Escherichia coli HS

Ancestors
Derived strains

Genotype with respect to parental

ΔJIB* ΔthrB ΔmetA ΔlysA ΔiclR ΔptsG ΔgalR ΔlacI::Ptrc-rhtA Ptrc-rhtA Ptrc-eamA Ptrc-metL Ptrc-thrA Ptrc-glk Ptrc-gltB


Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | ΔJIB* ΔthrB ΔmetA ΔlysA ΔiclR ΔptsG ΔgalR ΔlacI::Ptrc-rhtA Ptrc-rhtA Ptrc-eamA Ptrc-metL Ptrc-thrA Ptrc-glk Ptrc-gltB

Bars (|) indicate differences between strains.


Modifications
Gene Organism Modification
Silencing
Silencing
Silencing
Silencing
Silencing
Silencing
Silencing
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
glk
Overexpression
Overexpression

Production
Metabolites Heterologous Production type Production Biomass Carbon source Time Scale Ref.
L-homoserine Titer 7.31 g/L * 11.61 OD600* Glucose Flask [ 255 ]
L-homoserine Titer 13.39 g/L * Glucose Flask [ 255 ]
L-homoserine Titer 13.39 g/L * 13.29 OD600* Glucose Flask [ 255 ]

* Inferred from plots using RetroPlot.


References