Titer in Flask for shikimate
Modifications | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Strain | Maximum production | aroL | aroK | ptsG | pykF | ydiB | ackA | pta | aroG | ppsA | tktA |
E. coli W3110 | 1.13 mg/L | ||||||||||
E. coli B0013 | 1.63 mg/L | ||||||||||
E. coli SA1 | 21.45 mg/L | ||||||||||
E. coli SA2 | 67.81 mg/L | ||||||||||
E. coli SA4* | 385.62 mg/L | ||||||||||
E. coli SA3 | 417.2 mg/L | ||||||||||
E. coli SA4 | 576.17 mg/L | ||||||||||
E. coli SA5 | 670.04 mg/L | ||||||||||
E. coli SA5/pTH-aroG* | 900 mg/L | ||||||||||
E. coli SA5/pTH-aroG*-ppsA | 1,080 mg/L | ||||||||||
E. coli SA5/pTH-aroG*-ppsA-tktA | 1,207 mg/L |
Titer in Fed-Batch for shikimate
Modifications | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Strain | Maximum production | aroL | aroK | ptsG | ydiB | ackA | pta | aroG | ppsA | tktA |
E. coli SA5/pTH-aroG*-ppsA-tktA | 14,600 mg/L |
Substrate yield in Flask for shikimate
Modifications | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Strain | Maximum production | aroL | aroK | ptsG | ydiB | ackA | pta | aroG | ppsA | tktA |
E. coli SA5/pTH-aroG*-ppsA-tktA | 0.0851 g/g of sustrate |
Substrate yield in Fed-Batch for shikimate
Modifications | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Strain | Maximum production | aroL | aroK | ptsG | ydiB | ackA | pta | aroG | ppsA | tktA |
E. coli SA5/pTH-aroG*-ppsA-tktA | 0.2925 g/g of sustrate |
Volumetric productivity in Flask for shikimate
Modifications | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Strain | Maximum production | aroL | aroK | ptsG | ydiB | ackA | pta | aroG | ppsA | tktA |
E. coli SA5/pTH-aroG*-ppsA-tktA | 47 mg/L/h |
Volumetric productivity in Fed-Batch for shikimate
Modifications | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Strain | Maximum production | aroL | aroK | ptsG | ydiB | ackA | pta | aroG | ppsA | tktA |
E. coli SA5/pTH-aroG*-ppsA-tktA | 260 mg/L/h |