Silencing
Overexpression
Feedback insensitive
Attenuation
Feed-forward insensitive
Inhibition insensitive
Unstated
Combined modifications

Titer in Flask for violacein

Modifications
Strain Maximum production trpR trpE trpD vioA vioB vioC vioD vioE tnaA pheA
E. coli B1/pVio 153 mg/L
E. coli B6/pED + pVio 531.9 mg/L
E. coli B1/pED + pVio 532 mg/L
E. coli B5/pED + pVio 543.8 mg/L
E. coli B3/pED + pVio 555.7 mg/L
E. coli B8/pED + pVio 558.7 mg/L
E. coli B7/pED + pVio 564.6 mg/L
E. coli B4/pED + pVio 582.4 mg/L
E. coli B2/pED + pVio 603 mg/L

Titer in Fed-Batch for violacein

Modifications
Strain Maximum production trpR trpE trpD vioA vioB vioC vioD vioE
E. coli B2/pED + pVio 1,750 mg/L

Volumetric productivity in Fed-Batch for violacein

Modifications
Strain Maximum production trpR trpE trpD vioA vioB vioC vioD vioE
E. coli B2/pED + pVio 36 mg/L/h

Substrate yield in Flask for violacein

Modifications
Strain Maximum production trpR trpE trpD vioA vioB vioC vioD vioE
E. coli B2/pED + pVio 0.116 g/g of sustrate