Escherichia coli HGA4
Ancestors
Genotype with respect to parental
ΔtyrR, pheA and trpE
Genotype with respect to wild type
F+ (λ) | l-Tyriosine auxotrophic | ΔtyrR, pheA and trpE | Plasmid pAP12 addedBars (|) indicate differences between strains.
Plasmids
-
pAP12 (pAP with aroGfbr, tyrAfbr and aroABC, p15A ori with PRPL)
Strain derived from a randomly mutated strain.
Modifications
| Gene | Organism | Modification |
|---|---|---|
|
Silencing
|
||
|
Silencing
|
||
|
Silencing
|
Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| L-tyrosine | Titer | 3.7 g/L * | 48 h * | Flask | [268] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.