Escherichia coli KW022

Ancestors

Genotype with respect to parental

Δpta


Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | Plasmid PH5a1 added | ΔtrpR ΔtrpL | ΔpykF | ΔptsH | M1-37::galP | M1-93::glk | Δpta

Bars (|) indicate differences between strains.


Plasmids

Strain derived from a randomly mutated strain.


Modifications
Gene Organism Modification
pta
Silencing

Production
Metabolites Production type Production Biomass Carbon source Time Scale Ref.
L-tryptophan Titer 21.6 g/L Fed-Batch [135]
L-tryptophan Substrate yield 0.135 g/g of sustrate 24 h Fed-Batch [135]
acetate Titer 0.5 g/L Fed-Batch [135]

* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.

References