an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

enol-phenylpyruvate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

ammonia

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

cyclohexane-1-carbonyl-CoA

cyclohexane-1-carboxylate

3-oxopimeloyl-CoA

3-hydroxypimeloyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

cyclohex-1,5-diene-1-carbonyl-CoA

crotonate

1,4-dihydroxy-2-naphthoate

(2S)-2-isopropyl-3-oxosuccinate

5,6-dimethylbenzimidazole

dialurate

(R)-1-amino-2-propanol O-2-phosphate

S-ribosyl-L-homocysteine

autoinducer 2

N⁵-carboxyaminoimidazole ribonucleotide

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

5-amino-6-(5-phospho-D-ribitylamino)uracil

(R)-mevalonate diphosphate

xanthine

hexulose 6-phosphate

(S)-4-amino-5-oxopentanoate

3-phosphooxypyruvate

acrylamide

acrylate

4-guanidinobutyramide

4-guanidinobutanoate

(indol-3-yl)acetamide

propionamide

3-dehydroshikimate

(S)-2,3,4,5-tetrahydrodipicolinate

N-succinyl-2-amino-6-ketopimelate

quinolinate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

(S)-dihydroorotate

methanophenazine

dihydromethanophenazine

thiamine phosphate

thiamine diphosphate

hydrogen selenide

O-acetyl-L-serine

coenzyme B

CoB-CoM heterodisulfide

N-(5-phosphoribosyl)-anthranilate

anthranilate

histidinal

histidinol

(R)-4'-phosphopantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

itaconate

L-canavanine

urea

carbonic acid

oxalosuccinate

D-erythro-imidazole-glycerol-phosphate

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

oxalate

acetyl phosphate

L-arginino-succinate

canavaninosuccinate

S-adenosyl 3-(methylsulfanyl)propylamine

S-methyl-5'-thioadenosine

(R)-mevalonate

(R)-5-phosphomevalonate

2-oxopent-4-enoate

(S)-4-hydroxy-2-oxopentanoate

O-ureido-L-homoserine

N¹-(5-phospho-β-D-ribosyl)glycinamide

orotidine 5'-phosphate

N-methylhydantoin

imidazole acetaldehyde

4-imidazoleacetate

5-hydroxyindole acetaldehyde

5-hydroxyindole acetate

3-methoxy-4-hydroxyphenylglycolaldehyde

3,4-dihydroxyphenylacetaldehyde

prop-2-ynal

propynoate

D-glucurono-6,3-lactone

4-acetamidobutanal

4-acetamidobutanoate

dimethylsulfoniopropanoate

dihydroxyacetone

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

1-deoxy-L-glycero-tetrulose 4-phosphate

β-nicotinate D-ribonucleotide

nicotinate adenine dinucleotide

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

7,8-didemethyl-8-hydroxy-5-deazariboflavin

(2S)-lactyl-2-diphospho-5'-guanosine

4-amino-4-deoxychorismate

preuroporphyrinogen

shikimate

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

pseudouridine 5'-phosphate

5-phospho-β-D-ribosylamine

α-ribazole

α-ribazole 5'-phosphate

arsenite

5-aminolevulinate

porphobilinogen

2-phosphoglycolate

glycolate

5-amino-6-(D-ribitylamino)uracil

(2S)-2-isopropylmalate

phosphoenolpyruvate

shikimate 3-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

carbon monoxide

isopentenyl diphosphate

prenyl diphosphate

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

prephenate

CO₂

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

oxaloacetate

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

H₂

selenophosphate

3-deoxy-D-arabino-heptulosonate 7-phosphate

3-dehydroquinate

imidazole acetol-phosphate

L-histidinol phosphate

carbamoyl phosphate

4'-phosphopantetheine

3-methyl-2-oxobutanoate

4-methyl-2-oxopentanoate

(S)-3-methyl-2-oxopentanoate

glycerone phosphate

H₂O

(2E,6E)-farnesyl diphosphate

pristanate

glutaryl-CoA

2-methylbutanoyl-CoA

(E)-2-methylcrotonoyl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

(R)-2-hydroxyglutaryl-CoA

(E)-glutaconyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

itaconyl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

succinyl-CoA

2-methylacetoacetyl-CoA

acetyl-CoA

3'-dephospho-CoA

crotonyl-CoA

phytenoyl-CoA

oleoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

(Z)-15-tetracosenoyl-CoA

butanoyl-CoA

propanoyl-CoA

octanoyl-CoA

decanoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

FMNH₂

FMN

FAD

(S)-NADHX

(R)-NADHX

NADH

NADPH

NAD⁺

NADP⁺

caldariellaquinol

menaquinol-8

menaquinol-7

menaquinol-9

menaquinol-6

menaquinol-10

menaquinol-11

menaquinol-12

menaquinol-13

demethylmenaquinol-8

demethylmenaquinol-7

demethylmenaquinol-9

demethylmenaquinol-6

demethylmenaquinol-10

demethylmenaquinol-11

demethylmenaquinol-12

demethylmenaquinol-13

caldariellaquinone

tetrahydrosarcinapterin

5-methyl-tetrahydrosarcinapterin

coenzyme M

methyl-CoM

coenzyme A

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

oxidized coenzyme F₄₂₀-0

7,8-dihydrofolate monoglutamate

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

5-formyl-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

nicotinamide

thiamine

nicotinate

riboflavin

pyridoxal 5'-phosphate

guanine

adenine

2'-deoxyadenosine

2'-deoxyguanosine

2'-deoxyinosine

inosine

guanosine

xanthosine

adenosine

hypoxanthine

dAMP

dGMP

dATP

dGTP

dITP

dADP

dGDP

dIDP

IDP

GDP

ADP

IMP

XMP

GMP

AMP

ITP

XTP

GTP

ATP

5,6-dihydrouracil

5,6-dihydrothymine

orotate

dTDP

dTTP

dCTP

dUDP

dUTP

uracil

dCMP

dCDP

UDP

CDP

UTP

CTP

dUMP

dTMP

cytidine

uridine

thymidine

2'-deoxycytidine

2'-deoxyuridine

thymine

UMP

CMP

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-mannosamine

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-glucosamine

adenosylcobalamin

cobalt-precorrin-3

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-5B

cobalt-precorrin-6A

cobalt-precorrin-4

cobalt-precorrin-5A

precorrin-8x

precorrin-1

precorrin-2

cobalt-precorrin-2

cobyrinate

sirohydrochlorin

6,7-dimethyl-8-(1-D-ribityl)lumazine

7,8-dihydroneopterin 2'-phosphate

7,8-dihydroneopterin 3'-phosphate

7,8-dihydroneopterin

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydroneopterin 2',3'-cyclic phosphate

7,8-dihydroneopterin 3'-triphosphate

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

7,8-dihydropteroate

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

salicylaldehyde

3-hexaprenyl-4-hydroxybenzoate

4-hydroxybenzoate

salicylate

4-aminobenzoate

benzoate

vanillyl mandelate

benzaldehyde

(indol-3-yl)acetaldehyde

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

3,4-dihydroxyphenylglycolaldehyde

3,4-dihydroxymandelate

3,4-dihydroxyphenylacetate

L-citrulline

L-methionine

L-arginine

L-lysine

L-histidine

glycine

L-tyrosine

L-tryptophan

L-glutamine

L-alanine

L-threonine

L-phenylalanine

L-serine

L-aspartate

L-asparagine

L-valine

L-leucine

L-isoleucine

L-glutamate

L-cysteine

L-canaline

L-homocysteine

S-adenosyl-L-homocysteine

L-ornithine

O-phospho-L-homoserine

S-adenosyl-L-methionine

L-homoserine

L-aspartate 4-semialdehyde

meso-diaminopimelate

L-selenocysteine

L,L-diaminopimelate

L-aspartyl-4-phosphate

N-acetyl-L-ornithine

N-carbamoyl-L-aspartate

N-carbamoylsarcosine

D-glutamate

3-phospho-L-serine

N-acetyl-L-methionine

N-acetyl-L-glutamate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

pyruvate

5-chloro-4-hydroxy-2-oxopentanoate

2-oxobutanoate

2-oxoglutarate

chorismate

succinate

fumarate

(S)-malate

D-glucarate

D-threo-isocitrate

(S)-lactate

(R)-glycerate

acetate

formate

propanoate

butanoate

octanoate

decanoate

(2E,6E)-farnesoate

(15Z)-tetracosenoate

oleate

linoleate

α-linolenate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

phytenate

palmitate

fluoroacetate

5-chloro-5-deoxy-D-ribonate

6-methoxy-2-all-trans-octaprenyl-1,4-benzoquinone

3-methyl-6-methoxy-2-octaprenyl-1,4-benzoquinone

diacetyl

glycolaldehyde

fluoroacetaldehyde

(2E,6E)-farnesal

D-glyceraldehyde

formaldehyde

isobutanal

1-octanal

acetaldehyde

phytenal

glycerol

di-trans,octa-cis-undecaprenyl phosphate

geranylgeranyl diphosphate

all-trans-nonaprenyl diphosphate

all-trans-octaprenyl diphosphate

all-trans-hexaprenyl diphosphate

all-trans-heptaprenyl diphosphate

all-trans-decaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

3-nonaprenyl-4-hydroxybenzoate

3-heptaprenyl-4-hydroxybenzoate

3-decaprenyl-4-hydroxybenzoate

3-octaprenyl-4-hydroxybenzoate

N-acetyl-α-D-mannosamine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

GDP-α-D-mannose

ADP ribose 1'',2''-cyclic phosphate

ADP ribose 1''-phosphate

ADP-D-ribose

D-glyceraldehyde 3-phosphate

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-fructofuranose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-mannopyranose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

D-ribulose 5-phosphate

aldehydo-D-ribose 5-phosphate

α-D-ribose-1-phosphate

5-fluoro-5-deoxy-D-ribose 1-phosphate

2-deoxy-α-D-ribose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

5'-chloro-5'-deoxyadenosine

5-chloro-5-deoxyribose 1-phosphate

cyclic-AMP

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-ATP

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-AMP

P¹,P⁴-bis(5'-adenosyl) tetraphosphate

5'-deoxy-5'-fluoroadenosine

2-iminosuccinate

N-acetyl-L-glutaminyl-L-glutamine

N-acetyl-L-glutaminyl-L-glutamine amide

D-alanyl-D-alanine

cobalt-factor III

cob(I)yrinate a,c-diamide

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

Mg-protoporphyrin

cob(II)yrinate c-monoamide

cob(II)yrinate a,c-diamide

adenosyl-cobinamide phosphate

adenosylcobinamide-GDP

adenosylcobalamin 5'-phosphate

cobalt-sirohydrochlorin

N₂

uroporphyrinogen-I

protoporphyrin IX

uroporphyrinogen-III

siroheme

oxygen

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

5,10-methenyltetrahydrofolate mono-L-glutamate

2-octaprenylphenol

dimethyl sulfide

3-dimethylsulfoniopropionaldehyde

L-cysteate

3-sulfopyruvate

(2R)-3-sulfolactate

trimethyl sulfonium

selenide

hydrogencarbonate

phosphate

triphosphate

diphosphate

ammonium

H⁺

Co²⁺

Mg²⁺

Fe²⁺

dehydrospermidine

putrescine

spermidine

acetamide

phosphoribulosylformimino-AICAR-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

methane

(25S)-3-oxocholest-4-en-26-oate

(25S)-3-oxocholest-4-en-26-oyl-CoA

(indol-3-yl)acetate