Silencing
Overexpression
Feedback insensitive
Attenuation
Feed-forward insensitive
Inhibition insensitive
Unstated
Combined modifications

Titer in Fed-Batch for catechol

Modifications
Strain Maximum production trpD aroG tktA antA antB antC
E. coli W3110 trpD9923/pJLBaroGfbrtktA/pTrc-ant3 4,470 mg/L

Titer in Flask for catechol

Modifications
Strain Maximum production trpD antA antB antC aroG tktA ptsH ptsI crr
E. coli W3110 trpD9923/pTrc-ant3 150 mg/L
E. coli trpD9923 PTS-/pTrc-ant3 370 mg/L
E. coli W3110 trpD9923/pJLBaroGfbrtktA/pTrc-ant3 410 mg/L

Substrate yield in Fed-Batch for catechol

Modifications
Strain Maximum production trpD aroG tktA antA antB antC
E. coli W3110 trpD9923/pJLBaroGfbrtktA/pTrc-ant3 0.16 g/g of sustrate

Substrate yield in Flask for catechol

Modifications
Strain Maximum production trpD ptsH ptsI crr antA antB antC aroG tktA
E. coli W3110 trpD9923/pTrc-ant3 0.05 g/g of sustrate
E. coli trpD9923 PTS-/pTrc-ant3 0.09 g/g of sustrate
E. coli W3110 trpD9923/pJLBaroGfbrtktA/pTrc-ant3 0.1 g/g of sustrate

Biomass-specific productivity in Flask for catechol

Modifications
Strain Maximum production trpD ptsH ptsI crr antA antB antC
E. coli trpD9923 PTS-/pTrc-ant3 0.03 mg/L/g DCW

Specific production rate in Flask for catechol

Modifications
Strain Maximum production trpD antA antB antC aroG tktA
E. coli W3110 trpD9923/pTrc-ant3 50 mg/g DCW/h
E. coli W3110 trpD9923/pJLBaroGfbrtktA/pTrc-ant3 70 mg/g DCW/h

Specific production rate in Fed-Batch for catechol

Modifications
Strain Maximum production trpD aroG tktA antA antB antC
E. coli W3110 trpD9923/pJLBaroGfbrtktA/pTrc-ant3 20 mg/g DCW/h