranylgeranyl diphosphate

3-octaprenyl-4-hydroxybenzoate

phytol

propan-1-ol

ethanol

butan-1-ol

3,4-dihydroxyphenylglycolaldehyde

3,4-dihydroxyphenylglycol

3,4-dihydroxyphenylacetate

phenylacetaldehyde

(4-hydroxyphenyl)acetaldehyde

phytenal

isobutanal

1-propanal

acetaldehyde

butan-1-al

diacetyl

menadione

a coenzyme-A group

acetate

pyruvate

formate

propanoate

4-hydroxybutanoate

(2S,3S)-2-methylcitrate

cis-2-methylaconitate

(3E,5R)-5-carboxy-2-oxohept-3-enedioate

cis-aconitate

D-threo-isocitrate

chorismate

succinate

fumarate

(S)-malate

2-oxoglutarate

glyoxylate

2-oxobutanoate

5-chloro-4-hydroxy-2-oxopentanoate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

4-aminobenzoate

5-chloro-5-deoxy-D-ribonate

orotate

(S)-1-pyrroline-5-carboxylate

urate

4-tyrosol

menadiol

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

3-methoxy-4-hydroxyphenylglycol

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

(indole-3-yl)acetonitrile

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydroneopterin 2',3'-cyclic phosphate

molybdopterin adenine dinucleotide

cyclic pyranopterin phosphate

molybdopterin

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydroneopterin

7,8-dihydroneopterin 3'-phosphate

7,8-dihydroneopterin 2'-phosphate

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

7,8-dihydropteroate

5,6,7,8-tetrahydrofolate

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

7,8-dihydrofolate monoglutamate

N¹⁰-formyldihydrofolate

FMN

riboflavin

FAD

FMNH₂

reduced riboflavin

FADH₂

6,7-dimethyl-8-(1-D-ribityl)lumazine

sirohydrochlorin

precorrin-1

precorrin-2

precorrin-8x

precorrin-7

precorrin-6B

precorrin-3A

precorrin-3B

precorrin-4

precorrin-5

precorrin-6A

nicotinate

nicotinamide

thiamine

pyridoxal 5'-phosphate

coenzyme A

(R)-lipoate

coenzyme M

(R)-NADHX

(S)-NADHX

3'-dephospho-CoA

4-hydroxybenzoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxobutanoyl)-CoA

(+)-7-epi-jasmonoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxohexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-butanoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3-oxooctanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-hexanoyl-CoA

(3S)-citryl-CoA

phenylacetyl-CoA

(3S)-hydroxyadipyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA

succinyl-CoA

malonyl-CoA

acetyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

4-hydroxybutanoyl-CoA

acryloyl-CoA

3-hydroxypropanoyl-CoA

itaconyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

2-methylfumaryl-CoA

(2R,3S)-β-methylmalyl-CoA

3-methylfumaryl-CoA

(E)-glutaconyl-CoA

glutaryl-CoA

3-oxoadipyl-CoA

3-oxo-(5Z)-tetradecenoyl-CoA

3-oxo-myristoyl-CoA

3-oxooctanoyl-CoA

3-oxododecanoyl-CoA

3-oxodecanoyl-CoA

3-oxohexanoyl-CoA

acetoacetyl-CoA

hexanoyl-CoA

decanoyl-CoA

lauroyl-CoA

octanoyl-CoA

butanoyl-CoA

propanoyl-CoA

cerotoyl-CoA

2-carboxy-cerotoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

(S)-3-hydroxydecanoyl-CoA

(S)-3-hydroxyoctanoyl-CoA

(S)-3-hydroxyhexanoyl-CoA

(3Z)-dodec-3-enoyl-CoA

(3S)-citramalyl-CoA

crotonyl-CoA

(S)-methylmalonyl-CoA

(R)-methylmalonyl-CoA

trans-dienelactone

cis-dienelactone

D-galactono-1,4-lactone

D-glucono-1,5-lactone

(indol-3-yl)acetate

3,22-dioxochol-4-en-24-oyl-CoA

3-oxo-4-pregnene-20-carboxyl-CoA

3,24-dioxocholest-4-en-26-oyl-CoA

24-hydroxy-3-oxocholest-4-en-26-oyl-CoA

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

acetamide

(2Z)-2-aminobut-2-enoate

agmatine

spermidine

putrescine

spermine

dehydrospermidine

trimethyl sulfonium

sulfate

sulfite

thiosulfate

hydrogensulfite

hydrogencarbonate

molybdate

phosphate

triphosphate

diphosphate

chloride

Co²⁺

Mg²⁺

Hg²⁺

Fe²⁺

H⁺

ammonium

3-(methylsulfanyl)propanal

methionol

dimethyl sulfide

3-sulfopyruvate

L-cysteate

glutathione

thiocyanate