Titer in Flask for L-histidine

		Modifications
Strain	Maximum production	hisL	hisG	hisD	hisC	hisB	hisH	hisA	hisF	hisI	tdcD	hisG	ylbE	ilvG	trpR	prsA	purR	zwf	gnd	pgi	mazG	ushA	umpG	yjjG	yrfG	amn	ppnN	purH	rph	ycjV	purA	rpnD	purB	purF	yjhE	rocG	yjiT	lysE	argO
E. coli HW1	80 mg/L
E. coli HW1-1	120 mg/L
E. coli HW1-2	240 mg/L
E. coli HW1-5	830 mg/L
E. coli HW2-1	1,300 mg/L
E. coli HW2-2	1,400 mg/L
E. coli HW2-3	2,800 mg/L
E. coli HW2-4	3,800 mg/L
E. coli HW3-2	4,000 mg/L
E. coli HW3-1	4,200 mg/L
E. coli HW3-3	4,600 mg/L
E. coli HW3-4	4,900 mg/L
E. coli HW3-5	4,900 mg/L
E. coli HW4-1	5,400 mg/L
E. coli HW4-2	5,600 mg/L
E. coli HW4-4	7,300 mg/L
E. coli HW4-5	8,200 mg/L
E. coli HW5-1	10,100 mg/L
E. coli HW6-4	10,100 mg/L
E. coli HW6-3	11,800 mg/L

Titer in Fed-Batch for L-histidine

		Modifications
Strain	Maximum production	hisL	hisG	hisD	hisC	hisB	hisH	hisA	hisF	hisI	tdcD	hisG	ylbE	ilvG	trpR	prsA	purR	zwf	gnd	mazG	ushA	umpG	yjjG	yrfG	amn	ppnN	purH	rph	ycjV	purA	rpnD	purB	purF	yjhE	rocG	yjiT	lysE
E. coli HW6-3	66,500 mg/L

Volumetric productivity in Fed-Batch for L-histidine

		Modifications
Strain	Maximum production	hisL	hisG	hisD	hisC	hisB	hisH	hisA	hisF	hisI	tdcD	hisG	ylbE	ilvG	trpR	prsA	purR	zwf	gnd	mazG	ushA	umpG	yjjG	yrfG	amn	ppnN	purH	rph	ycjV	purA	rpnD	purB	purF	yjhE	rocG	yjiT	lysE
E. coli HW6-3	1,500 mg/L/h

Substrate yield in Fed-Batch for L-histidine

		Modifications
Strain	Maximum production	hisL	hisG	hisD	hisC	hisB	hisH	hisA	hisF	hisI	tdcD	hisG	ylbE	ilvG	trpR	prsA	purR	zwf	gnd	mazG	ushA	umpG	yjjG	yrfG	amn	ppnN	purH	rph	ycjV	purA	rpnD	purB	purF	yjhE	rocG	yjiT	lysE
E. coli HW6-3	0.23 g/g of sustrate