Escherichia coli LEU23
Ancestors
Derived strains
Genotype with respect to parental
ΔldhA
Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | ΔlacI | ycjV::Ptrc-leuAfbrEc | yciQ::Ptrc-leuAfbrEc | yghE::Ptrc-leuAfbrEc | yjgX::Ptrc-leuBCD | yjiT::Ptrc-ilvIHfbr | ylbE::Ptrc-ilvIHfbr | yjiV::Ptrc-ilvEDC | PleuA::Ptrc | ΔlivK | livJ::Ptrc-azlC | brnQ::Ptrc-brnFE | yjiP::pntAB | ilvE::Ptrc-Bcldh | ΔpoxB | ΔpflB | ΔldhABars (|) indicate differences between strains.
Modifications
| Gene | Organism | Modification |
|---|---|---|
|
Silencing
|
Production
| Metabolites | Heterologous | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|---|
| L-leucine | Titer | 54.6 g/L | 99.5 OD600* | Glucose | 48 h * | Fed-Batch | [ 265 ] | |
| L-leucine | Substrate yield | 0.17 g/g of sustrate | 99.5 OD600* | Glucose | 48 h * | Fed-Batch | [ 265 ] | |
| L-leucine | Titer | 17.15 g/L * | 37.81 OD600* | Glucose | Flask | [ 265 ] | ||
| L-leucine | Substrate yield | 0.14 g/g of sustrate * | 37.81 OD600* | Glucose | Flask | [ 265 ] |
* Inferred from plots using RetroPlot.