an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

H₂O

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

3-dehydroshikimate

shikimate

γ-L-glutamyl 5-phosphate

nicotinate adenine dinucleotide

formamide

CO₂

orotidine 5'-phosphate

xanthine

2-C-methyl-D-erythritol 4-phosphate

2-C-methyl-D-erythritol-2,4-cyclodiphosphate

(R)-4'-phosphopantothenoyl-L-cysteine

(R)-4'-phosphopantothenate

4'-phosphopantetheine

thiamine diphosphate

acetyl phosphate

isopentenyl diphosphate

(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

phosphoenolpyruvate

glycerone phosphate

α-D-glucosamine 1-phosphate

carbamoyl phosphate

prenyl diphosphate

1-piperideine 6-carboxylate

4-oxoglutaramate

quinolinate

pyruvic oxime

β-nicotinate D-ribonucleotide

ammonia

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

enol-phenylpyruvate

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

dethiobiotin

7,8-diaminopelargonate

S-adenosyl-4-methylsulfanyl-2-oxobutanoate

8-amino-7-oxononanoate

urocanate

4-imidazolone-5-propanoate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

O-acetyl-L-serine

hydrogen selenide

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

N¹-(5-phospho-β-D-ribosyl)glycinamide

5-phospho-β-D-ribosylamine

coproporphyrinogen III

hydrogen peroxide

5-enolpyruvoyl-shikimate 3-phosphate

shikimate 3-phosphate

oxaloacetate

5-amino-6-(D-ribitylamino)uracil

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-amino-6-(5-phospho-D-ribitylamino)uracil

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

dihydroxyacetone

4-pyridoxolactone

(E)-glutaconate

3-dehydroquinate

H₂

2-oleoylglycerol

N-acetyl-β-D-glucosamine-1,6-anhydro-N-acetyl-β-D-muramate

DNA without lesion

(S)-dihydroorotate

4-guanidinobutyramide

(indol-3-yl)acetamide

4-guanidinobutanoate

propionamide

acrylate

acrylamide

(R)-1-amino-2-propanol O-2-phosphate

(E)-4-coumaroyl-CoA

3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA

2,3-didehydroadipyl-CoA

2-carboxymethyl-3-hydroxyphenylpropanoyl-CoA

(E)-2-benzylidenesuccinyl-CoA

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

β-D-ribosylnicotinate

hydroxylamine

4-(2'-carboxyphenyl)-4-oxobutyryl-CoA

2-succinylbenzoate

3-methyl-2-oxobutanoate

glycolate

2-phosphoglycolate

1-deoxy-L-glycero-tetrulose 4-phosphate

S-Inosyl-L-homocysteine

S-methyl-5'-thioinosine

S-methyl-5'-thioadenosine

3-phosphooxypyruvate

nigerose

urea

L-canavanine

butanoyl phosphate

gallate

1,2,3,5-tetrahydroxybenzene

pyrogallol

phloroglucinol

dihydrophloroglucinol

3-hydroxy-5-oxohexanoate

3-hydroxy-5- oxohexanoyl-CoA

succinate semialdehyde

4-aminobutanoate

5-ureidoimidazole-4-carboxylate

5-aminoimidazole-4-carboxylate

4-aminoimidazole

3,5-dihydro-4H-imidazol-4-one

(S)-3-methyl-2-oxopentanoate

L-arginino-succinate

autoinducer 2

S-ribosyl-L-homocysteine

S-methyl-5-thio-α-D-ribose 1-phosphate

isochorismate

(1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate

2-succinyl-5-enolpyruvoyl-6-hydroxy-3-cyclohexene-1-carboxylate

1,4-dihydroxy-2-naphthoate

1,4-dihydroxy-2-naphthoyl-CoA

2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA

2-oxepin-2(3H)-ylideneacetyl-CoA

3-oxo-5,6-didehydrosuberyl-CoA

3-oxo-5,6-didehydrosuberyl-CoA semialdehyde

N-acetyl-D-muramate 6-phosphate

1,6-anhydro-N-acetyl-β-muramate

N⁵-carboxyaminoimidazole ribonucleotide

(S)-2-amino-6-oxohexanoate

2-amino-3-carboxymuconate-6-semialdehyde

2-iminoacetate

(2E,6E)-farnesyl diphosphate

2-iminopropanoate

2-iminosuccinate

D-alanyl-D-alanine

L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

L-alanyl-γ-D-glutamyl-meso-diaminopimelate

L-citrulline

L-glutamate

L-threonine

L-serine

L-histidine

L-asparagine

L-leucine

glycine

L-glutamine

L-aspartate

L-phenylalanine

L-arginine

L-lysine

L-isoleucine

L-alanine

L-tyrosine

L-proline

L-valine

L-methionine

L-cysteine

L-ornithine

O-phospho-L-homoserine

L-homoserine

L-glutamate-5-semialdehyde

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

L-aspartate 4-semialdehyde

S-sulfo-L-cysteine

L-homocysteine

L-canaline

meso-diaminopimelate

L-selenocysteine

L-isoglutamine

L-aspartyl-4-phosphate

formyl-L-isoglutamine

N-acetyl-L-ornithine

N-formimino-L-glutamate

N-carbamoyl-L-aspartate

L-threonine 3-O-phosphate

3-phospho-L-serine

N-formimino-glycine

N-acetyl-L-glutamate

N-acetyl-L-methionine

D-glutamate

D-alanine

D-aspartate

(S)-3-amino-2-methylpropanoate

adenosine 2',3'-cyclic monophosphate

guanosine 2',3'-cyclic monophosphate

ADP

ATP

hypoxanthine

2'-deoxyinosine

5-chloro-5-deoxyribose 1-phosphate

5'-chloro-5'-deoxyadenosine

2'-deoxyadenosine

2'-deoxyguanosine

XMP

IMP

GDP

GMP

pppGpp

GTP

ppGpp

dGDP

dGTP

dADP

dATP

5'-deoxyadenosine

guanosine 3'-monophosphate

adenosine 3'-monophosphate

cyclic-AMP

AMP

ITP

dIMP

dITP

XTP

adenylo-succinate

adenine

guanine

purine

uracil

thymine

preQ₁

uridine 2'3'-cyclic monophosphate

cytidine 2',3'-cyclic monophosphate

dCDP

dTDP

dUDP

dUTP

dCTP

dTTP

dCMP

dTMP

dUMP

2-methylsulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

2-sulfanyl-N⁶-dimethylallyladenosine³⁷ in tRNA

β-nicotinamide D-ribonucleotide

UMP

CMP

CDP

UDP

CTP

UTP

NADPH

NADH

NADP⁺

NAD⁺

cytidine-3'-monophosphate

uridine 3'-monophosphate

UDP-α-D-glucose

UDP-N-acetyl-α-D-mannosamine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-D-glutamate

UDP-N-acetyl-α-D-muramoyl-L-alanine

UDP-N-acetyl-α-D-muramate

UDP-N-acetyl-α-D-glucosamine-enolpyruvate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysine

UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

UDP-N-acetyl-α-D-mannosaminuronate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate

UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

UDP-N-acetyl-α-D-glucosamine

ADP-D-ribose

4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

inosine

xanthosine

guanosine

adenosine

2'-deoxyuridine

2'-deoxycytidine

thymidine

uridine

cytidine

5'-deoxy-5'-fluoroadenosine

precorrin-1

precorrin-2

sirohydrochlorin

orotate

(S)-1-pyrroline-5-carboxylate

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydropteroate

7,8-dihydrofolate monoglutamate

5,6,7,8-tetrahydrofolate

tetrahydropteroyl tri-L-glutamate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

6,7-dimethyl-8-(1-D-ribityl)lumazine

FMNH₂

reduced riboflavin

FADH₂

FAD

FMN

riboflavin

urate

6,8-dihydroxypurine

8-hydroxypurine

protocatechuate

4-methylphenol

4-aminobenzoate

(3R)-hydroxy, 6-trans-tridecenoyl-CoA

2-trans-6-trans-tridecadienoyl-CoA

(3R)-hydroxy- 5-cis, 7-trans-tetradecadienoyl-CoA

2-trans, 5-cis, 7-trans-tetradecatrienoyl-CoA

(3R)-hydroxy-nonanoyl-CoA

2-trans-nonenoyl-CoA

(3R)-hydroxy-undecanoyl-CoA

(3E)-undec-2-enoyl-CoA

(3R)-hydroxy, 4-trans-undecenoyl-CoA

2-trans, 4-trans-undecadienoyl-CoA

(3R)-hydroxy, 6-cis-tridecenoyl-CoA

2-trans,6-cis-tridecadienoyl-CoA

(3R)-hydroxy-5-trans-dodecenoyl-CoA

(2E,5E)-dodeca-2,5-dienoyl-CoA

(3E,5Z)-tetradeca-3,5-dienoyl-CoA

di-trans,octa-cis-undecaprenyl phosphate

trans,octacis-decaprenyl phosphate

geranyl diphosphate

all-trans-heptaprenyl diphosphate

geranylgeranyl diphosphate

mono-trans,octa-cis-decaprenyl diphosphate

di-trans,octa-cis-undecaprenyl diphosphate

(3S)-linalool

(3R)-linalool

1-oleoyl-2-lyso-glycerone phosphate

1-oleoyl-sn-glycerol 3-phosphate

1-oleoyl-2-palmitoyl-phosphatidylglycerol

dioleoyl phosphatidate

phosphatidylglycerophosphate (1-octadecenoyl(9Z), 2-palmitoyl)

nisin

ferrichrome

acetyl-CoA

3'-dephospho-CoA

malonyl-CoA

(3R,11Z,14Z,17Z)-3-hydroxyicosatrienoyl-CoA

(11Z,14Z,17Z)-3-oxoicosatrienoyl-CoA

(E)-glutaconyl-CoA

(R)-2-hydroxyglutaryl-CoA

(E)-2-methylcrotonoyl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-hexa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyhexanoyl)-CoA

3-hydroxyisovaleryl-CoA

(3S)-hydroxyadipyl-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-buta-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxybutanoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(E-octa-2-enoyl)-CoA

3-oxo-2-(cis-2'-pentenyl)-cyclopentane-1-(3R-hydroxyoctanoyl)-CoA

(2E,5Z)-tetradecenoyl-CoA

methylacrylyl-CoA

(+)-7-epi-jasmonoyl-CoA

dihomo γ-linolenoyl-CoA

isobutanoyl-CoA

4-hydroxybutanoyl-CoA

2-methylacetoacetyl-CoA

succinyl-CoA

2-methylbutanoyl-CoA

phenylacetyl-CoA

(S)-3-hydroxy-isobutanoyl-CoA

oleoyl-CoA

decanoyl-CoA

octanoyl-CoA

palmitoyl-CoA

stearoyl-CoA

propanoyl-CoA

butanoyl-CoA

(S)-3-hydroxydecanoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(S)-3-hydroxyoctanoyl-CoA

(S)-3-hydroxy-(5Z)-tetradecenoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

(3R)-3-hydroxyoctadecanoyl-CoA

3-oxoadipyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

3-oxodecanoyl-CoA

(2E)-dec-2-enoyl-CoA

(2E)-oct-2-enoyl-CoA

(2E)-octadec-2-enoyl-CoA

crotonyl-CoA

1-(β-D ribofuranosyl)nicotinamide

cellotetraose

β-D-cellobiose

sucrose

aldehydo-D-ribose

β-D-ribofuranose

α-D-ribofuranose

β-D-glucopyranose

α-D-glucopyranose

β-D-fructofuranose

N-acetylmuramate

N-acetyl-α-D-muramoyl-L-alanine(1-)

N-acetyl-β-D-glucosamine

N-acetyl-α-D-glucosamine 1-phosphate

glycerol

decaprenyl-diphospho-N-acetylmuramoyl-pentapeptide

5-phospho-α-D-ribose 1-diphosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

α-D-ribose-1-phosphate

5-fluoro-5-deoxy-D-ribose 1-phosphate

2-deoxy-α-D-ribose 1-phosphate

D-xylulose 5-phosphate

1-deoxy-D-xylulose 5-phosphate

D-ribulose 5-phosphate

α-D-glucopyranose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 6-phosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

α-D-glucose 6-phosphate

β-D-glucose 6-phosphate

D-glyceraldehyde 3-phosphate

undecaprenyldiphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine

undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-L-lysyl- D-alanine

a peptidoglycan dimer (E. faecium, tetrapeptide)

a peptidoglycan dimer (E. faeciums)

a peptidoglycan dimer (S. aureus)

a peptidoglycan dimer (mycobacteria)

decaprenyl-pyrophosphoryl-(N-acetylglucosamine)-N-acetylmuramyl-(pentapeptide)

a peptidoglycan tetramer with a D,D cross-link (Enterococcus faecium)

a peptidoglycan with D,D cross-link (S. aureus)

a peptidoglycan tetramer with an L,D cross-link (Enterococcus faecium)

a peptidoglycan with L,D cross-links (mycobacteria)

a peptidoglycan with D,D cross-links (mycobacteria)

a peptidoglycan dimer (meso-diaminopimelate containing)

a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-(glycyl)₅-D-alanyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanine

ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparatyl)-L-lysyl-D-alanine

GlcNAc-1,6-anhMurNAc-L-Ala-γ-D-Glu-DAP-D-Ala

sucrose 6^F-phosphate

acetaldehyde

butan-1-al

acetate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

(3E,5Z)-tetradecadienoate

palmitate

stearate

di-homo-γ-linolenate

decanoate

butanoate

pyruvate

glyoxylate

2-oxobutanoate

2-oxoglutarate

3-phenyl-2-oxopropanoate

formate

propanoate

(R)-lactate

(S)-lactate

4-hydroxybutanoate

(R)-2-hydroxyglutarate

chorismate

succinate

fumarate

nicotinamide

5-amino-4-imidazolecarboxyamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

acetamide

(+)-7-epi-jasmonate

(indol-3-yl)acetate

phenylacetate

myo-inositol

1D-myo-inositol 3-monophosphate

butan-1-ol

agmatine

putrescine

cadaverine

spermidine

2-aminoprop-2-enoate

dimethyl sulfide

glutathione

3-sulfopyruvate

L-cysteate

(R)-S-lactoylglutathione

trimethyl sulfonium

thiosulfate

hydrogencarbonate

superoxide

phosphonate

phosphate

diphosphate

Zn²⁺

Co²⁺

Fe²⁺

Cd²⁺

Cu²⁺

Ca²⁺

ammonium

Na⁺

H⁺

thiamine

nicotinate

pyridoxal

(R)-NADHX

(S)-NADHX

coenzyme A

preQ₀

(S)-3-hydroxy-isobutanoate

5,10-methenyltetrahydrofolate mono-L-glutamate

(R)-methylmalonate-semialdehyde

(S)-methylmalonate-semialdehyde

3-phospho-D-glyceroyl-phosphate

2-phospho-D-glycerate

3-phospho-D-glycerate

sn-glycerol 3-phosphate

hydrogen sulfide

oxygen

protoporphyrinogen IX

uroporphyrinogen-III

protoporphyrin IX

siroheme

protoheme

DNA with lesion