Silencing
Overexpression
Feedback insensitive
Attenuation
Feed-forward insensitive
Inhibition insensitive
Unstated
Combined modifications

Titer in Flask for L-(-)-3-Phenyllactic acid

Modifications
Strain Maximum production tyrA tyrB ppr trpE ptsH ptsI crr glf glk aroG pheA tktA pck ghrB pprA ldhL fdh
E. coli CGSC4510 28 mg/L
E. coli MG-P2 189 mg/L
E. coli MG-P3 212 mg/L
E. coli MG-P1 251 mg/L
E. coli MG-P4 417 mg/L
E. coli MP-P5 578 mg/L
E. coli MG-P6 717.4 mg/L
E. coli MG-P7 880 mg/L
E. coli MG-P8 1,140 mg/L
E. coli MG-P9 1,210 mg/L
E. coli MG-P10 1,420 mg/L
E. coli BL21(pETDuet-ldhL-fdh) 13,227.132 mg/L

Titer in Fed-Batch for L-(-)-3-Phenyllactic acid

Modifications
Strain Maximum production tyrA tyrB ppr trpE ptsH ptsI crr glf glk aroG pheA tktA pck
E. coli MG-P10 52,890 mg/L

Substrate yield in Fed-Batch for L-(-)-3-Phenyllactic acid

Modifications
Strain Maximum production tyrA tyrB ppr trpE ptsH ptsI crr glf glk aroG pheA tktA pck
E. coli MG-P10 0.225 g/g of sustrate

Substrate yield in Flask for L-(-)-3-Phenyllactic acid

Modifications
Strain Maximum production ldhL fdh
E. coli BL21(pETDuet-ldhL-fdh) 0.961 g/g of sustrate

Volumetric productivity in Fed-Batch for L-(-)-3-Phenyllactic acid

Modifications
Strain Maximum production tyrA tyrB ppr trpE ptsH ptsI crr glf glk aroG pheA tktA pck
E. coli MG-P10 1,102 mg/L/h