Escherichia coli DPD4193
Ancestors
Genotype with respect to parental
aroH367 tyrR366 tna-2 lacY5 malT384 aroG397fbr trpE382 Ptrc-tyrA::kanR ΔpheLA
Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | aroH367 tyrR366 tna-2 lacY5 malT384 aroG397fbr trpE382 Ptrc-tyrA::kanR ΔpheLABars (|) indicate differences between strains.
Modifications
| Gene | Organism | Modification |
|---|---|---|
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Silencing
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Silencing
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Silencing
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Silencing
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Feedback insensitive
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Overexpression
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Silencing
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Silencing
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Feedback insensitive
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Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| L-tyrosine | Titer | 0.18 g/L | Flask | [244] | |||
| L-tyrosine | Titer | 55.0 g/L | Fed-Batch | [244] | |||
| L-tyrosine | Substrate yield | 0.09 g/g of sustrate | Flask | [244] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.