an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

H₂O

glycerone phosphate

3-methyl-2-oxobutanoate

(S)-3-methyl-2-oxopentanoate

(R)-2,3-dihydroxy-3-methylpentanoate

prephenate

N-acetylglutamyl-phosphate

N-acetyl-L-glutamate 5-semialdehyde

nicotinate adenine dinucleotide

thiamine diphosphate

thiamine phosphate

5-methylcytosine

quinolinate

β-nicotinate D-ribonucleotide

CO₂

D-erythro-imidazole-glycerol-phosphate

2-oxovalerate

3-ethylmalate

4-methyl-2-oxopentanoate

(2S)-2-isopropyl-3-oxosuccinate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

(2S)-2-isopropylmalate

(indol-3 yl)acetyl-CoA

(indol-3-yl)pyruvate

coproporphyrinogen III

dihydromethanophenazine

methanophenazine

H₂

CoB-CoM heterodisulfide

coenzyme B

histidinol

histidinal

L-histidinol phosphate

imidazole acetol-phosphate

3-deoxy-α-D-manno-2-octulosonate

succinate semialdehyde

(4S)-4-hydroxy-2-oxoheptanedioate

phosphoenolpyruvate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

acetyl phosphate

L-canavanine

canavaninosuccinate

L-arginino-succinate

citrate

hydrogen peroxide

O-acetyl-L-serine

hydrogenobyrinate a,c-diamide

β-D-ribosylnicotinate

shikimate 3-phosphate

shikimate

N-(5-phosphoribosyl)-anthranilate

anthranilate

5-oxo-L-proline

3-ureidopropanoate

(4,5-dihydro-5-oxofuran-2-yl)-acetate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

oxaloacetate

3-dehydroshikimate

3-dehydroquinate

glycolate

hydrogenobyrinate

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-amino-6-(5-phospho-D-ribitylamino)uracil

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

N¹-(5-phospho-β-D-ribosyl)glycinamide

O-ureido-L-homoserine

(2S)-lactyl-2-diphospho-5'-guanosine

7,8-didemethyl-8-hydroxy-5-deazariboflavin

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

2-dehydropantoate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

5-phospho-β-D-ribosylamine

4-aminobutanoate

formamide

5-enolpyruvoyl-shikimate 3-phosphate

3-deoxy-D-arabino-heptulosonate 7-phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

orotidine 5'-phosphate

hexulose 6-phosphate

γ-L-glutamyl 5-phosphate

carbamoyl phosphate

L-β-lysine

(S)-2-aceto-2-hydroxybutanoate

(S)-2-acetolactate

5-amino-6-(D-ribitylamino)uracil

1-deoxy-L-glycero-tetrulose 4-phosphate

N⁵-carboxyaminoimidazole ribonucleotide

carbon monoxide

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

3-phosphooxypyruvate

(R)-mevalonate

7-carboxy-7-deazaguanine

N-Formyl-L-kynurenine

α-ribazole 5'-phosphate

α-ribazole

2-phosphoglycolate

isopentenyl diphosphate

(R)-5-phosphomevalonate

prenyl diphosphate

dihydrogeranylgeranyl diphosphate

tetrahydrogeranylgeranyl diphosphate

S-Inosyl-L-homocysteine

5-deoxy-α-ribose 1-phosphate

S-methyl-5-thio-α-D-ribose 1-phosphate

S-methyl-5'-thioadenosine

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

5-(methylsulfanyl)-ribulose 1-phosphate

4'-phosphopantetheine

2'-(5''-triphospho-α-D-ribosyl)-3'-dephospho-CoA

(R)-4'-phosphopantothenate

(R)-pantothenate

(R)-4'-phosphopantothenoyl-L-cysteine

coenzyme F₃₉₀-A

(S)-dihydroorotate

(R)-1-amino-2-propanol O-2-phosphate

urea

DNA without lesion

carboxyphosphate

carbonic acid

preuroporphyrinogen

porphobilinogen

5-aminolevulinate

(S)-4-amino-5-oxopentanoate

(R)-mevalonate diphosphate

oxalate

2-(sulfomethyl)thiazolidine-4-carboxylate

sulfoethylcysteine

autoinducer 2

S-ribosyl-L-homocysteine

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

1,2-dihydro-β-NADP

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

enol-phenylpyruvate

ammonia

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

preQ₀

hydrogen cyanide

(indole-3-yl)acetonitrile

D-alanyl-D-alanine

L-kynurenine

carbamate

L-citrulline

L-glutamate

L-glutamine

L-alanine

L-phenylalanine

L-tryptophan

L-histidine

L-valine

L-arginine

L-isoleucine

L-serine

L-threonine

L-leucine

L-aspartate

L-tyrosine

L-lysine

glycine

L-cysteine

L-methionine

L-ornithine

L-homocysteine

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

L-homoserine

O-phospho-L-homoserine

L-canaline

L-aspartate 4-semialdehyde

meso-diaminopimelate

L-aspartyl-4-phosphate

L-threonine 3-O-phosphate

3-phospho-L-serine

O-acetyl-L-homoserine

N-carbamoylglycine

N-acetyl-L-ornithine

N-acetyl-L-citrulline

N-acetyl-L-glutamate

N-carbamoyl-L-aspartate

L,L-diaminopimelate

D-alanine

(R)-β-lysine

β-alanine

pyruvate

acetate

formate

(R)-lactate

(S)-lactate

(R)-pantoate

5-chloro-5-deoxy-D-ribonate

orotate

pristanate

palmitate

stearate

decanoate

laurate

7-hydroxylaurate

octanoate

18-hydroxyoleate

16-hydroxypalmitate

18-hydroxystearate

phytenate

(15Z)-tetracosenoate

oleate

linoleate

α-linolenate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

2-oxoglutarate

5-chloro-4-hydroxy-2-oxopentanoate

2-oxobutanoate

(2R)-homocitrate

cis-aconitate

cis-homoaconitate

D-threo-isocitrate

3-(carbamoylamino)-2-methylpropanoate

chorismate

α,ω-9Z-octadecenedioate

fumarate

succinate

(S)-malate

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

phytyl diphosphate

(2E,6E)-farnesyl diphosphate

di-trans,octa-cis-undecaprenyl phosphate

di-trans,octa-cis-undecaprenyl diphosphate

geranylgeranyl diphosphate

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

1-(β-D ribofuranosyl)nicotinamide

D-glyceraldehyde 3-phosphate

α-D-glucopyranose 1-phosphate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

GDP-α-D-mannose

dTDP-α-D-glucose

dTDP-4-dehydro-β-L-rhamnose

dTDP-β-L-rhamnose

UDP-α-D-galactose

UDP-α-D-glucose

UDP-α-D-glucuronate

UDP-α-D-galactofuranose

CMP-3-deoxy-β-D-manno-octulosonate

5-phospho-α-D-ribose 1-diphosphate

D-sedoheptulose 7-phosphate

D-erythrose 4-phosphate

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

β-D-fructofuranose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructose 1,6-bisphosphate

β-D-fructofuranose 6-phosphate

D-fructose 6-phosphate

2-deoxy-α-D-ribose 1-phosphate

D-xylulose 5-phosphate

D-ribulose 5-phosphate

D-ribulose-1,5-bisphosphate

β-D-fructofuranose

α-D-galactopyranose

D-glyceraldehyde

keto-D-fructose

sucrose

raffinose

stachyose

ethanol

methanol

methylglyoxal

acetaldehyde

formaldehyde

caldariellaquinone

diacetyl

caldariellaquinol

tyramine

indole

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

adenine

AMP

GMP

XMP

IMP

ATP

ITP

GTP

ADP

IDP

GDP

dADP

dIDP

dGDP

dATP

dITP

dGTP

hypoxanthine

adenosine

inosine

guanosine

xanthosine

tetrahydromethanopterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

6-carboxy-5,6,7,8-tetrahydropterin

molybdopterin

cyclic pyranopterin phosphate

7,8-dihydroneopterin 3'-triphosphate

molybdopterin adenine dinucleotide

5-formyl-tetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

tetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

guanylyl molybdenum cofactor

MoO₂-molybdopterin cofactor

reduced riboflavin

FMNH₂

riboflavin

FMN

FAD

6,7-dimethyl-8-(1-D-ribityl)lumazine

thymine

uracil

cytosine

UDP

CTP

UTP

dTTP

dTDP

dTMP

dCDP

dCMP

CDP

dCTP

dUTP

dUDP

5,6-dihydrothymine

5,6-dihydrouracil

dUMP

UMP

CMP

cytidine

uridine

thymidine

2'-deoxycytidine

2'-deoxyuridine

5-fluorouracil

hydantoin

cob(I)alamin

adenosylcobalamin

cobyrinate

sirohydrochlorin

cobalt-precorrin-3

cobalt-precorrin-2

cobalt-precorrin-5A

cobalt-precorrin-4

precorrin-8x

cobalt-precorrin-6A

cobalt-precorrin-5B

precorrin-2

precorrin-1

cobalt-precorrin-6B

cobalt-precorrin-8

cobalt-precorrin-7

precorrin-3A

precorrin-3B

precorrin-4

precorrin-5

precorrin-6A

precorrin-6B

precorrin-7

coenzyme A

methyl-CoM

coenzyme M

oxidized coenzyme F₄₂₀-0

oxidized coenzyme F₄₂₀-2

5'-deoxyadenosine

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

adenylo-succinate

β-nicotinamide D-ribonucleotide

NADP⁺

NAD⁺

NADPH

NADH

(S)-NADPHX

(R)-NADPHX

5-fluorocytosine

glycine betaine

(S)-NADHX

(R)-NADHX

nicotinate

pyridoxal 5'-phosphate

pyridoxine 5'-phosphate

pyridoxamine 5'-phosphate

(indol-3-yl)acetate

phenylacetate

(25S)-3-oxocholest-4-en-26-oyl-CoA

(25S)-3-oxocholest-4-en-26-oate

methane

acetyl-CoA

succinyl-CoA

linoleoyl-CoA

α-linolenoyl-CoA

phenylacetyl-CoA

2-methylacetoacetyl-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

3'-dephospho-CoA

ω-carboxy-(9Z)-octadec-9-enoyl-CoA

oleoyl-CoA

3-oxopentanoyl-CoA

acetoacetyl-CoA

16-hydroxypalmitoyl-CoA

palmitoyl-CoA

stearoyl-CoA

18-hydroxyoleoyl-CoA

18-hydroxystearoyl-CoA

pristanoyl-CoA

decanoyl-CoA

lauroyl-CoA

7-hydroxylauroyl-CoA

octanoyl-CoA

propanoyl-CoA

(Z)-15-tetracosenoyl-CoA

phytenoyl-CoA

L-cysteate

3-sulfopyruvate

sulfoacetaldehyde

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

methanethiol

agmatine

spermidine

dehydrospermidine

putrescine

2-chloroacetate

Mo²⁺

Mg²⁺

Co²⁺

Fe²⁺

H⁺

K⁺

ammonium

nitrate

tungstate

sulfite

hydrogencarbonate

molybdate

chloride

phosphate

diphosphate

triphosphate

(S)-citramalate

(2R)-2,3-dihydroxy-3-methylbutanoate

(2S)-2-phospholactate

ω-saturated C55 dolichol phosphate

3-phospho-D-glyceroyl-phosphate

3-phospho-D-glycerate

2-phospho-D-glycerate

β-D-mannosyl-(C55 ω-saturated dolichyl phosphate)

2-iminosuccinate

oxygen

hydrogen sulfide

protoporphyrinogen IX

Mg-protoporphyrin

protoporphyrin IX

coproporphyrinogen I

uroporphyrinogen-I

uroporphyrinogen-III

siroheme

cob(II)yrinate a,c-diamide

cob(II)yrinate c-monoamide

adenosylcobyrate

adenosyl-cob(III)yrinate a,c-diamide

adenosylcobalamin 5'-phosphate

adenosylcobinamide-GDP

cobalt-sirohydrochlorin

cobalt-factor III

DNA with lesion