Silencing
Overexpression
Feedback insensitive
Attenuation
Feed-forward insensitive
Inhibition insensitive
Unstated
Combined modifications
Titer in Flask for violacein
Modifications | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Strain | Maximum production | trpR | trpE | trpD | vioA | vioB | vioC | vioD | vioE | tnaA | pheA |
E. coli B1/pVio | 153 mg/L | ||||||||||
E. coli B6/pED + pVio | 531.9 mg/L | ||||||||||
E. coli B1/pED + pVio | 532 mg/L | ||||||||||
E. coli B5/pED + pVio | 543.8 mg/L | ||||||||||
E. coli B3/pED + pVio | 555.7 mg/L | ||||||||||
E. coli B8/pED + pVio | 558.7 mg/L | ||||||||||
E. coli B7/pED + pVio | 564.6 mg/L | ||||||||||
E. coli B4/pED + pVio | 582.4 mg/L | ||||||||||
E. coli B2/pED + pVio | 603 mg/L |
Titer in Fed-Batch for violacein
Modifications | |||||||||
---|---|---|---|---|---|---|---|---|---|
Strain | Maximum production | trpR | trpE | trpD | vioA | vioB | vioC | vioD | vioE |
E. coli B2/pED + pVio | 1,750 mg/L |
Volumetric productivity in Fed-Batch for violacein
Modifications | |||||||||
---|---|---|---|---|---|---|---|---|---|
Strain | Maximum production | trpR | trpE | trpD | vioA | vioB | vioC | vioD | vioE |
E. coli B2/pED + pVio | 36 mg/L/h |
Substrate yield in Flask for violacein
Modifications | |||||||||
---|---|---|---|---|---|---|---|---|---|
Strain | Maximum production | trpR | trpE | trpD | vioA | vioB | vioC | vioD | vioE |
E. coli B2/pED + pVio | 0.116 g/g of sustrate |