Titer in Flask for shikimate

Modifications
Strain Maximum production aroL aroK ptsG pykF ydiB ackA pta aroG ppsA tktA
E. coli W3110 1.13 mg/L
E. coli B0013 1.63 mg/L
E. coli SA1 21.45 mg/L
E. coli SA2 67.81 mg/L
E. coli SA4* 385.62 mg/L
E. coli SA3 417.2 mg/L
E. coli SA4 576.17 mg/L
E. coli SA5 670.04 mg/L
E. coli SA5/pTH-aroG* 900 mg/L
E. coli SA5/pTH-aroG*-ppsA 1,080 mg/L
E. coli SA5/pTH-aroG*-ppsA-tktA 1,207 mg/L

Titer in Fed-Batch for shikimate

Modifications
Strain Maximum production aroL aroK ptsG ydiB ackA pta aroG ppsA tktA
E. coli SA5/pTH-aroG*-ppsA-tktA 14,600 mg/L

Substrate yield in Flask for shikimate

Modifications
Strain Maximum production aroL aroK ptsG ydiB ackA pta aroG ppsA tktA
E. coli SA5/pTH-aroG*-ppsA-tktA 0.0851 g/g of sustrate

Substrate yield in Fed-Batch for shikimate

Modifications
Strain Maximum production aroL aroK ptsG ydiB ackA pta aroG ppsA tktA
E. coli SA5/pTH-aroG*-ppsA-tktA 0.2925 g/g of sustrate

Volumetric productivity in Flask for shikimate

Modifications
Strain Maximum production aroL aroK ptsG ydiB ackA pta aroG ppsA tktA
E. coli SA5/pTH-aroG*-ppsA-tktA 47 mg/L/h

Volumetric productivity in Fed-Batch for shikimate

Modifications
Strain Maximum production aroL aroK ptsG ydiB ackA pta aroG ppsA tktA
E. coli SA5/pTH-aroG*-ppsA-tktA 260 mg/L/h