Escherichia coli HGA1

Ancestors
Derived strains

Genotype with respect to parental

ΔtyrR, pheA and trpE


Genotype with respect to wild type
F+ (λ) | l-Tyriosine auxotrophic | ΔtyrR, pheA and trpE | Plasmid pAP11 added

Bars (|) indicate differences between strains.


Plasmids
  • pAP11 (pAP with aroGfbr, tyrAfbr, tktA and ppsA, p15A ori with PRPL)


Strain derived from a randomly mutated strain.


Modifications
Gene Organism Modification
Silencing
Silencing
Silencing

Production
Metabolites Production type Production Biomass Carbon source Time Scale Ref.
L-tyrosine Titer 4.22 g/L 48 h * Flask [268]

* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.

References