Titer in Fed-Batch for (R)-pantothenate

		Modifications
Strain	Maximum production	ilvG	panB	panC	glk	avtA	ilvE	ldhA	poxB	gltA	ilvD	panE	gapC	gapC	sthA	ppnK	tolR	ompC
E. coli PA117	58,760 mg/L
E. coli PA132	83,260 mg/L

Titer in Flask for (R)-pantothenate

		Modifications
Strain	Maximum production	ilvG	panB	panC	glk	avtA	ilvE	ldhA	pta	poxB	gltA	ilvD	panE	gapC	gapC	ileY	ppnK	sthA	panB	panC	panC	panB	ilvB	ilvC	gapA	panF	ompA	ompC	ompF	tolR
E. coli PA126	35 mg/L
E. coli PA106	260 mg/L
E. coli PA101	285 mg/L
E. coli PA102	314 mg/L
E. coli PA104	330 mg/L
E. coli PA105	360 mg/L
E. coli PA103	461 mg/L
E. coli PA128	499 mg/L
E. coli PA127	506 mg/L
E. coli PA107pA	564 mg/L
E. coli PA129	598 mg/L
E. coli PA107	810 mg/L
E. coli PA107pF	890 mg/L
E. coli PA109	940 mg/L
E. coli PA107pR	978 mg/L
E. coli PA130	1,090 mg/L
E. coli PA111	1,210 mg/L
E. coli PA107pC	1,450 mg/L
E. coli PA111 pBs	2,722 mg/L
E. coli PA111 pCg	2,766 mg/L
E. coli PA120	3,379 mg/L
E. coli PA115	3,530 mg/L
E. coli PA111 pEc	3,710 mg/L
E. coli PA112	3,727 mg/L
E. coli PA124	3,740 mg/L
E. coli PA114	3,750 mg/L
E. coli PA118	3,845 mg/L
E. coli PA113	3,870 mg/L
E. coli PA116	3,890 mg/L
E. coli PA122	3,990 mg/L
E. coli PA121	4,020 mg/L
E. coli PA117	4,270 mg/L
E. coli PA119	4,330 mg/L
E. coli PA131	4,566 mg/L
E. coli PA123	4,820 mg/L
E. coli PA125	4,930 mg/L
E. coli PA132	5,040 mg/L

Volumetric productivity in Flask for (R)-pantothenate

		Modifications
Strain	Maximum production	ilvG	panB	panC	glk	avtA	ilvE	ldhA	poxB	gltA
E. coli PA112	50 mg/L/h
E. coli PA111 pEc	80 mg/L/h

Volumetric productivity in Fed-Batch for (R)-pantothenate

		Modifications
Strain	Maximum production	ilvG	panB	panC	glk	avtA	ilvE	ldhA	poxB	gltA	ilvD	panE	gapC	gapC	sthA	ppnK	tolR	ompC
E. coli PA132	1,740 mg/L/h

Substrate yield in Fed-Batch for (R)-pantothenate

		Modifications
Strain	Maximum production	ilvG	panB	panC	glk	avtA	ilvE	ldhA	poxB	gltA	ilvD	panE	gapC	gapC	sthA	ppnK	tolR	ompC
E. coli PA132	0.39 g/g of sustrate

Biomass-specific productivity in Flask for (R)-pantothenate

		Modifications
Strain	Maximum production	ilvG	panB	panC	glk	avtA	ilvE	ldhA	pta	poxB	aceE	gltA	icd	panB	panC	panC	panB	ilvD	panE	ilvC	ilvB	gapC	gapC	gapA	ompA	ompC	ompF	tolR
E. coli PA101	-999,999,999 mg/L/g DCW
E. coli PA102	-999,999,999 mg/L/g DCW
E. coli PA103	-999,999,999 mg/L/g DCW
E. coli PA104	-999,999,999 mg/L/g DCW
E. coli PA105	-999,999,999 mg/L/g DCW
E. coli PA106	-999,999,999 mg/L/g DCW
E. coli PA107	-999,999,999 mg/L/g DCW
E. coli PA108	-999,999,999 mg/L/g DCW
E. coli PA109	-999,999,999 mg/L/g DCW
E. coli PA110	-999,999,999 mg/L/g DCW
E. coli PA111 pEc	-999,999,999 mg/L/g DCW
E. coli PA111 pCg	-999,999,999 mg/L/g DCW
E. coli PA111 pBs	-999,999,999 mg/L/g DCW
E. coli PA117	-999,999,999 mg/L/g DCW
E. coli PA116	-999,999,999 mg/L/g DCW
E. coli PA115	-999,999,999 mg/L/g DCW
E. coli PA114	-999,999,999 mg/L/g DCW
E. coli PA113	-999,999,999 mg/L/g DCW
E. coli PA118	-999,999,999 mg/L/g DCW
E. coli PA119	-999,999,999 mg/L/g DCW
E. coli PA120	-999,999,999 mg/L/g DCW
E. coli PA121	-999,999,999 mg/L/g DCW
E. coli PA122	-999,999,999 mg/L/g DCW
E. coli PA107pA	-999,999,999 mg/L/g DCW
E. coli PA107pC	-999,999,999 mg/L/g DCW
E. coli PA107pF	-999,999,999 mg/L/g DCW
E. coli PA107pR	-999,999,999 mg/L/g DCW
E. coli PA127	-999,999,999 mg/L/g DCW
E. coli PA128	-999,999,999 mg/L/g DCW
E. coli PA129	-999,999,999 mg/L/g DCW
E. coli PA130	-999,999,999 mg/L/g DCW