an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

3-ureidopropanoate

coproporphyrinogen III

1-deoxy-L-glycero-tetrulose 4-phosphate

3-dehydroquinate

3-dehydroshikimate

2-phosphoglycolate

glycolate

α-D-glucosamine 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

(R)-1-amino-2-propanol O-2-phosphate

(R)-1-aminopropan-2-ol

α-ribazole

α-ribazole 5'-phosphate

thiamine diphosphate

5-oxo-L-proline

β-D-ribosylnicotinate

L-histidinol phosphate

4'-phosphopantetheine

(R)-4'-phosphopantothenoyl-L-cysteine

(R)-4'-phosphopantothenate

(R)-pantothenate

histidinal

histidinol

oxalosuccinate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

5-phospho-β-D-ribosylamine

γ-L-glutamyl 5-phosphate

glutathione disulfide

adenosine 5'-phosphosulfate

adenosine 5'-phosphoselenate

(indol-3-yl)pyruvate

(indol-3 yl)acetyl-CoA

(R)-2,3-dihydroxy-3-methylpentanoate

(S)-2-aceto-2-hydroxybutanoate

5-deoxy-α-ribose 1-phosphate

S-methyl-5'-thioadenosine

S-methyl-5-thio-α-D-ribose 1-phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

thiamine phosphate

O-ureido-L-homoserine

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

prephenate

shikimate

shikimate 3-phosphate

CDP-glycerol

5-amino-6-(D-ribitylamino)uracil

carbon monoxide

carbamoyl phosphate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

pseudouridine 5'-phosphate

orotidine 5'-phosphate

5-enolpyruvoyl-shikimate 3-phosphate

(S)-2,3,4,5-tetrahydrodipicolinate

(S)-2-acetolactate

canavaninosuccinate

L-canavanine

L-arginino-succinate

glycerone phosphate

H₂

hydrogenobyrinate

hydrogenobyrinate a,c-diamide

L-β-lysine

(S)-4-amino-5-oxopentanoate

5-aminolevulinate

porphobilinogen

preuroporphyrinogen

5-carboxymethyl-2-hydroxymuconate

5-amino-6-(5-phospho-D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

N-(5-phosphoribosyl)-anthranilate

anthranilate

3-phosphooxypyruvate

(R)-mevalonate

(R)-5-phosphomevalonate

isopentenyl diphosphate

prenyl diphosphate

D-erythro-imidazole-glycerol-phosphate

imidazole acetol-phosphate

N-acetyl-L-glutamate 5-semialdehyde

N-acetylglutamyl-phosphate

citrate

(S)-3-methyl-2-oxopentanoate

urea

hexulose 6-phosphate

N¹-(5-phospho-β-D-ribosyl)glycinamide

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

nicotinate adenine dinucleotide

3-methyl-2-oxobutanoate

coenzyme B

methanophenazine

CoB-CoM heterodisulfide

dihydromethanophenazine

(2S)-2-isopropylmalate

2-isopropylmaleate

(2R,3S)-3-isopropylmalate

(2S)-2-isopropyl-3-oxosuccinate

4-methyl-2-oxopentanoate

3-ethylmalate

2-oxovalerate

propionamide

(indol-3-yl)acetamide

acrylamide

acrylate

4-guanidinobutyramide

4-guanidinobutanoate

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

oxaloacetate

β-nicotinate D-ribonucleotide

quinolinate

phosphoenolpyruvate

hydrogen peroxide

H₂O

CO₂

2-carboxy-L-threo-pentonate

2-carboxy-L-xylonolactone

2,3-dioxo-L-gulonate

cyclic- 3,4-O-oxalyl-L-threonate

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

bisorganyltrisulfane

dehydroascorbate (bicyclic form)

cyclic-2,3-O-oxalyl-L-threonate

enol-phenylpyruvate

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

ammonia

L-dehydro-ascorbate

4-(β-D-ribofuranosyl)-N-succinylaminobenzene 5'-phosphate

4-(β-D-ribofuranosyl)hydroxybenzene 5'-phosphate

α-D-galacturonate 1-phosphate

L-xylo-hex-3-ulono-1,4-lactone

L-gulono-1,4-lactone

2-(α-hydroxyethyl)thiamine diphosphate

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

sulfoethylcysteine

2-(sulfomethyl)thiazolidine-4-carboxylate

(2R,3S)-3-methylmalate

citraconate

4-amino-2-methyl-5-pyrimidinemethanol

dialurate

enolaldehyde

acetyl phosphate

(R)-mevalonate diphosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl 5-phosphate]-D-ribitol

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-5-[1-α -D- ribofuranosyl triphosphate]-D-ribitol

S-ribosyl-L-homocysteine

autoinducer 2

31-O-desmethylFK-506

FK-506

3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA

N²-succinyl-L-glutamate 5-semialdehyde

4-acetamidobutanal

4-acetamidobutanoate

2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

(L-threonylcarbamoyl)adenylate

5,6-dimethylbenzimidazole

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

N²-succinylglutamate

4-(β-D-ribofuranosyl)aminobenzene-5'-phosphate

(S)-dihydroorotate

isopentenyl phosphate

oxalate

coenzyme F₃₉₀-A

7,8-didemethyl-8-hydroxy-5-deazariboflavin

(2S)-lactyl-2-diphospho-5'-guanosine

DNA without lesion

(2E,6E)-farnesyl diphosphate

2-iminosuccinate

DNA with lesion

phenylacetate

adenosylcobalamin

cobalt-precorrin-5B

cobalt-precorrin-6A

adenosylcobinamide

adenosylcobalamin 5'-phosphate

adenosyl-cobinamide phosphate

adenosylcobinamide-GDP

Mg-protoporphyrin

cob(II)yrinate a,c-diamide

cobalt-precorrin-2

cobalt-precorrin-3

cobalt-sirohydrochlorin

cobalt-factor III

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobyrate

cobalt-precorrin-7

cobalt-precorrin-8

cobalt-precorrin-6B

cobalt-precorrin-4

cob(I)yrinate a,c-diamide

cob(II)yrinate c-monoamide

cobyrinate

cobalt-precorrin-5A

N₂

hydrogen cyanide

protoporphyrinogen IX

uroporphyrinogen-III

protoporphyrin IX

uroporphyrinogen-I

coproporphyrinogen I

siroheme

S⁰

hydrogen sulfide

oxygen

2-chloroacetate

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

2-O-(α-D-mannosyl)-3-phospho-D-glycerate

2-O-(α-D-mannosyl)-D-glycerate

3-phospho-D-glyceroyl-phosphate

2,3-diphospho-D-glycerate

3-phospho-D-glycerate

2-phospho-D-glycerate

(2S)-2-phospholactate

(2R)-2,3-dihydroxy-3-methylbutanoate

(R)-citramalate

5,10-methenyltetrahydrofolate mono-L-glutamate

3-(all-trans-octaprenyl)benzene-1,2-diol

2-octaprenylphenol

(S)-2-hydroxyglutarate

monodehydroascorbate radical

S-(hydroxymethyl)glutathione

dimethyl sulfide

glutathione

thiocyanate

methanethiol

S-sulfanylglutathione

5-(2-hydroxyethyl)-4-methylthiazole

4-methyl-5-(2-phosphooxyethyl)thiazole

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

L-cysteate

3-sulfopyruvate

sulfoacetaldehyde

coenzyme M

trimethyl sulfonium

sulfate

sulfite

selenite

selenate

thiosulfate

nitrate

hydrogensulfite

hydrogencarbonate

molybdate

chloride

phosphate

diphosphate

triphosphate

Fe³⁺

ammonium

H⁺

Mo²⁺

Fe²⁺

Co²⁺

Mg²⁺

Cu²⁺

glycine betaine

agmatine

putrescine

dehydrospermidine

spermidine

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

acetamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

methane

(indol-3-yl)acetate

succinyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

phenylacetyl-CoA

isobutanoyl-CoA

acetyl-CoA

3'-dephospho-CoA

4-hydroxybenzoyl-CoA

propanoyl-CoA

acetoacetyl-CoA

L-galactono-1,4-lactone

FMN

FAD

FMNH₂

(S)-NADHX

(R)-NADHX

NADPH

NADH

NADP⁺

NAD⁺

caldariellaquinol

caldariellaquinone

N,N-dimethylglycine

L-homocysteine

methyl-CoM

coenzyme A

tetrahydrosarcinapterin

5-methyl-tetrahydrosarcinapterin

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

oxidized coenzyme F₄₂₀-2

oxidized coenzyme F₄₂₀-0

5,10-methenyltetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

tetrahydromethanopterin

5-formyl-tetrahydromethanopterin

demethylated 7,8-dihydromethanopterin

7,8-dihydromethanopterin

5,10-methylene-tetrahydromethanopterin

5,6,7,8-tetrahydrofolate

tetrahydropteroyl tri-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

7,8-dihydrofolate monoglutamate

riboflavin

L-ascorbate

nicotinate

menadione

(S)-1-pyrroline-5-carboxylate

precorrin-1

precorrin-2

precorrin-3B

precorrin-4

precorrin-5

precorrin-7

precorrin-8x

precorrin-6B

precorrin-6A

precorrin-3A

sirohydrochlorin

hydantoin

6,7-dimethyl-8-(1-D-ribityl)lumazine

reduced riboflavin

7,8-dihydroneopterin 3'-triphosphate

7,8-dihydroneopterin 2',3'-cyclic phosphate

(7,8-dihydropterin-6-yl)methyl diphosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

2-amino-6-[1-hydroxyethyl]-7-methyl-7,8-dihydropterin

7,8-dihydroneopterin 2'-phosphate

7,8-dihydroneopterin 3'-phosphate

7,8-dihydroneopterin

6-(hydroxymethyl)-7,8-dihydropterin

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol 5'-phosphate

[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-(4-aminophenyl)-1-deoxy-D-ribitol

7,8-dihydropterin-6-ylmethyl-4-(β-D-ribofuranosyl)aminobenzene 5'-phosphate

7,8-dihydropteroate

adenine

2'-deoxyadenosine

2'-deoxyguanosine

xanthosine

adenosine

inosine

guanosine

dAMP

dGMP

dITP

dGTP

dATP

dIDP

dGDP

dADP

IDP

GDP

ADP

IMP

XMP

GMP

AMP

ITP

GTP

ATP

5,6-dihydrouracil

5,6-dihydrothymine

uridine 3'-monophosphate

cytidine-3'-monophosphate

orotate

dUMP

dUDP

dUTP

dTTP

dCTP

uracil

dCMP

dCDP

UDP

UTP

dTMP

dTDP

CTP

CDP

UDP-α-D-galactose

UDP-α-D-glucose

UDP-α-D-glucuronate

UDP-α-D-galacturonate

UDP-N-acetyl-α-D-glucosamine

cytidine

uridine

thymidine

2'-deoxycytidine

2'-deoxyuridine

thymine

CMP

UMP

(indole-3-yl)acetonitrile

salicylaldehyde

4-hydroxybenzoate

benzaldehyde

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

menadiol

salicylate

4-aminobenzoate

benzoate

L-α-amino-ε-keto-pimelate

L-serine

β-alanine

L-proline

L-alanine

L-glutamine

L-leucine

glycine

L-glutamate

L-histidine

L-arginine

L-lysine

L-aspartate

L-threonine

L-tyrosine

L-cysteine

L-tryptophan

L-phenylalanine

D-alanine

L-aspartyl-4-phosphate

sarcosine

N-carbamoylglycine

N-acetyl-L-aspartate

N-acetyl-L-ornithine

N-acetyl-L-methionine

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

O-acetyl-L-homoserine

L-threonine 3-O-phosphate

3-phospho-L-serine

L-citrulline

L-valine

L-isoleucine

L-homoserine

L-glutamate-5-semialdehyde

L-aspartate 4-semialdehyde

L-ornithine

O-phospho-L-homoserine

S-adenosyl-L-methionine

S-adenosyl-L-homocysteine

meso-diaminopimelate

L-methionine

L,L-diaminopimelate

chorismate

succinate

fumarate

(S)-malate

3-(carbamoylamino)-2-methylpropanoate

(3E,5R)-5-carboxy-2-oxohept-3-enedioate

cis-aconitate

D-threo-isocitrate

(R)-lactate

(S)-lactate

pyruvate

acetate

formate

propanoate

octanoate

apo-4'-lycopenoate

(R)-pantoate

aldehydo-D-glucuronate

aldehydo-D-galacturonate

3-(4-hydroxyphenyl)pyruvate

3-phenyl-2-oxopropanoate

2-oxobutanoate

2-oxoglutarate

methylglyoxal

diacetyl

(R)-acetoin

glycolaldehyde

hydroxypyruvaldehyde phosphate

formaldehyde

acetaldehyde

1-octanal

(S)-lactaldehyde

(R)-lactaldehyde

D-glyceraldehyde

α-D-glucopyranose

β-D-glucopyranose

methanol

ethanol

(3R)-linalool

(3S)-linalool

myo-inositol

1D-myo-inositol 2-monophosphate

1D-myo-inositol 1-monophosphate

1D-myo-inositol 6-monophosphate

1D-myo-inositol 5-monophosphate

1D-myo-inositol 4-monophosphate

1D-myo-inositol 3-monophosphate

saturated CDP-archaeol

unsaturated CDP-archaeol

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

geranyl diphosphate

geranylgeranyl diphosphate

all-trans-octaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

apo-4'-lycopenal

phytyl diphosphate

3-octaprenyl-4-hydroxybenzoate

1-(β-D ribofuranosyl)nicotinamide

maltotriose

maltotetraose

maltopentaose

maltohexaose

sucrose

keto-D-fructose

N-acetyl-α-D-glucosamine 1-phosphate

β-D-fructofuranose

D-ribulose-1,5-bisphosphate

sucrose 6^F-phosphate

GDP-α-D-mannose

GDP-4-dehydro-α-D-rhamnose

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-erythrose 4-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

6-deoxy-5-ketofructose 1-phosphate

α-D-mannopyranose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

D-ribulose 5-phosphate

2-deoxy-α-D-ribose 1-phosphate

α-D-galactose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 1-phosphate

α-D-mannose 1-phosphate

aldehydo-L-galactonate

L-gulonate

adenosine 3'-monophosphate

guanosine 3'-monophosphate

5'-deoxyadenosine

adenylo-succinate

1-(5-phospho-β-D-ribosyl)-ATP

1-(5-phospho-β-D-ribosyl)-AMP

cyclic-AMP

β-nicotinamide D-ribonucleotide